Gene CLA4 (Bakers Yeast)

CLA4

Species: Bakers Yeast
Alias: CLA4
External Links: Saccharomyces Genome Database Link ,
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: PAKA

Sequence

Name Sequence Type Origin Length Description Download
CLA4.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 280 Kinase domain by global Sugen HMM Fasta, JSON
CLA4.AA Protein Refseq_NP 842 Involved in localizing cell growth with respect to the septin ring; Cla4p [Saccharomyces cerevisiae] Fasta, JSON

Protein domain

Protein domains of CLA4.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PH CLA4.AA PH 62-181 18 1.7e-16 62.08 SMART 1-82 (82) Show / Hide 
Range on Protein: 62-181
Range on HMM: 1-82/82
Sequence Identity: 18% (22 aa)

KKKSGWVSYKDDGILSFIWQKRYLMLHDSYVALYKNDKQNDDAILKIPLTSIISVSRTQLKQYCFELVRCSDRNSVSSGSSSSLNVSSDSNSKKSIYIAT
  |.||.. |     .  |.||...|..... .||..    . . .|||... .|..      |||..  .                       ..|...
VIKEGWLYKKS----K-RWKKRWFVLFNDCLYYYKDK----KPKGSIPLSDC-TVRE-P----CFEIHH-DR----------------------TYYFQC

KTESDLHSWLDAIFAKCPLL
..|.....|..|| . .  .
ESEEEMQEWMQAIQKAIHNN
PH CLA4.AA PH 62-179 20 2e-16 61.89 Pfam 1-92 (92) Show / Hide 
Range on Protein: 62-179
Range on HMM: 1-92/92
Sequence Identity: 20% (24 aa)

KKKSGWVSYKDDGILSFIWQKRYLMLHDSYVALYKNDKQNDDAILKIPLTSIISVSRTQL--KQYCFELVRCSDRNSVSSGSSSSLNVSSDSNSKKSIYI
 .|.||.. |     .  |.||...|..... .||.||   .   .||| .. .| ..    ...||...  .                      ...|.
VIKEGWLHKKG---KRKSWKKRWFVLFNNCLYYYKDDK--YRPKGSIPLSDC-QVTKVPDNKRPHCFQIRT-DR---------------------RTYYF

ATKTESDLHSWLDAIFAKCP
....| ....|..|| . | 
QAESEEEMNDWMQAIQSACR
PBD CLA4.AA PBD 183-241 50 2.6e-28 101.16 Pfam 1-60 (60) Show / Hide 
Range on Protein: 183-241
Range on HMM: 1-60/60
Sequence Identity: 50% (30 aa)

GVSSP-TNFTHKVHVGFDPETGSFVGMPTNWEKLLKHSRITGEDWNNNSAAVIQVLQFYQ
..|.| |||.|..|||.|..|| |.|||..|.|||..| |. .....|..||..|.||||
MISTPLTNFKHTMHVGWDGQTGFFTGMPPEWQKLLQSSGISKPEQKHNPQAVFDVVQFYQ
PBD CLA4.AA PBD 184-219 55 5.9e-18 66.89 SMART 1-38 (38) Show / Hide 
Range on Protein: 184-219
Range on HMM: 1-38/38
Sequence Identity: 55% (21 aa)

VSSPT-NFTHKVHVG-FDPETGSFVGMPTNWEKLLKHS
.|.|| ||.|.|||| .|..|| |.|.|..|..||||.
ISTPTGNFKHIVHVGPWDGQTGEFTGLPHQWQHLLKHC
Kinase CLA4.AA PAKA 546-825 58 1.8e-188 632.44 In-house 1-260 (260) Show / Hide 
Range on Protein: 546-825
Range on HMM: 1-260/260
Sequence Identity: 58% (165 aa)

