IrlE

Species: Slime mold
Alias: DdisK096, DDB0229380, IrlE
External Links: DictyBase Link ,
Annotation:

Classification

Group: Other
Family: IRE

Sequence

Name Sequence Type Origin Length Description Download
IrlE.AA Protein None 1350 None Fasta, JSON
IrlE.kin_dom Protein Kinase Domain None 264 None Fasta, JSON

Protein domain

Protein domains of IrlE.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Ribonuc_2-5A IrlE.AA Ribonuc_2-5A 307-315 44 14.552408 0.81 Pfam 129-137 (137) Show / Hide
Range on Protein: 307-315
Range on HMM: 129-137/137
Sequence Identity: 44% (4 aa)

KIFKKYFLP
..|.||. |
EHFHKYYKP

Kinase IrlE.AA Ciliate-E3 667-680 35 0.009521 4.74 In-house 1-14 (202) Show / Hide
Range on Protein: 667-680
Range on HMM: 1-14/202
Sequence Identity: 35% (5 aa)

FDVQYLLTKGKFSL
..|| .| .|.|..
YTVQQILGCGQFGR

Kinase IrlE.AA IRE 906-1166 52 5.8e-164 551.0 In-house 1-292 (292) Show / Hide
Range on Protein: 906-1166
Range on HMM: 1-292/292
Sequence Identity: 52% (153 aa)

SNILGRGSNGTLVFKGIWNNRIPVAIKQMQKMFNPLISKEIEILIGLTNKNLN-LVGYIDQEEDENCVYLGLTLCDGSLQSLYDQSKLNEFINQNNNQNN
.||||||.|||||||||||.|||||.|||||.|||.||.||..||.|...| . .. |..||||...|||.|.||.||||....|.|.|.|||..||.||
NNILGRGCNGTLVFKGIWNGRIPVAVKQMQKEFNPFISREIQMLIKLESDNHPNVIRYYCQEEDDQFVYLALELCQGSLQDYVEQKKRNNFINSSNNSNN

NNNNN-----------RVLDLIIGMINGVIFLHDQNIVHNDLNPRNILVKD---------NRLIISDLGLSKMNVSSTYNFSTNAI--PTGQDGYHPVEV
||.||           |...||  ..||. .||.|||||.||.|.|||...         ||..|||.||.||.|...|.|..|..  |||..|.||.|.
NNKNNNNNNNQWQIHIRMWQLIKQCMNGLQHLHSQNIVHRDLKPHNILIHMNRPNQHGENNRFMISDFGLCKMLVEGRYSFTRNIRSGPTGTWGWHPPEM

LLE---KRKTKSVDVFSLGCLIYFIMTNGAHPFG-DKFSRLRYITKSKYNLSQLSNLNLVA----THLIELMISYDESKRPTLSSVLKHPLF
|.|   ||||||||.||.|| .|..||||.|||| ||..| ..|.|.||||.||...|...    ..||. ||..|..|||| ...|.||.|
LQEFCQKRKTKSVDIFSMGCVFYYVMTNGQHPFGNDKLHRQANILKGKYNLDQLKHHNHWHIVIACDLIHQMIHHDPQKRPTIKECLNHPFF

Kinase IrlE.AA Ciliate-E2-Unclassified 899-1166 17 1.3e-28 96.41 In-house 1-352 (352) Show / Hide
Range on Protein: 899-1166
Range on HMM: 1-352/352
Sequence Identity: 17% (63 aa)

FKFNKKESNILGRGSNGTLVFKGIWNNR--------IPVAIKQMQKMFNP-----LISKEIEIL--------------IGLTNKNLNLVGYIDQEEDENC
.|..|.    .|.|..|. |.| . ..         . ......||  .      .. ||....              | | ......| ......|...
YKIIKQ----IGQGGFGK-VYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQN

VYLGLTLCDGS--LQSLYDQSK----LNEFINQNNNQNNNNNNNRV----LDLIIGMINGVIFLHDQN-IVHNDLNPRNILVKDN----RLIISDLGLSK
.|. . .|.|   .| . ...|     |.  .......    .. .    ....   ..|  .|| .| |.| |. | |||...|    .. |.|.|.||
IYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISK

---MNVSSTYNF---------STNAIPT-GQDGYH----PVEVLLEKRKT----KSVDVFSLGCLIYFIMTNGAHPFG-------------------DKF
    |. .. ..         . ..  . |  .|     . ||| ..       ...|..|||...|.....  .||.                   .| 
KYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGY-YPFYDNNCEQHQQLITQWINNAYRKQ

