Gene gcy-19 (Nematode worm)

gcy-19

Species: Nematode worm
Alias: gcy-19, CE08279, C17F4.6, aSWK277
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: II: 3259293-3251076, WormBase Genetic Map location: n/a,

Classification

Group: RGC
Family: RGC

Sequence

Name Sequence Type Origin Length Description Download
gcy-19.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 253 Kinase domain by global Sugen HMM Fasta, JSON
gcy-19.AA Protein Genbank 1245 None Fasta, JSON

Protein domain

Protein domains of gcy-19.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
ANF_receptor gcy-19.AA ANF_receptor 104-501 17 2.1e-61 215.13 Pfam 1-364 (364) Show / Hide 
Range on Protein: 104-501
Range on HMM: 1-364/364
Sequence Identity: 17% (76 aa)

MSGGAINMAIQKLRDDGFIAPFDFEVTVNYTEC----DRSLGAAVGMEFMRTKRLDVVIGPPCRDRKSLSFRASSQFIISAMEIMATMATYYSTPMLGWG
. ..|..|||. . .|. |  ....... ...|    |   ..|......  |. ...||| |                ......| .|...  ||..||
QCAPAMRMAIEDINADPGILLPGITLGYHDDDCCYCSDC-QAVAAADCCWH-KGVVAIIGPSC---------------SYVCIPVARIANHWNIPMISWG

LVTDSKFTD--TERYPYLTNIMANSLSL-GFSLVKLLEM-MEWDRVALVYEESAQDYPLSV---INDVETAINEYDTFAVNVV-VKQALPGGDLNDAQYI
 .|.. .||   .||||........... |  .|.....   |..||..|.... .|  ..   ....... .|     .. . ...  . .| ....|.
-CTCPCLTDKAKNRYPYFFRTVPSDTYQYGWAMVDIIQHHFGWKWVAVIYDDDDYYYWRGGCYFMEAFQDELREH-GGNCVYYAYVSMVIPWDDDFMDYL

SVLNR-IKLRCRIIVSVFQTAPT---RRRYLKMIDQQGMANEEYVHILLGLRSIGFGKQSAGLTKCELNCLSSGLAPFWDIAPDDGLNDRLKQAATRMLV
..... || . |.||  .. .     .|.... . ..|| ...||.|.  . . ... |                      ..|| .||....|.  .|.
KKIKDIIKMKARVIVMCCYPDDMGLLQRQIMQQAHELGMMSGGYVWIYTDWWMHSYDMQ-W-------------------WYDDDMDNDKFREAMKGVLG

MDL-STDVPDINYLNTFTMNCGAVVVNPPVSCATPACINASTSPPSAFARSLHDVFYLYGLAITNLYNQDPAYLNDI---------DKINGALQ-LNFAG
. . . .    ... .. .                     ........|  ..| .|||. |. |. ..||.  |.          . ..  ..  || |
FTMHP-SPEFQEFMQRWKK---------------------TDTEMNYYAAYAYDAVYLYAHALHNMLRCDPNHWNGGCDIMKWHGWQLLHYMWNKVNFEG

LTGEVSINANNSRVPKLMLYALNDK
.||.|....|. |.|  |....|..
VTGDVQFDDNGGRRPDYMYWIMNWD
Kinase gcy-19.AA RGC 651-890 31 5.1e-113 381.78 In-house 1-300 (300) Show / Hide 
Range on Protein: 651-890
Range on HMM: 1-300/300
Sequence Identity: 31% (94 aa)

DKEPVLSTAHPASNLIRTDYD---TFVR---LRKLDHENVNKFVGMSIDGP------EYLAVWKLCMRGSLQDIIGQGNFSIDPFFMFCVIRDMAEGLKY
....|. . |. .||.| .     ...    .|.|.|.|.|||.||.||.|       .. ||..| |||||||. ..... | .|... |||...|. |
EGDWVWIKKHNQRNLFRHWDFTRSMMRELKQMRQLQHDNLNKFIGMCIDPPMEYHPGNMCIVWEYCSRGSLQDILENDDIKMDWMFKYSFIRDIVKGMQY

