Gene Y50D7A.3 (Nematode worm)

Y50D7A.3

Species: Nematode worm
Alias: CE28993, Y50D7.Con462, Y50D7A.3, aSWK061
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: III:-27.95, WormBase Physical Map location: III: 254532-264874

Classification

Group: CAMK
Family: PHK

Sequence

Name Sequence Type Origin Length Description Download
Y50D7A.3.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 268 Kinase domain by global Sugen HMM Fasta, JSON
Y50D7A.3.AA Protein Sugen 485 None Fasta, JSON

Protein domain

Protein domains of Y50D7A.3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase Y50D7A.3.AA PHK 31-298 61 3.2e-224 751.19 In-house 1-273 (273) Show / Hide 
Range on Protein: 31-298
Range on HMM: 1-273/273
Sequence Identity: 61% (168 aa)

YESKEVLGRGLASTVRRCIEKGSGQHFAVKIVDIS-TEKQSENEAKRLLEETISEVEILRQLS---GHPSIIKIHDFYQTPSFLFAVFEMAPRGELFDVL
||.||.||||..|||||||.|..||.|||||.||. ||.||||||....|.|..|..||||..   |||.||..||||.|.||.|.||.|.|||||||.|
YEPKEILGRGVSSTVRRCIHKNTGQEFAVKIIDITGTEHQSENEAEHMREATRQEIHILRQVMEGEGHPNIIQLHDFYETNSFMFLVFDMMPRGELFDYL

NSTVTVSEKRARRLMKQLFDGVEYMHARDIVHRDLKLENILCIDEERIVISDFGFATRIPRGKKLRDLCGTPGYLAPETIRCQWY-DNAEGYSLEVDEWA
...||.|||..||.|.|||.||.||||..|||||||.|||||.|...|.|||||||.....|.|||.|||||||||||.|.|..| .|..||..|||.||
TEKVTLSEKKTRRIMRQLFEGVCYMHAHNIVHRDLKPENILCDDNMNIKISDFGFACQLQEGEKLRELCGTPGYLAPEMIKCSMYLENHPGYGQEVDMWA

LGVIMYTLLAGCAPFYHRKQLMMLRLIQQGKFEFRNEQWANITAEAKNLITQLLQVDATKRISSKECLAHEWM
.|||||||||||.||.||||.||||.|..||..|....|..|....|.||...||||...||...|||.|...
CGVIMYTLLAGCPPFWHRKQMMMLRMIMEGKYQFGSPEWDDISDTPKDLISKCLQVDPQQRITAEECLQHPFF
Kinase Y50D7A.3.AA CAMK 36-298 24 5.4e-111 359.0 In-house 1-425 (425) Show / Hide 
Range on Protein: 36-298
Range on HMM: 1-425/425
Sequence Identity: 24% (105 aa)

VLGRGLASTVRRCIEKGSG------------QHFAVKIVDISTEKQSE--------------------NEAKRLLEETISEVEILRQLSG------HPSI
.||||  ..|..||.| ..            |..|.||.| .  | ..                    ..  . ...  .|.||...|.|      || |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKIHDFYQTPSF-------------------LFAVF---EMAPRGEL----FDVLNST---------------VTVSEKRARRLMKQLFDGVEYMHARDI
||....|..|..                   .. |.   |... |||    || . .                  ..|. |||...|. ..|.|.| ..|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHRDLKLENILCIDEE-----------------RIVISDFGFATRIPR------------------------GKKLRDLCGTPGYLA-PETI----RCQW
||||||.||||. | .                  | |.|||||.....                        |.|... ||||.| | || .    .|..
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

YDN-----AEGYSLEVDEWALGVIMYTLLAGCAPFYHR-------------KQLMMLRLIQQGKFEFRNEQ------------WANITAE--------AK
. |      ..|. ..| |..|||.|..| |. |||.               .  ... |..||..|  ..            | .|. |        .|
Q-NATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

NLITQLLQVDATKRISSKECLAHEWM
.|| ..|||| .||.. ..||.|.||
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase Y50D7A.3.AA CAMK1 31-298 36 1.8e-98 286.86 In-house 1-276 (276) Show / Hide 
Range on Protein: 31-298
Range on HMM: 1-276/276
Sequence Identity: 36% (103 aa)

