D1073.1

Species: Nematode worm
Alias: CE30924, D1073.1, aSWK407
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: X: 8952607-8945139, WormBase Genetic Map location: X:0.21,

Classification

Group: TK
Family: Trk

Sequence

Name Sequence Type Origin Length Description Download
D1073.1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 222 Kinase domain by global Sugen HMM Fasta, JSON
D1073.1.AA Protein Genbank 840 None Fasta, JSON

Protein domain

Protein domains of D1073.1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase D1073.1.AA Trk 467-738 42 4e-156 524.98 In-house 1-275 (275) Show / Hide
Range on Protein: 467-738
Range on HMM: 1-275/275
Sequence Identity: 42% (122 aa)

IEIHEMLGKGHFGEVYLAS----WDYTGPRSVAVKSIRRVDMAT----EKEARVLQDLEHPNIVKLYGMTRNNFNLLLVFEHMNHGDLKTYLEQRAPVKS
| .   || | || |.||         ..  |||| ..    .     ..||..|..|.|..|||.||.......||.|||.|.||||..||.|..|...
IVLKWELGEGAFGKVFLAECYNLCPEQDKMMVAVKTLKDASENARKDFQREAELLTNLQHQHIVKFYGVCTDHDPLLMVFEYMKHGDLNKYLRQHGPDAM

VYLQYPP-----PLVIDELKWIIKEITTGLVYLVEQSIVHRDLAARNCLVAGDSDLKATSHFERPPIRISDFGMSRRLYDHSEYYTMDHRGALPVRWLPP
.|.||.|     ||.||...||.|.|..|.||...|..||||.|.|||||......|           |.||||||..|.|..||...|...||.||.||
CYAQYQPRQAPGPLTIDQMLWIAKQIASGMVYMASQHFVHRDMATRNCLVGQNLIVK-----------IGDFGMSRDVYSHTDYYRVGHHTMLPIRWMPP

EAVQSHKFTYNSDIWSLGVTMWECMSYGRQPFDGLSNLEVSSFTLAGMR-PLKPERCPQDMYDLMVKCWHMEPVKRITAKQILEDE
|.....||||.||.||.||.||||..||.||...|||.||......|   ...|.||||..||.|..||..||..|...|.| .  
ESIMYRKFTYESDVWSFGVVMWECFTYGKQPWYQLSNHEVIECIHQGRHRLERPRRCPQEVYDIMLGCWQREPQQRMNIKDIHDII

Kinase D1073.1.AA TK 467-738 22 2.3e-90 303.09 In-house 1-486 (486) Show / Hide
Range on Protein: 467-738
Range on HMM: 1-486/486
Sequence Identity: 22% (112 aa)

IEIHEMLGKGHFG---EVYLASW----DYTGPR--------------------SVAVKSIRRVDMATEK------------------EARVLQDLE----
|.. . ||.|.||   |||.. |    .. |.|                     |||| ..  | ....                  ||.... .     
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPNIVKLYGMTRNNFN------------LLLVFEHMNHGD----LKTYLEQRAPVKSVYLQYPPP----------------------------------
 |||||.|||    . .            ...| |.|.|||    |..|| .. | .. ..  |..                                  
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LVIDELKWIIKEITTGLVYLVEQ------SIVHRDLAARNCLVAGDSDLKATSHFER--PPIRISDFGM
                               |   .|  .   |  |. || ..       .||||||||||||. .   | .  |.   | ..|.|||.
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWH--FDGCGPVCKIADFGL

S--------RRLYDHSEYYTMD-----------------------HRGALPVRWLPPEAVQSHK---------FTYNSDIWSLGVTMWECMSYGRQPFDG
|        |..|....||...                       ..| ||.||..||......         ||  ||.||.||.|||...||..|. |
SRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYG

-LSN---------LEVSSFTLAG--------------MRPLKPERCP--------------QDMYDLMVKCWHMEPVKRITAKQILEDE
 .||          ||  .  .|              ||. .|. ||              ...|||| .||| .| .| | .|..|  
GMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase D1073.1.AA Pkinase_Tyr 467-739 36 3.7e-90 305.97 Pfam 1-270 (270) Show / Hide
Range on Protein: 467-739
Range on HMM: 1-270/270
Sequence Identity: 36% (106 aa)

