Gene IrlC (Slime mold)

IrlC

Species: Slime mold
Alias: IrlC, DDB0231222, DdisK094
External Links: DictyBase Link ,
Annotation:

Classification

Group: Other
Family: IRE

Sequence

Name Sequence Type Origin Length Description Download
IrlC.AA Protein None 1444 None Fasta, JSON
IrlC.kin_dom Protein Kinase Domain None 268 None Fasta, JSON

Protein domain

Protein domains of IrlC.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SWIM_MAP3K1 IrlC.AA SWIM_MAP3K1 506-547 31 2.2e-08 27.52 In-house 21-64 (77) Show / Hide 
Range on Protein: 506-547
Range on HMM: 21-64/77
Sequence Identity: 31% (14 aa)

TCSCEDYK--REFSCKHMFFILLNYYHVPRNSYLIYQRQFTEIE
||.| |.   |   |||  .... .. ||| .. ..|.  |. |
TCTCPDCQKHRGNHCKHICWVMMRVFQVPRDHPWWWQKGLTQTE
Kinase IrlC.AA IRE 984-1246 52 3.3e-173 581.72 In-house 1-292 (292) Show / Hide 
Range on Protein: 984-1246
Range on HMM: 1-292/292
Sequence Identity: 52% (154 aa)

ENVLGRGSNGTLVFKGIWNNRIPVAIKQMQKMFNPLISKEIEVLITLTNKNCYNIVRYIDQEEDESCVYLGLTLCDGSLQNLVEK-GDNNLTLTQFLGYD
.|.||||.|||||||||||.|||||.|||||.|||.||.||..||.|...|..|..||..||||. .|||.|.||.||||..||.  .||.. ...  ..
NNILGRGCNGTLVFKGIWNGRIPVAVKQMQKEFNPFISREIQMLIKLESDNHPNVIRYYCQEEDDQFVYLALELCQGSLQDYVEQKKRNNFINSSNNSNN

INSSSKNNS-------RLLELIKDIVYGIQFLHQQGIVHNDLNPRNILIKDDR---------FIISDLGLSKMEVTSSYSFTMHA---PTGQEGFHPAEV
 |....||.       |...|||....|.|.||.|.|||.||.|.||||...|         |.|||.||.||.|...||||...   |||..|.||.|.
NNKNNNNNNNQWQIHIRMWQLIKQCMNGLQHLHSQNIVHRDLKPHNILIHMNRPNQHGENNRFMISDFGLCKMLVEGRYSFTRNIRSGPTGTWGWHPPEM

LLE---KRKTKSVDIFSMGCILFYLMTGGQHPFG-DKFYRIVNILTDKPILEPLK-HNLVA----CDLISQMISKNESDRPTIEKILLHPFF
|.|   ||||||||||||||...|.||.|||||| ||..|..|||..|..|..|| ||...    ||||.|||......||||...| ||||
LQEFCQKRKTKSVDIFSMGCVFYYVMTNGQHPFGNDKLHRQANILKGKYNLDQLKHHNHWHIVIACDLIHQMIHHDPQKRPTIKECLNHPFF
Kinase IrlC.AA Ciliate-E2 981-1246 19 2.6e-35 118.66 In-house 1-365 (365) Show / Hide 
Range on Protein: 981-1246
Range on HMM: 1-365/365
Sequence Identity: 19% (72 aa)

RKEENVLGRGSNGTLVFKGIWNNRI-----------------------PVAIKQMQKMFNPLISKEIEVLITLT-------------NKNCYNIVRYIDQ
 |  ...|.|. |.      |...                         .|.|.|.|     |..|| .. ..              . |. ||..... 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

EE--DESCVYLGLTLCDG-SLQNLVE----KGDNNLTLTQFLGYDINSSSKNNSRLLE--------LIKDIVYGIQFLHQQG-IVHNDLNPRNILIKDDR
 .  |....|| . .|.| .|. . .    | .....  . . ....  ..    .|.         |  |. ....||... |.| |. | |||.    
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEK-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

FIISDLGLSK-----------------------MEVTSSYS------FTMHAPTGQEGFHPAEVLL---------EKRKTKSVDIFSMGCILFYLMTGGQ
  |.|.||||                       ...|..|.      .. .   |  |. . |.|          .|. ....||.|.|.||.....| .
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG-K

