Gene YSK1 (Human)

YSK1

Species: Human
Alias: DKFZp686J1430, STK25, YSK1, SOK1
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP , GeneCards
Annotation: Consensus chromosomal location: 2q37.3,

Classification

Group: STE
Family: STE20
Subfamily: YSK

Sequence

Name Sequence Type Origin Length Description Download
YSK1.NA RNA Sugen Kinome 2198 None Fasta, JSON
YSK1.AA Protein Sugen Kinome 426 None Fasta, JSON
YSK1.kin_dom Protein Kinase Domain Sugen Kinome 251 None Fasta, JSON

Protein domain

Protein domains of YSK1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase YSK1.AA YSK 20-270 81 8.4e-242 736.45 In-house 1-257 (257) Show / Hide 
Range on Protein: 20-270
Range on HMM: 1-257/257
Sequence Identity: 81% (209 aa)

FTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSALDLLKP---GPLEETY
|||...||.||||||||||||.|..||||||||||.||||||||||||..||||||||||.|.|||||.|||||||||.||||.|||.||   |...|.|
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIEDIQQEIQFLSQCDSPYITKYYGSYLKDTKLWIIMEYCGGGSCLDLMKPKYVGQFDEKY

IATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQ--SAYDFKADIWSLGITAIELAKGEPP
||.|||||||||||||||||||||||||||||||.|||||.|||||||.||||||||||||||.|||||||.|  |.||||||||||||||.|.||||||
IAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNTFVGTPYWMAPEVICQEVSYYDFKADIWSLGITAYEMAKGEPP

NSDLHPMRVLFLIPKNSPPTLEG-QHSKPFKEFVEACLNKDPRFRPTAKELLKHKFI
..|.|||||.|||||| ||.||| ..||.||||||.||||||..||.||||||||||
YCDYHPMRVMFLIPKNNPPKLEGRSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase YSK1.AA STE20 20-270 53 2.8e-170 572.0 In-house 1-288 (288) Show / Hide 
Range on Protein: 20-270
Range on HMM: 1-288/288
Sequence Identity: 53% (153 aa)

FTKLDRIGKGSFGEVYKGIDNHTKEV----VAIKIIDLEEAE---DEIEDIQQEITVLSQCDSPYITRYFGSYLKS----TKLWIIMEYLGGGSALDLLK
...|..||.||.|.|||.....|.|.    ||||...||...   ||.||||.|| ...||..|.|..|.|||||.    ..|||.|||.||||..|..|
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

-----PG-----PLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTD----TQI-KRNTFVGTPFWMAPEVIKQ----
      .     |..| .||.|.||.|.|||||||...|||||||.|.||.|.|.||||||||..|||.    |.  |||||||||.|||||||..    
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGP

-SAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIP--KNSPPTLEG----QHSKPFKEFVEACLNKDPRFRPTAKELLKHKFI
 . ||.|.|||||||||||.|.||||..|.||||..|.||  .| ||||..    . |. |..||. ||.||| .||||..||||.||
DKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase YSK1.AA MST 20-270 53 1.8e-145 465.4 In-house 1-254 (254) Show / Hide 
Range on Protein: 20-270
Range on HMM: 1-254/254
Sequence Identity: 53% (137 aa)

FTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYFGSYL--KSTKLWIIMEYLGGGSALDLLK--PGPLEET
|......| ||.| ||| |.  |...||||..  .|    ...|  ||. ..||.|.|| .|.|||.  | . .||.||| |.||..|. |    .| | 
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPVNE---DLQEIIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMKITQRTLNEQ

YIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPN
 ||.||.  |.||.|||. .||||||||.| ||.. |  |||||||.||||||. ||||..|||.||||||| .. || |||||||||||||.| |.|| 
QIACILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMAKRNTVIGTPYWMAPEVIQEIKYDCKADIWSLGITAIEMAEGMPPY

SDLHPMRVLFLIPKNSPPTLE--GQHSKPFKEFVEACLNKDPRFRPTAKELLKHKFI
||.||||..|.||.. |||.    | |  |  ||  || |.|  |.||..||.| ||
SDIHPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase YSK1.AA STE 20-270 38 5.5e-141 474.69 In-house 1-359 (359) Show / Hide 
Range on Protein: 20-270
Range on HMM: 1-359/359
Sequence Identity: 38% (141 aa)

FTKLDRIGKGSFGEVYKGIDN------HTKEV---------VAIKIIDLEEAE----------------DEIEDIQQEITVLSQCD--SPYITRYFGSYL
......||||.||.|||....      .|.||         .|||...||. .                .|...|..|| ....|.  .|.| .|.|.|.
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