IEIHEMLGKGHFGEVYLASWD---YTGPRSVAVKSIRRVDMATE-------KEARVLQDL-EHPNIVKLYGMTR-----NNFNLLLVFEHMNHGDLKTYL
|.. ..||.|.|||||.. |.     .   ||||...   |  .       .||...  |  |||||.|||        |  ....|.|.| ||||..||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN--QIYIVMEYMPHGDLLDYL

EQRAPVKSVYLQYPPPLVIDELKWIIKEITTGLVYLVEQSIVHRDLAARNCLVAGDSDLKATSHFERPPIRISDFGMSRRLYDHSEYY-TMDHRGALPVR
 ..          ..|| . .|  .  .|  |. || .. ..|||||||||||.               ..|.|||..| .  . .|| .. . | ||..
RKHR-------EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE-----------NNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIK

WLPPEAVQSHKFTYNSDIWSLGVTMWECMSYGRQP-FDGLSNLEVSSFT-LAGMRPLKPERCPQDMYDLMVKCWHMEPVKRITAKQILEDEL
|..||. .  |||  ||.|| ||.||| ..||.|| . |.|| ||  .    | |  .|| ||...|||| .||| .| .| | ..|   .|
WMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEI-HEQL

Kinase D1073.1.AA TyrKc 467-739 35 1.6e-89 304.63 SMART 1-280 (280) Show / Hide
Range on Protein: 467-739
Range on HMM: 1-280/280
Sequence Identity: 35% (109 aa)

IEIHEMLGKGHFGEVYLASWDYTGPRSVAVKSIRRVDMATE---KEARVLQDL--EHPNIVKLYGMTRNN-------FNLLLVFEHMNHGDLKTYLEQRA
|.  ..|| |.|||||.. |.    . ||||...      |   .|||..  |  .|||||.|||  .           |..|.|.| ||||| ||  . 
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

PVKSVYLQYPPPLVIDELKWIIKEITTGLVYLVEQSIVHRDLAARNCLVAGDSDLKATSHFERPPIRISDFGMSRRLYDH------SEYYTM----DHRG
|           |  ..|  .   |  |  || .. ..|||||||||||. .             ..|||||.|| .||.      ..||..    . ..
PK----------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKT

ALPVRWLPPEAVQSHKFTYNSDIWSLGVTMWECMSYGRQPFDG-----LSNLEVSSFTLAGMRPLKPER--------CPQDMYDLMVKCWHMEPVKRITA
 ||.||..||. . .|||  ||.|| ||.||| ..|| ||  |     .|| ||  .  .|.|. .|.         ||..||..| .||| .| .| | 
MLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTF

KQILEDEL
..|  ...
SEI-HECF

Kinase D1073.1.AA UTK 467-738 32 9.9e-78 264.55 In-house 1-296 (296) Show / Hide
Range on Protein: 467-738
Range on HMM: 1-296/296
Sequence Identity: 32% (97 aa)

IEIHEMLGKGHFGEVYLASWD---YTGPR-SVAVKSIRRVDMATEK---------EAR---VLQDLE-HPNIVKLYGMTRNNFNLLLVFEHMNHGDLKTY
... . ||.|.||||..|...   . ..   ||||  .. ..|. .         |||   ... .. |||...|.|   .   ...| |.|  ||| .|
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LEQRAPVKSVYLQYPPPLVIDELKWIIKEITTGLVYLVEQSIVHRDLAARNCLVAGDSDLKATSHFERPPIRISDFG---MSRRLYD--------HSEYY
|   .|      . |  |  ...      |  |. || .. .||||||||||||. ..    .  ..   ..|.|||   ||||...         |.||
LRRHRPTPP---ACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRM-MWH-CMMV--CKIADFGRGGMSRRVNTFHFSNRYWESYYY