LHNSFLHVHANLRSGTVLVNESWQAKLTDFGLG----------------------TLA-EEKKPMKRRQLWMAPEVIRGTLLPHQIE---------KSAD
||.|....| ||.| . .|. .|. |.|||||.                       .  ....| ....||.|||..|....|||..         ...|
LHHSPIRYHGNLKSWNCVVDSRWVVKITDFGLNNPLCHWFKHGQINPPCKSDDKSWQRQHDEHPYYKKMLWTAPEHLREWRMPHQWGPHRQTQRGTQKGD

IYSLAVIASEVLTRKEAWNMA-----------ERKDTVDEIVYRIKKGGPNAPRPELDMDGV----EINHNLLILIRDCWSEEPADRPS-ADVICNLLKN
.||...|..|..|||..|..            .... ..|..| .||||.. .||....|      |.|. || |.||||.| |..||. .| |...||.
VYSFGIIMYEIITRKGPWDLEPFCMWPGEYELSPMEIIEEVKYPPKKGGQKPFRPSIHEDEEGHMIECNPCLLHLMRDCWAEDPEERPDMFDQIRKQLKT
Kinase gcy-19.AA RGC 651-890 31 5.1e-113 381.78 In-house 1-300 (300) Show / Hide 
Range on Protein: 651-890
Range on HMM: 1-300/300
Sequence Identity: 31% (94 aa)

DKEPVLSTAHPASNLIRTDYD---TFVR---LRKLDHENVNKFVGMSIDGP------EYLAVWKLCMRGSLQDIIGQGNFSIDPFFMFCVIRDMAEGLKY
....|. . |. .||.| .     ...    .|.|.|.|.|||.||.||.|       .. ||..| |||||||. ..... | .|... |||...|. |
EGDWVWIKKHNQRNLFRHWDFTRSMMRELKQMRQLQHDNLNKFIGMCIDPPMEYHPGNMCIVWEYCSRGSLQDILENDDIKMDWMFKYSFIRDIVKGMQY

LHNSFLHVHANLRSGTVLVNESWQAKLTDFGLG----------------------TLA-EEKKPMKRRQLWMAPEVIRGTLLPHQIE---------KSAD
||.|....| ||.| . .|. .|. |.|||||.                       .  ....| ....||.|||..|....|||..         ...|
LHHSPIRYHGNLKSWNCVVDSRWVVKITDFGLNNPLCHWFKHGQINPPCKSDDKSWQRQHDEHPYYKKMLWTAPEHLREWRMPHQWGPHRQTQRGTQKGD

IYSLAVIASEVLTRKEAWNMA-----------ERKDTVDEIVYRIKKGGPNAPRPELDMDGV----EINHNLLILIRDCWSEEPADRPS-ADVICNLLKN
.||...|..|..|||..|..            .... ..|..| .||||.. .||....|      |.|. || |.||||.| |..||. .| |...||.
VYSFGIIMYEIITRKGPWDLEPFCMWPGEYELSPMEIIEEVKYPPKKGGQKPFRPSIHEDEEGHMIECNPCLLHLMRDCWAEDPEERPDMFDQIRKQLKT
Kinase gcy-19.AA TKL 676-888 19 1.6e-31 110.79 In-house 79-364 (364) Show / Hide 
Range on Protein: 676-888
Range on HMM: 79-364/364
Sequence Identity: 19% (58 aa)

LRKLDHENVNKFVGMSIDGPE-------------YLAVWKLCMRGS-LQDIIGQGNFSIDPFFMFCVIRDMAEGLKYLHNSFL-------HVHANLRSGT
...|.|.|. .|.| ....|              .  |  .| .|| | ...        .  ..  ..|.| |. |||..          .| .| |  
MSRLRHPNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKN

VLVNESWQ--------------AKLTDFGLGTLAEEKKPMKR--------------------RQ---LWMAPEVIRGTLLPH------------QIEKSA
.||.| |.              .|..|||| .  .... |..                    .     ||||||.||..               .  ...
ILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKC

DIYSLAVIASEVLTRKEAWNMAERKDTV------DEIVYRIKKGGPNAPRPELD-----MDGVEINHNLLILIRDCWSEEPADRPSADVICNLL
|.|| ...  |.|||.. .      . .      ........|| .  . |.       ..   . . .  |. |||...| .|||.. |   |
DVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase gcy-19.AA TKL-Unique 676-821 26 8e-20 66.71 In-house 49-225 (290) Show / Hide 
Range on Protein: 676-821
Range on HMM: 49-225/290
Sequence Identity: 26% (47 aa)

LRKLD-HENVNKFVGMSI----DGPEYLAVWKLCMRGSLQDIIG---------QGNFSIDPFFMFCVIRDMAEGLKYLHNSFL-HVHANLRSGTVLVNES
. ||. |.|. ...| ..    . |..  |   | .||| | .            |  ...  .   ..|.| |. |||..     | .|.|  .||.. 
MKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNN

-----WQAKLTDFGLGTLAE--EKKPMK--------RRQ---LWMAPEVIRGTLLPHQIEKSADIYSLAVIASEVLTRK
     |..|. |||| ...    |.. .         |.   .||||||.|.     |. ...|.|| ...  | .|||
SNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNF--CQYSEKSDVYSFGIVLWEIATRK
Kinase gcy-19.AA TKL-ciliate1 786-888 24 3.5e-12 37.98 In-house 180-279 (279) Show / Hide 
Range on Protein: 786-888
Range on HMM: 180-279/279
Sequence Identity: 24% (26 aa)

WMAPEVIRGTLLP-HQIEKSADIYSLAVIASEVLTRKEAWNMAERKDTVDEIVYRIKKGGPNAP-RPEL--DMDGVEINHNLLILIRDCWSEEPADRPSA
|||||...  . |  .|   .|||...... .   ||  .   ..  ......|      .  | || |  .        |.  |. .||.. |..||..
WMAPEQMDPHIFPNYPINEKIDIYAYGIVMYILCFRKTPFQ--QKMSVINIMCYW-----CEFPGRPNLGPQFIHFDCPQNFHNLMMRCWCQNPNKRPNF

DVICNLL
. |   |
NEIIQIL
Kinase gcy-19.AA RAF 728-890 25 7.6e-12 34.39 In-house 108-282 (282) Show / Hide 
Range on Protein: 728-890
Range on HMM: 108-282/282
Sequence Identity: 25% (47 aa)

VIRDMAEGLKYLHNSFLHVHANLRSGTVLVNESWQAKLTDFGLGTLAEEKKPMKRRQ--------LWMAPEVIR------------GTLLPHQIEKSADI
. | .. |. |||     .|  |.|  ..  |  . | .|||| |.     |   .|        |||||||||               .|   .   |.
ISRQVCQGMDYLHAKNI-IHRDLKSNNIFLHEDMTVKIGDFGLMTVKTRWSPRGNQQFEQPTHWILWMAPEVIRNLMIDWRGDVLMQDENPYSFQ--SDV

YSLAVIASEVLTRKEAW--NMAERKDTVDEIVYRIKKGGPNAPRPELDMDGVEINHNLLILIRDCWSEEPADRPSADVICNLLKN
||  ..  |..||.     .  .|    | |.. .   |  . ||.|.    ..   .  |. |||. .. .||.   | . .. 
YSFGIVMYELMTRHMPYGCHIWNR----DQIIFMC---GRGYLRPDLSKVRQDCPKAMHRLMEDCWKFQREERPLFQQILKRITV
Kinase gcy-19.AA Dicty5 672-823 26 1.5e-11 35.97 In-house 48-202 (260) Show / Hide 
Range on Protein: 672-823
Range on HMM: 48-202/260
Sequence Identity: 26% (43 aa)