FKVIEKAGQGASGSVYLAERTHIPTESNMIELINNDIDEPHVGDKVAIKQMVLSKQPRKELIVNEILVMKDSRHKNIVNFLEAYLRTDDDLWVVMEFMEG
.|..||.||||||.||.|.......|.|                 |||||| ...||.||||.|||||||...||||||....||  ||.||||||.|||
YKFMEKIGQGASGEVYVATNIKTNQEEN-----------------VAIKQMNMKNQPKKELIINEILVMKECKHKNIVNYIDSYLV-DDELWVVMEYMEG

GSLTDIIENSP-TNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTRARVKITDFGFCARLTDKRSKRATMVGTPYWMAPEVVKQRE
|.|||.|..   ...|   ...| ||||..||..|||.|.|.||.|||||||||.||.....||||||||||.||....||.|||||||||||||.....
GCLTDVITQCCNIQCN---YMDEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRKQ

YDEKIDVWSLGIMTIEMLEGEPPYLNEDPLKALYLIATNGTPKLKHPESLSLEIKRFLSVCLCVDVRYRASTEELLHHGFF
||||.|.||||||.|||.|||||||||.||.|.|||||||.|..|.|...| |...||. ||||||..|||..||||| |.
YDEKVDIWSLGIMAIEMIEGEPPYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase CLA4.AA STE20 546-825 43 2.3e-149 502.5 In-house 1-288 (288) Show / Hide 
Range on Protein: 546-825
Range on HMM: 1-288/288
Sequence Identity: 43% (134 aa)

FKVIEKAGQGASGSVYLAERTHIPTE--SNMIELINNDIDEPHVGDKVAIKQMVLSKQ----PRKELIVNEILVMKDSRHKNIVNFLEAYLRT---DDDL
.. .|| |||..|.||.|  .|.||   .|               ..||||.| |.|.    ...|.|..||..||...|.|||.....||.    ||.|
YELLEKIGQGSYGKVYKA--YHKPTGEYCN---------------QRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDEL

WVVMEFMEGGSLTDIIENS-PTNDNSHS--PLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTRARVKITDFGFCARLTD-----KRSKRATM
|.|||...|||||||.... ... | |.  |..|.||||| ||..|||..|| .||||||||.||.||.....||..|||.|| ||.     ...|| |.
WIVMEYCGGGSLTDIMKHCMKCGKN-HKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTF

VGTPYWMAPEVVKQ-----REYDEKIDVWSLGIMTIEMLEGEPPYLNEDPLKALYLIA--TNGTPKLKH--PESLSLEIKRFLSVCLCVDVRYRASTEEL
|||||||||||...      .||.| |.|||||..|||.||||||... |..|...|.  .|..|.||.  |.. | | . |...||..|.  |.....|
VGTPYWMAPEVIQCMEGPDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQL

LHHGFF
|.| |.
LKHPFI
Kinase CLA4.AA STE 546-825 32 4.3e-122 411.9 In-house 1-359 (359) Show / Hide 
Range on Protein: 546-825
Range on HMM: 1-359/359
Sequence Identity: 32% (120 aa)

FKVIEKAGQGASGSVYLAERT------HIPTESNMIELINNDIDEPHVGDKVAIKQMVLSKQ-----------------PRKELIVNEILVMKDSR--HK
.. ||| |.||.|.||.| .       .   ..|          . . |. .||||| |...                   .. | .|| .||...  |.
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVEN----------NGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHP

NIVNFLEAYLRT------DDDLWVVMEFMEGGSLTDIIE-NSPTNDNSH------SPLTEPQIAYIVRETCQG-LKFLHDKHIIHRDIKSDNVLLDTRAR
|||... .|..       ||.||..||.|.||||.|||. .  .... .      ... |.|||||.|....| |..||..||||||||..|.||     
NIVKYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----

VKITDFGFCARLTDK----------------RSKRATMVGTPYWMAPEVVKQ------REYDEKIDVWSLGIMTIEMLEGEPPYLNEDPLKALYLIATN-
||..|||.|..|||.                 .|| |.|||| ||||||..|       .||.| |.||||.. |||..|.||. .. |..|...|..| 
VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNY

--------------GTPKLKH-----------------PESLSLEIKRFLSVCLCVDVRYRASTEELLH--HGFF
              . |.|..                 |...| | | |.. ||  | . |.....||.  | |.
HMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase CLA4.AA PAKB 584-825 48 4.3e-100 338.82 In-house 20-252 (252) Show / Hide 
Range on Protein: 584-825
Range on HMM: 20-252/252
Sequence Identity: 48% (117 aa)

EPHVGDKVAIKQMVLSKQPRKELIVNEILVMKDSRHKNIVNFLEAYLRTDDDLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKF
| | |  ||.|.| | || | ||  ||. .| | .|.|||.. . ||  .| |||||||||||.||||.        .|. ..|.|||.. |   | | .
EKHTGRQVAVKKMDLRKQQRRELLFNEVVIMRDYQHPNIVEMYSSYL-VGDELWVVMEFMEGGALTDIV--------THTRMNEEQIATVCRQVLQALAY

LHDKHIIHRDIKSDNVLLDTRARVKITDFGFCARLTDKRSKRATMVGTPYWMAPEVVKQREYDEKIDVWSLGIMTIEMLEGEPPYLNEDPLKALYLIATN
|| . .|||||||| .||    ||| .|||||| .     ||  .|||||||||||.    |. ..|.|||||| ||| .||||| || ||.|.  |  .
LHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPKRKSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMVDGEPPYFNEPPLQAMKRIRDM

GTPKLKHPESLSLEIKRFLSVCLCVDVRYRASTEELLHHGFF
  |.||     | . . ||. .|  |.  |.. .|||.| |.
HPPRLKNHHKVSPRLREFLDRMLVRDPNQRWTAQELLRHPFL
Kinase CLA4.AA S_TKc 546-825 29 8.4e-90 305.57 SMART 1-231 (231) Show / Hide 
Range on Protein: 546-825
Range on HMM: 1-231/231
Sequence Identity: 29% (86 aa)

FKVIEKAGQGASGSVYLAERTHIPTESNMIELINNDIDEPHVGDKVAIKQMVLSKQPRKELIVNEILVMKDSRHKNIVNFLEAYLRTDDDLWVVMEFMEG
.....| |.|| |.||..  ..                    | .||||..        | | .|| ..|  .|.|||......    |.|..|||...|
YEILRKIGKGAFGKVYKCRHKK-------------------TGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDG

--GSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTRARVKITDFGFCARLTDKRSKRATMVGTPYWMAPEVVKQR
  |.| |.|.. ... . ..|..| .........|..|...|...|||||.| .|.|||.  ..||.|||....|        |..|||..|||||.   
DLGDLFDYIKKRGRHGL-RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---

EYDE-KIDVWSLGIMTIEMLEGEPPYLNEDPLKALYLIATNGTPKLKHPESLSLEIKRFLSVCLCVDVRYRASTEELLH-------HGFF
 |.  |.|.||.|.. .||| |.||.   .. . . .|              | | | |.. ||..| . | .  |.|.       | .|
GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CLA4.AA Pkinase 546-825 25 1.4e-86 298.74 Pfam 1-293 (293) Show / Hide 
Range on Protein: 546-825
Range on HMM: 1-293/293
Sequence Identity: 25% (83 aa)

FKVIEKAGQGASGSVYLAERTHIPTESNMIELINNDIDEPHVGDKVAIKQMVLSKQPRKELIVN----EILVMKDSRHKNIVNFLEAYLRTDDDLWVVME
.....| |.|..|.||.. .   .                    .||.|.. ....  .... .    || .||  .|.||| ..... . .|....|||
YHIGRKIGSGSFGCVYKCHHKGTGK-------------------IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVME

FMEGG----SLTDIIENSPTNDNSHSPL--TEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTRARV----KITDFGFCARL-TDKRSKRATMVG
..|||    .| |.|.       .| ..  .| ..  .......||...|.. |||||.|..|.|.| .  .    ||.|||... . . . |   | .|
YCEGGLYVMDLFDYIST-----WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCG

TPYWMAPEVVK-QREYDEKIDVWSLGIMTIEMLEGEPPYLNE----DPLKALYLIATNGTPKLKHPESLS---------------------LEIKRFLSV
||..|||||.. ...|. |.|.||.|.. .||| |.||. ..    . .  ...|. .. |.|. ... .                      | | |.. 
TPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKW

CLCVDVRYRASTEELLHHGFF
|||.|   | . |..|.| .|
CLCKDPKKRPTAEQILQHPWF
Kinase CLA4.AA YSK 605-825 42 5.6e-82 246.56 In-house 42-257 (257) Show / Hide 
Range on Protein: 605-825
Range on HMM: 42-257/257
Sequence Identity: 42% (95 aa)

ELIVNEILVMKDSRHKNIVNFLEAYLRTDDDLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTR
|.|  || .  .    .| ... .||. |  ||..||.  |||. | .  .  .     .. |..|| | ||  .||..||    ||||||. ||||   
EDIQQEIQFLSQCDSPYITKYYGSYLK-DTKLWIIMEYCGGGSCLDLMKPKYVG-----QFDEKYIAIILREILKGLDYLHSERKIHRDIKAANVLLSEH

ARVKITDFGFCARLTDKRSKRATMVGTPYWMAPEVVKQ--REYDEKIDVWSLGIMTIEMLEGEPPYLNEDPLKALYLIATNGTPKLKHPESLSLEIKRFL
  ||. |||  ...||   || |.|||||||||||..|   .||.| |.||||| ..||. |||||   .|.... ||  |  |||.  .| |   | | 
GDVKLCDFGVAGQITDTQIKRNTFVGTPYWMAPEVICQEVSYYDFKADIWSLGITAYEMAKGEPPYCDYHPMRVMFLIPKNNPPKLEG-RSYSKMFKEFV

SVCLCVDVRYRASTEELLHHGFF
 .||  | . | | .||| | | 
ECCLNKDPEQRPSAKELLKHKFI
Kinase CLA4.AA MST 607-825 42 7.4e-75 237.35 In-house 41-254 (254) Show / Hide 
Range on Protein: 607-825
Range on HMM: 41-254/254
Sequence Identity: 42% (93 aa)

IVNEILVMKDSRHKNIVNFLEAYL-RTDDDLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTRA
| .||  |..   |.|| .   |.   . ..| |||. ..||. ||.           .|.| ||| | . | |||. ||| ..||||||. | ||... 
IIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMK------ITQRTLNEQQIACILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEG

RVKITDFGFCARLTDKRSKRATMVGTPYWMAPEVVKQREYDEKIDVWSLGIMTIEMLEGEPPYLNEDPLKALYLIATNGTPKLKHPESLSLEIKRFLSVC
  |  |||  . |||   || | .||||||||||  .  || | | |||||  ||| ||.||| .  |  |. .| ..  |..| ||  | |  .|.. |
ECKLADFGVSGQLTDTMAKRNTVIGTPYWMAPEVIQEIKYDCKADIWSLGITAIEMAEGMPPYSDIHPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKC

LCVDVRYRASTEELLHHGFF
|  .   |.. |.|| | |.
LQKNPEQRWTAEQLLQHPFI
Kinase CLA4.AA MSN 588-825 40 8.3e-70 229.62 In-house 24-265 (265) Show / Hide 
Range on Protein: 588-825
Range on HMM: 24-265/265
Sequence Identity: 40% (101 aa)

GDKVAIKQMVLSKQPRKELIVNEILVMKDSRHKNIVNFLEAYLR-----TDDDLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLK
|  .||| | . .    |.  .  .. | | |.||. .  |...      |. ||.||||   ||.||.. .  | ..|   | |  |||| ||  .|| 
GQLAAIKVMDVREDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGHDHQLWMVMEFCGAGSVTDLVKM--TKGQS---LKEDWIAYICREILRGLA

FLHDKHIIHRDIKSDNVLLDTRARVKITDFGFCARLTDKRSKRATMVGTPYWMAPEVVK-----QREYDEKIDVWSLGIMTIEMLEGEPPYLNEDPLKAL
.|| ...||||||  ||||   | ||. |||  | |     .| | .||||||||||..     .. || . |.||.||  ||| ||.||  .  |..||
HLHQHKVIHRDIKGQNVLLTHNAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSVGITAIEMAEGQPPLCDMHPMRAL

