Gene MPSK1 (Mouse)

MPSK1

Species: Mouse
Alias: Stk16, MPSK1
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: Other
Family: NAK
Subfamily: MPSK

Sequence

Name Sequence Type Origin Length Description Download
MPSK1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 271 Kinase domain by global Sugen HMM Fasta, JSON
MPSK1.AA Protein Sugen 305 None Fasta, JSON
MPSK1.NA RNA Sugen 1469 None Fasta, JSON

Protein domain

Protein domains of MPSK1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase MPSK1.AA MPSK 20-290 65 4.90000000001e-227 760.52 In-house 1-281 (281) Show / Hide 
Range on Protein: 20-290
Range on HMM: 1-281/281
Sequence Identity: 65% (185 aa)

YLFVQKLGEGGFSYVDLVEGLHDGHFYALKRILCHEQQDQEEAQREAEMHRLFQHPNILRLMAY-SLKERG-----AKHEAWLLLPFFKKGTLWNEIERL
|.|.|.|||||||||||||.||||||||||||.|||||||..||||||||..|.||||.||... .||.|.     .|||.||.||.||.||||....|.
YYFMQRLGEGGFSYVDLVENLHDGHFYALKRIQCHEQQDQNQAQREAEMHCQFDHPNIIRLVDWGCLKGREDIVINTKHEIWLVLPYFKHGTLWDHLQRM

KDQGSFLTEDQILPLLLGISRGLEAIH---AKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIQVEGSRQALALQDWAAQRCTISYRAPELFSVQSHC
||.|...|||||....||...||.|||   .|.|||||.|||||.|||..|||.|||||||.|||||.|.|||.|||||||.||...|||||||.|||||
KDKGDCMTEDQIWWIFLGVCEGLKAIHEAMPKPYAHRDMKPTNICLGDDFQPVIMDLGSMNEACIQVKGQRQACALQDWAAERCSMVYRAPELFHVQSHC

VIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVALAVQN-ELSIPQSPRHSSALRQLLSSMMTVDPQQRPHIPVLLSQL
|||||||.||||||||||.....||||..|.||||.||||| ...||...|.|....||.|.||.|||..||||...|.|.
VIDERTDIWSLGCVLYAMCYFHSPYDMIYQRGDSVHLAVQNRNFNIPENSRYSQDMHQLISYMMRVDPMERPHIFWVLNQT
Kinase MPSK1.AA NAK 20-290 38 2.7e-148 498.22 In-house 1-299 (299) Show / Hide 
Range on Protein: 20-290
Range on HMM: 1-299/299
Sequence Identity: 38% (114 aa)

YLFVQKLGEGGFSYVDLVE---------GLHDGHFYALKRILCH-EQQDQEEAQREAEMHRLFQHPNILRLMAY-SLKERG---AKHEAWLLLPFFKKGT
| ....|.|||||||.||.         ....|..|||||..|| ..||.....||.||....||.|..... . ...||     ..|..||......|.
YTVEKYLAEGGFSYVYLVQDNYINHPDNPNSNGEKYALKRMICHSDEQDLNACKREIEMMKKLQHHNNIVQYIDSHINERDDSNGTWEVFLLMEYCCHGS

LWNEIERLK-DQGSFLTEDQILPLLLGISRGLEAIH----AKGYAHRDLKPTNILLGD---EGQPVLMDLGSMNQACIQVEGSRQALA---LQDWAAQRC
||..... . |.|...|||.|| ..... .|..|.|    .|...|||.|..||||..   .|...|.|.|||..|.||.|....|..   .|||.....
LWDLMNKRLMDKGTCFTEDEILQIFCDVCEGVQAMHQCQPPKPIIHRDIKIENILLSESHHDGNYKLCDFGSMTTAIIQPENRWEAQYRSMVQDWINKYT

TISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVALAVQN---ELSIPQSPRHSSALRQLLSSMMTVDPQQRPHIPVLLSQL
|..|||||.. ..|.|.|||..|.|.|||.||.|.|.. |.....|..||..||.||   ..|||...|.|.....| . |.|.||.|||.|. .|.||
TPMYRAPEMCDLYSNCPIDEKVDIWALGCMLYKMCFYTHPFEDCYQRHDSSKLAIQNGNYKYSIPDNSRYSQQMHDLIRYMLTPDPEQRPNIYQVLNQL
Kinase MPSK1.AA NAK-Unclassified 20-292 20 1.1e-64 221.22 In-house 1-405 (405) Show / Hide 
Range on Protein: 20-292
Range on HMM: 1-405/405
Sequence Identity: 20% (84 aa)

