Gene M01B12.5 (Nematode worm)

M01B12.5

Species: Nematode worm
Alias: M01B12.5, CE31362, aSWK439
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: I:-5.43, WormBase Physical Map location: I: 3096267-3085453,

Classification

Group: Atypical
Family: RIO
Subfamily: RIO1

Sequence

Name Sequence Type Origin Length Description Download
M01B12.5.AA Protein Genbank 548 None Fasta, JSON

Protein domain

Protein domains of M01B12.5.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
RIO M01B12.5.AA RIO 113-390 44 3.2e-148 499.62 SMART 1-253 (253) Show / Hide 
Range on Protein: 113-390
Range on HMM: 1-253/253
Sequence Identity: 44% (131 aa)

DRADRATVEQVLDPRTRLVLFRLLQRGTLLNID--GCISTGKEANVYHATG-----TDNDLAIKIYKTSILTFKDRERYVTGEFRYRHGYCKSNPRKMVA
|..|.||.|.|.|||||..|.....||.. .|.  ||||||||||||||.|     ..|. |.|||.||...||...||..|.||..|||...|.|||| 
DKEDYATYEEVFDPRTRMTLYKMVNRGYIEEINNHGCISTGKEANVYHAMGGDFDKNGNECAVKIYRTSTTEFKRMWRYIQGDFRFKHGYHHINWRKMVR

VWAEKEMRNLARMHEVGLPVPKPHLLKGHVLVMDFLGKDGWPAPLLKNANLSQEVAISKFYQFFVFFFDEKNKNLQNFYLKKKNVILSKTSKKPKKDAEP
.|||||.|||.||.|.|.|.|||.....|||||.|.|.|||||| ||.... .. ...|.                                       .
LWAEKEFRNLQRMYEAGVPCPKPIAWRRHVLVMEFIGDDGWPAPRLKDVEWEEWEMDFKW---------------------------------------E

MYVGLVRDMRRLYRECKLVHADLSEFNMLVH------DGKLWIIDVSQSVEQDHPHALEFLRMDCNNVNKFFRELGVPVLS-VRRLFEVIVD
.|  ....||..|.||.||||||||.|||.|      |.|.||||.|||||.|||..||||..|..|...||| .||.... .|..|| |..
YYWQIMEYMRKMYHECHLVHADLSEYNMLYHDLEDENDCKVWIIDWSQSVECDHPMWLEFLERDIWNIINFFRRKGVDCDDIYREIFERITG
Kinase M01B12.5.AA RIO1 122-266 57 1.3e-86 294.09 In-house 1-148 (225) Show / Hide 
Range on Protein: 122-266
Range on HMM: 1-148/225
Sequence Identity: 57% (85 aa)

QVLDPRTRLVLFRLLQRGTLLNIDGCISTGKEANVYHATGTDND---LAIKIYKTSILTFKDRERYVTGEFRYRHGYCKSNPRKMVAVWAEKEMRNLARM
||.|||||..||..| || .  |.||||||||.|||||  |.      |||||||||| |||||.|| ||||.|||.||.|||||. .||||||||| |.
QVIDPRTRMILFKMLTRGIITEINGCISTGKETNVYHASETNGKRAEYAIKIYKTSILVFKDREKYVDGEFRFRHGHCKHNPRKMIKIWAEKEMRNLKRI

HEVGLPVPKPHLLKGHVLVMDFLGKDGWPAPLLKNANLSQEVAISKFY
     | |.|  .| .||.|.|.|||| .||.||.. ..   .... |
YQSEIPCPEPIMVKSNVLMMEFIGKDGMAAPRLKDYQYKERDQYFHYY
Kinase M01B12.5.AA RIO 120-266 37 1.3e-72 247.57 In-house 1-159 (276) Show / Hide 
Range on Protein: 120-266
Range on HMM: 1-159/276
Sequence Identity: 37% (59 aa)

VEQVLDPRTRLVLFRLLQRGTLLNIDGCISTGKEANVYHATGTDND------------LAIKIYKTSILTFKDRERYVTGEFRYRHGYCKSNPRKMVAVW
.||..||.||....... || .  . .||..|||...||. ... .             ||||..|... ||||..|. |||. .|..||.|.|.|.  |
YEQTNDPYTRMIMYKMVNRGMVESVGNCIGVGKESDIYHCSNENGEDEKEDSKVIPTECAIKIHRTGRTSFKDRKKYRDGEFYFKHRHCKHNWRYMHRLW

AEKEMRNLARMHEVGLPVPKPHLLKGHVLVMDFLGKDGWPAPLLKNANLSQEVAISKFY
|||||||..|... | |.|.| ..| ||||| |...|. |||........   .... |
AEKEMRNMKRLYQSGFPCPEPIDYKRHVLVMEFINHDQMPAPKYPMCQIHEHENMKHVY
Kinase M01B12.5.AA RIO1 155-259 52 4.8e-65 203.32 Pfam 1-113 (200) Show / Hide 
Range on Protein: 155-259
Range on HMM: 1-113/200
Sequence Identity: 52% (59 aa)

NVYHATG-TDND--LAIKIYKTSILTFKDRERYVTGEFRYRHGYCKSNPRKMVAVWAEKEMRNLARMHEVGLPVPKPHLLKGHVLVMDFLG-KDGWPAPL
|||||.. .|..  .|.|||.|....||...||. ..||.||.|...|.|.|| .|||||.||| ||.| |.|.|||.... |||||.|.| ||||||| 
NVYHAYSMEDGKDECAVKIYRTGTTCFKKMKRYRDYDFRFRHRYHHHNWRYMVRMWAEKEFRNLKRMYEAGVPCPKPIDWNRHVLVMEFIGDKDGWPAPR

