Gene pmk-1 (Nematode worm)

pmk-1

Species: Nematode worm
Alias: CE06686, B0218.3, aSWK200, pmk-1
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: IV: 8148779-8150728, WormBase Genetic Map location: n/a,

Classification

Group: CMGC
Family: MAPK
Subfamily: p38

Sequence

Name Sequence Type Origin Length Description Download
pmk-1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 285 Kinase domain by global Sugen HMM Fasta, JSON
pmk-1.AA Protein Genbank 377 None Fasta, JSON

Protein domain

Protein domains of pmk-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase pmk-1.AA p38 35-319 75 1.3e-232 779.1 In-house 1-289 (289) Show / Hide 
Range on Protein: 35-319
Range on HMM: 1-289/289
Sequence Identity: 75% (218 aa)

YINLTPIGTGAYGTVCAAECTRSGTR---VAIKKFNRPFQSIIHARRTYRELRLLRCMCHENIIDLLDVFTP-NENVNDIEDVYFVSMLMGADLSNILKI
| ||.|.|.||||.||.||..|.|..   |||||..|||||.|||.|||||||||..|.|||.|.||||||| ....||..|||.|...|||||.||.|.
YQNLQPVGSGAYGQVCKAEDRRTGQKRRYVAIKKLMRPFQSEIHAKRTYRELRLLKHMRHENVICLLDVFTPPAHSMNDFQDVYMVTHFMGADLNNIMKC

QRLNDDHIQFLVYQILRGLKYIHSADIIHRDLKPSNIAVNEDCELKILDFGLARQTDSEMTGYVATRWYRAPEIMLNWMHYTQTVDVWSVGCILAELITG
|||.|||||||||||||||||||||.|||||||||||||||||||.||||||||..|.||||||||||||||||||||||||||||.||||||.||||||
QRLSDDHIQFLVYQILRGLKYIHSAGIIHRDLKPSNIAVNEDCELRILDFGLARHCDDEMTGYVATRWYRAPEIMLNWMHYTQTVDIWSVGCIMAELITG

KTLFPGSDHIDQLTRIMSVTGTPDEEFLKKISSEEARNYIRNLPKMTRRDFKRLFAQATPQAIDLLEKMLHLDPDRRPTAKEAMEHEYL
.|||||.||||||.|||.|.|||||||..||.||||||||...|.|.||||...|..|.|||||||||||.||||.| ||.|||.|.|.
RTLFPGDDHIDQLQRIMKVCGTPDEEFWQKIQSEEARNYIQSYPQMPRRDFHHVFMGANPQAIDLLEKMLELDPDKRITAEEAMQHPYF
Kinase pmk-1.AA MAPK 35-319 55 8.70000000001e-202 676.66 In-house 1-328 (328) Show / Hide 
Range on Protein: 35-319
Range on HMM: 1-328/328
Sequence Identity: 55% (181 aa)

YINLTPIGTGAYGTVCAAECTR------SGTRVAIKKFNRPFQSIIHARRTYRELRLLRCM-CHENIIDLLDVFTPN-----ENVNDIEDVYFVSMLMGA
| .| ||| ||||.||.| ..|      .|..|||||. ||||. .|..|||||..|||.. .||||| |||.|||      ..  . .|.|.|. ||..
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

DLSNILKIQR-LNDDHIQFLVYQILRG--LKYIHSADIIHRDLKPSNIAVNEDCELKILDFGLARQTDSE-----------------MTGYVATRWYRAP
|| .|.| |. |.|||||...||||||  |||||||..||||||||||.|||.|.|||.||||||..|.|                 ||.||||||||||
DLHQIIKSQQPLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAP

EIMLN--WMHYTQTVDVWSVGCILAELIT-GKTLFPGSDHIDQLTRIMSVTGTPDEEFLKKIS-SEEARNYIRNL---PKMTRRDFKRLFAQ----ATPQ
|||||  |||||..||.||||||.||..| .|.||||.|.|||...||.|.|||.|||...|. ||.|||||..|   ||....... .|      |.||
EIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANPQ

AIDLLEKMLHLDPDRRPTAKEAMEHEYL
|||||||||..|||.| |..||..|.|.
AIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase pmk-1.AA ERK 35-319 50 4.1e-155 521.6 In-house 1-307 (307) Show / Hide 
Range on Protein: 35-319
Range on HMM: 1-307/307
Sequence Identity: 50% (156 aa)

