Gene KNS1 (Bakers Yeast)

KNS1

Species: Bakers Yeast
Alias: KNS1
External Links: Saccharomyces Genome Database Link ,
Annotation:

Classification

Group: CMGC
Family: CLK

Sequence

Name Sequence Type Origin Length Description Download
KNS1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 289 Kinase domain by global Sugen HMM Fasta, JSON
KNS1.AA Protein Refseq_NP 737 protein kinase homolog; Kns1p [Saccharomyces cerevisiae] Fasta, JSON

Protein domain

Protein domains of KNS1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase KNS1.AA CLK 313-577 43 2.7e-183 555.13 In-house 1-289 (350) Show / Hide 
Range on Protein: 313-577
Range on HMM: 1-289/350
Sequence Identity: 43% (125 aa)

FVVKDLLGQGTFGKVLKCIDNKYEPNYVAVKVIRAVDRYREAAKTELR-ILQTILNN-DPQGQFQ--CLLLRECFDY-KNHICLVTDLYGRSIYDFMCSN
..... ||.||||||..|.|.|....|||.|.||.|..|||||..|.. |...| .. ||.....  |......||| ..|||.|..|||.||||||.||
YEIVCTLGEGTFGKVVECWDHKNGKKYVALKIIRNVEKYREAAWVEINQIMKKINEKHDPNNKYWEHCWKMNDWFDYGHGHICIVFELYGLSIYDFMKSN

G------IARFPGSHIQAIARQLIRSVCFLHDLGIIHTDLKPENILICDE--THIAQKLPLKTVQSLSKRRREASKGKRKILKNPEIKIIDFGSAI---F
.      ....|..||...|.||...|.||||....|||||||||...|.  ||..............|.. ..........||..|..||||||.   |
NSKMPNKYIPYPIDHIRHMAYQLCEAVKFLHDMKLTHTDLKPENICFVDSRFTHFDCTFKYNHKKKINKKS-NNCVCHYWHVKNTHICVIDFGSATKIRF

HYEYHPPVISTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVIGESLYPIHENLEHMAMMQRINGTPFP-----TDI----IDKMFYKSK
..|.|....|||||||||..||||||.|||.|||.|.|.||..|..|...|.|.||.|||.||.|.|.|     ...    ..| ||. .
DHEHHSTIVSTRHYRAPEVILGLGWSQPCDVWSIGCILFELYTGFTLFQTHDNREHLAMMERIMGMPIPQWMIQRTRRFKVKQKYFYHNR
Kinase KNS1.AA CMGC 313-563 20 6e-74 242.13 In-house 1-373 (513) Show / Hide 
Range on Protein: 313-563
Range on HMM: 1-373/513
Sequence Identity: 20% (81 aa)

FVVKDLLGQGTFGKVLKCID-------------NKYEPNYVAVKVIRAVDRYREAAK-------------TELRILQTILNN---------DPQGQFQ--
. . . .|.||.|.| ||.|             ..   ..||.| |. .  | | ||              |..||. . .|         ||...    
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

CLLLRECFDYKN-----------------HICLVTDLYGRSIYDFMCSNG--------------------------IARFPGSHIQAIARQLIRSVC--F
.. |...| .||                 |..||... . . |... .|                           |  |.  ||. ...|..|..   .
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLKY

LHDLG--IIHTDLKPENILICDETHI--------AQKLPLKTVQSLSKRRREASKGKRKILKNPEIKIIDFGSAIFHYEY--------------------
.|  .  |||.|||||||||....                         . . ..     .|| ..||.|||.| .  ..                    
CHSHWGNIIHRDLKPENILINHNCELITRMMWKSE--------------D-W-NPC----QKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDK

----HPPVISTRHYRAPEIVLGLG----------WSFPCDIWSIACVLVELVIG--------ESLYPIHEN-----------LEHMAMMQRINGTP
    . . ..||.|||||| || .          .. |.|.||..|.. |.. |        . | | | .           ....... .. |||
PNRPYTHYVVTRWYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTP
Kinase KNS1.AA S_TKc 313-720 18 1.2e-71 245.27 SMART 1-231 (231) Show / Hide 
Range on Protein: 313-720
Range on HMM: 1-231/231
Sequence Identity: 18% (78 aa)