YESKEVLGRGLASTVRRCIEKGS---GQHFAVKIVD-ISTEKQSEN-EAKRLLEETISEVEILRQLS--GHPSIIKIHDFYQTPSFLFAVFEMAPRGELF
|| ....|||  |.|..|..| .   |...|.|. |  .  |.... . . .||    |.||....|   || |||....|......  | |    ||||
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQK-QEALEN---EIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELF

DVLNSTVTVSEKRARRLMKQLFDGVEYMHARDIVHRDLKLENILCIDE-ER--IV--ISDFGFATRIPRGK-KLRDLCGTPGYLAPETIRCQWYDNAEGY
|        .|| ||..|||... |||||...||||||| ||.|. |. |   |.  |.||| ....  .  .. . |||||| ||| . |     ...|
DRIVEKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKK---DKPY

SLEVDEWALGVIMYTLLAGCAPFYHRK-QLMMLRLIQQGKFEFRNEQWANITAE-AKNLITQLLQVDATKRISSKECLAHEWM
. ..| |  ||| |.|| |. |||    . .....|  ...|| . .| ||  . ||..|...| || .||.. ..||.| | 
DKACDMWSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase Y50D7A.3.AA S_TKc 31-298 30 7.4e-91 309.07 SMART 1-231 (231) Show / Hide 
Range on Protein: 31-298
Range on HMM: 1-231/231
Sequence Identity: 30% (87 aa)

YESKEVLGRGLASTVRRCIEKGSGQHFAVKIVDISTEKQSENEAKRLLEETISEVEILRQLSGHPSIIKIHDFYQTPSFLFAVFEMAPR--GELFDVLNS
||  ...|.|  ..|..|..|..|...|.||..               | ...|..||..  .|| |.|..|..|. ..|. |.|...   |.|||.. .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKK

TVT------VSEKRARRLMKQLFDGVEYMHARDIVHRDLKLENILCIDEERIVISDFGFATRIPRGKKLRDLCGTPGYLAPETIRCQWYDNAEGYSL-EV
  .       .| .||..|.|.....||.| . |.||||| ||||. .  .| |.|||.|...      . .|||| |.||| .         ||.  ..
RGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---------GYGKCKC

DEWALGVIMYTLLAGCAPFYHRKQLMMLRLIQQGKFEFRNEQWANITAEAKNLITQLLQVDATKRISSKECLA-------HEWM
| |..|.|.| .|.|. ||.   . ||...|               . |||..| ..||.| .||..  |.|.       |.|.
DWWSCGCILYEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Y50D7A.3.AA Pkinase 31-298 29 4.8e-85 293.65 Pfam 1-293 (293) Show / Hide 
Range on Protein: 31-298
Range on HMM: 1-293/293
Sequence Identity: 29% (91 aa)

YESKEVLGRGLASTVRRCIEKGSGQHFAVKIVDISTEKQSENEAKRLLEETISEVEILRQLSGHPSIIKIHDFYQTPSFLFAVFEMAPRG----ELFDVL
|. ....|.|  ..|..|..||.|. .||||.. ..|| ......|.|    ||..|.. | .|| |....|...... .  |.| .. |    .|||..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL----SEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYI

N--STVTV--SEKRARRLMKQLFDGVEYMHARDIVHRDLKLENILCIDEERI----VISDFGFATR--IPRGKKLRDLCGTPGYLAPETIRCQWYDNAEG
   .  ..  ||. ... |.|.. |.||.|.. |.|||||.||||. ..  |     |.|||.|    . ..  . ..||||.|.||| ||      ...
STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-----GGQY

YSLEVDEWALGVIMYTLLAGCAPFYHR------KQLMMLRLIQQGKFEFRNEQWANIT-----------------AEAKNLITQLLQVDATKRISSKECL
|. .|| |..|.|.| .| |  ||...       |. |...| .....|  ..| .|                   |.| .|. .|..| .||.. ...|
YGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQIL

AHEWM
 |.|.
QHPWF
Kinase Y50D7A.3.AA RAD53 31-298 32 3.4e-79 235.42 In-house 1-305 (305) Show / Hide 
Range on Protein: 31-298
Range on HMM: 1-305/305
Sequence Identity: 32% (101 aa)

YESKEVLGRGLASTVRRCIEKGSGQHFAVKIVDISTEK---QSENEAKRLLEETISEVEILRQLSGHPSIIKIHDFYQTP-SFLFAVFEMAPRGELFDVL
|   ..||.|  .||....||  .| .|.||.| ..      ..   .. ...   |||||. |. || ||.|.|...||   .. | | .  ||||. .
YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMN---EVEILKKLN-HPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKI

NSTVT----VSEKRARRLMKQLFDGVEYMHARDIVHRDLKLENILCIDEERIV------------------ISDFGFATRIPRGKKLRDLCGTPGYLAPE
 |  .    ..|  .... .|. |.| | | . |.||||| ||||| . .. .                  |.||| .  .  |  .. .|||| |.|||
VSNKRCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFVGEGSFMKTMCGTPQYVAPE

TIRCQ---WYDNAE------GYSLEVDEWALGVIMYTLLAGCAPFY-HRKQ-----LMMLRLIQQGKFEFRNEQWANITAEAKNLITQLLQVDATKRISS
 |. .    |.  |      ||. .|| | .|.| |..|.|  ||  ...|      .   ...|||..|  ..|. |. |||.|| ..|.|| .||.. 
VITSKGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTI

KECLAHEWM
.| | | ||
DEALNHPWM
Kinase Y50D7A.3.AA RSK 33-298 30 1.2e-73 250.96 In-house 1-278 (278) Show / Hide 
Range on Protein: 33-298
Range on HMM: 1-278/278
Sequence Identity: 30% (88 aa)

SKEV--LGRGLASTVRRCIEKGSGQHFAVKIVDISTEKQSENEAKRLLEETISEVEILRQLSGHPSIIKIHDFYQTPSFLFAVFEMAPRGELFDVLNSTV
 |.   .| |  ...|.|. . .||..|.|... .. .|..      .. |  |..||    .|| |.. |. .||.. |. . |  . ||||. |   .
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKD----TRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEK

T---VSEKRARRLMKQLFDGVEYMHARDIVHRDLKLENILCID---EERIVISDFGFATR-IPR-GKKLRDLCGTPGYLAPETIRCQWYDNAEGYSLEVD
.    ||..|.  | ..   ||..| ..|.|||||.||||  |   |..|...||||.    .. ....   |.|  |.||| ..       .|..  .|
HFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRAN--QQGGHDKACD

EWALGVIMYTLLAGCAPFYH---RKQLMMLRLIQQGKFEFRNEQWANITAEAKNLITQLLQVDATKRIS-----SKECLAHEWM
 | |||.||..|.|| ||..     .   .. ||.||| .. . |.....|||.||...|..|  ||..      .| ..|.|.
WWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase Y50D7A.3.AA CDPK 31-298 35 1.8e-73 224.78 In-house 1-271 (271) Show / Hide 
Range on Protein: 31-298
Range on HMM: 1-271/271
Sequence Identity: 35% (101 aa)

YESKEVLGRGLASTVRRCIEK-GSGQHF-AVKIVDISTEKQSENEAKRLLEET-ISEVEILRQLSGHPSIIKIHDFYQTPSFLFAVFE--MAPRGELFDV
|  |.|||.|  ..||....| ...|   |.||.  |  |..|       ..  . |.|||.||  || ||||  |||   . . |.|  .   |||||.
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQ------QQQFFNEIEILKQLD-HPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDY

LNSTVTVSEKRARRLMKQLFDGVEYMHARDIVHRDLKLENIL-CIDEE------RIVISDFGFATRIPR-----GKKLRDLCGTPGYLAPETIRCQWYDN
  ..   .|| |.  |.|..  | |.| . ||||||| |||| .....       |.. |.| ... .      .||... |||| |.||| .. . |. 
IIEKGHFTEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKK-YNE