YINLTPIGTGAYGTVCAAECTR-----SGTRVAIKKFNRPFQSIIHARRTYRELRLLRCMC-HENIIDLLDVFTPNENVNDIEDVYFVSMLMGADLSNIL
|  . .|| ||||.||.|  .      .|..|||||  ..|   | . ||.||..|||    ||||| |.|.. ||    ...|.|.|. ||  ||  | 
YQIIKQIGHGAYGVVCSAIDKEYCFDETGQKVAIKKIENAFDHPIYCKRTLREIKLLRHFKGHENIICLFDIMMPNSPE-QYNDIYCVEELMETDLHQII

KIQ-RLNDDHIQFLVYQILRGLKYIHSADIIHRDLKPSNIAVNEDCELKILDFGLARQTDS-----------EMTGYVATRWYRAPEIMLNWMHYTQTVD
. | .|.|||.|...||||.||||||||..|||||||||| ||..| ||| ||||||  |.            ||.||||||||||||||.|  ||. .|
NSQQELSDDHCQYFMYQILCGLKYIHSANVIHRDLKPSNILVNSNCDLKICDFGLARCFDASYQENHECNQNFMTEYVATRWYRAPEIMLSWQKYTKAMD

VWSVGCILAELITGKTLFPGSDHIDQLTRIMSVTGTP-DEEFLKKISSEEARNYIRNLPK--MTRRDFKRLFAQAT--PQAIDLLEKMLHLDPDRRPTAK
.||.|||.||.. .|.|||| |...|..|| ...||| .|| |..| ||.|..||.|||.   . .... .|  |   |||||||||||. ||| | |..
IWSCGCIFAEMLGRKPLFPGKDYVHQINRIFQIIGTPHSEEDLQYICSENAWKYIKNLPNPVRPPKPWENIFPNANCNPQAIDLLEKMLVFDPDKRITVE

EAMEHEYL
|. ||.|.
ECLEHPYF
Kinase pmk-1.AA CMGC 35-319 28 1.4e-145 481.88 In-house 1-513 (513) Show / Hide 
Range on Protein: 35-319
Range on HMM: 1-513/513
Sequence Identity: 28% (145 aa)

YINLTPIGTGAYGTVCAAECTRSG--------------TRVAIKKFNRPFQSIIHAR----------RTYRELRLLRCMC-----------------HEN
| .. .|| |.||.|. . ..|..               .|||||. .||   ..|.          |..||...|...                  |.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IIDLLDVFTPNENVND-----------IEDVYFVSMLMGADLSNILKIQR----------LNDDH------------IQFLV------YQILRGLK--YI
|. |.|.|..... ..            ...|.|  .|. || ...| ..          |.. |            |....      ||||||||  |.
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HSAD--IIHRDLKPSNIAVNEDCEL--------------------KILDFGLARQTDSE------------------------MTGYVATRWYRAPEIML
||..  ||||||||.|| .|..|||                    || ||||||.....                        .| ||.|||||||||.|
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

NW---------MHYTQTVDVWSVGCILAELITG--------KTLFP-----------GSDHIDQLTRIMSVTGTP----------------DEEFLKKIS
.|         ||||...|.||||||.||..||        |.|||           |..||||| .|. | |||                .||. ..|.
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

--------------------SEEARNYIRN---LPKMTRRDFKRLFAQ-----------------------------------ATPQAIDLLEKMLHLDP
                    || |||||..   .|.  ....|.||                                     ..|||||||.|||..||
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

DRRPTAKEAMEHEYL
|.|.||..|..|.|.
DKRITAEQALQHPYF
Kinase pmk-1.AA JNK 35-319 42 2.3e-123 416.14 In-house 1-309 (309) Show / Hide 
Range on Protein: 35-319
Range on HMM: 1-309/309
Sequence Identity: 42% (133 aa)

YINLTPIGTGAYGTVCAAECTRSGTRVAIKKFNRP--FQSIIHARRTYRELRLLRCMCHENIIDLLDVFTPNENVNDIEDVYFVSMLMGADLSNILK--I
|.|| .|| || |.||.|  . .. ||||||  ||  ||   |..| |||. .. |  |.||| .. .||| |.. . .||| |  .| . | ..     
YQNLKFIGQGAQGIVCMAFDQVTNQRVAIKKMMRPDNFQNWMHWKRAYREFICMKCINHKNIIKMYNCFTPQETLEEFQDVYIVMEYMDWNLCQVIHSTF