KS-------TKLWIIMEYLGGGSALDLLK-------P--------GPLEETYIATILREILKG-LDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAG
|        ..|||.|||..|||. |..|       |        ....|. ||.|.|.|||| |.|||| ..||||||.||.||     |||.||||.|
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

QLTD---------------TQI-KRNTFVGTPFWMAPEVIKQ------SAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKN-----------
||||               |.  ||||||||| |||||||.|      . ||.|.||||||.|.||.| |.|| .|.||||..|.||.|           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----SPPTLEG-------------------QHSKPFKEFVEACLNKDPRFRPTAKELLK--HKFI
     ||.|.                    . |..||.|.. ||.|||. ||||..|||  |.||
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase YSK1.AA FRAY 20-270 44 4.6e-113 352.59 In-house 1-277 (277) Show / Hide 
Range on Protein: 20-270
Range on HMM: 1-277/277
Sequence Identity: 44% (123 aa)

FTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAE-DEIEDIQQEITVLSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSALDLLK-------P--
.   . ||.|  . |.| .    .| .|||.|.||  .   ....  || . .||  | .  |. |..    ||..| ||..|| ||..|       |  
YELQEVIGEGATAVVHKAYCIPRQENCAIKRINLEKCQNTSMDELIKEIQAMCQCHHPNVVHYHTSFVVNEELWLVMRYLECGSCLDIMKFKMPQGEPHK

-GPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTD-----TQIKRNTFVGTPFWMAPEVIKQSA-YDFKADIWSLG
 | ..|  |||||.|.||||.|.|.  .||||||| |.|. | | . .||||| . | .     ..  | |||||| ||||||. |   |||||||||.|
QGVFDEHVIATILKEVLKGLCYFHKNGQIHRDIKAGNILIGEDGTIQIADFGVSAWLATGGDLSRCCVRHTFVGTPCWMAPEVMEQVHGYDFKADIWSFG

ITAIELAKGEPPNSDLHPMRVLFLIPKNSPPTLEGQ---------HSKPFKEFVEACLNKDPRFRPTAKELLKHKFI
|||||||.| .|  .. || || |.  | ||.||.           .. ||. .| || |||. |||| ||||||| 
ITAIELATGKAPYHKYPPMKVLMLTLQNDPPSLETDEDDKDMYKKYGHSFKKMIEKCLQKDPSKRPTASELLKHKFF
Kinase YSK1.AA KHS 20-270 52 1.4e-105 356.13 In-house 1-258 (258) Show / Hide 
Range on Protein: 20-270
Range on HMM: 1-258/258
Sequence Identity: 52% (135 aa)

FTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSALDLLK-PGPLEETYIA
.  | |.| | .|.|||  | ...|..|.|.| . |..|... |||||... .|  | |  ||||||.  ||||.||| ||||  |. .  |||.|  ||
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKM-EPGDDFAVIQQEIMMMKDCRHPNIVAYFGSYLRRDKLWICMEYCGGGSLQDIYHVTGPLSELQIA

TILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI---KQSAYDFKADIWSLGITAIELAKGEPPN
 . ||.|.||.||||. |.||||| ||.||..|||||||||||..|.| |  ||  |.|||.||||||    ..  |.   |||..||||||||   || 
YVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWAVGITAIELAELQPPM

SDLHPMRVLFLIPKNS--PPTLEGQH--SKPFKEFVEACLNKDPRFRPTAKELLKHKFI
 ||||||.|||. | .  ||.|. .|  |. | .||  .| |.|. ||||. ||.|.|.
FDLHPMRALFLMTKSNFQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase YSK1.AA PAKA 20-270 42 1.1e-104 354.12 In-house 1-260 (260) Show / Hide 
Range on Protein: 20-270
Range on HMM: 1-260/260
Sequence Identity: 42% (111 aa)

FTKLDRIGKGSFGEVYKGIDNHTKEV--VAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSALDLLKPGP------
..... ||.|. ||||.... .|..   |||| ..... .. .| |  || |. .|  . | .|  ||| . .||..|||..||.  |...         
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKN-QPKKELIINEILVMKECKHKNIVNYIDSYLVDDELWVVMEYMEGGCLTDVITQCCNIQCNY

LEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKG
..|  || ..||.|.||...||.  ||||||  |.||  .|.||..||| . |||. | |||| |||| |||||||..  || | ||||||| |||.. |
MDEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRKQYDEKVDIWSLGIMAIEMIEG

