Gene STLK3 (Mouse)
STLK3
Sequence
Protein domains of STLK3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | STLK3.AA | FRAY | 75-349 | 77 | 5.2e-251 | 788.54 | In-house | 1-277 (277) | Show / Hide |
Range on Protein: 75-349 Range on HMM: 1-277/277 Sequence Identity: 77% (214 aa) YELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQ-TSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGE-HK ||||||||.||||||..|.|.||||..||||||||||| ||||||.||||||.||.|||||.|.|||||..||||||..|..||.|||.|.....|| || YELQEVIGEGATAVVHKAYCIPRQENCAIKRINLEKCQNTSMDELIKEIQAMCQCHHPNVVHYHTSFVVNEELWLVMRYLECGSCLDIMKFKMPQGEPHK NGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFG .||..|..|||||||||.||.|.|.|||||||.||||||.||||..|||||||||.||||||..|..||.|||||||||||||||||.|||||||.|||| QGVFDEHVIATILKEVLKGLCYFHKNGQIHRDIKAGNILIGEDGTIQIADFGVSAWLATGGDLSRCCVRHTFVGTPCWMAPEVMEQVHGYDFKADIWSFG ITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFF |||||||||.|||||||||||||||||||||.|||...||.|.||||.||.|... ||||||||||||.||||.||| ITAIELATGKAPYHKYPPMKVLMLTLQNDPPSLETDEDDKDMYKKYGHSFKKMIEKCLQKDPSKRPTASELLKHKFF |
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Kinase | STLK3.AA | STE20 | 75-349 | 47 | 1.7e-151 | 509.61 | In-house | 1-288 (288) | Show / Hide |
Range on Protein: 75-349 Range on HMM: 1-288/288 Sequence Identity: 47% (142 aa) YELQEVIGSGATAVVQAALCKPRQER----VAIKRINLEKCQ---TSMDELLKEIQAMSQCSHPNVVTYYTSFVVK----DELWLVMKLLSGGSMLDIIK |||.|.||.|.. .| | .|| .| ||||..|||||. ......|||. |.|| |||.|.||.|.... ||||.|| ...||| .||.| YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK YIVNRGE-HKNG-VLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLAT--GGDVTRNKVRKTFVGTPCWMAPEVMEQV ...| || | ...|. ||.|..|||.||||||.|..||||.||.||||.|||.|..|||||.| | . . | |... |.||||||.||||||.... HCMKCGKNHK-GHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGR-D-TMQFKRNTFVGTPYWMAPEVIQCM ----RGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTL--QNDPPTLE-TGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFF |||.|.| ||.||||||.|.| ||....||....... ||.||||. . .|. ..|. ....||||||.||||| .||| .|. EGPDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDD-K-----PHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI |
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Kinase | STLK3.AA | STE | 75-349 | 33 | 8.70000000001e-125 | 420.86 | In-house | 1-359 (359) | Show / Hide |
Range on Protein: 75-349 Range on HMM: 1-359/359 Sequence Identity: 33% (124 aa) YELQEVIGSGATAVVQAALCK------PRQER---------VAIKRINLEKCQ----------------TSMDELLKEIQAMSQCS--HPNVVTYYTSFV .|..|.||.||. .| |... . .| .|||..|||.|. . |...||||. |..|. |||.|.|| ... WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF VK-------DELWLVMKLLSGGSMLDIIKYIVNRGEHKN------GVLEEAIIATILKEVLEG-LDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSA .. ||||..| ...||| |||| .|. | ....| .||.|....|.| |.|||... ||||.|..|||| | ..||||.. KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG FLATGGD-----------VTRNKVRKTFVGTPCWMAPEVMEQ-----VRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQN----------- |. .. |. . |.|||||| ||||||..| . |||.|.|.||.|.|.||.||| |.|...||........| QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC ----DPPTLETGVEDKEM----------MKKYGKSFRKLLSLCLQKDPSKRPTAAELLK--CKFF .||.|.. ....|| .|. ..|. ...||||||.||||| .||| .|. IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI |
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Kinase | STLK3.AA | YSK | 75-349 | 44 | 2.1e-105 | 318.36 | In-house | 1-257 (257) | Show / Hide |
Range on Protein: 75-349 Range on HMM: 1-257/257 Sequence Identity: 44% (125 aa) YELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKY-IVNRGEHKN . ||.|| | .| . . |. |||| |.||. . . .||| ||| |.. || |. || .| . |||.|| .| | FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIEDIQQEIQFLSQCDSPYITKYYGSYLKDTKLWIIMEYCGGGSCLDLMKPKYV------- GVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVT-RNKVRKTFVGTPCWMAPEVMEQ-VRGYDFKADMWSF | ..| ||.||.|.| |||||| . |||| || |.|| |.| | ..||||. | .| . | |||||| |||||| | | .||||||.|| GQFDEKYIAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVA------GQITDTQIKRNTFVGTPYWMAPEVICQEVSYYDFKADIWSL GITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFF ||||.|.|.| || .| ||.|. | | ||.|| ..| |.| .|| |||..||.| |||| || GITAYEMAKGEPPYCDYHPMRVMFLIPKNNPPKLEG--------RSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI |
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Kinase | STLK3.AA | PAKA | 75-349 | 37 | 2.6e-82 | 279.78 | In-house | 1-260 (260) | Show / Hide |
Range on Protein: 75-349 Range on HMM: 1-260/260 Sequence Identity: 37% (107 aa) YELQEVIGSGATAVVQAALCKPRQER--VAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIV----NR |. | || ||. | | . ... ||||..|... | ... .. || | .| |.|.| |. |..|.||||.|| ..||. |.|. | YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKN-QPKKELIINEILVMKECKHKNIVNYIDSYLVDDELWVVMEYMEGGCLTDVITQCCNIQCN- GEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTR-NKVRKTFVGTPCWMAPEVMEQVRGYDFKAD ...|..|| ...|.| ||...|....||||.| ||||| |||| |.||| | | |. . |.| |||| |||||| . . || | | ------YMDEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQL------TQEQQKRNTMVGTPYWMAPEVIRR-KQYDEKVD MWSFGITAIELATGAAPYHKYPPMKVLMLTLQN-DPPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFF || || |||.. | || ..|| . . | .| |. ... | ..|.. |..||..|. .|..| |||. |. IWSLGIMAIEMIEGEPPYLNEPPLRAMYLIATNGKPDIKDP--------DKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL |
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Kinase | STLK3.AA | S_TKc | 75-349 | 30 | 2.7e-82 | 280.65 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 75-349 Range on HMM: 1-231/231 Sequence Identity: 30% (87 aa) YELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSG--GSMLDIIKYIVNRGEHK ||. ..||.|| ..| . | ...||||.|. . ...||| ... |||.|..| .|. |.|..|| ...| |...|.|| .| . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG--L NGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDF-KADMWSF . .. | .. ........|.|.|..| |||||| |||| | . |.|||....| .||.||| .|||||. ||.. |.|.||. RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------------TTFCGTPWYMAPEVL----GYGKCKCDWWSC GITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLK-------CKFF |.. .|...| |.. ..... . . .... ... ||||||.||||| |.|. .| GCILYEMLCGYPPFP--QMQMMFKKIG--------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | STLK3.AA | MST | 75-305 | 41 | 3e-73 | 232.18 | In-house | 1-217 (254) | Show / Hide |
Range on Protein: 75-305 Range on HMM: 1-217/254 Sequence Identity: 41% (97 aa) YELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFV--VKDELWLVMKLLSGGSMLDIIKYIVNRGEHK ... | .| |. .| |..| . |||| .. . . ..|..||| |.|| ...|.|| |. ..|.|| .|| .||.| | .| FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPVN---EDLQEIIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMK-ITQR---- NGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFG .| |. ||.||. .| ||.|||.| ||||.||||||| ..| ||||||. | .. | |..|||.|||||| ... .|| ||| || | --TLNEQQIACILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQL-----TDTMAKRNTVIGTPYWMAPEVIQEI-KYDCKADIWSLG ITAIELATGAAPYHKYPPMKVLMLTLQNDPPTL |||||.| | ||. || .. . |. |||. ITAIEMAEGMPPYSDIHPMRAMFMIPQKPPPTF |
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Kinase | STLK3.AA | Pkinase | 75-349 | 28 | 4e-69 | 240.76 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 75-349 Range on HMM: 1-293/293 Sequence Identity: 28% (86 aa) YELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLK---EIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGG----SMLDIIKYIVN |.. ..||||. ..| . | ...||.|.|.... ..|. . ||| | ..|||.|..| .| ||....|| .. || . |.|. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--- RGEHKNGVL--EEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSV----QIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRG ...|.. .| . .....|.||.|.|..| |||||| |||. ..| . |.|||..... .| .||.||| .||||| .. ---WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----Y-NNS-MTTFCGTPWYMAPEVIRGGQY YDFKADMWSFGITAIELATGAAPYHKY------PPMKVLMLTLQNDPPTLETGVED------------KEMMKKYGKSFRKLLSLCLQKDPSKRPTAAEL |. |.||||.|.. .|...| |. .|... .... ... . . .. .. ........ ||.|||.|||||... YGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQI LKCKFF |. ..| LQHPWF |