QRLNDDHIQFLVYQILRGLKYIHSADIIHRDLKPSNIAVNEDCELKILDFGLARQTDSE--MTGYVATRWYRAPEIMLNWM-HYTQTVDVWSVGCILAEL
 .|  . . .|.||...| |. ||. ||||||||||| ||.|| |||.|||.||  |    || || ||.|||||. .  |  |.  ||.||||||.||.
MELDHERMSYLFYQMCCGIKHLHSMGIIHRDLKPSNIVVNQDCTLKICDFGHARTEDPTFMMTPYVVTRYYRAPEVICGMMDNYKENVDIWSVGCIMAEM

ITGKTLFPGSDHIDQLTRIMSVTGTPDEEFLKKISSEEARNYIRNL---PKMTRRDFKRLF--------AQATPQ-------AIDLLEKMLHLDPDRRPT
|... ||||.||||| ..|... |||| .|...   . .|||..|.   |. . . |...|        .|..|.       | ||| .||  .||.|  
IRHHVLFPGKDHIDQWNKIIEFLGTPDPHFMMQM-QPHVRNYVENRNMDPYYQPYNFHEHFPDTLFPDVMQSEPKDHLTCHMARDLLFRMLVINPDDRIS

AKEAMEHEYL
  .| .|.|.
VDDALQHPYI
Kinase pmk-1.AA ERK1 35-319 50 9.20000000001e-115 387.57 In-house 1-289 (289) Show / Hide 
Range on Protein: 35-319
Range on HMM: 1-289/289
Sequence Identity: 50% (147 aa)

YINLTPIGTGAYGTVCAAECTRSGTRVAIKKFNRPFQSIIHARRTYRELRLLRCMCHENIIDLLDVFTPNENVNDIEDVYFVSMLMGADLSNILKIQRLN
|.||  || |||| ||.|  |. ..||||||   ||    .  || ||...|    |||||.. |.    . .. . ||| |  ||  ||  .|| |.| 
YTNLQYIGEGAYGMVCSAYDTVHKQRVAIKKIS-PFEHQTYCQRTLREIKILTRFKHENIINIQDIIR-ADTIEQMRDVYIVQCLMETDLYKLLKTQHLS

DDHIQFLVYQILRGLKYIHSADIIHRDLKPSNIAVNEDCELKILDFGLARQTDSE------MTGYVATRWYRAPEIMLNWMHYTQTVDVWSVGCILAELI
 ||| . .||||||||||||| ..||||||||. .|  |.||| |||||| .| |      .| |||||||||||||||   ||. .|.|||||||||..
NDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEML

TGKTLFPGSDHIDQLTRIMSVTGTPDEEFLKKISSEEARNYIRNLPKMTRRDFKRLFAQATPQAIDLLEKMLHLDPDRRPTAKEAMEHEYL
  . .|||   .|||  |..| | | .. |. |  | ||||.. ||  ..  ..||| .| ..|.|||.|||   |..| |  ||. | ||
SNRPIFPGKHYLDQLNHILGVLGSPSQDDLNCIINEKARNYLQSLPHKPKVPWARLFPKADSKALDLLDKMLTFNPHKRITVEEALAHPYL
Kinase pmk-1.AA ERK5 35-319 45 1.4e-112 380.32 In-house 1-295 (295) Show / Hide 
Range on Protein: 35-319
Range on HMM: 1-295/295
Sequence Identity: 45% (134 aa)

YINLTPIGTGAYGTVCAAECTRSGTRVAIKKFNRPFQSIIHARRTYRELRLLRCMCHENIIDLLDVFTPNENVNDIEDVYFVSMLMGADLSNILK-IQRL
|  .  ||.|||| ||.|   . | .|||||    |  .  |.||.|||..||   |.||| . |.  | .   .. ||| |  || .||  |.   | .
YKIIEKIGNGAYGVVCSARRRKNGQQVAIKKIPNAFDVVTNAKRTFRELKILRHFRHDNIIAIRDILMPKVPYSEMKDVYVVFDLMESDLHQIIHSNQPF

