Gene LMR3 (Mouse)
LMR3
Sequence
Protein domains of LMR3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | LMR3.AA | Lmr | 133-411 | 66 | 3.4e-228 | 764.36 | In-house | 1-283 (283) | Show / Hide |
Range on Protein: 133-411 Range on HMM: 1-283/283 Sequence Identity: 66% (188 aa) LSYLQEIGSGWFGKVILGEVFS---DYSPAQVVVKELRASAGPLEQRKFISEAQPYRSLQHPNVLQCLGVCVETLPFLLIMEFCQLGDLKRYLRAQRPPE |.|.||||.||||||.||||.| ..|.||||||||||||.|.||..|..|.||||.|||||||||||.||||.|.||.||||..||||.|||..||.| LNYIQEIGNGWFGKVLLGEVHSLHPGMSKAQVVVKELRASASPQEQMQFLQEVQPYRELQHPNVLQCLGQCVETIPYLLVMEFCPYGDLKNYLRKCRPME GMSPELPPRDLRTLQRMGLEIARGLAHLHSHNYVHSDLALRNCLLTSDLTVRIGDYGLAHSNYKEDYYLTPER-LWVPLRWAAPELLGELHGSFVLVDQS .|.|..|||...|||||..|||.||||.|.|..||||||||||.|..||||.||||||||..||||||.|... .||||||.||||..|.|.....|||. HMMPDKPPRQTMTLQRMACEIACGLAHMHQHHFVHSDLALRNCQLCADLTVKIGDYGLAHCQYKEDYYITKDQCHWVPLRWIAPELMDEFHQNLLVVDQT RESNVWSLGVTLWELFEFGAQPYRHLSDEEVLAFVVRQQHVKLARPRLKLPYADYWYDILQSCWRPPAQRPSASDLQLQLTYL ..||.||||||.||||||.||||.|.|||.|||.|||.|..||..|.|.|||.|.||.|.|.||..|.|||.|.|....|||| KYSNIWSLGVTMWELFEFAAQPYPHHSDEQVLAQVVREQDIKLPKPQLQLPYSDRWYEIMQFCWMQPDQRPTAEDVHRLLTYL |
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Kinase | LMR3.AA | TK | 133-408 | 19 | 3.7e-89 | 298.96 | In-house | 1-486 (486) | Show / Hide |
Range on Protein: 133-408 Range on HMM: 1-486/486 Sequence Identity: 19% (95 aa) LSYLQEIGSGWFG---KVILGEVFS-----------------------DYSPAQVVVKELR--ASAGPLEQRK--------------FISEAQPYRS--L . .....|.|.|| .| .||... . . .| || |. ... . |.. . .|.. .. . ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG QHPNVLQCLGVCVET------------LPFLLIMEFCQLGD----LKRYLRAQRPPEGM----------------------------------------- .|||.....|||.. |....||....|| |. |||. ||.. HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY --------SPELPPRDLRTLQR----------------MGLEIARGLAHLHSH------NYVHSDLALRNCLLTSDLT-----------VRIGDYG---- .|.|. .|| ... | . ||.|...|||. |.|| ||| ||||...... ..|.|.| DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ ----LAHSNYKEDYYLTPE------------------------RLWVPLRWAAPELLGELHGSFV--LVDQSRESNVWSLGVTLWELFEFG-AQPYRHLS || |..|.| . . . ..|.|| ||| | . . | . .| |||.||..||.| .| ...| .| GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS D---------EEVLAFVVR----------QQHVKLARPRLKLPYA-------------DYWYDILQSCWRP-PAQRPSASDLQLQL . .||. ...| .. .. .|. .. . .||..|.||.. |..||. |.|. || NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL |
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Kinase | LMR3.AA | Pkinase_Tyr | 133-408 | 32 | 2.4e-77 | 262.59 | Pfam | 1-270 (270) | Show / Hide |