TMDHRGALPVRWLPPEAVQSH-KFTYNSDIWSLGVTMWECMSYGRQPFDGLSNLEVSSFTLAG--MRPLKPERCPQDMYDLMVKCWHMEPVKRITAKQIL
...|....|.||  |||. .| .||  ||.||.||..||....||.|. |.|| .|  . ..|   |. .|..|| ..|.||..|||..| .| ......
MAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLV

EDE
.  
QQM

Kinase D1073.1.AA TK-Unique 467-739 29 1.6e-65 223.95 In-house 1-294 (294) Show / Hide
Range on Protein: 467-739
Range on HMM: 1-294/294
Sequence Identity: 29% (89 aa)

IEIHEMLGKGHFGEVYLASWDYTG-----PRSVAVKSIRRVDMATE-----KEARVLQDLE-HPNIVKLYGMTRNNF-NLLLVFEHMNHGDLKTYLEQRA
.|. . .|.| ||.|. .    .      ...||||  ..    |.     ||..... |  |||||...| .  .. . ....|..  |.| .|| ...
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

PV-----KSVYLQ--------YPP--PLVIDELKWIIKEITTGLVYLVE--QSIVHRDLAARNCLVAGDSDLKATSHFERPPIRISDFGMSRRLYDHSEY
|.     . . |.        .|.  |.    |  ....|  |. || .  . ||||||.|||.|...           .  . |.||||.|..|.. .|
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTE-----------DKVCKICDFGMARDVYTNGVY

YTMDHRGALPVRWLPPEAVQ--SHKF-TYNSDIWSLGVTMWECMSYGRQPFDGLSNLEVSSFTLAGMRPLKPERC-PQDMYDLMVKCWHMEPVKRITAKQ
 .|. .| .|.||..||. .   . . |. ||.||.||.|||....| .|. |... ..     .|.|...|| | ...|| ||  ||. || .| .  |
SMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQ

ILEDEL
|. ..|
IK-HRL

Kinase D1073.1.AA Fer 467-739 29 1.1e-62 212.3 In-house 1-283 (283) Show / Hide
Range on Protein: 467-739
Range on HMM: 1-283/283
Sequence Identity: 29% (88 aa)

IEIHEMLGKGHFGEVYLA-SWDYTGPR---------SVAVKSIRRVDMATE------KEARVLQD-LEHPNIVKLYGMTRNNFNLLLVFEHMNHGDLKTY
......||.|.|||||.. . . .  .          |.||  .  |. .|      .|||...  . |||.||.||.      ...|.| .|.|.|..|
VTLGKKLGEGAFGEVYKGRR-TLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSY

LEQRAPVKSVYLQYPPPLVID-ELKWIIKEITTGLVYLVEQSIVHRDLAARNCLVAGDSDLKATSHFERPPIRISDFGMSRRLYDHSEYYTMD-HRGALP
| .  . |         .| | |. ... ..  |. || .. ..|||.||||||.  | . |           |||||||| . |. . |.|.     .|
L-KKNKNK---------TVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKK--------CKISDFGMSRQCSDYGYDYKMKEKACKVP

VRWLPPEAVQSHKFTYNSDIWSLGVTMWECMSYGRQPFDG------LSNL--EVSSF-TLAGMRPLKPERCPQDMYDLMV-KCWHMEPVKRITAKQILED
.|||.||..|.  .....|.|| ||..|| .. | .|. |      . |.  .     . .| ..  |...| ... .|  .||...| .|.|.|.| . 
IRWLAPETWQTGIYSPKTDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQK

EL
  
LK

Kinase D1073.1.AA CTKA 467-739 32 1.4e-58 195.45 In-house 1-290 (290) Show / Hide
Range on Protein: 467-739
Range on HMM: 1-290/290
Sequence Identity: 32% (98 aa)

IEIHEMLGKGHFGEVYLASWDYTGP---------RSVAVKSIRRVDMATEKEA-------RVLQ--DLEHPNIVKLYGMTRNNFNLLLVFEHMNHGDLKT
  |   .| ||.|.|. |      .         . ||||...  | ||| ..       .||    ..|||.. | |.      .. . |||  |||. 
HCIMFKIGEGHYGQVFRAWLMPDPDDFKAQRKKGKDVAVKMLK--DHATEEDRRAFLHEAFVLSSEHFHHPNVLRLLGVCTQHKPWHMIMEHMQYGDLHC

