Gene CCRK (Mouse)

CCRK

Species: Mouse
Alias: CCRK, 4932702G04Rik
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CCRK

Sequence

Name Sequence Type Origin Length Description Download
CCRK.AA Protein Sugen 346 None Fasta, JSON
CCRK.NA RNA Sugen 1780 None Fasta, JSON
CCRK.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 285 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of CCRK.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CCRK.AA CCRK 4-288 89 3.5e-246 824.15 In-house 1-285 (285) Show / Hide 
Range on Protein: 4-288
Range on HMM: 1-285/285
Sequence Identity: 89% (256 aa)

YCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQALREIKALQEIEDSQYVVQLKAVFPHGAGFVLAFEFMLSDLAEVVRHAQRPLAPAQ
||||.||||||||||||||||||||||||||||||||.|||||||||||||||||||.|||||||.|||||.||||.||||||||||||||||||||.||
YCILDRIGEGAHGIVFKAKHVETGEIVALKKVALRRLDDGIPNQALREIKALQEIEDNQYVVQLKDVFPHGTGFVLVFEFMLSDLAEVVRHAQRPLAEAQ

VKSYLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGGRLYTHQVATRWYRAPELLYGARQYDQGVDLWAVGCIMGELLNGSPL
||||.||||||||.||.|||.||||||||||||.||.|||||||||||||.|.||.||||||||||||||||||||||||||||||||||||||||.||.
VKSYMQMLLKGVAHCHENNIMHRDLKPANLLISESGHLKIADFGLARVFSNDEGRQYTHQVATRWYRAPELLYGARQYDQGVDLWAVGCIMGELLNNSPI

FPGENDIEQLCCVLRILGTPSPRVWPEITELPDYNKISFKEQAPVPLEEVLPDASPQALDLLGQFLLYPPRQRIAASQALLHQYF
||||||||||||||||||||.|.||||...||||||||||||.|.|||.|.|||||||||||.|||.||||||||||||||||||
FPGENDIEQLCCVLRILGTPTPKVWPEMKDLPDYNKISFKEQPPMPLEQVVPDASPQALDLLKQFLVYPPRQRIAASQALLHQYF
Kinase CCRK.AA CDK 4-288 37 2.5e-150 484.27 In-house 1-284 (284) Show / Hide 
Range on Protein: 4-288
Range on HMM: 1-284/284
Sequence Identity: 37% (122 aa)

YCILGRIGEGAHGIVFKAKHVETG-----EIVALKKVALRR-----LEDGIPNQALREIKALQEIEDSQYVVQLKAVFPHG-----------AGFVLAFE
|..| .||||..|.|.||.. .||     .||||||. .        ..|.|  |.|||. |.|.   ...|.|. |...              ... ||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFE

FMLSDLAEVVRHAQRPLAPAQVKSYLQMLLKGVAFCHANNIVHRDLKPANLLISASGQ-----LKIADFGLARVFSP----DGG--RLYTHQVATRWYRA
.|  ||... .          .|.|...||.|...|| |.|.||||||.|.||.  |.     |||||||||| |.     . .  | |||.| |.||||
YMDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMS-EPNRTYTHEVVTLWYRA

PELLYGARQYD--QGVDLWAVGCIMGELLN---GSPLFPGENDIEQLCCVLRILGTPSPRVWPEITELPDYNKISFKEQAPVPLEEVLPDASPQALDLLG
|||| |...|.   ..|.|.||||..|...   . |||||...|.||... ||.|||.. .||..|.||||                         ||| 
PELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY-------------------------DLLN

QFLLYPPRQRIAASQALLHQYF
..| | | .|| |.||| |.||
KMLCYDPKKRISAEQALQHPYF
Kinase CCRK.AA CDK7 4-288 45 7.2e-141 378.08 In-house 1-288 (288) Show / Hide 
Range on Protein: 4-288
Range on HMM: 1-288/288
Sequence Identity: 45% (133 aa)

YCILGRIGEGAHGIVFKAKHVETGEIVALKKVA----LRRLEDGIPNQALREIKALQEIEDSQYVVQLKAVFPHGAGFVLAFEFMLSDLAEVVRHAQRPL
| ..  ||||  . |.||   .||.||| ||.         .|||   |.|||| |||..    |. |  .| |     | |.||  || .|..  .  |
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQH-DNVIGLIDIFMHKSNIQLVFDFMDWDLEVVIKDKSIIL

APAQVKSYLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVF-SPDGGRLYTHQVATRWYRAPELLYGARQYDQGVDLWAVGCIMGELL
 || .|.|  |.|.|. .||.| | |||||| |||..  |||||||||||| . ||   | ||||| ||||||||||.|||.|  |||.|.||||. ||.
TPAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPN--RIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAELM

NGSPLFPGENDIEQLCCVLRILGTPSPRVWPEITELPDYNKISFKEQAP---VPLEEVLPDASPQALDLLGQFLLYPPRQRIAASQALLHQYF
   | .||..|| ||  . ..||||... ||......||.|  ||.. .   .||...   ||  .|||.   ..  | .|. ..|.| . ||
LRVPYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMMDYIK--FKDFPGYSRTPLRHIFTAASDDLLDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase CCRK.AA CMGC 4-288 25 8e-130 429.15 In-house 1-513 (513) Show / Hide 
Range on Protein: 4-288
Range on HMM: 1-513/513
Sequence Identity: 25% (132 aa)

YCILGRIGEGAHGIVFKAKH--------------VETGEIVALKKVALRR---------LEDGIPNQALREIKALQEIE----------------DSQYV
| |...||||. |.|.|...               ||.||||.||. ..          ..||.|  |||||| |...                 .  ..
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VQLKAVFPHGA-----------------GFVLAFEFMLSDLAEVVRHAQ--------RPLAPAQ------------VKSYL------QMLLKGVA--FCH
|.|. .| |                    . | ||.|  ||... .. |        .|| . .            .|...      ...|.|..  .||
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

ANN--IVHRDLKPANLLISAS--------------------GQLKIADFGLARVFSPDG--------------------GRLYTHQVATRWYRAPELLYG
 ..  |.||||||.|.||.                      |.|||.|||||| ..|                      .| |||.|.||||||||.| |
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG

ARQYD---------QGVDLWAVGCIMGELLNG--------SPLFPGEND-----------IEQLCCVLRILGTPS---------------PRVWPEITEL
...|.         ...| |.||||..|...|         |||||...           |.|| .  ..||||.               .. ||....|
WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKL

PDYNK-------------IS------------FKEQAPVPLEEVLPD-----------------------------------ASPQALDLLGQFLLYPPR
|.|||             .|            |... | |.... |.                                   ..|||.||| . | | | 
PWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPD

QRIAASQALLHQYF
.|| |.||| | ||
KRITAEQALQHPYF
Kinase CCRK.AA CDC2 4-288 42 4.8e-120 370.79 In-house 1-301 (301) Show / Hide 
Range on Protein: 4-288
Range on HMM: 1-301/301
Sequence Identity: 42% (128 aa)

YCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDG--IPNQALREIKALQEIEDSQYVVQLKAVFPHGAGFVLAFEFMLSDLAEVVR-HAQ--RP
|. . .||||  |.|.|.|...|..||||||. | . ..|  .|  |.|||  |.|. | . .|.|. |.       . ||..  || .  .   .   .
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKNKH

LAPAQVKSYLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGGRLYT--HQVATRWYRAPELLYGARQYDQGVDLWAVGCIMGE
. |. ||||.  .|.||.|||.. |.|||||| |.||...|..||||||||| |.    | ||  | | |.||||||.| |...|. .||.|..|||. |
MPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIP-IRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAE

L---LNGSPLFPGENDIEQLCCVLRILGTPSPRVWPEITELPDYNKISFKEQAPVPLEEVLPD---------ASPQALDLLGQFLLYPPRQRIAASQALL
.    .  |||.|.  |.||. . ||||||.   ||..|.|||| | .| .  |  |....|.         . |...||| | | | | .|| | .|| 
MFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDY-KNTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQ

HQYF
| ||
HPYF
Kinase CCRK.AA CDK5 4-288 41 1.8e-105 334.31 In-house 1-287 (287) Show / Hide 
Range on Protein: 4-288
Range on HMM: 1-287/287
Sequence Identity: 41% (121 aa)

YCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQALREIKALQEIEDSQYVVQLKAVFPHGAGFVLAFEFMLSDLAEVVRHAQRPLAPAQ
|  . .||||  |.|.||.  ||.||||||.| |     |.|  |.|||  |.|.   . .| |  |       .| |||.  ||       .  . .. 
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKH-KNIVRLHDVIHSEKKLTLVFEFCDQDLKKYMDSCNGEMDMHI

VKSYLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFS-PDGGRLYTHQVATRWYRAPELLYGARQYDQGVDLWAVGCIMGELL-NGS
.||..  ||||.||||.... |||||| ||||.  |.|| ||||||| |  |   | |.| | | |||.|  | |...|   .|.| .|||. |.  .| 
IKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIP--VRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAGR

PLFPGENDIEQLCCVLRILGTPSPRVWPEITELPDYN--KISFKEQAPVP-LEEVLPDASPQALDLLGQFLLYPPRQRIAASQALLHQYF
||||| .. .||  . .|.|||.   || ||.||||.     .    . . .... |  . . .|||.. | . | ||| | .|| |.||
PLFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase CCRK.AA S_TKc 4-288 26 1.1e-89 305.15 SMART 1-231 (231) Show / Hide 
Range on Protein: 4-288
Range on HMM: 1-231/231
Sequence Identity: 26% (81 aa)

YCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQALREIKALQEIEDSQYVVQLKAVFPHGAGFVLAFEFMLS---DLAEVVRHAQRP--
| ||  ||.|| | |.|..|..||.|||.|..          ....|||. |..  .  ..|.|. || .   . . .|..     || .. .. .|.  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LAPAQVKSYLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGGRLYTHQVATRWYRAPELLYGARQYDQ-GVDLWAVGCIM
   . . ....|.. .......|| ..|.||||||.|.|..   ..||.||||||..        |... |.||.|||.|    .|.   .| |..|||.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCIL

GELLNGSPLFPGENDIEQLCCVLRILGTPSPRVWPEITELPDYNKISFKEQAPVPLEEVLPDASPQALDLLGQFLLYPPRQRIAASQALL-------HQY
 |.| | |.||   .....  ...                                       ||.|.|.. . | . |..|. | .||        |..
YEMLCGYPPFP---QMQMMFKKIG---------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPW

F
|
F
Kinase CCRK.AA Pkinase 4-288 29 9.9e-86 295.92 Pfam 1-293 (293) Show / Hide 
Range on Protein: 4-288
Range on HMM: 1-293/293
Sequence Identity: 29% (90 aa)

YCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQALR--EIKALQEIEDSQYVVQLKAVFPHGAGFVLAFEFMLS-----DLAEVVR-HA
|.|...||.|. | |.|..|. ||.|||.|.. .|. ... . ...|  ||. .... .. ..|.|. .|  .    . .|..       ||..... ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

QRPL--APAQVKSYLQMLLKGVAFCHANNIVHRDLKPANLLISASGQL----KIADFGLARVFSPDGGRLYTHQVATRWYRAPELLYGARQYDQGVDLWA
....   . ..|.|.  .|.|...||...|.||||||.|.||.  |..    ||.|||||..|.   .. .|. . |.||.|||.. |.. |.. || |.
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

VGCIMGELLNGSPLFPGE----NDIEQLCCVLRILGTPSPRVWPEITELPDYNKISFKEQAPVPLEEVLPDASPQALDLLGQFLLYPPRQRIAASQALLH
.|||. |.|.| |.|||.    | ..|. .. ||.|.| .. ||.  . .... ... . .   .... . .|. ..|..   | . | .|. | |.| |
CGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQH

QYF
 .|
PWF
Kinase CCRK.AA CDK-Unclassified 4-288 29 2.7e-85 280.54 In-house 1-324 (324) Show / Hide 
Range on Protein: 4-288
Range on HMM: 1-324/324
Sequence Identity: 29% (95 aa)

YCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLED----------GIPNQALREIKALQEIEDSQYVVQLKAVFPHGAGFV-------------LA
| ..  .|||..|.|.|| . .|  .|| ||...    .           ..  ..|||. ||  ..  ..  .  ...   .               . 
YRMQCKYGEGTFGCVCKAIDFQTQKHVAIKKIMVNNKKGNKCKHILPLLNSKITDQREISCLQNCNH-MNIIKFMDMHYDHDRCSKNPYYDNLHPSFYMV