YLFVQKLGEGGFSYVDLV---------E-----GLHDGHFYALKRILCHEQQDQEEAQREAEMHRLFQ-HPNILRLMAYSLK--ERG-AKHEAWLLLPFF
|  |  |.|||||.| ||               ..  .  |.|||..| ...  ... || .  ..|. ||||  .  ..     ..    |  .|... 
YTIVRYLAEGGFSFVYLVKFSKYINPPDNTASVPHSNSNMYCLKRMICQDEESLNTMKREIDVMKRFRNHPNIVKYIDHHIMRENHNNQSYEVFMLMEYC

KKGTLWNEIE-----RLKD-QGSFLTEDQILPLLLGISRGLEAIHAKGY----------------------------------------------AHRDL
. |.|   .        ..  .....|  .|   ... .|. . |.                                                 .|||.
SRGSLQDFMNNQRTIYQRLTEQTRFHEQECLQIMSDVCQGIQCMHQHQPRQDNATSRVNVDAVSMTYSDETAMLLEDTPLEMDMLSSNSAGSIPLIHRDI

KPTNILLG----------------------------------------------------------DEGQPVLMDLGSMNQACIQVEGSRQALALQDWAA
|. |.|.                                                           ..| ..|.|.||  .. | .| . ... ||||  
KIENVLFCNLRRPSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSEDSEHNGIYKLCDFGSCCECIITIENRQEMQYLQDWIN

QRCTISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKG-DSVALAVQN---ELSIPQSPRHSSALRQLLSSMMTVDPQQRPHIPVLL
. .|  |||||..   . |.|||. |.|.||| || |.|.  | .|  | .  ||.... .     ..|  ...|. | .|   |  .|| |||.|  .|
MHTTPQYRAPEMIDLYRCCPIDEKIDIWALGCFLYKMCFYTTPFEMCGQLHNASVTYKILHGLGKYEFPSNHNYSNQLHNLIKIMLNEDPIQRPNIYQVL

SQLEA
 ..  
NHICQ
Kinase MPSK1.AA S_TKc 20-297 22 3.1e-44 154.18 SMART 1-231 (231) Show / Hide 
Range on Protein: 20-297
Range on HMM: 1-231/231
Sequence Identity: 22% (63 aa)

YLFVQKLGEGGFSYVDLVEGLHDGHFYALKRILCHEQQDQEEAQREAEMHRLFQHPNILRLMAYSLKERGAKHEAWLLLPFFKK--GTLWNEIERLKDQG
| ...|.|.|.|. | ..   ..|. .|.|.|        | ..|| ....  .|||| .|  .        .. .. . .     |.|   |.. . .|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKKRGRHG

SF--LTEDQILPLLLGISRGLEAIHAKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIQVEGSRQALALQDWAAQRCTISYRAPELFSVQSHCVIDE-
    ..| ..  ..  | ..|| .| .|  |||||| |||| .  .  . | |.  |                   .  |  |.|||..        .  
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------------TTFCGTPWYMAPEVL------GYGKC

RTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVALAVQNELSIPQSPRHSSALRQLLSSMMTVDPQQRPHIPVLLS--QLEALQPPA
. |.||.||.|| |. |. |..        ...  .. .        |. ...... ....||..|| .  .|   .. .. |  
KCDWWSCGCILYEMLCGYPPFP-------QMQMMFKKIG--------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase MPSK1.AA Pkinase 20-290 21 7.3e-40 142.04 Pfam 1-293 (293) Show / Hide 
Range on Protein: 20-290
Range on HMM: 1-293/293
Sequence Identity: 21% (67 aa)

YLFVQKLGEGGFSYVDLVEGLHDGHFYALKRILCHEQQDQEE--AQR--EAEMHRLFQHPNILRLMAYSLKERGAKHEAWLLLPFFKKG----TLWNEIE
| ...|.|.|.|. | .     .|. .|.|.|  ... ....  . |  |..... ..||||.||  .       | . .. ...  .|     |.   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED----KDHIYMVMEYCEGGLYVMDLF---D

RLK--DQGSF-LTEDQILPLLLGISRGLEAIHAKGYAHRDLKPTNILLGDEGQP----VLMDLGSMNQACIQVEGSRQALALQDWAAQRCTISYRAPELF
...  ..|.| ..|...   .. | |||| .|..|  |||||| |||. ..|..     . | |.  |.             .      .|. |.|||. 
YISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--------Y-NNS-MTTFCGTPWYMAPEV-

SVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGD----------SVALAVQNELSIPQSPRHS-------------------SALRQLLSSMMTV
 ....  .. . |.||.||.|| |..|.      |. |.           ...  . .|. . .  .|                   .......... ..
-IRGGQYYGPKVDMWSCGCILYEMLCGR----PPFP-GHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCK

DPQQRPHIPVLLSQ--L
||..|| .. .|    .
DPKKRPTAEQILQHPWF
Kinase MPSK1.AA TKL 26-290 15 4.6e-31 109.11 In-house 1-364 (364) Show / Hide 
Range on Protein: 26-290
Range on HMM: 1-364/364
Sequence Identity: 15% (59 aa)

LGEGGFSYVDLVEGLHDG----------HFYALKRILCHE---------------------------QQDQEEAQREAEMHRLFQHPNILRLMAYSLKER
.|.|||.      | . |             | |..  |.                           .. ...  .|. |.. ..||||...|.|.. ..
IGSGGFG--EVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPP

G--AKHE-------AWLLLPFFKKGTLWNEIERLKDQGSFLTEDQILPLLLGISRGLEAIHA--------KGYAHRDLKPTNILLGDEGQ----------
.  . ..        ..   . ..|.|.. .            .|.. . |.|.||..  |.        .. .|||||. |||. . ..          
CGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPN

----PVLMDLGSMNQACIQVEGSRQALALQDWAA------------QRCTISYRAPELFS---VQSHCV----------IDERTDVWSLGCVLYAMMFGE
    . . |.|     .   . .... . .                |. |. . |||..      ...|           .|..||.| | ||. .. ..
ADWCCKICDFGLSRFMSQSGNMNDTMTTMME--SAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRC

GPY---DMVFQKGD-------SVALAVQNELSIPQSPRH-------SSA---LRQLLSSMMTVDPQQRPHIPVLLSQL
 ||   ..  ...        ...   .. . ||  ...       ...   ...|.   .  ||..||    .|..|
RPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase MPSK1.AA Ciliate-E2 20-281 17 6.7e-31 103.29 In-house 1-353 (365) Show / Hide 
Range on Protein: 20-281
Range on HMM: 1-353/365
Sequence Identity: 17% (66 aa)

YLFVQKLGEGGFS-----YVDLVEGL------------------HDGHFYALKRILCHEQQDQEEAQREA-EMH----RLFQ---------HPNILRLMA
| |..|.|.|.|.      |..|  .                   .. .||.|..   . . ..  ...  |..    .. .         ||||...  
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKI-NEKNILEQLNHPNIIKM--

YSLKERGAKHEAWLLLPFFKKGTLWNEIERLKDQGSFL-------TEDQILPLLLGISR---------------GLEAIHAKG-YAHRDLKPTNILLGDE
|   .   ..   | . ... |.|.  |.  | .  .        || .|. .   | .               .|| .| |.   |||.|| |||.   
YECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF---

GQPVLMDLGS------MNQACIQVEGSRQALALQDW-------------------AAQRCTISYRAPELFSVQS------HCVIDERTDVWSLGCVLYAM
  . . |.|        || ...  .... . ..                       . .|  | ||| .. ..      .   |.  |.||||..|| |
--IKIIDFGLSKKYDDDNQNRTH--KQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEM

MFGEGPYDMVFQKGDSVALAVQN-ELSIP----------------QSPRHSSALRQLLSS----MMTVDPQQRP
.||. |.              .. ....|                    .|    .|..     |. .||..|.
LFGKPPF----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRI
Kinase MPSK1.AA BIKE 24-283 29 6.3e-24 82.58 In-house 5-261 (267) Show / Hide 
Range on Protein: 24-283
Range on HMM: 5-261/267
Sequence Identity: 29% (78 aa)

QKLGEGGFSYVDLVEGLHDGHFYALKRILCHEQQDQEEAQREAE-MHRLFQHPNILRLMAYSLKERGAK-HEAWLLLPFFKKGTLWNEIERLKDQGSFLT
..| ||||. | || . |.|  .||||     ..| . . || . |. .  | ||   .  .    |    |  .| .. ..  . | . .   || ..|
EQLAEGGFAMVFLVRD-HKGNKCALKRMYVNNEHDLNVCCREHQIMKQCSGHKNIVGYVDCYINCIGNGVWECMILMEYCRH-QVVNMMNQRLQQGQYFT

