VRK2

Species: Mouse
Alias: Vrk2, VRK2
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: CK1
Family: VRK

Sequence

Name Sequence Type Origin Length Description Download
VRK2.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 264 Kinase domain by global Sugen HMM Fasta, JSON
VRK2.AA Protein Sugen 503 None Fasta, JSON
VRK2.NA RNA Sugen 1906 None Fasta, JSON

Protein domain

Protein domains of VRK2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase VRK2.AA VRK 29-292 61 1.4e-204 660.35 In-house 1-284 (284) Show / Hide
Range on Protein: 29-292
Range on HMM: 1-284/284
Sequence Identity: 61% (174 aa)

WALGKMIGSGGFGLIYLAFP-TNKPN-KDARHVIKLE-YQENGPLFSELKFYQRAAKRECIQKWIQQRK------------LDYLGIPVFYGFGLTDFKG
|.|||.||.||||.||||.| |.||. |||..|.|.| ..||||||.|..|||||||.|.||||....|            |..||||...|||..||.|
WRLGKPIGQGGFGCIYLASPNTCKPCEKDAQYVVKIEPPHENGPLFTEMHFYQRAAKPEQIQKWMKKHKSLPAPQTHVLSRLPWLGIPYCWGFGYHDFNG

RSYRFMVMERLGIDLQKLLD-QNGG-FKKLTVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLDF-TNPDRVYLADYGLSYRYCPNGNHKQYQEDPRKGH
..||||||.|.|.||||... |||. |.. |||||..||||||||.||||||||||||||.||.| .|||.|||.||||.|||||||.|.||.||||..|
EKYRFMVMPRFGRDLQKIYEDQNGHRFSMKTVLQLACRMLDVLEYLHENEYVHGDIKAANILLGFEKNPDQVYLVDYGLAYRYCPNGKHRQYKEDPRRCH

NGTIEFTSLDAHKGVAPSRRSDVEILGYCMLHWLFGKLPWEAKLD--DPVAVQTAKTNLLDELPESVLKWAPSGSSCSELVKYL
|||.||||.|||||.|||||||.|||||||..||.|.|||...|.  ||..||.||....|..||...|..|....|.|..||.
NGTCEFTSMDAHKGCAPSRRSDLEILGYCMMMWLYGYLPWMDCLQQQDPEKVQDAKQKFMDNIPEMMQKCFPWKQVCCEIGKYM

Kinase VRK2.AA CK1 29-309 25 5.1e-86 292.09 In-house 1-339 (339) Show / Hide
Range on Protein: 29-309
Range on HMM: 1-339/339
Sequence Identity: 25% (86 aa)

WALGKMIGSGGFG-LIYLAFP---TNKPNK----DARHVIKLEYQ-ENGPLFSELKFYQRAAKRECIQKWIQ----QRKLDY---LGIPVFYGFGLTDFK
| ..|.||.||||  ||....   ....|.    . . ..|.|   ..|........||. .| ....|| .    . |...   .|.| .  ..   ..
WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKW-KASILKHKHFCKKHCGCPHPCMYWYHGEE

GRSYRFMVMERLGIDLQKLLD---Q-NGGFKKLTVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLDF--------------TNPDRVYLADYGLSY-RY
.. |..|||..|| .|..|..   . |. | . |.|...|.||..|||.|.. ..| |||..|....                . ..||. |.|..  .|
DDYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARRKY

CPNGNHK----------QYQEDPR----KGHNG-TIEFTSLDAHKGVAPSRRSDVEILGYCMLHWLFGK--LPWEAKLD-----DPVAVQTAKTNLLDEL
.....|.          |. . ..    ||. | |....|...|.|. ..|| |.. ..|....|| |.  |||    |     |.  |. .| .  || 
RDKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQ-VEKMKYEFIDEK

PESV-LKWAPSGS----SCSELVKYLMYVHNLAYDDKPDYQKL
. |. .. .. ..    . .|. |.. |...| |.|.|||...
KMSTPFF-LCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI

Kinase VRK2.AA CK1-A 112-309 32 1.4e-26 90.85 In-house 65-261 (261) Show / Hide
Range on Protein: 112-309
Range on HMM: 65-261/261
Sequence Identity: 32% (66 aa)

KGRSYRFMVMERLGIDLQKLLDQ-NGGFKKLTVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLDFT-NPDRVYLADYGLS--YRYCPNGNHKQYQEDPR
... |  |||. ||  |  |    .  |   ||| |   |.  .||.||  ..| |||  | |.       ...| |.||.  ||      | .|.||  
CEKDYNVMVMDLLGPSLEDLFNFCKRRFTMKTVLMLADQMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRQHIPYRED--