NDDHIQFLVYQILRGLKYIHSADIIHRDLKPSNIAVNEDCELKILDFGLARQTDS--------EMTGYVATRWYRAPEIMLNWMHYTQTVDVWSVGCILA
  .|| . .|||||||||.|||..|||||||||. ||| ||||| |||.||             || |||||||||||.|.    ||| .||||||||. 
TLEHIRYFLYQILRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTFSPDKHQMFMTEYVATRWYRAPELMFSSHDYTQAIDVWSVGCIFG

ELITGKTLFPGSDHIDQLTRIMSVTGTPDEEFLKKISSEEARNYIRN-LPKMTRRDFKRLFAQATPQAIDLLEKMLHLDPDRRPTAKEAMEHEYL
|.|. . .|||   |.||  || | |.|    .. .|..  .||.   .|  . .|..... .| .||.||| .||  .|  | |. .|. | .|
EMIARRQMFPGKNYIHQLQLIMMVLGMPPPHMIQAVSADHVYNYFQKNFPNRQPKDWEKVYPKADRQALDLLARMLRFEPSERITVNKALQHPFL
Kinase pmk-1.AA ERK7 35-319 39 1.7e-102 346.85 In-house 1-292 (292) Show / Hide 
Range on Protein: 35-319
Range on HMM: 1-292/292
Sequence Identity: 39% (116 aa)

YINLTPIGTGAYGTVCAAECTRSGTRVAIKKFNRPFQSIIHARRTYRELRLLRCMC-HENIIDLLDVFTPNENVNDIEDVYFVSMLMGADLSNILK-IQR
|  .  .| |||| |  | . |..  ||.||    |.  . | ||.||  .|. .  |.||| |..|.  . .     |.| |   | .|| .. .  . 
YEIRKRLGKGAYGIVWKAYDKRTKQVVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLINVIRADND----RDIYLVFEFMETDLHAVIRKGNI

LNDDHIQFLVYQILRGLKYIHSADIIHRDLKPSNIAVNEDCELKILDFGLARQ-TDSE--------MTGYVATRWYRAPEIMLNWMHYTQTVDVWSVGCI
| | | |. .||.|| .||.||...|||||||||| .. .| .|. ||||||  .. |        .| ||||||||||||.|   .||. || ||.|||
LKDIHKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSECMVKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIGCI

LAELITGKTLFPGSDHIDQLTRIMSVTGTPDEEFLKKISSEEARNYIRNLPKMTRRDFKRLFAQATPQAIDLLEKMLHLDPDRRPTAKEAMEHEYL
|.|...|| .|||.  ..|. .|. ... | .| .. | |. | | . ....  |. .. .. |. ..||||| ..| . |..| ||..|..| | 
LGEMLRGKPMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMNQQKRKTLDQMMPQCCDDAIDLLKRLLVFNPKKRLTAEQALQHPYV
Kinase pmk-1.AA nmo 39-319 42 1.1e-93 288.49 In-house 5-292 (292) Show / Hide 
Range on Protein: 39-319
Range on HMM: 5-292/292
Sequence Identity: 42% (124 aa)

TPIGTGAYGTVCAAECTRSGTRVAIKKFNRPFQSIIHARRTYRELRLLRCMCHENIIDLLDVFTPNENVNDIEDVYFVSMLMGADLSNIL-KIQRLNDDH
 ||| ||.| | .    |.| |||.||.   ||... ..| .|||..|    |.|.. .||.  |  ...  ...| |  || .||  |.   | |  ||
RPIGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVLSALDILQP-PHKDFFQEIYVVTELMQSDLHKIIVSPQHLSSDH

IQFLVYQILRGLKYIHSADIIHRDLKPSNIAVNEDCELKILDFGLARQTDSE----MTGYVATRWYRAPEIMLNWMHYTQTVDVWSVGCILAELITGKTL
..  .|||||||||.|||.|.|||.|| |. || .| ||| ||||||  . .    ||  | | .||||||..   |||. ||.|||||| |||.  . |
VKVFLYQILRGLKYLHSANILHRDIKPGNLLVNSNCVLKICDFGLARVWEQDQSKHMTQEVVTQYYRAPEILMGARHYTSAVDIWSVGCIFAELLGRRIL

