Gene ZC404.9 (Nematode worm)

ZC404.9

Species: Nematode worm
Alias: CE07599, aSWK304, ZC404.9
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: V:-2.15, WormBase Physical Map location: V: 6795268-6791051

Classification

Group: STE
Family: STE20
Subfamily: KHS

Sequence

Name Sequence Type Origin Length Description Download
ZC404.9.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 259 Kinase domain by global Sugen HMM Fasta, JSON
ZC404.9.AA Protein Genbank 829 None Fasta, JSON

Protein domain

Protein domains of ZC404.9.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase ZC404.9.AA KHS 15-273 77 3.4e-196 658.07 In-house 1-258 (258) Show / Hide 
Range on Protein: 15-273
Range on HMM: 1-258/258
Sequence Identity: 77% (202 aa)

YELLQRVGSGTYGEVYKARDIRSDSLAAVKVVKLEAGDNFAVIQQEIMVIRECSHPNIIAYFGSYIRRDRLWIVMEYCGGGSLQDIYHLTGPLSELQIAF
|||||||||||||.|||||||.||.||||||.|.|.||.|||||||||....|.||||.||||||.|||.|||.||||||||||||||.||||||||||.
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKMEPGDDFAVIQQEIMMMKDCRHPNIVAYFGSYLRRDKLWICMEYCGGGSLQDIYHVTGPLSELQIAY

VCRETLRGLNYLHNMGKIHRDIKGANILLSSSGDVKLADFGVAAQITATIGKRKSFIGTPYWMAPEVACVEKRGGYGMQCDVWATGITAIELGECQPPLF
||||||.||.|||.|||.|||||||||||...||||||||||.|||||||.|||||||||||||||||.||..|||...||.||.|||||||.|.|||.|
VCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWAVGITAIELAELQPPMF

DLHPMQVLYLMTKSGYKPPHLKDKHRWTPLFHDFVRQCLTKNPKKRPSPEKLLTSHPFV
|||||..|.|||||...||.|||||.|.. ||.||...|||||||||..||||. ||||
DLHPMRALFLMTKSNFQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQ-HPFV
Kinase ZC404.9.AA STE20 15-273 49 7.50000000001e-160 537.34 In-house 1-288 (288) Show / Hide 
Range on Protein: 15-273
Range on HMM: 1-288/288
Sequence Identity: 49% (142 aa)

YELLQRVGSGTYGEVYKARDIRSDSL----AAVKVVKLEAG----DNFAVIQQEIMVIRECSHPNIIAYFGSYIRR----DRLWIVMEYCGGGSLQDIYH
||||...|.|.||.||||...... .    .|.|...||      | .  ||.|| . ..| ||||..|.|||..     | |||||||||||||.||..
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

---LTG------PLSELQIAFVCRETLRGLNYLHNMGKIHRDIKGANILLSSSGDVKLADFGVAAQITA----TIG-KRKSFIGTPYWMAPEVACVEK--
    .|      |..| |||..|||.|.||.|||....||||||..||||...|.||||||||.||.|     |.. ||..|.|||||||||| . ..  
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGP

RGGYGMQCDVWATGITAIELGECQPPLFDLHPMQVLYLMTKSGYKPPHLKD--KHRWTPLFHDFVRQCLTKNPKKRPSPEKLLTSHPFV
..||.  ||.|. ||||||. | .||.||.|||.......|.. .||.|||  .|.|.| ||||| .||.|.|.|||....||. |||.
DKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLK-HPFI
Kinase ZC404.9.AA STE 15-273 32 5.9e-129 434.72 In-house 1-359 (359) Show / Hide 
Range on Protein: 15-273
Range on HMM: 1-359/359
Sequence Identity: 32% (119 aa)

YELLQRVGSGTYGEVYKARDI------RSDSL---------AAVKVVKLEAG-----------------DNFAVIQQEIMVIRECS--HPNIIAYFGSYI
.|.....|.|..|.||||...      ... .          |.|...||                   ...  |..|| . ..|.  ||||. |.|.|.
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

R-------RDRLWIVMEYCGGGSLQDIYHLT--------------GPLSELQIAFVCRETLRG-LNYLHNMGKIHRDIKGANILLSSSGDVKLADFGVAA
.       .| |||.|||..|||| ||.. .              ....| |||..||..|.| |.|||....||||||.|||||     |||.||||..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