KGHNGTIEFTSLDAHKGVAPSRRSDVEILGYCMLHWLFGKLPWEAKLDDPVAVQTAKTNLLDELPESVLKWAPSGSSCSELVKYLMYVHNLAYDDKPDYQ
|   ||. . |..|| |.  ||| |.| .||.|. .  |||||        . .  |   . |   |.        . .|.  |. |. || ....||| 
KNLTGTARYASINAHLGIEQSRRDDMESMGYVMMYFNRGKLPWQGMK---AMTKKQKYEKISEKKMSTPIEQLCKGFPAEFCMYMNYCRNLRFEEQPDYM

KL
 |
YL

Kinase VRK2.AA CK1-Unclassified 29-250 33 2.3e-25 71.84 In-house 1-216 (244) Show / Hide
Range on Protein: 29-250
Range on HMM: 1-216/244
Sequence Identity: 33% (77 aa)

WALGKMIGSGGFGLIYLAFPTNKPNKDARHVIKLEY--QENGPLFSELKFYQRAAKRE-CIQKWIQQRKLDYLGIPVFYGFGLTDFKG--RSYRFMVMER
  ... ||.| || ||..  .|. ..     ||||   ...  |. | |..|.  ... | .          .|||  | .|    .   . | .|||. 
YRVIEKIGQGSFGEIYKC--INMQTN-EEVAIKLEKKNSKHPQLCYEAKIMQYLQNGHNC-DNF------I-KGIPKMYWCG----QEEQGDYNIMVMDL

LGIDLQKLLDQNG-GFKKLTVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLD--FTNPDRVYLADYGLSYRYC---PNGNHKQYQEDPRKGHNGTIEFT
|| .| .|.   .  |   ||| ..  |.. .||.|.. ..| |||  | |      | ..||. |.||| ||     .|.| .|.|.  |.  ||  ..
LGPSLEDLFNMCNRKFSLKTVLMIADQMIQRIEYLHNKNFIHRDIKPDNFLMGKLGKNHHQVYIIDFGLSKRYIDMDKTGKHIPYREN--KNLTGTARYA

SLDAHKGVAPSRRSDVEILGYCMLHWLFGKLPW
|. ||.|.  ||| | | |||...  | |.|||
SINAHLGIEQSRRDDLESLGYVLIYFLKGSLPW

Kinase VRK2.AA CK1 29-250 31 7.8e-25 82.55 In-house 1-216 (271) Show / Hide
Range on Protein: 29-250
Range on HMM: 1-216/271
Sequence Identity: 31% (73 aa)

WALGKMIGSGGFGLIYLAFPTNKPNK-DARHVIKL--EYQENGPLFSELKFYQRAAKRECIQKWIQQRKLDYLGIPVFYGFGLTDFKG--RSYRFMVMER
  .|. ||.| || |||.  . . .. .    |||  . ...  |  | |.|..  ...| .           |||  | .|    .   . | .|||. 
YRVGRKIGQGSFGDIYLGINM-TNGEEN-HVAIKLEKNKSKHPQLHYEAKIYKILQGHNC-DN-------QCHGIPHMYWCG----QEEQGDYNIMVMDL

LGIDLQKLLDQNG-GFKKLTVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLDF--TNPDRVYLADYGLSYRY--CPNGNHKQYQEDPRKGHNGTIEFTS
|| .| .|..  .  |   ||| ..  |.. .||.|.. ..| |||  | |      . ..||. |.||. ||    ...| .|.|.  |.  ||  ..|
LGPSLEDLFNFCNRKFSLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGRYGKHCHQVYIIDFGLAKRYRDDKTHQHIPYREN--KNLTGTARYAS

LDAHKGVAPSRRSDVEILGYCMLHWLFGKLPW
. .| |.  ||| | | |||...  | |.|||
INTHLGIEQSRRDDMESLGYVLMYFLRGSLPW

Kinase VRK2.AA TTBKL 29-190 22 3e-23 75.42 In-house 1-156 (288) Show / Hide
Range on Protein: 29-190
Range on HMM: 1-156/288
Sequence Identity: 22% (40 aa)

