Gene C24G6.2 (Nematode worm)
C24G6.2
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
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C24G6.2.kin_dom | Protein Kinase Domain | Sugen global kinase HMM prediction | 299 | Kinase domain by global Sugen HMM | Fasta, JSON |
C24G6.2.AA | Protein | Genbank | 903 | None | Fasta, JSON |
Protein domains of C24G6.2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | C24G6.2.AA | KIN6 | 543-841 | 57 | 4.3e-231 | 771.32 | In-house | 1-305 (305) | Show / Hide |
Range on Protein: 543-841 Range on HMM: 1-305/305 Sequence Identity: 57% (175 aa) IHNDKKLGSGAFGAVYLGKLIGKSLAHKDANSP-LGINLMRAENCQVAVKMLPEYADEMSKHEFLREIALMKTLGYHERLVNMLACVTESEPLCLVVEYC ||.|.|||.|||..||.||..|||......|.. ..|..||...||.||||||..||||..|.|..|||.||.||.|..|||||.|||.|...||||||| IHKDHKLGHGAFCNVYKGKIKGKSPIMQWINRVNMRIEMMRYQDCQCAVKMLPSHADEMAHHDFMHEIAFMKQLGHHPHLVNMLGCVTNSYKPCLVVEYC DNGDLLKFLRERCKYMMKLDDLGINYHDPPENENYDTNMIVTLKQLLQFAVQISYGLEYLSQKGFVHRDVAARNVLVHEGT---ACKIGDFGLCRYIYAD ...||||.||.||.|||.|||||||||.|.||..||..|....|.|..||.||..|.|||..|...|||.|||||||.||. .|||.|||||||.|.| CHMDLLKYLRNRCQYMMNLDDLGINYHCPDENSRYDDMMCIRHKDLYMFAWQICDGMEYLHSKNCIHRDLAARNVLVTEGCRMKTCKISDFGLCRYPYMD QSQYKSKGGK-LPLKWMSPEAIRHYEFSIKSDIWSFGILLFEVITLGGSPYPGMP-PEDVLPFLEGGGRIEKPDNCPENFYDVMMQCWNADPDDRIEFSD |.||.||||. ||.|||.||...|||||.|||.||||.|.||...||..|||.|. |.........|.|...|..|||..||.|..||...||||.||.. QFQYTSKGGRYLPIKWMAPECLKHYEFSYKSDVWSFGVLMFEMFSLGDVPYPEMQRPTEMIEHHRSGRRPKHPKWCPEEIYDIMQSCWQEKPDDRPEFNE VRMQL .|||. MRMQF |
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Kinase | C24G6.2.AA | Pkinase_Tyr | 543-841 | 41 | 2.9e-140 | 475.69 | Pfam | 1-270 (270) | Show / Hide |
Range on Protein: 543-841 Range on HMM: 1-270/270 Sequence Identity: 41% (126 aa) IHNDKKLGSGAFGAVYLGKLIGKSLAHKDANSPLGINLMRAENCQVAVKMLPEYADEMS--KHEFLREIALMKTLGYHERLVNMLACVT-ESEP--LCLV |. .||||.|||| ||.|.. | .. ....||||||.|.|.. . .|.||...||.||.|. .|......| ..|| ...| ITFGKKLGEGAFGEVYKGTWKG---------------DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIV VEYCDNGDLLKFLRERCKYMMKLDDLGINYHDPPENENYDTNMIVTLKQLLQFAVQISYGLEYLSQKGFVHRDVAARNVLVHEGTACKIGDFGLCRYIYA .||. .||||..||... . . .|.|.|||...||. |.|||..|...|||.||||.||.|. .||.||||.|.|| MEYMPHGDLLDYLRKHR----------------------EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYN DQSQ-YKSKGGKLPLKWMSPEAIRHYEFSIKSDIWSFGILLFEVITLGGSP-YPGMPPEDVLPFL-EGGGRIEKPDNCPENFYDVMMQCWNADPDDRIEF | .|..||||| |||.||.|....|..|||.||||.|..|..|.|..| ||||..|.|. .. | |.| ..|.|||. ||.|.|||..||.|| | DDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTF SDVRMQL |... || SEIHEQL |