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Kinase | STLK3.AA | KHS | 75-349 | 40 | 6.4e-68 | 227.5 | In-house | 1-258 (258) | Show / Hide |
Range on Protein: 75-349 Range on HMM: 1-258/258 Sequence Identity: 40% (113 aa) YELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNG ||| .||| | | . .| .|.| | .| . . . .|| | .|.|||.| |. |.. .| ||..| |||. || | | YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKME-PGDDFAVIQQEIMMMKDCRHPNIVAYFGSYLRRDKLWICMEYCGGGSLQDIY--------HVTG VLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEV--MEQVRGYDFKADMWSFG |.| || . .|.|.||.||| .|..|||.| |||| ..| |..||||||| .. | .| || |.||| |||||| .|. ||. |.|. | PLSELQIAYVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITA----TIAK-RKSFIGTPYWMAPEVAAVERKGGYNQLCDIWAVG ITAIELATGAAPYHKYPPMKVLMLTLQND--PPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFF ||||||| | ||..|.| . . ||.| .||. |. ..| . . ..| |.| ||||| ||. .|. ITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKL----KDKH---KWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV |
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Kinase | STLK3.AA | SLK | 75-349 | 37 | 2.8e-66 | 222.57 | In-house | 1-259 (259) | Show / Hide |
Range on Protein: 75-349 Range on HMM: 1-259/259 Sequence Identity: 37% (105 aa) YELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNG .|. .| || |. | | .. | | |.... . ... . ||. .|.| |||.| | .. . ..||... || . |. . . WEIIGELGDGAFGKVYKAQHKEQKVFAAAKMIEIKD-EEELEDYMVEIDILSECKHPNIVKLYEAYYYDNKLWMMIEFCDGGAVDNIMVEL-------EH VLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVM--EQVRG--YDFKADMWS .|.| |. . |...|.|..||.| |||||||||||. || |..||||||| . |..| | ||.||| ||||||. | .. ||.|||.|| PLTEDQIQYVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLADFGVSAKNKH----TMQK-RDTFIGTPYWMAPEVVMCETFKDQPYDYKADIWS FGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFF .||| ||.| . |.| ||.||. . .|||||. .. |.|. .| ||.||| .|.|.|.|.. ... LGITLIEMAQMEPPHHEMNPMRVLLKIQKSEPPTLEQ-------PSHWSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV |
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Kinase | STLK3.AA | TKL | 81-345 | 22 | 1.4e-57 | 197.63 | In-house | 1-362 (364) | Show / Hide |
Range on Protein: 81-345 Range on HMM: 1-362/364 Sequence Identity: 22% (84 aa) IGSGATAVVQAALCKP--------RQERVAIKRINLEKCQTSM--------------------------DELLKEIQAMSQCSHPNVVTYYT------S- ||||. ..| . .. . . ||.|... . .. .. ... .|| ||...|||.| .. . IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG -FVVKD-----ELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNG--------QIHRDLKAGNILLGEDGS-------- .... .|..|| . .||| |... . . ... |..||| .. |||||| |||. |.. CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYN ------VQIADFGVSAFLATGGDVTRNK--------------VRKTFVGTPCWMAPEVMEQV---------------RGYDFKADMWSFGITAIELATGA . |.||| | |. . |. .... . | .|||.||||||... . |. |.|..|||| |..|. PNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRC APYHKYPPMKVL---------MLTLQND-PPTLETGVED--KEM--MKKYGKSFRKLLSLCLQKDPSKRPTAAELLK ||..||.| .. |. .. .|.. . .. | | . .|..||. | . ||.|||.. |.|| RPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHK-MCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILK |
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Kinase | STLK3.AA | PAKB | 76-349 | 37 | 2.1e-57 | 197.04 | In-house | 2-252 (252) | Show / Hide |
