Gene DRAK2 (Mouse)

DRAK2

Species: Mouse
Alias: DRAK2, AI120141
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: CAMK
Family: DAPK
Subfamily: DRAK

Sequence

Name Sequence Type Origin Length Description Download
DRAK2.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 260 Kinase domain by global Sugen HMM Fasta, JSON
DRAK2.AA Protein Sugen 372 None Fasta, JSON
DRAK2.NA RNA Sugen 3298 None Fasta, JSON

Protein domain

Protein domains of DRAK2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase DRAK2.AA DAPK 35-293 62 3e-241 672.66 In-house 1-264 (264) Show / Hide 
Range on Protein: 35-293
Range on HMM: 1-264/264
Sequence Identity: 62% (165 aa)

TPKELGRGKFAVVRQCISKSTGQEYAAKSLKKRRRGQD----CRAEILHEIAVLELARSCPHVINLHEVYENATEIILVLEYAAGGEIFNLCLPELAEMV
...|||||.|||||.|..||||..|||| .|||||||.    ||.||.||||.||..|..|.|||||||||..|..||.|||..|||.|..|.....|..
MGEELGRGQFAVVRKCRHKSTGKHYAAKFIKKRRRGQSRRGVCREEIEHEIAILEECRGHPNVINLHEVYETRTDVILILEYVSGGELFDYCCEDREECL

SENDVIRLIKQILEGVHYLHQNNIVHLDLKPQNILLSS-IYPLGDIKIVDFGMSRKIGNASELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLL
.|.|..|..|||||||||||..||.|||||||||.|.. ..|.|||||.|||.||||.|..|.|.|||||||.||||.||.|...|||||.||.|.|..|
CEEDATRFMKQILEGVHYLHSRNICHLDLKPQNIMLTDRNIPQGDIKIIDFGLSRKICNGEEFRDIMGTPEYVAPEIVNYEPLSLATDMWSIGVITYIML

THTSPFVGEDNQETYLNISQVNVDYSEEMFSSVSQLATDFIQSLLVKNPEKRPTAESCLSHSWL
...|||.|...|||.|||||||.|.|||.||..|..|.|||..||||.||||.|||.||.|.|.
SGISPFLGDTKQETFLNISQVNYDFSEEYFSCTSEHAKDFIRRLLVKDPEKRMTAEECLQHPWI
Kinase DRAK2.AA DRAK 35-293 71 2.1e-218 686.19 In-house 1-259 (259) Show / Hide 
Range on Protein: 35-293
Range on HMM: 1-259/259
Sequence Identity: 71% (186 aa)

TPKELGRGKFAVVRQCISKSTGQEYAAKSLKKRRRGQDCRAEILHEIAVLELARSCPHVINLHEVYENATEIILVLEYAAGGEIFNLCLPELAEMVSEND
|.||.|||||||||.||.|.|||..|||..||||||||||.|||||||||.|...||.|||||||||...|.|||||||||||||..|.....|...|.|
TAKERGRGKFAVVRKCIHKNTGQHFAAKFMKKRRRGQDCRMEILHEIAVLMLCQDCPWVINLHEVYETRSEMILVLEYAAGGEIFQYCVADKEECFCEKD

VIRLIKQILEGVHYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDFGMSRKIGNASELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSP
|.|...|||||||||||.||||||||||||||.|.||..||||.||||||.|.|..|.|||||||.|.|||||||||||.|||||.||...|..|||.||
VQRCMRQILEGVHYLHQRNIVHLDLKPQNILLTSEYPEDDIKICDFGMSRYICNGEEVREIMGTPDYVAPEILNYDPITMATDMWSIGVLTYVMLTHISP

FVGEDNQETYLNISQVNVDYSEEMFSSVSQLATDFIQSLLVKNPEKRPTAESCLSHSWL
|||.|.|||.|||||.|.||||||||..|..|.||||||.|..||.|.|||.||.|.||
FVGDDKQETFLNISQCNLDYSEEMFSCHSPVAIDFIQSLCVIKPEDRMTAEECLDHPWL
Kinase DRAK2.AA MLCK 32-293 42 3.1e-124 329.24 In-house 1-257 (257) Show / Hide 
Range on Protein: 32-293
Range on HMM: 1-257/257
Sequence Identity: 42% (113 aa)