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Kinase | C24G6.2.AA | TyrKc | 543-841 | 35 | 1.5e-129 | 437.6 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 543-841 Range on HMM: 1-280/280 Sequence Identity: 35% (118 aa) IHNDKKLGSGAFGAVYLGKLIGKSLAHKDANSPLGINLMRAENCQVAVKMLPEYADEMSKHEFLREIALMKTLG-YHERLVNMLACVTES-------EPL |. .||||.|||| ||.|... ||||||| |.| . .|.||. .|. || |. .|......|.. ||| ITLGKKLGEGAFGEVYKGTWK----------------------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPL CLVVEYCDNGDLLKFLRERCKYMMKLDDLGINYHDPPENENYDTNMIVTLKQLLQFAVQISYGLEYLSQKGFVHRDVAARNVLVHEGTACKIGDFGLCRY ..|.||...|||...||.. . ...|.||.|..||. | |||..|...||| ||||.||.|. .||.||||.|. MIVMEYMPHGDLKDYLRKHRPK-------------------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRD IYAD------QSQYKSK---GGK--LPLKWMSPEAIRHYEFSIKSDIWSFGILLFEVITLGGSPYPG-----MPPEDVLPFLEGGGRIEKPDN------- || | .. |..| ||| ||..||.||.|....|..|||.||||....|. |.|..|||| |....|. ... |.| ..|.| IYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFV -CPENFYDVMMQCWNADPDDRIEFSDVRMQL ||. |..| |||..||.|| ||... .. CCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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Kinase | C24G6.2.AA | TK | 543-841 | 25 | 5.1e-116 | 390.61 | In-house | 1-486 (486) | Show / Hide |
Range on Protein: 543-841 Range on HMM: 1-486/486 Sequence Identity: 25% (126 aa) IHNDKKLGSGAFG---AVYLGKLIGKSLAHKDANSP------LGINLMRAENCQVAVKMLPEY--ADEMSKHE--------------FLREIALMKT-LG |. ||||.|.|| ||.|...|.. . . ... | .. ....|||||| | .... ... ...|...|. || ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG YHERLVNMLACVTES------------EPLCLVVEYCDNGD----LLKFLRERCKYMMKLDDLGI-------------------------NYHDPPENEN |. .|......|.. ||...|.||...|| |...||.. ..... | . |... ||... HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPC-PEEQD YDTNMI--------------------------VTLKQLLQFAVQISYGLEYLSQK------GFVHRDVAARNVLVHEGTA-----------CKIGDFG-- ||.. | .|..||| ...||. |.|||..| .|||||.||||.||.|. |||.||| YDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS ------LCRYIYADQSQYKSK------------------------GGKLPLKWMSPEAIRHYE---------FSIKSDIWSFGILLFEVITLG-GSPYPG |.|.|| |. |... |||||..||.||.... . |..|||.||||.|..|. |.| . .|.| RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGG MPP---------EDVLPFLEGGGRI--------------EKPDNCP--------------ENFYDVMMQCWNADPDDRIEFSDVRMQL |. ..|. .|. ||| ..|..|| | .||.|.|||..||.|| ||... || MSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL |
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Kinase | C24G6.2.AA | TK-Unique | 543-841 | 35 | 2.5e-98 | 332.95 | In-house | 1-294 (294) | Show / Hide |
Range on Protein: 543-841 Range on HMM: 1-294/294 Sequence Identity: 35% (109 aa) IHNDKKLGSGAFGAVYLGKLIGKSLAHKDANSPLGINLMRAENC-QVAVKMLPEYADEMSKHEFLREIALMKTLGYHERLVNMLACVTES-EPLCLVVEY . .....|.|||| |. |.. |.. . . .|||||| ..|.. .| .||.||..|| ||.|. .|..| | |.| || ... || LEVGDVIGEGAFGQVWRGEVWGIW--------------KHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEY CDNGDLLKFLRERCKYMMKLDDLGINYH-DPPENENYDTNMIVTLKQLLQFAVQISYGLEYLSQ--KGFVHRDVAARNVLVHEGTACKIGDFGLCRYIYA | .|.|...||.. ..| . | |.. .. .. . ...|.|..||.|| |.|||.. |..||||..|||||. |. |||.|||. |..|. CPCGNLQHYLRTCRPAMRQHQ-TYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYT DQSQYKSKG-GKLPLKWMSPEAIR--HYEF-SIKSDIWSFGILLFEVITLGGSPYPGMPPEDVLPFLEGGGRIEKPDNC-PENFYDVMMQCWNADPDDRI .. . .... |..|..||.||... | . ..|||.||||.|..|. |||. ||||||..|.. .. | | ..|..| .. .| .| .||. .|..| NGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERP EFSDVRMQL |.... .| SFRQIKHRL |
