Gene YDR466W (Bakers Yeast)

YDR466W

Species: Bakers Yeast
Alias: YDR466W
External Links: Saccharomyces Genome Database Link
Annotation:

Classification

Group: AGC
Family: PDK1

Sequence

Name Sequence Type Origin Length Description Download
YDR466W.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 283 Kinase domain by global Sugen HMM Fasta, JSON
YDR466W.AA Protein Refseq_NP 898 Hypothetical ORF; Ydr466wp [Saccharomyces cerevisiae] Fasta, JSON

Protein domain

Protein domains of YDR466W.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase YDR466W.AA PDK1 11-293 46 2.2e-207 642.0 In-house 1-307 (307) Show / Hide 
Range on Protein: 11-293
Range on HMM: 1-307/307
Sequence Identity: 46% (145 aa)

FIFKEELGHGSYSTVFKALDKKSP---NKIYAIKVCSKKHIIKEAKVKYVTIEKNTMNLLAQKH--HAGIIKLYYTFHDEENLYFVLDFAPGGELLSLLH
|||....|.||||||..|..|...   ||.||||.|.|..||.|.|||||..||..|..|....  |.||.|||.||.||..|||||...|.|.||....
FIFGKNIGEGSYSTVYLAREKETKNDENKMYAIKICEKRYIIREKKVKYVHREKEIMCHLNNECNGHPGIVKLYFTFQDEQCLYFVLEYCPNGDLLHYMK

K--MGTFNDIWTRHFTAQLIDALEFIHSHGIIHRDLKPENVLLDRDGRLMITDFGAA---ATIDPSLSGDSAKFNS----DSNGSK-----DNQNCASFV
|  .|.|.....|...|..|||||..||.|||||||||||.|||.|...||||||.|   .......|.....|..    ...|..     ....|.|||
KQPFGSFDMDCCRFYAAEIIDALEHLHSNGIIHRDLKPENILLDKDMHIMITDFGTAGFDKILPEYQSQQQNQFQQQFQQHNKGMDKPEEDKQTRCKSFV

GTAEYVSPELLLYNQCGYGSDIWALGCMIYQFVQGQPPFRGE-----NELKTFEKIVALDYPWGPNNRINNSTSPINPLVINLVQKILVIEVNERIS---
||||||||||| ...|....|||||||.|||.|.|||||||.     ||..||.||....|....|.|       ..| ...||.|.||...|.|..   
GTAEYVSPELLTDKECTPSCDIWALGCIIYQMVAGQPPFRGMNDATNNEYHTFQKIMKCQYDFPDNFR-------FPPCAKDLVKKLLVRDPNDRLTSCD

----LEQIKRHPYF
    ..|||.||.|
ECGGYQQIKAHPFF
Kinase YDR466W.AA AGC 11-293 26 4.6e-131 340.81 In-house 1-395 (395) Show / Hide 
Range on Protein: 11-293
Range on HMM: 1-395/395
Sequence Identity: 26% (107 aa)

FIFKEELGHGSYSTVFKALDKKSP-----NKIYAIKVCSKKH---IIKEAKVKYVTIE------------KNTMNLLAQKH-------HAGIIK-LYYTF
| |.  .| ||...|. . .|...     .|.||.||..|||   |.|. .|... .|            .| . .. ..|       |  |.| |.|.|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

HDEEN--LYFVLDFAP---------GG-ELLSLLH---KMGTFNDIWTRHFTAQ-------LIDALEFIHS-HGIIHRD-LKPENVLLDRDGRLMITDFG
.|...  ||||....|         || ||.. |.   | |.|.  ..|...|.       .. |||..|| .|||||| |||||.|||.|| ...||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

AAATIDPS---------LSGDSAKFNSDSNGSKDN------------------------------QNCASFVG--TAEYVSPELLLYNQCGYGSDIWA--
 .  .  .         .     ||.. .|. . .                              . . .|.|  |.||..|| |    .|.  |.|.  
LCKEGMNDGEKGQQSQSN----MKFHW-HNKKY-QKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFG

LGCMIYQFVQGQPPFRGEN----------ELKTFEKIVALDYPWGPNNRINNST-------SPINPLVINLVQKILVIEVNERIS----------LEQIK
|||..|... |.|||.|.|          . ..|.||   .| .  . .... .       . . |   .|..| |. . ..|.            |.||
LGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIK

RHPYF
.||.|
NHPWF
Kinase YDR466W.AA S_TKc 11-293 27 3.9e-95 323.27 SMART 1-231 (231) Show / Hide 
Range on Protein: 11-293
Range on HMM: 1-231/231
Sequence Identity: 27% (82 aa)

