Gene Bud32 (Slime mold)
Bud32
Sequence
Protein domains of Bud32.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | Bud32.AA | Bud32 | 37-250 | 42 | 3.3e-151 | 487.29 | In-house | 1-269 (269) | Show / Hide |
Range on Protein: 37-250 Range on HMM: 1-269/269 Sequence Identity: 42% (114 aa) IG-ILIS--------QGAEAKTY-------------ETDLYGLK-------CIVKERFSKAYRHPILDQKISSKRILQEVRSLNKCKKKGIQVPSLYLVD .. |.. |||||... .|...... ||.||||.||||||.|||.....|..||||..|.|.|.||.||..|..| MSLELYKDVDIAPISQGAEARVFYTCYLTVSKQKVYTTCNFQGRAKDSHQQCIIKERFPKAYRHPQLDQQLTKHRTKQEVRAMNRCRKAGICVPYVYFCD IGNNRIYMEFI---KG----ETVKHYLYKNQES---TQHQNQIESIMKELGNQIGIIHEMNVIHGDLTTSNMLLR--ESTNE-----LVFIDFGLSYTSN ..|..||||.| .| .|||.|....||. .||........|..|.|||..|....||||||||||.|| ..... ...|||||||.|| NYNHCIYMEYIEESPGGHGFYTVKNYIWQHQETQKEDQHDQCLREFCKKVGRQIGKMHWNHIIHGDLTTSNMMLRHPYADWTKLYGQMHLIDFGLSYISN SV-EDKAVDLYVLERAFISTHPNSEQ-----LFQTILSNYELTSSN---SKIVIQKLNQVRLRGRKKTC || |||.||||||||||.||||..|| .|.....||...... .|.|..|.|.|||||||.| SVPEDKGVDLYVLERAFLSTHPKCEQKYNAWIFEHFMENYRKQDTKCKKFKAVLKKFNEVRLRGRKRTM |
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| Kinase | Bud32.AA | Dicty3 | 113-186 | 23 | 3.4e-12 | 36.36 | In-house | 80-185 (351) | Show / Hide |
Range on Protein: 113-186 Range on HMM: 80-185/351 Sequence Identity: 23% (25 aa) IYMEFIKGETVKHY-----LYKNQEST-QHQNQIESIMKELGNQIGIIHEMN-VIHGDLTTSNMLLREST-------NE------------------LVF ||||.| ||. . . |... . .|..|...| . ||... .||.|... | .| |. . . IYMEYIEGEIPISFVKTNNMLKKHKNNRFNEHEISKIICDLVKTLNYIHKNCHIIHRDIKCDNIMLDNDEQHQCNNNNNKMSSTCRDIQCYYSNEINWKL IDFGLS |||||| IDFGLS |
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| Kinase | Bud32.AA | Ciliate-C3 | 112-183 | 28 | 3.2e-09 | 29.41 | In-house | 62-140 (140) | Show / Hide |
Range on Protein: 112-183 Range on HMM: 62-140/140 Sequence Identity: 28% (23 aa) RIYMEFIKGETVKHYLYKNQESTQHQNQIES--------IMKELGNQIGIIHEMNVIHGDLTTSNMLLRESTNELVFIDF .|..|. .|.|.. .. . ... ..| | . | | . | .|| |..|||. ||.|. | .|. ||| QIFLEYFEGQTLEKFINEIYDNKKYQDQNHKDLKLQKLQISKQILQAIDYLHEHNIVHGDIKFSNILI-NSKDEIKIIDF |
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| Kinase | Bud32.AA | Ciliate-E2 | 115-190 | 22 | 5.7e-09 | 26.91 | In-house | 113-207 (365) | Show / Hide |
Range on Protein: 115-190 Range on HMM: 113-207/365 Sequence Identity: 22% (23 aa) MEFIKGETVKHYLYKNQESTQHQ---------NQIESIMKELGN---------------QIGIIHEMN-VIHGDLTTSNMLLRESTNELVFIDFGLSYTS ||...| . ..|...|. . .|. ..| |||.. . . .|. | .|| |. .| |. . |||||| MEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------IKIIDFGLSKKY N . D |
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| Kinase | Bud32.AA | Ciliate-E1 | 127-200 | 22 | 3.5e-08 | 23.22 | In-house | 98-172 (202) | Show / Hide |
Range on Protein: 127-200 Range on HMM: 98-172/202 Sequence Identity: 22% (17 aa) LYKNQESTQHQNQIESIMKELGNQIGIIHEMNVIHGDLTTSNMLLRESTNELVFIDFGLSY--TSNSVEDKAVDLY ...... .. |...|.. | .. ..| .|.||.|. .| | . ...|. |||.| .|. ... .. | QCQQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQ-GNYVYCDFGISKFLKNNQNQQCQYKGY |
