Gene Rio1 (Slime mold)
Rio1
Sequence
Protein domains of Rio1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | Rio1.AA | RIO1 | 163-384 | 60 | 3e-150 | 505.46 | In-house | 1-225 (225) | Show / Hide |
Range on Protein: 163-384 Range on HMM: 1-225/225 Sequence Identity: 60% (136 aa) QVLDPRTRLMLFKMINKGAFSEINGCISTGKEANVYHAFTPNEE--ERAVKVYKTSILVFKDRDRYVTGEFRFRRGYSKHNPRKMVKVWAEKEFRNLTRL ||.|||||..||||. .| |||||||||||.||||| . | . |.|.|.|||||||||||..|| ||||||.|..|||||||.|.|||||.||| |. QVIDPRTRMILFKMLTRGIITEINGCISTGKETNVYHASETNGKRAEYAIKIYKTSILVFKDREKYVDGEFRFRHGHCKHNPRKMIKIWAEKEMRNLKRI KNAGIPCPTPLILRNHILVMTFIGKDGYAAPRLKDATVSQEKFG-VIYLDCIKMMRTLFHKCRLVHADLSEYNMLYYKNQLYIIDVSQSVEHDHPHSLDF . |||| |.......|.| |||||| |||||||. . . .|. |. ||.. |||||||||||||||. ||.|||||||||||||||.| YQSEIPCPEPIMVKSNVLMMEFIGKDGMAAPRLKDYQYKERDQYFHYYHQMIQYMRRMYQDCRLVHADLSEYNMLYHNDKLYMIDVSQSVEHDHPHSLEF LRMDCSNVTDFFRKKEVNTMFIQEL ||||| || ..|.|. | .. . .. LRMDCKNVNMYFMKHNVIIFPVRDI |
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RIO | Rio1.AA | RIO | 154-390 | 53 | 3.4e-132 | 446.4 | SMART | 1-253 (253) | Show / Hide |
Range on Protein: 154-390 Range on HMM: 1-253/253 Sequence Identity: 53% (135 aa) DKEDRATTEQVLDPRTRLMLFKMINKGAFSEIN--GCISTGKEANVYHAFT----PNEEERAVKVYKTSILVFKDRDRYVTGEFRFRRGYSKHNPRKMVK ||||.|| |.|.|||||. |.||.|.| ..||| ||||||||||||||.. .| .|.|||.|.||...||...||..|.|||. ||...|.||||. DKEDYATYEEVFDPRTRMTLYKMVNRGYIEEINNHGCISTGKEANVYHAMGGDFDKNGNECAVKIYRTSTTEFKRMWRYIQGDFRFKHGYHHINWRKMVR VWAEKEFRNLTRLKNAGIPCPTPLILRNHILVMTFIGKDGYAAPRLKDATVSQEKFGV---IYLDCIKMMRTLFHKCRLVHADLSEYNMLYY------KN .||||||||| |...||.|||.| .|.|.||| |||.||..||||||.. ... . .| . . || ..| |.||||||||||||| .. LWAEKEFRNLQRMYEAGVPCPKPIAWRRHVLVMEFIGDDGWPAPRLKDVEWEEWEMDFKWEYYWQIMEYMRKMYHECHLVHADLSEYNMLYHDLEDENDC QLYIIDVSQSVEHDHPHSLDFLRMDCSNVTDFFRKKEVNTMFI-QELFEFITD ..|||.|||||.|||..|.||..|. |...|||.| | . | |.||.||. KVWIIDWSQSVECDHPMWLEFLERDIWNIINFFRRKGVDCDDIYREIFERITG |
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Kinase | Rio1.AA | RIO | 161-398 | 36 | 1.6e-130 | 439.91 | In-house | 1-276 (276) | Show / Hide |