QITA---------------TIG-KRKSFIGTPYWMAPEVACVEK---RGGYGMQCDVWATGITAIELGECQPPLFDLHPMQVLYLMTKSG----------
|.|                |.. ||..|.||| ||||||   ..   ..||. .||.|  |.|.||. . .||..|.|||..........          
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---YKPPHLKD-----------------KHRWTPLFHDFVRQCLTKNPKKRPSPEKLLTS-HPFV
    .|| |.|                 .|.|.| |.||...||.|.|.|||....|| | |||.
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase ZC404.9.AA YSK 15-273 48 3.2e-119 360.72 In-house 1-257 (257) Show / Hide 
Range on Protein: 15-273
Range on HMM: 1-257/257
Sequence Identity: 48% (126 aa)

YELLQRVGSGTYGEVYKARDIRSDSLAAVKVVKLE-AGDNFAVIQQEIMVIRECSHPNIIAYFGSYIRRDRLWIVMEYCGGGSLQDIYHLT--GPLSELQ
.  . ..| | .|||||. | |     |.|.. || | |    |||||..  .|  |.|  |.||| .   |||.||||||||. |       |.. | .
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIEDIQQEIQFLSQCDSPYITKYYGSYLKDTKLWIIMEYCGGGSCLDLMKPKYVGQFDEKY

IAFVCRETLRGLNYLHNMGKIHRDIKGANILLSSSGDVKLADFGVAAQITATIGKRKSFIGTPYWMAPEVACVEKRGGYGMQCDVWATGITAIELGECQP
||.. || | || |||   ||||||| ||.||| .|||||.|||||.||| |  ||  |.|||||||||| | |   .|    |.|  ||||.|.   .|
IAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNTFVGTPYWMAPEVICQE-VSYYDFKADIWSLGITAYEMAKGEP

PLFDLHPMQVLYLMTKSGYKPPHLKDKHRWTPLFHDFVRQCLTKNPKKRPSPEKLLTSHPFV
|. |.||| |. |  |.  .|| |...  ..  | .||  || |.|..||| . || .| |.
PYCDYHPMRVMFLIPKN--NPPKLEGR-SYSKMFKEFVECCLNKDPEQRPSAKELL-KHKFI
Kinase ZC404.9.AA MST 15-273 45 9.3e-113 359.75 In-house 1-254 (254) Show / Hide 
Range on Protein: 15-273
Range on HMM: 1-254/254
Sequence Identity: 45% (118 aa)

YELLQRVGSGTYGEVYKARDIRSDSLAAVKVVKLEAGDNFAVIQQEIMVIRECSHPNIIAYFGSYI--RRDRLWIVMEYCGGGSLQDIYHLTG-PLSELQ
.... . | | || |||| .. .... |.|.|.   .| .  |  ||    .|  ..|  |.|||.      .||||||||.||. ||  .|. .|.| |
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPV-NED-LQEIIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMKITQRTLNEQQ

IAFVCRETLRGLNYLHNMGKIHRDIKGANILLSSSGDVKLADFGVAAQITATIGKRKSFIGTPYWMAPEVACVEKRGGYGMQCDVWATGITAIELGECQP
|| ... ||.|| |||.. ||||||| .||||.  |  |||||||..| | | .|| ..|||||||||||       .|    | |. ||||||. |  |
IACILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMAKRNTVIGTPYWMAPEVI---QEIKYDCKADIWSLGITAIEMAEGMP

PLFDLHPMQVLYLMTKSGYKPPHLKDKHRWTPLFHDFVRQCLTKNPKKRPSPEKLLTSHPFV
|..|.||| .. .  ..   || .|| ..| . | |||..||.||| .|.. | || .|||.
PYSDIHPMRAMFMIPQKP--PPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLL-QHPFI
Kinase ZC404.9.AA PAKA 15-273 40 9.3e-101 341.04 In-house 1-260 (260) Show / Hide 
Range on Protein: 15-273
Range on HMM: 1-260/260
Sequence Identity: 40% (109 aa)

YELLQRVGSGTYGEVYKARDIRSDSL--AAVKVVKLEAGDNFAVIQQEIMVIRECSHPNIIAYFGSYIRRDRLWIVMEYCGGGSLQDIYHLTG-----PL
|. .. .| |  ||||.| .|.  .    |.|. .... .    |  || | .|| |.||. |  ||.  | ||.|||| .||.| |.   .      ..
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKNQPKKELIINEILVMKECKHKNIVNYIDSYLVDDELWVVMEYMEGGCLTDVITQCCNIQCNYM

