Gene SgK396 (Mouse)

SgK396

Species: Mouse
Alias: Stk31, SgK396
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: Other
Family: Other-Unique

Sequence

Name Sequence Type Origin Length Description Download
SgK396.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 239 Kinase domain by global Sugen HMM Fasta, JSON
SgK396.NA RNA Sugen 3238 None Fasta, JSON
SgK396.AA Protein Sugen 1018 None Fasta, JSON

Protein domain

Protein domains of SgK396.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
TUDOR SgK396.AA TUDOR 28-147 28 2.4e-33 121.91 Pfam 1-128 (128) Show / Hide 
Range on Protein: 28-147
Range on HMM: 1-128/128
Sequence Identity: 28% (37 aa)

THYNKVEDVVGSHVEDAVTFWA--QNVSKNKDIMKIGCSLSEVCPLANS--VFGNLDPKKIYGGLFSEDKCWYRCKV--LKTISDDKCLVRYIDYGNTEI
 ....  .|. .|.|.. .||.  |...  ... |. ....|..  .    .. .. |....  .||.|.||||...  .. ..|... |.||||||||.
IPEGEYMCVYVTHIESPCHFWIHQQPHEDDHKLEKMMEEMQEYYNCKPPDYECYPPKPGDGCCCVFSCDGCWYRAMIVVTCCVDDQCVEVFYIDYGNTEY

LNRSDIVEIP-PELQF-SSIAKKYRLWG
...||| .|| ||...    |.|..|.|
VPFSDIRQIPPPEFMHLPFQAFKCCLAG
TUDOR SgK396.AA TUDOR 81-135 38 5.4e-11 43.77 SMART 1-60 (60) Show / Hide 
Range on Protein: 81-135
Range on HMM: 1-60/60
Sequence Identity: 38% (23 aa)

PKKIYG----GLFSEDKCWYRCKVLKTISD-DKCLVRYIDYGNTEILNRSDIVEIPPELQ
||   |      .||| |||||.. |  .| ... |..|||||.| ....|| ..|... 
PKWKVGQMCCARWSEDGCWYRCRIIKVDPDNQWYEVFFIDYGNCEWVPWWDIRQMPCKHM
Kinase SgK396.AA Other-Unique 740-974 13 9.1e-34 112.01 In-house 1-249 (249) Show / Hide 
Range on Protein: 740-974
Range on HMM: 1-249/249
Sequence Identity: 13% (36 aa)

LSSKRPLVCSEVNGQPVLLKGYSVDVDTEGRVIQRAASYHRACGYAKEESGLLP-------------LIFLFLCKSDPVAYLMVPYYPKANLSAVQASMP
. .    ....|..|   .|.......|  ..| ....... . . ...... .             |.|......... |.|.|.|.. ..  .|... 
IKDIGKGTYGRVYKQHHNKKKKYCAKKTKHHKI-HCMDMDNNKRE-QIYHYQ-IIHCIFYWTMNHCHLCFCYEHCPNMIFYIMYPWYHHHCECQCQCEHW

LTSEEALKVMKGVARGLHTLHSANIIHGSLHQNNVFALNRE----------QGIVGDYDFTKSESQRASVNAMVGGLSLLSPELKTGKPPSASSDLYAYG
.  .. ....... .. |...  | ..  ..|||.... ..          .  ....|| .. . . ... .. ...  |||  .. |   ..|.|..|
MNCCHMIHNLHHLHNNNHIHCDINPNNIWINQNNIHMCHNCGHNIPTIIIEHQHIKIMDFNNN-N-MMYFAPEF-SCRWCSPETFDYWPLGEKIDQYHFG

CLFLWLSVQNQEFETNEDGIPKVDQFHLDDNVKSLLCSLIYFRSSMTAEQVLNAECFL
|.......|...|....  . . ......|.  .|.| .. ....| ...  | .||.
CYHFHMNCQHWIFHYHDV-QHWPPHESPKDI-HILICQCECCHQCM-VNPYQNPNCFY
S_TKc SgK396.AA S_TKc 734-973 12 3e-06 -84.28 SMART 1-231 (231) Show / Hide 
Range on Protein: 734-973
Range on HMM: 1-231/231
Sequence Identity: 12% (35 aa)