FIFKEELGHGSYSTVFKALDKKSPNKIYAIKVCSKKHIIKEAKVKYVTIEKNTMNLLAQKHHAGIIKLYYTFHDEENLYFVLDFAPG--GELLSLLHKMG
. . ...|.|....|.|. .||  ..|.|||. .          . .  | . .      ||  |.|||..|.| ..||.|.....|  |.|.....|.|
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK----------EHIRREIQILKK----HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRG

T------FNDIWTRHFTAQLIDALEFIHSHGIIHRDLKPENVLLDRDGRLMITDFGAAATIDPSLSGDSAKFNSDSNGSKDNQNCASFVGTAEYVSPELL
.      |.  ..|....|...|||..||||||||||||||.|||.  ...|.||| |. .                         .|.|| .|..||.|
RHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------------------------TTFCGTPWYMAPEVL

LYNQCGY-GSDIWALGCMIYQFVQGQPPFRGENELKTFEKIVALDYPWGPNNRINNSTSPINPLVINLVQKILVIEVNERISLEQIKR-------HPYF
   . |.  .|.|..||..| .. |.|||.  .. ..|.||.                    | ......|.|. . ..|..  .. .       ||.|
---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase YDR466W.AA CAMK 16-293 21 7.7e-79 253.51 In-house 1-425 (425) Show / Hide 
Range on Protein: 16-293
Range on HMM: 1-425/425
Sequence Identity: 21% (91 aa)

ELGHGSYSTVFKALDKKSPN-----------KIYAIKVCSKKHIIK-------------------------EAKVKYVTIEKNTMNLLAQKH----HAGI
.||.||...|... .|....           . .|||. .|| . .                         . . | |  | . |..| ...    |  |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKLYYTFHD-------------------EENLYFVL---DFAPGGEL----LSLLHKM---------------GTFNDIWTRHFTAQLIDALEFIHSHGI
|||| .. |                   ....|.|.   ....||||    .. . .                | |.   .|..  |...|....|||.|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDLKPENVLLDRD-----------------GRLMITDFGAAATIDP-SLSGDSAKFNSDSNGSKD-------NQNCASFVGTAEYVS-PELLLYNQ--
.||||||||.||| .                 . . |.||| |. .|| . . . ..... .   ..       .| .  |.|| ||.. ||.|....  
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-M-HNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC

------------CGYGSDIWALGCMIYQFVQGQPPFRGE-------------NELKTFEKIVALDY--PWGP------------NNRINNS--TSPINPL
            .|. .|.|..|.. |  . | |||.|.             |. ..|||| . .|  |. .             ..| ..     . . 
NMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHH-FVSQE

VINLVQKILVIEVNERISLEQIKRHPYF
...|..|.|. . ..|...||...|| .
CKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase YDR466W.AA Pkinase 11-293 24 7.3e-75 259.82 Pfam 1-293 (293) Show / Hide 
Range on Protein: 11-293
Range on HMM: 1-293/293
Sequence Identity: 24% (77 aa)

FIFKEELGHGSYSTVFKALDKKSPNKIYAIKVCSKKHIIKEAKVKYVTIEKNTMNLLAQKHHAGIIKLYYTFHDEENLYFVLDFAPGG----ELLSLLH-
. ... .| ||...|.|. .|...  |.|.|. .|.|. .. ..  . .  .   ...  .|  |..||..|.|. ..|.|.....||    .| .... 
YHIGRKIGSGSFGCVYKCHHKGTGK-IVAVKIIKKRHEKSWKDQTHRRL--SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST

-KMGTF--NDIWTRHFTAQLIDALEFIHSHGIIHRDLKPENVLLDRDGRL----MITDFGAAATIDPSLSGDSAKFNSDSNGSKDNQNCASFVGTAEYVS
 . |.|   .   ...  |.. .||..||.|||||||||||.|.|..| .     |.||| |. .|                   |. . .|.|| .|..
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----------------Y-NNS-MTTFCGTPWYMA

PELLL-YNQCGYGSDIWALGCMIYQFVQGQPPFRGE------NELKTFEKIVALDYPWGPNNRINNSTS------------PINPLVINLVQKILVIEVN
||... ..  |. .|.|..||..|... |.|||.|.      .... ...|   ....   . ...|..             ...  . .. ..|    .
PEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPK

ERISLEQIKRHPYF
.|.. |||. ||.|
KRPTAEQILQHPWF
Kinase YDR466W.AA Ciliate-E2 11-293 22 4.7e-72 245.7 In-house 1-365 (365) Show / Hide 
Range on Protein: 11-293
Range on HMM: 1-365/365
Sequence Identity: 22% (84 aa)

