Gene mek-1 (Nematode worm)
mek-1
Sequence
Protein domains of mek-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | mek-1.AA | MEK7 | 72-325 | 65 | 1.7e-208 | 698.96 | In-house | 1-269 (269) | Show / Hide |
Range on Protein: 72-325 Range on HMM: 1-269/269 Sequence Identity: 65% (177 aa) LQFVEDIGHGSCGTVTKCRYKS--VIMAVKTMPRTSNSYEMSRILMDLDVICLSFDCPYIVRCFGYFITNFDVRVCMECMATCLDRLLIRIKQP----IP |....|.||||||.|.|.|.|| ||||||.|.||.|..|..||||||||.|...||||||.|||||.|..||..|||||.||.|.||.|||.| || LHHIGDMGHGSCGHVWKMRHKSSGVIMAVKQMRRTGNKEENKRILMDLDVMCMCHDCPYIVQCFGYFMTDSDVWICMECMSTCCDKLLKRIKHPKLDFIP ERIIGKLSVSIIKALHYLKTKHQIMHRDVKPSNILLDWSGVIKLCDFGIAGRLIESRAHSKQAGCPLYMGPERLDP--NNFDSYDIRSDVWSFGVTLVEL |.||||..|.||.||||||.||.|||||||||||||||.|.||||||||.||...|.||...||||.||.|||.|| .|...||||.||||.|.||||| EQIIGKMVVAIINALHYLKEKHGIMHRDVKPSNILLDWRGNIKLCDFGISGRMVDSKAHTRSAGCPAYMAPERIDPPDPNNPKYDIRADVWSLGITLVEL ATGQYPYAG--TEFDMMSKILND--EPPRLDPAK---FSPDFCQLVESCLQRDPTMRPNYDMLLQHPFV |||||||.| .||.||.||||| |||.|.... |||||||.|..|||.|..|||.|.||.||||. ATGQYPYPGCDMEFEMMTKILNDNLEPPCLPEHMKYNFSPDFCQFVDKCLQKDHRMRPKYRMLMQHPFI |
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| Kinase | mek-1.AA | STE7 | 72-325 | 45 | 2.5e-156 | 525.64 | In-house | 1-288 (288) | Show / Hide |
Range on Protein: 72-325
Range on HMM: 1-288/288
Sequence Identity: 45% (132 aa)
LQFVEDIGHGSCGTVTKCRYKS--VIMAVKTMPRTSNS-YEMSRILMDLDVICLSFDCPYIVRCFGYFITNFD--VRVCMECMA-TCLDRLLIRIKQ---
|......|||..|.|.|.|.| .|||||....| |. |. .|||.|||.. . ||||||...|.|.|. | . |||.|. .||| .. |.|.
LEHIGELGHGNYGVVYKMRHKPSGKIMAVKRIRLTNNDPEEQKQILMELDVLHKCNDCPYIVQFYGAFYTEGDDCIWICMEYMDGGCLDKFYKRVKKVYR
-----PIPERIIGKLSVSIIKALHYLKTKHQIMHRDVKPSNILLDWSGVIKLCDFGIAGRLIESR-AHSKQAGCPLYMGPERLDPNNFDSYDIRSDVWSF
.|||.|.|| .|..||.||||..||.|.||||||||||....| .|||||||.|.|..| |.....||. || |||.|. |...||.||||||.
GIKKGRIPEQILGKIAVAVIKGLHYLHEKHKIIHRDVKPSNILVNSRGQVKLCDFGICGQLVDSMDAATTFVGCQPYMAPERIDG-NKQHYDVRSDVWSL
GVTL-VELATGQYPYA--GT-----------------EFDMMSKILND-EPPRLDPAKFSPDFCQLVESCLQRDPTMRPNYDMLLQ-HPFV
|.|. .|.|||.|||. | .|.....|.|. .||||. ||||.|...|. |||.||..||.|..|.. |||.
