Gene MISR2 (Mouse)

MISR2

Species: Mouse
Alias: Amhr2, MISR2
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: TKL
Family: STKR
Subfamily: STKR2

Sequence

Name Sequence Type Origin Length Description Download
MISR2.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 303 Kinase domain by global Sugen HMM Fasta, JSON
MISR2.AA Protein Sugen 568 None Fasta, JSON
MISR2.NA RNA Sugen 1947 None Fasta, JSON

Protein domain

Protein domains of MISR2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase MISR2.AA Type2 199-501 41 1.3e-196 654.92 In-house 1-315 (315) Show / Hide 
Range on Protein: 199-501
Range on HMM: 1-315/315
Sequence Identity: 41% (130 aa)

LRFSQVIQEGGHAVVWAGRLQGE-----MVAIKAFPPRAVAQFRAERAVYQLL-GLQHDHIVRFITAGQG--GPGPLPSGPLLVLELYPKGSLCHYLTQY
......|..|....||.......     .||.|.||.. ......|...|.|. ...|..|..||.|...  ..|.......||.|...|||||.||.|.
IQLMELIGKGRFGCVWKAQWHNNNGEKRTVAVKIFPEQDKQSWQNEKDIYSLPYHMWHENILQFICAEKRRVHMGDGWMEYWLVTEFHHKGSLCDYLKQH

TSDWGSSLRMALSLAEGLAFLHEERWQDGQ---YKPGIAHRDLSSQNVLIREDRSCAIGDLGLALVLPGLAQPPALAPTQPRGPAAILEAGTQRYMAPEL
|.||....|||.|.|.|||.||||.||..|   .||.|||||..|.|||...|..|.|.|.|||.....  ||....||.|.....| ..||.||||||.
TIDWHECCRMAMSMARGLAHLHEEIWQWCQTDHHKPPIAHRDIKSKNVLVKNDMTCCIADFGLAMRFCPGKQPYKWEPTMPGDTHNIGQVGTRRYMAPEV

LDKTLDLQDWGTALQRADVYSLALLLWEILSRCSDLRPDHRPPPFQLAYEAELGSN-PSACELWALAVEERKRPNIPSTWSCSATDPRGLRELLEDCWDA
|......||...|....|.|...|.|||..|||.|..||...|..|...|.|.|.. || .....|.|..||||..|..|.|.....|.|.|..|||||.
LEGAVNFQDCRDAFKQMDMYAMGLVLWEMVSRCTDHYPDDEVPEYQMPFEEEVGQHDPSFEDMQELVVRKRKRPQWPDHWKCHPGMQRMLCETIEDCWDH

DPEARLTAECVQQRL
|.||||||.|||.|.
DAEARLTAQCVQERM
Kinase MISR2.AA STKR 199-501 36 6.1e-173 562.9 In-house 1-312 (312) Show / Hide 
Range on Protein: 199-501
Range on HMM: 1-312/312
Sequence Identity: 36% (115 aa)

LRFSQVIQEGGHAVVWAGRLQG----EMVAIKAFPPRAVAQFRAERAVYQLLGLQHDHIVRFITAGQGGPGPLPSGPLLVLELYPKGSLCHYLTQYTSDW
... ..| .| .. || |...|    |.||.| ||.|  ... .|. .||. ...|..|..||.|.. ... . . ..|..|....||||.||...|.||
IQLIECIGKGRYGEVWKGKWRGNGEKETVAVKIFPSRDEQSWFRETEIYQTPMMRHENILQFIAADMKHTEGSWTQYWLITEYHENGSLCDYLKRHTIDW

GSSLRMALSLAEGLAFLHEERW--QDGQ-YKPGIAHRDLSSQNVLIREDRSCAIGDLGLALVLPGLAQPPALAPTQPRGPAAILEAGTQRYMAPELLDKT
 ...|||.|.|.|||.||.|.|  . .| .||.|||||. |.|.|...| .|.|.|.|||..... .... ...|. ...|.. . ||.||||||.||..
HEMCRMAHSMACGLAHLHMEIWGWGTQQHHKPAIAHRDIKSKNILVKNDGTCCIADFGLAMRHDPDTNQIDIHNTM-QDNAQNTQVGTKRYMAPEVLDGA