YLEQRAPVK----------SVYLQYPP-PLVIDELKWIIKEITTGLVYLVEQSIVHRDLAARNCLVAGDSDLKATSHFERPPIRISDFGMSRRLYDHSEY
||   .|            |.   . |  .   |  .   .|  |  || |  .||||||.||||.              . | |.||| .| |   | |
YLRACRPADGQVCPARARRSIPRSFHPIEVHAHEQVYMAMQIAAGMNYLAEMGFVHRDLACRNCLLG-----------QYCHIKIADFGHGRTLRTESQY

YTMDHRGALPVRWLPPEAVQSHKFTYNSDIWSLGVTMWECMSYGRQPFDGLSNLEVSSFTLAG-MRPLK-PERCPQDMYDLMVKCWHMEPVKRITAKQIL
|..  .. .||||  |||..  ||.  ||.|. || .|| || |  |. ..| .||    ... || |. |  ||| .| .|  ||  || .| |  ...
YYVSSQRVMPVRWMAPEALCFGKFSCASDVWAFGVLLWEIMSMGEKPWRHMSDQEVCQAYTSHGMRRLPVPRNCPQVLYHCMQECWKFEPNQRPTFETLQ

EDEL
. .|
R-ML

Kinase D1073.1.AA Musk 467-739 34 2.5e-57 187.91 In-house 1-282 (282) Show / Hide
Range on Protein: 467-739
Range on HMM: 1-282/282
Sequence Identity: 34% (102 aa)

IEIHEMLGKGHFGEVYLAS----WDYTGPRSVAVKSIR-----RVDMATEKEARVLQDLEHPNIVKLYGMTRNNFNLLLVFEHMNHGDLKTYLEQRAP--
|.    .| | || |. |.      |    .||||  .      . |  . ||  .   .||||||| |       . | || |  |||  .|  . |  
IIYVRDIGEGAFGRVFQARAPGLVPYEEETMVAVKMLKDDASKQMQMDFQREACMMAEFDHPNIVKLLGVCFVGRPMCLLFEYMAYGDLNEFLHSCSPHR

VKSVYLQYP-----------PPLVIDELKWIIKEITTGLVYLVEQSIVHRDLAARNCLVAGDSDLKATSHFERPPIRISDFGMSRRLYDHSEYYTMDHRG
. |   | .           |.|   ..  . |.|  |. || |   |||||| ||||.    | |           |.|||.||. | | .||  .   
TCSRTHQDRGMRAQVSSPGPPQLKCYHQLCMAKQIACGMAYLSEMMFVHRDLATRNCLINEHMDVK-----------IADFGLSRYIY-HQDYYKGHEND

ALPVRWLPPEAVQSHKFTYNSDIWSLGVTMWECMSYGRQPFDGLSNLEVSSFTLAGMRPLKPERCPQDMYDLMVKCWHMEPVKRITAKQILEDEL
. |.|| |||..   .||| ||.|. || .||  ||. ||. |..  ||  ..  | .   || |||..| || .||  .|  |   .|| .. .
HIPIRWMPPESIWYNQFTYESDVWAYGVCLWEIFSYALQPYYGMTHEEVIYYIRQGNILSCPENCPQKVYQLMRRCWQKNPADRPFFCQI-HHCI

Kinase D1073.1.AA InsR 467-741 33 3.5e-57 190.57 In-house 1-278 (278) Show / Hide
Range on Protein: 467-741
Range on HMM: 1-278/278
Sequence Identity: 33% (97 aa)

IEIHEMLGKGHFGEVYLA----SWDYTGPR--SVAVKSIRRVDMATEK-----EARVLQDLEHPNIVKLYGMTRNNFNLLLVFEHMNHGDLKTYLEQRAP
|..   .|.| || ||.       .  . |   .|.|..     ..|.     || |    .. ..|.|.|        . | | | .||||.||  | |
IVLIRECGQGSFGMVYEGIAKGIVPDEEWRFGRCAIKTVNENASMRERIEFLNEASVMKEFNCHHVVRLLGVCSRGQPMYVVMEMMTYGDLKSYLRSRRP

VKS-VYLQYP---PPLVIDELKWIIKEITTGLVYLVEQSIVHRDLAARNCLVAGDSDLKATSHFERPPIRISDFGMSRRLYDHSEYYTMDHRGALPVRWL
      . ..    .   |..     ||  |. ||     ||||||.|||.|..|   |           | |||| | .|.|  ||    .| ||||| 
EEEFNNPGCNRNQHVPCLDQMHQMAAEICDGMAYLAAKKFVHRDLACRNCMVNHDFTVK-----------IGDFGMTRDIYEH-DYYRKGGKGMLPVRWM

PPEAVQSHKFTYNSDIWSLGVTMWECMSYGRQPFDGLSNLEVSSFT-LAGMRPLKPERCPQDMYDLMVKCWHMEPVKRITAKQILEDELFD
.|| .   .||  ||.||.|| .||  . | ||  |||| .|  .   .|    .|| ||. ...||  ||.  |  | |...|. . | |
APESLKDGVFTTHSDVWSFGVVLWEMVTLGEQPYQGLSNEQVLKYIGMDGNVLRPPENCPEYWQELMMMCWQYQPKMRPTFLDII-HYLCD

Kinase D1073.1.AA Pkinase 467-740 24 1.3e-51 182.59 Pfam 1-293 (293) Show / Hide
Range on Protein: 467-740
Range on HMM: 1-293/293
Sequence Identity: 24% (76 aa)

IEIHEMLGKGHFGEVYLASWDYTGPRSVAVKSIRRVDMATEK--------EARVLQDLEHPNIVKLYGMTRNNFNLLLVFEHMNHG----DLKTYLEQRA
..|.. .|.| ||.||.. .  ||   |||| |....   .|        |..... | |||||.||.. ... .. .|.|....|    ||..|..   
YHIGRKIGSGSFGCVYKCHHKGTGK-IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--

PVKSVYLQYPPPL--VIDELKWIIKEITTGLVYLVEQSIVHRDLAARNCLVAGDSDLKATSHFERPPIRISDFGMSRRLYDHSEYYTMDHRGALPVRWLP
       ..  ..    .|.| ....|  || |. ...|.||||   |.|.  . ...|       ...|.||| .. .. .  .  |...   | ....
-------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA-------CVKICDFGLAKQFD-Y-NNS-MTTFCGTP-WYMA

PEAVQ-SHKFTYNSDIWSLGVTMWECMSYGRQPFDGL----SNLEVSSFTLAGMRPLKPERCP-----------------------QDMYDLMVKCWHME
|| .. . . .. .|.||.|....| .. || ||.|     . ..        |.|  .. .|                       ... |.. .|... 
PEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKD

PVKRITAKQILEDELF
| ||.||.|||... |
PKKRPTAEQILQHPWF

Kinase D1073.1.AA S_TKc 467-740 25 2.2e-49 171.3 SMART 1-231 (231) Show / Hide
Range on Protein: 467-740
Range on HMM: 1-231/231
Sequence Identity: 25% (72 aa)

IEIHEMLGKGHFGEVYLASWDYTGPRSVAVKSIRRVDMATEKEARVLQDLEHPNIVKLYGMTRNNFNLLLVFEHMNH--GDLKTYLEQRAPVKSVYLQYP
 ||.. .||| ||.||.. .     | ||.| |.     ...| ..|.   ||||||||.. ..  .| .|.|....  |||..|...| . .  .    
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK---EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF----

PPLVIDELKWIIKEITTGLVYLVEQSIVHRDLAARNCLVAGDSDLKATSHFERPPIRISDFGMSRRLYDHSEYYTMDHRGALPVRWLPPEAVQSHKFTY-
 |.   . . ....|  .| |. .. |.||||   | |.                | |.|||..|.|          .       ...|| .   .... 
-PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------------HIKICDFGLARQL----------TTFCGTPWYMAPEVL---GYGKC

