Gene 22828 (Tetrahymena)

22828

Species: Tetrahymena
Alias: PreTt22828, 169.m00068, 871, TTHERM_00937690, 22828
External Links: Tetrahymena Genome Database (TGD)
Annotation: Secondary Group: Other, Secondary Family: Ciliate_C8_Cterm,

Classification

Group: Other
Family: Ciliate-C8
Subfamily: C2

Sequence

Name Sequence Type Origin Length Description Download
22828.AA Protein None 658 None Fasta, JSON
22828.kin_dom Protein Kinase Domain None 199 None Fasta, JSON
22828.kin_dom2 Protein Kinase Domain None 202 None Fasta, JSON
22828.NA RNA None 1977 None Fasta, JSON

Protein domain

Protein domains of 22828.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 22828.AA C2 6-110 37 1.9e-44 149.79 In-house 106-245 (245) Show / Hide 
Range on Protein: 6-110
Range on HMM: 106-245/245
Sequence Identity: 37% (53 aa)

QKYKKYCREKNQYPDKKMKEILTIQILDGISFLHQKSFLHRDIKPNNILLQFDNQNNPIIKICD----------LGFASFISPSQSKIHT----------
. | . ||..|.||.. ||.|..||..|.|..||.....||||||.|.|.|||.|..|.||.||          . |||......|.||.          
KQYFNRCRKQNSYPCQQMKMIMAIQMMDSINYLHRFDIVHRDIKPSNFLYQFDQQGIPTIKLCDYHIQYQKKCDFDFASKLKYNKSRIHFSKFKWTQQYY

--------------KQSDLFQ-VGIVLLELDNIQKFDFLK
              |.||||. ||.|||||||.| ... .
QHIFAPEVYQNIYKKNSDLFSTVGYVLLELDNMQQYTICC
Kinase 22828.AA Ciliate-C8 6-97 32 6.6e-34 118.93 In-house 103-238 (238) Show / Hide 
Range on Protein: 6-97
Range on HMM: 103-238/238
Sequence Identity: 32% (44 aa)

QKYKKYCREKNQYPDKKMKEILTIQILDGISFLHQKSFLHRDIKPNNILLQFDNQNNPIIKICD------LGFASFISPSQS---------KIHT-----
..| ..||.|..||...||||..||..|....||.. ..||||||.|.|..||.|..|.||.||      .||||... ..|         .. .     
KQYFDRCRKKQSYPSQQMKEIIAIQMIDSVNYLHCFNIMHRDIKPHNFLVCFDQQYQPTIKLCDFKKQCDFGFASQLPKNKSHYHSKKFKGTDQYIEMYF

-----------------KQSDLFQ-------VGIVL
                 .|||.|.       ||.||
CGNWGYFAPEVEKKQSRIQSDIFSKKSDSYSVGLVL
Kinase 22828.AA C8 6-85 42 5.8e-29 97.7 In-house 107-186 (226) Show / Hide 
Range on Protein: 6-85
Range on HMM: 107-186/226
Sequence Identity: 42% (34 aa)

QKYKKYCREKNQYPDKKMKEILTIQILDGISFLHQKSFLHRDIKPNNILLQFDNQNNPIIKICDLGFASFISPSQSKIHT
... ...|.|.|...|.||||..||..||....|.| ..||||||.|.|...|......||.||.||||..| ..|.|..
KQLYDERRNKQQQFSKEMKEIIAIQMIDGVNYIHCKNIMHRDIKPHNFLVCLDQNYGFEIKLCDFGFASQVSKNKSHIQS
Kinase 22828.AA Ciliate-E2 9-100 17 6.6e-19 61.51 In-house 122-289 (365) Show / Hide 
Range on Protein: 9-100
Range on HMM: 122-289/365
Sequence Identity: 17% (31 aa)

KKYCREKNQYPDKK--------MKEILTI--QILD---------------GISFLHQKS-FLHRDIKPNNILLQFDNQNNPIIKICDLGFAS--------
..|......  ...        .|||..|  |||.               .. .||.|   .||||||.|||.         |||.|.|..         
FDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF---------IKIIDFGLSKKYDDDNQN