WALGKMIGSGGFGLIYLAFPTNKPNKDARHVIKLEYQENGPLFSELKFYQRAAKRECIQKWIQQRKLDYLG----IPVFYGFGLTDFKGRSYRFMVMERL
|   ||||.|||| .|..   .. .|. . . | |            ..... .  .... .. ... . .    .| ... | ..    .|.||||. .
WMIVKMIGEGGFGQVYHV--WDMKDKKDCAAMKEE------------KNRLEGGDSRMKMEVHVLMKLQPNGSPHFPKCHCSGKRK----DYNFMVMTLC

GIDLQKLLDQNGGFK---KLTVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLDFT---NPD--RVYLADYGLS
| .||.|  ..  .|   . |.. .||. |..| ..|.. ..| |.| .|  ....   ...  .||| |.|..
GPNLQDLRKMMPNKKRFSDGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMA

Kinase VRK2.AA CK1-D 116-250 37 2.9e-22 75.24 In-house 69-205 (261) Show / Hide
Range on Protein: 116-250
Range on HMM: 69-205/261
Sequence Identity: 37% (52 aa)

YRFMVMERLGIDLQKLLDQ-NGGFKKLTVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLDF-TNPDRVYLADYGLSYRYCPNG--NHKQYQEDPRKGHN
|  |||. ||  |  |    .  |   ||| |.  |.  .|||| ....| |||  | |.      . ||. |.||. ||       |  | |.  |   
YNVMVMDLLGPSLEDLFNYCHRKFSLKTVLMLADQMICRIEYIHCRNFIHRDIKPDNFLMGLGKRGNMVYIIDFGLAKRYRDARTHQHIPYREN--KNLT

GTIEFTSLDAHKGVAPSRRSDVEILGYCMLHWLFGKLPW
||  . |.  |.|.  ||| |.| ||| .. .  | |||
GTARYASINTHQGIEQSRRDDLESLGYVLMYFNRGSLPW

Kinase VRK2.AA Worm6 116-309 23 1.1e-13 45.71 In-house 77-279 (279) Show / Hide
Range on Protein: 116-309
Range on HMM: 77-279/279
Sequence Identity: 23% (49 aa)

YRFMVMERLGIDLQKLLDQNGGFKKLTV---LQLGIRMLDVLEYIHENEYVHGDIKAANLLLDF------TNPDRVYLADYGLSY--RYCPNGNHKQYQE
....||. .| .|. |       .|...   |...| .|. .|  | . ..| |.|..|            .  ..|. |.|..   .|| .||  . . 
FNYIVMTLVGKNLWDLRKNRP-DRKFSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKYCNKGNELRTPR

DPRKGHNGTIEFTSLDAHKGVAPSRRSDVEILGYCMLHWLFGKLPWEAKLDDPVAVQTAKTNLLDELPESVLKWAPSGSSCS-ELVKYLMYVHNLAYDDK
 .. |  ||  . .| .|||   .|. |.|   | |.... |.||| ....|. .|.  |    ... . ...    |  .  |... . |. ...| |.
WTACGFRGTVRYAPLACHKGQEQCRKDDCESWFYMMVEMIVGCLPW-RHMKDHDHVEKHKKWCRRRTRA-PMMRMFFGPCPKEEFNDIMDYIDQYSYWDR

PDYQKL
|||...
PDYKFI

Kinase VRK2.AA CK1-G 99-250 32 5.1e-12 36.93 In-house 57-208 (266) Show / Hide
Range on Protein: 99-250
Range on HMM: 57-208/266
Sequence Identity: 32% (51 aa)

GIPVFYGFGLTDFKGRSYRFMVMERLGIDLQKLLDQNG-GFKKLTVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLD---FTNPDRVYLADYGLS--YR
|||  | ||        |  |||. ||  |  | |  .  |   ||... | |.. .||.|. . . .|.|  | |       ..  ... |.|.   |.
GIPQVYYFGQCGK----YNIMVMDLLGPSLEDLFDWCDRKFSVKTVCMVAIQMIHRMEYVHSHHLIYRDVKPDNFLIGRPSNKDQHVIHIIDFGMAKQYI

YCPNGNHKQYQEDPRKGHNGTIEFTSLDAHKGVAPSRRSDVEILGYCMLHWLFGKLPW
 .  . |  | |  .|   ||  . |   | |   ||| | | ||   .  | |.|||
DPETKQHIPYRE--HKSLTGTARYMSINTHLGREQSRRDDMEALGHMFMYFLRGSLPW

Kinase VRK2.AA S_TKc 29-402 12 4.7e-11 -14.87 SMART 1-231 (231) Show / Hide
Range on Protein: 29-402
Range on HMM: 1-231/231
Sequence Identity: 12% (50 aa)