FPGSDHIDQLTRIMSVTGTPDEEFLKKISSEEARNYIRNLPKMTRRDFKRLFA-----QATPQAIDLLEKMLHLDPDRRPTAKEAMEHEYL
|     |.||  |. . |||  | . |   | |.. .   | .   ....|.      .||  |..|| .||| |||.|  .|.|..| ||
FQAQSPIQQLQMITDLLGTPSMEDM-KYACEGAKAHMLRMP-HKPPCLQVLYTLSSPDHATHEAVHLLCRMLHFDPDKRISCKDALAHPYL
Kinase pmk-1.AA S_TKc 35-319 29 4.9e-91 309.66 SMART 1-231 (231) Show / Hide 
Range on Protein: 35-319
Range on HMM: 1-231/231
Sequence Identity: 29% (90 aa)

YINLTPIGTGAYGTVCAAECTRSGTRVAIKKFNRPFQSIIHARRTYRELRLLRCMCHENIIDLLDVFTPNENVNDIEDVYFVSMLMGA---DLSNILKIQ
|  | .|| ||.|.|. .  ...| .||||. .         ....||...|.   |.||. |.|||         ...|.|  ...    ||  ..| .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDLFDYIKKR

R-------LNDDHIQFLVYQILRGLKYIHSADIIHRDLKPSNIAVNEDCELKILDFGLARQTDSEMTGYVATRWYRAPEIMLNWMHYTQ-TVDVWSVGCI
.       ..  |..|..|||...|.|.||  ||||||||.|| ..|  ..|| |||||||     | .. |.||.|||..    .|.   .|.||.|||
GRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCI

LAELITGKTLFPGSDHIDQLTRIMSVTGTPDEEFLKKISSEEARNYIRNLPKMTRRDFKRLFAQATPQAIDLLEKMLHLDPDRRPTAKEAME-------H
|.|...|...||   ..... ...                                         .|.|.|...|.|. ||..|||| ||..       |
LYEMLCGYPPFP---QMQMMFKKIG----------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCH

EYL
...
PWF
Kinase pmk-1.AA Pkinase 35-319 29 1.4e-87 302.09 Pfam 1-293 (293) Show / Hide 
Range on Protein: 35-319
Range on HMM: 1-293/293
Sequence Identity: 29% (93 aa)

YINLTPIGTGAYGTVCAAECTRSGTR--VAIKKFNRPFQSI---IHARRTYRELRLLRCMCHENIIDLLDVFTPNENVNDIEDVYFVSMLMGA-----DL
|  . .|| |..|.|   .|.. ||.  ||.|..... ..    ...||. .|..... ..|.||. |.|.|.         ..|.|  ...      ||
YHIGRKIGSGSFGCV--YKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-SEIQIMKRLNHPNIVRLYDWFED------KDHIYMVMEYCEGGLYVMDL

SNILK---IQRL--NDDHIQFLVYQILRGLKYIHSADIIHRDLKPSNIAVNEDCEL----KILDFGLARQ---TDSEMTGYVATRWYRAPEIMLNWMHYT
. ...     ..   .....| .|||||||.|.||  ||||||||.|| .......    || |||||.|    .| ||... |.||.|||. .   .|.
FDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDYNNS-MTTFCGTPWYMAPEVIRGGQYYG

QTVDVWSVGCILAELITGKTLFPGS----DHIDQLTRIMSVTGTPDEEFLKKISSEEARNYIRNLPKMTRRDFKRLFAQATPQAIDLLEKMLHLDPDRRP
. ||.||.||||.|...|...|||.    . .||. .|  . |.| ..   . .|.  .. .|  .    . ....   ... ..|.....|..|| .||
PKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H--F-HWTF-HNWSEECKDFIKWCLCKDPKKRP

TAKEAMEHEYL
||.....|...
TAEQILQHPWF
Kinase pmk-1.AA MAPK-Unclassified 35-184 45 2.1e-60 207.01 In-house 1-157 (575) Show / Hide 
Range on Protein: 35-184
Range on HMM: 1-157/575
Sequence Identity: 45% (72 aa)

YINLTPIGTGAYGTVCAAECTRS-GTRVAIKKFNRPFQSIIHARRTYRELRLLRCMCHENIIDLLDVFTPNENVN-DIEDVYFVSMLMGA---DLSNILK
|     || |||| || |  ... .  ||||| |. |.  . ..|. ||.|.|| . |.||| . |.|.. |  | .  |.| |  .|     ||  |.|
YEYQKNIGSGAYGQVCRAMDKKNQNQQVAIKKVNHIFHNHTDCKRVLREIRILRYLNHPNIIQIQDIFYNKELHNQEFDDIYIVMDYMQTSLFDLHQIIK