HPFGDKFYRIVNILTDKPILE-----------------PLKHNLVACDLISQ----MISKNESDRPT-IEKILLHPFF
.||      . .|.  |  .                  ..|. . . |||..    |. |... |.| .|.|| ||.|
PPF------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase IrlC.AA Ciliate-E2-Unclassified 982-1246 18 1.3e-34 117.43 In-house 2-352 (352) Show / Hide 
Range on Protein: 982-1246
Range on HMM: 2-352/352
Sequence Identity: 18% (67 aa)

KEENVLGRGSNGTLVFKGIWNNR--------IPVAIKQMQKMFNPLISKEIEVLITLTNKN-------------------CYNIVRYIDQEEDESCVYLG
|   ..|.|..|. |.| . ..         . ......||  .  .  ..  .... ||.                   . .||.......|. ..|. 
KIIKQIGQGGFGK-VYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

LTLC-DGSLQNLVEKGDN----------------NLTLTQFL---GYDINSSSKNNSRLLELIKDIVYGIQFLHQQG-IVHNDLNPRNILIKDD----RF
. .| .|.|..  .|  .                 .|  | .                 . ... |. |...||... |.| |. | |||....    . 
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKA-------------KFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYI

IISDLGLSK--MEVTSSYSFT------------MHAPTGQEGFH----PAEVLLEKRKT----KSVDIFSMGCILFYLMTGGQHPFGD------------
 |.|.|.||   .   .. ..            |.  .|  ..     . ||| ..       ...||.|.|.||.....|  .||.|            
KIIDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGY-YPFYDNNCEQHQQLITQ

--------KFYRIVNIL-TDKPILEP----LKHNLVACDLIS----QMISKNESDRPTIEKILLHPFF
         .|.. .   ...|  ..     . .  | |.|.    .|. || . |.|.|.|| ||.|
WINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase IrlC.AA Pkinase 981-1246 23 3.8e-31 111.23 Pfam 1-293 (293) Show / Hide 
Range on Protein: 981-1246
Range on HMM: 1-293/293
Sequence Identity: 23% (75 aa)

RKEENVLGRGSNGTLVFKGIWNNR-IPVAIKQMQKMFNPLISK--------EIEVLITLTNKNCYNIVRYIDQEEDESCVYLGLTLCDG-----SLQNLV
 . . ..|.|| |. |.|... .  . ||.|.. |  .   .|        ||...  | |  . ||||..|  ||.. .|. . .|.|     .|  ..
YHIGRKIGSGSFGC-VYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRL-N--HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYI

EKGDNNLTLTQFLGYDINSSSKNN----SRLLELIKDIVYGIQFLHQQGIVHNDLNPRNILIKDDRFI-----ISDLGLSK-MEVTSSYSFTMHAPTGQE
.                 .....       .   .. |. |....|..||.| || | ||||...  |     |.| ||.| .. . ..|  |. ..|  
ST----------------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS--MTTFCGTP

GFHPAEVLL-EKRKTKSVDIFSMGCILFYLMTGGQHPFG--------DKFYRIVNILTDKPILEPLKHN--------------------LVACDLISQMI
.. . ||..  .  ...||..|.||||..... |. ||         |. ..|..|.  ..  .  . .                      ..|.|. ..
WYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCL

SKNESDRPTIEKILLHPFF
 |. ..|||.| || ||.|
CKDPKKRPTAEQILQHPWF
Kinase IrlC.AA S_TKc 981-1246 22 2.7e-29 104.55 SMART 1-231 (231) Show / Hide 
Range on Protein: 981-1246
Range on HMM: 1-231/231
Sequence Identity: 22% (64 aa)

RKEENVLGRGSNGTLVFKGIWNN-RIPVAIKQMQKMFNPLISKEIEVLITLTNKNCYNIVRYIDQEEDESCVYLGLTLCDG---SLQNLVEKGDNN----
 .  ...|.|. |. |.|.....    ||||..       | .||..|      .. |||...|  .| ...|. . .|||   .|  . .|   .    
YEILRKIGKGAFGK-VYKCRHKKTGRIVAIKIIK----EHIRREIQILKK----HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LTLTQFLGYDINSSSKNNSRLLELIKDIVYGIQFLHQQGIVHNDLNPRNILIKDDRFIISDLGLSKMEVTSSYSFTMHAPTGQEGFHPAEVLLEKRKTK
 ..  .                  ... |. .....|..||.| || | |||. . .  |.| ||..           .   |   . . |||     .|
PFPE-H---------------ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGK

-SVDIFSMGCILFYLMTGGQHPFGDKFYRIVNILTDKPILEPLKHNLVACDLISQMISKNESDRPTIEKILL-------HPFF
 ..|. | ||||. ... |. ||    ... ...              |.|.|...  |. ..|||. ..|        ||.|
CKCDWWSCGCILYEMLC-GYPPFP-QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase IrlC.AA CAMK 986-1246 16 5.4e-27 83.43 In-house 1-425 (425) Show / Hide 
Range on Protein: 986-1246
Range on HMM: 1-425/425
Sequence Identity: 16% (73 aa)

VLGRGSNGTLVFKGIWN-NR------------IPVAIKQMQK--MFN-----------------------------PLISKEIEVLITLTNKN----CYN
.||||| |. |...|   .               |||| . |  . .                               . .|||.. .| ...      |
TLGRGSFGK-VKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPN

IVRYIDQEED-------------------ESCVYLGL---TLCDGS------LQNLVEKGD---NNLTLTQFLGYDINSSSKNNSR--------L-----
|.. ..  ||                   ....|. .    .|.|       .. .||.|.   ..         |         .        .     
IIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEF---------D---------QFDIVERGRFTEREA

LELIKDIVYGIQFLHQQGIVHNDLNPRNILIKDD------------------RFIISDLGLSKMEVTSSYSF---------------------TMHAPTG
  ... |. .....|...||| || | |||. |.                     |.| |....   .. .|                      |. . |
RRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCG

QEGFHP-AEVLLEKR--------------KTKSVDIFSMGCILFYLMTGGQHPFGDK--------------FYRIV-NILTDKP--ILEPLKH---NLV-
  .. .  |||. |.               ....|. |.|.||. . .|   || ..               |..  .|.. |   . .....   | . 
TPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCG-YPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCN-YG

------------------ACDLISQMISKNESDRPTIEKILLHPFF
                  . |||..|  .. ..|.||| .| ||..
PEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase IrlC.AA TKL 987-1244 14 4.6e-24 83.55 In-house 1-364 (364) Show / Hide 
Range on Protein: 987-1244
Range on HMM: 1-364/364
Sequence Identity: 14% (57 aa)

LGRGSNGTLVFKGIWNN---------RIPVAIKQMQKMFNPLI---------------------------SKEIEVLITLTNKNCYNIVRYID--QEEDE
.|.|. |  |.||.|..           .||.|.. .. . .                             .|.|..  . . .. |||...   .... 
IGSGGFG-EVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPC

SC-----------VYLGLTLC-DGSLQNLVEKGDNNLTLTQFLGYDINSSSKNNSRLLELIKDIVYGIQFLHQQG--------IVHNDLNPRNILIKDD-
 |            ..   .|  ||| ...                        .... ...||  |...||...        |.| ||...|||.... 
GCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENW

--------------RFIISDLGLSK-MEVTSSYSFTMHA----------------PTGQEGFHPAEVLLEK----------------RKTKSVDIFSMGC
              .  |.|.|||. |. ... . ||..                . |  .. . ||| ..                  ....|..|.| 
TNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGI

ILFYLMTGGQHPFG-DKFYRIV---------NILTD---KPILE---------PLKHNL--VACDLISQMISKNESDRPTIEKILLHP
.|. ..|. . |.  .... ..          .  |   .| .          .  ..     ..|. .  . . ..||. ..|| . 
VLWEILTRCR-PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase IrlC.AA ULK 981-1139 22 3.1e-20 67.41 In-house 1-191 (329) Show / Hide 
Range on Protein: 981-1139
Range on HMM: 1-191/329
Sequence Identity: 22% (45 aa)

RKEENVLGRGSNGTLVFKGIWNNR-----IPVAIKQMQ---KMFNP----------LISKEIEVLITLT----NKN-CYNIVRYIDQEEDE--SCVYLGL
    ..|| || |  |.||. ...     . ||.|...   .  ..          |. .||... .|     .|| . |||...|  |.    ..|. .
YCLNHCLGKGSFG-KVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIM

TLCDG-SLQNLVEKGDNNLTLTQFLGYDINSSSKNNSR------LLELIKDIVYGIQFLHQQGIVHNDLNPRNILIKDD-------------RFIISDLG
 .|.|  |... .| ...|.... .          . .       .. .|.|. | ..||...|.| |. | ||||...             .. |.| |
EYCNGGDLEQYIKK-NKKLPEDT-E----------EKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFG

LSKM
..|.
FAKH
Kinase IrlC.AA ULK 981-1139 21 7.5e-18 59.97 In-house 1-187 (324) Show / Hide 
Range on Protein: 981-1139
Range on HMM: 1-187/324
Sequence Identity: 21% (44 aa)

RKEENVLGRGSNGTLVFKG--IWNN--RIPVAIKQMQ---KMFNP----------LISKEIEVLITLT---NKNCYNIVRYIDQEEDE--SCVYLGLTLC
    ..|| || |  |.||  . .|     ||.|...      ..          |. .||... .|    ..|. .||...|  |.     .|. . .|
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNH-HIVKLYDWFETSNHNNIYIIMEYC

DG-SLQNLVEKGDNNLTLTQFLGYDINSSSKNNSR------LLELIKDIVYGIQFLHQQGIVHNDLNPRNILIKDD-------------RFIISDLGLSK
.|  |... .| ...|.. . .          . .       .. .|.|. | ..||...|.| |. | ||||...             .. |.| |..|
NGGDLEQYIKK-NKKLPE-T-E----------EKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAK

M
.
H
Kinase IrlC.AA STE 982-1246 18 6.2e-17 56.44 In-house 1-359 (359) Show / Hide 
Range on Protein: 982-1246
Range on HMM: 1-359/359
Sequence Identity: 18% (69 aa)

KEE-NVLGRGSNGTLVFKGIWNN----------------RIPVAIKQMQ--------------------KMFNPLISKEIEVLITLTNKNCYNIVRYIDQ
 |   ..|.|. || |.|.. ..                   .|||||                     ..    | |||...  . .  . |||.|.. 
WEGIEKIGKGAFGT-VYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHM-HPNIVKYYGC

EEDE-------SCVYLGLTLCD-GSLQNLVE---KGDNNLTLTQFLGYDINSSSKNNSRLLELIKDIVYG-IQFLHQQGIVHNDLNPRNILIKDDRFIIS
...|       . ... . ..| |||  ...   .  ..|.. .       ..  . | .   ...|. |  ..||...|.| |. | |||.      ..
YFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQ----H-QHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL----VKLC

DLGLSKMEVTS--------------SYSFTMHAPTGQEGFHPAEVLLE------KRKTKSVDIFSMGCILFYLMTGGQHPFGDKFYR--IVNIL------
| |...  . |              . .      .|   .   ||..       |  . ..|| | || .  . | |..|. |  .   . .|.      
DFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMAT-GKPPWHDMHPMRAMFMIPFNYHMQ

----------TDKPILE------------------PLKHNLVACDLISQMISKNESDRPTIEKILL--HPFF
           . | |.                  | |     .| |..   |. ..||| .. |   |||.
QQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase IrlC.AA AGC 1162-1246 19 9.6e-15 33.07 In-house 277-395 (395) Show / Hide 
Range on Protein: 1162-1246
Range on HMM: 277-395/395
Sequence Identity: 19% (24 aa)

EVLLEKRKTKSVDIFS--MGCILFYLMTG-------G-----QHPFGDKFYRIVNIL------TDKPILEP---------LKHNLVACDLISQMISKNES
|.|     .|..|. |  .||... ..||             . || ...    .|.      ..|. . .          .    | |||.... |. .
EIL----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRH-PFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPE

DRPT----------IEKILLHPFF
.|..          .| |  ||.|
KRLGCGGNDFGDKGAEEIKNHPWF
Kinase IrlC.AA ULK 1162-1246 21 4.1e-13 42.2 In-house 221-329 (329) Show / Hide 
Range on Protein: 1162-1246
Range on HMM: 221-329/329
Sequence Identity: 21% (24 aa)

EVLLEK--RKTKS---VDIFSMGCILFYLMTGGQHPFGDKFYRIV-----NILTDKPIL------EPLKHN---------LVACDLISQMISKNESDRPT
..| ..  .|  .   .||.|.|||.... .|   ...  |.  .     . . ..| .      .||. .             |||..|. ..|.|| .
QILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDRIS

IEKILLHPFF
.| .. ||.|
WEELFNHPWF
Kinase IrlC.AA ULK 1162-1246 22 1.5e-12 40.9 In-house 217-324 (324) Show / Hide 
Range on Protein: 1162-1246
Range on HMM: 217-324/324
Sequence Identity: 22% (25 aa)