LDLQDWGTALQRADVYSLALLLWEILSRCSDLRP---DHRPPPFQLAYEAELGSNPSACELWALAVEERKRPNIPSTWSCSATDPRGLRELLEDCWDADP
...|.. .|..|.|.|...| .|||..||.|..|   |...|..|..........|| ..........|.|||||..|.|.....|......|.|||.||
MNFQCFESAFKRMDMYAMGLVMWEIARRCTDGGPDLVDQIVPEYQMPFYDWVPNHPSFEDMQKVVCRKRQRPNIPNRWKCNHPAMRSMCKTMEECWDHDP

EARLTAECVQQRL
||||||.||....
EARLTALCVKKTM
Kinase MISR2.AA TKL 205-501 24 5.5e-85 288.65 In-house 1-364 (364) Show / Hide 
Range on Protein: 205-501
Range on HMM: 1-364/364
Sequence Identity: 24% (92 aa)

IQEGGHAVVWAGRLQG----------EMVAIKAFPPRAV----------------------------AQFRAERAVYQLLGLQHDHIVRFITAGQGGPG-
| .|| ..|. |...|          . ||.| |. . .                            ..|. |. . ... |.|..||.|. . . .|. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-------PLPSGPLLVLELYPKGSLCHYLTQYTSDWGSSLRMALSLAEGLAFLHEERWQDGQYKPGIAHRDLSSQNVLIREDRS--------------CA
         .. . .| |..|.|||.|||.     |   .|.||. | |...|| .... .. ||.|.|||| |.|.|. |.                | 
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCT-KPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK

IGDLGLALVLPGLAQPPALAPTQP-------RGPAAILEAGTQRYMAPELLDKTLDLQDW---------GTALQRADVYSLALLLWEILSRCSDLRPDHR
|.|.||. .. .  .  . . |..       .. . . . || |.||||.|.........         ... ...|||| ...|||||.||        
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR-------

PPPFQ-LAYEAELGSNPSACELWALAVEERKRPNIPSTWSC------SATDPRGLRELLEDCWDADPEARLTAECVQQRL
  |.. . |. .... |   | .........|| ||..|..        . |.....|..||||.|||.|...... .||
--PYYDYPYMPMIFQDP-FEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase MISR2.AA Type1 199-501 33 5.2e-73 196.87 In-house 1-290 (290) Show / Hide 
Range on Protein: 199-501
Range on HMM: 1-290/290
Sequence Identity: 33% (101 aa)

LRFSQVIQEGGHAVVWAGRLQGEMVAIKAFPPRAVAQFRAERAVYQLLGLQHDHIVRFITAGQGGPGPLPSGPLLVLELYPKGSLCHYLTQYTSDWGSSL
..  ..|  |    || |. .|| ||.| |  |  . .  |. .||   . |. | .|| |   . |      .|. . ...|||  ||...| |  . |
IQMIECIGKGRYGEVWRGKWRGENVAVKIFFSRDERSWFRETEIYQTVMMRHENILGFIAADMKDNGSW-TQLWLITDYHEHGSLYDYLNRHTLDTQQML

RMALSLAEGLAFLHEERWQDG-QYKPGIAHRDLSSQNVLIREDRSCAIGDLGLALVLPGLAQPPALAPTQPRGPAAILEAGTQRYMAPELLDKTLDLQDW
|.|.|.| |||.|| |        || |||||. | |.... . .|.|.|||||.  .  ..   .. . ||        ||.||||||.|| |.. .. 
RLAYSCACGLAHLHMEIFGTQEFGKPAIAHRDIKSKNIMVKKNGQCCIADLGLAVRHQQDTDQIDIG-QNPR-------VGTKRYMAPEVLDETMNMNCF

GTALQRADVYSLALLLWEILSRCSDLRPDHRPPPFQLAYEAELGSNPSACELWALAVEERKRPNIPSTWSCSATDPRGLRELLEDCWDADPEARLTAECV
  . ..||.||..| .|||. ||..     .   .|| |     . ||  .  .    .. |||||. |. | .  |..  | ..|| . |.||.||  .
-ESYKMADIYSFGLVMWEIARRCEVGG---IVEDYQLPYYDWVPNDPSFEDMRKVVCVRKLRPNIPNRWQ-SHPCMRHMAKLMKECWYQNPHARHTALRI