GITMGIEMATGRYPYPNWNTHPPDQKQYNNMFQPEMAIFEQLTCIVNENPPPRLP--KFSPEFQDFVNKCLQKDPNERPKYHQLMKEHPFI
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| Kinase | mek-1.AA | MEK4 | 72-325 | 42 | 2.4e-101 | 331.58 | In-house | 1-275 (275) | Show / Hide |
Range on Protein: 72-325 Range on HMM: 1-275/275 Sequence Identity: 42% (118 aa) LQFVEDIGHGSCGTVTKCRYKS--VIMAVKTMP-RTSN-----SYEMSRILMDLDVICLSFDCPYIVRCFGYFITNFDVRVCMECMATCLDRLLIRI--- || . || |. ||| | ..| .||||| . |. | ||..||. | .|||||. .| | .||| | . .| . .. LQDLGEIGNGAFGTVNKMWHKESGKIMAVKRIRCNNVDPDDAFHKEQKRLLMEHDVVMKSENCPYIVKFYGACFKEGDCWICMELMDISMDKFYKYVYMV -KQPIPERIIGKLSVSIIKALHYLKTKHQIMHRDVKPSNILLDWSGVIKLCDFGIAGRLIESRAHSKQAGCPLYMGPERLDP-NNFDSYDIRSDVWSFGV |. ||| |.|. | ...|| |||..|.| |||||||||||| .| .||||||| | | .| | .. ||| || |||.|| | | ||||||||| |. QKSRIPENIMGHITVCTVDALNYLKETHKIIHRDVKPSNILLDRHGCVKLCDFGICGQLVDSIAKTHDAGCRPYMAPERIDPEQNMDGYDIRSDVWSLGI TLVELATGQYPYAGTE----FDMMSKILNDEPPRLDPAKF----SPDFCQLVESCLQRDPTMRPNYDMLLQHPFV |..|.|||..|| . . || .. . . .||.|.. .. |...|. . || | || || |...||. TMYEVATGKFPYRKWNDASVFDQICMVVKGDPPILHHDHHDMHYSMPMCRFINTCLTKDRNHRPKYDNLKKFPFY |
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| Kinase | mek-1.AA | STE | 72-325 | 26 | 6.5e-96 | 324.95 | In-house | 1-359 (359) | Show / Hide |
Range on Protein: 72-325 Range on HMM: 1-359/359 Sequence Identity: 26% (98 aa) LQFVEDIGHGSCGTVTKCRYK-----------------SVIMAVKTMP----------------RTSNSYEMSRILMDLDVICLSFD-CPYIVRCFGYFI ....| ||.|..||| |.... .|||.| |. ...|. || .||..... . . .|.||...|... WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF TN-------FDVRVCMECMA-TCLDRLLIRIK-------------QPIPERIIGKLSVSIIKA-LHYLKTKHQIMHRDVKPSNILLDWSGVIKLCDFGIA . .. .||| |. .|| .. . . ...|| .|.. ..|.|. |.|| .| |.|||.||.|||| .||||||.. KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH-IIHRDIKPANILL-----VKLCDFGVC GRLIESRA----------------HS-KQAGCPLYMGPERLDPNN---FDSYDIRSDVWSFGVTLVELATGQYPY---AGTE--------------FDMM |.|..| | .. .|.| .| ||....|. . ||...|.||.| |..|.|||..|. .. |... GQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL SKILNDEPPRLD------------------PAKFSPDFCQLVESCLQRDPTMRPNYDMLLQ--HPFV .|.|..||.| | |.||.|.. .. |||.|| ||... ||. |||. -CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI |
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| Kinase | mek-1.AA | MEK3 | 72-325 | 42 | 6.9e-96 | 324.87 | In-house | 1-264 (264) | Show / Hide |
Range on Protein: 72-325 Range on HMM: 1-264/264 Sequence Identity: 42% (113 aa) LQFVEDIGHGSCGTVTKCRYK--SVIMAVKTMPRTSNSYEMSRILMDLDVICLSFDCPYIVRCFGYFITNFDVRVCMECMATCLDRL---LIR-IKQPIP . ... | | | | | | . ||||| .. | || | |.|||.|. | |||| |. .| || .||| | |||| . . ... || MVVICELGRGAYGIVDKMRHRQSGTIMAVKRIRMTVNSQEQKRMLMDMDICMRSSDCPYTVHFYGAMFREGDVWICMEVMDTCLDKFYRHVYKPHGMHIP ERIIGKLSVSIIKALHYLKTKHQIMHRDVKPSNILLDWSGVIKLCDFGIAGRLIESRAHSKQAGCPLYMGPERLDPNNFD-SYDIRSDVWSFGVTLVELA | |.||...||..||||.... .. ||||||||.|. | .|.||||| | |..| | .||| || ||| || ||..|||||.|.|..|.| EDILGKIAMSIVSALHYMHEQLKVIHRDVKPSNVLINHHGQVKMCDFGISGYLVDSMAKTIDAGCKPYMAPERIDPEMNQKGYDVKSDVWSLGITMIEMA TGQYPYA--GTEFDMMSKILNDEPPRLDPAK-FSPDFCQLVESCLQRDPTMRPNYDMLLQHPFV .| |||. .| |. . . ||.| | ||||. .. ||. ... ||.| |..|||. IGRYPYDNWHTPFQQLKQVVEEPPPQLPMEKGFSPDCQDFINQCLKKNYMERPSYPELMEHPFM |
