Gene gcy-5 (Nematode worm)

gcy-5

Species: Nematode worm
Alias: ZK970.6, aSWK295, gcy-5, CE02406
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: II: 10316121-10310302, WormBase Genetic Map location: n/a,

Classification

Group: RGC
Family: RGC

Sequence

Name Sequence Type Origin Length Description Download
gcy-5.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 256 Kinase domain by global Sugen HMM Fasta, JSON
gcy-5.AA Protein Genbank 1122 None Fasta, JSON

Protein domain

Protein domains of gcy-5.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
ANF_receptor gcy-5.AA ANF_receptor 48-426 18 4.4e-68 237.28 Pfam 1-364 (364) Show / Hide 
Range on Protein: 48-426
Range on HMM: 1-364/364
Sequence Identity: 18% (75 aa)

SCGGTLPIAVQYLKSKGF--LTDFDVEYYMEYTE--CDRASVAKAGMKFMKEMNVDVVVGPSCGDALAIMGTLSAIYKKLVLGWGFVSDTQLAD--TNRF
 |.. ...|........   |......|.. ...  .|    . |......  .|....|||| .. .... . . ... ...|| .... | |   ||.
QCAPAMRMAIEDINADPGILLPGITLGYHDDDCCYCSDC-QAVAAADCCWH-KGVVAIIGPSCSYVCIPVARIANHWNIPMISWG-CTCPCLTDKAKNRY

PYVASVQPTAQTL-GLATSRILEM-FQFDRVALLYYKDDQDYCKSV---MDDVEATLSDPDLYPVRI--VWKGELQSDNEALTRSTLQA-VKSRARIVLL
||.. . |..  . | | ..|... |. ..||..|..|| .|. ..   |.... .| .. .. |..  | . . ..|...   . ..  .|..||....
PYFFRTVPSDTYQYGWAMVDIIQHHFGWKWVAVIYDDDDYYYWRGGCYFMEAFQDELREHGGNCVYYAYVSMVIPWDDDFMDYLKKIKDIIKMKARVIVM

CAISGPE---KRNYLISIAQQNMTTNEYVHILLTMRSIGYGVQTSLGKKTFANGLTPLWESFTVAPDGNETNARRAAEKMLVIDVNSDVQDAEFLQYLTK
|. .      .| ... .....|.. .||.|. .. . .|..| .                   ..|  .. . |.| |. ...    . . || .....
CCYPDDMGLLQRQIMQQAHELGMMSGGYVWIYTDWWMHSYDMQ-W------------------WYDDDMDNDKFREAMKGVLGFTMH-P-SPEFQEFMQR

NIADAVRNPPMKCNTSECINASSTSMGSYARHLFDVFYLYGMAVSKLNSTDPTVYGNL---------NLLMPQMV-TSFDGMTGRVQIGQNLYRVPTYQL
. .                  ..|.| .|| ...| .|||..|. .....|| ..  .         .||      ..|.|.||.||.  |  |.| |..
WKK------------------TDTEMNYYAAYAYDAVYLYAHALHNMLRCDPNHWNGGCDIMKWHGWQLLHYMWNKVNFEGVTGDVQFDDNGGRRPDYMY

YGLDEK
. .. .
WIMNWD
Kinase gcy-5.AA RGC 577-815 35 2.1e-125 422.89 In-house 1-300 (300) Show / Hide 
Range on Protein: 577-815
Range on HMM: 1-300/300
Sequence Identity: 35% (105 aa)

EKDLVLTTKHHSM----QMNK--EEKEKFVKLRKLEHDNLNKFIGLSIDGP------QFVAVWKMCSRGSLQDIIARGNFSMDGFFMFCIITDIAEGMNF
|.|.|...||. .    . .   ... .. ..|.|.|||||||||..||.|      ... ||..|||||||||.......|| .|... |.||..||..
EGDWVWIKKHNQRNLFRHWDFTRSMMRELKQMRQLQHDNLNKFIGMCIDPPMEYHPGNMCIVWEYCSRGSLQDILENDDIKMDWMFKYSFIRDIVKGMQY

LHKSFLHLHGNLRSATCLVNDSWQVKLTDFGLG----------------------ALL-EEHTPSKKRLLWAAPEVLRGSLTIHQMD---------PSAD
||.|... ||||.|..|.|...|.||.|||||.                       .  ....|..|..|| |||.||.... ||..         ...|
LHHSPIRYHGNLKSWNCVVDSRWVVKITDFGLNNPLCHWFKHGQINPPCKSDDKSWQRQHDEHPYYKKMLWTAPEHLREWRMPHQWGPHRQTQRGTQKGD