FIFKEELGHGSYSTVFKALDKKSPN----------------------KIYAIKVCSKKHIIKEAKVKYVTIEKN-------TMNLLAQKHHAGIIKLYYT
..| . .| |....|.|. ..| ..                      ||||.|. .|. |.   .....  |.|        .|.| |  |  |||.|..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FH--DEENLYFVLDFAPGGELLSLLHKM-----------GTFNDIWTRHFTAQLID---------------ALEFIHSHG-IIHRDLKPENVLLDRDGRL
|   |..|.|.|.... ||.|.... ..           . |..   .....|...               |||..|| . |||||.||||.|.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

MITDFGAAATIDPS--------LSGDSAKFNSDSNGSKD-------NQNCASFVGTAEYVSPELLLYNQ---------CGYGSDIWALGCMIYQFVQGQP
 |.||| .  .|..        ...     ..| ...          .   ...||..|..|| | . .          .| .|||.||...|... |.|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFRGENELKTFEKIVALDYPWGPNNRINN---------STSPINPLVINLVQK----ILVIEVNERIS-LEQIKRHPYF
||        ...|   ..   ... ...         |.  . . ...| .|    .|. . ..||.  |||. ||.|
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase YDR466W.AA Ciliate-E2-Unclassified 11-293 24 1.3e-69 237.6 In-house 1-352 (352) Show / Hide 
Range on Protein: 11-293
Range on HMM: 1-352/352
Sequence Identity: 24% (90 aa)

FIFKEELGHGSYSTVFKALDKKSPNKIYAIKVCSKKHIIKEAKVKYV------TIEKNTMN-------------LLAQKHHAGIIKLYYTFHDEENLYFV
... . .|.|....|.|. .||   ..||.|  .|..|.|  .....       .| | ..             .| .  |  |.|..|.| |..|.|.|
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

LDFAPGGELLSLLHKMGT-----------------FNDIWTR-----HFTAQLIDALEFIHSHG-IIHRDLKPENVLLDRDG---RLMITDFGAAATIDP
.....||.|.  . |...                 | .  ..     ...||....||..|. . |||||.||||.|.| .|   .. |.||| .  .. 
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

S-------LSGDSAKFNSDSNGSKDNQN----CASFVGTAEYV----SPELLLYNQCG----YGSDIWALGCMIYQFVQGQPPFRGENELK---------
.       .              | ...    . .|.|| .|     .||.|  .. .    | .|||.||. .|... |..|| ..|. .         
NNNCDTNQQ-------------QKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWI

-------TFEKIVA--LDYPWGPNNRINNSTSPINPLVIN-LVQKILVIEVNERISLEQIKRHPYF
        ...| .  ...|. |.  |    ||     || | ||.|.   |.||..|||. ||.|
NNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase YDR466W.AA ULK 11-293 24 9.7e-62 211.42 In-house 1-324 (324) Show / Hide 
Range on Protein: 11-293
Range on HMM: 1-324/324
Sequence Identity: 24% (86 aa)

FIFKEELGHGSYS-TVFKALDKKSP--NKIYAIKVCSKKHIIKEAKV-------KYVTIEKNTMNLLA---QKHHAGIIKLYYTFHDE--ENLYFVLDFA
.. ...||.||.  .|.|. .||.   |...|.|. .|| ..|  .        .    | ..|  |     ..|  |.|||  | .    |.|..... 
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNH-HIVKLYDWFETSNHNNIYIIMEYC

PGGELLSLLHKMGTFNDIW----------TRHFTAQLIDALEFIHSHGIIHRDLKPENVLLDRD------------GRLMITDFGAAATIDPSLSGDSAK
.|| | ....| ....             ...|  |.. .. ..|.|.|||||.||.| |.  .            |.| |.||| | ..|         
NGGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVD---------

FNSDSNGSKDNQNCASFV------GTAEYVSPELLLYN--QCGYG---SDIWALGCMIYQFVQGQPPFRGENELKTF----------------EKIVALD
     |.... | | ..|      ||  | .|..|  .  |. |.   .||| |||..|. . |..||..    ...                .|   ..
-----NNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQ

YPWGPNNRINNSTSPINPLVINLVQKILVIEVNERISLEQIKRHPYF
.| .|      .  .| | ...| .. |... ..||| |.|  || |
FPKPP------KDPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase YDR466W.AA ULK 11-293 24 3.1e-61 209.75 In-house 1-329 (329) Show / Hide 
Range on Protein: 11-293
Range on HMM: 1-329/329
Sequence Identity: 24% (83 aa)