----------------------------------------FISP----SQS-------KIHTKQSDLFQVGIVLLEL
                                        . .|    ...       | .....|.. .|..| |.
RTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEM
Kinase 22828.AA CMGC 28-85 22 1.7e-16 49.83 In-house 186-283 (513) Show / Hide 
Range on Protein: 28-85
Range on HMM: 186-283/513
Sequence Identity: 22% (22 aa)

TIQILDGIS--FLHQKS--FLHRDIKPNNILLQFDNQN----------------NPIIKICDLGFASFISPSQ--------------------SKIHT
. ||| |.   ..|..   ..|||.|| |||.  ....                | ..|||| |.| ...| .                    .. .|
MYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYT
Kinase 22828.AA CAMK 30-85 25 3.3e-16 48.05 In-house 187-278 (425) Show / Hide 
Range on Protein: 30-85
Range on HMM: 187-278/425
Sequence Identity: 25% (23 aa)

QILDGISFLHQKSFLHRDIKPNNILLQFDNQNNP-------------IIKICDLGFASFISPSQS-----------------------KIHT
||.... ..|..   |||.|| ||||. .| ...              |||.| ||| .. |...                       | .|
QICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKT
Kinase 22828.AA Pkinase 30-85 36 7.4e-15 53.62 Pfam 116-170 (293) Show / Hide 
Range on Protein: 30-85
Range on HMM: 116-170/293
Sequence Identity: 36% (21 aa)

QILDGISFLHQKSFLHRDIKPNNILLQFDNQNNPIIKICDLGFASFI-SPSQSKIHT
||| |. ..|.....|||.|| |||.  ........|||| |.| ..   ..|  .|
QILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTT
Kinase 22828.AA CDK 27-73 36 1e-14 43.32 In-house 113-160 (284) Show / Hide 
Range on Protein: 27-73
Range on HMM: 113-160/284
Sequence Identity: 36% (18 aa)

LTIQILDGISFLHQKSFLHRDIKPNNILLQFDNQNNPI---IKICDLGFA
.. |.|.|....|.. ..|||.||.|||.  .|. ..    .|| | |.|
YMWQLLRGLHYCHSNWIMHRDLKPQNILI--NNNGEVKCGRLKIADFGLA
Kinase 22828.AA STE 28-83 38 2e-14 47.49 In-house 157-204 (359) Show / Hide 
Range on Protein: 28-83
Range on HMM: 157-204/359
Sequence Identity: 38% (22 aa)

TIQILDG-ISFLHQKSFLHRDIKPNNILLQFDNQNNPIIKICDLGFASFISPSQSKI
. ||| |  ..||..   |||||| ||||         .|.|| |... ...| ..|
CRQILKGLLYYLHSHHIIHRDIKPANILL---------VKLCDFGVCGQLTDSMANI
Kinase 22828.AA CDC2 9-73 37 2.1e-11 30.77 In-house 87-150 (301) Show / Hide 
Range on Protein: 9-73
Range on HMM: 87-150/301
Sequence Identity: 37% (26 aa)

KKYCR----EKNQYPDKKMKEILTIQILDGISFLHQKSFLHRDIKPNNILLQFDNQNNPIIKICDLGFA
||| .     . . |  . |... .|||.|..|.||.  .|||.|| |||.  . .    ||| | | |
KKYMDMSIPKNKHMPPQLVKSYM-YQILQGVHFCHQRRIMHRDLKPQNILIDKKGN----IKIADFGLA
Kinase 22828.AA Ciliate-E1 4-86 25 5.2e-09 25.92 In-house 82-174 (202) Show / Hide 
Range on Protein: 4-86
Range on HMM: 82-174/202
Sequence Identity: 25% (24 aa)

SKQKYKK---------YCREKNQYPDKKMKEILTIQILDGISFLHQKSFLHRDIKPNNILL-QFDNQNNPIIKICDLGFASFISPSQSKIHTK
| ..| .          |...... . . |. ...|..||.. |||. ..|||||| |||  ...| ..  . |....  . .. .| | .|.
SLKDYLQNHNRLEYWQQCQQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTH
Kinase 22828.AA C8 86-97 75 0.00023 11.19 In-house 215-226 (226) Show / Hide 
Range on Protein: 86-97
Range on HMM: 215-226/226
Sequence Identity: 75% (9 aa)