FVVKDLLGQGTFGKVLKCIDNKYEPNYVAVKVIRAVDRYREAAKTELRILQTILNNDPQGQFQCLLLRECFDYKNHICLVTDLYGR---SIYDFMCSNGI
. . ...|.|.|||| ||...|    .||.|.|.      | .. |..||.        .      | ..|.  .|...|... .    . .|.....| 
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK------EHIRREIQILKK-------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

AR----FPGSHIQAIARQLIRSVCFLHDLGIIHTDLKPENILICDETHIAQKLPLKTVQSLSKRRREASKGKRKILKNPEIKIIDFGSAIFHYEYHPPVI
 .    ||  |.. ...|... . ..|..|||| ||||||||...                                  .|||.|||.| .       ..
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----------------------------------HIKICDFGLARQL----TTFC

STRHYRAPEIVLGLGWSF-PCDIWSIACVLVELVIGESLYPIHENLEHMAMMQRINGTPFPTDIIDKMFYKSKHKLGNSPSDLNSTVIKHFDRKTLSLQW
 |..|.|||..   |... .||.||. |.| |.. |. ..|     ....|...|                                             
GTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP-----QMQMMFKKIG--------------------------------------------

PEKNKRGDTITTEKSMKRVLQSCDRLDIYISKVLKQDYGDSLSINWNLPPEKNWSLINSKLAWKRQTHSSSSSTTDELDKETFLFWYWFIDLLRKMFEFD
                                                                                        ..|..||....|
-------------------------------------------------------------------------------------SPEAKDFIRKCLQKD

PTKRITAKDALD-------HEWF
|.||.|| .||        |.||
PEKRPTA-EALQDEWDIKCHPWF
Kinase KNS1.AA Pkinase 313-568 25 1.2e-50 179.42 Pfam 1-239 (293) Show / Hide 
Range on Protein: 313-568
Range on HMM: 1-239/293
Sequence Identity: 25% (70 aa)

FVVKDLLGQGTFGKVLKCIDNKYEPNYVAVKVIRAVDRYREAAKT-----ELRILQTILNNDPQGQFQCLLLRECFDYKNHICLVTDLYGR-----SIYD
....  .|.|.||.| ||.. ...   ||||.|. ...  .  .|     |..|.. . |      .  . |...| .|.||..|... .      . .|
YHIGRKIGSGSFGCVYKCHHKGTGK-IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-N----HPN-IVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFD

FMC---SNGIARFPGSHIQAIARQLIRSVCFLHDLGIIHTDLKPENILICDETHIAQKLPLKTVQSLSKRRREASKGKRKILKNPEIKIIDFGSA----I
..    ....  |.  ... ...|..| . ..|. |||| ||||||||| .. ||.                              .||.|||.|    .
YISTWRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA----------------------------CVKICDFGLAKQFDY

FHYEYHPPVISTRHYRAPEIVL-GLGWSFPCDIWSIACVLVELVIGESLYPIH----ENLEHMAMMQRINGTPFPTDI
 ...    .  |..|.|||... | ... ..|.||. |.| |.. |. ..| |    . ...|.|..|| |.|.. |.
-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDW
Kinase KNS1.AA DYRK 313-450 32 3.4e-43 149.84 In-house 1-139 (320) Show / Hide 
Range on Protein: 313-450
Range on HMM: 1-139/320
Sequence Identity: 32% (46 aa)

FVVKDLLGQGTFGKVLKCIDNKYEPNYVAVKVIRAVDRYREAAKTELRILQTILNNDPQGQFQCLLLRECFDYKNHICLVTDLYGRSIYDFMCSNGIARF
. . . .|.|.||.| || |.     .||.|.||   |.   |..|..||. . ..||. .. |. . ..| ..|| |.|..|.  . |.|.. |.   |
YEILEYIGKGSFGQVVKCWDH-KTNEMVAIKIIRNNKRFHRQAQIEIKILEYLNQQDPDDKYHCVHMYDYFYHRNHLCIVFELLSMNLYEFLKNNHFQGF

-PGSHIQAIARQLIRSVCFLHDL-GIIHTDLKPENILICD
 . .... .|.|.  . .||| .  ||| |||||||....
FSLNLVRKFAQQILTCLKFLHKNENIIHCDLKPENIMLKQ
Kinase KNS1.AA DYRK2 313-447 34 7.6e-39 123.73 In-house 1-134 (318) Show / Hide 
Range on Protein: 313-447
Range on HMM: 1-134/318
Sequence Identity: 34% (46 aa)