FIFKEELGHGSYSTVFKALDKKSP---NKIYAIKVCSKKHIIKEAKVKY-------VTIEKNTMNLLAQK-----HHAGIIKLYYTFHDE--ENLYFVLD
.. ...||.||. .|.|. .||.    |...|.|. .|. .... .  .       .. |  .|  | ..     ||  |.|||  | .    |.|....
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

FAPGGELLSLLHKMGTF-------NDIW---TRHFTAQLIDALEFIHSHGIIHRDLKPENVLLDRD------------GRLMITDFGAAATIDPS-LSGD
. .|| | ....| ...       . .    ...|  |.. .. ..|.|.|||||.||.|.|.. .            |.| |.||| | ..| . .. .
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

SAKFNS-DSNGSKDNQNCASFVGTAEYVSPELLLYN--QCGYG---SDIWALGCMIYQFVQGQPPFRGE-NELK--TFEKIVALDYPWGP---NNRIN-N
 ..  . .    |       . ||  | .|..|  .  |. |.   .||| |||..|. . |.|||..  |...    .| . . .||..   .. .. .
MMMTCVNE----K------RLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFP

---STSPINPLVINLVQKILVIEVNERISLEQIKRHPYF
   .  .| | ...| .. |... ..||| |..  || |
KDGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase YDR466W.AA CAMKL 11-293 25 2.4e-60 191.23 In-house 1-297 (297) Show / Hide 
Range on Protein: 11-293
Range on HMM: 1-297/297
Sequence Identity: 25% (82 aa)

FIFKEELGHGSYSTVFKALDKKSPNKIYAIKVCSKKHIIK-------------EAKVKYVTIEKNTMNLLAQKH-HAGIIKLYYTFHDEEN------LYF
... ..||.||...|  |.... ... .|||.  || | .             |...  .. | . | .|  .  |  ||||| .. ..|.      .| 
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLN-IGKHPNIIKLYEVIETPEHDIETKKIYL

VLDFAPGGE--LLSLLHKM----GTFNDIWTRHFTAQLIDALEFIHSHGIIHRDLKPENVLLDRDG--RLMITDFGAAATID-PSLSGDSAKFNSDSNGS
|.  ..|||  |.  . |     | .    .|..  |...|....|||||.|||.||||.||| .|   . |.||| .. ..                  
VMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPC--------------IF

KDNQNCASFVGTAEYVSPELLLY--N-QCGYGSDIWALGCMIYQFVQGQPPFRGE--------NELKTFEKIVALDYPWGPNNRINNSTSPINP-LVINL
...| .  | |. .| .||...      .|.  |||..| . |  | |. ||...        |  . ..||  . | . .         .. .  ...|
GPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPI---------WYHVSDCRDL

VQKILVIEVNERISLEQIKRHPYF
 .|.|.   ..|....||..|| .
IRKMLQVNPEKRPTIHQIMNHPWM
Kinase YDR466W.AA RSK 13-242 30 2.7e-55 190.01 In-house 1-227 (278) Show / Hide 
Range on Protein: 13-242
Range on HMM: 1-227/278
Sequence Identity: 30% (76 aa)

FKEE--LGHGSYSTVFKALDKKSPNKIYAIKVCSKKHIIKEAK-VKYVTIEKNTMNLLAQKHHAGIIKLYYTFHDEENLYFVLDFAPGGELLSLLHKMGT
 |.   .| |..... |  .... ..||| || .|. |.. .| ....  | |   |.. ..|  |..|.|.|..|. || .... .||||.  | | ..
LKVLGQGGYGKVFLCRKCTHHDT-GQIYAMKVLKKAKIVQRQKDTRHTMTERNI--LERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKH

---FNDIWTRHFTAQLIDALEFIHSHGIIHRDLKPENVLLDR---DGRLMITDFGAAATIDPSLSGDSAKFNSDSNGSKD-NQNCASFVGTAEYVSPELL
   |     .   |... |.|..|..|||||||||||.|.|    .|....|||| .                    . | ||   .|..|.||. ||.|
FGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF-----------------RCDHNQWTMTFCYTIEYMAPEML

L--YNQCGYGS--DIWALGCMIYQFVQGQPPFRG---ENELKTFEKI
   . |.|..   |.| ||. .|    |.|||.|   .|  .....|
KRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRI
Kinase YDR466W.AA Akt 11-158 40 2.1e-42 133.33 In-house 1-146 (264) Show / Hide 
Range on Protein: 11-158
Range on HMM: 1-146/264
Sequence Identity: 40% (61 aa)