YLIATNGTPKLKHPESLSLEIKRFLSVCLCVDVRYRASTEELLHHGFF
.||  |  ||||  .  |   . |.  ||  .   | .||..|.|.| 
FLIPRNPPPKLK-SKKWSKKFHNFMEKCLIKNYHQRPYTEQMLKHPFI
Kinase CLA4.AA KHS 586-825 39 1.2e-63 212.95 In-house 22-258 (258) Show / Hide 
Range on Protein: 586-825
Range on HMM: 22-258/258
Sequence Identity: 39% (96 aa)

HVGDKVAIKQMVLSKQPRKELIVNEILVMKDSRHKNIVNFLEAYLRTDDDLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLH
. .. .|.| . .  .   ..|  ||..||| || ||| .  .|||  | ||..||.  |||| || .          ||.| ||||. ||| |||..||
QSDELAAVKVIKMEPGDDFAVIQQEIMMMKDCRHPNIVAYFGSYLRR-DKLWICMEYCGGGSLQDIYHVT-------GPLSELQIAYVCRETLQGLHYLH

DKHIIHRDIKSDNVLLDTRARVKITDFGFCARLTDKRSKRATMVGTPYWMAPEVV---KQREYDEKIDVWSLGIMTIEMLEGEPPYLNEDPLKALYLIAT
 .  .|||||  |.||  .  ||. |||  |..|   .||   .||||||||||    ..  |..  |.|..||  ||. |  ||  .  |..||.|.. 
SMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWAVGITAIELAELQPPMFDLHPMRALFLMTK

NG--TPKLKHPESLSLEIKRFLSVCLCVDVRYRASTEELLHHGFF
 .   ||||  .  |     |. ..|  . . | . | ||.| |.
SNFQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase CLA4.AA STE11 591-825 31 1.6e-63 217.34 In-house 27-303 (303) Show / Hide 
Range on Protein: 591-825
Range on HMM: 27-303/303
Sequence Identity: 31% (89 aa)

VAIKQMVLSKQP----------RK----ELIVNEILVMKDSRHKNIVNFLEAYLR--TDDDLWVVMEFMEGGSLTDIIE-NSPTNDNSHSP--LTEPQIA
.|.||. . ..           ..    ..|  || .||  .||||| .. . |.   .| . . ||...|||| .... .         |  ..|. | 
MAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCPGGSLSSMLRHKW-------GPMKFDEMVIR

YIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTRAR-VKITDFGFCARLTDKRSKRAT----------MVGTPY--------WMAPEVVKQRE---YDEKI
. ..  ..||..||...||||||| .|.|||.    .|..||| . ||    .. ..          | ||||        ||||||.||     |. | 
KYTKQILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNSMMGTPMWMAPEVIKQEGRDGYGRKA

DVWSLGIMTIEMLEGEPPYLNED--PLKALYLIATNGTPKLKHPESLS------LEIKRFLSVCLCVDVRYRASTEELLHHGFF
|.||||   |||. | ||. | |  .  |.. |... .|    ||..|       | ..||. |.  |  .|..  .|| | |.
DIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTANQLLQHPFI
Kinase CLA4.AA Ciliate-E2 546-825 22 2.6e-63 216.16 In-house 1-365 (365) Show / Hide 
Range on Protein: 546-825
Range on HMM: 1-365/365
Sequence Identity: 22% (90 aa)

FKVIEKAGQGASGSVYLAERTHIPTESN------------MIELINNDIDEPHVGDKVAIKQ---MVLSKQPRKEL-IVNEIL--------------VMK
.|.|.| |||. ||||....   . ...            | .            .||.||.    ...|.  ...  .. |.              ...
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQM-Q------------EKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILE

DSRHKNIVNFLEAYLR-TDDDLWVVMEFMEGGSLTDIIENSPTNDNSHSP----LTEPQIAYIVRETCQ---------------GLKFLHDKH-IIHRDI
   |.||... |..   .|. .  |||. .||.| |.|.|.... |.. .    .|| .|.|| .. .|               .|..|| |. ||||||
QLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDI

KSDNVLLDTRARVKITDFGFCARLTDKRSKR-------------------------------ATMVGTPYWMAPEVVKQRE---------YDEKIDVWSL
| .|.|.     .||.|||.. ...|.. .|                                | .|||. ||||...  .         ||.|.|.|||
KPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSL

GIMTIEMLEGEPPYLNEDPLKALYLIATNGTPKLK----------------HPESLSLEIKRFLSV----CLCVDVRYRAS-TEELLHHGFF
|..  ||| |.||.         . .  ..  ..                  ....|.| | ...     .|..|   | .  |..| | .|
GVILYEMLFGKPPF---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase CLA4.AA Pkinase_Tyr 546-713 25 8e-28 94.86 Pfam 1-156 (270) Show / Hide 
Range on Protein: 546-713
Range on HMM: 1-156/270
Sequence Identity: 25% (44 aa)

FKVIEKAGQGASGSVYLAERTHIPTESNMIELINNDIDEPHVGDKVAIKQMVLSKQPR---KELIVNEILVMKDS-RHKNIVNFLEAYLRTDDD--LWVV
 . ..| |.|| |.||... .                |.   . .||.| .  .  ..   .|   .|. .||   .|.|||... . .. ..   ...|
ITFGKKLGEGAFGEVYKGTWKG---------------DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIV

MEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTRARVKITDFG
||.|..|.| |   .     ..  ||| ...  . .. ..|. .|..|..||||.   |.|..    |||.|||
MEYMPHGDLLDYLRKHR---EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase CLA4.AA TyrKc 546-825 21 1.4e-27 98.85 SMART 1-280 (280) Show / Hide 
Range on Protein: 546-825
Range on HMM: 1-280/280
Sequence Identity: 21% (69 aa)

FKVIEKAGQGASGSVYLAERTHIPTESNMIELINNDIDEPHVGDKVAIKQMVLSKQPRKELIVNEILVMKDS--RHKNIVNFLEAYLRTD-------DDL
 . ..| | || | ||... .                       .||.| .  ..   .| . .|. .|.    .|.|||... .. ...       . |
ITLGKKLGEGAFGEVYKGTWK----------------------IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLY-GVCTQQGRNFMYIEPL

WVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTRARVKITDFGFCARLTDK----RSKRATMV---
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MIVMEYMPHGDLKDYLRKHRPK------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEH

-GTP-----YWMAPEVVKQREYDEKIDVWSLGIMTIEMLE-GEPPYLN-----EDPLKALYLIATNGTPKLKHPES--------LSLEIKRFLSVCLCVD
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KGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGY--RMPQPPNDYPMSFVCCPDEMYQIMKQCWHED

VRYRASTEELLHHGFF
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PEDRPTFSEI--HECF
Kinase CLA4.AA Pkinase_Tyr 734-768 43 2.8e-07 25.26 Pfam 180-216 (270) Show / Hide 
Range on Protein: 734-768
Range on HMM: 180-216/270
Sequence Identity: 43% (16 aa)

WMAPEVVKQREYDEKIDVWSLGIMTIEMLE-GEPP-Y
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WMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTY
Kinase CLA4.AA MST 546-563 61 0.000668 8.2 In-house 1-18 (254) Show / Hide 
Range on Protein: 546-563
Range on HMM: 1-18/254
Sequence Identity: 61% (11 aa)

FKVIEKAGQGASGSVYLA
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FDIVEKLGQGSYGSVYKA
Kinase CLA4.AA KHS 546-567 27 0.123379 1.12 In-house 1-22 (258) Show / Hide 
Range on Protein: 546-567
Range on HMM: 1-22/258
Sequence Identity: 27% (6 aa)

FKVIEKAGQGASGSVYLAERTH
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YELLQRVGSGTYGDVYKARDIQ