WALGKMIGSGGFGLIYLAFPTNKPNKDARHVIKLEYQENGPLFSELKFYQRAAKRECIQKWIQQRKLDYLGIPVFYGFGLTDFKGRSYRFMVMERLGI--
. ... ||.|.||  |..  ..    . .  ||                 . ..||     | ..  .   |  .|..  .     .. .|||| ..   
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK--------------EHIRREIQ---ILKK--HHPNIVKLYDVFQD-----DHLYMVMEYCDGDL

-DLQKLLDQNGG------FKKLTVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLDFTNPDRVYLADYGLSYRYCPNGNHKQYQEDPRKGHNGTIEFTSL
 || ......|.      |   ..  .   ... |||.|..  .| |.| .|.|||     .. ..| ||. ..              .   || .. . 
GDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL--------------TTFCGTPWYMAP

DAHKGVAPSR-RSDVEILGYCMLHWLFGKLPWEAKLDDPVAVQTAKTNLLDELPESVLKWAPSGSSCSELVKYLMYVHNLAYDDKPDYQKLKKILNPDGV
        .. ..|.  .| ..   | |. |..   .. .  .  .                                                      
EVL---GYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG------------------------------------------------------

PLGPLEFSTKVQSVHVRTPAQQKVDSPKATRKPANEFPAKFPKKVHRETRARQREEQEDSQPT-----MLQ----SRPAAPENSR---TRKIHEYS
                                                          ...       .||     || | |  .     |.|.. 
----------------------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase VRK2.AA TTBK 116-309 28 1.4e-10 33.59 In-house 70-257 (257) Show / Hide
Range on Protein: 116-309
Range on HMM: 70-257/257
Sequence Identity: 28% (58 aa)

YRFMVMERLGIDLQKL--LDQNGGFKKLTVLQLGIRMLDVLEYIHENEYVHGDIKAAN--LLLDFTNPDRVYLADYGLSYRYCPNGNHKQYQEDPRK--G
. .|||. .|  |  |      | |   | |.||. .|. .| ||.  . | |||  |  . .   .  ..|. |.||  .|    | .     ||.  |
FNYMVMQLQGKNLADLRRKQPRGCFSLSTTLRLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTCRKCYMLDFGLARQYT---NACGEVRPPREVAG

HNGTIEFTSLDAHKGVAPSRRSDVEILGYCMLHWLFGKLPWEAKLDDPVAVQTAKTNLLDELPESVLKWAPSGSSCSELVKYLMYVHNLAYDDKPDYQKL
  ||. . |  ||.     |. |   | | .   . | |||  |. |   |   |      .    ||  |     .|.  ..  .. | | |.|||| .
FRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVQGQLPWR-KIKDKDQVGEMKEKYDHRM---LLKHCP-----HEFHQFMDHIKSLNYEDRPDYQLI





Kinase VRK2.AA Pkinase 114-190 26 3e-06 23.24 Pfam 72-159 (293) Show / Hide
Range on Protein: 114-190
Range on HMM: 72-159/293
Sequence Identity: 26% (23 aa)

RSYRFMVMERLGI-----DLQKLLD--QNGGF--KKLTVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLD--FTNPDRVYLADYGLS
...  |||| ..      ||  ..   ..|.|     ..      .|  |||.|..  .| |.| .|.|.|   .....| ..| ||.
KDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLA

Kinase VRK2.AA CK1 286-307 40 3e-06 17.58 In-house 250-271 (271) Show / Hide
Range on Protein: 286-307
Range on HMM: 250-271/271
Sequence Identity: 40% (9 aa)

SELVKYLMYVHNLAYDDKPDYQ
.|.. || |. .| ...||||.
NEFAMYLNYCRQLHFEEKPDYM

Kinase VRK2.AA CK1-D 286-309 54 1.5e-05 15.39 In-house 238-261 (261) Show / Hide
Range on Protein: 286-309
Range on HMM: 238-261/261
Sequence Identity: 54% (13 aa)

SELVKYLMYVHNLAYDDKPDYQKL
|| ..|. |..|| .||||||  |
SEFQQYMNYCRNLKFDDKPDYCYL

Kinase VRK2.AA Worm6 29-63 34 4.2e-05 14.64 In-house 1-34 (279) Show / Hide
Range on Protein: 29-63
Range on HMM: 1-34/279
Sequence Identity: 34% (12 aa)