Range on Protein: 133-408 Range on HMM: 1-270/270 Sequence Identity: 32% (95 aa) LSYLQEIGSGWFGKVILGEVF--SDYSPAQVVVKELRASAGPLE--QRKFISEAQPYRSL-QHPNVLQCLGVCV-ETLP--FLLIMEFCQLGDLKRYLRA .. ....|.| ||.| .|. . | .| || |. .| . . ...|..||. ..| .|||.....|||. . | ...||....|||. |||. ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK QRPPEGMSPELPPRDLRTLQRMGLEIARGLAHLHSHNYVHSDLALRNCLLTSDLTVRIGDYGLAHSNYKEDYY-LTPERLWVPLRWAAPELLGELHGSFV .| .. .| .. .| | ..||.|...|.|.|..| ||| ||||.|....|.|.| ||| |..||| . . .| .| ||| . . HR------EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK---- LVDQSRESNVWSLGVTLWELFEFGAQP-YRHLSDEEVLAFVVRQQHVKLARPRLKLPY--ADYWYDILQSCW-RPPAQRPSASDLQLQL . .| ||| ||..||.| .|.|| | .|.|||.... .. . |.. | | ||....|| |..||. |... || ---FTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYED------GYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL |
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Kinase | LMR3.AA | TyrKc | 133-408 | 31 | 4.1e-73 | 250.14 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 133-408 Range on HMM: 1-280/280 Sequence Identity: 31% (96 aa) LSYLQEIGSGWFGKVILGEVFSDYSPAQVVVKELRASAGPLEQRKFISEAQPYRSL--QHPNVLQCLGVCVET-------LPFLLIMEFCQLGDLKRYLR .. ....|.| ||.| .|. || || |...| .. |..||. ..| .|||.....|||.. | ...||.. .|||| ||| ITLGKKLGEGAFGEVYKGTWK-----IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR AQRPPEGMSPELPPRDLRTLQRMGLEIARGLAHLHSHNYVHSDLALRNCLLTSDLTVRIGDYGLAHSNYKE-------DYYLT----PERLWVPLRWAAP . || ...| . . ||.| ..|||.|..| ||| ||||.....||.|.| ||. | . ||| . .. ..|.|| || KHRPK---------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAP ELLGELHGSFVLVDQSRESNVWSLGVTLWELFEFGAQPYRH-----LSDEEVLAFVVRQQHVKLARPRLKLP-----YADYWYDILQSCWRP-PAQRPSA | . .| | . .| ||| ||..||.| .|.||| .|..||...| . . .| .| | |.| ..||. |..||. ECI--NYGKF-----TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGY--RMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTF SDLQLQL |.. .. SEIHECF |
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Kinase | LMR3.AA | UTK | 133-408 | 27 | 7.5e-70 | 238.13 | In-house | 1-296 (296) | Show / Hide |
Range on Protein: 133-408 Range on HMM: 1-296/296 Sequence Identity: 27% (85 aa) LSYLQEIGSGWFGKVILGEVFSDY---SPAQVVVKELR-ASAGPLEQR---KFISEAQ---PYRSLQ-HPNVLQCLGVCVETLPFLLIMEFCQLGDLKRY . ....|.| || | .... . ..| ||... .... |.. .|. ||. . .. |||||. .|||. |.....|... ||| | VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY LRAQRPPEGMSPELPPRDLRTLQRMGLEIARGLAHLHSHNYVHSDLALRNCLLTSD-------LTVRIGDYG---LAHSNYK--------EDYYLTPE-R || .|| . .. .|... | . ||||...|||...|| ||| ||||.... ....|.|.| ... . |.|| .. . LRRHRPTPP--ACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQ LWVPLRWAAPELLGELHGSFVLVDQSRESNVWSLGVTLWELFEFGAQPYRHLSDEEVLAFVVRQQHVKLARPRLKLPYADYWYDILQSCWRP-PAQRPSA .|.|| ||| | . . .. | |||.||..||.. .|..|| ..|...|...|... . ...|. . |.....||.. |. ||.. DRWPIRWMAPEALTHHT------RFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPW---DCPHPVYRLMHRCWHYDPQERPDF SDLQLQL || |. EDLVQQM |
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Kinase | LMR3.AA | TK-Unique | 133-360 | 33 | 6.9e-59 | 201.65 | In-house | 1-249 (294) | Show / Hide |
Range on Protein: 133-360 Range on HMM: 1-249/294 Sequence Identity: 33% (85 aa) LSYLQEIGSGWFGKVILGEVFS----DYSPAQVVVKELRASAGPLEQRKFISEAQPYRSLQ-HPNVLQCLGVCVETL-PFLLIMEFCQLGDLKRYLRAQR | ...||.| || |. |||.. . . .|.|| |...| ......| .|.| ...| |||..||||.|... |...|||.|. |.| ||| | LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR P------------------PEGMSPE-LPPRDLRTLQRMGLEIARGLAHLHS--HNYVHSDLALRNCLLTSDLTVRIGDYGLAHSNYKEDYYLTP-ERLW | |.....| . |.|| . . .||.|...|.| .. || ||. ||.|||.|... |.|.|.| |.. | . .. PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYH---FAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGR VPLRWAAPELLGELHGSFVLVDQ-SRESNVWSLGVTLWELFEFGAQPYRHLSDEEVL .|.|| ||| | . . .|.|||.||..||.| .||.||. ....... IPIRWMAPESLKCY-----HGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIM |
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Kinase | LMR3.AA | InsR | 133-410 | 33 | 5.3e-58 | 193.38 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 133-410 Range on HMM: 1-278/278 Sequence Identity: 33% (98 aa) LSYLQEIGSGWFGKVILG---EVFSDYSPA--QVVVKELRASAGPLEQRKFISEAQPYRSLQHPNVLQCLGVCVETLPFLLIMEFCQLGDLKRYLRAQRP . ..| | | ||.| .| . .| . .. .| . ..| | | .|| . .| |||| | . .||. ..|||| |||. || IVLIRECGQGSFGMVYEGIAKGIVPDEEWRFGRCAIKTVNENASMRERIEFLNEASVMKEFNCHHVVRLLGVCSRGQPMYVVMEMMTYGDLKSYLRSRRP PEG-MSPELP----PRDLRTLQRMGLEIARGLAHLHSHNYVHSDLALRNCLLTSDLTVRIGDYGLAHSNYKEDYYLTPERLWVPLRWAAPELLGELHGSF |. | .. . | . | ||. |.| | . ..|| ||| |||. |.|| ||| |.. | ||| . | || ||| | . | | EEEFNNPGCNRNQHVPCLDQMHQMAAEICDGMAYLAAKKFVHRDLACRNCMVNHDFTVKIGDFGMTRDIYEHDYYRKGGKGMLPVRWMAPESLKD--GVF VLVDQSRESNVWSLGVTLWELFEFGAQPYRHLSDEEVLAFVVRQQHVKLARPRLKLPYA--DYWYDILQSCWRP-PAQRPSASDLQLQLTY . | |||.|| ||| .|.||| || |.|| .. . | |. | .||... . ||. | ||.. |. | -----TTHSDVWSFGVVLWEMVTLGEQPYQGLSNEQVLKYIGMDGNV------LRPPENCPEYWQELMMMCWQYQPKMRPTFLDIIHYLCD |
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Kinase | LMR3.AA | Trk | 133-408 | 32 | 7.2e-51 | 170.64 | In-house | 1-275 (275) | Show / Hide |