EPPNSDLHPMRVLFLIPKN-SPPTLEGQH-SKPFKEFVEACLNKDPRFRPTAKELLKHKFI
|||  .  | | ..|| .|  |. ..    |. |..|...||..|.. |..|.|||.| |.
EPPYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase YSK1.AA S_TKc 20-270 33 2e-100 340.84 SMART 1-231 (231) Show / Hide 
Range on Protein: 20-270
Range on HMM: 1-231/231
Sequence Identity: 33% (90 aa)

FTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYFGSYLKSTKLWIIMEYLGG--GSALDLLKPGP------
...|. ||||.||.|||.....|...||||||.        |.|..|| .|.. . |.| ......   ..|...|||..|  |. .|..|  .      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDF-KADIWSLGITAIELA
 . |  .. ....|...|.|.|| . ||||.| .|.||.|   .|..|||.| ||       .||.|||..|||||.    |.. |.|.||.|.. .|..
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

KGEPPNSDLHPMRVLFLIPKNSPPTLEGQHSKPFKEFVEACLNKDPRFRPTAKELLK-------HKFI
 |.|| .  ...... .|            |...|.|.. ||.|||. |||| |.|.       | ..
CGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase YSK1.AA PAKL 20-270 46 6.4e-100 338.27 In-house 1-256 (256) Show / Hide 
Range on Protein: 20-270
Range on HMM: 1-256/256
Sequence Identity: 46% (120 aa)

FTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYFGSYLKS-TKLWIIMEYLGGGSALDLLK--PGPLEETY
|      | ||.| |||.|   |  . ||| | . |.  ||.||. || .|  | .|.|  ||||     ...|| |.|   ||  |...     |.|  
FEFQEKLGQGSYGSVYKAIHKDTNFPLAIKVIEIKESN-EIKDIEKEIQILKKCKCPNIVSYFGSIQQKLNHYWILMDYCSLGSINDMMESCCKTLNEKQ

IATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQI-KRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPN
|. ||.  |||| ||||   |||||||||.||.| ..||.|||||  || |.     |  .|||.|||||.|..  |. |.|||||||||||.| |.||.
ISVILQQTLKGLHYLHSKNIIHRDIKAANILLNEDCQVKIADFGVSQQLQDEYDGQANQMIGTPYWMAPEIINKQNYNNKCDIWSLGITAIEMADGFPPH

SDLHPMRVLFLIPKNSPPTLEG--QHSKPFKEFVEACLNKDPRFRPTAKELLKHKFI
.|. ||| .  ||   |||.      |. |  |.  |. |||  |. . .|| | ||
YDMPPMRAMYMIPNWPPPTFSNPKHWSPCFNDFLAQCCVKDPEKRWSPIDLLCHPFI
Kinase YSK1.AA MSN 20-270 47 4.9e-93 307.55 In-house 1-265 (265) Show / Hide 
Range on Protein: 20-270
Range on HMM: 1-265/265
Sequence Identity: 47% (127 aa)

FTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQ-CDSPYITRYFGSYLK------STKLWIIMEYLGGGSALDLLK---P
|   . .|.| .|.||||.   | ...|||..|..|  || |.|.||| .| .      |  |.| ..|        .||..||. | ||  ||.|    
FELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVRE--DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGHDHQLWMVMEFCGAGSVTDLVKMTKG

GPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIK-----QSAYDFKADIWSLGIT
  | | .|| | ||||.|| .||... ||||||  |||| .. .||| ||||. ||  |  .||||.|||.|||||||.     . .||...|.||.|||
QSLKEDWIAYICREILRGLAHLHQHKVIHRDIKGQNVLLTHNAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSVGIT

AIELAKGEPPNSDLHPMRVLFLIPKNSPPTLEGQH-SKPFKEFVEACLNKDPRFRPTAKELLKHKFI
|||.| |.||  |.|||| |||||.|.||.|  .  || |..|.| || |.  .||.....||| ||
AIEMAEGQPPLCDMHPMRALFLIPRNPPPKLKSKKWSKKFHNFMEKCLIKNYHQRPYTEQMLKHPFI
Kinase YSK1.AA Pkinase 20-270 29 1.1e-92 319.03 Pfam 1-293 (293) Show / Hide 
Range on Protein: 20-270
Range on HMM: 1-293/293
Sequence Identity: 29% (86 aa)

FTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQ---EITVLSQCDSPYITRYFGSYLKSTKLWIIMEYLGGG----SALDLLK---P
.... .||.||||.|||...  | ..||.|||........ . .     || ..  ...|.| |.....  .......|||..||    .  |...    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GPL--EETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDV----KLADFGVAGQL-TDTQIKRNTFVGTPFWMAPEVIK-QSAYDFKADIWSL
|..  .|  .  ....||.||.|.||.. ||||.| .|.|....|..    |..|||.| |. .  .   .||.|||..||||||. .. |. |.|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GITAIELAKGEPPNSDL----HPMRVLFLIPKNSPPTLEGQHS-----------------------KPFKEFVEACLNKDPRFRPTAKELLKHKFI
|.. .|.. |.|| ..     . .. ...| .. .| |. . .                       ...|.|.. ||.|||  ||||...|.|...
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase YSK1.AA Ste20-DD1 20-270 43 2.4e-87 296.47 In-house 1-268 (268) Show / Hide 
Range on Protein: 20-270
Range on HMM: 1-268/268
Sequence Identity: 43% (117 aa)

FTKLDRIGKGSFGEVYKG-------IDNHTKEVVAIKIIDLEE-AEDEIEDIQQEITVLSQC-DSPYITRYFGSYLKSTKLWIIMEYLGGGSALDLLK--
|  .  || |||| |          ..    .|.|.| . ..     |      ||..|    | ||| .| | |.|.  | |.|||  ||| || ..  
FQIVEVIGQGSFGVVCTCRWMKKKDRNTNNNRVIACKFVEMNADDVEENSNLKKEIDILKNTMDCPYIVKYHGCYIKENMLMIVMEYCDGGSILDIMQMC

PGPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQ----SAYDFKADIWSLGIT
   | |  || |.  | ||| |||| | .|||||| |||. . |  |||||||   .  .  | || .| |.||.||.|        || ||||||||||
SKRLIEEQIAAICYQIVKGLVYLHSNRITHRDIKAGNVLVNKEGQPKLADFGVSTIAVNQGFKMNTVIGSPYWMSPEIIMPPKGSQGYDQKADIWSLGIT

AIELAKGEPPNSDLHPMRVLFLIPKNSPPTLE--GQHSKPFKEFVEACLNKDPRFRPTAKELLKHKFI
|||.|   ||  .. | || | ||   ||||.  .  |  |  |.  |||..|  || | .|| | ||
AIEMAESKPPRFNVNPVRVIFVIPHQQPPTLKIPSNWSPEFNDFIKQCLNMNPDKRPSAQQLLNHPFI
Kinase YSK1.AA Pkinase_Tyr 20-204 34 8.4e-33 111.72 Pfam 1-203 (270) Show / Hide 
Range on Protein: 20-204
Range on HMM: 1-203/270
Sequence Identity: 34% (70 aa)

FTKLDRIGKGSFGEVYKGIDN----HTKEVVAIKIIDLEEAEDE---IEDIQQEITVLSQC-DSPYITRYFGSYL-KSTK--LWIIMEYLGGGSALDLLK
 |..  .|.|.|||||||. .     ||  ||.|..  | | .|   .||  .|. ...|  . | | |. |  . ..    ..|.|||  .|. || |.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

-----PGPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQL--TDTQ-IKRNTFVGTPFWMAPEVIKQSAYDFKADIWS
     ..||    .  . ..| ||..||.| . ||||. | |.|..|.. || .||| |  .  .|.   ||       .|||||.|. . .  | |.||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWS

LGIT
 |..
FGVL
Kinase YSK1.AA TyrKc 20-270 26 2.8e-29 104.51 SMART 1-280 (280) Show / Hide 
Range on Protein: 20-270
Range on HMM: 1-280/280
Sequence Identity: 26% (76 aa)

FTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQC--DSPYITRYFGSYLKS-------TKLWIIMEYLGGGSALDLL-KP
 |... .| | |||||||. .   . ||.| .  .     .||. .|. ....   . | | | .|  ...         |.|.|||  .|. .| | |.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

GP-LEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDT-------QIKRNTF-VGTP-----FWMAPEVIKQSAYDFK
.| |       .   | .| .|||| . ||||. | |.|..|.. || .||| .  ..|        . .| .   |.       |||||.|. . . .|
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTK

ADIWSLGITAIELA-KGEPPNSD-----LHPMRVLFLIPKNSPPTLEGQ--------HSKPFKEFVEACLNKDPRFRPTAKELLKHKFI
 |.|| |..  |.   |..| ..     . . .|. .. .   .              ..   .  . | . ||  ||| .|.  |...
SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase YSK1.AA Pkinase_Tyr 250-270 38 2.28225 1.87 Pfam 252-270 (270) Show / Hide 
Range on Protein: 250-270
Range on HMM: 252-270/270
Sequence Identity: 38% (8 aa)

CLNKDPRFRPTAKELLKHKFI
| ..||  ||| .|.  | ..
CWHYDPEDRPTFSEI--HEQL