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| Kinase | mek-1.AA | STE7-Unclassified | 72-325 | 31 | 1.6e-76 | 260.49 | In-house | 1-301 (301) | Show / Hide |
Range on Protein: 72-325 Range on HMM: 1-301/301 Sequence Identity: 31% (96 aa) LQFVEDIGHGSCGTVTKCRYKS--------VIMAVKTMP-RTSNSYEMSRILMDLDVICLSFD-CPYIVRCFGYFITNFD---VRVCMECMA-------- |.... .|||. ||| ||. | .||| |. | ... | ||. | .. .. .||||...|.... . ||| |. LERLKYLGHGMHGTVVKCLHKNGMVIARDGKIMAWKVIPTMDNDNEFMKQILRELKTLH-KCQPHPYIVHYYGAYYHECMDCKIHICMEYMDCGSLDNKI TCLDRLL----IRIKQPIPERIIGKLSVSIIKALHYLKTKHQIMHRDVKPSNILLDWSGVIKLCDFGIAGRLIESR--AHSKQAGCPLYMGPERLDPN-- . ..... | .. .|||...||. ..|..|.||. ||.| |||.||.|||.. | .|.||||..|.|. . | . .|| || |||. . DIYKKMYERGPI-RGGWIPEPVLGKIAYQVIHGLWYLHEKHHIIHRDIKPGNILVNSKGQVKICDFGVCGQLENTLDEAKT-WVGCQMYMSPERIQGQMP NFDSYDIRSDVWSFGVTLVELATGQYPY---------AGT-------EFDMMSKILNDEPPRLDPAK----FSPDFCQLVESCLQRDPTMRPNYDMLLQ- . || ..||.||.| |. |.||| ||| . . ... |.|.| . |||. . .|..| .... |.. .|. || . || HRPSYSVKSDIWSLGLTIWECATGKYPYEYNFQSEQYNQNFQPENMSFWELLSCIVNFPVPRLPDDPEDIIWSKEFMDFISKCCKKHPRERPDIHQLLNE HPFV ||.. HPWI |
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| Kinase | mek-1.AA | S_TKc | 72-325 | 28 | 2.4e-66 | 227.66 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 72-325 Range on HMM: 1-231/231 Sequence Identity: 28% (77 aa) LQFVEDIGHGSCGTVTKCRYKS--VIMAVKTMPRTSNSYEMSRILMDLDVICLSFDCPYIVRCFGYFITNFDVRVCMECMAT---CLDRLLIRIKQP--- .... ||.|. |.| ||| |. |.|.| .. .|. ... ..|.||.....| . .. ..||.. . | ... . . . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR --IPERIIGKLSVSIIKALHYLKTKHQIMHRDVKPSNILLDWSGVIKLCDFGIAGRLIESRAHSKQAGCPLYMGPERLDPNNFDSYDI-RSDVWSFGVTL .|| . .. |..|| |. . .|.|||.||.||||| .||.||||.| .| . . | | || || | .|. ..|.||.|..| FPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL------GYGKCKCDWWSCGCIL VELATGQYPYAGTEFDMMSKILNDEPPRLDPAKFSPDFCQLVESCLQRDPTMRPNYDMLLQ-------HPFV |...|. |. ... |. ||. ||....... |||.||. || .|| ||.. YEMLCGYPPFP-QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | mek-1.AA | MEK1 | 72-269 | 43 | 2.3e-54 | 184.02 | In-house | 1-195 (297) | Show / Hide |
Range on Protein: 72-269 Range on HMM: 1-195/297 Sequence Identity: 43% (87 aa) LQFVEDIGHGSCGTVTKCRYKS--VIMAVKTMPRTSNSYEMSRILMDLDVICLSFDCPYIVRCFGYFITNFDVRVCMECM-ATCLDRLLIRIKQPIPERI .. ....||| | |.||| . .||| | . |. .| |. |||| .| |. . .. .||| | || .| .. . |||.| FEKIGELGHGNGGVVMKCRHRHTGMIMARKLIHLEIKPAIRNQIIRELQVLH-ECNSPYIVGFYGAFYSDGEISICMEYMDGGSLDQVLKKA-GRIPEKI IGKLSVSIIKALHYLKTKHQIMHRDVKPSNILLDWSGVIKLCDFGIAGRLIESRAHSKQAGCPLYMGPERLDPNNFDSYDIRSDVWSFGVTLVELATGQY .||.|| ... | ||. ||.|||||||||||| .| |||||||..|.||.| | | | || |||| | ..||.||.|. |||.| |.| LGKVSVAVLRGLTYLRDKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANS-FVGTRSYMSPERLQGTH---YTVQSDIWSMGLSLVEMAIGRY P | P |