QQRL
   |
KKTL
Kinase MISR2.AA Pkinase 199-501 18 2.2e-27 97.92 Pfam 1-293 (293) Show / Hide 
Range on Protein: 199-501
Range on HMM: 1-293/293
Sequence Identity: 18% (62 aa)

LRFSQVIQEGGHAVVWAGRLQGEM--VAIKAFPPRAVAQFRA-------ERAVYQLLGLQHDHIVRFITAGQGGPGPLPSGPLLVLELYPKG----SLCH
... ..| .|. ..|. .. .|.   ||.| .. |              | .. . |.  |..|||.. . .      .. . .|.|. ..|    .|..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN--HPNIVRLYDWFED-----KDHIYMVMEYCEGGLYVMDLFD

YLT---QYTS--DWGSSLRMALSLAEGLAFLHEERWQDGQYKPGIAHRDLSSQNVLIREDRSC----AIGDLGLALVLPGLAQPPALAPTQPRGPAAILE
|..   . .   ..    .... ...||...|..         || |||| ..|.|| ..  .     |.| ||| ..              ... .   
YISTWRHGCFYFSEWECKFYMYQILRGLEYCHSM---------GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-----------Y-NNS-MTTF

AGTQRYMAPELLDKTLDLQDWGTALQRADVYSLALLLWEILSRCSDLRPDHRPPPFQLAYEAELGSNPSACELWALAVEERKRPNIPSTWSCSATD----
.|| .|||||.      ...     ...|..|. ..|.| |..          |||.   ..  .. . ..... ..   ....  .. |.||  .    
CGTPWYMAPEV------IRGGQYYGPKVDMWSCGCILYEMLCGR---------PPFP---GHC-WHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFR

-----------PRGLRELLEDCWDADPEARLTAECVQQR--L
           .. .......|.. ||. |.|||.. |   .
HWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase MISR2.AA S_TKc 199-502 18 1.8e-20 75.25 SMART 1-231 (231) Show / Hide 
Range on Protein: 199-502
Range on HMM: 1-231/231
Sequence Identity: 18% (59 aa)

LRFSQVIQEGGHAVVWAGRLQG--EMVAIKAFPPRAVAQFRAERAVYQLLGLQHDHIVRFITAGQGGPGPLPSGPLLVLELYPK--GSLCHYLTQYTS--
 .. ..| .|. ..|. .|  .  . ||||  .     ..| |... .    .|..||... . |       .   .|.|. .   |.| .|. .. .  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK---HHPNIVKLYDVFQD------DHLYMVMEYCDGDLGDLFDYIKKRGRHG

-----DWGSSLRMALSLAEGLAFLHEERWQDGQYKPGIAHRDLSSQNVLIREDRSCAIGDLGLALVLPGLAQPPALAPTQPRGPAAILEAGTQRYMAPEL
     .     ...  ....|...|.        . || ||||  .|.|. |     |.| ||| .|                       ||  |||||.
LRFPFPE-HARFYMYQICCALEYCHS--------H-GIIHRDLKPENILLDE--HIKICDFGLARQL-------------------TTFCGTPWYMAPEV

LDKTLDLQDWGTALQ-RADVYSLALLLWEILSRCSDLRPDHRPPPFQLAYEAELGSNPSACELWALAVEERKRPNIPSTWSCSATDPRGLRELLEDCWDA
|               ..|..|.  .|.| |...   .        |. ..  .                                .. ...... |.. 
L----------GYGKCKCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG--------------------------------SPEAKDFIRKCLQK

DPEARLTAECVQ-------QRLA
||| |.|||. |           
DPEKRPTAEALQDEWDIKCHPWF
Kinase MISR2.AA TK 199-352 14 1.4e-15 47.95 In-house 1-305 (486) Show / Hide 
Range on Protein: 199-352
Range on HMM: 1-305/486
Sequence Identity: 14% (45 aa)

LRFSQVIQEGGHA---VVWAGRLQGEM---------------------------VAIKAFP---PRAVAQFRA--------------ERAVYQLLG---L
... ... ||      .|. |...|..                           ||.|      . . ..|..              | .. ...    .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

QHDHIVRFIT-AGQGGPGP-----LPSGPL-LVLELYPKGS----LCHYLTQY-----------------------------------------------
.|..|||..    ||.| |     . ..|. .|.|. |.|.    | .|| .                                                
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