FVVKDLLGQGTFGKVLKCIDNKYEPNYVAVKVIRAVDRYREAAKTELRILQTILNNDPQGQFQCLLLRECFDYKNHICLVTDLYGRSIYDFMCSNGIARF
. ..  .|.| || |.|| | |..  .||.|.||   |. . | .|.|||. |  .|..... |  ... | . ||.|....|.. ..|.... |    |
YEILEVIGKGSFGQVVKCYDHKTK-QHVAIKMIRNKKRFHNQAYEEIRILHHIRRQDKDNTMNCVHMLDYFYFRNHHCITFELLSMNLYEYIKKNHFQGF

PGSHIQAIARQLIRSVCFLHDLGIIHTDLKPENIL
  . . . |.... .  |||   ||| ||||||||
SLQLVRRFAHSILQCLRFLHKNNIIHCDLKPENIL
Kinase KNS1.AA HIPK 313-452 35 1.5e-31 96.25 In-house 1-138 (329) Show / Hide 
Range on Protein: 313-452
Range on HMM: 1-138/329
Sequence Identity: 35% (49 aa)

FVVKDLLGQGTFGKVLKCIDNKYEPNYVAVKVIRAVDRYREAAKTELRILQTILNNDPQGQFQCLLLRECFDYKNHICLVTDLYGRSIYDFMCSNGIARF
. | ..||.||||.| ||   .     ||.|...    |    . |..||. . . ... ... .   |||. |||.||| ..    .|||.  |  .  
YEVLEFLGRGTFGQVVKCW-KRGTNEMVAIKILKNHPYYARQGQIEVSILHCLSQENAD-EYHFVRAYECFHHKNHTCLVFEMLEQNLYDFQKQNKFMPL

PGSHIQAIARQLIRSVCFLHDLGIIHTDLKPENILICDET
|  || .|  | ..    | .||.|| |||||||.. |.|
PLKHIRPILQQVLTALMKLKELGLIHADLKPENIMLVDPT
Kinase KNS1.AA Ciliate-E2 313-551 17 1.1e-26 88.59 In-house 1-302 (365) Show / Hide 
Range on Protein: 313-551
Range on HMM: 1-302/365
Sequence Identity: 17% (60 aa)

FVVKDLLGQGTFGKVLKC--IDNKYEPNYV--------------AVKVIRAVDRYREAAKTELRILQTILNNDPQGQFQ---------------CLLLRE
. .  ..|||.||.| ||  . .... ...              . . | |. ....  . ..   . |..    ..                  . . |
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFY-KKINEKNILEQLNHPNIIKMYE

CFD--YKNHICLVTDLY-GRSIYDFMCSNGIARFPG---------SHIQAIARQLIR---------------SVCFLHDLG-IIHTDLKPENILICDETH
||    .|.| ||.... | . .|.. .| . |.            .|. | .|...                . .||  . ||| |.||||||.     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

IAQKLPLKTVQSLSKRRREASKGKRKILKNPEIKIIDFGSAIF-------------HYEYHPPV----------------------ISTRHYRAPEIVLG
                                ||||||| . .             ...|                          . | .| ||||. |
--------------------------------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNG

LG---------WSFPCDIWSIACVLVELVIGESLYPIHENLE
 .         ... |||||. ..| |.. |.  . . ....
KKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF-QQQIKQ
Kinase KNS1.AA STE 313-563 15 1.8e-26 90.53 In-house 1-300 (359) Show / Hide 
Range on Protein: 313-563
Range on HMM: 1-300/359
Sequence Identity: 15% (52 aa)

FVVKDLLGQGTFGKVLKCIDNKYEPNY--------------VAVKVIRAVD------------------RYREAAKTELRILQTILNNDPQGQFQC---L
.   . .|.|.||.| |....|  ...              .|.|...  .                    ..  . |..|..   .        .    
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNH------M-HPNIV

LLRECFDYK-------NHICLVTDLYG-RSIYDFMCSNGIA------------RFPGSHIQAIARQLIRS-VCFLHDLGIIHTDLKPENILICDETHIAQ
    |. ..       ......  . .  |. |.. ....             ||| | | .|.||...    .||...||| |.|| |||.        
KYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL--------