Range on Protein: 161-398 Range on HMM: 1-276/276 Sequence Identity: 36% (100 aa) TEQVLDPRTRLMLFKMINKGAFSEINGCISTGKEANVYHAFTPNEE-----------ERAVKVYKTSILVFKDRDRYVTGEFRFRRGYSKHNPRKMVKVW ||..||.||....||.|.| ....||..|||...||. . | | |.| |...|....||||..|. |||.|. ...|||.|.|.. | YEQTNDPYTRMIMYKMVNRGMVESVGNCIGVGKESDIYHCSNENGEDEKEDSKVIPTECAIKIHRTGRTSFKDRKKYRDGEFYFKHRHCKHNWRYMHRLW AEKEFRNLTRLKNAGIPCPTPLILRNHILVMTFIGKDGYAAPRLKDATVS-QEKFGVIYLDCIKMMRTLFHKCRLVHADLSEYNMLYYKNQL-------Y ||||.||. || .|.|||.|.....|.||| ||..|. .||..... . | .|..|. ||.| . |||||.|..|.||... . . | AEKEMRNMKRLYQSGFPCPEPIDYKRHVLVMEFINHDQMPAPKYPMCQIHEHENMKHVYHQCMCYMRRLYQHCRLVHCDFNEFNMMWHDGKHDENDCGFY IIDVSQSVEHDHPHSLDFLRMDCSNVTDFFRKKEV-NTMFIQELFEFI------------------TDLTITEDNI .||..|.|||||||.|...|.|| .| .|| |. | .. |.|.| ...|....|. MIDFPQMVEHDHPHALWYFRRDCKCVNMFFMKRFVYEPFPEREMFDFVGFGDGYKYAYPDFKRDVKRTDTLDHENM |
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Kinase | Rio1.AA | RIO1 | 196-384 | 49 | 3.6e-115 | 359.65 | Pfam | 1-200 (200) | Show / Hide |
Range on Protein: 196-384 Range on HMM: 1-200/200 Sequence Identity: 49% (99 aa) NVYHAFT-PNEE-ERAVKVYKTSILVFKDRDRYVTGEFRFRRGYSKHNPRKMVKVWAEKEFRNLTRLKNAGIPCPTPLILRNHILVMTFIG-KDGYAAPR ||||| . .... |.|||.|.|....||...||. ..|||| .|..||.|.||..||||||||| |...||.||| | ...|.||| ||| |||..||| NVYHAYSMEDGKDECAVKIYRTGTTCFKKMKRYRDYDFRFRHRYHHHNWRYMVRMWAEKEFRNLKRMYEAGVPCPKPIDWNRHVLVMEFIGDKDGWPAPR LKDAT----VSQEKFGVIYLDCIK-MMRTLFHKCRLVHADLSEYNMLYYKN-QLYIIDVSQSVEHDHPHSLDFLRMDCSNVTDFFRKKEVN--TMFIQEL |||. |.|.. || ..| || . ..|.|||.||||||.|.... ..|||..|.|||||||.|.||..|| |. .|||.| |. .| . |. LKDVEMELELSEEEAEEIYDEIIREYMRRMYQECGLVHGDLSEYNILVHDDGKPWIIDWPQAVEHDHPHALEFLERDCRNIINFFRRKGVDERVMDFREI |
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Kinase | Rio1.AA | RIO3 | 158-399 | 47 | 2.5e-85 | 287.71 | In-house | 1-254 (254) | Show / Hide |
Range on Protein: 158-399 Range on HMM: 1-254/254 Sequence Identity: 47% (121 aa) RATTEQVLDPRTRLMLFKMINKGAFSEINGCISTGKEANVYHAF-TPNEEER----------AVKVYKTSILVFKDRDRYVTGEFRFRRGYSKHNPRKMV .|.|. .||.|||...||.| | . | |||.||||. |.||. |.|. |.||.||.. ||.||.|. .|||. .|| ||||. HSTAEKAVDPKTRLLMYKMVNSGMLETITGCIATGKESVVFHAYGGSMEDEKEDSKVIPTICAIKVFKTTLNEFKNRDKYIKDDFRFKDRFSKLNPRKIH KVWAEKEFRNLTRLKNAGIPCPTPLILRNHILVMTFIGKDGYAAPRLKDATVSQEKFGVIYLDCIKMMRTLFHKCRLVHADLSEYNMLYYKNQLYIIDVS ..||||| ||.|.. ||||||| ..|. |||||.|||.| ||.||. . |. | . ...|| |.|.| ||||||||||||.. ....|||| RMWAEKEMHNLARMQRAGIPCPTVVLLKKHILVMSFIGHDQVPAPKLKEVKLNSEEMKEAYYQTLHLMRQLYHECTLVHADLSEYNMLWHAGKVWLIDVS QSVEHDHPHSLDFLRMDCSNVTDFFRKKEV-NTMFIQELFEFITDLTITEDNID |||| ||| |.|| || ||..||.| | ... .|||. .. | || || QSVEPTHPHGLEFLFRDCRNVSQFFQKGGVKEALSERELFNAVSGLNITADNEA |