TFVRLRKLDHENVNKFVGMSIDGPEY-LAVWKLCMRGSLQDIIGQGNF----SIDPFFMFCVIRDMAEGLKYLHNSFLHVHANLRSGTVLVNESWQAKLT
| . . . || |. .. |       |   |  .| .||| .   .        |  |       | | ....|| |   .|  | |  .|..| |..|. 
TIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQPIAYFQQLHMAIDIAQSMRHLH-SMNIIHRDLKSMNFLITENWKIKII

DFGLGTLAEEKKPMKR---RQLWMAPEVIRGTLLPHQIEKSADIYSLAVIASEVLTRKEA
|||     . .. |      | |||.|.  |       .  .|.|| ...  |..||||.
DFGTSRFVDNRYHMTMHVGTQCWMACELFNG----QPYHQKCDVYSFGIVLWEMFTRKEP
Kinase gcy-19.AA Pkinase 755-888 16 2.2e-11 41.35 Pfam 139-293 (293) Show / Hide 
Range on Protein: 755-888
Range on HMM: 139-293/293
Sequence Identity: 16% (27 aa)

VLVNESWQA----KLTDFGLGTL--AEEKKPMKRRQ---LWMAPEVIRGTLL-PHQIEKSADIYSLAVIASEVLTRKEAWNMAE----RKDTVDEIVYRI
.|...  .     |..||||  .     .  |. .     .|||||    ..    . ...|..|. .|  |.|...  .   .    . .. .....||
ILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEV----IRGGQYYGPKVDMWSCGCILYEMLCGRPPFP-GHCWHDN-HDQMQMICRI

KKGGPNAPRPELDMDG-------------VEINHNLLILIRDCWSEEPADRPSADVICNL--L
... .  ..|...                .... ... .|..|.   |..||.|. |..   .
MGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
S_TKc gcy-19.AA S_TKc 565-892 12 4.3e-11 -14.2 SMART 1-231 (231) Show / Hide 
Range on Protein: 565-892
Range on HMM: 1-231/231
Sequence Identity: 12% (45 aa)

FAIGGVL-------IFAMLFVITCFFYVMRQKRLERDRIDAEWQIPLVKLQAPPKRDKERMSKRSLQSGPSNITDTSKMTFDNTFSNYSIFYLDKEPVLS
. |. ..        .    . |   . . . .                                                                   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------------------------------------------------------------

TAHPASNLIRTDYDTFVRLRKLDHENVNKFVGMSIDGPEYLAVWKLCMR--GSLQDIIGQGNFS-----IDPFFMFCVIRDMAEGLKYLHNSFLHVHANL
      . ||   .   .    .|.|. |. ..  |  ..  |  .|    |.| |.| . .       ...    .... ....|.|.|.    .|  |
------EHIRREIQILKK----HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDL

RSGTVLVNESWQAKLTDFGLGTLAEEKKPMKRRQL-----WMAPEVIRGTLLPHQIEK-SADIYSLAVIASEVLTRKEAWNMAERKDTVDEIVYRIKKGG
    .|..|  . |..|||| ..         . .     .|||||.       .  | ..|..|. .|  | |...  .       .....  .|.   
KPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL-------GYGKCKCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG---

PNAPRPELDMDGVEINHNLLILIRDCWSEEPADRPSADVICN-----LLKNMM
                . .. .|| |.  .|..||.|  . .      .   .
---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase gcy-19.AA MLK 675-822 23 2e-10 32.5 In-house 58-234 (291) Show / Hide 
Range on Protein: 675-822
Range on HMM: 58-234/291
Sequence Identity: 23% (43 aa)

