Gene DokA (Slime mold)

DokA

Species: Slime mold
Alias: DokA, DdisK276, DDB0185194
External Links: DictyBase Link ,
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
DokA.AA Protein None 1671 None Fasta, JSON
DokA.kin_dom Protein Kinase Domain None 8 None Fasta, JSON

Protein domain

Protein domains of DokA.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PAS DokA.AA PAS 712-779 19 0.005533 16.03 SMART 1-68 (68) Show / Hide 
Range on Protein: 712-779
Range on HMM: 1-68/68
Sequence Identity: 19% (14 aa)

ENLSFLLKSTPIIIWRADHNGEMVFFKKSDEIPI--DEKKVVGNNFQDFLQWVPQTYR--TNFQEMFQNSLK
|... .| ..| .||. ||.|.....  . .      .. ..|.   .... ..  .|    ||| .|....
ERYRAILENMPDGIWVWDHDGRITYWNPAACQMFGYSPEELIGQ---SWWDLIHPEDRNLERFQE-HQRLQQ
PAS DokA.AA PAS 917-985 23 3.1e-05 24.65 SMART 1-68 (68) Show / Hide 
Range on Protein: 917-985
Range on HMM: 1-68/68
Sequence Identity: 23% (17 aa)

ETYNILFKLSLLGVMFSTFKGIILDANDMLLQTIGYTRGDLENGKIDWMLLTPPEHF--EISARALQELKA
| |. ..  .  |..  . .| |...|.. .|  ||.. .|     .|  | .||..  |   . .|.| .
ERYRAILENMPDGIWVWDHDGRITYWNPAACQMFGYSPEELIGQ--SWWDLIHPEDRNLERFQE-HQRLQQ
HisKA DokA.AA HisKA 1043-1108 34 1.1e-24 89.3 SMART 1-89 (89) Show / Hide 
Range on Protein: 1043-1108
Range on HMM: 1-89/89
Sequence Identity: 34% (31 aa)

LKTQFITNISHELRTPCHGIVGMSQLLLD----------SQLTNTQ-------------RDNIDSIKRSTDSLISLINDILDFSKLEYG
 |.||. |.||||||| ..| |...||.|          . |.  |             |. ...|.|..|.. .||||.||.|..| |
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
HisKA DokA.AA HisKA 1043-1108 44 2.5e-24 87.76 Pfam 1-69 (69) Show / Hide 
Range on Protein: 1043-1108
Range on HMM: 1-69/69
Sequence Identity: 44% (31 aa)

LKTQFITNISHELRTPCHGIVGMSQLLLD-SQLTNTQ--RDNIDSIKRSTDSLISLINDILDFSKLEYG
 |.||. |.||||||| ..| |...||.| . |.  |  |. ...|.|..... .||||.||||..| |
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
HATPase_c DokA.AA HATPase_c 1157-1276 33 6.7e-40 139.79 SMART 1-130 (130) Show / Hide 
Range on Protein: 1157-1276
Range on HMM: 1-130/130
Sequence Identity: 33% (50 aa)

GDRNSLKKVLLNLVGNAVKFTETGF------------VLLEISTDYESGDQISLRFTVKDSGIGIPE------NKIEQIFVPFGQIDG--------SFSR
||.. |. ||.||..||.|.|..|.              .... .         |.||.|.|.|||.       .|..|| ||.. |.        | ||
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH---------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSR

KYGG--SGLGLSFCKELVALMGGYIRVESGDQEGGKGTTFWFAIKVSI
||||  .||||| ||..| ..|| |.||         |||.| .....
KYGGGLTGLGLSICKRIVEQHGGTIWVE---------TTFTFTLPLER
HATPase_c DokA.AA HATPase_c 1157-1275 39 2.1e-37 132.41 Pfam 1-120 (120) Show / Hide 
Range on Protein: 1157-1275
Range on HMM: 1-120/120
Sequence Identity: 39% (51 aa)

GDRNSLKKVLLNLVGNAVKFTET-GFVLLEISTDYESGDQISLRFTVKDSGIGIPE------NKIEQIFVPFGQIDG-SFSRKYGG--SGLGLSFCKELV
||.. |. |..|||.||.|.|.. | . .....|        .|.||.|.|.|||.       .|..|| ||.. |. |  |||||  .||||. |...|
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-----DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSR-RKYGGGLTGLGLYICRRIV

ALMGGYIRVESGDQEGGKGTTFWFAIKVS
 ..|| |.|||     |.||||.| ... 
EQHGGTIWVESEP---GGGTTFTFTLPLE
Kinase DokA.AA HisK 1157-1275 25 8.1e-26 89.75 In-house 1-164 (164) Show / Hide 
Range on Protein: 1157-1275
Range on HMM: 1-164/164
Sequence Identity: 25% (43 aa)

GDRNSLKKVLLNLVGNAVKFTETG------FVLLEISTDY-------------ESGDQ---------ISLRFTVKDSGIGIPENKIEQIFVPFGQIDG--
 | | .| .|.||..||.|||. |      .. .... .              ..  .           ....|.|.|.|.||.....|| .||.||.  
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

----------SFSRKYGGSGLGLSFCKELVALMG--------GYIRVESGDQEGGKGTTFWFAIKVS
          . . .  | ||||. |. |. ..|        . | |.|   | |||.||.| |   
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQS---EVGKGSTFSFYIYNN
Response_reg DokA.AA Response_reg 1315-1367 18 2.185615 3.95 Pfam 1-50 (115) Show / Hide 
Range on Protein: 1315-1367
Range on HMM: 1-50/115
Sequence Identity: 18% (10 aa)

VLIIESNQMVIMSIQSILL-SMKC-ECISASKAITALDLLESSKSTENQIDIIVC
|||.. .. . . .. ||  .. . .. .|. .  ||....  .     .|.|..
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH-----PDLIIM
REC DokA.AA REC 1518-1629 23 6.8e-31 109.88 SMART 1-150 (150) Show / Hide 
Range on Protein: 1518-1629
Range on HMM: 1-150/150
Sequence Identity: 23% (38 aa)

KYILVAEDN----DINIKVVV------RQLEKLGYT--------AIVGINGL-------KALEIIGSF-------------PICLILLDCQMP-------
. ||...|.     .. ...       | |||.||.        ...  .|         |||.. ..             |. ||..|..||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

QMDGFTCSTILRQIEPTGQRIPIIAMTANDS---KDRCFEVGMDDYLSKPVRVDRLQKTL
 |||..    .|         |||..||.|.   . |..|.|.|||..||.. ..|....
GMDGIELCRRIR---------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg DokA.AA Response_reg 1520-1630 28 1.8e-23 86.65 Pfam 1-115 (115) Show / Hide 
Range on Protein: 1520-1630
Range on HMM: 1-115/115
Sequence Identity: 28% (34 aa)

ILVAEDNDINIKVVVRQLE-KLGY-TAIVGINGLKALEIIGSFPICLILLDCQMPQMDGFTCSTIL-RQIE-PTGQRIPIIAMTANDS---KDRCFEVGM
.|...|.... ..... || | ||  . .  .|  |||..    . ||..|..|| |||..  . . || . |.   .|||..||...   . .....|.
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHHPDLIIMDINMPGMDGLELCRRIRRQHPHPQ---TPIIMCTAHGDEDDAVEALQAGA

DDYLSKPVRVDRLQKTLS
.||..||.  |.| . . 
NDYITKPFDPDELHAAIR