YTLTPKELGRGKFAVVRQCISKSTGQEYAAKSLKKRRRGQDCRAEILHEIAVLELARSCPHVINLHEVYENATEIILVLEYAAGGEIFNLCLPELAEMVS
|  . .||||||| .|. || ||||...|||  | |..    ......|| ..   .  | .|..|. .|. .|.....||  |||.|   . |  .. .
YQIH-EELGRGKFGIVHRCIEKSTGKTWAAKFIKCRKPKD--KENVKNEIEIMNQLH-HPNLIQCHDAFETKNEMVMIMEYISGGELFERIVDEDFHL-T

ENDVIRLIKQILEGVHYLHQNNIVHLDLKPQNILLSS---IYPLGDIKIVDFGMSRKIGNASE-LREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYM
| .||. ..||.||||..|..|||||||||.||.. .   .    .|||.|||  ||. .. . ..   ||||..|||. ||||....|||| .| |.||
EREVIHYMRQICEGVHHMHWQNIVHLDLKPENIMCQTRTSH----QIKIIDFGLARKYDPDEKKVKVMFGTPEFVAPEVVNYDPVGFQTDMWSVGVICYM

LLTHTSPFVGEDNQETYLNISQVNVDYSEEMFSSVSQLATDFIQSLLVKNPEKRPTAESCLSHSWL
||.  ||| |....||. |.. .. |. .| |  .|. |.|||  ||||..|||.||. || | ||
LLSGLSPFMGDNDRETMNNVTSCEWDFDDECFDDISDEAKDFISRLLVKDKEKRMTAHECLQHPWL
Kinase DRAK2.AA DAPK 35-293 47 3.5e-121 351.28 In-house 3-264 (264) Show / Hide 
Range on Protein: 35-293
Range on HMM: 3-264/264
Sequence Identity: 47% (127 aa)

TPKELGRGKFAVVRQCISKSTGQEYAAKSLKKR-----RRGQDCRAEILHEIAVLELARSCPHVINLHEVYENATEIILVLEYAAGGEIFNLCLPELAEM
.  |.| | ||||. |  ||||.|||||  |||     |||  .| .|  |. .|.  |  | .| ||.||||.|...|.||  .||| |     .  | 
MGEEIGSGQFAVVKKCREKSTGKEYAAKFIKKRRYTASRRGV-SREDIEREVSILREIRGHPNIITLHDVYENKTDVVLILELVSGGELFDFLCEK--EC

VSENDVIRLIKQILEGVHYLHQNNIVHLDLKPQNI-LLSSIYPLGDIKIVDFGMSRKIGNASELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYML
..|      |||||.|||..|  .|.|.|||| || ||    |   |||.|||....|   .| ..|.||||. |||| || |   .|||| ||.| | |
LNEEEATQFIKQILDGVHHMHSKHICHFDLKPENIMLLDRNVPNPRIKIIDFGLAHRIEPGNEFKNIFGTPEFVAPEIVNYEPLGLETDMWSIGVITYIL

LTHTSPFVGEDNQETYLNISQVNVDYSEEMFSSVSQLATDFIQSLLVKNPEKRPTAESCLSHSWL
|   ||| |.  |||  ||. || ...|| |.. |..| |||  |||| |.|| | . || |.| 
LSGASPFLGDTKQETLANITAVNYHFDEEYFKNTSEHAKDFIRRLLVKDPKKRMTIQECLQHPWI
Kinase DRAK2.AA CAMK 38-293 23 3.6e-106 343.2 In-house 1-425 (425) Show / Hide 
Range on Protein: 38-293
Range on HMM: 1-425/425
Sequence Identity: 23% (99 aa)

ELGRGKFAVVRQCISKSTG------------QEYAAKSLKKRRRG--------------------------QDCRAEILHEIAVLELAR------SCPHV
.|||| |..|. || |.|.            |..|.| ..|..                            .  |.....||... . .      . |..
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

INLHEVYENAT-------------------EIILVL---EYAAGGEIFNLCLPELAEM-----------------VSENDVIRLIKQILEGVHYLHQNNI
|.|.||||...                   ....|.   ||. ||| |  ..  . |                  ..| .. |...||...|||.|..||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHLDLKPQNILLSSIYPL--------------GDIKIVDFGMSRKIGNAS------------------------ELREIMGTPEYLA-PEILNY------
||.|||| ||||.. ..               ..|||.|||...|.   .                         ...  ||||| | ||.||.      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------DPITTATDMWNIGIIAYMLLTHTSPFVGE-------------DNQETYLNISQVNVDYSEEMFSSVS--------------------QLATD
        .... ..||| .|.| |..|. ..|| |.             . .|.. .| . . |. ...|| .|                    | . |
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