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Kinase | C24G6.2.AA | Src | 585-841 | 40 | 2.5e-88 | 299.74 | In-house | 23-255 (255) | Show / Hide |
Range on Protein: 585-841 Range on HMM: 23-255/255 Sequence Identity: 40% (105 aa) NCQVAVKMLPEYADEMSKHEFLREIALMKTLGYHERLVNMLACVTESEPLCLVVEYCDNGDLLKFLRERCKYMMKLDDLGINYHDPPENENYDTNMIVTL | .|||| | . || . ||.|. .||.| ||.||...| ... || | || .| ||..|.. .. . | NTKVAVKTLKPGT--MSPEAFLQEAQIMKKL-RHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKK-----------------------DGEGRHLHL KQLLQFAVQISYGLEYLSQKGFVHRDVAARNVLVHEGTACKIGDFGLCRYIYADQSQY-KSKGGKLPLKWMSPEAIRHYEFSIKSDIWSFGILLFEVITL .||. .| |.. | .||... ..||| ||||||| |. .||..|||| | | | | ..| |.| ||. ||||.. |.|||| ||||||| |..| PQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTY GGSPYPGMPPEDVLPFLEGGGRIEKPDNCPENFYD-VMMQCWNADPDDRIEFSDVRMQL | ||||| ..|| .| | | .|.|||...|. .|.|||..||..| | . | GRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL |
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Kinase | C24G6.2.AA | UTK | 543-841 | 28 | 1e-83 | 284.4 | In-house | 1-296 (296) | Show / Hide |
Range on Protein: 543-841 Range on HMM: 1-296/296 Sequence Identity: 28% (95 aa) IHNDKKLGSGAFGAVYLGKL------IGKSLAHKDANSPLGINLMRAENCQVAVKMLPEYADEMSKH---EFLREIA---LMKTLGYHERLVNMLACVTE .. ..||.|||| |..... .... .... .. ... .. .|..| . .|| . |. ...... .| VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQ-------------------HHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQ SEPLCLVVEYCDNGDLLKFLRERCKYMMKLDDLGINYHDPPENENYDTNMIVTLKQLLQFAVQISYGLEYLSQKGFVHRDVAARNVLVHEG-------TA .||...|.||. ||||...|| . . . ..|| |.|..|..|. |..||...||||||.||||.|||. . EEPWMIVTEYMENGDLRSYLRRHRPTPP------------------ACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMV CKIGDFG---LCRYIY-------ADQSQYKSK--GGKLPLKWMSPEAIRHY-EFSIKSDIWSFGILLFEVITLGGSPYPGMPPEDVLPFLEGGG--RIEK |||.||| ..|... ..|.| . ...|..||.|||. | |..|||.||||....|. | | ||||| ..|. ... || | .. CKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPC PDNCPENFYDVMMQCWNADPDDRIEFSDVRMQL |. ||.. |..|..||..||..| | |.. |. PWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM |
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Kinase | C24G6.2.AA | SFK-Src | 683-845 | 44 | 1.1e-71 | 211.53 | In-house | 94-259 (259) | Show / Hide |
Range on Protein: 683-845 Range on HMM: 94-259/259 Sequence Identity: 44% (74 aa) TLKQLLQFAVQISYGLEYLSQKGFVHRDVAARNVLVHEGTACKIGDFGLCRYIYADQSQYKSK-GGKLPLKWMSPEAIRHYEFSIKSDIWSFGILLFEVI .. || | |. |. || . ||||| ||||||| . ||.||||. | . .|. | . | | | || ||| ||||||.||||||. |.. RMPQLVDMAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIV TLGGSPYPGMPPEDVLPFLEG--GGRIEKPDNCPENFYDVMMQCWNADPDDRIEFSDVRMQLATQL |.| ||||| || ... | | ..| |||. .| .|..|| |||| | . |. TYGRIPYPGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTFESLKWQMEDFF |
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Kinase | C24G6.2.AA | FGFR | 547-841 | 36 | 5.6e-70 | 237.7 | In-house | 5-293 (293) | Show / Hide |
Range on Protein: 547-841 Range on HMM: 5-293/293 Sequence Identity: 36% (110 aa) KKLGSGAFGAVYLGKLIGKSLAHKDANSPLGINLM-RAENCQVAVKMLPEYADEMSKHEFLREIALMKTLGYHERLVNMLACVTESEPLCLVVEYCDNGD | || |.|| | .. . || ... |||||| . . . .|.. || | |. .| | | | || .|||| | KMLGEGCFGQVWMAEAK-------------GIDCDRPEKEITVAVKMLKMNHTDKDLSDLVSEMEMMKMIGKHKNIINLLGCCTQEGPLYVIVEYCHHGN LLKFLRERCKYMMKLDDLGINYHDPPENENYDT---NMI--VTLKQLLQFAVQISYGLEYLSQKGFVHRDVAARNVLVHEGTACKIGDFGLCRYIYADQS | |||.| |. . . .| |.. .. ..| | |.| ..| |. | ||| . .||| ||||||| .. || |||| | | LRDFLRARRPPGMDYKKDSQEYTDYKPRKPEQQDDIELIPNLTQKDLVSCAYQVARGMEYLASRKCIHRDLAARNVLVTDDYVMKICDFGLARDIHCIDY QYKSKGGKLPLKWMSPEAIRHYEFSIKSDIWSFGILLFEVITLGGSPYPGMP-PEDVLPFLEGGGRIEKPDNCPENFYDVMMQCWNADPDDRIEFSDVRM | | || ||| ||| . .||.||.|.|| |. |.||.|||. | |. .| | |.||| ||... | .| ||| . |..| | . YRKTTNGRLPIKWMAPEALFDRVYTHQSDVWSYGVLLWEIMTYGGQPYPHIPSVEELYKYLKEGHRMEKPHNCSQEIYHMMCQCWHFKPCQRPTFKQLVE QL .| YL |
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Kinase | C24G6.2.AA | VEGFR | 681-841 | 40 | 5.5e-60 | 205.61 | In-house | 169-332 (332) | Show / Hide |
Range on Protein: 681-841 Range on HMM: 169-332/332 Sequence Identity: 40% (67 aa) IVTLKQLLQFAVQISYGLEYLSQKGFVHRDVAARNVLVHEGTACKIGDFGLCRY-IYADQSQYKSKGG--KLPLKWMSPEAIRHYEFSIKSDIWSFGILL ..|.. |. .. |. | |.|. . .||| ||||.|. | || |||| | || | |. ||. .||.|||.||.|. ....||.||.|..| PLTMEDLICYSFQVARGMEFLASRKCIHRDLAARNILLCENNVVKICDFGLARHGIYKDP-DYVRKGDQGRLPIKWMAPESIFDKVYTTYSDVWSYGVFL FEVITLGGSPYPGMP-PEDVLPFLEGGGRIEKPDNCPENFYDVMMQCWNADPDDRIEFSDVRMQL |. .|||||||| |. ..| | | ..|| |. |..| .|| .| | ||. | WEIFSLGGSPYPGVQIDEEFCNRLKDGYRMRAPDYCTPEIYHIMLDCWHKEPEERPHFSELVEHL |
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Kinase | C24G6.2.AA | Fer | 682-842 | 34 | 7.7e-58 | 195.56 | In-house | 108-283 (283) | Show / Hide |
Range on Protein: 682-842 Range on HMM: 108-283/283 Sequence Identity: 34% (60 aa) VTLKQLLQFAVQISYGLEYLSQKGFVHRDVAARNVLVHEGTA---CKIGDFGLCRYIYADQSQYKSK--GGKLPLKWMSPEAIRHYEFSIKSDIWSFGIL |......... |.. |.||| .|. .|||.||||.|.|.. ||| |||..| ....|| | |.| .|..||... ..| |.|.||||.. VSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTDVWSFGVM LFEVITLGGSPYPG----MPPEDV-----LPFLEGGGRIEKPDNCPENFYDVMM-QCWNADPDDRIEFSDVRMQLA ..|. | | |||| | . | ..| . |...|. .. .|| |||..||.||. ..... .| CWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK |
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Kinase | C24G6.2.AA | Abl | 687-841 | 43 | 1e-56 | 187.52 | In-house | 99-252 (252) | Show / Hide |
