Gene RIO2 (Bakers Yeast)

RIO2

Species: Bakers Yeast
Alias: RIO2
External Links: Saccharomyces Genome Database Link ,
Annotation:

Classification

Group: Atypical
Family: RIO
Subfamily: RIO2

Sequence

Name Sequence Type Origin Length Description Download
RIO2.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 318 Kinase domain by global Sugen HMM Fasta, JSON
RIO2.AA Protein Refseq_NP 425 Protein required for cell viability; Rio2p [Saccharomyces cerevisiae] Fasta, JSON

Protein domain

Protein domains of RIO2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase RIO2.AA RIO2 73-333 68 3.6e-221 741.04 In-house 1-260 (260) Show / Hide 
Range on Protein: 73-333
Range on HMM: 1-260/260
Sequence Identity: 68% (180 aa)

YRLTYNGIDYLALKTMLNRDTVYSVGNTIGVGKESDIYKVSDKNGNPRVMKIHRLGRTSFHSVRNNRDYLKKSNQGANWMHLSRLAANKEYQFMSMLYSK
||||  | |||||||.  |  ||||||..||||||||||.|..|||...||.|||||||||...|||||.|...| ..||.||||.|.||||||.|||..
YRLTNAGYDYLALKTLSSRQVVYSVGNQMGVGKESDIYKCSNENGNQFIMKFHRLGRTSFHNIKNNRDYHKHRHQ-YSWMYLSRLSAMKEYQFMDMLYKR

GFKVPEPFDNSRHIVVMELIEGYPMRRLRKHKNIPKLYSDLMCFIVDLANSGLIHCDFNEFNIMIKDKLEDENDCGFVVIDFPQCISIQHQDADYYFQRD
.|.||.|.|..|||||||||.||||.....|.|.|..|...|||||.|||.|||||||||||.||.|...|||||||..|||||..|.|||.|..||.||
NFPVPKPIDYNRHIVVMELINGYPMCQIHHHDNPPYVYDQCMCFIVRLANHGLIHCDFNEFNLMIDDNDHDENDCGFIMIDFPQMVSTQHQNAQWYFDRD

VDCIRRFFKKKLKYEPKPDSSMLDTEGFGDGYKYAYPDFKRDVKRTDNLDELVQASGFSKK
||||.|||.|...|||||..|||||||||||||||||||.||..|||.|||.||||||.||
VDCIHRFFMKRFNYEPKPFPSMLDTEGFGDGYKYAYPDFFRDIQRTDTLDEEVQASGFNKK
Kinase RIO2.AA RIO 73-326 46 3.7e-174 584.87 In-house 1-276 (276) Show / Hide 
Range on Protein: 73-326
Range on HMM: 1-276/276
Sequence Identity: 46% (129 aa)

YRLTYNGIDYLALKTMLNRDTVYSVGNTIGVGKESDIYKVSDKNGN-----------PRVMKIHRLGRTSFHSVRNNRD---YLKKSNQGANWMHLSRLA
|..|  . .......|.||  |.||||.||||||||||..|..||.           ....||||.|||||......||   |.|......||....||.
YEQTNDPYTRMIMYKMVNRGMVESVGNCIGVGKESDIYHCSNENGEDEKEDSKVIPTECAIKIHRTGRTSFKDRKKYRDGEFYFKHRHCKHNWRYMHRLW

ANKEYQFMSMLYSKGFKVPEPFDNSRHIVVMELIEG-------YPMRRLRKHKNIPKLYSDLMCFIVDLANSG-LIHCDFNEFNIMIKDKLEDENDCGFV
|.||...|..||..||..|||.|..||..|||.|..       |||.....|.|....|...||....|.... |.||||||||.|..|...|||||||.
AEKEMRNMKRLYQSGFPCPEPIDYKRHVLVMEFINHDQMPAPKYPMCQIHEHENMKHVYHQCMCYMRRLYQHCRLVHCDFNEFNMMWHDGKHDENDCGFY