Range on Protein: 76-349 Range on HMM: 2-252/252 Sequence Identity: 37% (104 aa) ELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELL-KEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNG . || | | .| .| | ||.|. .| | | ||| |. | . |||.| | |. | |||| || . ||.. ||. | DNYVKIGEGSTGIVCIATEKHTGRQVAVKKMDLRKQQ--RRELLFNEVVIMRDYQHPNIVEMYSSYLVGDELWVVMEFMEGGALTDIVTHT--R------ VLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGIT ..| |||. . ||. |.||| | |||| | ||| .|| | ||| | . .| . || |||| |||||| |. ..| ||.|| -MNEEQIATVCRQVLQALAYLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSK--EVPK---RKSLVGTPYWMAPEVISRLP-YGTEVDIWSLGIM AIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFF ||. | || ||.. . . || | | . | .|. .| .||..| ||.|||. |. VIEMVDGEPPYFNEPPLQAMKRIRDMHPPRL-------KNHHKVSPRLREFLDRMLVRDPNQRWTAQELLRHPFL |
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Kinase | STLK3.AA | TyrKc | 75-349 | 22 | 4.4e-28 | 100.53 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 75-349 Range on HMM: 1-280/280 Sequence Identity: 22% (69 aa) YELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQC--SHPNVVTYYTSFVVK-------DELWLVMKLLSGGSMLDIIKYI .| ...|.|| .| . | . ||.| .. .. . ....|.. |.. .|||.| | . . . |..|| . ..|. .| ... ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH VNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATG------GDVTRNKV--RKTFVGTPCWMAPEVME .. | . . . .| .|||... ||||| | |.|.||.. | |.||| | .. . .|. | | . .. |||||.. RPK-------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI- QVRG-YDFKADMWSFGITAIELATGAAPYHKY-----PPMKVLMLTLQND--PPTLETGVEDKEMM---KKYGKSFRKLLSLCLQKDPSKRPTAAELLKC | . .| | ||||.. |. | .. . . . .. ... .| . . . | . .. . . | . ||..||| .|. . -NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY---P-MSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEI--H KFF ..| ECF |
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Kinase | STLK3.AA | Pkinase_Tyr | 75-294 | 25 | 1.1e-27 | 94.44 | Pfam | 1-225 (270) | Show / Hide |
Range on Protein: 75-294 Range on HMM: 1-225/270 Sequence Identity: 25% (60 aa) YELQEVIGSGATAVVQAALCK----PRQERVAIKRINLEKCQTS---MDELLKEIQAMSQC-SHPNVVTYYTSFV-VKDE--LWLVMKLLSGGSMLDIIK .. ...|.|| .| . .| . ||.| . |.. . ......|.. |.| .|||.| .| . .. ...|| . .|..|| . ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR YIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYD .| . .. | . . .. .|..||.... ||||| | |.|..|.. | |.||| . . . | ..|. |||||.. . . --KHR--EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYY-YRKRGGGKLPIKWMAPECINYGK-FT FKADMWSFGITAIELAT-GAAP-YHKYPPMKVL | | ||||.. |. | |. | | .. |. TKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVY |
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Kinase | STLK3.AA | MST | 326-349 | 45 | 2e-09 | 26.04 | In-house | 231-254 (254) | Show / Hide |
Range on Protein: 326-349 Range on HMM: 231-254/254 Sequence Identity: 45% (11 aa) LSLCLQKDPSKRPTAAELLKCKFF .. ||||.|..|.|| .||. |. VCKCLQKNPEQRWTAEQLLQHPFI |
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Kinase | STLK3.AA | Pkinase_Tyr | 324-349 | 30 | 0.211332 | 5.37 | Pfam | 247-270 (270) | Show / Hide |
Range on Protein: 324-349 Range on HMM: 247-270/270 Sequence Identity: 30% (8 aa) KLLSLCLQKDPSKRPTAAELLKCKFF .|. .| ..||..||| .|. .. DLMKQCWHYDPEDRPTFSEI--HEQL |
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FRWNK_Fray | STLK3.AA | FRWNK_Fray | 460-556 | 65 | 3.7e-68 | 232.76 | In-house | 1-97 (97) | Show / Hide |
Range on Protein: 460-556 Range on HMM: 1-97/97 Sequence Identity: 65% (64 aa) PCAVNLVLRLRNSRKELNDIRFEFTPGRDTADGVSQELFSAGLVDGHDVVIVAANLQKIVDDPKALKTLTFKLASGCDGSEIPDEVKLIGFAQLSVS ....|||||.||..|||||||||||||.|||.|..|||.|||||||.|.|||||||||..|.|. .|..||.|.|||...|.|||..||||||.|.. QPPINLVLRMRNQKKELNDIRFEFTPGKDTAEGIAQELVSAGLVDGRDLVIVAANLQKLIDNPQTMKSVTFQLNSGCQPNEVPDEKALIGFAQISIH |
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OSR1_C | STLK3.AA | OSR1_C | 463-494 | 36 | 1.6e-12 | 49.16 | Pfam | 1-38 (38) | Show / Hide |
Range on Protein: 463-494 Range on HMM: 1-38/38 Sequence Identity: 36% (14 aa) VNLVLRLRNSRK------ELNDIRFEFTPGRDTADGVS .||.||.|...| |...|.|||....||...|. INLWLRMRDPKKRKGKHKENEAIQFEFDIEKDTPEEVA |