Range on Protein: 687-841 Range on HMM: 99-252/252 Sequence Identity: 43% (68 aa) LLQFAVQISYGLEYLSQKGFVHRDVAARNVLVHEGTACKIGDFGLCRYIYADQSQYKSKGGKLPLKWMSPEAIRHYEFSIKSDIWSFGILLFEVITLGGS ||. | ||..|..|| .. |.|||.|||| || | |. |||| | . | . | | |.|| ||.. ...||.|||.| ||.||.|. | | | LLYMATQIASGMSYLEKRHFIHRDLAARNCLVGEHHIVKVADFGLARMMKDDTYTAHA-GAKFPIKWTAPESLAYNKFSSKSDVWAFGVLLWEIATYGMS PYPGMPPEDVLPFLEGGGRIEKPDNCPENFYDVMMQCWNADPDDRIEFSDVRMQL ||||. ..| || | |.|.|. ||.. |..| |||. .. || .| .. .. PYPGIDLSHVYHKLEKGYRMERPEGCPPKVYELMRQCWQWSHTDRPSFKEIHHAM |
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Kinase | C24G6.2.AA | Pkinase | 543-832 | 21 | 3.1e-42 | 150.43 | Pfam | 1-282 (293) | Show / Hide |
Range on Protein: 543-832 Range on HMM: 1-282/293 Sequence Identity: 21% (72 aa) IHNDKKLGSGAFGAVYLGKLIGKSLAHKDANSPLGINLMRAENCQVAVKMLPEYADEMSKH-EFLR--EIALMKTLGYHERLVNMLACVTESEPLCLVVE .| .|.|||.|| ||... .| . .|||| .. ....|. . .| ||..|| |. |. | .. ..... ...| | YHIGRKIGSGSFGCVYKCHHKGTGK-------------------IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN-HPNIVRLYDWFEDKDHIYMVME YCDNG----DLLKFLRERCKYMMKLDDLGINYHDPPENENYDTNMIVTLKQLLQFAVQISYGLEYLSQKGFVHRDVAARNVLVHEGTAC----KIGDFGL ||..| || ... ...... . ... .. || ||||. ..|..|||. |.|... . ||.|||| YCEGGLYVMDLFDYIST----------------------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGL CRYIYADQSQYKSKGGKLPLKWMSPEAIR-HYEFSIKSDIWSFGILLFEVITLGGSPYPGM----PPEDVLPFLEGGGRIEKPDNCP------------- .. .. .. .. . .|.|| || . . . |.|.||.|..|.|... | |.|| . | . .. .. . . ..| AKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHW ----------ENFYDVMMQCWNADPDDRI |.. |.. |.. || .|. HFHWTFHNWSEECKDFIKWCLCKDPKKRP |
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Kinase | C24G6.2.AA | S_TKc | 543-843 | 20 | 1.4e-39 | 138.7 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 543-843 Range on HMM: 1-231/231 Sequence Identity: 20% (65 aa) IHNDKKLGSGAFGAVYLGKLIGKSLAHKDANSPLGINLMRAENCQVAVKMLPEYADEMSKHEFLREIALMKTLGYHERLVNMLACVTESEPLCLVVEYCD . .|.|.|||| ||... .. . .||.|... ..|||...| |. .|... . . . |..| |||| YEILRKIGKGAFGKVYKCRHKK-------------------TGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCD N--GDLLKFLRERCKYMMKLDDLGINYHDPPENENYDTNMIVTLKQLLQFAVQISYGLEYLSQKGFVHRDVAARNVLVHEGTACKIGDFGLCRYIYADQS . |||......| . . . . .. || .|||. ..|..|||. |.|. | ||.||||.| . GDLGDLFDYIKKRGRHGL--------------------RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----- QYKSKGGKLPLKWMSPEAIRHYEFSI-KSDIWSFGILLFEVITLGGSPYPGMPPEDVLPFLEGGGRIEKPDNCPENFYDVMMQCWNADPDDRIEFSDVRM . . .|.|| . .. |.|.||.|..|.| .. | |.| .. .. | .. . | ...|.. ||..|. .. ----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC-GYPPFP-----QMQMMFKKIG--------SPEAKDFIRKCLQKDPEKRPTA-EALQ -------QLAT DEWDIKCHPWF |
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Kinase | C24G6.2.AA | SFK-Src | 587-652 | 40 | 6.8e-13 | 33.94 | In-house | 25-87 (259) | Show / Hide |
Range on Protein: 587-652 Range on HMM: 25-87/259 Sequence Identity: 40% (27 aa) QVAVKMLPEYADEMSKHEFLREIALMKTLGYHERLVNMLACVTESEPLCLVVEYCDNGDLLKFLRE .|||| | | || |||.| ..|| | |..|. . | | ||. . | . .| || .|.| EVAVKTLKPGA--MSAEEFLQEAQVMKKL-RHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHE |
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Kinase | C24G6.2.AA | Abl | 585-652 | 44 | 1.1e-12 | 38.08 | In-house | 24-88 (252) | Show / Hide |
Range on Protein: 585-652 Range on HMM: 24-88/252 Sequence Identity: 44% (30 aa) NCQVAVKMLPEYADEMSKHEFLREIALMKTLGYHERLVNMLACVTESEPLCLVVEYCDNGDLLKFLRE .| |||| | | | | ||||.| |.|| . |. || .| | | .. |. .| || .||| DCTVAVKTLKE--DTMEVHEFLKEAAIMKEM-KHPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLRE |
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Kinase | C24G6.2.AA | VEGFR | 578-656 | 34 | 1.2e-10 | 36.51 | In-house | 21-103 (332) | Show / Hide |
Range on Protein: 578-656 Range on HMM: 21-103/332 Sequence Identity: 34% (29 aa) INLMRAENCQ-VAVKMLPEYADEMSKHEFLREIALMKTLGYHERLVNMLACVTE---SEPLCLVVEYCDNGDLLKFLRERCKY ... . |.|. |||||| | |. . . . |. ... .| | ||.| |.| || |||| | |. .|| .| FGIRKMETCTTVAVKMLKEGATASEHRALMSELKMLIHIGHHLNVVNFLGCCTKNIQKGPLMVIVEYCCFGNLSNYLRTKRMY |
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Kinase | C24G6.2.AA | Fer | 543-608 | 26 | 7.8e-09 | 26.33 | In-house | 1-58 (283) | Show / Hide |
Range on Protein: 543-608 Range on HMM: 1-58/283 Sequence Identity: 26% (19 aa) IHNDKKLGSGAFGAVYLGKLIGKSLAHKDANSPLGINLMRA-----ENCQVAVKML-PEYADEMSKHEFLRE .. .||||.|||| ||.|. . .... ... |.||.. | |... . ||..| VTLGKKLGEGAFGEVYKGR-------------R-TLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHE |
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Kinase | C24G6.2.AA | Src | 543-561 | 47 | 0.000109 | 11.8 | In-house | 1-19 (255) | Show / Hide |
Range on Protein: 543-561 Range on HMM: 1-19/255 Sequence Identity: 47% (9 aa) IHNDKKLGSGAFGAVYLGK |. .|||.| || |. |. IKLCRKLGQGQFGEVWMGY |
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Kinase | C24G6.2.AA | SFK-Src | 543-561 | 57 | 0.000182 | 8.49 | In-house | 1-19 (259) | Show / Hide |
Range on Protein: 543-561 Range on HMM: 1-19/259 Sequence Identity: 57% (11 aa) IHNDKKLGSGAFGAVYLGK | |||||| || |. |. IRLEKKLGSGQFGDVWKGR |
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Kinase | C24G6.2.AA | Fer | 632-652 | 33 | 0.0007 | 9.23 | In-house | 82-102 (283) | Show / Hide |
Range on Protein: 632-652 Range on HMM: 82-102/283 Sequence Identity: 33% (7 aa) EPLCLVVEYCDNGDLLKFLRE .|. .| |.|..|.|...|.. QPIMIVMEFCNGGSLDSYLKK |
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Kinase | C24G6.2.AA | Abl | 543-560 | 50 | 0.033863 | 2.56 | In-house | 1-18 (252) | Show / Hide |
Range on Protein: 543-560 Range on HMM: 1-18/252 Sequence Identity: 50% (9 aa) IHNDKKLGSGAFGAVYLG | .||| | .| || | IMMKHKLGGGQYGEVYEG |
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Kinase | C24G6.2.AA | VEGFR | 543-557 | 53 | 0.164417 | 1.71 | In-house | 1-15 (332) | Show / Hide |
Range on Protein: 543-557 Range on HMM: 1-15/332 Sequence Identity: 53% (8 aa) IHNDKKLGSGAFGAV .. | || |||| | LKLGKMLGRGAFGQV |