KLPLKTVQSLSKRRREASKGKRKILKNPEIKIIDFGSAIFHYE------------------YHP-PVISTRHYRAPEIVLG------LGWSFPCDIWSIA
                             .|..||| .    .                   .   .. |  . |||....       | .. |||||. 
-----------------------------VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLG

CVLVELVIGESLY---PIHENLEHMAMMQRIN----------GTP
|...|.. |.  .   . .... ........           |.|
CTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPP
Kinase KNS1.AA CAMK 318-534 16 1.2e-25 78.99 In-house 1-324 (425) Show / Hide 
Range on Protein: 318-534
Range on HMM: 1-324/425
Sequence Identity: 16% (59 aa)

LLGQGTFGKVLKCIDNKYE-----------PNYVAVKVIRAV-----------------------------DRYREAAKTELRILQTI------LNNDPQ
 ||.|.|||| .||. .             .  ||.|.|                                .. |.  . |..|....      |.    
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

GQFQCLLL--------RECF-DYKN-------HICLVT---DLYGR-----SIYDFMCSNGI-------------ARFPGSHIQAIARQLIRSVCFLHDL
 ..             .. .   ..       |...|.   ..         ..|. ...|               ||. .  . . ||..  | ..|..
IKLYEVYEDPHYFKNTND-YET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSH

GIIHTDLKPENILICDETHIAQKLPLKTVQSLSKRRREASKGKRKILKNPE--------IKIIDFGSA--IFHYEYHPP---------------------
.|.| ||||||||..|     .. . .                       |        ||||||| |  ... |                         
NIVHRDLKPENILLDDNNDDSDP-V-E-HD--------------------EIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQK

---VISTRHYRA-PEIVLG--------------LGWSFPCDIWSIACVL
   .  | .| | ||...|               . ...||.||. ..|
MKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVIL
Kinase KNS1.AA DYRK1 313-449 32 1.2e-24 83.14 In-house 1-138 (321) Show / Hide 
Range on Protein: 313-449
Range on HMM: 1-138/321
Sequence Identity: 32% (45 aa)

FVVKDLLGQGTFGKVLKCIDNKYEPNYVAVKVIRAVDRYREAAKTELRILQTILNNDPQGQFQCLLLRECFDYKNHICLVTDLYGRSIYDFMCSNGIARF
. .  |.|.| ||.| |  | . |  |||.|.|.    . . |. |.|.|  . ..|.. ... . |.. | ..||.|||..|    .|| .        
YEIDSLIGKGSFGQVVKAYD-HQEQEYVAIKIIKNKKPFYNQAQIEIRLLELMNKHDKEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGV

PGSHIQAIARQLIRSVCFLH--DLGIIHTDLKPENILIC
    .. .|.|..... |.   .| ||| ||||||||.|
SLNLTRKFAQQMCTALLFMSTPELDIIHCDLKPENILLC
Kinase KNS1.AA YAK 313-449 37 3.1e-22 72.02 In-house 1-140 (347) Show / Hide 
Range on Protein: 313-449
Range on HMM: 1-140/347
Sequence Identity: 37% (53 aa)

FVVKDLLGQGTFGKVLKCIDNKYEPNYVAVKVIRAVDRYREAAKTELRILQTILNN--DPQGQF---QCLLLRECFDYKNHICLVTDLYGRSIYDFMCSN
..| | ||||||| | ||  .  .   .|||||     |   ||.| .||. .||   || .       | .   | .||| |||  .   . |...  |
YIVLDMLGQGTFGQVVKCQNCDTN-ELFAVKVIKNRQAYFQQAKNEIQILR-VLNQQHDPNNKNYQKHILRMYDFFVHKNHFCLVFEMLSNNLYEYLKQN

GIARFPGSHIQAIARQLIRSVCFLHDLGIIHTDLKPENILIC
    |  . |.    |   . | | .  ||| |||||||. |
KFCGFSFQLIRQWTKQILDGMCVLENKQIIHCDLKPENIMLC
Kinase KNS1.AA CLK 693-720 64 2.4e-19 54.01 In-house 323-350 (350) Show / Hide 
Range on Protein: 693-720
Range on HMM: 323-350/350
Sequence Identity: 64% (18 aa)

FIDLLRKMFEFDPTKRITAKDALDHEWF
..||.|||.|.||.||||.||||.|..|
LFDLIRKMLEYDPSKRITCKDALQHPFF
Kinase KNS1.AA DYRK2 486-574 38 3.6e-17 52.08 In-house 143-231 (318) Show / Hide 
Range on Protein: 486-574
Range on HMM: 143-231/318
Sequence Identity: 38% (35 aa)