SRLRYITKSKYNLSQLS-----NLNLVATHLIE----LMISYDESKRPTLSSVLKHPLF
 .   . |  .. ..       ...  | ..|.     |. .. .||.|.. .|.||.|
LYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase IrlE.AA Ciliate-E2 903-1166 17 1.9e-28 94.73 In-house 1-365 (365) Show / Hide
Range on Protein: 903-1166
Range on HMM: 1-365/365
Sequence Identity: 17% (66 aa)

KKESNILGRGSNGTLVFKGIWNNRI-----------------------PVAIKQMQKMFNPLISKEIEIL--------------IGLTNKNLNLVGYIDQ
 |  ...|.|. |.      |...                         .|.|.|.|     |..|| |.              |  .... |.. ... 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

EE--DENCVYLGLTLCDG-SLQSLYDQSKLNEFINQNNNQNNNNNNNRVLDLIIGMIN---------------GVIFLHDQN-IVHNDLNPRNILVKDNR
 .  |.|..|| . .|.| .|...  ..|.... ...  . .. . . .....   ..               .. .|| .| |.| |. | |||.    
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEK-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

LIISDLGLSK-------------MNVSSTYNFSTNAIPTG----------------QDGYHPVEVLL---------EKRKTKSVDVFSLGCLIYFIMTNG
. |.|.||||             ..   .. .. . . .|                  || . |.|          .|. ....|..|||...|. .. |
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF-G

AHPFGDKFSRLRYITKSKYNLS----------------QLSNLNLVATHLIEL----MISYDESKRPT-LSSVLKHPLF
 .||      .. | . |....                   .. . . .||      |. .|..||.|  . .|.|| |
KPPF------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase IrlE.AA S_TKc 903-1166 20 2.5e-22 81.41 SMART 1-231 (231) Show / Hide
Range on Protein: 903-1166
Range on HMM: 1-231/231
Sequence Identity: 20% (60 aa)

KKESNILGRGSNGTLVFKGIWNN-RIPVAIKQMQKMFNPLISKEIEILIGLTNKNLNLVGYIDQEEDENCVYLGLTLCDG---SLQSLYDQSK-------
 .  ...|.|. |. |.|.....    ||||..       | .||.||     .  |.| ..|  .| ...|. . .|||   .| .. .. .       
YEILRKIGKGAFGK-VYKCRHKKTGRIVAIKIIK----EHIRREIQILKK---HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LNEFINQNNNQNNNNNNNRVLDLIIGMINGVIFLHDQNIVHNDLNPRNILVKDNRLIISDLGLSKMNVSSTYNFSTNAIPTGQDGYHPV--------EVL
..|                .  ..  ..... ..|...|.| || | |||. . .. |.| ||..                    .. .        |||
FPE-H--------------ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL------------------TTFCGTPWYMAPEVL

LEKRKTK-SVDVFSLGCLIYFIMTNGAHPFGDKFSRLRYITKSKYNLSQLSNLNLVATHLIELMISYDESKRPTLSSVLK-------HPLF
     .| ..|. |.||..|  .. |  ||     ..  . .              | ..|. .  .| .||||   .|.       || |
---GYGKCKCDWWSCGCILYEMLC-GYPPFP-QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase IrlE.AA TKL 909-1164 15 9.4e-22 75.11 In-house 1-364 (364) Show / Hide
Range on Protein: 909-1164
Range on HMM: 1-364/364
Sequence Identity: 15% (59 aa)

LGRGSNGTLVFKGIWNN---------RIPVAIKQMQKMFNPL----------------------------ISKEIEILIGLTNKNLNLVGYID--QEEDE
.|.|. |  |.||.|..           .||.|.. .. . .                              .| ||.. .  .  |.| ..   .... 
IGSGGFG-EVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPC

NC-----------VYLGLTLC-DGSLQSLYDQSKLNEFINQNNNQNNNNNNNRVLDLIIGMINGVIFLHDQN--------IVHNDLNPRNILVK-DNR--
.|            ..   .|  ||| ...                     .. .......  |. .|| .|        |.| ||...||||. ...  
GCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNV

------------LIISDLGLSK-MNVSSTYNFS---------------TNAIPTGQDGYHPVEVLLEK----------------RKTKSVDVFSLGCLIY
            . |.|.|||. |. |.  | .               |.  . |  .. . ||| ..                  ....||.| | ...
SNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLW

FIMTNGAHPF--GDKFSRL---------RYITKSKYNLSQL------------SNLNLVATHLIELMISYDESKRPTLSSVLKHP
 |.|    |.   . ....          .. . .. .               ..       |..   ..| .|||. . .||. 
EILTRCR-PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase IrlE.AA Pkinase 901-1166 21 4.2e-19 68.64 Pfam 1-293 (293) Show / Hide
Range on Protein: 901-1166
Range on HMM: 1-293/293
Sequence Identity: 21% (67 aa)

FNKKESNILGRGSNGTLVFKGIWNNR-IPVAIKQMQKMFNPLISK--------EIEILIGLTNKNLNLVGYIDQEEDENCVYLGLTLCDGS--LQSLY--
. ...  ..|.|| |. |.|... .  . ||.|.. |  .   .|        ||.|.  |  .|   | ..|  ||.. .|. . .|.|   ...|.  
YHIGR--KIGSGSFGC-VYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNI--VRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDY

--DQSKLNEFINQNNNQNNNN--NNNRVLDLIIGMINGVIFLHDQNIVHNDLNPRNILVK-DNRL----IISDLGLSK-MNVSSTYNFSTNAIPTGQDGY
                ....     . . . .  .. |. ..|...|.| || | |||.. .. .     |.| ||.| ..   . | | .  ..|  .|
IST------------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWY

HPVEVLL-EKRKTKSVDVFSLGCLIYFIMTNGAHPFG--------DKFSRLRYITKSKYNLSQL-------------------SNLNLVATHLIELMISY
 . ||..  .  ...||..|.||..|  .. |  ||         |.  ... | . ..  .                      |..  . ..|. .. .
MAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCK

DESKRPTLSSVLKHPLF
| .||||   .|.|| |
DPKKRPTAEQILQHPWF

Kinase IrlE.AA PLK1 1015-1166 28 1.1e-14 44.47 In-house 105-253 (253) Show / Hide
Range on Protein: 1015-1166
Range on HMM: 105-253/253
Sequence Identity: 28% (44 aa)

IIGMINGVIFLHDQNIVHNDLNPRNILVKDN-RLIISDLGLSKMNVSSTYNFSTNAIPTGQDGYHPVEVLLEKRKTKSVDVFSLGCLIYFIMTNGAHPFG
.. ...|. .||...|.| ||   |. . |. .. | | ||      .     | .   |   |   ||| .|  .  ||..|.||..| ..  |  || 
MYQIVEGCQYLHNNKIIHRDLKLGNLFLNDHLQVKIGDFGLATKCEYDGERKKTLC---GTPNYIAPEVLNKKGHSFEVDIWSIGCIMYILLF-GQPPFE

DKFSRLRYITKSKYNLSQLSNLNLVATHLIELMISYDESKRPTLSSVLKHPLF
 |  .  |    | . .  |... .| .||. |.  | ..||| . ||.   |
TKCLKETYSRIKKNEYRIPSHISQPAAQLIRKMLDPDPTRRPTIEQVLNDEFF

Kinase IrlE.AA Ciliate-E3 1005-1056 41 1.4e-14 42.16 In-house 99-154 (202) Show / Hide
Range on Protein: 1005-1056
Range on HMM: 99-154/202
Sequence Identity: 41% (23 aa)

NNNNNRVLDLIIGMINGVIFLHDQNIVHNDLNPRNILVKDNR----LIISDLGLSK
|   | ..|..| .| |.| .| .|| | |..| ||||  |.    . |.|.|.||
NKTQNIIYDICIQIIQGMIAIHEKNIIHSDIKPDNILVDKNNNQLIIKICDFGESK

Kinase IrlE.AA Ciliate-E1 909-1060 27 2.9e-14 43.23 In-house 1-163 (202) Show / Hide
Range on Protein: 909-1060
Range on HMM: 1-163/202
Sequence Identity: 27% (46 aa)

LGRGSNGTLVFKG--IWNNRIPVAIKQMQKMFNPL------ISKEIEILIGLTNKNLNLVGYIDQEE-DENCVY-LGLTLCDGSLQSLYD--QSKLNEFI
.|.|| . .|||.  ..|| . ||.|  .  ||        ..||.  .    .|. ... .||. . |.|... . ...|. ||.   .  . .| | .
IGNGSFS-IVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHN-RL-EYW