Range on Protein: 133-408 Range on HMM: 1-275/275 Sequence Identity: 32% (94 aa) LSYLQEIGSGWFGKVILGE---VFSDYSPAQVVVKELRASAGPLEQRKFISEAQPYRSLQHPNVLQCLGVCVETLPFLLIMEFCQLGDLKRYLRAQRPPE . .|.| | ||||.|.| . . | || |. . . | ||. |||... . |||.. |.|.. |. . |||..|||.. | IVLKWELGEGAFGKVFLAECYNLCPEQDKMMVAVKTLKDASE-NARKDFQREAELLTNLQHQHIVKFYGVCTDHDPLLMVFEYMKHGDLNKYLRQHGPDA GMSPELPP------RDLRTLQRMGLEIARGLAHLHSHNYVHSDLALRNCLLTSDLTVRIGDYGLAHSNYK-EDYYLTPERLWVPLRWAAPELLGELHGSF . . .| . . .|| |. . | .|| |.| |||| .| |.|||.|. | ||| . | || || | MCYAQYQPRQAPGPLTIDQMLWIAKQIASGMVYMASQHFVHRDMATRNCLVGQNLIVKIGDFGMSRDVYSHTDYYRVGHHTMLPIRWMPPE-------SI VLVDQSRESNVWSLGVTLWELFEFGAQPYRHLSDEEVLAFVVRQQHVKLARPRLKLPYADYWYDILQSCW-RPPAQRPSASDLQLQL . . || |||.||..|| |..| ||. || || .. | ..| ||| . | |||. || | | || .. |. . MYRKFTYESDVWSFGVVMWECFTYGKQPWYQLSNHEVIECIH-QGRHRLERPR-RCPQE--VYDIMLGCWQREPQQRMNIKDIHDII |
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Kinase | LMR3.AA | DDR | 133-408 | 28 | 4.3e-44 | 151.62 | In-house | 1-306 (306) | Show / Hide |
Range on Protein: 133-408 Range on HMM: 1-306/306 Sequence Identity: 28% (91 aa) LSYLQEIGSGWFGKVILGEVFSDY------SPAQ--------VVVKELRASAGPLEQRKFISEAQPYRSLQ-HPNVLQCLGVCVETLPFLLIMEFCQL-G | . ||.| || | | ||.. .. . | || ||. | . | .|. .. |||. .|||.. | ..|||. | LIFVEKIGEGQFGEVHLCEVEGMQDYIEFDFHCDVHKGHPTLVAVKMLRPDACKHARNDFHKEIKCMSQCKRHPNIVRLVGVCTQDEPYCMIMEYMENLG DLKRYLRAQRPPEGMSPELP---------PRDLRTLQRMGLEIARGLAHLHSHNYVHSDLALRNCLLTSDLTVRIGDYG--LAHSNYKEDYYLTPE---- ||. .. .. ... . ... . . ... || |...| | | || ||| |||| .....| | | .. . | ||| DLNQFWMEHEAENSGLMNCKADTQNCQKPTISYECCVYICTQIASGMKYLESMNFVHRDLATRNCLVGKEYHIKICDFGTVMSRNLYSQDYYRVEGFTGR -RLWVPLRWAAPELLGELHGSFVLVDQSRESNVWSLGVTLWELFEFG-AQPYRHLSDEEV-----LAFVVRQQHVKLARPRLKLPYADYWY-DILQSCWR | |.|| |.| | .| . | ||. |||.|| | | .||| .|.|| | . | .| |..|.. . | . . .||| QRHHMPIRWMAWE-------SILLGKFTTKSDVWAFGVTMWEMFMFCREQPYEQLTDEQVIENACEFFRHQGMQVYLPMPPM---CPYEIYNQLMCRCWR P-PAQRPSASDLQLQL . |||| . . . | RDQSQRPSFEEIHKFL |
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Kinase | LMR3.AA | CTKA | 133-408 | 33 | 2.3e-42 | 140.09 | In-house | 1-290 (290) | Show / Hide |