VYSFAIIASEILTKREAWDIS-----------NRKEGADEILYMVKKGGNRTIRPELILD-----AEVSPRLTTLVKDCWSEQPEDRPK-AEQICKLLSE
||||.||..||.|....||..           ...| ..|..|..||||....||... |     .|. |.| .|..|||.|.||.||  ..||.|.|..
VYSFGIIMYEIITRKGPWDLEPFCMWPGEYELSPMEIIEEVKYPPKKGGQKPFRPSIHEDEEGHMIECNPCLLHLMRDCWAEDPEERPDMFDQIRKQLKT
Kinase gcy-5.AA RGC 577-815 35 2.1e-125 422.89 In-house 1-300 (300) Show / Hide 
Range on Protein: 577-815
Range on HMM: 1-300/300
Sequence Identity: 35% (105 aa)

EKDLVLTTKHHSM----QMNK--EEKEKFVKLRKLEHDNLNKFIGLSIDGP------QFVAVWKMCSRGSLQDIIARGNFSMDGFFMFCIITDIAEGMNF
|.|.|...||. .    . .   ... .. ..|.|.|||||||||..||.|      ... ||..|||||||||.......|| .|... |.||..||..
EGDWVWIKKHNQRNLFRHWDFTRSMMRELKQMRQLQHDNLNKFIGMCIDPPMEYHPGNMCIVWEYCSRGSLQDILENDDIKMDWMFKYSFIRDIVKGMQY

LHKSFLHLHGNLRSATCLVNDSWQVKLTDFGLG----------------------ALL-EEHTPSKKRLLWAAPEVLRGSLTIHQMD---------PSAD
||.|... ||||.|..|.|...|.||.|||||.                       .  ....|..|..|| |||.||.... ||..         ...|
LHHSPIRYHGNLKSWNCVVDSRWVVKITDFGLNNPLCHWFKHGQINPPCKSDDKSWQRQHDEHPYYKKMLWTAPEHLREWRMPHQWGPHRQTQRGTQKGD

VYSFAIIASEILTKREAWDIS-----------NRKEGADEILYMVKKGGNRTIRPELILD-----AEVSPRLTTLVKDCWSEQPEDRPK-AEQICKLLSE
||||.||..||.|....||..           ...| ..|..|..||||....||... |     .|. |.| .|..|||.|.||.||  ..||.|.|..
VYSFGIIMYEIITRKGPWDLEPFCMWPGEYELSPMEIIEEVKYPPKKGGQKPFRPSIHEDEEGHMIECNPCLLHLMRDCWAEDPEERPDMFDQIRKQLKT
Kinase gcy-5.AA TKL 587-813 22 4.9e-36 126.04 In-house 64-364 (364) Show / Hide 
Range on Protein: 587-813
Range on HMM: 64-364/364
Sequence Identity: 22% (68 aa)

HSMQMNKEEKEKFVKLRKLEHDNLNKFIGLSIDGPQ-------------FVAVWKMCSRGSLQDIIARGNFSMDGFFMFCIITDIAEGMNFLHKSFL---
........|.|  . ...| |.|. .|.| ....|.             .  |   |..||| ...           .. .. ||| |||.|| .     
EASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWC

----HLHGNLRSATCLVNDSWQ--------------VKLTDFGLGALLEEHTP--------------------SKKRL---LWAAPEVLRGSL-TIH---
     .| .| |. .||.. |.              .|..||||   .....                     . ..     | |||||||.. . .   
TKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVG

--------QMDPSADVYSFAIIASEILTKREAWD--ISNRKEGA---DEILYMVKKGGNRTIRPELILD-------AEVSPRLTTLVKDCWSEQPEDRPK
        . ....|||||.|.  |||| .. ..   ..  ...   .|...|| . |.|  .|.  ..         . |..  | .|||.. ||.|| 
IDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPS

AEQICKLL
...| | |
FQEILKRL
Kinase gcy-5.AA TK 584-813 14 1.7e-21 68.16 In-house 59-486 (486) Show / Hide 
Range on Protein: 584-813
Range on HMM: 59-486/486
Sequence Identity: 14% (61 aa)