TEPMKEL---SSKRPLVCSEVN-GQPVLLKGYSVDVDTEGRVIQRAASYHRACGYAKEESGLLPLIFLFLCKSDPVAYLMVPYYPK--ANLSAVQASMP-
 | ....   .  .   | ... |. | .|  .       . |.|  . ..          .  |.  |        |.   | .    .|  .  ... 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-----HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGR

------LTSEEALKVMKGVARGLHTLHSANIIHGSLHQNNVFALNREQGIVGDYDFTKSESQRASVNAMVGGLSLLSPELKTGKPPSA-SSDLYAYGCLF
      ..  .| ..|. ....|  .|| .|||  |   |..  .  .  ..|  . .        . ..| .  ..||.    . .  ..| .. ||..
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

--------LWLSVQNQEFETNEDGIPKVDQFHLDDNVKSLLCSLIYFRSS--MTAEQVLN-------AECF
        ..   ... |.              .. .|.... .  .  .  .|| ..|.        . |
YEMLCGYPPFP-QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase SgK396.AA SgK496 820-919 34 4e-06 16.3 In-house 94-188 (265) Show / Hide 
Range on Protein: 820-919
Range on HMM: 94-188/265
Sequence Identity: 34% (34 aa)

AVQASMPLTSEEALKVMKGVARGLHTLHSANIIHGSLHQNNVFALNREQGIVGDYDFTKSESQRASVNAMVGGLSLLSPELKTGKPPSASSDLYAYGCLF
|..| | |  || |..   |. |.  |||  ..|  .   ||    .. . . |  | | |   .   ..||    . ||| |||    | | ||.| ||
AIKANMEL--EERLHIALDVVEGIRYLHSQGLVHRDIKLKNVLLDKHNRAKITDLGFCKPEAMMSG--SIVGTPIHMAPELFTGK-YDNSVDVYAFGILF
Kinase SgK396.AA Worm5 833-861 41 7e-06 13.84 In-house 109-137 (260) Show / Hide 
Range on Protein: 833-861
Range on HMM: 109-137/260
Sequence Identity: 41% (12 aa)

LKVMKGVARGLHTLHSANIIHGSLHQNNV
||.|  ....| ||||   ||  .| .|.
LKIMCCMSHSLQTLHSIGFIHRDCHWQNI
Kinase SgK396.AA SAK 826-932 28 2.9e-05 13.57 In-house 96-203 (254) Show / Hide 
Range on Protein: 826-932
Range on HMM: 96-203/254
Sequence Identity: 28% (31 aa)

PLTSEEALKVMKGVARGLHTLHSANIIHGSLHQNNVFALNREQGI-VGDYDF-TKSESQRASVNAMVGGLSLLSPELKTGKPPSASSDLYAYGCLFLWLS
| | ||| ..|. .  |.  ||| .|.|  |   |.  | |.  . . |.   |. .        | |    .|||. |  .    ||... ||..  | 
PFTEEEARHFMHQIVIGMLYLHSHGIMHRDLTLSNIL-LTRDMHCKIADFGLATQLKMPHEKHYTMCGTPNYISPEIATRTAHGLQSDVWSLGCMLYTLL

VQNQEFETN
.    |.|.
IGRPPFDTD
Kinase SgK396.AA RAF 835-919 21 9.6e-05 10.97 In-house 108-211 (282) Show / Hide 
Range on Protein: 835-919
Range on HMM: 108-211/282
Sequence Identity: 21% (22 aa)