AEGYSLEVDEWALGVIMYTLLAGCAPFYHRKQLMMLRLIQQGKFEFRNEQWANITAEAKNLITQLLQVDATKRISSKECLAHEWM
      ..| | .|||.|.|| |  ||| . .   .  .. ||..|  ..|..|. |||.|| ..|..|  ||.|. ..|.| |.
------KCDIWSCGVILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF
Kinase Y50D7A.3.AA CAMKL 31-298 27 4.2e-72 229.35 In-house 1-297 (297) Show / Hide 
Range on Protein: 31-298
Range on HMM: 1-297/297
Sequence Identity: 27% (86 aa)

YESKEVLGRGLASTVRRCIE-KGSGQHFAVKIVDISTEK-QSENEAK-------RLLEETISEVEILRQLS--GHPSIIKIHDFYQTPSF------LFAV
|.  ..||.|  ..|. ..  .  |.. |.||.|..  .    ....       . .     |..|...|.  .|| |||... ..||..      .. |
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV

FEMAPRGE--LFDVLNST----VTVSEKRARRLMKQLFDGVEYMHARDIVHRDLKLENILCIDEER---IVISDFGFATR-----IPRGKKLRDLCGTPG
 | .. ||  ||| . .        .|. |||. .|. ..|.|.| ..|||||.|.|||| .||     | |.||||..      ...|.||.  ||.| 
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENIL-LDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPP

YLAPETIRCQWYDNA--EGYS-LEVDEWALGVIMYTLLAGCAPFYHR-----KQLMMLRLIQQGKFEFRNE-QWANITAEAKNLITQLLQVDATKRISSK
| ||| .      .   . |   .|| |..|||.|... |  ||        ..    .|  . .    ..  |  .  ....|| ..|||. .||.. .
YMAPEIF------QGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIH

ECLAHEWM
. . |.||
QIMNHPWM
Kinase Y50D7A.3.AA CAMK-Unique 31-298 24 7.9e-70 229.64 In-house 1-363 (363) Show / Hide 
Range on Protein: 31-298
Range on HMM: 1-363/363
Sequence Identity: 24% (92 aa)

YESKEVLGRGLASTVRRCIEKGSGQHFAVKIVDISTEKQSENEA------------KRLLEETISEVEILRQLSGHPSIIKIHDF----YQTPS------
|.  ...| |  . |..|. .  |  .|.|.|   | . . . .            ||.  ..  |..|.. .. || |||. |.    ....       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVD-HPNIIKLYDWNNPIFCDRKYPLCDL

---------FLFAVFEMAPRGELFDVLNS--------------------TVTVSE--KRARRLMKQLFDGVEYMHARDIVHRDLKLENILCIDE------
          .. | | .. |.|||....                        ||    ....| .|   |.|||  ||||||||||||.   .      
IIKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNH

----------ERIVISDFGFATRIPRGKKLR---DLCGTPGYLAP--------------ETIRCQWYDNAEGYSLEV----DEWALGVIMYTLLAGCAPF
           .|...||| .. .   |.       |||| |.||              |.|      |. .|.  .    | |.||||||..| || ||
HRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVI------NMQCYDQQCSPASDIWSLGVIMYYMLCGCPPF

YHRKQL--------MMLRLIQQGKF-EFRNEQWAN---ITAEAKNLITQLLQVDATKRISSKECLAHEWM
..              .. | .|.. .|....|     |. |||........||  .|.|.|| | |.| 
DCECEDRDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase Y50D7A.3.AA Ciliate-E2 31-298 24 1.8e-69 237.09 In-house 1-365 (365) Show / Hide 
Range on Protein: 31-298
Range on HMM: 1-365/365
Sequence Identity: 24% (93 aa)

YESKEVLGRGLASTVRRCIEKGSGQHFAVKIVDIST---------EKQSENEAKRL----LEETISEVEILR---------------QLSGHPSIIKIHD
|.  ...|.|  ..|..|  .  .. || || |             |... . |..    .|.. .|  |.|               ..  || |||...
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