VIDFPQCISIQHQDADYYFQRDVDCIRRFFKKKLKYEPKPDSSMLDTEGFGDGYKYAYPDFKRDVKRTDNLDELVQ
.|||||.....|..|..||.||..|...||.|...|||.|...|.|..|||||||||||||||||||||.||....
MIDFPQMVEHDHPHALWYFRRDCKCVNMFFMKRFVYEPFPEREMFDFVGFGDGYKYAYPDFKRDVKRTDTLDHENM
RIO RIO2.AA RIO 66-302 26 8.4e-110 372.01 SMART 1-253 (253) Show / Hide 
Range on Protein: 66-302
Range on HMM: 1-253/253
Sequence Identity: 26% (67 aa)

RNVKYDGYRLTYNGIDYLALKTMLNRDTVYSVG--NTIGVGKESDIYKV----SDKNGNPRVMKIHRLGRTSFHSVRNNRDYLKKSN---QGANWMHLSR
 ...|..|...........|..|.||.......  ..|..|||...|..    .|||||....||.|...|.|......... ....   ...||....|
DKEDYATYEEVFDPRTRMTLYKMVNRGYIEEINNHGCISTGKEANVYHAMGGDFDKNGNECAVKIYRTSTTEFKRMWRYIQGDFRFKHGYHHINWRKMVR

LAANKEYQFMSMLYSKGFKVPEPFDNSRHIVVMELIEG--YPMRRLRKHKNIP-------KLYSDLMCFIVDLANSG-LIHCDFNEFNIMIKDKLEDEND
|.|.||.......|..|...|.|....||..|||.|..  .|..||.......       ..|...|.......... |.|.|..|.|....| ||||||
LWAEKEFRNLQRMYEAGVPCPKPIAWRRHVLVMEFIGDDGWPAPRLKDVEWEEWEMDFKWEYYWQIMEYMRKMYHECHLVHADLSEYNMLYHD-LEDEND

CGFVVIDFPQCISIQHQDADYYFQRDVDCIRRFFKKKLKYEPKPDSSMLDTEGFGD
|....||..|.....|........||...|..||..| ......  .. ..|....
CKVWIIDWSQSVECDHPMWLEFLERDIWNIINFFRRKGVDCDDI--YREIFERITG
Rio2_N RIO2.AA Rio2_N 8-91 61 3.3e-50 171.78 Pfam 1-84 (84) Show / Hide 
Range on Protein: 8-91
Range on HMM: 1-84/84
Sequence Identity: 61% (52 aa)

MRYLTTDDFRVLQAVEQGSRSHEVVPTPLIHQISGMRSQSGTNRAISDLAKLSLISKMRNVKYDGYRLTYNGIDYLALKTMLNR
||||. .|||||.|||.|.| ||.||| ||||||..|| .|.....|.|.|. |||...|.|||||||||.| |||||.|...|
MRYLSKEDFRVLTAVEMGMRNHEWVPTELIHQISRLRSHGGCHYRLSRLCKHKLISHVQNKKYDGYRLTYGGYDYLALHTFVKR
Kinase RIO2.AA RIO1 108-293 26 4.7e-45 140.96 Pfam 1-200 (200) Show / Hide 
Range on Protein: 108-293
Range on HMM: 1-200/200
Sequence Identity: 26% (54 aa)

DIYKVSD-KNGN-PRVMKIHRLGRTSFHSVRNNRDYLKK----SNQGANWMHLSRLAANKEYQFMSMLYSKGFKVPEPFDNSRHIVVMELIE---GYPMR
..|.. .  .|. ....||.|.|.|.|  ..  ||| .      ... ||  ..|..|.||. ... .|  |...|.| |  ||..|||.|    |.|. 
NVYHAYSMEDGKDECAVKIYRTGTTCFKKMKRYRDYDFRFRHRYHHH-NWRYMVRMWAEKEFRNLKRMYEAGVPCPKPIDWNRHVLVMEFIGDKDGWPAP

RLRKHK--------NIPKLYSDLMC--FIVDLANSGLIHCDFNEFNIMIKDKLEDENDCGFVVIDFPQCISIQHQDADYYFQRDVDCIRRFFKKKLKY--
||.           ... .| ...    .. ... ||.|.|..|.||.. |      | ....||.||  ...| .|  .. ||...| .||..|  .  
RLKDVEMELELSEEEAEEIYDEIIREYMRRMYQECGLVHGDLSEYNILVHD------DGKPWIIDWPQAVEHDHPHALEFLERDCRNIINFFRRKGVDER

EPKPDSS
.. ... 
VMDFREI