Range on Protein: 133-408 Range on HMM: 1-290/290 Sequence Identity: 33% (101 aa) LSYLQEIGSGWFGKVILGEVFSDYS--------PAQVVVKELRASAGPLEQRKFISEAQPYRS---LQHPNVLQCLGVCVETLPFLLIMEFCQLGDLKRY . .||.| .| | | | || |.. | . | | || .| . ||||| |||| | . |||. |.|||. | HCIMFKIGEGHYGQVFRAWLMPDPDDFKAQRKKGKDVAVKMLKDHATEEDRRAFLHEAF-VLSSEHFHHPNVLRLLGVCTQHKPWHMIMEHMQYGDLHCY LRAQRPPE----------GMSPELPPRDLRTLQR--MGLEIARGLAHLHSHNYVHSDLALRNCLLTSDLTVRIGDYGLAHSNYKE-DYYLTPERLWVPLR ||| || . | ... | .|| | | . || ||| ||||| . .. | | |.. | || . | | LRACRPADGQVCPARARRSIPRSFHPIEVHAHEQVYMAMQIAAGMNYLAEMGFVHRDLACRNCLLGQYCHIKIADFGHGRTLRTESQYYYVSSQRVMPVR WAAPELLGELHGSFVLVDQSRESNVWSLGVTLWELFEFGAQPYRHLSDEEVLAFVVRQQHVKLAR--PRLKLPY--ADYWYDILQSCWRP-PAQRPSASD | ||| | . | | | | ||. || |||.. .| |.||.|| || . .. ||..| .. | | ||.. |.|||. WMAPEALCF--GKF-----SCASDVWAFGVLLWEIMSMGEKPWRHMSDQEVCQAY-------TSHGMRRLPVPRNCPQVLYHCMQECWKFEPNQRPTFET LQLQL || | LQRML |
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Kinase | LMR3.AA | Musk | 133-363 | 32 | 3e-42 | 137.28 | In-house | 1-241 (282) | Show / Hide |
Range on Protein: 133-363 Range on HMM: 1-241/282 Sequence Identity: 32% (81 aa) LSYLQEIGSGWFGKVILG---EVFSDYSPAQVVVKELRASAGPLEQRKFISEAQPYRSLQHPNVLQCLGVCVETLPFLLIMEFCQLGDLKRYLRAQRPPE | ..|| | || | . | || |.. | | | ||. |||. . |||| | | .|. ||| .|.. | IIYVRDIGEGAFGRVFQARAPGLVPYEEETMVAVKMLKDDASKQMQMDFQREACMMAEFDHPNIVKLLGVCFVGRPMCLLFEYMAYGDLNEFLHSCSPHR GMSPELPPR------------DLRTLQR--MGLEIARGLAHLHSHNYVHSDLALRNCLLTSDLTVRIGDYGLAHSNYKEDYYLTPERLWVPLRWAAPELL | | |... . | .|| |.| | .|| ||| |||| . |.| |.||.. | .||| | .| || .|| . TCSRTHQDRGMRAQVSSPGPPQLKCYHQLCMAKQIACGMAYLSEMMFVHRDLATRNCLINEHMDVKIADFGLSRYIYHQDYYKGHENDHIPIRWMPPESI GELHGSFVLVDQSRESNVWSLGVTLWELFEFGAQPYRHLSDEEVLAFV . | . || ||. || |||.| .. ||| .. |||. .. --WYNQFTY-----ESDVWAYGVCLWEIFSYALQPYYGMTHEEVIYYI |
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Kinase | LMR3.AA | S_TKc | 133-411 | 19 | 2.7e-30 | 107.88 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 133-411 Range on HMM: 1-231/231 Sequence Identity: 19% (56 aa) LSYLQEIGSGWFGKVILGEVFSDYSPAQVVVKELRASAGPLEQRKFISEAQPYRSLQHPNVLQCLGVCVETLPFLLIMEFCQL--GDLKRYLRAQRPP-- |..||.| |||| .. . . .| .|... .....| | .. .|||. ....|... . ..||.| |||..|.. .... YEILRKIGKGAFGKVYKCRHKK--TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL -EGMSPELPPRDLRTLQRMGLEIARGLAHLHSHNYVHSDLALRNCLLTSDLTVRIGDYGLAHSNYKEDYYLTPERLWVPLRWAAPELLGELHGSFVLVDQ .... ... .|...|...|||. .| || | ||.. .. |.| ||| . . . . |||.| RFPFPE-H-------ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL----------GY SR-ESNVWSLGVTLWELFEFGAQPYRHLSDEEVLAFVVRQQHVKLARPRLKLPYADYWYDILQSCWR-PPAQRPSASDLQL------QLTYL .. .. .||.|..|.|.. | |.. ..... ... . |... |.. |..||.