SELQIAFVCRETLRGLNYLHNMGKIHRDIKGANILLSSSGDVKLADFGVAAQITATIGKRKSFIGTPYWMAPEVACVEKRGGYGMQCDVWATGITAIELG
.| |||.||||.|.||...|. . ||||||  |||| . |.||..||| .||.|    ||..  ||||||||||    .|  |.   |.| .|| |||. 
DEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVI---RRKQYDEKVDIWSLGIMAIEMI

ECQPPLFDLHPMQVLYLMTKSGYKPPHLKDKHRWTPLFHDFVRQCLTKNPKKRPSPEKLLTSHPFV
| .||  .  |   .|| .. |   |..||...|.. |.||. .|| .....|.| ..||. ||| 
EGEPPYLNEPPLRAMYLIATNGK--PDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLH-HPFL
Kinase ZC404.9.AA S_TKc 15-273 31 6.8e-98 332.45 SMART 1-231 (231) Show / Hide 
Range on Protein: 15-273
Range on HMM: 1-231/231
Sequence Identity: 31% (86 aa)

YELLQRVGSGTYGEVYKARDIRSDSLAAVKVVKLEAGDNFAVIQQEIMVIRECSHPNIIAYFGSYIRRDRLWIVMEYCGG--GSLQDIYHLTGP------
||.|. .|.|..|.|||.|..... . |.|..|         |..|| . ..  ||||. .....   |.|..|||||.|  |.| |. .  |.      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LSELQIAFVCRETLRGLNYLHNMGKIHRDIKGANILLSSSGDVKLADFGVAAQITATIGKRKSFIGTPYWMAPEVACVEKRGGYGM-QCDVWATGITAIE
..| ...|........|.|.|..| ||||.| .||||..   .|..|||.|.|.       ..|.|||..|||||       |||   ||.|. |.. .|
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL------GYGKCKCDWWSCGCILYE

LGECQPPLFDLHPMQVLYLMTKSGYKPPHLKDKHRWTPLFHDFVRQCLTKNPKKRPSPEKLLT------SHPFV
.   .||    ...... ..                .| . ||.|.||.|.|.|||.  ..|.      .||..
MLCGYPPFP--QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase ZC404.9.AA MSN 15-273 47 1.3e-92 306.13 In-house 1-265 (265) Show / Hide 
Range on Protein: 15-273
Range on HMM: 1-265/265
Sequence Identity: 47% (129 aa)

YELLQRVGSGTYGEVYKARDIRSDSLAAVKVVKLEAGDNFAVIQQEIMVIRECS-HPNIIAYFGSYIR------RDRLWIVMEYCGGGSLQDIYHLT--G
.|| . || ||||.||| |  .  .|||.||....  |.   |.||| ...  | | ||..|.| .|.      ...||.|||.|| ||. |. . |   
FELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVRE-DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGHDHQLWMVMEFCGAGSVTDLVKMTKGQ

PLSELQIAFVCRETLRGLNYLHNMGKIHRDIKGANILLSSSGDVKLADFGVAAQITATIGKRKSFIGTPYWMAPEV-ACVEK-RGGYGMQCDVWATGITA
 | |  ||..||| |||| .||    ||||||| |.||  . .||| ||||.||.  |.|.| .|||||||||||| || |. .  | .. |.|. ||||
SLKEDWIAYICREILRGLAHLHQHKVIHRDIKGQNVLLTHNAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSVGITA

IELGECQPPLFDLHPMQVLYLMTKSGYKPPHLKDKHRWTPLFHDFVRQCLTKNPKKRPSPEKLLTSHPFV
||. | |||| |.|||. |.|. .    ||.||  ..|.  ||.|. .|| || ..||. |..|  |||.
IEMAEGQPPLCDMHPMRALFLIPRN--PPPKLK-SKKWSKKFHNFMEKCLIKNYHQRPYTEQMLK-HPFI
Kinase ZC404.9.AA SLK 15-273 40 8.7e-86 289.4 In-house 1-259 (259) Show / Hide 
Range on Protein: 15-273
Range on HMM: 1-259/259
Sequence Identity: 40% (105 aa)

YELLQRVGSGTYGEVYKARDIRSDSLAAVKVVKLEAGDNFAVIQQEIMVIRECSHPNIIAYFGSYIRRDRLWIVMEYCGGGSLQDIY-HLTGPLSELQIA
.|..  .| | .| ||||..   . .|| |..... ...      || .. || ||||.  ...|   ..||...|.|.|| .  |   |  || | ||.
WEIIGELGDGAFGKVYKAQHKEQKVFAAAKMIEIKDEEELEDYMVEIDILSECKHPNIVKLYEAYYYDNKLWMMIEFCDGGAVDNIMVELEHPLTEDQIQ