FEFMLSDLAEVVRHAQRPLAPAQVKSYLQMLLKGVAFCHANNIVHRDLKPANLLISASG-----QLKIADFGLARVFS----------PDG-GRLYTHQV
 | |  ..  .      .|   |.. ..  .|.| |. | | | |||.||.|..|.  .      |||||||.|.             | . ...|. ||
MEYMPYTWYNQLHNNRYNLSMCQIRNFMHQMLEGIAYLHCNKIMHRDIKPQNIMITNNNSTVSPMLKIADFGQACFYMNCPPNLNYQTPADPMQQYSTQV

ATRWYRAPELLYGARQYDQGVDLWAVGCIMGELLNGSPLFPGENDIEQLCCVLRILGTPSPRVWPEITELPDYNKISFKEQAPVP-LEEVLPDASPQALD
.|||||||||| | ..|| ||| |..|||. |.. | |.|.| ..|||.  . ..||||.   ||... .|||.|| ||   .    .. .   .   ..
STRWYRAPELLFGSKCYDTGVDIWSFGCIYAEWFQGKPIFQGRTEIEQMHHIFKMLGTPCEDMWPDWRYMPDYCKIFFKYKQKFHWWNRFPKCKHASENN

LLGQFLLYPPRQRIAASQALLHQYF
...| . | |  |  ....| | .|
CEFQMVMYQPYNRWKCMEILQHPWF
Kinase CCRK.AA CRK7 4-288 32 1e-82 281.15 In-house 1-343 (343) Show / Hide 
Range on Protein: 4-288
Range on HMM: 1-343/343
Sequence Identity: 32% (113 aa)

YCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRL---EDGIPNQALREIKALQEIEDSQYVVQLKAVFPHG----------AGFVLAFEFMLSDLAE
| ... ||||  | | |||  .|||.|||||| .      ..| |  | |||| |..  . | .|.|| .              . | . || |  ||. 
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREIKILRQL-NHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDLMG

VVRHA-QRPLAPAQVKSYLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDG-GRLYTHQVATRWYRAPELLYGARQY-------
  .       .. |.|...  || |.. || .|. |||.| .|.|.  .|..||||||||| . ..   | ||  | | |||.|||| |. .|       
LLESKEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQHILK

-------------------------------DQGVDLWAVGCIMGELLNGSPLFPGENDIEQLCCVLRILGTPSPRVWPEITELPDYNKISFKE--QAPV
                                  .| | .|||.|||... |.|.|.| ..||  . .| |.| | .|||...|| .| .  |   .  .
ELIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYKICGSPNPNNWPEVMKLPWWNTMKPKRQYNRRL

PLEEVLP-----DASPQALDLLGQFLLYPPRQRIAASQALLHQYF
 .||.         ....|||| . | . |  |. |...| |..|
-REEFYHHKKPVFMPKECLDLLDKMLCLDPKKRFTAEECLQHDWF
Kinase CCRK.AA CDKL 4-288 38 5.3e-81 275.42 In-house 1-286 (286) Show / Hide 
Range on Protein: 4-288
Range on HMM: 1-286/286
Sequence Identity: 38% (111 aa)

YCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQALREIKALQEIEDSQYVVQLKAVFPHGAGFVLAFEFMLSDLAEVVRHAQRPLAPAQ
| .||..|||. | |.| .. |||.||| ||    . .  .   |.|||| |      .  |.|. ||       | ||..   . ..  . .. . . .
YEKLGKVGEGSYGVVMKCRNKETGQIVAIKKFKESEDDPMVKKIAMREIKMLKQLKH-ENIVNLIEVFRRKRKLHLVFEYCDHTVLHELEEYPNGVDEHV

VKSYLQMLLKGVAFCHANNIVHRDLKPANLLIS-ASGQLKIADFGLARVFSPDGGRLYTHQVATRWYRAPELLYGARQYDQGVDLWAVGCIMGELLNGSP
|..|.  .||...||| .|..||| || |.||. ..||.|. |||.||   .  |  ||  |||||||||||| | .||   ||.||.||.|.|.. | |
VRKYMWQILKAINFCHKHNCIHRDIKPENILITPKNGQVKLCDFGFAR-MLAKPGEIYTDYVATRWYRAPELLVGDTQYGKPVDIWAIGCVMAEMIDGQP