EDQILPLLLGISRGLEAIHAKGY--AHRDLKPTNILLGDEG--QPVLMDLGSMNQACIQVEGSRQALALQDWAAQRCTISYRAPELFSVQSHCVIDERTD
|. .|     .      .|       |||||  |||| |.|    || | ||      ...      . .|   .  |..|||||.    |   |  . |
EQEVLQIFCDVCEAVSRLHHCQTPIIHRDLKVENILLHDHGPPHYVLCDFGSATNKFLNPQ-KHGVNYVKDEIEKYTTMCYRAPEMIDLYSGKEITTKAD

VWSLGCVLYAMMFGEGPYDMVFQKGDSVALAVQN-ELSIPQSPRHSSALRQLLSSMMTVDPQQRPHI
.| ||| || . |   |.      | |  ||... . .|| ... |  ...|   |. .|. .|| |
IWALGCMLYKLCFFCLPF------GES-QLAICDGNFTIPDNSKYSREMHCLIRYMLEPDMEKRPDI
Kinase MPSK1.AA Ciliate-E2-Unclassified 20-281 19 7.6e-23 76.09 In-house 1-341 (352) Show / Hide 
Range on Protein: 20-281
Range on HMM: 1-341/352
Sequence Identity: 19% (70 aa)

YLFVQKLGEGGFSYVDLVEGLHDGHFY-----ALKRILCH-EQQDQEEAQREAEMHRLFQ---------------------HPNILRLMAYS--------
| .....|.|||. | ...   .. .|     . | . ..  |. ... .   ||.....                     ||.|.... .         
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

-------------LKERGA---KHEAWLLLPFFKKGTLWNEIERLKDQGSFLTEDQIL-----PLLLGISRGLEAIHAKG-YAHRDLKPTNILLGDEG--
             .|.|.    |                |.. . . |.  .|| |..      ..  |  ||| .| |.   |||.|| |||. ..|  
VMEYCEGGDLWQYIKKRKKQKQK---------------GNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKN

-QPVLMDLGS--MNQACIQVEGS----RQALALQDWAAQRC-TISYR----APELFSVQSHCVIDER----TDVWSLGCVLYAMMFGEGPYDMVFQKG--
 .. . |.|.   .| ... .      ...   |. . ..| |..|     |||..  | .   |..     |.||||..||.|.||. |..   ..   
YYIKIIDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNY---DHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQ

-------------DSVALAVQNELSIPQSP-----RHSSALR-----QLLSSMMTVDPQQRP
                    |.....| .|      |.|        .||..|. ..| .|.
QLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRI
Kinase MPSK1.AA STE 20-163 19 1.6e-16 54.95 In-house 1-186 (359) Show / Hide 
Range on Protein: 20-163
Range on HMM: 1-186/359
Sequence Identity: 19% (38 aa)

YLFVQKLGEGGFS--YVDLVEG---LH----------DGHFYALKRILCHEQ-----------------QDQEEAQREAEMHRLFQ--HPNILRLMAYSL
. ...|.|.|.|   |  .      .|           | ..| |..   ..                 ..... ..| .... ..  |||| .   . .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

KE---RGAKHEAWLLLPFFKKGTLWNEIE-RLKDQG---------SFLTEDQILPLLLGISRG-LEAIHAKGYAHRDLKPTNILLGDEGQPV
||    ....| |. . .   |.|   |. . . ..         ... |.||   .  | .| |. .| ... |||.|| ||||      |
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL------V
Kinase MPSK1.AA CAMK 25-156 16 1.2e-15 46.26 In-house 1-212 (425) Show / Hide 
Range on Protein: 25-156
Range on HMM: 1-212/425
Sequence Identity: 16% (36 aa)

KLGEGGFSYVDLVEGLHDG------------HFYALKRILCH----------------------------EQQDQEEAQREAEMHRLFQ-------HPNI
.||.|.|. | |..  ...            . .| | |                               ...|... .|| |.... |       ||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LRLMAYSLKER---------GAKH-------EAWLLL---PFFKKGTLWNE-IERLKDQGSF--------------LTEDQILPLLLGISRGLEAIHAKG
..|  .   ..           ..       . .. .    .   | |  .  ......|..              .||..   .   |  ... .| ..
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

YAHRDLKPTNILL
 .|||||| ||||
IVHRDLKPENILL
Kinase MPSK1.AA TyrKc 20-290 19 9.4e-12 -32.64 SMART 1-280 (280) Show / Hide 
Range on Protein: 20-290
Range on HMM: 1-280/280
Sequence Identity: 19% (59 aa)