IQR--LNDDHIQFLVYQILRGLKYIHSADIIHRDLKPSNIAVNEDCELKILDFGLAR
     ... ||| . |||||||||.||| ||||||||||. .|.|| ..| |||..|
SNQDHWCHQHIQYFFYQILRGLKYLHSACIIHRDLKPSNLLINQDCSVRICDFGMSR
Kinase pmk-1.AA MAPK-Unclassified 185-319 34 5.4e-47 162.44 In-house 400-575 (575) Show / Hide 
Range on Protein: 185-319
Range on HMM: 400-575/575
Sequence Identity: 34% (60 aa)

QTDSEMTGYVATRWYRAPEIMLNWMHYTQTVDVWSVGCILAELITG-----------KTLFPGSD--------------------HIDQLTRIMSVTGTP
..  .||.||.|||||||||||    |.  || ||.|||.||..             . ||||.|                    |.||.  | .. |.|
HHCYHMTQYVVTRWYRAPEIMLSMHEYDTQVDIWSIGCIFAEMMQMYDRHNPTFSDHRPLFPGQDCFPITPDRNNDVDQGGFPHSHQDQIKMIFDYLGMP

DEEFLKKISSEEARNYIRNLPKMTRRDFKRLFAQATP----------QAIDLLEKMLHLDPDRRPTAKEAMEHEYL
.|| .  | .  || ||. . . |. .|. |.  ..|          ..||.. |||  .| .| || .| ||.| 
PEEDCNFITCDSARKYIQSFKCKTPVHFTDLMFCKAPGDDQIVRGNCECIDFVQKMLQFNPWKRITADQALEHPYF
Kinase pmk-1.AA TyrKc 35-319 24 4e-15 21.8 SMART 1-280 (280) Show / Hide 
Range on Protein: 35-319
Range on HMM: 1-280/280
Sequence Identity: 24% (78 aa)

YINLTPIGTGAYGTVCAAECTRSGTRVAIKKFNRPFQSIIHARRTYRELRLLRCM--CHENIIDLLDVFTPN-ENVNDIEDVYFVSMLMGA-DLSNILKI
   .  .| ||.|.|. .. .   . ||.|. .         .  .||.|...     |.||. |. | |   .|   || .. |  .|   || . |. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

QR--LNDDHIQFLVYQILRGLKYIHSADIIHRDLKPSNIAVNEDCELKILDFGLARQTDSE--------MT-------GY--VATRWYRAPEIMLNWMHY
 |  |. ..     .|| .|  |.||  .|||||   |. |.|.   || ||||.|  ...        .        |   .  ||. ||| . |   .
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM-APECI-NYGKF

TQTVDVWSVGCILAELIT-GKTLFPG-----------SDHIDQLTRIMSVTG----TPDEEFLKKISSEEARNYIRNLPKMTRRDFKRLFAQATPQAIDL
|   |||| |  . |. | |..  ||             ...|  | .                                         |  ...   ..
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS--------------------------------FVCCPDEMYQI

LEKMLHLDPDRRPTAKEAMEHEYL
 ..  | ||. ||| .|   ||..
MKQCWHEDPEDRPTFSEI--HECF
Kinase pmk-1.AA Pkinase_Tyr 143-232 35 1.9e-05 19.04 Pfam 118-213 (270) Show / Hide 
Range on Protein: 143-232
Range on HMM: 118-213/270
Sequence Identity: 35% (35 aa)

YQILRGLKYIHSADIIHRDLKPSNIAVNEDCELKILDFGLARQT-DSEMTGYVAT-------RWYRAPEIMLNWMHYTQTVDVWSVGCILAELIT-GKT
.|| .|. | .|  .|||||   |. |.|.   || ||||||   . .   |...       .|. ||| . .   .|   |||| |  . |..| |..
WQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWM-APECINYGK-FTTKSDVWSFGVLMWEIFTYGEQ
Kinase pmk-1.AA Pkinase_Tyr 35-65 22 0.025336 8.49 Pfam 1-35 (270) Show / Hide 
Range on Protein: 35-65
Range on HMM: 1-35/270
Sequence Identity: 22% (8 aa)

YINLTPIGTGAYGTVCAAECT----RSGTRVAIKK
 . .  .| ||.|.|. ....      .. ||.|.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKM