Gene W07G4.3 (Nematode worm)

W07G4.3

Species: Nematode worm
Alias: CE14688, aSWK241, W07G4.3
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: V:4.84, WormBase Physical Map location: V: 13044320-13039595

Classification

Group: Other
Family: SCY1

Sequence

Name Sequence Type Origin Length Description Download
W07G4.3.AA Protein Genbank 820 None Fasta, JSON
W07G4.3.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 189 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of W07G4.3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase W07G4.3.AA SCY1 29-162 24 1.1e-46 159.67 In-house 4-185 (337) Show / Hide 
Range on Protein: 29-162
Range on HMM: 4-185/337
Sequence Identity: 24% (45 aa)

FDRVSIGNSFKKAEPGELAT--------IFWDNRSSTLKQQAQKLKTMRHPNIITYLDSIELEGT--FYLVTEKCKPLELYLKEAGLTES----------
.. ... ...... . . ..         .|......||.||..||..|||||..|....| ...  .|...|...||| .||. . ..|          
HNGTKKYTGQECSVFVFDKKNIEKWHKDSWWEEICEFLKKQAKRLKRLRHPNILQYIHPLEESKDCMMYATEEIFQPLENVLKKWDNKKSCQTQKTQDVD

-----------------QKEFVVSWGMFQLLNALKFMH-EAKLSHENLRKG-VFVTAGGDWKIGG---------LHLVTGFT
                 ..|..|.||.||.|.||.|.| .....|.|...  .||...|||||||         .. |. ..
FGQNTQPQRPYHKKDWKLDELEVCWGIFQILDALSFLHNDCHMVHNNICPESIFVNKNGDWKIGGDDDDAGGWGMDFVCDIQ
Kinase W07G4.3.AA SCY1 163-226 16 5.9e-11 34.26 In-house 251-337 (337) Show / Hide 
Range on Protein: 163-226
Range on HMM: 251-337/337
Sequence Identity: 16% (14 aa)

SPQTDLNQLAIVLWEVFNGFNDAITRPQAP-------------------GKIPQRIHEL----YKKIGAQSAARLAVFSKISEYRLT
....|...| .. |.|.||... ||. . |                   ..||....|.    |... .|....   ......    
TWASDMFSLGCLIWWVYNGKKPQITCNSNPYSTFHRYMEQWNAMSHCWWDHIPKELQEHLGHCYCHLLHQDPTCRPDPQQFLQHCYF
Kinase W07G4.3.AA CAMK 65-130 18 3.7e-08 21.64 In-house 85-197 (425) Show / Hide 
Range on Protein: 65-130
Range on HMM: 85-197/425
Sequence Identity: 18% (21 aa)

LKT-------MRHPNIITYLDSIE----------------LEGT----FYLVT---EKCKPLEL------YLKEAGL------------TESQKEFVVSW
.|.       ..|||||  .. .|                   |    .|.|.   | |   ||      |..| |             .   .|  .. 
MKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTNDYETSKQVF-TKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARR

GMFQLLNALKFMHE
 . |.. |....|.
YFRQICSAVHYCHS
Kinase W07G4.3.AA Pkinase 65-135 24 1e-06 24.86 Pfam 54-131 (293) Show / Hide 
Range on Protein: 65-135
Range on HMM: 54-131/293
Sequence Identity: 24% (20 aa)

LKTMRHPNIITYLDSIELEGTFYLVTEKCKPL----ELY--LK---EAGL--TESQKEFVVSWGMFQLLNALKFMHEAKLSH
.| ..||||....|. | ..  |.|.| |       .|.  ..   . ..  .| .  |.    | |.| .|...|. .  |
MKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFY----MYQILRGLEYCHSMGIIH
Kinase W07G4.3.AA NEK 65-132 27 4e-06 17.94 In-house 58-139 (286) Show / Hide 
Range on Protein: 65-132
Range on HMM: 58-139/286
Sequence Identity: 27% (23 aa)

LKTMRHPNIITYLDSIELEG--TFYLVTEKCK---PLELYLKEAGLTESQ------KEFVVSWGMFQLLNALKFMHEA-----K
|| ..||||..| ||.. |.  ... | | |     |.  .|.  . . .       | .. . ..|.. |||.||.      |
LKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS--IKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRK
Kinase W07G4.3.AA MARK 65-91 40 7e-06 15.45 In-house 53-82 (262) Show / Hide 
Range on Protein: 65-91
Range on HMM: 53-82/262
Sequence Identity: 40% (12 aa)

LKTMRHPNIITYLDSIE--LEGT-FYLVTE
.| . ||||| ... ||   |.. .||. |
MKKLDHPNIIKLFHVIEQDTEQHQIYLIME
Kinase W07G4.3.AA Ciliate-E6 62-94 42 2.8e-05 13.14 In-house 1-33 (154) Show / Hide 
Range on Protein: 62-94
Range on HMM: 1-33/154
Sequence Identity: 42% (14 aa)

AQKLKTMRHPNIITYLDSIELEGTFYLVTEKCK
.| ||  .||||. |.||   |  .. | |.|.
IQNLKNCNHPNILKYMDSFQIENYYFIVMERCE
Kinase W07G4.3.AA Ciliate-E2 58-130 20 3.8e-05 13.6 In-house 60-178 (365) Show / Hide 
Range on Protein: 58-130
Range on HMM: 60-178/365
Sequence Identity: 20% (24 aa)

LKQQAQKLKTMR-------------------HPNIITYLDSIE--LEGTFYLVTEKCKPLELYL-----KEAGLTESQ-----KEFVVSWGMFQLLN---
..|. |... ||                   ||||| . .. .   . ..|||.| |.  .|.      |   . | .     .|. ..  | |.|.   
IEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFK

------------ALKFMHE
            ||...|.
TKAEFYIACIILALEYLHS
Kinase W07G4.3.AA CAMKL 65-99 32 5e-05 11.81 In-house 66-111 (297) Show / Hide 
Range on Protein: 65-99
Range on HMM: 66-111/297
Sequence Identity: 32% (15 aa)

LKTMR---HPNIITYLDSIELEGT------FYLVTEKCKPLE--LY
.| ..   |||||  .. || . .      .|||.| |   |  |.
MKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLF
Kinase W07G4.3.AA NEK1 65-89 44 5.3e-05 13.49 In-house 52-78 (276) Show / Hide 
Range on Protein: 65-89
Range on HMM: 52-78/276
Sequence Identity: 44% (12 aa)

LKTMRHPNIITYLDSIELEGT--FYLV
|. |.||||..| .| |..|    | |
LAKMKHPNIVKYKESFEENGCGILYIV
S_TKc W07G4.3.AA S_TKc 28-235 17 6.8e-05 -105.17 SMART 1-231 (231) Show / Hide 
Range on Protein: 28-235
Range on HMM: 1-231/231
Sequence Identity: 17% (47 aa)

FFDRVSIGN-SFKKAEPGELAT--------IFWDNRSSTLKQQAQKLKTMRHPNIITYLDSIELEGTFYLVTEKCK----PLELYLKEAG-------LTE
.     ||  .| |   .            |       ....  | ||  .||||....|...  . .|.|.| |      |  |.|. |       ..|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE

SQKEFVVSWGMFQLLNALKFMHEAKLSH-----ENLRKGVFVTAGGDWKIGGLHLVTGFTSPQTDLNQLAIVLW----EVFNGFND--------------
 .  |.    | |...||...|. .  |     ||.    ...     ||.   | . .       . .   .|    ||. |..               
-HARFY----MYQICCALEYCHSHGIIHRDLKPENI----LLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL-GYGKCKCDWWSCGCILYE