YLFVQKLGEGGFSYVDLVEGLHDGHFYALKRILCHEQQDQEEAQREAEMHRLF--QHPNILRLMAYSLKE--RGAK---HEAWLLLPFFKKGTLWNEIER
  . .||||| |  | . .        | | .  .    .|.  |||.. . .  .||||.|| .. ...  .      .  .... . ..| | . . .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN--FMYIEPLMIVMEYMPHGDLKDYLRK

LKDQGSFLTEDQILPLLLGISRGLEAIHAKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACI------QVEGSR-------QALALQDWAAQR--CTIS
 ...   |. .. |   . |..| | .| |.. ||||   |.|.|...           .. |         ..        .    .     .    | 
HRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIR

YRAPELFSVQSHCVIDERTDVWSLGCVLY-AMMFGEGPYD-MVF--QKGDSVALAVQNELSIPQSPR--------HSSALRQLLSSMMTVDPQQRPHIPV
  ||| .    ...  . .|||| | ...  . .|. ||  |..   . . |   |..    || |          .... |. ..    || .||    
WMAPECI---NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSE

LLSQL
. ...
IHECF
Kinase MPSK1.AA NEK 20-77 28 6.6e-09 27.91 In-house 1-66 (286) Show / Hide 
Range on Protein: 20-77
Range on HMM: 1-66/286
Sequence Identity: 28% (19 aa)

YLFVQKLGEGGFSYVDLVEGLHDGHF-----YALKRILCHE--QQDQEEAQ-REAEMHRLFQHPNI
|  ..|.|.| |. | .|.   ||       |..|.|   .  ......||  |.   .  .||||
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNI
Kinase MPSK1.AA CAMK 195-283 18 8.7e-09 23.69 In-house 282-416 (425) Show / Hide 
Range on Protein: 195-283
Range on HMM: 282-416/425
Sequence Identity: 18% (25 aa)

TISYRA-PELFSVQS-----------HCVIDERTDVWSLGCVLYAMMFGEGPYD---------------------MVFQKGD-SVALAVQNELS------
| .| | ||... ..           .  ... .|.||.|..||.|  |. |..                        .||. .       ..|      
TPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPE

--------IPQSPRHSSALRQLLSSMMTVDPQQRPHI
        . ..   |   ..|...|..|||..|. |
WWDDISDEF-HH-FVSQECKDLIRKMLQVDPEKRMTI
Kinase MPSK1.AA NEK 103-160 27 2e-06 18.99 In-house 91-156 (286) Show / Hide 
Range on Protein: 103-160
Range on HMM: 91-156/286
Sequence Identity: 27% (18 aa)

KGTLWNE---IERLKDQGSFLTEDQILPLLLGISRGLEAIHAK-----GYAHRDLKPTNILLGDEG
.|.| .    |.. |..| .. |.||.  .  .. .|  .| .        |||.|| || | ...
GGDLYQKIKSIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNN
Kinase MPSK1.AA STE 200-293 16 2e-06 18.75 In-house 230-359 (359) Show / Hide 
Range on Protein: 200-293
Range on HMM: 230-359/359
Sequence Identity: 16% (22 aa)

APELFSVQSHC---VIDERTDVWSLGCVLYAMMFGEGPY---DMV---FQKGDSVALAV---------QNELSIPQ-----------------SPRHSSA
|||  . ....     |.. |.|||||..  |  |. |.         |.. .. . .          ..  ..|.                 . . |. 
APEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPE

LRQLLSSMMTVDPQQRPHIPVLLSQ-LEAL
... ..   . ||..||    ||.   . .
FKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase MPSK1.AA NEK 213-226 64 2.6e-05 15.1 In-house 202-215 (286) Show / Hide 
Range on Protein: 213-226
Range on HMM: 202-215/286
Sequence Identity: 64% (9 aa)

DERTDVWSLGCVLY
... |.||||||||
NNKSDIWSLGCVLY
Kinase MPSK1.AA NEK 262-292 35 3.4e-05 14.68 In-house 256-286 (286) Show / Hide 
Range on Protein: 262-292
Range on HMM: 256-286/286
Sequence Identity: 35% (11 aa)

SSALRQLLSSMMTVDPQQRPHIPVLLSQLEA
|. |..|.|.| ..||.||| .  .|..   
SQDLQNLISQMLQKDPEQRPSCNQILEMPFI