IKIIDFGSAIFHYEYHPPV-ISTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVIGESLYPIHENLEHMAMMQRINGTPFPTDIIDKMFY
||.|||||  | ..|.  . | .| |||||. ||.  . . |.||  |...||..|  | |     . .|.|. . | | | ...|. ||
IKVIDFGSSCFEHQYRIYTYIQSRFYRAPEVILGGKYGMAIDMWSFGCIMAELYTGYPLFPGENENDQFACMMEVLGMP-PKKFFDTWFY
Kinase KNS1.AA DYRK 482-545 42 8e-17 59.62 In-house 142-205 (320) Show / Hide 
Range on Protein: 482-545
Range on HMM: 142-205/320
Sequence Identity: 42% (27 aa)

KNPEIKIIDFGSAIFHYEYHPPVISTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVIGESLYP
....||.|||||. |  .   . |  |.|||||. ||.  . . |.||  |.|.||..|. |.|
NKSTIKVIDFGSSCFEHQRIYTYIQSRFYRAPEVILGCPYCYAIDMWSLGCILAELFTGWPLFP
Kinase KNS1.AA CMGC 693-720 60 4.5e-16 48.42 In-house 486-513 (513) Show / Hide 
Range on Protein: 693-720
Range on HMM: 486-513/513
Sequence Identity: 60% (17 aa)

FIDLLRKMFEFDPTKRITAKDALDHEWF
.|||| ||...||.|||||..||.|..|
AIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase KNS1.AA DYRK1 482-571 36 5.1e-15 48.73 In-house 141-229 (321) Show / Hide 
Range on Protein: 482-571
Range on HMM: 141-229/321
Sequence Identity: 36% (33 aa)

KNPEIKIIDFGSAIFHYEYHPPVISTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVIGESLYPIHENLEHMAMMQRINGTPFPTDIIDK
|   ||||||||.    .     |  | ||.||..||. ...  |.||. |.|||. .|| |.   . .. |  .  . | | | ..||.
KRSAIKIIDFGSSCQLGQRIYQYIQSRFYRSPEVLLGIEYDMAIDMWSLGCILVEMHTGEPLFSGSNEVDQMNKIVEVLGMP-PKHMIDQ
Kinase KNS1.AA YAK 480-540 40 5.4e-13 40.09 In-house 138-201 (347) Show / Hide 
Range on Protein: 480-540
Range on HMM: 138-201/347
Sequence Identity: 40% (26 aa)

ILKN---PEIKIIDFGSAIFHYEYHPPVISTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVIG
.|..   ||||||||||.          |  ||||.|||...   .   | ||  |...||  |
MLCKPNKPEIKIIDFGSSCQEKKMVYTYIQQRHYRSPEIIVWMIYCTSIDMWSLGCIVAELFLG
Kinase KNS1.AA HIPK 486-545 45 8.5e-13 36.14 In-house 144-204 (329) Show / Hide 
Range on Protein: 486-545
Range on HMM: 144-204/329
Sequence Identity: 45% (28 aa)

IKIIDFGSA-IFHYEYHPPVISTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVIGESLYP
.|.|||||| ..      . .  |.||||||.|||      |.||  ||. ||  |  |||
VKVIDFGSASHVSKVVCNTYLQSRYYRAPEIILGLPFCENHDMWSLGCVIAELFLGWPLYP
Kinase KNS1.AA DYRK 693-720 50 1.1e-12 43.99 In-house 293-320 (320) Show / Hide 
Range on Protein: 693-720
Range on HMM: 293-320/320
Sequence Identity: 50% (14 aa)

FIDLLRKMFEFDPTKRITAKDALDHEWF
|.|...|....||.||||...||.| ||
FKDFIKKCLQWDPHKRITPSQALQHPWF
Kinase KNS1.AA CAMK 694-720 48 1.2e-12 36.31 In-house 399-425 (425) Show / Hide 
Range on Protein: 694-720
Range on HMM: 399-425/425
Sequence Identity: 48% (13 aa)

IDLLRKMFEFDPTKRITAKDALDHEWF
.||.||| . ||.||.|....|.|.|.
KDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase KNS1.AA Ciliate-E2 694-720 43 1.3e-12 39.64 In-house 334-365 (365) Show / Hide 
Range on Protein: 694-720
Range on HMM: 334-365/365
Sequence Identity: 43% (14 aa)