WALGKMIGSGGFGLIYLAFPTNKPNKDARHVIKLE
| ..| ||.|||| .|..  . . .|  . ..|.|
WKVTKKIGEGGFGAVYKVEDKSDKKK-KQFAMKCE

Kinase VRK2.AA CK1-G 287-309 39 4.2e-05 13.15 In-house 244-266 (266) Show / Hide
Range on Protein: 287-309
Range on HMM: 244-266/266
Sequence Identity: 39% (9 aa)

ELVKYLMYVHNLAYDDKPDYQKL
.. .|| || .| ....|||  |
QFATYLRYVRRLDFFECPDYDYL

Kinase VRK2.AA TyrKc 29-313 17 0.000124 -147.72 SMART 1-280 (280) Show / Hide
Range on Protein: 29-313
Range on HMM: 1-280/280
Sequence Identity: 17% (57 aa)

WALGKMIGSGGFGLIYLAFPTNKPNKDARHVIKLEYQENGPLFSELKFYQRAAKREC---IQKWIQQ----RKL--DYLGIPVFYGFGLTD---FKGRSY
  |||..|.| || .|..  .                           .| | |      ..  ..     .||  .   |  .||  ...   |     
ITLGKKLGEGAFGEVYKGTWK---------------------------IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEP

RFMVMERL-GIDLQKLLDQNGGFKKLTVLQLGIRMLDV---LEYIHENEYVHGDIKAANLLLDFTNPDRVYLADYGLSYRYCPNG-----NHKQYQEDPR
 ..|||   . ||.. |  ...   |.. .|   ....    ||.|.. ..| |. | | |..  .  .|  .| ||| |.  ..     ... |    .
LMIVMEYMPHGDLKDYLRKHRPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLS-RDIYDDDQQGESKDYYRKKEH

KGHN--GTIEFTSLDAHKGVAPSRRSDV--------EILGYCMLHWLFGKLPWEA----KLDDPVAVQTAKTNLLDELPESVLKWAPSGS----SCSELV
|| .    |  ... . .    .  |||        ||. |       |. |..     ....  ...  |.    . |....   |         .|. 
KGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTY-------GQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY---P--MSFVCCPDEMY

KYLMYVHNLAYDDKPDYQKLKKIL
.      .   .| |  . .....
QIMKQCWHEDPEDRPTFSEIHECF

Kinase VRK2.AA TTBKL 294-313 30 0.000881 8.73 In-house 269-288 (288) Show / Hide
Range on Protein: 294-313
Range on HMM: 269-288/288
Sequence Identity: 30% (6 aa)

YVHNLAYDDKPDYQKLKKIL
....| | | |||... ...
HLRSLRYYDRPDYEMIYECF

Kinase VRK2.AA CK1-D 29-45 52 0.0025 7.41 In-house 1-17 (261) Show / Hide
Range on Protein: 29-45
Range on HMM: 1-17/261
Sequence Identity: 52% (9 aa)

WALGKMIGSGGFGLIYL
. .|. |||| || ||.
YRIGRKIGSGSFGDIYH

Kinase VRK2.AA TTBK 29-44 62 0.003508 7.13 In-house 1-16 (257) Show / Hide
Range on Protein: 29-44
Range on HMM: 1-16/257
Sequence Identity: 62% (10 aa)

WALGKMIGSGGFGLIY
|   | || |||| ||
WKVVKKIGGGGFGEIY

Kinase VRK2.AA CK1-A 29-46 55 0.007866 5.63 In-house 1-18 (261) Show / Hide
Range on Protein: 29-46
Range on HMM: 1-18/261
Sequence Identity: 55% (10 aa)

WALGKMIGSGGFGLIYLA
. | . |||| || |||.
YRLVRKIGSGSFGDIYLG

Kinase VRK2.AA CK1-G 29-45 41 0.016042 4.26 In-house 1-17 (266) Show / Hide
Range on Protein: 29-45
Range on HMM: 1-17/266
Sequence Identity: 41% (7 aa)

WALGKMIGSGGFGLIYL
.. || || | || ...
YRVGKKIGCGNFGELFE

Kinase VRK2.AA Pkinase 29-46 44 0.472965 4.8 Pfam 1-18 (293) Show / Hide
Range on Protein: 29-46
Range on HMM: 1-18/293
Sequence Identity: 44% (8 aa)

WALGKMIGSGGFGLIYLA
. .|. ||||.||  |..
YHIGRKIGSGSFGCVYKC