TKHHSMQMNKEEKEK-----------------FVKLRK---LEHDNLNKFIGLSIDG------------PQFVAVWKMCSRGS----LQDIIA--RGNFS
...    |..||..                    |. .   ..|.|. ...| . .|            . .  |  ... |.    |.|     |..|.
MLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQ

-------------------------------------------------------------------------MDGFFMFCIITDIAEGMNFLHKSFL--
                                                                         ..   .  .  .||.|| .||.     
HEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEF

---HLHGNLRSATCLVNDSWQ-----------VKLTDFG--------LGALL---EEHTPSK------------------------KRLL---WAAPEVL
     |..|    |||... .           .|..|||        |   .   .. . ..                        .. |   | |||.|
IQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECL

R-GSLTIH----QMDPSADVYSFAIIASEILT---KREAWDISNRKEGA----DEILYMVKKG-----------GNRTIRP--ELILD---------AEV
. .  . .       .  ||.|| .   ||.|   .  ....||..  .    .|.. ....|           |.|  .|  ..  |          . 
NDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCP

SPRLTTLVKDCWSEQPEDRPKAEQICKLL
 . .  | ..||...|||||  .|. . |
PEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase gcy-5.AA TKL-Unique 602-745 27 1.3e-19 66.01 In-house 49-223 (290) Show / Hide 
Range on Protein: 602-745
Range on HMM: 49-223/290
Sequence Identity: 27% (48 aa)

LRKLE-HDNLNKFIGLSI----DGPQFVAVWKMCSRGSLQDIIA---------RGNFSMDGFFMFCIITDIAEGMNFLHKSFL-HLHGNLRSATCLVNDS
. ||. |.|. ...| ..    . |..  |   |..||| | ..         . |  ..   .  .. ||| ||..|| .    .|..|.|   ||.  
MKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNN

-----WQVKLTDFGLGALLEEHTPSKKR-------------LLWAAPEVLRGSLTIHQMDPSADVYSFAIIASEILT
     |..|. ||||  ..   . ....             ..|.||||||..    | . ..|||||.|.  ||.|
SNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNF--CQYSEKSDVYSFGIVLWEIAT
Kinase gcy-5.AA MLK 601-813 21 1.7e-17 57.34 In-house 58-291 (291) Show / Hide 
Range on Protein: 601-813
Range on HMM: 58-291/291
Sequence Identity: 21% (52 aa)

KLRKLEHDN----LNKFIGLSIDGPQ-FVAVWKMCSRGSLQDIIARGN-------------FSMDGFFMFCIITDIAEGMNFLHKSFLH--LHGNLRSAT
.||.| | |      .| | ... |. |. |   |. ||| .... ..             . .|  ... . ...|.||..||.   .   |  | |  
HLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHN

CLVND------SWQVKLTDFGLGALLEEHTPS---KKR--LLWAAPEVL---RGSLTIHQMDPSADVYSFAIIASEILTKREAWDISNRKEGADEILYMV
 |. .        ..| .|||.   . ... .   ...  . | ||||.   |..    . . ..||.|....  |.||...  .  .  ...  . ...
ILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTYAWMAPEVIQQFRCE----KYSEKCDVWSWGVVLWEMLTREVPYK--QHYDPMAIAWWVA

KKGGNRTIRPELILDAEVSPRLTTLVKDCWSEQPEDRPKAEQICKLL
 .| ...|...       ....  | |.||.. |..||.  || . |
YNGLRPPIPST------CPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase gcy-5.AA RAF 654-815 28 1.7e-17 53.01 In-house 108-282 (282) Show / Hide 
Range on Protein: 654-815
Range on HMM: 108-282/282
Sequence Identity: 28% (52 aa)

IITDIAEGMNFLHKSFLHLHGNLRSATCLVNDSWQVKLTDFGLGALLEEHT--------PSKKRLLWAAPEVLR-------GSLTIHQMDP---SADVYS
|   .. ||..||.    .|  |.|   .  .  .|| .||||  .    .              || |||| |       | . .    |     ||||
ISRQVCQGMDYLHAKNI-IHRDLKSNNIFLHEDMTVKIGDFGLMTVKTRWSPRGNQQFEQPTHWILWMAPEVIRNLMIDWRGDVLMQDENPYSFQSDVYS