--AITRPQAPGKIPQRIHELYKKIGAQSAARLAVFSKISEY----RLTGGYLKN--------KFV
  .   |         .....||||  |   .   .|. ..    |.|   . .         ..
MLCGYPPFP------QMQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase W07G4.3.AA CMGC 65-135 17 0.000116 10.22 In-house 75-207 (513) Show / Hide 
Range on Protein: 65-135
Range on HMM: 75-207/513
Sequence Identity: 17% (24 aa)

LKTMR-----------------HPNIITYLDSIELEG-----------------TFYLVTEKCKP-LELYLKEAG----------LTESQ----------
|| ..                 |.||.. .|..  ..                  .|||.| .   |  |.|.            |.| .          
LKHLNKNHDPNWQRRDDPDNKHHNNIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPP

---KEFV--VSWGMFQLLNALK--FMHEAK--LSH
   | |.  .   |.|.|..||  ..| ..    |
HNIKYFMIHIR-YMYQILRGLKLKYCHSHWGNIIH
Kinase W07G4.3.AA NEK4 60-155 34 0.000218 11.88 In-house 47-146 (257) Show / Hide 
Range on Protein: 60-155
Range on HMM: 47-146/257
Sequence Identity: 34% (36 aa)

QQAQKLKTMRHPNIITYLDSIELEGT--FYLVTEKCKPLELYL-----KEAGLTESQKEFVVSWGMFQLLNALKFMHEAKLSHENLR-KGVFVTAGGDWK
. || |  ..||||..| .| | |     | |   |    ||      | . | |.|   || |   |   || .||| .  |  |.   .| |     |
HEAQLLSQLKHPNIVEYKESWEIENGQFLYIVMGFCEGGDLYRKLKQQKNQFLEEYQ---VVEW-FVQIAMALQYMHEKHILHRDLKTQNIFLTKKNIIK

IGGL
|| .
IGDF
HEAT W07G4.3.AA HEAT 312-342 25 0.002546 15.36 Pfam 1-31 (31) Show / Hide 
Range on Protein: 312-342
Range on HMM: 1-31/31
Sequence Identity: 25% (8 aa)

IVPCLCKLFGSPDRTTRVKLLERIDEFAPHL
|.|.|.|.. .||   |   .. . ....|.
ILPHLLKCLNDPDWEVREAACWCLGQLCEHC
HEAT W07G4.3.AA HEAT 351-381 25 0.000106 20.14 Pfam 1-31 (31) Show / Hide 
Range on Protein: 351-381
Range on HMM: 1-31/31
Sequence Identity: 25% (8 aa)

IFGNLTSGFLDTNPAVRESTVKAMVSLAEKL
|.  | ... |... |||........|.|..
ILPHLLKCLNDPDWEVREAACWCLGQLCEHC
HEAT W07G4.3.AA HEAT 390-421 18 20.412314 1.84 Pfam 1-31 (31) Show / Hide 
Range on Protein: 390-421
Range on HMM: 1-31/31
Sequence Identity: 18% (6 aa)

LMKYLARLQGGDEHGGIRTNTTICLGKIGHLI
.. .| ..   |..  .| ..  |||..   .
ILPHLLKCLN-DPDWEVREAACWCLGQLCEHC
HEAT W07G4.3.AA HEAT 430-460 19 0.200986 8.79 Pfam 1-31 (31) Show / Hide 
Range on Protein: 430-460
Range on HMM: 1-31/31
Sequence Identity: 19% (6 aa)

LISAFTRALKDPFAPSRMASVLALSATQQFY
..... ..|.|| .  |.|.. .|..  ...
ILPHLLKCLNDPDWEVREAACWCLGQLCEHC
HEAT W07G4.3.AA HEAT 469-499 29 3e-06 25.57 Pfam 1-31 (31) Show / Hide 
Range on Protein: 469-499
Range on HMM: 1-31/31
Sequence Identity: 29% (9 aa)

IVPSLIPLTCDPEKQVRDQAFKAIRGFLEKL
|.| |. . .||. .||..|....  ..|..
ILPHLLKCLNDPDWEVREAACWCLGQLCEHC