----------TSDWGSSLR-------------------MALSLAEGLAFLHEERWQDGQYKPGIAHRDLSSQNVLIREDRS-----------CAIGDLGL
          . .    |.                   |.. .|.|...||. . . .   ... ||||   |.|. |.             | |.| ||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCE-F--IQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGL

A------L
.      |
SRQGSGVL
Kinase MISR2.AA TyrKc 199-501 18 2.1e-14 10.34 SMART 1-280 (280) Show / Hide 
Range on Protein: 199-501
Range on HMM: 1-280/280
Sequence Identity: 18% (62 aa)

LRFSQVIQEGGHAVVWAGRLQGEMVAIKAFPPRAVAQFRAERAVYQLLGL--QHDHIVRFITAGQGGP------GPLPSGPLLVLELYPKGSLCHYLTQY
... ... ||   .|. |..  ..||.|   . |.. |. |  .  .  |  .|..|||.. .   .       .||    ..|.|. |.|.| .||  .
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDAREDFMREARI--MCKLGGHHPNIVRLYGVCTQQGRNFMYIEPL----MIVMEYMPHGDLKDYLRKH

TS--DWGSSLRMALSLAEGLAFLHEERWQDGQYKPGIAHRDLSSQNVLIREDRSCAIGDLGLALVLPGL----AQPPALAPT---QPRGPAAILEAGTQR
     .   | ...  |.| ..||.          .. ||||   |.|. |.. . |.| ||.  .       .      ..   . ...  |      |
RPKLCMKDLLSFCWQIACGMEYLHSK---------NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPI------R

YMAPELLDKTLDLQDWGTALQRA------DVYSLALLLWEILSRCSDLRPD-HR--PPPFQLAYEAELGSNPSACEL----WALAVEERKRPNIPSTWSC
 |||| .             .        ||.|   ..|||....    |.      .....    . |  .   .                        
WMAPECI-------------NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS------------------

SATDPRGLRELLEDCWDADPEARLTAECVQQRL
. . |  . .. ..||..||| | | . . ...
FVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase MISR2.AA MLK 199-351 25 1.3e-13 43.69 In-house 1-180 (291) Show / Hide 
Range on Protein: 199-351
Range on HMM: 1-180/291
Sequence Identity: 25% (48 aa)

LRFSQVIQEGGHAVVWAGRLQGEM-----VAIKAFPPRA----VA---QFRAERAVYQLLGLQHDH----IVRFITAGQGGPGPLPSGPLLVLELYPKGS
..|...|..|.  .|| || ...      ||.|..  |.    ..   |   |. ...|  |.|      |..|     |.    |.. ..|.|  ..||
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFY----GVCLQPPCHFCIVMEYCEGGS

LCHYLTQYTS---------------DWGSSLRMALSLAEGLAFLHEERWQDGQYKP-GIAHRDLSSQNVLIRE------DRSCAIGDLGLA
|...|   .|               | .. .. ||  |.|...||..       .|  | |||| |.|.|| |      .. . | | |..
LYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSM-------APKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTS
Kinase MISR2.AA TKL-Unique 201-420 26 1.8e-12 40.43 In-house 1-225 (290) Show / Hide 
Range on Protein: 201-420
Range on HMM: 1-225/290
Sequence Identity: 26% (66 aa)

FSQVIQEGGHAVVWAGRLQGEMVAIKAFPP--RAVAQFRA--ERAVYQLLGLQ-HDHIVRFITAGQGGPG---PLPSGPLLVLELYPKGSLCHYLTQ---
|. .|.||| ..|  |   |. |||| | |      ...   |. |  .  |. |. ||...    |.     . |.   .|.| .| |||  .|.|   
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYM----GYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNN

--------YTSDWGSSLRMALSLAEGLAFLHEERWQDGQYKPGIAHRDLSSQNVLIRED-----RSCAIGDLGLALVLPGLAQPPALAPTQPRGPAAILE
        .. ..   ..||.  | |. .|| .       .| |.|||| |.|.|. ..      .  | | ||. ..    . ..  ..  |      .
NNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCE------PP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTR---NQTR

AGTQRYMAPELLDKT-LDLQDWGTALQRADVYSLALLLWEILSRC
 |. |.||||.|     . .      . .|||| .  ||||..|.
CGSFRWMAPEVLRMNFCQYS------EKSDVYSFGIVLWEIATRK
Kinase MISR2.AA Pkinase_Tyr 199-351 25 2.8e-11 38.81 Pfam 1-158 (270) Show / Hide 
Range on Protein: 199-351
Range on HMM: 1-158/270
Sequence Identity: 25% (43 aa)

LRFSQVIQEGGHAVVWAGRLQ------GEMVAIKAFPPRAVAQ------FRAERAVYQLLGLQHDHIVRFITAGQ--GGPGPLPSGPLLVLELYPKGSLC
..| ... ||   .|. |..       .  ||.|  .. |  .      | .| ..   || .|..|||.. .    |.|.     ...|.|. |.|.| 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLG-HHPNIVRLYGVCTDQGEPN----QIYIVMEYMPHGDLL

HYLTQY-----TSDWGSSLRMALSLAEGLAFLHEERWQDGQYKPGIAHRDLSSQNVLIREDRSCAIGDLGLA
.|| .        .    | |..  |.|...|.. .         . ||||   |.|. |.. . |.| |||
DYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---------CIHRDLAARNCLVTENNVVKICDFGLA
Kinase MISR2.AA UTK 199-351 20 4.7e-11 34.07 In-house 1-175 (296) Show / Hide 
Range on Protein: 199-351
Range on HMM: 1-175/296
Sequence Identity: 20% (40 aa)

LRFSQVIQEGGHAVVWAGRLQ------GE-MVAIKAFPPRAVAQFRAE---------R--AVYQLLGLQHDHIVRFI---TAGQGGPGPLPSGPLLVLEL
..... . .|   .|  .|..      .|  ||.|.  ..|.||.  |         |  .... .   | ...|..   |....        ...|.|.
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFH-WHPNVLRLVGVCTQEEP--------WMIVTEY

YPKGSLCHYLTQYTSDWG---------SSLRMALSLAEGLAFLHEERWQDGQYKPGIAHRDLSSQNVLIREDR-------SCAIGDLG---LA
...|.| .||   . . .         . | ||.  |.|...||.          |. ||||  .|.|. ..|       .|.|.|.|   ..
MENGDLRSYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSC---------GFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMS
Kinase MISR2.AA RGC 382-427 31 7.2e-07 20.4 In-house 171-224 (300) Show / Hide 
Range on Protein: 382-427
Range on HMM: 171-224/300
Sequence Identity: 31% (17 aa)

YMAPELLDKTLDLQDWG------TALQRADVYSLALLLWEILSRCS--DLRPDH
..|||.|  ..  ..||      .  |..||||..  . ||. |..  ||.|..
WTAPEHLREWRMPHQWGPHRQTQRGTQKGDVYSFGIIMYEIITRKGPWDLEPFC
Kinase MISR2.AA RGC 382-427 31 8e-07 20.4 In-house 171-224 (300) Show / Hide 
Range on Protein: 382-427
Range on HMM: 171-224/300
Sequence Identity: 31% (17 aa)

YMAPELLDKTLDLQDWG------TALQRADVYSLALLLWEILSRCS--DLRPDH
..|||.|  ..  ..||      .  |..||||..  . ||. |..  ||.|..
WTAPEHLREWRMPHQWGPHRQTQRGTQKGDVYSFGIIMYEIITRKGPWDLEPFC
Kinase MISR2.AA RGC 219-257 29 2e-06 18.98 In-house 1-44 (300) Show / Hide 
Range on Protein: 219-257
Range on HMM: 1-44/300
Sequence Identity: 29% (13 aa)

QGEMVAIKAFPPR----AVAQFRAERA-VYQLLGLQHDHIVRFI
.|..|.|| .. |    ..   |...  ..|.  ||||....||
EGDWVWIKKHNQRNLFRHWDFTRSMMRELKQMRQLQHDNLNKFI
Kinase MISR2.AA RGC 219-257 29 2e-06 18.98 In-house 1-44 (300) Show / Hide 
Range on Protein: 219-257
Range on HMM: 1-44/300
Sequence Identity: 29% (13 aa)

QGEMVAIKAFPPR----AVAQFRAERA-VYQLLGLQHDHIVRFI
.|..|.|| .. |    ..   |...  ..|.  ||||....||
EGDWVWIKKHNQRNLFRHWDFTRSMMRELKQMRQLQHDNLNKFI
Kinase MISR2.AA MLK 453-501 30 2.5e-05 14.61 In-house 249-291 (291) Show / Hide 
Range on Protein: 453-501
Range on HMM: 249-291/291
Sequence Identity: 30% (15 aa)

AVEERKRPNIPSTWSCSATDPRGLRELLEDCWDADPEARLTAECVQQRL
......|| ||||       |... .|...||..||. | .   ..| |
VAYNGLRPPIPST------CPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase MISR2.AA TK 471-501 32 3.3e-05 12.57 In-house 456-486 (486) Show / Hide 
Range on Protein: 471-501
Range on HMM: 456-486/486
Sequence Identity: 32% (10 aa)

TDPRGLRELLEDCWDADPEARLTAECVQQRL
..|  . .|. .||..||| | | . ....|
CPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase MISR2.AA MLK 377-419 34 8.5e-05 12.72 In-house 194-232 (291) Show / Hide 
Range on Protein: 377-419
Range on HMM: 194-232/291
Sequence Identity: 34% (15 aa)

AGTQRYMAPELLDKTLDLQDWGTALQRADVYSLALLLWEILSR
||| ..|||| . .       ..    .||.| ...|||.|.|
AGTYAWMAPEVIQQ----FRCEKYSEKCDVWSWGVVLWEMLTR
Kinase MISR2.AA TKL-Unique 454-491 36 0.000272 11.25 In-house 249-280 (290) Show / Hide 
Range on Protein: 454-491
Range on HMM: 249-280/290
Sequence Identity: 36% (14 aa)

VEERKRPNIPSTWSCSATDPRGLRELLEDCWDADPEAR
.||..|| ||. .      |  .|.|...||. ||. |
MEENYRPPIPNHC------PKEYRDLIQQCWHHDPSQR
Kinase MISR2.AA UTK 473-501 31 0.000317 10.36 In-house 268-296 (296) Show / Hide 
Range on Protein: 473-501
Range on HMM: 268-296/296
Sequence Identity: 31% (9 aa)

PRGLRELLEDCWDADPEARLTAECVQQRL
|. . .|. .|| .||. | ..| . |..
PHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase MISR2.AA Pkinase_Tyr 473-501 34 0.000893 13.41 Pfam 242-270 (270) Show / Hide 
Range on Protein: 473-501
Range on HMM: 242-270/270
Sequence Identity: 34% (10 aa)

PRGLRELLEDCWDADPEARLTAECVQQRL
|  . .|. .||..||| | | . ....|
PDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase MISR2.AA RGC 476-503 34 0.00272 7.69 In-house 272-300 (300) Show / Hide 
Range on Protein: 476-503
Range on HMM: 272-300/300
Sequence Identity: 34% (10 aa)

LRELLEDCWDADPEARLT-AECVQQRLAA
| .|..|||. ||| | . .. ..  |. 
LLHLMRDCWAEDPEERPDMFDQIRKQLKT
Kinase MISR2.AA RGC 476-503 34 0.002895 7.69 In-house 272-300 (300) Show / Hide 
Range on Protein: 476-503
Range on HMM: 272-300/300
Sequence Identity: 34% (10 aa)

LRELLEDCWDADPEARLT-AECVQQRLAA
| .|..|||. ||| | . .. ..  |. 
LLHLMRDCWAEDPEERPDMFDQIRKQLKT
Kinase MISR2.AA TK 405-420 43 0.0804 1.02 In-house 376-391 (486) Show / Hide 
Range on Protein: 405-420
Range on HMM: 376-391/486
Sequence Identity: 43% (7 aa)

DVYSLALLLWEILSRC
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DVWSFGVLMWEIFTYG
Kinase MISR2.AA UTK 405-419 40 0.092816 1.8 In-house 222-236 (296) Show / Hide 
Range on Protein: 405-419
Range on HMM: 222-236/296
Sequence Identity: 40% (6 aa)

DVYSLALLLWEILSR
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DVWSFGVVCWEIWTW
Kinase MISR2.AA Pkinase_Tyr 405-420 43 3.931397 1.07 Pfam 196-211 (270) Show / Hide 
Range on Protein: 405-420
Range on HMM: 196-211/270
Sequence Identity: 43% (7 aa)

DVYSLALLLWEILSRC
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DVWSFGVLMWEIFTYG