VMKGVARGLHTLHSANIIHGSLHQNNVFALNREQGIVGDYDFTKSESQRA-----SVNAMVGGLSLLSPELKT--------------GKPPSASSDLYAY
. . |. |.  ||. ||||  |  ||.|  .  .  .||.   . ...        ..   .    ..||                   | |  || |..
ISRQVCQGMDYLHAKNIIHRDLKSNNIFLHEDMTVKIGDFGLMTVKTRWSPRGNQQFEQPTHWILWMAPEVIRNLMIDWRGDVLMQDENPYSFQSDVYSF

GCLF
|  .
GIVM
Kinase SgK396.AA LRRK 833-853 47 0.000157 11.93 In-house 167-189 (351) Show / Hide 
Range on Protein: 833-853
Range on HMM: 167-189/351
Sequence Identity: 47% (11 aa)

LKVMKGVARGLHTLHSAN--IIH
||..  .|.|.  |||.|  |||
LKIALQIAKGMEYLHSHNPPIIH
Kinase SgK396.AA Jak 833-854 31 0.000278 11.22 In-house 121-142 (299) Show / Hide 
Range on Protein: 833-854
Range on HMM: 121-142/299
Sequence Identity: 31% (7 aa)

LKVMKGVARGLHTLHSANIIHG
....|....|.|.|.. ..|||
MQFAKQICWGMHYLEDKRYIHG
Kinase SgK396.AA Ciliate-B3 832-895 22 0.000358 11.89 In-house 2-69 (69) Show / Hide 
Range on Protein: 832-895
Range on HMM: 2-69/69
Sequence Identity: 22% (15 aa)

ALKVMKGVARGLHTLHSANIIHGSLHQNNVFALNREQ----GIVGDYDFTKSESQRASVNAMVGGLSL
||| .. |   .  ||. || |  .  .|.   . ..     |. |.   ... |    ... | |. 
ALKHFHQVVEKIKILHEKNICHCDIKVDNILVNQQDKENYKVIIIDFGHCQRKCQNCKSEMICGTLTY
Kinase SgK396.AA PLK1 826-932 27 0.000429 9.06 In-house 95-202 (253) Show / Hide 
Range on Protein: 826-932
Range on HMM: 95-202/253
Sequence Identity: 27% (30 aa)

PLTSEEALKVMKGVARGLHTLHSANIIHGSLHQNNVFALNREQGIVGDYDF-TKSESQRASVNAMVGGLSLLSPELKTGKPPSASSDLYAYGCLFLWLSV
..|  |.   |. ...| . ||  .|||  |   |.|  .. |  .||.   || | .      . |    . ||. . |  |   |... ||..  | .
AITEPECRYYMYQIVEGCQYLHNNKIIHRDLKLGNLFLNDHLQVKIGDFGLATKCEYDGERKKTLCGTPNYIAPEVLNKKGHSFEVDIWSIGCIMYILLF

QNQEFETN
 .  |||.
GQPPFETK
Kinase SgK396.AA C8 842-919 22 0.000699 9.49 In-house 135-226 (226) Show / Hide 
Range on Protein: 842-919
Range on HMM: 135-226/226
Sequence Identity: 22% (21 aa)

GLHTLHSANIIHGSLHQNNVF-ALNREQG---IVGDYDF----TKSESQRASVN-AMVGGLSLLSPELKTG-----KPPSASSDLYAYGCLF
|. ..|. ||.|  .  .|    |. ..|      | .|    .|..|.  | .   .| .  . ||  ..     |  .  |||.  | . 
GVNYIHCKNIMHRDIKPHNFLVCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNTCGTWAYFAPEIEKKQDNQYKQYRIQSDLFSVGLVL
Kinase SgK396.AA Pkinase 826-853 33 0.000865 14.48 Pfam 102-131 (293) Show / Hide 
Range on Protein: 826-853
Range on HMM: 102-131/293
Sequence Identity: 33% (10 aa)

PL--TSEEALKVMKGVARGLHTLHSANIIH
..  . .|. ..|. ..|||  .|| .|||
CFYFSEWECKFYMYQILRGLEYCHSMGIIH