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| Kinase | Bud32.AA | FNIPK | 113-191 | 25 | 5e-08 | 22.4 | In-house | 90-180 (425) | Show / Hide |
Range on Protein: 113-191 Range on HMM: 90-180/425 Sequence Identity: 25% (23 aa) IYMEFIKGETVKHY-----LYKNQE-STQHQNQIESIMKELGNQIGIIHEMN--VIHGDLTTSNMLLRESTNELVFIDFGLS----YTSNS ||||.| | . | | |.. . . |...| .| . |||.. .||.|. . | .. . .|...| | | . IYMEYIDGYIPISYVKTNNLLKKHPHNQFPEDIISRCMCDLVKSLNCIHENGRHIIHRDIKCDNIMIVNDEFHSCDFDYNCSKDISYYSKD |
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| S_TKc | Bud32.AA | S_TKc | 35-251 | 17 | 3.8e-07 | -72.15 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 35-251 Range on HMM: 1-231/231 Sequence Identity: 17% (46 aa) DEIGILISQGAEAKTYETDLYG--LKCIVKERFSKAYRHPILDQKISSKRILQEVRSLNKCKKKGIQVPSLYLVDIGNNRIY--MEFIKG--ETVKHYLY ||. .| .|| .| | . .. .|. ..|..|.. | | . . || | ...| ||.. | ....|. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------------EHIRREIQILKK---HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIK KNQE----STQHQNQIESIMKELGNQIGIIHEMNVIHGDLTTSNMLLRESTNELVFIDFGLSYTSNSVE--------------DK-AVD----------L |.. . . .. ..|... . . .|....|| || .| || | .. .||||. . .| ..| . KRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL-TTFCGTPWYMAPEVLGYGKCKCDWWSCGCILYEM YVLERAFISTHPNSEQLFQTILSNYELTSSNSKIVIQKLNQVRLR------GRK-------KTCF .. . | . ...|. |. |. | |.|. |. . . | LCGYPPFP----QMQMMFKKIG------SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF |
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| Kinase | Bud32.AA | Ciliate-E3 | 115-186 | 32 | 2e-06 | 16.63 | In-house | 83-153 (202) | Show / Hide |
Range on Protein: 115-186 Range on HMM: 83-153/202 Sequence Identity: 32% (24 aa) MEFIKGETVKHYLYKNQESTQHQNQIESIMKELGNQIGIIHEMNVIHGDLTTSNMLLRESTNELV--FIDFGLS .|. ..||. |. || | | |.... . .||| |.||.|. .| |. .. | |. . |||.| QEYCSNGDLYHYIK-QQNKTQ--NIIYDICIQIIQGMIAIHEKNIIHSDIKPDNILVDKNNNQLIIKICDFGES |
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| Kinase | Bud32.AA | TKL | 155-186 | 28 | 1.5e-05 | 15.97 | In-house | 149-201 (364) | Show / Hide |
Range on Protein: 155-186 Range on HMM: 149-201/364 Sequence Identity: 28% (15 aa) HEMN--------VIHGDLTTSNMLLRESTNE-------------LVFIDFGLS | || .|| ||...| |. | . . ||||| HSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLS |
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| Kinase | Bud32.AA | LISK | 155-185 | 41 | 1.7e-05 | 13.61 | In-house | 118-151 (296) | Show / Hide |
Range on Protein: 155-185 Range on HMM: 118-151/296 Sequence Identity: 41% (14 aa) HEMNVIHGDLTTSNMLLRES---TNELVFIDFGL |.||.|| ||. | |.||. .. . .|||. HSMNIIHRDLKSKNCLVRENDNNQWRIKVCDFGF |
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| Kinase | Bud32.AA | VRK | 154-187 | 33 | 1.9e-05 | 13.87 | In-house | 146-181 (284) | Show / Hide |
Range on Protein: 154-187 Range on HMM: 146-181/284 Sequence Identity: 33% (12 aa) IHEMNVIHGDLTTSNMLLRES--TNELVFIDFGLSY .||.. |||.. .| || .. . . .|.||.| LHENEYVHGDIKAANILLGFEKNPDQVYLVDYGLAY |
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