LFPGENDIEQLCCVLRILGTPSPRVWPEITELPDYNKISFKE-QAPVPLEEVLPDAS-PQALDLLGQFLLYPPRQRIAASQALLHQYF
|.||..|| ||    . ||.  ||        | .  ..| | . . |||. .|..| . |||.. . |   |..|. ..|.. | ||
LWPGQSDIDQLYHIQKCLGPLIPRHQEIFSKNPFFHGMKFPEIEHMEPLEKRYPNKSNKKALDFMKKCLHMDPDERMTCEQLMHHPYF
Kinase CCRK.AA PITSLRE 79-288 42 1.2e-74 254.34 In-house 80-295 (295) Show / Hide 
Range on Protein: 79-288
Range on HMM: 80-295/295
Sequence Identity: 42% (92 aa)

LAFEFMLSDLAEVVRHAQ---RPLAPAQVKSYLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVF-SPDGGRLYTHQVATRWYRAPEL
...|..  ||. .    .    |  | ..|. .| ||.||.. | | | ||||| .|||.| .|.|||.|||||| . ||   . ||  | | |||||||
MVMEYVEHDLKSLMENMKRRNQPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSP--IKPYTPCVVTLWYRAPEL

LYGARQYDQGVDLWAVGCIMGELLNGSPLFPGENDIEQLCCVLRILGTPSPRVWPEITELPDYNKIS-FKEQAPVPLEEVLP---DASPQALDLLGQFLL
| |.. |   ||.| ||||..|.. . |||.|...|.|. |.   .|||. . || .||||  ...  |... .  | .  |     | ...||| |.| 
LLGCKKYSTPVDMWSVGCIFAEFITMKPLFQGKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNNFPHYPYNNLRKRFPAENHISDTGFDLLNQMLT

YPPRQRIAASQALLHQYF
| | .|| ||.|| | .|
YNPKNRITASDALKHPWF
Kinase CCRK.AA PITSLRE 4-58 39 3.5e-15 51.88 In-house 1-58 (295) Show / Hide 
Range on Protein: 4-58
Range on HMM: 1-58/295
Sequence Identity: 39% (23 aa)

YCILGRIGEGAHGIVFKAKHVETGEIVALKKVALR--RLEDGIPNQALREIK-ALQEI
. .| ||.||. |.|..||  .|.||||||.. .   .  .|.|  .||||.  | ..
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMAL
Kinase CCRK.AA TyrKc 4-288 19 3.3e-12 -25.32 SMART 1-280 (280) Show / Hide 
Range on Protein: 4-288
Range on HMM: 1-280/280
Sequence Identity: 19% (60 aa)

YCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQALREIKALQEI-EDSQYVVQLKAVFPHG-------AGFVLAFEFMLS-DLAEVVRH
   .  .|||| |.|.|..     . || |..             .||.. . ..  . . .|.| .|  ..           . .|.|   || .  | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

AQRPLAPAQVKSYLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPD-----GGRLYT------HQ--VATRWYRAPELLYGARQY
 .. | ...  |.     .| .. | .|..||||   | |... .. ||.||||.|    |      .  |.          .  ||. ||| .   . .
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM-APECI-NYGKF

DQGVDLWAVGCIMGELL-NGSPLFPGE----NDIEQLCCVLRILGTPSPRVW--PEITELPDYNKISFKEQAPVPLEEVLPDASPQALDLLGQFLLYPPR
    | |. |  | |.. .| .  ||.     . ...   ..  . . .     | .                       . ...   ..  |   . | 
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYP-MS--------------------F-VCCPDEMYQIMKQCWHEDPE

QRIAASQALLHQYF
.|   |.   |..|
DRPTFSEI--HECF
Kinase CCRK.AA Pkinase_Tyr 4-150 26 4.6e-10 34.71 Pfam 1-159 (270) Show / Hide 
Range on Protein: 4-150
Range on HMM: 1-159/270
Sequence Identity: 26% (43 aa)

YCILGRIGEGAHGIVFKAKHV----ETGEIVALKKVALRRLEDGIPNQA------LREIKALQEIEDSQYVVQLKAVFP-HGAG--FVLAFEFMLS-DLA
  ..  .|||| | |.|..      .|.  || |..      .|   ..      .||.| . .. . . .|.| .|   .|      . .|.|   || 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK-----EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLL

EVVRHA---QRPLAPAQVKSYLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLAR
.  |     ..|| . .  .. .   || .. ...|..||||   | |.. ... ||.||||||
DYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR