Gene YANK2 (Human)

YANK2

Species: Human
Alias: STK32B, STK32, STKG6, HSA250839, YANK2
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP , GeneCards
Annotation: Consensus chromosomal location: 4p16,

Classification

Group: AGC
Family: YANK

Sequence

Name Sequence Type Origin Length Description Download
YANK2.NA RNA Sugen Kinome 3224 None Fasta, JSON
YANK2.AA Protein Sugen Kinome 414 None Fasta, JSON
YANK2.kin_dom Protein Kinase Domain Sugen Kinome 261 None Fasta, JSON

Protein domain

Protein domains of YANK2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase YANK2.AA YANK 23-283 82 2.9e-237 794.5 In-house 1-261 (261) Show / Hide 
Range on Protein: 23-283
Range on HMM: 1-261/261
Sequence Identity: 82% (215 aa)

FQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNKQKCIERDEVRNVFRELQIMQGLEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFTEGT
||||||||||||||||||||||||||||||||||||||||||||||||||||||..|||||||||||||||||||||.||||||||||||||||||.|.|
FQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNKQKCIERDEVRNVFRELQIMQKMEHPFLVNLWYSFQDEEDMFMVCDLLLGGDLRYHLQQNVHFSEDT

VKLYICELALALEYLQRYHIIHRDIKPDNILLDEHGHVHITDFNIATVVKGAERASSMAGTKPYMAPEVFQVYMDRGPGYSYPVDWWSLGITAYELLRGW
|||||||...||||||..|||||||||||||||||||||||||||||..|...||.||.|||||||||.||.|||...||||||||||||..|||.||||
VKLYICEMCMALEYLQEMHIIHRDIKPDNILLDEHGHVHITDFNIATMLKDNQRATSMSGTKPYMAPEIFQCYMDECKGYSYPVDWWSLGVCAYEMLRGW

RPYEIHSVTPIDEILNMFKVERVHYSSTWCKGMVALLRKLLTKDPESRVSSLHDIQSVPYL
|||.||| |||.||..||....|||.|.||..||.|||||||.|||.|.|||.|||..||.
RPYHIHSNTPIEEIYHMFSTNSVHYPSHWCQEMVDLLRKLLTVDPEHRISSLQDIQKHPYM
Kinase YANK2.AA AGC 23-283 25 9.3e-141 366.44 In-house 1-395 (395) Show / Hide 
Range on Protein: 23-283
Range on HMM: 1-395/395
Sequence Identity: 25% (102 aa)

FQILRAIGKGSFGKVCIVQKR------DTKKMYAMKYMNKQK-CIERD--EVRNVFRE------------LQIMQGLE----------HPFLVN-LWYSF
|..|. |||||||||. |.|.      ||.|.|||| ..|..  ....  .|... .|             .|.. .           |||.|. |.|||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QDEED--MFMVVDLLL---------GG-DLRYHLQ---QNVHFTEGTVKLYICE-------LALALEYLQR-YHIIHRD-IKPDNILLDEHGHVHITDFN
||..    ..| ...          || .| .|||   .. .|.| ... |..|       ..|||||| .  .||||| .||.||||||.||...||| 
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

IATVVK---------------------------------------------------GAERASSMAG--TKPYMAPEVFQVYMDRGPGYSYPVDWWS--L
 .....                                                   . .|.... |  |  |||||..         |....||||  |
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL---------YGKACDWWSFGL

GITAYELLRGWRPYEIH-------------SVTPIDEILNMFKVERVHYS----------STWCKGMVALLRKLLTKDPESRVSS---------LHDIQS
|.  ||.| |. |.  .              .    .. ..|. ..|..           . . .  . |..|||.|||| |  .           .|..
GCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKN

VPYL
 |. 
HPWF
Kinase YANK2.AA S_TKc 23-283 31 7.3e-84 285.83 SMART 1-231 (231) Show / Hide 
Range on Protein: 23-283
Range on HMM: 1-231/231
Sequence Identity: 31% (86 aa)

FQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNKQKCIERDEVRNVFRELQIMQGLEHPFLVNLWYSFQDEEDMFMVVDLLLG--GDLRYHLQQNVH---
..||| ||||.||||. .....|.. .|.| ..          ... ||.||..   ||..|.| ..||| ....|| ... |  |||. ..... .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FTEGTVKLYICELALALEYLQRYHIIHRDIKPDNILLDEHGHVHITDFNIATVVKGAERASSMAGTKPYMAPEVFQVYMDRGPGYSY-PVDWWSLGI
   |.| ... |......||||. . .|||||.||.||||||  |. |.|| .|...      ... ||  ||||||.        ||.. ..||||.|.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL--------GYGKCKCDWWSCGC

TAYELLRGWRPYEIHSVTPIDEILNMFKVERVHYSSTWCKGMVALLRKLLTKDPESRVSSLHDIQ------SVPYL
. ||.| |  |..      ....... .           . .  ..||.|.|||| | .     |      . |..
ILYEMLCGYPPFP-----QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase YANK2.AA SGK 23-283 33 9.7e-81 248.97 In-house 1-283 (283) Show / Hide 
Range on Protein: 23-283
Range on HMM: 1-283/283
Sequence Identity: 33% (99 aa)

FQILRAIGKGSFGKVCIVQKRDT------------------KKMYAMKYMNKQKCI-------ERDEVRNVFREL-QIMQGLEHPFLVNLWYSFQDEEDM
|..|  |||||||||  |.. |.                  .|.||||  .||  |        . |....  |   |.. . |||.||| |.|| ..  
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

FMVVDLLLGGDLRYHLQQNVHFTEGTVKLYICELALALEYLQRYHIIHRDIKPDNILLDEHGHVHITDFNIAT-VVKGAERASSMAGTKPYMAPEVFQVY
..| | . ||.. ||||   || |  .. |  |...|||||    ||.|| ||.|||||  ||. .|||  .   .|  .  .. .||  |.||||    
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVL---

MDRGPGYSYPVDWWSLGITAYELLRGWRPYEIHSVTPI-DEILNMFKVERVHYSSTWCKGMVALLRKLLTKDPESRVSSL---HDIQSVPYL
  |. ...  ||||.||.  ||.. |  |..   .    | |.|  .  . .. |  ..    |.  ||.|||. |  .     .|.. |. 
--RKQPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQ-PLQIPPQMSNDAW---DLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase YANK2.AA Akt 23-225 41 1.7e-72 231.04 In-house 1-203 (264) Show / Hide 
Range on Protein: 23-225
Range on HMM: 1-203/264
Sequence Identity: 41% (86 aa)

FQILRAIGKGSFGKVCIVQKRDTKKMY-AMKYMNKQKCIERDEVRNVFRELQIMQGLEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFTEG
|..|. .||||||||  |.| ||.|.| |||   |...|....|.... |  | |   |||.||| ||||...  ..| |   ||.| ||||.   |.| 
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

TVKLYICELALALEYLQRYHIIHRD-IKPDNILLDEHGHVHITDFNIAT--VVKGAERASSMAGTKPYMAPEVFQVYMDRGPGYSYPVDWWS-LGITAYE
. . |..|. ||.|.|    || ||  || |||.|..||. .|||  .   ..|  ... .. ||  |.|||. .     | |.. .||||. ||.  ||
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILN-----GNGHTKAVDWWGSLGCVMYE

LLRGWRPY
.. |. |.
MMCGRPPF
Kinase YANK2.AA Pkinase 23-283 28 3.4e-70 244.32 Pfam 1-293 (293) Show / Hide 
Range on Protein: 23-283
Range on HMM: 1-293/293
Sequence Identity: 28% (85 aa)

FQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNKQKCIERDEVRNVF-RELQIMQGLEHPFLVNLWYSFQDEEDMFMVVDLLLGG----DLRYHLQ--QN
..|.| ||.||||.|.. ....| |..|.| ..|..  .  .....  .|.|||. | ||. | |...|.|. .. || ... ||    ||  ...  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

VHF--TEGTVKLYICELALALEYLQRYHIIHRDIKPDNILLDEHGHV----HITDFNIATV--VKGAERASSMAGTKPYMAPEVFQVYMDRGPGYSYPVD
  |  .| ..| |. ... .|||. .  |||||.||.|||.|..||.    .|.|| .| .      . ... .|| .|||||| .     |..|...||
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR----GGQYYGPKVD

WWSLGITAYELLRGWRPYEIH--SVTPIDEILNMFKVERVHYSSTWC-----------------------KGMVALLRKLLTKDPESRVSSLHDIQSVPY
.||.|.. ||.| |  |.  |  . . .|..  .... .  ... |                        . .  .....|.|||..| .  ..|   |.
MWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-AEQILQHPW

L
.
F
Kinase YANK2.AA RSK 26-283 31 1e-69 237.9 In-house 1-278 (278) Show / Hide 
Range on Protein: 26-283
Range on HMM: 1-278/278
Sequence Identity: 31% (88 aa)

LRAIGKGSFGKVCIVQKR---DTKKMYAMKYMNKQKCIERDE-VRNVFRELQIMQGLE-HPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVH---
|.  |.|..||| ...|    ||.. ||||  .| | . |.  .| ...| .|..  . |||.|.| |.||.|.  ... ... ||.| .|||. .|   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FTEGTVKLYICELALALEYLQRYHIIHRDIKPDNILLDE---HGHVHITDFNIATV-VKG-AERASSMAGTKPYMAPEVFQVYMDRGPGYSYPVDWWSLG
|.| ... |. |..||.|.|   .|||||.||.|||.|.   .||. .|||  .   .    ... .  .|  |||||.  .   .. |..  .||||||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRAN-QQGGHDKACDWWSLG

ITAYELLRGWRPYEIHSVT-PIDEILNMFKVER--VHYS--STWCKGMVALLRKLLTKDPESRVSS----LHDIQSVPYL
.  ||.| | .|.   .     .||..  .  .  .     ..  . .  |.||.|..||. | ..    . .|.. |..
VLMYEMLTGCPPFQG-PNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase YANK2.AA RSK-Unclassified 23-225 38 1.7e-67 210.87 In-house 1-222 (283) Show / Hide 
Range on Protein: 23-225
Range on HMM: 1-222/283
Sequence Identity: 38% (87 aa)

FQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNKQKCIERDEVRNVFRELQIMQGLEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQ--QNVHFTE
|   | ||.|.||||  |.|.||...|||| ..|.| | .  .. |  |  ||   .||| | | .||| .  .... .   |||.  |||      |.|
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE

GTVKLYICELALALEYLQRYHIIHRDIKPDNILLDEHGHVHITDFN--IAT--------------------VVKGAERASSMAGTKPYMAPEVFQVYMDR
  |. |. |  .||||| .  .| || |||||.|.  |||  |||   |                      ..    |. |  ||  |.|||.      |
DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMI-----R

GPGYSYPVDWWSLGITAYELLRGWRPY
. |    |||| |||  ||.| |  ||
RCGHTKAVDWWTLGIVMYEMLFGCPPY
Kinase YANK2.AA AktR 23-221 43 6.6e-65 221.94 In-house 1-201 (268) Show / Hide 
Range on Protein: 23-221
Range on HMM: 1-201/268
Sequence Identity: 43% (89 aa)

FQILRAIGKGSFGKVCIVQKR-DTKKMYAMKYMNKQKCIERDEVRNVFRELQIMQ-GLEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFTE
|.... .||| ||||  |||. |..|.||||   |.| |||   . . .| .||.    |||.|.| |.||..|  | . .   ||.| .||... .|.|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

GTVKLYICELALALEYL-QRYHIIHRDIKPDNILLDEHGHVHITDFNIAT--VVK-GAERASSMAGTKPYMAPEVFQVYMDRGPGYSYPVDWWSLGITAY
 ... |...  |||||| |...|| ||.||.||||||.||| ||||  .   ...   |.| |  ||  |||||. .       |. ..||||..||  |
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKK----KGHNKSVDWWAFGIFIY

ELLRG
|.. |
EMVTG
Kinase YANK2.AA PKA 23-234 37 5.1e-60 205.72 In-house 1-208 (263) Show / Hide 
Range on Protein: 23-234
Range on HMM: 1-208/263
Sequence Identity: 37% (81 aa)

FQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNKQKCIERDEVRNVFRELQIMQGLEHPFLVN-LWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFTEG
|.|.. .|.||||.|. ........ |||| ..||. . .  |  |  | .|.| ..|||.|. ....|||.   .|| ..  ||.. ..|. . .|.. 
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

TVKLYIC-ELALALEYLQRYHIIHRDIKPDNILLDEHGHVHITDFNIATVVKGAERASSMAGTKPYMAPEVFQVYMDRGP-GYSYPVDWWSLGITAYELL
. |.|.. .  ||||||   .||.|| || |||.|. ||. ||||  |  |..  | ... ||  |.|||. |     .  |.  .||||.|||  ||.|
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD--RTWTLCGTPEYLAPEIIQ-----SKNGHGKSVDWWALGILIYEML

RGWRPYEIHSVTPID
 |  | . |  .|..
AGYPPFYDHNRDPMQ
Kinase YANK2.AA Delta 23-283 35 8.3e-60 205.0 In-house 1-259 (259) Show / Hide 
Range on Protein: 23-283
Range on HMM: 1-259/259
Sequence Identity: 35% (96 aa)

FQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNKQKCIERDEVRNVFRELQIMQ-GLEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFTEG
|.... .|||||||| ..  ....| ||.| . |.  .| |.|   . | ...  . |||||  |. .|| .| .| |.. | |||| ||.||  .| | 
FHFHKVLGKGSFGKVMLAELKGKNKYYAIKCLKKDVVLEDDDVECTMVERRVLALAWEHPFLCHLFCTFQTKEHLFFVMEYLNGGDLMYHIQQCHRFDEK

TVKLYICELALALEYLQRYHIIHRDIKPDNILLDEHGHVHITDFNIA-TVVKGAERASSMAGTKPYMAPEVFQVYMDRGPGYSYPVDWWSLGITAYELLR
  . | ||. ..|..| .  || ||.| ||.|||  ||..| || .. . . | ..||.  ||  |.|||. .     |  |.  ||||| |.  ||.| 
RARFYACEIICGLQFLHKKGIIYRDLKLDNVLLDCDGHIKIADFGMCKENMYGEKKASTFCGTPDYIAPEIIK-----GQKYNHSVDWWSFGVLMYEMLI

GWRPYEIHSVTPIDEILNMFKVERVHYSSTWCKGMVALLRKLLTKDPESRVSS----LHDIQSVPYL
|  |.. .     ||. .   ..| .|  .  |    .|.||. .||| |. .      ||.  .. 
GQSPFHGEDE---DELFWSICNDRPWYPRWITKEAKDCLKKLFERDPEKRLGVQYCPKGDIRQHCFF
Kinase YANK2.AA Ciliate-E2 23-283 21 4.7e-59 201.34 In-house 1-365 (365) Show / Hide 
Range on Protein: 23-283
Range on HMM: 1-365/365
Sequence Identity: 21% (80 aa)

FQILRAIGKGSFGKVCIVQKRDTKKM-----------------------YAMKYMNKQKCIERDEVRNVF----------RELQIMQGLEHPFLVNLWYS
. ... ||.|.||.|. .... ..|.                       ||||.|.|.. ..   . ...           |..|.. | ||..... ..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FQ--DEEDMFMVVDLLLGGDLRYHL-------------------QQNVHFTEGTVK-------LYICELALALEYLQRYH-IIHRDIKPDNILLDEHGHV
||  |.. ...| ... ||||....                   ..  ....  ..        ||... ||||||   . ||||||||.|||.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

HITDFNIATVVKGA--------------------------------ERASSMAGTKPYMAPEVFQ-VYMD---RGPGYSYPVDWWSLGITAYELLRGWRP
 |.|| ... ..                                  . . . .|| .|||||...    |    . ||.| .|.||||.. ||.| | .|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

YEIHSVTPIDEILN-MFKVERVHYSSTWCKGMV---------------ALLRK----LLTKDPESRVSSLHDIQSVPYL
.       ...|..  ..    .. .   . ..                |..|    .| |||| | ..  .|   |..
F-------QQQIKQCKIDFPCPEWQKD-TQ-CIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase YANK2.AA Pkinase_Tyr 23-219 24 2.7e-14 49.02 Pfam 1-208 (270) Show / Hide 
Range on Protein: 23-219
Range on HMM: 1-208/270
Sequence Identity: 24% (53 aa)

FQILRAIGKGSFGKVCIVQKR----DTKKMYAMKYMNKQKCIERD-EVRNVFRELQIMQGL-EHPFLVNLWYSFQ-DEED--MFMVVDLLLGGDLRYHLQ
 .... .|.|.||.|.    .    .||   | | . |... ...   .  .||..||  |  || .|.|      ..|   ...|. .  .|||. .|.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

Q----NVHFTEGTVKLYICELALALEYLQRYHIIHRDIKPDNILLDEHGHVHITDFNIATVVKGAERA-SSMAGTK---PYMAPEVFQVYMDRGPGYSYP
.    . ..|  .   .  . | ..||| . ..||||.   |.|..| ..| |.||  |  .   .    .  |.|   . ||||... .      ..  
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK-----FTTK

VDWWSLGITAYELL
 | || |.. .|..
SDVWSFGVLMWEIF
Kinase YANK2.AA TyrKc 23-280 20 6.9e-14 1.82 SMART 1-280 (280) Show / Hide 
Range on Protein: 23-280
Range on HMM: 1-280/280
Sequence Identity: 20% (59 aa)

FQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNKQKCIERDEVRNVFRELQIMQGL--EHPFLVNLWYSFQDE-------EDMFMVVDLLLGGDLRYHLQ
 . .. .| | ||.|.  . .    . | | ... .      ..   ||..||  |  .|| .|.|     ..       | ...|. .  .|||. .|.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

QNVH-FTEGTVKLYICELALALEYLQRYHIIHRDIKPDNILLDEHGHVHITDFNIATVVKGA-------ERASSMA--GTKP-----YMAPEVFQVYMDR
 . . ..  .   .    |   ||| . ..||||.   |.|..| ..| |.||  .  ..         .  ...   |.|       ||||... ..  
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK--

GPGYSYPVDWWSLGITAYELL-RGWRPYEI---HSVTPIDEILNMFKVE-RVHYSST--------WCKGMVALLRKLLTKDPESRVSSLHDIQSV
   ..   | || |.. .|.. .|  ||.    . . . .|...  |   |                . |  . ..    |||.| .    ..  
---FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase YANK2.AA Akt 258-283 30 0.0112 4.29 In-house 235-264 (264) Show / Hide 
Range on Protein: 258-283
Range on HMM: 235-264/264
Sequence Identity: 30% (9 aa)

LLRKLLTKDPESRVS----SLHDIQSVPYL
|...||.|||. |       ...|.. |..
LISGLLNKDPKKRLGGGPNDAQEIKRHPWF