FAIIASEILTKREAW--DISNRKEGADEILYMVKKGGNRTIRPEL-ILDAEVSPRLTTLVKDCWSEQPEDRPKAEQICKLLSE
| |.  |..|..     .|.||    | |..|.   |   .||.|  .  ..   .  |..|||. |.|.||  .|| | .  
FGIVMYELMTRHMPYGCHIWNR----DQIIFMC---GRGYLRPDLSKVRQDCPKAMHRLMEDCWKFQREERPLFQQILKRITV
Kinase gcy-5.AA DRK 631-745 36 8.3e-13 39.75 In-house 80-197 (258) Show / Hide 
Range on Protein: 631-745
Range on HMM: 80-197/258
Sequence Identity: 36% (45 aa)

SRGSLQDIIARGNFSMDGFFMFCIITDIAEGMNFLHKSF-LHLHGNLRSATCLVNDSWQVKLTDFGLGA---LLEEHTPSKKRL---LWAAPEVLRGSLT
.||||  |      .||   |  .  |.| ||..|| .    .|  | |   || ..||||  ||||       ..|.  .       | ||||||    
PRGSLYNILHDESIEMDWPLMKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLRN---

IHQMDPSADVYSFAIIASEILT
       ||||||||.  |..|
-QRYTEKADVYSFAIVLWECVT
Kinase gcy-5.AA Dicty4 657-748 37 3.7e-12 37.01 In-house 120-215 (277) Show / Hide 
Range on Protein: 657-748
Range on HMM: 120-215/277
Sequence Identity: 37% (38 aa)

DIAEGMNFLHK-S--FLHLHGNLRSATCLVNDSWQVKLTDFGLGALLEEHTPSKK-------RLLWAAPEVLRGSLTIHQMDPSADVYSFAIIASEILTK
|.| ||| ||     ..|.   | |.  || ..|.|| .|||| ..  .|.  |          .| ||||...    .  . .||||||.|.  ||||.
DAARGMNWLHCCNPVIIHR--DLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMH----QPYNEKADVYSFGIVLWEILTR

RE
 |
QE
S_TKc gcy-5.AA S_TKc 557-817 18 6.3e-11 -16.7 SMART 1-231 (231) Show / Hide 
Range on Protein: 557-817
Range on HMM: 1-231/231
Sequence Identity: 18% (51 aa)

GESKMTI-DGGFHENYTVQMFEKDLVLTTKHHSMQMNKEEKEKFVKLRKLEHDNLNKFIGLSIDGPQFVAVWKMCSR--GSLQDIIARGNFS-----MDG
 |   .|  |.| . | ..  . . .   |  .   .. ..|  .  .   |.|. |...   |   .  |  .|.   |.| |.| . .       .. 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE

FFMFCIITDIAEGMNFLHKSFLHLHGNLRSATCLVNDSWQVKLTDFGLGALLEEHTPSKKRLLWAAPEVLRGSLTIHQMDP-SADVYSFAIIASEILTKR
    ...  |.......|.    .|  |  .  |...  ..|..|||| ..|   |     . . |||||       . .. ..|..|. .|  | |. .
-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL---TTFCGTPWYMAPEVL-------GYGKCKCDWWSCGCILYEMLCGY

EAWDISNRKEGADEILYMVKKGGNRTIRPELILDAEVSPRLTTLVKDCWSEQPEDRPKAEQICK-----LLSEMT
  ..         ..  | || |              || .  ... |.   ||.|| | .. .      . .  
PPFP---------QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
TyrKc gcy-5.AA TyrKc 576-813 21 6.4e-11 -46.13 SMART 1-280 (280) Show / Hide 
Range on Protein: 576-813
Range on HMM: 1-280/280
Sequence Identity: 21% (65 aa)

FEKDLVL--------------------TTKHHSMQMNKEEKEKFVK----LRKL--EHDNLNKFIGLSIDG-------PQFVAVWKMCSRGSLQDII--A
 ... .|                    . |...       .| | .    ..||  .|.|. ...|  ...       ..   |   .. |.|.| .   
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

RGNFSMDGFFMFCIITDIAEGMNFLHKSFLHLHGNLRSATCLVNDSWQVKLTDFGLGALLEEH----------TP----SKKRLL---WAAPEVLRGSLT
|....|. .  ||.  .||.||..||.  .  |  |    |||..  .|| .||||   ....          ..    ..| .|   | |||..     
RPKLCMKDLLSFCW--QIACGMEYLHSKNC-IHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI----N