EVLLEK--RKTKS---VDIFSMGCILFYLMTGGQHPFGDKFYRIV----NILTDK---PIL---EPLKHN---------LVACDLISQMISKNESDRPTI
..| ..  .|  .   .||.|.|||.... .|   .|.. |.  .    . .  .   .|.   .|....             |||..|. ..|.|| ..
QILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDRISW

EKILLHPFF
| |. ||.|
EEIFNHPWF
Kinase IrlC.AA TyrKc 981-1246 18 1.4e-11 -35.48 SMART 1-280 (280) Show / Hide 
Range on Protein: 981-1246
Range on HMM: 1-280/280
Sequence Identity: 18% (58 aa)

RKEENVLGRGSNGTLVFKGIWNNRIPVAIKQMQKMFNPLISKEIEVLITL--TNKNCYNIVRYIDQE-----EDESCVYLGLTLCDGSLQNLVEKGDNNL
 . . .||.|  |. |.||.|.  |.||.| ...     . .|....  |   ..|  ... .. |.     ..|    .    . |.|..   |  .. 
ITLGKKLGEGAFGE-VYKGTWK--IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK-

TLTQFLGYDINSSSKNNSRLLELIKDIVYGIQFLHQQGIVHNDLNPRNILIKDDR-FIISDLGLSKMEVTS--------SYSF----TMH--------AP
               ... ||.   .|  | ..||.....| ||  ||.|.....   ||| |||.              |.       .        ||
--------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAP

TGQEGFHPAEVLLEKRKTKSVDIFSMGCILFYLMTGGQHPFGD------KFYRIVNILTDKPILEPLKH----------NLVACDLISQMISKNESDRPT
         |.. ... |   |..| |  .. ..| || |  .      . ..... . .   ... ..            .   ...|    . .||||
---------ECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPT

IEKILLHPFF
 . |  | .|
FSEI--HECF
Kinase IrlC.AA RSK 1100-1188 27 1.3e-09 31.68 In-house 113-208 (278) Show / Hide 
Range on Protein: 1100-1188
Range on HMM: 113-208/278
Sequence Identity: 27% (27 aa)

IVYGIQFLHQQGIVHNDLNPRNILIKD----DRFIISDLGLSKMEVTSSYSFTMHAPTGQEGFHPAEVLLE--KRK--TKSVDIFSMGCILFYLMTG
||  ...||||||.| || | |||  |     .  ..| |..|     .... .. . .   . . |.| .  ...  .|..|..| |.... . ||
IVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF-RCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTG
Kinase IrlC.AA AGC 1100-1147 19 1.9e-09 19.06 In-house 162-265 (395) Show / Hide 
Range on Protein: 1100-1147
Range on HMM: 162-265/395
Sequence Identity: 19% (20 aa)

IVYGIQFLHQ-QGIVHND-LNPRNILIKDDRFI-ISDLGLSKMEVTS-----------------------------------------------------
|| ....||. .||.| | | | |||. .|  | ..| ||.|. ...                                                     
IVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDR

SYSF
 ..|
TWTF
Kinase IrlC.AA RSK 1221-1246 32 4.4e-07 22.32 In-house 248-278 (278) Show / Hide 
Range on Protein: 1221-1246
Range on HMM: 248-278/278
Sequence Identity: 32% (10 aa)

DLISQMISKNESDRPT-----IEKILLHPFF
|||..|  .....|..     .| |. ||.|
DLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase IrlC.AA Pkinase_Tyr 1091-1150 25 0.000956 13.31 Pfam 111-171 (270) Show / Hide 
Range on Protein: 1091-1150
Range on HMM: 111-171/270
Sequence Identity: 25% (16 aa)

SRLLELIKDIVYGIQFLHQQGIVHNDLNPRNILIKDDRFI-ISDLGLSKME-VTSSYSFTMH
..||.   .|  | ..|......| ||  ||.|....... |.| ||..    .. | ....
KDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKR
Pkinase_Tyr IrlC.AA Pkinase_Tyr 977-1012 36 0.002669 11.8 Pfam 1-36 (270) Show / Hide 
Range on Protein: 977-1012
Range on HMM: 1-36/270
Sequence Identity: 36% (15 aa)

FKFNRKEENVLGRGSNGTLVFKGIWN-----NRIPVAIKQM
 .|..|    ||.|. |. |.||.|.     ..||||.| .
ITFGKK----LGEGAFGE-VYKGTWKGDPDNTKIPVAVKML