| .. . .. GKCKCDWWSCGCILYEMLC-GYPPFP---QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | LMR3.AA | Pkinase | 133-408 | 18 | 1.9e-25 | 91.04 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 133-408 Range on HMM: 1-293/293 Sequence Identity: 18% (58 aa) LSYLQEIGSGWFGKVILGEVFSDYSPAQVVVKELRAS-AGPLEQRKFIS--EAQPYRSLQHPNVLQCLGVCVETLPFLLIMEFCQLG----DLKRYLRAQ . .. |||| ||.| .. .. .|.||... . . . ... . |.| ..|.|||........ . ..||.|. | ||..|... YHIGRKIGSGSFGCVYKCHHKGTGK--IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST- RPPEGMSPELPPR--DLRTLQRMGLEIARGLAHLHSHNYVHSDLALRNCLLTSDLTV----RIGDYGLA--HSNYKEDYYLTPERLWVP---LRWAAPEL . . . ...... ..|.|||...||.. .| || . |.|. .. .. .|.| ||| .. | . .... ....|||. -------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD------Y-NNS-MTTFCGTPWYMAPEV LGELHGSFVL--VDQSRESNVWSLGVTLWELFEFGAQPYRHL----SDEEVLAFVVRQQHVKLARPRLKLPY------------------ADYWYDILQS .. . .... .||.|..|.|.. | |... . . .. ..| . .| ... .. . |.. . --------IRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKW CWRP-PAQRPSASDLQLQ--L |... |..||.| .. . CLCKDPKKRPTAEQILQHPWF |
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Kinase | LMR3.AA | Ror | 250-351 | 44 | 2.1e-24 | 87.43 | In-house | 128-222 (308) | Show / Hide |
Range on Protein: 250-351 Range on HMM: 128-222/308 Sequence Identity: 44% (45 aa) IARGLAHLHSHNYVHSDLALRNCLLTSDLTVRIGDYGLAHSNYKEDYYLTPERLWVPLRWAAPELLGELHGSFVLVDQSRESNVWSLGVTLWELFEFGAQ || | | || .|| ||| |||| ..|.| | ||. | ||| . . | | || .|| . | | | .| .|| ||.||| . .| | IAAGMEYLSSHHFVHRDLAARNCLVGEHHHVKISDFGLMRDIYSSDYYRMQHKSWMPIRWMSPEAI--MYGKF-----SEDSDIWSFGVVLWEIWSYGMQ PY || PY |
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Kinase | LMR3.AA | Ror | 133-218 | 29 | 1.9e-14 | 53.95 | In-house | 1-89 (308) | Show / Hide |
Range on Protein: 133-218 Range on HMM: 1-89/308 Sequence Identity: 29% (26 aa) LSYLQEIGSGWFGKVILGEVFSDY---SPAQVVVKELRASAGPLEQRKFISEAQPYRSLQHPNVLQCLGVCVETLPFLLIMEFCQLGDL .. . |.| . |||| |. .. .. |..| .. | | .. | |.. .|.|||. |||| | . . |.. ||| VRFMEELGECQFGKVYKGHLMGPNFMYHCMAVAIKTCKHDASPAQWQDFRQEIMLMATLHHPNIVCLLGVCTMDQPYCMLFEYMNHGDL |
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Kinase | LMR3.AA | Musk | 385-408 | 28 | 0.007225 | 5.05 | In-house | 258-282 (282) | Show / Hide |
Range on Protein: 385-408 Range on HMM: 258-282/282 Sequence Identity: 28% (7 aa) YDILQSCW-RPPAQRPSASDLQLQL | .. || . || ||. ... . YQLMRRCWQKNPADRPFFCQIHHCI |
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Kinase | LMR3.AA | TK-Unique | 385-408 | 36 | 0.046199 | 3.05 | In-house | 270-294 (294) | Show / Hide |
Range on Protein: 385-408 Range on HMM: 270-294/294 Sequence Identity: 36% (9 aa) YDILQSCWRP-PAQRPSASDLQLQL | ...|||. | .||| ... .| YNLMKSCWQWEPEERPSFRQIKHRL |