IDLLRK----MFEFDPTKRIT-AKDALDHEWF
.||..|    |.. || |||| ....|.|.||
KDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase KNS1.AA DYRK2 693-720 46 2.6e-11 32.68 In-house 291-318 (318) Show / Hide 
Range on Protein: 693-720
Range on HMM: 291-318/318
Sequence Identity: 46% (13 aa)

FIDLLRKMFEFDPTKRITAKDALDHEWF
||| ... || ||..|.|...||.|.|.
FIDFIKRCFEWDPSERMTPSQALKHPWI
Kinase KNS1.AA Pkinase 692-720 37 1.2e-09 35.19 Pfam 265-293 (293) Show / Hide 
Range on Protein: 692-720
Range on HMM: 265-293/293
Sequence Identity: 37% (11 aa)

WFIDLLRKMFEFDPTKRITAKDALDHEWF
...|........||.||.||...| |.||
ECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase KNS1.AA TyrKc 313-638 15 1.2e-07 -99.08 SMART 1-280 (280) Show / Hide 
Range on Protein: 313-638
Range on HMM: 1-280/280
Sequence Identity: 15% (56 aa)

FVVKDLLGQGTFGKVLKCIDNKYEPNYVAVKVIRAVDRYREAAKTELRILQTILNNDPQG-QFQCL--LLRECFD------YKNHICLVTDLY-GRSIYD
 . .. || | ||.| |.. .      ||||....    ||.   |.||.  .      | . ...  |.  | .      |   ...|. .  . .  |
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA--REDFMREARIMCKL------GGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

FMCSNGIARFPGSHIQAIARQLIRSVCFLHDLGIIHTDLKPENILICDETHIAQKLPLKTVQSLSKRRREASKGKRKILKNPEIKIIDFGSAIFHYEY--
.  ...   .. ..   .. |  .   .||. ..|| ||   |.|. ..                                  .|| ||| . ..|..  
YLRKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--------------------------------TVKISDFGLSRDIYDDDQ

---HPPVISTR---HYR--------APEIVLGLGWSFPCDIWSIACVLVELV-IGESLYPI-----HENLEHMAMMQRINGTPFPTDIIDKMFYKSKHKL
      .....   . .        |||       ..  |.||   .. |.   |.. ||       .| | ..  .. .  | | ..   |        
QGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYP-MS-------

GNSPSDLNSTVIKHFDRKTLSLQWPEKNKRGDTITTEKSMKRVLQSCDRLDIY-------ISKVL
                                  .  . | .. ..| . |         | . .
--------------------------------FVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase KNS1.AA DYRK1 693-720 46 1.2e-07 22.44 In-house 294-321 (321) Show / Hide 
Range on Protein: 693-720
Range on HMM: 294-321/321
Sequence Identity: 46% (13 aa)

FIDLLRKMFEFDPTKRITAKDALDHEWF
| ||...| ..|| .|||  .|| |..|
FKDLIKRMLQYDPKQRITPYYALQHSFF
Kinase KNS1.AA STE 693-720 36 5.4e-07 20.87 In-house 330-359 (359) Show / Hide 
Range on Protein: 693-720
Range on HMM: 330-359/359
Sequence Identity: 36% (11 aa)

FIDLLRKMFEFDPTKRITAKDALD--HEWF
|.| ..| .. || || ||.. |   |...
FKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase KNS1.AA HIPK 693-720 42 2.1e-05 12.43 In-house 302-329 (329) Show / Hide 
Range on Protein: 693-720
Range on HMM: 302-329/329
Sequence Identity: 42% (12 aa)

FIDLLRKMFEFDPTKRITAKDALDHEWF
|...|.||   |. ||||  .||.|.. 
FVHVLKKMCTWDAHKRITPCEALNHPFV
Kinase KNS1.AA YAK 693-720 25 0.004661 5.79 In-house 320-347 (347) Show / Hide 
Range on Protein: 693-720
Range on HMM: 320-347/347
Sequence Identity: 25% (7 aa)

FIDLLRKMFEFDPTKRITAKDALDHEWF
|||..  . . .| .| ..  |  |   
FIDFINQLLQLNPRERWKPMQAMQHPFI