FVCRETLRGLNYLHNMGKIHRDIKGANILLSSSGDVKLADFGVAAQITATIGKRKSFIGTPYWMAPEVACVE--KRGGYGMQCDVWATGITAIELGECQP
.||.... .||.||.   ||||.|  |||.   |||.||||||.|. . |. || .||||||||||||   |  |   | .. |.|. ||| ||. .  |
YVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLADFGVSAKNKHTMQKRDTFIGTPYWMAPEVVMCETFKDQPYDYKADIWSLGITLIEMAQMEP

PLFDLHPMQVLYLMTKSGYKPPHLKDKHRWTPLFHDFVRQCLTKNPKKRPSPEKLLTSHPFV
|  .. || ||  . ||   || |.   .|.  |.||...|| |.|..|.. ..|.  |..|
PHHEMNPMRVLLKIQKS--EPPTLEQPSHWSKEFKDFLKKCLVKDPQNRWTTAQLMQ-HQWV
Kinase ZC404.9.AA PAKL 15-273 40 5.1e-83 282.12 In-house 1-256 (256) Show / Hide 
Range on Protein: 15-273
Range on HMM: 1-256/256
Sequence Identity: 40% (107 aa)

YELLQRVGSGTYGEVYKARDIRSDSLAAVKVVKLEAGDNFAVIQQEIMVIRECSHPNIIAYFGSYIRR-DRLWIVMEYCGGGSLQDIYHLTG-PLSELQI
.|.    | | || ||||    .    |.||  .        |. || .   |  |||. ||||     . .|| |.||  ||  |.  ...  | | ||
FEFQEKLGQGSYGSVYKAIHKDTNFPLAIKVIEIKESNEIKDIEKEIQILKKCKCPNIVSYFGSIQQKLNHYWILMDYCSLGSINDMMESCCKTLNEKQI

AFVCRETLRGLNYLHNMGKIHRDIKGANILLSSSGDVKLADFGVAAQITATIG-KRKSFIGTPYWMAPEVACVEKRGGYGMQCDVWATGITAIELGECQP
... . ||.|| |||  . |||||| |||||.  ..||.|||||  |.  . .   .. ||||||||||.    ..  |   ||.|  ||||||. .  |
SVILQQTLKGLHYLHSKNIIHRDIKAANILLNEDCQVKIADFGVSQQLQDEYDGQANQMIGTPYWMAPEII---NKQNYNNKCDIWSLGITAIEMADGFP

PLFDLHPMQVLYLMTKSGYKPPHLKDKHRWTPLFHDFVRQCLTKNPKKRPSPEKLLTSHPFV
|. |. ||  .|        || ... . | |.| ||. ||..| | ||.||  ||. ||| 
PHYDMPPMRAMYMIPNWP--PPTFSNPKHWSPCFNDFLAQCCVKDPEKRWSPIDLLC-HPFI
Kinase ZC404.9.AA NinaC 15-273 41 1.8e-81 276.97 In-house 1-267 (267) Show / Hide 
Range on Protein: 15-273
Range on HMM: 1-267/267
Sequence Identity: 41% (112 aa)

YELLQRVGSGTYGEVYKARDIRSDSLAAVKVVKLEAGDNFAVIQQEIMVIRE-CSHPNIIAYFGSYIRRDR-----LWIVMEYCGGGSLQDI----YHLT
.|    .| |||| |.|. . .....||||.      |    |  |  . |. |.|||.. ..| | . |.     ||.||||| |||  |.      . 
WEIYETIGKGTYGKVFKVKNKDNGQIAAVKIQHYIH-DHDEEIEAEYNILRDYCDHPNVVRFYGMYYKKDKCNGDQLWFVMEYCNGGSVTDMVKGLLKCG

GPLSELQIAFVCRETLRGLNYLHNMGKIHRDIKGANILLSSSGDVKLADFGVAAQITATIGKRKSFIGTPYWMAPEV-ACVEKR-GGYGMQCDVWATGIT
  ..|  ||.. .|...||  ||.   ||||.|| ||||   | ||| |||| ||.. | ..|   .|||.|||||| || . .   |   ||||. |||
RRMREEHIAYILHEACMGLQHLHCNHVIHRDVKGNNILLTTEGGVKLCDFGVSAQLDSTRHRRNTCVGTPCWMAPEVIACMQQYDPDYDARCDVWSLGIT