IHQMDPSADVYSFAIIASEILT--KREAWD-----ISNRKEGADEILYMVKKGGNRTIRPELILDAE-----VSPRLTTLVKDCWSEQPEDRPKAEQICK
 .   .  ||.|| .   ||.|  .   ..     .||.     |..  ||.| .|  .|. ..  .      .. . .. |.|| |.|||||  ..|..
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQ-----EVIEYVKQG-YRMPQPPNDY--PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHE

LL
..
CF
Kinase gcy-5.AA Dicty5 731-817 32 2.3e-10 31.89 In-house 184-260 (260) Show / Hide 
Range on Protein: 731-817
Range on HMM: 184-260/260
Sequence Identity: 32% (28 aa)

ADVYSFAIIASEILTKREAWDISNRKEGADEILYMVKKGGNRTIRPELILDAEVSPRLTTLVKDCWSEQPEDRPKAEQICKLLSEMT
.|||||.|.  |..|. |. |  |.     .|  || ||.    ||.  . . .      |.| || . |  ||    ||| .  . 
CDVYSFGIVLWEMFTRKEPYDNINNW----NIPVMVMKGE----RPT--IPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII
Kinase gcy-5.AA Pkinase 681-813 17 5.6e-10 36.35 Pfam 139-293 (293) Show / Hide 
Range on Protein: 681-813
Range on HMM: 139-293/293
Sequence Identity: 17% (29 aa)

CLVNDSWQV----KLTDFGLGALLEEHTPSKKR------LLWAAPEVLRGSLTIHQMDPSADVYSFAIIASEILTKREAWDISN----RKEGADEILYMV
.|...  ..    |..|||| .... . ..         . ..||||.|   .    .|..|..|. .|  | |..|  .. .     .    .......
ILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIR---GGQYYGPKVDMWSCGCILYEMLCGRPPFP-GHCWHDN-HDQMQMICRI

KKGGNRTIRPELILDA--------------EVSPRLTTLVKDCWSEQPEDRPKAEQICKL--L
... ..  .|...                 ..|. .  ..|.|.   |..|| ||||..   .
MGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase gcy-5.AA DRK 782-815 29 1.8e-07 21.38 In-house 225-258 (258) Show / Hide 
Range on Protein: 782-815
Range on HMM: 225-258/258
Sequence Identity: 29% (10 aa)

AEVSPRLTTLVKDCWSEQPEDRPKAEQICKLLSE
. ..|  . | .|||.| |  ||  ... . |  
QWCPPKYIQLMNDCWNEDPQHRPSMQECLERLEA
Kinase gcy-5.AA Dicty4 782-815 27 2.3e-07 20.81 In-house 242-277 (277) Show / Hide 
Range on Protein: 782-815
Range on HMM: 242-277/277
Sequence Identity: 27% (10 aa)

AEVSPRLTTLVKDCWSEQPEDRPKAEQICKL--LSE
. ..|....|...||.. |. ||  |.| .   | .
DWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase gcy-5.AA Dicty5 657-695 41 1.5e-05 15.1 In-house 112-149 (260) Show / Hide 
Range on Protein: 657-695
Range on HMM: 112-149/260
Sequence Identity: 41% (16 aa)

DIAEGMNFLHKSFLHLHGNLRSATCLVNDSWQVKLTDFG
||| .| .|| |    |  | |   |..  |..|. |||
DIAQSMRHLH-SMNIIHRDLKSMNFLITENWKIKIIDFG
Kinase gcy-5.AA Pkinase_Tyr 785-813 37 0.000118 16.39 Pfam 242-270 (270) Show / Hide 
Range on Protein: 785-813
Range on HMM: 242-270/270
Sequence Identity: 37% (11 aa)

SPRLTTLVKDCWSEQPEDRPKAEQICKLL
.. . .| |.|| ..|||||  ..|   |
PDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase gcy-5.AA TKL-Unique 786-813 28 0.000138 12.3 In-house 263-290 (290) Show / Hide 
Range on Protein: 786-813
Range on HMM: 263-290/290
Sequence Identity: 28% (8 aa)

PRLTTLVKDCWSEQPEDRPKAEQICKLL
.... | ..||  .|..||  ..| . |
KEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase gcy-5.AA Pkinase_Tyr 651-696 34 0.003017 11.62 Pfam 113-157 (270) Show / Hide 
Range on Protein: 651-696
Range on HMM: 113-157/270
Sequence Identity: 34% (16 aa)