LKNAN----LSQE
||...    ||.|
LKDVEMELELSEE
Kinase M01B12.5.AA RIO1 299-384 54 7.5e-54 168.41 Pfam 111-200 (200) Show / Hide 
Range on Protein: 299-384
Range on HMM: 111-200/200
Sequence Identity: 54% (49 aa)

PKKDAEPMYVGLVR-DMRRLYRECKLVHADLSEFNMLVHDG-KLWIIDVSQSVEQDHPHALEFLRMDCNNVNKFFRELGVP--VLSVRRL
.. .|| .|  ..|  |||.| ||.|||.||||.|.||||. |.||||..|.|| |||||||||..||.|...|||  ||.  |...| .
SEEEAEEIYDEIIREYMRRMYQECGLVHGDLSEYNILVHDDGKPWIIDWPQAVEHDHPHALEFLERDCRNIINFFRRKGVDERVMDFREI
Kinase M01B12.5.AA RIO1 306-384 59 5.7e-49 167.26 In-house 147-225 (225) Show / Hide 
Range on Protein: 306-384
Range on HMM: 147-225/225
Sequence Identity: 59% (47 aa)

MYVGLVRDMRRLYRECKLVHADLSEFNMLVHDGKLWIIDVSQSVEQDHPHALEFLRMDCNNVNKFFRELGVPVLSVRRL
.|  ....|||.|  | ||||||||.|||.|..|| .|||||||| ||||.|||||||| ||| .|.  .| ...|| .
YYHQMIQYMRRMYQDCRLVHADLSEYNMLYHNDKLYMIDVSQSVEHDHPHSLEFLRMDCKNVNMYFMKHNVIIFPVRDI
Kinase M01B12.5.AA RIO3 117-267 43 2.3e-43 143.75 In-house 1-163 (254) Show / Hide 
Range on Protein: 117-267
Range on HMM: 1-163/254
Sequence Identity: 43% (71 aa)

RATVEQVLDPRTRLVLFRLLQRGTLLNIDGCISTGKEANVYHAT-GTDND-----------LAIKIYKTSILTFKDRERYVTGEFRYRHGYCKSNPRKMV
 .| |. .||.|||....... | |  | |||.||||. |.||  |. .|            |||..||..  ||.|..|.  .||..  . | ||||. 
HSTAEKAVDPKTRLLMYKMVNSGMLETITGCIATGKESVVFHAYGGSMEDEKEDSKVIPTICAIKVFKTTLNEFKNRDKYIKDDFRFKDRFSKLNPRKIH

AVWAEKEMRNLARMHEVGLPVPKPHLLKGHVLVMDFLGKDGWPAPLLKNANLSQEVAISKFYQ
 .|||||| |||||   |.|.|   ||| |.||| |.|.|  ||| ||.  |  |     .||
RMWAEKEMHNLARMQRAGIPCPTVVLLKKHILVMSFIGHDQVPAPKLKEVKLNSEEMKEAYYQ
Kinase M01B12.5.AA RIO 307-387 44 4.6e-41 138.53 In-house 159-247 (276) Show / Hide 
Range on Protein: 307-387
Range on HMM: 159-247/276
Sequence Identity: 44% (40 aa)

YVGLVRDMRRLYRECKLVHADLSEFNMLVHDGKL-------WIIDVSQSVEQDHPHALEFLRMDCNNVNKFFRELGV-PVLSVRRLFEV
|  ....||||| .| |||.|..||||..||||.       ..||..|.|| ||||||...|.|| .|| ||   .|  ....| .|..
YHQCMCYMRRLYQHCRLVHCDFNEFNMMWHDGKHDENDCGFYMIDFPQMVEHDHPHALWYFRRDCKCVNMFFMKRFVYEPFPEREMFDF
Kinase M01B12.5.AA RIO3 314-400 57 7.2e-30 97.41 In-house 168-254 (254) Show / Hide 
Range on Protein: 314-400
Range on HMM: 168-254/254
Sequence Identity: 57% (51 aa)

MRRLYRECKLVHADLSEFNMLVHDGKLWIIDVSQSVEQDHPHALEFLRMDCNNVNKFFRELGV-PVLSVRRLFEVIVDPLMSSKEMET
||.|| || ||||||||.||| | ||.|.||||||||  ||| ||||  || || .||.  ||   || | ||. .   |  . . |.
MRQLYHECTLVHADLSEYNMLWHAGKVWLIDVSQSVEPTHPHGLEFLFRDCRNVSQFFQKGGVKEALSERELFNAVSG-LNITADNEA
Kinase M01B12.5.AA Ciliate-C1 142-180 28 0.000393 6.01 In-house 1-46 (328) Show / Hide 
Range on Protein: 142-180
Range on HMM: 1-46/328
Sequence Identity: 28% (13 aa)

LNIDGCISTGKEANVYHATGTDND--LAIKIYKT-----SILTFKD
. |   | .|. . |  .   .|.  .|.|. |        |||||
MKIMKTIGHGYTCKVFYCKMPNNQKVYAVKQFKNEYTSQQQLTFKD