AIELGECQPPLFDLHPMQVLYLMTKSGYKPPHLKDKHRWTPLFHDFVRQCLTKNPKKRPSPEKLLTSHPFV
|||||   ||..|.|||. ..        || |     |   | ||. |||.|.  |||.   .|  |||.
AIELGDGDPPFADMHPMRAMFKIPRNP--PPTLMHPENWCQEFNDFISQCLEKDYEKRPMMVHMLE-HPFI
Kinase ZC404.9.AA Pkinase 15-273 30 4.7e-80 277.07 Pfam 1-293 (293) Show / Hide 
Range on Protein: 15-273
Range on HMM: 1-293/293
Sequence Identity: 30% (91 aa)

YELLQRVGSGTYGEVYKARDIRSDSLAAVKVVKLEAGDNFAVIQQ-----EIMVIRECSHPNIIAYFGSYIRRDRLWIVMEYCGGG----SLQDIYH--L
|......|||..|.|||.... .  . |||..|.. ...  . |.     || . ....||||. ..... ..|....|||||.||    .| |. .   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

TGPL--SELQIAFVCRETLRGLNYLHNMGKIHRDIKGANILLSSSGDV----KLADFGVAAQI-TATIGKRKSFIGTPYWMAPEVACVEKRGGYGMQCDV
 |..  || .. |.....||||.|.|.|| ||||.| .|||... |..    |..|||.|.|. .   .  ..| |||..|||||  . .. .||  .|.
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEV--IRGGQYYGPKVDM

WATGITAIELGECQPPLFDL----HPMQVLYLMTKSGYKPPHLKDK-------------------HRWTPLFHDFVRQCLTKNPKKRPSPEKLLTSHPFV
|. |.. .|.   .||  .     . .  .... . ...|.|                       |.|.. . ||.. ||.|.|||||..| .|  ||..
WSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQIL-QHPWF
Kinase ZC404.9.AA Pkinase_Tyr 15-157 27 1.1e-22 77.39 Pfam 1-158 (270) Show / Hide 
Range on Protein: 15-157
Range on HMM: 1-158/270
Sequence Identity: 27% (44 aa)

YELLQRVGSGTYGEVYKARDI----RSDSLAAVKVVKLEAGDN---FAVIQQEIMVIREC-SHPNIIAYFGSYI-RRDR--LWIVMEYCGGGSLQDIYHL
 ....  |.| .|||||..        .   |||..|  | .     .   .|. . ..  .||||. . |  . ...   ..|||||. .|.| |  . 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

----TGPLSELQIAFVCRETLRGLNYLHNMGKIHRDIKGANILLSSSGDVKLADFGVA
     .||.  ..   |..  .|..||.... ||||.   |.|..... || .||| |
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase ZC404.9.AA TyrKc 15-273 24 9.6e-18 64.15 SMART 1-280 (280) Show / Hide 
Range on Protein: 15-273
Range on HMM: 1-280/280
Sequence Identity: 24% (72 aa)

YELLQRVGSGTYGEVYKARDIRSDSLAAVKVVKLEAGDNFAVIQQEIMVIREC--SHPNIIAYFGSYIRR-------DRLWIVMEYCGGGSLQDIYHLTG
 .|..  |.| .|||||.. .      |||..| .|    . . .|. . ..   .||||.. .|  .         . |.|||||. .|.|.|  . ..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

P-LSELQIAFVCRETLRGLNYLHNMGKIHRDIKGANILLSSSGDVKLADFGVAAQITAT--------IGKRKSFIGTP-----YWMAPEVACVEKRGGYG
| |.  .    |    .| .||| .. ||||.   |.|... . || .||| .  |.            . |.  |.       |||||.    . | . 
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI---NYGKFT

MQCDVWATGIT---AIELGECQPPL---FDLHPMQVLYLMTKSGYKPPHLKDKH-----RWTPLFHDFVRQCLTKNPKKRPSPEKLLTSHPFV
 . |||. |..      .|.  .|        . | ..   |.|| .|  ..       . ..  ..  .||   .|..||. . .   | . 
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI---HECF
CNH ZC404.9.AA CNH 483-804 28 1.7e-133 450.73 SMART 1-375 (375) Show / Hide 
Range on Protein: 483-804
Range on HMM: 1-375/375
Sequence Identity: 28% (106 aa)