MFCIITDIAEGMNFLHKSFLHLHGNLRSATCLVNDSWQVKLTDFGL
. .. ..||.||..|.   .  |  |.   |||... .|| .||||
LLQMCWQIAKGMEYLESKNC-IHRDLAARNCLVTENNVVKICDFGL
Kinase gcy-5.AA Pkinase 602-667 21 5.994136 0.9 Pfam 54-126 (293) Show / Hide 
Range on Protein: 602-667
Range on HMM: 54-126/293
Sequence Identity: 21% (16 aa)

LRKLEHDNLNKFIGLSIDGPQFVAVWKMCSRG----SLQDIIA---RGNF--SMDGFFMFCIITDIAEGMNFLHK
...| |.|  ....   |..    |   |  |    .| |.|    .|.|  |..     .... |..|....|.
MKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWE--CKFYMYQILRGLEYCHS
CYCc gcy-5.AA CYCc 852-1048 44 9.60000000001e-105 355.2 SMART 1-231 (231) Show / Hide 
Range on Protein: 852-1048
Range on HMM: 1-231/231
Sequence Identity: 44% (102 aa)

LEKKKADILLSRMLPKQVAERLKAGQ-TVEPEGFDTVTVLFSDVVKFTQLAAKCSPFQVVNLLNDLYSNFDTIIEEHG-----VYKVESIGDGYLCVSGL
 ||.|.| || .|||. ||..||.|. .|.|. .| ||.||.|.| || |...|.|.||||.|||.|..||.||..||     .|||| |||.| .|||.
MEKQKNDRLLCQMLPRHVANQLKQGRHPVWPPCYDCVTILFTDIVGFTNLCSWCTPMQVVNMLNDHYTRFDRIIDRHGCYHNYCYKVETIGDAYMVVSGC

PTKNG-------------------YAHIKQIVDMSLKFMDYCKSFKVPHL----PREKVELRIGINSGPCVAGVVGLSMPRYCLFGDTVNTASRMESNGK
|| |.                   ..|...|.|..|. .. .|.|.|.|     | ... .||||..||.|.||||. |||||.||||||.||||||.|.
PTRNEHNQCQCLHHWWTWCFWCFHWQHAQWIADWALDMVECMKTFHVQHHMGELPWNPLRMRIGIHTGPVVCGVVGIRMPRYCYFGDTVNMASRMESTGD

PSMIHMSEAAHSLL-----TDHYPHQYETSS
|  ||.||.....|       . ..|.|.. 
PGQIHVSEETYWCLCLDQFERRRCGQFEFEP
Guanylate_cyc gcy-5.AA Guanylate_cyc 879-1067 43 5.9e-101 346.5 Pfam 1-214 (214) Show / Hide 
Range on Protein: 879-1067
Range on HMM: 1-214/214
Sequence Identity: 43% (94 aa)

VEPEGFDTVTVLFSDVVKFTQLAAKCS----PFQVVNLLNDLYSNFDTIIEEH--GVYKVESIGDGYLCVSGLPTK-----NGYAHIKQIVDMSLKFMDY
|... .| ||..|.|.| ||.....||    |.|.|..|||.|..||.....|  |.|||. ||| |.|||||| .     ....|. ...||.|..|.|
VYAQRYDCVTIMFADIVGFTAFCSRCSMNNMPMQCVRMLNDHYTCFDRLCDQHKFGCYKVKTIGDCYMCVSGLPPPCVQWCCCWHHAWCMADMALDMMEY

CKSFKVPHLPREK-----VELRIGINSGPCVAGVVG--LSMPRYCLFGDTVNTASRMESNGKPS--MIHMSEAAHSLLTDHYPHQYET--SSRGEVIIKG
|... |.|..||      ...||||..||.||||.|  ..|||||..|||||.||||||.|.|.   ||.||.....|..|.. |.|.  ..|||. .||
CQQVNVHHFNREPPTWNCIQMRIGIHTGPVVAGVIGSFQRMPRYCVWGDTVNVASRMESTGVPGSCKIHVSEETYRCLKCHENFQFECHLQHRGEIPVKG

KGV---METFWVLG
||    |||... |
KGKMGEMETYFLHG
HNOBA gcy-5.AA HNOBA 843-873 54 5.7e-07 26.77 Pfam 204-234 (234) Show / Hide 
Range on Protein: 843-873
Range on HMM: 204-234/234
Sequence Identity: 54% (17 aa)

IEERTKELTLEKKKADILLSRMLPKQVAERL
.|. ..||  |||| | ||  |.||.||.||
LEQMHRELEEEKKKTDDLLYSMFPKSVANRL