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| Kinase | mek-1.AA | MEK5 | 72-325 | 36 | 1.2e-52 | 181.24 | In-house | 1-254 (254) | Show / Hide |
Range on Protein: 72-325 Range on HMM: 1-254/254 Sequence Identity: 36% (97 aa) LQFVEDIGHGSCGTVTKCRY--KSVIMAVKTMPRTSNSYEMSRILMDLDVICLSFDCPYIVRCFGYFITNFDVRVCMECMATCLDRLLIRIKQPIPERII ... . .||| ||| | . |.||| . . |. . .| | | |||. .| | . . .| | | | . . ||| |. IRYRDTLGHGNGGTVYKAYHVPSGKILAVKVI-LLDITLELQKQIMSELEILYKCDSPYIIGFYGAFFVENRISICTEFM----DGGSLDMYRCIPEHIL GKLSVSIIKALHYLKTKHQIMHRDVKPSNILLDWSGVIKLCDFGIAGRLIESRAHSKQAGCPLYMGPERLDPNNFDSYDIRSDVWSFGVTLVELATGQYP |...|.|.| | || .||||||||||.| | |||||||.. |..| .. | || |||. | | | ||||| |. ..|.|||..| GRMTVAIVKGLNYLW-NLKIMHRDVKPSNMLVNTQGQIKLCDFGVSTQLVNSITRT-YIGTNAYMAPERI---SGDQYGIHSDVWSLGIFFMEMATGRFP YAGTEFDM--------MSKILNDEPPRLDPAKFSPDFCQLVESCLQRDPTMRPNYDMLLQHPFV | .. | . | ...|||| ||| | . .. |.|. | || . |.||||. YPQIQRDQGELMPIQLLQCIVDEHPPRLPVDKFSEPFVHFINQCMQKQPKDRPKPQDLMQHPFI |
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| Kinase | mek-1.AA | Pkinase | 72-325 | 24 | 1e-49 | 176.28 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 72-325 Range on HMM: 1-293/293 Sequence Identity: 24% (73 aa) LQFVEDIGHGSCGTVTKCRYKSV--IMAVKTMPRTSNSYEMSRIL---MDLDVICLSFDCPYIVRCFGYFITNFDVRVCMECMAT-----CLDRLLI-RI ..... || || |.| ||. |. | |||.... ... .. ... . . . ..|.|||....| .. .. ..||.. | ... . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR KQPI--PERIIGKLSVSIIKALHYLKTKHQIMHRDVKPSNILLDWSGVI----KLCDFGIAGR--LIESRAHSKQAGCPLYMGPERLDPNNFDSYDIRSD . .. .|. . . |...| |. . |.|||.||.|||.| |.| |.||||.| . .. . .| | || || . |. ..| HGCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR--GGQYYGPKVD VWSFGVTLVELATGQYPYAGT-------EFDMMSKILNDEPPRLDPAKFS-------------------PDFCQLVESCLQRDPTMRPNYDMLLQHPFV .||.|..| |...|. |. | . |. .|. .... | . | .........||..||. ||. . .||||.. MWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | mek-1.AA | STE20 | 72-325 | 28 | 2.1e-48 | 167.13 | In-house | 1-288 (288) | Show / Hide |
Range on Protein: 72-325
Range on HMM: 1-288/288
Sequence Identity: 28% (83 aa)
LQFVEDIGHGSCGTVTKCRYK--SVI----MAVKTMPRTSNS---YEMSRILMDLDVICLSFDCPYIVRCFGYFITN----FDVRVCMECMAT-CLDRLL
...| ||.|| |.| |.. | . |.| |. . . |. |. .. . .|.||. .| .. . . ..|| .. .| ..
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCK-HPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIM
I---RIKQ-----PIPERIIGKLSVSIIKALHYLKTKHQIMHRDVKPSNILLDWSGVIKLCDFGIAGRLIE----SRA--HSKQAGCPLYMGPERLDPNN
.... |. | | . ..|.|| ...|.|||.| ||||. .| .||.||| .. |.. ... | | .| || . .
KHCMKCGKNHKGHPMNEEQIAYICREVLQGLDYL-HSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCME
F--DSYDIRSDVWSFGVTLVELATGQYPYAG-TEFDMMSKIL--NDEPPRLD---PAKFSPDFCQLVESCLQRDPTMRPNYDMLLQHPFV
. || ..|.||.| |. |.|.|. ||. . .| .|. . .||.| | |.||.|...|..|||.|| || . ||.|||.
GPDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
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| Kinase | mek-1.AA | TKL | 78-323 | 18 | 6e-41 | 142.35 | In-house | 1-364 (364) | Show / Hide |
Range on Protein: 78-323
Range on HMM: 1-364/364
Sequence Identity: 18% (68 aa)
IGHGSCGTVTKCRYKS----------VIMAVKTMPRTSNSYEMS-------------------------RILMDLDVICLSFDCPYIVRCFGYFITNFD-
|| |. |.| | ... .|||........ ... . ........| ||.. || . . .
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG
------------VRVCMECM-ATC-LDRLLIRIKQPIPERIIGKLSVSIIKALHYLKT-------KHQIMHRDVKPSNILLD--WSGV------------
|| . . |..|. . ... .| ....|| . | .| ||| |..|||.| | |
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC
IKLCDFGIAGRLIESR--------------------AHSKQAGCPLYMGPERLDPNNFDS-------------YDIRSDVWSFGVTLVELATGQYPYA-G
.|.||||.. .. .| ....| | | .| || |. ..... |. ..||.|||. | |..|.. ||.
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDY
T----------EFDMMSKILNDEPPRLD-----------PAKFSPDFCQLVESCLQRDPTMRPNYDMLLQHP
| ..| ... ..| .. . . |....| . | . ||. ||. . .|..
PYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
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| Kinase | mek-1.AA | TyrKc | 72-331 | 22 | 9.6e-15 | 15.72 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 72-331 Range on HMM: 1-280/280 Sequence Identity: 22% (66 aa) LQFVEDIGHGSCGTVTKCRYKSVIMAVKTMPRTSNSYEMSRILMDLDVICLSF--DCPYIVRCFGYFITN-------FDVRVCMECMAT-CLDRLLIRIK ... . .|.| |.| |...| . |||.. . . .. . . | .. . | |||..|. .. . . || |. .|. | . . ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA----REDFMREARIMC-KLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR QPIPERIIGKLSVSIIKALHYLKTKHQIMHRDVKPSNILLDWSGVIKLCDFGIAGRLIESR--------AHSKQA--GCP--L---YMGPERLDPNNFDS .. . . .. | . || | .. ||| |.|.. ...| .||| . | |.. .|. |. | | || . |. PKLCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGLS-RDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI---NYGK YDIRSDVWSFGVTLVELAT-GQYPYAG------TEFDMMSKILNDEPPRLDPAK--------FSPDFCQLVESCLQRDPTMRPNYDMLLQHPFVVHHEKI . . ||||||||.. |. | || || | . .... .. . . .. |. ... |. ..| ..|| .||. . ||.. FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQ-PPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--------HECF |
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| Kinase | mek-1.AA | MEK1 | 275-325 | 35 | 2.8e-11 | 34.29 | In-house | 247-297 (297) | Show / Hide |
Range on Protein: 275-325 Range on HMM: 247-297/297 Sequence Identity: 35% (18 aa) FDMMSKILNDEPPRLDPAKFSPDFCQLVESCLQRDPTMRPNYDMLLQHPFV |.|. | |. ||.|. || .| . |. ||.. | | . .|..|.|. FEMLDYIVNEPPPKLPHRVFSEEFQDFVDKCLIKNPDERADLKQLMVHTFI |
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| Kinase | mek-1.AA | Pkinase_Tyr | 243-272 | 46 | 4e-06 | 21.52 | Pfam | 187-218 (270) | Show / Hide |
Range on Protein: 243-272 Range on HMM: 187-218/270 Sequence Identity: 46% (15 aa) NFDSYDIRSDVWSFGVTLVELAT-GQYP-YAG |. . . ||||||||.. |. | |. | |.| NYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPG |
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| Kinase | mek-1.AA | Pkinase_Tyr | 72-107 | 23 | 0.013102 | 9.46 | Pfam | 1-42 (270) | Show / Hide |
Range on Protein: 72-107 Range on HMM: 1-42/270 Sequence Identity: 23% (10 aa) LQFVEDIGHGSCGTVTKCRYK------SVIMAVKTMPRTSNS ..| . .|.|. |.| |...| . |||... .. . ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMH |
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| Kinase | mek-1.AA | Pkinase_Tyr | 198-215 | 50 | 0.27927 | 4.96 | Pfam | 141-158 (270) | Show / Hide |
Range on Protein: 198-215 Range on HMM: 141-158/270 Sequence Identity: 50% (9 aa) NILLDWSGVIKLCDFGIA |.|.. ..|.| |||| | NCLVTENNVVKICDFGLA |
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