Gene LMR1 (Human)
LMR1
Sequence
Protein domains of LMR1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | LMR1.AA | Lmr | 125-398 | 73 | 8e-230 | 769.79 | In-house | 1-283 (283) | Show / Hide |
Range on Protein: 125-398 Range on HMM: 1-283/283 Sequence Identity: 73% (207 aa) LLYLKEIGRGWFGKVFLGEVNS---GISSAQVVVKELQASASVQEQMQFLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSCRVAE |.|..|||.||||||.||||.| |.|.||||||||.||||.|||||||.||||||.|.|.|.||||.||.|..||||||||||.||||.|||.||..| LNYIQEIGNGWFGKVLLGEVHSLHPGMSKAQVVVKELRASASPQEQMQFLQEVQPYRELQHPNVLQCLGQCVETIPYLLVMEFCPYGDLKNYLRKCRPME SMAPDP-----RTLQRMACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKIGDYGLAHCKYREDYFVTADQ-LWVPLRWIAPELVDEVHSNLLVVDQT .|.||. .||||||||.|||..|.|...|||||||||||.|.|||||||||||||||.|.|||..|.|| .|||||||||||.||.|.|||||||| HMMPDKPPRQTMTLQRMACEIACGLAHMHQHHFVHSDLALRNCQLCADLTVKIGDYGLAHCQYKEDYYITKDQCHWVPLRWIAPELMDEFHQNLLVVDQT KSGNVWSLGVTIWELFELGTQPYPQHSDQQVLAYTVREQQLKLPKPQLQLTLSDRWYEVMQFCWLQPEQRPTAEEVHLLLSYL |..|.||||||.|||||...||||.|||.||||..||||..|||||||||..||||||.|||||.||.||||||.||.||.|| KYSNIWSLGVTMWELFEFAAQPYPHHSDEQVLAQVVREQDIKLPKPQLQLPYSDRWYEIMQFCWMQPDQRPTAEDVHRLLTYL |
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Kinase | LMR1.AA | TK | 125-395 | 19 | 4.2e-83 | 278.33 | In-house | 1-486 (486) | Show / Hide |
Range on Protein: 125-395 Range on HMM: 1-486/486 Sequence Identity: 19% (95 aa) LLYLKEIGRGWFG---KVFLGEVNSGI-----------------------SSAQVVVKELQ--ASASVQEQMQ--------------FLEEVQPYR--AL . ..|..|.|.|| .|..||..... .| || | ...| .|... ..|| . . .. ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG KHSNLLQCLAQCAEV------------TPYLLVMEFCPLGD----LKGYLRSCRVAESM----------------------------------------- .| |...... | .. |...|||..|.|| |. |||.|| .. HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY ------------------------------APDPRTLQRMACEVACGVLHLHRN------NFVHSDLALRNCLLTADLT-----------VKIGDYG--- .....| |.. .||| .||.. |||| ||| ||||.. ... .||.|.| DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR -----LAHCKYREDYFVTAD------------------------QLWVPLRWIAPELVDEVHSNLL--VVDQTKSGNVWSLGVTIWELFELG-TQPYPQH || |..|. .... . ..|.|| ||| ... . | |||.||..||.| .| ...|... QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM SD---------QQVLAYTVREQQL----------KLPKPQLQLTLS-------------DRWYEVMQFCWLQ-PEQRPTAEEVHLLL |. |.|. | .|...| ....|| .. . . .|..|| || ||.||| ...| | SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL |
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Kinase | LMR1.AA | TyrKc | 125-395 | 30 | 5.8e-61 | 209.77 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 125-395 Range on HMM: 1-280/280 Sequence Identity: 30% (94 aa) LLYLKEIGRGWFGKVFLGEVNSGISSAQVVVKELQASASVQEQMQFLEEVQPYRAL--KHSNLLQCLAQCAEV-------TPYLLVMEFCPLGDLKGYLR . .|..|.| ||.|..|. . || || |...| .. |..| . . | .| |...... | . |...|||..|.|||| ||| ITLGKKLGEGAFGEVYKGTWK-----IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR SCRVAESMAPDPRTLQRMACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKIGDYGLAHCKYRE-------DYFVTAD--QLW--VPLRWIAPELVDE ..| ...| .. .||| .||..|..| ||| ||||.....||||.| ||. | . || ... . .|.|| ||| KHRPK----LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-- VHSNLLVVDQTKSGN---VWSLGVTIWELFELGTQPYPQ-----HSDQQVLAYTVREQQLKLPKP-----QLQLTLSDRWYEVMQFCWLQ-PEQRPTAEE . | ||| ||..||.| .| |||| |.|.|..| . .. |. . .| |..|. || ||.||| .| --------NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF--VCCPDEMYQIMKQCWHEDPEDRPTFSE VHLLL .| .. IHECF |
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Kinase | LMR1.AA | UTK | 125-395 | 27 | 3.3e-60 | 204.65 | In-house | 1-296 (296) | Show / Hide |
Range on Protein: 125-395 Range on HMM: 1-296/296 Sequence Identity: 27% (83 aa) LLYLKEIGRGWFGKVFLGEVNSGI---SSAQVVVKELQASASVQEQM----QFLEEVQ---PYRALK-HSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGY . ....|.| || |...... ..| ||..|..|. | .. .|.|| . . ... | |.|. .. | | ..|.|... ||| | VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY LRSCRV---AESMAPDPRTLQRMACEVACGVLHLHRNNFVHSDLALRNCLLTAD-------LTVKIGDYG---LAHCKYR--------ED-YFVTADQLW ||..| |. . . ... || .|.|. .||. .||| ||| ||||.... ...||.|.| ... .. |. |. ..| LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR VPLRWIAPELVDEVHSNLLVVDQTKSGNVWSLGVTIWELFELGTQPYPQHSDQQVLAYTVREQQLKLPKPQLQLTLSDRWYEVMQFCWLQ-PEQRPTAEE .|.|| ||| ... . | . |||.||. ||.. | .||| .|..||.. .. . .|.|. ... |..|. || . |. ||..|. WPIRWMAPEALTHHT------RFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPW---DCPHPVYRLMHRCWHYDPQERPDFED VHLLL . . LVQQM |
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Kinase | LMR1.AA | TK-Unique | 125-347 | 33 | 3.5e-55 | 188.73 | In-house | 1-249 (294) | Show / Hide |
Range on Protein: 125-347 Range on HMM: 1-249/294 Sequence Identity: 33% (85 aa) LLYLKEIGRGWFGKVFLGEVNSGI--SSAQ--VVVKELQASASVQEQMQFLEEVQPYRALK-HSNLLQCLAQCAEVT-PYLLVMEFCPLGDLKGYLRSCR | ...||.| || |. ||| ... ...| |.|| |...|. .....|| | | ...|. | |..||| .| . . | ...||.|| |.| .|||.|| LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR VA--------------ESMAPDPRT--LQ-----RMACEVACGVLHLHR--NNFVHSDLALRNCLLTADLTVKIGDYGLA-HCKYREDYFVTADQLWVPL | ..| ..||| .. . |...||| .|.. ..|| ||. ||.||| |...||.|.|.| . ...| . | .|. PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI RWIAPELVDEVHSNLLVVDQTK---SGNVWSLGVTIWELFELGTQPYPQHSDQQVL || ||| . ... ..|||.||..||.| || .|||. .. ... RWMAPESLKCY-------HGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIM |
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Kinase | LMR1.AA | InsR | 125-397 | 33 | 1.4e-48 | 161.26 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 125-397 Range on HMM: 1-278/278 Sequence Identity: 33% (97 aa) LLYLKEIGRGWFGKVFLG---EVNSGISSA--QVVVKELQASASVQEQMQFLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSCRV . ..| | | ||.| .| . .. .. .. .| ....||. | || | . .. . | | . | . |||. .|||| |||| | IVLIRECGQGSFGMVYEGIAKGIVPDEEWRFGRCAIKTVNENASMRERIEFLNEASVMKEFNCHHVVRLLGVCSRGQPMYVVMEMMTYGDLKSYLRSRRP AES-----MA-----PDPRTLQRMACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKIGDYGLAHCKYREDYFVTADQLWVPLRWIAPE-LVDEVHSN | . | . . || |.. | | ..||| ||| |||. .|.|||||| |.. | || | || ||| | | | EEEFNNPGCNRNQHVPCLDQMHQMAAEICDGMAYLAAKKFVHRDLACRNCMVNHDFTVKIGDFGMTRDIYEHDYYRKGGKGMLPVRWMAPESLKDGVF-- LLVVDQTKSGNVWSLGVTIWELFELGTQPYPQHSDQQVLAYT-VREQQLKLPKPQLQLTLSDRWYEVMQFCW-LQPEQRPTAEEVHLLLSY .|.| |||.|| .|| || ||| | ||| | |. | ...|.|.|. || || |||. .. .| -----TTHS-DVWSFGVVLWEMVTLGEQPYQGLSNEQVLKYIGMDGNVLRPPE-----NCPEYWQELMMMCWQYQPKMRPTFLDIIHYLCD |
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Kinase | LMR1.AA | Pkinase_Tyr | 125-300 | 32 | 2.1e-48 | 164.56 | Pfam | 1-184 (270) | Show / Hide |
Range on Protein: 125-300 Range on HMM: 1-184/270 Sequence Identity: 32% (60 aa) LLYLKEIGRGWFGKVFLGEVN--SGISSAQVVVKELQASASVQE--QMQFLEEVQPYRAL-KHSNLLQCLAQCA-EVTP--YLLVMEFCPLGDLKGYLRS . .|..|.| ||.|..|. . . .| || | .|. .. . |..|.. . | .| |...... | . | ...|||..|.|||. |||. ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK CRVAESMAPDPRTLQRMACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKIGDYGLAHCKYREDYF-VTADQLWVPLRWIAPE | . .... .| |. ..|.| .|...|..| ||| ||||.| ...|||.| ||| | .|| .... .| .| ||| HR-EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPE |
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Kinase | LMR1.AA | RTKB | 129-395 | 32 | 3e-45 | 150.48 | In-house | 5-264 (264) | Show / Hide |
Range on Protein: 129-395 Range on HMM: 5-264/264 Sequence Identity: 32% (90 aa) KEIGRGWFGKVFLGEVNSGISS-AQVV-VKELQASASVQEQMQFLEEVQPYRAL-KHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSCRVAESMAP .. | | || ||.. | . .| . .| | ..|| |. .|..|. .| | |.. . | .||.| |.| || | ||| || .. . EKLGNGAFGEVFQAWVRNRHMNTEQSCAAKVLKPGASYEERQDFCSEMTVMKELGWHPNVIGIIGHCLQDEPYILLVELCELGNLRDYLRMCRASQHNPQ --DPRTLQRMACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKIGDYGLAHCKYREDYFVTADQLWVPLRWIAPELVDEVHSNLLVVDQTKSGNVWSL . | .. .||| .||..| .|.||. || |.. .|. || |.|.| |.|. |.. | | .| |||. . . |||| |||. SLKQAQLVDFCHQIACGMAFLHQHNVIHRDLCARNVLVDQQLHCKICDFGMAREIDHECYETTCTRL--PIKWMAPESWAHRIYT------TKSGDVWSF GVTIWELFELGTQPYPQHSDQQVLAYTVREQQLKLPKPQLQLTLSDRWYEVMQFCW-LQPEQRPTAEEVHLLL ||| || | || ||.|.. ... . | ||||.. . ...|| || . ...||. .|. .. GVTMWEIFSLGGTPYQQYRNGDIFYWL--ESGHRLPKPRQ---MPQAADHIMQMCWQMEAQHRPDFDELVDAF |
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Kinase | LMR1.AA | Trk | 125-395 | 29 | 1.1e-38 | 128.74 | In-house | 1-275 (275) | Show / Hide |
Range on Protein: 125-395 Range on HMM: 1-275/275 Sequence Identity: 29% (85 aa) LLYLKEIGRGWFGKVFLGEVNSGISSAQ---VVVKELQASASVQEQMQFLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRS-CRVA . .|.| | ||||||.| | || | ||.. | | . |.| . . | . | |.| |. |||. |||. .| IVLKWELGEGAFGKVFLAECYNLCPEQDKMMVAVKTLKD-ASENARKDFQREAELLTNLQHQHIVKFYGVCTDHDPLLMVFEYMKHGDLNKYLRQHGPDA ESMAPDPR----------TLQRMACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKIGDYGLAHCKYR-EDYFVTADQLWVPLRWIAPELVDEVHSNL . .| . . | ..| | . ||| |.| |||| ..| |||||.|. | ||. . | ||. || . MCYAQYQPRQAPGPLTIDQMLWIAKQIASGMVYMASQHFVHRDMATRNCLVGQNLIVKIGDFGMSRDVYSHTDYYRVGHHTMLPIRWMPPESI------- LVVDQTKSGNVWSLGVTIWELFELGTQPYPQHSDQQVLAYTVREQQ-LKLPKPQLQLTLSDRWYEVMQFCW-LQPEQRPTAEEVHLLL . | |||.||..|| |. | ||. | | . | .. .. |. |. . |..| || .|.|| .. ..| .. MYRKFTYESDVWSFGVVMWECFTYGKQPWYQLSNHEVIECIHQGRHRLERPR-----RCPQEVYDIMLGCWQREPQQRMNIKDIHDII |
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Kinase | LMR1.AA | TKL | 131-395 | 19 | 1.1e-37 | 131.55 | In-house | 1-364 (364) | Show / Hide |
Range on Protein: 131-395 Range on HMM: 1-364/364 Sequence Identity: 19% (72 aa) IGRGWFGKVFLGEVN-------SGISSAQVVVKELQASASVQEQM-------------------------QFLEEVQPY-RALKHSNLLQCLAQCAEVTP ||.| ||.|. |. . | .. |.|| . . . . .|.||. . |.| |..|... | . .. IGSGGFGEVYKGKWRGWGGKCPS-DTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPC -------------YLLVMEFCPLGDLKGYLRSCRVAESMAPDPRTLQRMACEVACGVLHLHRNN--------FVHSDLALRNCLLTADLT---------- . .|||.|| |.| || . . |.| ..|.|. .|| .| .| || .|.|. ..| GCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPN ----VKIGDYGLAHCKYREDYFVT----------------ADQLWV-PLRWIAPELVDEV----------HSNLLVVDQTKSGNVWSLGVTIWELFELGT .||.|.||. .. .. . . .|| |||. .. . . ... |.| |. .||.. . ADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDE-FCKGFEYSEKCDVYSFGIVLWEILTRCR QPYP-QHSDQQVLA-------YTVREQQLKLPKP---------QLQLTLSDRWYEVMQFCWLQ-PEQRPTAEEVHLLL || ......... . | . .|..| | . . ... . || || . ||.||...|. | -PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL |
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Kinase | LMR1.AA | Axl | 125-393 | 28 | 3.1e-34 | 118.56 | In-house | 1-267 (267) | Show / Hide |
Range on Protein: 125-393 Range on HMM: 1-267/267 Sequence Identity: 28% (81 aa) LLYLKEIGRGWFGKVFLGEVNSGI-SSAQVVVKELQASASVQEQM-QFLEEVQPYRALKHSNLLQCLAQCAEVTP------YLLVMEFCPLGDLKGYLRS . | .|.| || | |... |. .| || ... . | .. .|| | . .| | .. . | .. . .. | ||| .| FVLGKMLGEGEFGSVMEGQLKQEDGSFVKVAVKMMKIDICTQSEIEEFLSEAACMKEFDHPNVMRLIGVCIQMSERQRIPKPMVILPFMKHGDLHTFLLY CRVAESMAPDP-RTLQRMACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKIGDYGLAHCKYREDYFVTADQLWVPLRWIAPE-LVDEVHSNLLVVDQ |. . | .| . ..|||. | ||.| ||| |||.| |.|| . |.||.. | ||. .| .||| | | |.| SRLGDQPFYLPLQMLVKFMVDIACGMEYLSNRNFIHRDLAARNCMLREDMTVCVADFGLSKKIYSGDYYRQGCIAKMPVKWIAIESLADRVY-------- TKSGNVWSLGVTIWELFELGTQPYPQHSDQQVLAYTVREQQLKLPKPQLQLTLSDRWYEVMQFCW-LQPEQRPTAEEVHL | ||. |||.||. | ||| . . | .. . || |. . | |..| || ..|..||. .. . TSKSDVWAFGVTMWEIMTRGQTPYPGVENHEMYDYLIHGHRLKQPEDCM-----DELYDLMYQCWEADPKDRPSFSVLRE |
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Kinase | LMR1.AA | S_TKc | 125-398 | 20 | 1.1e-30 | 109.23 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 125-398 Range on HMM: 1-231/231 Sequence Identity: 20% (57 aa) LLYLKEIGRGWFGKVFLGEVNSGISSAQVVVKELQASASVQEQMQFLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPL--GDLKGYLRSCRVAES |..||.| ||||... .. . .| .|.. ... |.| . .| |. ... . . . . .|||.|. |||. |..... YEILRKIGKGAFGKVYKCRHKK--TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL -MAPDPRTLQRMACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKIGDYGLAHCKYREDYFVTADQLWVPLRWIAPELVDEVHSNLLVVDQTK-SGNV .. . ........|.. ..|.....| || | ||. ..||.| ||| . . . . ..|||.. .| . . RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL----------GYGKCKCDW WSLGVTIWELFELGTQPYPQHSDQQVLAYTVREQQLKLPKPQLQLTLSDRWYEVMQFCWL-QPEQRPTAEEVHL------LLSYL ||.|....|.. | |.| ..|.. .. |. . .. |. ||.|||| |. . .. WSCGCILYEMLC-GYPPFP---QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | LMR1.AA | Musk | 233-395 | 32 | 1.1e-29 | 95.15 | In-house | 131-282 (282) | Show / Hide |
Range on Protein: 233-395 Range on HMM: 131-282/282 Sequence Identity: 32% (54 aa) MACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKIGDYGLAHCKYREDYFVTADQLWVPLRWIAPELVDEVHSNLLVVDQTKSGNVWSLGVTIWELFE || ..||| . | ||| ||| |||| ||| |.||.. | .||.. . .| ||..|| .. | ||. || ||.| MAKQIACGMAYLSEMMFVHRDLATRNCLINEHMDVKIADFGLSRYIYHQDYYKGHENDHIPIRWMPPE-------SIWYNQFTYESDVWAYGVCLWEIFS LGTQPYPQHSDQQVLAYTVREQQLKLPKPQLQLTLSDRWYEVMQFCW-LQPEQRPTAEEVHLLL . ||| . |. |. | | | |..| || .| || ..| . YALQPYYGMTHEEVIYYIRQGNILSCPENCPQ-----KVYQLMRRCWQKNPADRPFFCQIHHCI |
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Kinase | LMR1.AA | Pkinase | 125-391 | 19 | 1.8e-22 | 80.57 | Pfam | 1-287 (293) | Show / Hide |
Range on Protein: 125-391 Range on HMM: 1-287/293 Sequence Identity: 19% (59 aa) LLYLKEIGRGWFGKVFLG-EVNSGISSAQVVVKELQASASVQEQ-MQFLE--EVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLG----DLKGYLR- . .. ||.| ||.|... ....|. .|.||.. . .. .. . |.| . |.| | .... . . . . .|||.|. | ||. |.. YHIGRKIGSGSFGCVYKCHHKGTGK---IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST --SCRV--AESMAPDPRTLQRMACEVACGVLHLHRNNFVHSDLALRNCLLTADLTV----KIGDYGLAHCKYREDYFVTADQLWVPLRWIAPELVDEVHS .... | ....... ....|. ..|.....| || . |.|. . .. ||.| ||| ... . . .. . . ....|||. WRHGCFYFSE------WECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEV------ NLL-VVDQTKSGNVWSLGVTIWELFELGTQPYPQHS------DQQVLAYTVREQQLKLPKPQLQLTL----------------SDRWYEVMQFCW-LQPE .. . ... .||.|....|.. | |.| .. ||... . ... .|. . |.. |. ... |. . |. -IRGGQYYGPKVDMWSCGCILYEMLC-GRPPFP-GHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPK QRPTAEEV .|||||.. KRPTAEQI |
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Kinase | LMR1.AA | Pkinase_Tyr | 320-395 | 38 | 7e-16 | 54.41 | Pfam | 197-270 (270) | Show / Hide |
Range on Protein: 320-395 Range on HMM: 197-270/270 Sequence Identity: 38% (31 aa) VWSLGVTIWELFELGTQP-YPQHSDQQVLAYT-VREQQLKLPK--PQLQLTLSDRWYEVMQFCW-LQPEQRPTAEEVHLLL ||| ||..||.| .| || || |...|..| . .... |. | | |..|. || .||.||| .|.| | VWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCP-------DEIYDLMKQCWHYDPEDRPTFSEIHEQL |
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Kinase | LMR1.AA | Musk | 125-217 | 33 | 5.5e-09 | 25.59 | In-house | 1-96 (282) | Show / Hide |
Range on Protein: 125-217 Range on HMM: 1-96/282 Sequence Identity: 33% (32 aa) LLYLKEIGRGWFGKVFLG---EVNSGISSAQVVVKELQASASVQEQMQFLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSC | ..|| | || || . | || | . || | || | | . | | . | |. | | .|. ||| .|.|| IIYVRDIGEGAFGRVFQARAPGLVPYEEETMVAVKMLKDDASKQMQMDFQREACMMAEFDHPNIVKLLGVCFVGRPMCLLFEYMAYGDLNEFLHSC |
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Kinase | LMR1.AA | TK-Unique | 368-395 | 34 | 0.052359 | 2.86 | In-house | 266-294 (294) | Show / Hide |
Range on Protein: 368-395 Range on HMM: 266-294/294 Sequence Identity: 34% (10 aa) SDRWYEVMQFCW-LQPEQRPTAEEVHLLL |.. |..|. || . ||.||. ... | SHEMYNLMKSCWQWEPEERPSFRQIKHRL |