FYQ--TPSFLFAVFEMAPRGELFDVLN------------STVTVSEKRARRLMKQLFD---------------GVEYMHARD-IVHRDLKLENILCIDEE
..|  . . .. |.| .  |.||| ..                 .|| ....|||...               ..||.| .  |.|||.|.||||     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

RIVISDFGFATRIP-----------RGKKLRDL----------------------CGTPGYLAPETIRCQWYDN---AEGYSLEVDEWALGVIMYTLLAG
 | |.|||.....            .....                         ||||||.||| .. . |||    .||. ..| |.||||.| .| |
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG

CAPFYHRKQLMMLRLIQQGKFEFRNE--------------QWANITAEAKNLITQ----LLQVDATKRIS-SKECLAHEWM
  ||        .. |.|.|..|...               | ... |.|.|| .    .||.|  |||.  ...| |.|.
KPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase Y50D7A.3.AA MSK 34-298 33 4.2e-67 225.89 In-house 1-277 (277) Show / Hide 
Range on Protein: 34-298
Range on HMM: 1-277/277
Sequence Identity: 33% (94 aa)

KEVL---GRGLASTVRRCIEKGSGQHFAVKIVDISTEKQSENEAKRLLEETISEVEILRQLSGHPSIIKIHDFYQTPSFLFAVFEMAPRGELFDVLNSTV
..||   | |  ...|.|  . .|. .|.||.   |  |.    ... |.|  |. .|. . .|| | . |. .|... .. | | .  ||||  . .  
LKVLGTGGYGKFFICRKCVHHDTGKLYAMKILSKATVVQK----RKTAEHTQTERQCLEMCQQHPNIVNLHYAFQDQCHTYLVMEYCNGGELFTHIRKRE

TVSEKRARRLMKQLFDGVEYMHARDIVHRDLKLENILCIDE---ERIVISDFGFATRIPRG--KKLRDLCGTPGYLAPETIRCQWYDNAEGYSLEVDEWA
  .|...|  | .|   |..|| . |.|||||.||||  ||    .....|||||   |..  ...   |.|  | ||| .|   | . .||.  .| | 
HFDESECRMIMRELVMAVDHMHQKGIIHRDLKPENILFDDEEDNGHVKLIDFGFARLFPQDEEWRMKSPCFTLHYMAPEMLRRG-YAQDGGYDEACDWWS

LGVIMYTLLAGCAPFY----HRK-----QLMMLRLIQQGKFEFRNEQWANITAEAKNLITQLLQVDATKRISSKECLAHEWM
||||.||.| |. ||      |.     .    . |. |.| |. ..| |. ..||.||..||..|  || .  . .|||| 
LGVILYTMLTGQVPFQQNEDDRQHSCNSHHEIMKRICKGEFSFPGMAWQNMSPDAKDLIQWLLTKDPKKRLGMNDLRAHEWK
Kinase Y50D7A.3.AA TyrKc 31-298 22 3.6e-12 -25.99 SMART 1-280 (280) Show / Hide 
Range on Protein: 31-298
Range on HMM: 1-280/280
Sequence Identity: 22% (67 aa)

YESKEVLGRGLASTVRRCIEKGSGQHFAVKIVDISTEKQSENEAKRLLEETISEVEILRQL-SGHPSIIKIHDFYQTP-------SFLFAVFEMAPRGEL
 . ...||.|   .|.... |   .  ||| .  ..           .|. ..| .|...|   || |....    ..         |. |.| .| | |
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDL

FDVL-NSTVTVSEKRARRLMKQLFDGVEYMHARDIVHRDLKLENILCIDEERIVISDFGFATRIPRG-----KKLRDLC----GTPG-----YLAPETIR
 | | ..  ... |     . |  .| || | . ..||||   |.|  .. .. ||||| .  |  .      |         |. .      .|||.| 
KDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-

CQWYDNAEG-YSLEVDEWALGVIMYTLLAGCAPFYHR-KQ--LMMLRLIQQGKFEFRNEQWAN--------ITAEAKNLITQLLQVDATKRISSKECLAH
       .| .. . | |. || |. ..  ... |    |  .   ..|.. |  .| .| .|         ..|  ....|  . |. .| . .|.  |
------NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--H

EWM
| .
ECF