RLRKLDHEN----VNKFVGMSIDGPE-YLAVWKLCMRGSLQDII--GQGNFS-----------IDPFFMFCVIRDMAEGLKYLHNSFLH--VHANLRSGT
.||.|.|.|    . .|.| ... |  .. |   |  ||| ...  .... .           .|. ...    ..|.|. |||.   .  .|  | |  
HLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHN

VLVNE------SWQAKLTDFGLGTLAEEK---KPMKRRQL-WMAPEVI---RGTLLPHQIEKSADIYSLAVIASEVLTRKE
.|. |        ..| .|||. .   ..   .. ..  . |||||||   |..       ...|..| .|.  |.|||..
ILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAWMAPEVIQQFRCEKY----SEKCDVWSWGVVLWEMLTREV
TyrKc gcy-19.AA TyrKc 636-888 18 9.1e-09 -80.93 SMART 1-280 (280) Show / Hide 
Range on Protein: 636-888
Range on HMM: 1-280/280
Sequence Identity: 18% (57 aa)

MTFDNTFSN------YSIFYLDKEPVL--STAHPASNLIRTDYDTFVR----LRKL--DHENVNKFVGMSIDG-------PEYLAVWKLCMRGSLQDIIG
 |.. .  .      |   .   ..|   .  . |          | |    ..||  .|.|. ...|  ...       . .. |  ..  |.|.| . 
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

QGNFSIDPFFMFCVIRDMAEGLKYLHNSFLHVHANLRSGTVLVNESWQAKLTDFGLGTLAEEK------KPMKRR----QL-------WMAPEVIRGTLL
     . .  .     . |.|  |||   . .|  |    .||.|  ..| .||||    ...      | ..|     .        |||||.|     
KHRPKLCMKDLLSFCWQIACGMEYLHSKNC-IHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-----

PHQIEKSA------DIYSLAVIASEVLTR--KEAWNMAERKDTVDEIVYRIKKGGPNAPRPE-----LDMDGVEINHNLLILIRDCWSEEPADRPSADVI
     .        |..|  |   |..|.  .  ..|.... . .|.. ..|.|.   . |.          |.    .  ....|| |.|.|||.   |
-----NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF----VCCPDEMYQIMKQCWHEDPEDRPTFSEI

CNLL
. ..
HECF
Kinase gcy-19.AA DRK 676-821 32 2.8e-08 24.2 In-house 51-199 (258) Show / Hide 
Range on Protein: 676-821
Range on HMM: 51-199/258
Sequence Identity: 32% (50 aa)

LRKLDHENVNKFVGMSIDGPEYLAVWKLCMRGSLQDIIGQGNFSIDPFFMFCVIRDMAEGLKYLHNSF-LHVHANLRSGTVLVNESWQAKLTDFGLGT--
. .| | |.  | |     |. . .     ||||  |      ..|   |     | | |. |||..    .|  | |   || |.|| |  |||| |  
MCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLMKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRF

-LAEEKKPMKRR---QLWMAPEVIRGTLLPHQIEKSADIYSLAVIASEVLTRK
   ...|  .       | |||| |        || ||.|| |..  |..||.
KKHKQHKFAMTMCGTPCWTAPEVLRNQRY---TEK-ADVYSFAIVLWECVTRQ
Kinase gcy-19.AA TK 865-888 33 4.2e-07 19.03 In-house 463-486 (486) Show / Hide 
Range on Protein: 865-888
Range on HMM: 463-486/486
Sequence Identity: 33% (8 aa)

ILIRDCWSEEPADRPSADVICNLL
.|...||...|.|||. . . . |
DLMQQCWHYDPEDRPTFSQLHEQL
Kinase gcy-19.AA MLK 858-888 29 3e-06 17.99 In-house 261-291 (291) Show / Hide 
Range on Protein: 858-888
Range on HMM: 261-291/291
Sequence Identity: 29% (9 aa)

EINHNLLILIRDCWSEEPADRPSADVICNLL
.... .  |. .||...|..||| . |   |
TCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase gcy-19.AA TK 676-793 12 6e-06 15.0 In-house 95-358 (486) Show / Hide 
Range on Protein: 676-793
Range on HMM: 95-358/486
Sequence Identity: 12% (33 aa)

LR--KLDHENVNKFVGMSIDG------------PEYLAVWKLCMRGS----LQDIIG--QGNFS------------------------------------
..  ...|.|. ...| . .|            . .. |  ..  |.    |.|      ..|.                                    
MCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPC

-------------------------------------IDPFFMFCVIRDMAEGLKYLHNSFL-----HVHANLRSGTVLVNESWQ-----------AKLT
                                     ...  .    .. |.|. |||          || .|    .||.|. .           .|..
PEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIA

DFGLGT-----LAEEKK---------------------------------PMKRRQLWMAPEVIR
||||       || .                                    .|    |||||...
DFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLN
Kinase gcy-19.AA TKL-Unique 856-888 33 3.4e-05 14.48 In-house 258-290 (290) Show / Hide 
Range on Protein: 856-888
Range on HMM: 258-290/290
Sequence Identity: 33% (11 aa)

GVEINHNLLILIRDCWSEEPADRPSADVICNLL
. ... ..  ||..||  .| .||| | | . |
PNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase gcy-19.AA DRK 866-890 40 3.7e-05 13.47 In-house 234-258 (258) Show / Hide 
Range on Protein: 866-890
Range on HMM: 234-258/258
Sequence Identity: 40% (10 aa)

LIRDCWSEEPADRPSADVICNLLKN
|. |||.|.|  ||| . .   |  
LMNDCWNEDPQHRPSMQECLERLEA
Kinase gcy-19.AA Dicty5 866-892 37 5.7e-05 13.04 In-house 234-260 (260) Show / Hide 
Range on Protein: 866-892
Range on HMM: 234-260/260
Sequence Identity: 37% (10 aa)

LIRDCWSEEPADRPSADVICNLLKNMM
||  || . |  |||   ||  .. ..
LIKKCWQQKPHNRPSFKEICKYFESII
Kinase gcy-19.AA Pkinase_Tyr 866-888 39 0.000241 15.34 Pfam 248-270 (270) Show / Hide 
Range on Protein: 866-888
Range on HMM: 248-270/270
Sequence Identity: 39% (9 aa)

LIRDCWSEEPADRPSADVICNLL
|...|| ..|.|||.   | . |
LMKQCWHYDPEDRPTFSEIHEQL
Kinase gcy-19.AA Pkinase 676-741 21 0.003101 12.52 Pfam 54-126 (293) Show / Hide 
Range on Protein: 676-741
Range on HMM: 54-126/293
Sequence Identity: 21% (16 aa)

LRKLDHENVNKFVGMSIDGPEYLAVWKLCMRG----SLQDIIG---QGNFSIDPFFMFCVIRDMAEGLKYLHN
...|.|.|. .. ..  |....  |  .|. |    .| |.|    .|.|. ..    .... ...||.|.|.
MKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHS
Kinase gcy-19.AA TKL-ciliate1 728-769 31 0.012738 4.79 In-house 108-150 (279) Show / Hide 
Range on Protein: 728-769
Range on HMM: 108-150/279
Sequence Identity: 31% (14 aa)

VIRDMAEGLKYLHNSF--LHVHANLRSGTVLVNESWQAKLTDFG
...| | |. |||     | .| .| .   |  |  | | ..|.
WCKDIAQGMQYLHMRQNPL-IHRDLKMQNILYDEPYQYKICNFP
Kinase gcy-19.AA Pkinase_Tyr 755-793 32 2.579324 1.69 Pfam 142-187 (270) Show / Hide 
Range on Protein: 755-793
Range on HMM: 142-187/270
Sequence Identity: 32% (15 aa)