NSDIWSLGVTMWECMSYGRQPFDGLSNLEVSSFTLAGMRPLKPERCPQDMYDLMVKCWHMEPVKRITAKQILE-------DELF
 .|.||.|....|... |. ||.     .   | . |         .... |.. ||....| ||.|| ..|.       .. |
KCDWWSCGCILYEMLC-GYPPFP----QMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase D1073.1.AA Ack 579-728 34 3.2e-43 143.66 In-house 114-256 (266) Show / Hide
Range on Protein: 579-728
Range on HMM: 114-256/266
Sequence Identity: 34% (53 aa)

ITTGLVYLVEQSIVHRDLAARNCLVAGDSDLKATSHFERPPIRISDFGMSRRLYDHSEYYTMDHRG--ALPVRWLPPEAVQSHKFTYNSDIWSLGVTMWE
|..|. ||  . ..|||||||| |.. |             . |.||| .|.|     ||.|  .    .|  | .||.    .|.  ||.|. |||.||
IAMGMRYLEMKRCIHRDLAARNILLFSDD----------RKVKICDFGLMRALGQNEDYYRMEFHRNLKVPFAWCAPECLRHRQFSHASDVWMFGVTLWE

CMSYGRQPFDGLSNLEVSSFTL-AGMRPLKPERCPQDMYDLMVKCWHMEPVKR
  |||..|. |.. ...      .| |  .|. ||.| |..|..||  .| .|
MFSYGEEPWAGCNGYQILQKIDKEGERLPRPDCCPEDIYQMMMQCWQHHPADR

Kinase D1073.1.AA Ror 579-728 45 4.9e-43 149.29 In-house 128-265 (308) Show / Hide
Range on Protein: 579-728
Range on HMM: 128-265/308
Sequence Identity: 45% (69 aa)

ITTGLVYLVEQSIVHRDLAARNCLVAGDSDLKATSHFERPPIRISDFGMSRRLYDHSEYYTMDHRGALPVRWLPPEAVQSHKFTYNSDIWSLGVTMWECM
|  |  ||   . ||||||||||||            |   ..||||| .|  |  | || | |.  .|.|| .|||.   ||.  ||||| ||. ||  
IAAGMEYLSSHHFVHRDLAARNCLVG-----------EHHHVKISDFGLMRDIY-SSDYYRMQHKSWMPIRWMSPEAIMYGKFSEDSDIWSFGVVLWEIW

SYGRQPFDGLSNLEVSSFTLAGMRPL--KPERCPQDMYDLMVKCWHMEPVKR
|||.||. | || ||    .   | |   |. ||. .| ||. |||  |..|
SYGMQPYYGYSNQEV--IEMIRNRHLLPCPHNCPTWIYSLMIECWHEIPSRR

Kinase D1073.1.AA Ack 467-539 32 3.3e-12 37.48 In-house 1-82 (266) Show / Hide
Range on Protein: 467-539
Range on HMM: 1-82/266
Sequence Identity: 32% (27 aa)

IEIHEMLGKGHFGEVYLASWDY-TGPR-SVAVKSIRRVDMATE-------KEARVLQDLEHPNIVKLYGMTRNNFNLLLVFE
|  .| || | || |  . |.   | . .||||. |.  |          .|. ..  |.||..|.|||  .    | .|.|
ITLCEKLGDGCFGVVWRGEWTNPGGKHIQVAVKCLRSDKMQQPNCMDDFLREVAIMHSLDHPHLVRLYGVVLDQPMLMMVTE

Kinase D1073.1.AA Ror 467-546 32 4.7e-11 40.38 In-house 1-89 (308) Show / Hide
Range on Protein: 467-546
Range on HMM: 1-89/308
Sequence Identity: 32% (30 aa)

IEIHEMLGKGHFGEVYLASWDYTGPR------SVAVKSIRRVDMAT-------EKEARVLQDLEHPNIVKLYGMTRNNFNLLLVFEHMNHGDL
..  | || . || ||  .  ..||       .||.|  .  . |.       ..|...  .|.|||||.| |   .   .. .|| ||||||
VRFMEELGECQFGKVY--KGHLMGPNFMYHCMAVAIKTCK--HDASPAQWQDFRQEIMLMATLHHPNIVCLLGVCTMDQPYCMLFEYMNHGDL