FIQSLLVKNPEKRPTAESCLSHSWL
.|...|...||||.|.| ||.| |.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase DRAK2.AA Trio 32-293 37 3.8e-106 273.02 In-house 1-258 (258) Show / Hide 
Range on Protein: 32-293
Range on HMM: 1-258/258
Sequence Identity: 37% (99 aa)

YTLTPKELGRGKFAVVRQCISKSTGQEYAAKSLKKRRRGQDCRAEILHEIAVLELARSCPHVINLHEVYENATEIILVLEYAAGGEIFNLCLPELAEMVS
|| .  |.||| |.|||.|. |.|| . |||   .| ..   ..  .|| ..|  . . |.|. ||. ||  .  ||.|| . .||.   || .... ..
YTFQ-EEIGRGRFSVVRRCWHKATGRTCAAKFIPYRMMD---KEQVYHEYEMLQ-HLQHPCVCSLHDTYETPRHYILILELCDDGELLC-CLMRWGS-YC

ENDVIRLIKQILEGVHYLHQNNIVHLDLKPQNILLSSIYP-LGDIKIVDFGMSRKIGNA--SELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYML
| .|.  . |.||.|||||.. | |||.|| |...    .   .|||.|||   ..  .    . .  |.||  ||||.. .|.  .|| | || ..| .
ESEVKTYMWQMLEAVHYLHNCHILHLDIKPENMMMWHYNAGRPQIKICDFGDAQQLWPHKVEPQHHQYGNPEFMAPEIIQGNPVSYGTDIWSIGVLTYVM

LTHTSPFVGEDNQETYLNISQVNVDYSEEMFSSVSQLATDFIQSLLVKNPEKRPTAESCLSHSWL
|.  |||..|. .|| .||  .... .|..| .||| |..||...|.  | |||.|..||.| |.
LSGISPFYDESDRETCMNICRGDFSFPECYFCHVSQNAKHFICKVLQEDPWKRPCASECLQHPWF
Kinase DRAK2.AA S_TKc 33-293 28 3.5e-81 276.94 SMART 1-231 (231) Show / Hide 
Range on Protein: 33-293
Range on HMM: 1-231/231
Sequence Identity: 28% (79 aa)

TLTPKELGRGKFAVVRQCISKSTGQEYAAKSLKKRRRGQDCRAEILHEIAVLELARSCPHVINLHEVYENATEIILVLEYAAG--GEIFNLCLPELA---
    ...|.| |..|..|. |.||...| | .|           |. ||..|.    .|....|..|... ... .|.||. |  |. | .         
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

-EMVSENDVIRLIKQILEGVHYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDFGMSRKIGNASELREIMGTPEYLAPEILNYDPITT-ATDMWNIGIIA
    .| .. ....||.... |.|...|.| ||||.||||..      ||| |||..|..      . . |||.|.|||.|   . .. . |.| .|.| 
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

YMLLTHTSPFVGEDNQETYLNISQVNVDYSEEMFSSVSQLATDFIQSLLVKNPEKRPTAESCLS-------HSWL
| .|.   ||    .... ...               |. | |||. .|.|.|||||||  .|        | |.
YEMLCGYPPFP---QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase DRAK2.AA Ciliate-E2a 32-293 32 9.4e-80 234.43 In-house 1-275 (275) Show / Hide 
Range on Protein: 32-293
Range on HMM: 1-275/275
Sequence Identity: 32% (92 aa)

YTLTPKELGRGKFAVVRQCISKSTGQEYAAKSLKKRRRGQD-CRAEILHEIAVL-ELARSCPHVINLHEVYENATEIILVLEYAAGGEIF-----NLCLP
| .. |..| |.|..|.    | ||...|.| ..|. . |.  ....  ||. . .|  . |..| |.||||. . . ||.||  ||| .     . .. 
YKFI-KKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQL--DHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFF

ELAEMVSENDVIRLIKQIL-EGVHYLHQNNIVHLDLKPQNILLS--SIY--PLGDIKIVDFGMSRKI-GNASE-LREIMGTPEYLAPEILNYDPI-----
|      .... ....|.| .|.||.||.||.| ||||.|||.   |    .. ||||.|||....| ..  . .  . ||| |.|||.||.  .     
EE-----IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQ

-TTATDMWNIGIIAYMLLTHTSPFVGEDNQETYLNISQVNVDYSEEM-FSSVSQLATDFIQSLLVKNPEKRPTAESCLSHSWL
 .|  ||| .|.| | ||....|| |.. .|.  .. . . |..    .. .|. . |... .|.|.|.||.||. .| | | 
YDTKCDMWSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase DRAK2.AA Pkinase 32-293 28 2.4e-74 258.1 Pfam 1-293 (293) Show / Hide 
Range on Protein: 32-293
Range on HMM: 1-293/293
Sequence Identity: 28% (86 aa)

YTLTPKELGRGKFAVVRQCISKSTGQEYAAKSLKKRRRGQDCRAEILH--EIAVLELARSCPHVINLHEVYENATEIILVLEYAAGG----EIF----NL
|..  . .|.| |..|..|. |.||...| | .|||..  ... . ..  ||...    ..|... |....|. ..| .|.||. ||    . |      
YHIG-RKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST-

CLPELAEMV--SENDVIRLIKQILEGVHYLHQNNIVHLDLKPQNILLS-SIYPLGDIKIVDFGMSRK--IGNASELREIMGTPEYLAPEILN-YDPITTA
   .    .  ||..... ..|||.|. |.|...|.| ||||.|||..   ..  ..|| ||| ...  . | | .  . |||.|.|||... . .....
---WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPK

TDMWNIGIIAYMLLTHTSPFVGE------DNQETYLNISQVNVDYSEEMFSSVS-----------------QLATDFIQSLLVKNPEKRPTAESCLSHSW
 ||| .|.| | .|.   || |.      | .. . .| .  ......  .|.|                 . . ||| ..| |.|.|||||| .| | |
VDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPW

L
.
F
Kinase DRAK2.AA Ciliate-E2 33-293 21 7.2e-68 231.79 In-house 1-365 (365) Show / Hide 
Range on Protein: 33-293
Range on HMM: 1-365/365
Sequence Identity: 21% (84 aa)

TLTPKELGRGKFAVVRQCISKSTGQEY------------------AAKSLKKRRRGQDCRAEILHEIAVLELARS---------------CPHVINLHEV
    | .|.| |..|..|  .......                  ..|   . .  ..   .|. || ..   ..               .|..|...|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YE--NATEIILVLEYAAGGEIFN------LCLPELAE---MVSENDVIRLIKQILE---------------GVHYLHQNN-IVHLDLKPQNILLSSIYPL
..  . . | ||.||. ||. |       .. ..  |     .|. .....||||.               ...|||..| |.| |.||.|||.      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

GDIKIVDFGMSRKIG-------------NASELRE--------------------IMGTPEYLAPEILNYDP---------ITTATDMWNIGIIAYMLLT
  |||.|||.|.|.              .  . .                     | |||.|.||||||. .          ... |.| .|.| |..|.
--IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF

HTSPFVGEDNQETYLNISQVNVDYSEE--------------MFSSVSQLATDFIQS----LLVKNPEKRPT-AESCLSHSWL
   ||        . .| | ..|....               . ..|| . |.|.     .|.|.||||.| .| .| | |.
GKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase DRAK2.AA CAMKL 32-293 28 3.6e-67 213.37 In-house 1-297 (297) Show / Hide 
Range on Protein: 32-293
Range on HMM: 1-297/297
Sequence Identity: 28% (87 aa)

YTLTPKELGRGKFAVVRQCIS-KSTGQEYAAKSLKKRRRGQDCRAE-------------ILHEIAVLELAR--SCPHVINLHEVY-------ENATEIIL
|.. . .||.| |..|. ..  . ||...| | ..|..   |. ..             |  ||. ... .    |..| |.||.       |. ..| |
YRIGK-TLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIET-KKIYL

VLEYAAGGE--IFNLCLPELAEM--VSENDVIRLIKQILEGVHYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDFGMSRKIGN-----ASELREIMGTP
|.||. |||   |.    .       .|..  |. .||...|.|.|...||| |.|| ||||..      |||.|||.| .. .        |..  |.|
VMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSP

EYLAPEILNY--DPIT-TATDMWNIGIIAYMLLTHTSPFVGEDN------QETYLNISQVNVDYSEEMFSSVSQLATDFIQSLLVKNPEKRPTAESCLSH
.| ||||..   .|    ..|.| .|.| |.... . || ....         ||   .    | .  ...||  . |.|...|..|||||||..  ..|
PYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNH

SWL
 |.
PWM
Kinase DRAK2.AA CAMK1 131-293 37 1.2e-65 189.79 In-house 106-276 (276) Show / Hide 
Range on Protein: 131-293
Range on HMM: 106-276/276
Sequence Identity: 37% (64 aa)

SENDVIRLIKQILEGVHYLHQNNIVHLDLKPQNILLSSIYPLGDIK--IVDFGMSRKIGNAS-ELREIMGTPEYLAPEILNY---DPITTATDMWNIGII
.|.|  ...||||. |.|.|...||| ||||.|.|......  .||  | ||| |..... .  .    |||.| |||.|..   .|   | ||| ||.|
TEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDMWSIGVI

AYMLLTHTSPFVGED-NQETYLNISQVNVDYSEEMFSSVSQL-ATDFIQSLLVKNPEKRPTAESCLSHSWL
 | ||.  .|| .|. ..| .  |.   ... .  . ..|   | |||  .|...|.||.|.| || | |.
TYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase DRAK2.AA CAMK1 32-119 30 1.6e-29 82.91 In-house 1-96 (276) Show / Hide 
Range on Protein: 32-119
Range on HMM: 1-96/276
Sequence Identity: 30% (30 aa)

YTLTPKELGRGKFAVVRQCISKST---GQEYAAKSLK-KRRRGQDCR---AEILHEIAVLEL--ARSCPHVINLHEVYENATEIILVLEYAAGGEIF
| .. ||.||| |..|..|. |.|   |..|| | .. |.   .. .   . .. ||...      ..|..|...|.||  ... ||.|.  |||.|
YEFG-KEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELF
Kinase DRAK2.AA TyrKc 33-293 21 4.2e-14 5.42 SMART 1-280 (280) Show / Hide 
Range on Protein: 33-293
Range on HMM: 1-280/280
Sequence Identity: 21% (65 aa)

TLTPKELGRGKFAVVRQCISKSTGQEYAAKSLKKRRRGQDCRAEILHEIAVLELA-RSCPHVINLHEVYENA-------TEIILVLEYAAGGEIFNLCLP
    |.||.| | .|.... |   .. | |.||.       |.....|. ..     . |....|. |             . .|.||...|   .  | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGD-LKDYLR

ELAEMVSENDVIRLIKQILEGVHYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDFGMSRKIGNA------SELREIMG--TPE------YLAPEILNYD
.  . ..  | .    || .|  |||..|..| ||   |.|... .    .|| |||.||.|..       ..    ..            .||| .|| 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

PITTATDMWNIGIIAYMLLTHTSPFVGE------DNQETYLNISQVNVDYSEEM-----FSSVSQLATDFIQSLLVK----NPEKRPTAESCLSHSWL
  ||..| |  |.  . ..|   .   .      .||| . .. | .     .      |      ..| . ..  .    .||.||| . .  |. .
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF----VCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase DRAK2.AA Pkinase_Tyr 32-186 26 1.3e-09 33.23 Pfam 1-161 (270) Show / Hide 
Range on Protein: 32-186
Range on HMM: 1-161/270
Sequence Identity: 26% (45 aa)

YTLTPKELGRGKFAVVRQCISK----STGQEYAAKSLKKRRRGQD-CRAEILHEIAVLELARSCPHVINLHEVYE-----NATEIILVLEYAAGGEIFNL
 |.  |.||.| | .|.... |    .|... | |.||     .. ||.. ..|....    ..|....|. |       |  .|..|.||...|     
ITFG-KKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN--QIYIVMEYMPHG-DLLD

CLPEL---AEMVSENDVIRLIKQILEGVHYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDFGMSRKI
 | .     . ..  | .    || .|  ||...|..| ||   |.|...  ..  .|| |||..| |
YLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE--NN-VVKICDFGLARDI