VLVNESWQAKLTDFGLGTLA-------EEKKPMKRRQLWMAPEVIR
.||.|. ..| .||||  .          ..  |    |||||.|.
CLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECIN
CYCc gcy-19.AA CYCc 926-1130 41 1.9e-96 327.66 SMART 1-231 (231) Show / Hide 
Range on Protein: 926-1130
Range on HMM: 1-231/231
Sequence Identity: 41% (99 aa)

AEKKKADVLLGRMLPKQVAERLKQGQ-TVEPEGFDSVTVFFSDVVKFTQLAAKCSPFQVVNLLNDLYSNFDAIIEEHG-----CYKVESIGDGYLCVSGL
.||.|.| || .|||. ||..||||. .|.|. .|.||. |.|.| || |...|.|.||||.|||.|..|| ||..||     ||||| |||.| .|||.
MEKQKNDRLLCQMLPRHVANQLKQGRHPVWPPCYDCVTILFTDIVGFTNLCSWCTPMQVVNMLNDHYTRFDRIIDRHGCYHNYCYKVETIGDAYMVVSGC

PSKNG-------------------NAHIKQIVELSLDFMSYCKSFKIPHL----PREKVELRIGVNSGPCVAGVVGLSMPRYCLFGDTVNTASRMESNGK
|  |.                    .|...|.. .|| .. .|.|...|     | ... .|||...||.|.||||. |||||.||||||.||||||.|.
PTRNEHNQCQCLHHWWTWCFWCFHWQHAQWIADWALDMVECMKTFHVQHHMGELPWNPLRMRIGIHTGPVVCGVVGIRMPRYCYFGDTVNMASRMESTGD

GRQMALKSSSHIHLSAASYTLL-----MKHYPNQYNTAS
..|        ||.| . | .|     ... ..|...  
PGQ--------IHVSEETYWCLCLDQFERRRCGQFEFEP
Guanylate_cyc gcy-19.AA Guanylate_cyc 953-1149 39 1.2e-88 305.58 Pfam 1-214 (214) Show / Hide 
Range on Protein: 953-1149
Range on HMM: 1-214/214
Sequence Identity: 39% (88 aa)

VEPEGFDSVTVFFSDVVKFTQLAAKCS----PFQVVNLLNDLYSNFDAIIEEH--GCYKVESIGDGYLCVSGLPSK-----NGNAHIKQIVELSLDFMSY
|... .|.||..|.|.| ||.....||    |.|.|..|||.|..|| ....|  |||||. ||| |.|||||| .     .. .|. .... .||.| |
VYAQRYDCVTIMFADIVGFTAFCSRCSMNNMPMQCVRMLNDHYTCFDRLCDQHKFGCYKVKTIGDCYMCVSGLPPPCVQWCCCWHHAWCMADMALDMMEY

CKSFKIPHLPREK-----VELRIGVNSGPCVAGVVG--LSMPRYCLFGDTVNTASRMESNGKGR--QMALKSSSHIHLSAASYTLLMKHYPNQYNT--AS
|... ..|..||      ...|||...||.||||.|  ..|||||..|||||.||||||.|...  .        ||.|.. |..|..|.. |...   .
CQQVNVHHFNREPPTWNCIQMRIGIHTGPVVAGVIGSFQRMPRYCVWGDTVNVASRMESTGVPGSCK--------IHVSEETYRCLKCHENFQFECHLQH

RGDVIIKGKGV---METFWVFE
||.. .||||    |||...  
RGEIPVKGKGKMGEMETYFLHG
HNOBA gcy-19.AA HNOBA 921-947 59 1e-06 25.75 Pfam 208-234 (234) Show / Hide 
Range on Protein: 921-947
Range on HMM: 208-234/234
Sequence Identity: 59% (16 aa)

TKELTAEKKKADVLLGRMLPKQVAERL
..||  |||| | ||  |.||.||.||
HRELEEEKKKTDDLLYSMFPKSVANRL