FIFKEELGHGSYSTVFKALDKKSPNKIY-AIKVCSKKHIIKEAKVKYVTIEKNTMNLLAQKHHAGIIKLYYTFHDEENLYFVLDFAPGGELLSLLHKMGT
| |.. || ||.  || . .|.. .|.| |.|| .|..||.  .|...  |.   |.|    |  |..|.| | ....||||.|...|||| ..|.. ..
FDFLKVLGKGSFGKVFLVKKKDT-QKWYYAMKVLKKDYIIQKNQVEHTKTER---NILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRR

FNDIWTRHFTAQLIDALEFIHSHGIIHRD-LKPENVLLDRDGRLMITDFG
|.   .| . |..| |.|. ||..|| || |||||.|.|.|| . .||||
FSEDRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFG
Kinase YDR466W.AA Akt 182-247 35 4.8e-15 44.45 In-house 154-220 (264) Show / Hide 
Range on Protein: 182-247
Range on HMM: 154-220/264
Sequence Identity: 35% (24 aa)

KDNQNCASFVGTAEYVSPELLLYNQCGYGSDIWA-LGCMIYQFVQGQPPFRGENELKTFEKIVALDY
||.. . .| ||.|| .|| |. | ..  .|.|. ||| .| . .|.|||  ..  . |.||   ..
KDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPFYNQDHHQMFKKIKNQPV
Kinase YDR466W.AA TyrKc 11-293 20 8.1e-13 -15.47 SMART 1-280 (280) Show / Hide 
Range on Protein: 11-293
Range on HMM: 1-280/280
Sequence Identity: 20% (62 aa)

FIFKEELGHGSYSTVFKALDKKSPNKIYAIKVCSKKHIIKEAKVKYVTIEKNTMNLLAQ-KHHAGIIKLYYTFHDE-------ENLYFVLDFAPGGELLS
  ....||.| . .|.|.  |       |.|.. . .           . .    .    .||  |..||    ..       | |. |. ..|.| |..
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA--------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

LLHKMGT-FNDIWTRHFTAQLIDALEFIHSHGIIHRDLKPENVLLDRDGRLMITDFGAAATIDPS-LSGDSAKFNSDSNGSKDNQN-----CASFVGTAE
 |.| .  ..     .|  |  .  |..||...|||||   |.|......  |.||| .  |.    .|           |||        .. ..    
YLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG----------ESKDYYRKKEHKGGKTMLPIR

YVSPELLLYNQCGYGSDIWALGCMIY-QFVQGQPPFRG-----ENELKTFEKIVALDYPWGPNNRINNSTSP-----INPLVINLVQKILVIEVNERISL
  .|| . |. .   ||.|. | ...  |  ||.|  |      .    .|.. . ...  | |       |       . . .. ..    . ..| . 
WMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-----PMSFVCCPDEMYQIMKQCWHEDPEDRPTF

EQIKRHPYF
..|  | .|
SEI--HECF
Kinase YDR466W.AA Pkinase_Tyr 83-158 28 2.6e-07 25.41 Pfam 75-156 (270) Show / Hide 
Range on Protein: 83-158
Range on HMM: 75-156/270
Sequence Identity: 28% (23 aa)

HDEEN--LYFVLDFAPGGELLSLLHKM----GTFNDIWTRHFTAQLIDALEFIHSHGIIHRDLKPENVLLDRDGRLMITDFG
...|   .| |. ..|.| ||. |.|     . ..  .  .. .|  ...|. .|...|||||   |.|.....   |.|||
DQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase YDR466W.AA RSK 268-293 32 6.8e-05 14.24 In-house 248-278 (278) Show / Hide 
Range on Protein: 268-293
Range on HMM: 248-278/278
Sequence Identity: 32% (10 aa)

NLVQKILVIEVNERIS-----LEQIKRHPYF
.|..| |  . . |..     .|.||.||.|
DLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase YDR466W.AA Akt 284-293 60 0.002043 6.69 In-house 255-264 (264) Show / Hide 
Range on Protein: 284-293
Range on HMM: 255-264/264
Sequence Identity: 60% (6 aa)

LEQIKRHPYF
...|||||.|
AQEIKRHPWF
Kinase YDR466W.AA Pkinase_Tyr 11-28 33 0.2262 5.27 Pfam 1-18 (270) Show / Hide 
Range on Protein: 11-28
Range on HMM: 1-18/270
Sequence Identity: 33% (6 aa)

FIFKEELGHGSYSTVFKA
 .| ..||.|.. .|.|.
ITFGKKLGEGAFGEVYKG