CAASWVHPLTGAH----LLLFGTEQGIYSFDTNCMP----DGNLSKIHHRR---CSWMFVYADRLTAIQGNTPYVYRHDLVALTQKNLTLKMSKN--LNK
|...|.||.|...    .||.|||.|||....||..    .|....|||||   |.|.......|..|.|..|..|.|.||.|.||..|..|...   ..
CTMKWCHPITCDQLWGKWLLVGTEHGIYCLNINCQQNQDHEGTPEHIHHRRCVTCMWVYEENNCLMMISGKKPHLYSHPLVWLFQKYRTQGMTPHIQDHM

IPEKYVPKRLAITVRMPETRG-ALQCTVKRGQGAQANSLFLCCAVRKTVHLF-QWYNPMNQFVLVR------------SEPIREDIRFPIRPFALINSRT
.....||.....|...|.|.| ...|.|| ..|......|||.|....|... ||||||..|....            ....|....||...|.......
CNHHLVPRKNVWTTKIPDTKGNCHHCCVK-CNGKRTGIIFLCHAMQHSVQIYNQWYNPMHKFMCWKSSNNILNNEIEMFKHFRFPEIFPVPVFVCFHHDS

SDFPELCIGVGQ----MSGSNEYQFNMINFC-------SSTNNSELSGDLNSSYGSLADD--EMLEVGSMHQIDR---DTLCFSFRNKVVLTDLQG--FE
...|..|||...    |.|....|......|       |..|....|........|...|  ....|....|.|.   |.......|..|.....|  ..
FERPWICIGCDKPVGGMYGFHMVQHHQHCHCNSFNMHESTVNMNDHSLWFMNQQTSHQQDTCKPHQVHQVQQSDGGQRDMYLLCYDNFGVFVNCYGSEWR

RPKPSIFTFNFHIEYLHVVDGTILAFHANGVQGRDLKSNLN-TQDLCDV----SRLYRVIG----DDRVIILRSQP
|....|....|..||.......|.||..||.|.|..|.. . ||...|.    .| .|...    .||.|...|||
RWRNPILHWEFMPEYFAYHYPYIMAFWDNGIQIRHIKTGEWNTQCIMDRQYIKCRKFRLLCTCECRDRKIFYCSQP
CNH ZC404.9.AA CNH 488-794 19 1.6e-77 268.61 Pfam 1-336 (336) Show / Hide 
Range on Protein: 488-794
Range on HMM: 1-336/336
Sequence Identity: 19% (68 aa)

VHPLTGAHLLLFG-TEQGIYSFDT----NCMPDGNLSKIHHRRCSWMFVYA--DRLTAI--QGNTPYVYRHDLVALTQKN-----LTLKMSKNLNKIPEK
|.| |. . ||.| |..|.|  .     .|. .........||.... | .  . |  |   ......|.|.| .| ||.     .. ..... ..| |.
VCPCTWGQWLLVGTTDEGLYVYNIRNTRDCRHWTRICQKFSRRVTQIYVIEEFNILIMISGCDKNKHLYVHPLDWLDQKEQQWHQCHNPKHRCTHRI-ER

YVPKRLAITVRMPETRGALQCTVKRGQGAQANSLFLCCAVRK-----TVHLFQWYNPMNQF-------------VLVRSEPIREDIRFPI-RPFALINSR
..|.. |.....|.|... ....  .. .. |...|||||..     |.....||.||..|              ..|  ..  ... |.  .| .   .
IMPRKFAMWQKLPDTKHCHFFCW--IRNGYCNGRCLCCAVKRSGLHSTIKCYEWYHPMKKFHKQRSFKGNQEWFRKFRE-CFYIPLP-PMTECFSMHWLP

TSDFPELCIGVGQMSGSNEYQFNMINFC--SSTNNSELSGDLNSSY---GSLADDEMLEVGSMHQIDRD-TLCFSFRNKVVLTDLQGFERPK--PSIFTF
 .. | ||.|.        ..| ..|..  ...  ..|  |.....   .  |. |.... .||.|..| ...... . .|....|| .|..  ......
-QEKPKLCVGC-------QKGFHIVNLDGTGQP--WWLH-DPADHSVQQDFMARRENCKPICMHRINDDEEFLLCYDECCVYVNKQGWPRSRKHDWEIMW

NFHIEYLHVVDGTILAFHANGVQGRDLKSN-LN---TQDLCDVSRLYRVIGD
...... . ... .|||| |....|.....      .| ...... ... | 
EGMPQSFACCYPYLLAFHPNFIEIRHVETGSEWDACVQCIPGQNIRFLHSGS