NQNNNQNNNNNNNRVLDLIIGMINGVIFLHDQNIVHNDLNPRNILV-KDNRLIISDLGLSK--MNVS
.| ....|. .   .. .|. .| |.| ||..|| | |..| |||. ........|.|.||  .| .
QQCQQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQ

Kinase IrlE.AA ULK 903-1057 21 3.9e-12 38.75 In-house 1-191 (329) Show / Hide
Range on Protein: 903-1057
Range on HMM: 1-191/329
Sequence Identity: 21% (44 aa)

KKESNILGRGSNGTLVFKGIWNNR-----IPVAIKQMQ---KMFNP----------LISKEIEILIGLTNK------NLNLVGYIDQEEDE--NCVYLGL
   ...|| || |  |.||. ...     . ||.|...   .  ..          |. .||.|.  | ..      . | | ..|  |.   |..|. .
YCLNHCLGKGSFG-KVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIM

TLCDG-SLQSLYDQSKLNEFINQNNN------QNNNNNNNRVLDLIIGMINGVIFLHDQNIVHNDLNPRNILVKDN-------------RLIISDLGLSK
 .|.|  |.         ..|..|..       ... . . ..  ..  .||  .||..||.| |. | |||....             .| |.| |..|
EYCNGGDLE---------QYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAK

M
.
H

Kinase IrlE.AA CAMK 1081-1166 20 1e-11 33.29 In-house 290-425 (425) Show / Hide
Range on Protein: 1081-1166
Range on HMM: 290-425/425
Sequence Identity: 20% (28 aa)

EVLLEKR--------------KTKSVDVFSLGCLIYFIMTNGAHPFGDK---------------FSRLRYITKSKYNLS--QLSNLN-------------
|||. |.               ....|. |.|.. | ||  |  || ..                  .. |.| ||.    ..|..              
EVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILY-IMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISD

-------LVATHLIELMISYDESKRPTLSSVLKHPLF
         . .||  |  .| .||.|.. .|.|| .
EFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM

Kinase IrlE.AA TyrKc 903-1166 21 1.5e-11 -35.82 SMART 1-280 (280) Show / Hide
Range on Protein: 903-1166
Range on HMM: 1-280/280
Sequence Identity: 21% (64 aa)

KKESNILGRGSNGTLVFKGIWNNRIPVAIKQMQKMFNPLISKEIEILIGL--TNKN-LNLVGYIDQE-----EDENCVYLGLTLCDGSLQSLYDQSKLNE
 .   .||.|  |. |.||.|.  |.||.| ...     . .|..|.  |   ..| ..|.|.. |.     ..|    .    . |.|..    .. . 
ITLGKKLGEGAFGE-VYKGTWK--IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK-

FINQNNNQNNNNNNNRVLDLIIGMINGVIFLHDQNIVHNDLNPRNILVKDNR-LIISDLGLSKMNVSS--------TYNF----STNA-IPTGQDGYHPV
            ..   |.  .   .|  .||..|..| ||  ||.||..|.   ||| |||.   .         .|      .... .|       . 
-----------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPI---RWMAP

EVLLEKRKTKSVDVFSLGCLIYFIMTNGAHPFGD------KFSRLRYITKSKYNLSQLSN---------LNLVATHLIELMISYDESKRPTLSSVLKHPL
|.. ... |   ||.| | ... |.|.|. |  .      . ....   |. | . |  |            . . ...    .| ..||| | .  | .
ECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEI--HEC

F
|
F

Kinase IrlE.AA ULK 903-1057 24 3.4e-10 32.43 In-house 1-187 (324) Show / Hide
Range on Protein: 903-1057
Range on HMM: 1-187/324
Sequence Identity: 24% (47 aa)

KKESNILGRGSNGTLVFKG--IWNN--RIPVAIKQMQ---KMFNP----------LISKEIEILIGLTN-KNLN--LVGYIDQEEDE--NCVYLGLTLCD
   ...|| || |  |.||  . .|     ||.|...      ..          |. .||.|.  | . |. |   | ..|  |.   | .|. . .|.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

G-SLQSLYDQS-KLNEFINQNNNQNNNNNNNRVLDLIIGMINGVIFLHDQNIVHNDLNPRNILVKDN-------------RLIISDLGLSKM
|  |...  .  ||.|        ... . . ..  ..  .||  .||..||.| |. | |||....             .| |.| |..|.
GGDLEQYIKKNKKLPE-T-E---EKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKH

Kinase IrlE.AA CAMK 908-1057 16 2.4e-09 25.51 In-house 1-245 (425) Show / Hide
Range on Protein: 908-1057
Range on HMM: 1-245/425
Sequence Identity: 16% (44 aa)

ILGRGSNGTLVFKGIWN-NR------------IPVAIKQMQK--MFN-----------------------------PLISKEIEILIGLTN-----KNLN
.||||| |. |...|   .               |||| . |  . .                               . .||||.  | .     .  |
TLGRGSFGK-VKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPN

LVGYIDQEED-------------------ENCVYLGL---TLCDGS--LQSLYDQSKLN------------------------EFINQNNNQNNNNNNNR
..  ..  ||                   ....|. .    .|.|   .. |.|  . .                         .. |            
IIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQ------------

VLDLIIGMINGVIFLHDQNIVHNDLNPRNILVKDN------------------RLIISDLGLSKM
       .. .| ..|..|||| || | |||. ||                   . |.| |....
-------ICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANK

Kinase IrlE.AA ULK 1081-1166 20 9.8e-07 19.99 In-house 217-324 (324) Show / Hide
Range on Protein: 1081-1166
Range on HMM: 217-324/324
Sequence Identity: 20% (22 aa)

EVLLEK--RKTKS---VDVFSLGCLIYFIMTNGAHPFGDKFSRLR---------------YITKSKYNLS---QLSNLNLVATHLIELMISYDESKRPTL
..| ..  .|  .   .|..||||..| . ..   .|.. |. .                || . . .     .  ..      ||  |. |||..| . 
QILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDRISW

SSVLKHPLF
  ...||.|
EEIFNHPWF

Kinase IrlE.AA ULK 1081-1166 20 3e-06 18.01 In-house 221-329 (329) Show / Hide
Range on Protein: 1081-1166
Range on HMM: 221-329/329
Sequence Identity: 20% (22 aa)

EVLLEK--RKTKS---VDVFSLGCLIYFIMTNGAHPFGDKFSRLR-YITKSKYNL---------SQLSN---------LNLVATHLIELMISYDESKRPT
..| ..  .|  .   .|..||||..| . ..   ...  |. .  .| .. .|.         .|  .         .      ||  |. |||..| .
QILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDRIS

LSSVLKHPLF
   ...||.|
WEELFNHPWF

Kinase IrlE.AA Pkinase_Tyr 1024-1056 41 0.000996 13.25 Pfam 126-159 (270) Show / Hide
Range on Protein: 1024-1056
Range on HMM: 126-159/270
Sequence Identity: 41% (14 aa)

FLHDQNIVHNDLNPRNILVK-DNRLIISDLGLSK
.|...|..| ||  ||.||. .|   |.| ||..
YLESKNCIHRDLAARNCLVTENNVVKICDFGLAR

Kinase IrlE.AA Pkinase_Tyr 899-957 29 0.002147 12.12 Pfam 1-66 (270) Show / Hide
Range on Protein: 899-957
Range on HMM: 1-66/270
Sequence Identity: 29% (21 aa)

FKFNKKESNILGRGSNGTLVFKGIWN-----NRIPVAIKQMQKMFNPLIS-------KEIEILIGL-TNKNL
 .|.||    ||.|. |. |.||.|.     ..||||.| . |              .|..|.  |  ..|.
ITFGKK----LGEGAFGE-VYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNI

Ribonuc_2-5A IrlE.AA Ribonuc_2-5A 1243-1296 29 0.000348 17.64 Pfam 41-94 (137) Show / Hide
Range on Protein: 1243-1296
Range on HMM: 41-94/137
Sequence Identity: 29% (16 aa)

WNQSLDYQLVDSLSNQIEKKVASYKFDQLHDLIRFIRNTLQHYNQI-YRDLKQIL
|.  .|  ..|..  .  |.   |..|.. ||.|..||   ||.    ...|.||
WHKKIDKAFMDDMGKYYRKR-KNYYGDSVRDLLRAMRNKKHHYHEMKPEEMKEIL

Ribonuc_2-5A IrlE.AA Ribonuc_2-5A 1312-1345 21 4.242976 2.76 Pfam 102-137 (137) Show / Hide
Range on Protein: 1312-1345
Range on HMM: 102-137/137
Sequence Identity: 21% (8 aa)

LNYFESKFPTLIIFLFNHFSAIPEIKNSIHFS---ND
|.|| ..|| | .. .. ..  .. ..  ||.   ..
LQYFTERFPHLLMHCYHVMQE-CHCEHEEHFHKYYKP