KQSDLFQVGIVL
.|||||.||.||
IQSDLFSVGLVL
Kinase 22828.AA C2 286-480 34 7.1e-89 301.57 In-house 1-245 (245) Show / Hide 
Range on Protein: 286-480
Range on HMM: 1-245/245
Sequence Identity: 34% (85 aa)

GGKGVIIGAYNLKDKRDCVLKIQKVQS-----KSRIIKEISILKCCQ-MPLIVKLYNSFYLDVAKKED------------------------FVVYELEK
|..| ...|.| |..|...||||..||     .....||..|...|| ||.|.|.||.|||.| ||||                        |||||.|.
GAFGLVLKAFNKKQNRHVALKIQECQSNDINGMHEVQKEYGIMRQCQNMPYIIKVYNYFYLTVNKKEDEDEDNDEEEKEQENIKKQKNEKKIFVVYEQEF

CDCDLKAYLEKKQNGQ-QLSQEVKEEIAIQMMDSVNYMHKHNIIHRDIKPQNFLVQESNSSIPAIKLSD----------FDEADYLRLDQDLDYDHFFNT
|...||.|...... . ...|..|...|||||||.||.|...|.||||||.|||.|.....||.|||.|          ||.|. |....   ..  |. 
CQGNLKQYFNRCRKQNSYPCQQMKMIMAIQMMDSINYLHRFDIVHRDIKPSNFLYQFDQQGIPTIKLCDYHIQYQKKCDFDFASKLKYNKSRIHFSKFKW

GDWTVKEYFAP---------NCDGCGTFGYWAPEQIYQKDNNIGA
   ...  |||         |.| ..|.||...|.....  .|  
TQQYYQHIFAPEVYQNIYKKNSDLFSTVGYVLLELDNMQQYTICC
Kinase 22828.AA Ciliate-C8 286-477 36 2.6e-81 276.42 In-house 1-221 (238) Show / Hide 
Range on Protein: 286-477
Range on HMM: 1-221/238
Sequence Identity: 36% (82 aa)

GGKGVIIG-------AYNLKDKRDCVLKIQKVQSKSRIIKEISILKCCQMPLIVKLYNSFYLD-VAKKED-----------------FVVYELEKCD--C
|..|....       ... ...|.||.||||.|....|.....| ..||||..|..|..|||. . ||||                 |.|.|.|||.  |
GAFGMVLKAQNKKQNRKVALKFRECVNKIQKNQMEHEIKEYEMIMQFCQMPFVVQVYDCFYLMEENKKEDDDGNDKIVQTQEKIKKSFFVMEMEKCQQNC

DLKAYLEKKQNGQ-QLSQEVKEEIAIQMMDSVNYMHKHNIIHRDIKPQNFLVQESNSSIPAIKLSD------FDEADYLRLDQDLDYDHFFNTGDWTVKE
.|| |... .. | ..||. ||.|||||.|||||.| .||.||||||.||||.......| |||.|      |. |..|. ...  ... |.. |.....
NLKQYFDRCRKKQSYPSQQMKEIIAIQMIDSVNYLHCFNIMHRDIKPHNFLVCFDQQYQPTIKLCDFKKQCDFGFASQLPKNKSHYHSKKFKGTDQYIEM

YFAPNCDGCGTFGYWAPEQIYQ-KDNN
||      ||..||.|||.... ....
YF------CGNWGYFAPEVEKKQSRIQ
Kinase 22828.AA C8 277-477 33 4e-71 242.6 In-house 1-209 (226) Show / Hide 
Range on Protein: 277-477
Range on HMM: 1-209/226
Sequence Identity: 33% (76 aa)

SKSFNLINQGGKGVIIGAYNLKDKRDCVLKIQKVQSKSRIIKEISILKCCQMPLIVKLYNSFYLD-VAKKEDFVVYELEKCD-----------CDLKA--
...|.....|..|... |.|.||.|..|||.||.|.|..| ...|| |...||.....|...... ....|...|.|.|||.           |...   
FNNFQYLSFGAYGMVLKAKNVKDNREIVLKFQKCQNKQDIQNIESIMKEYEMPQVFQQYDFYVNEYDCFYEMYEVFEEEKCSNEKIVQTEEKSCFVMEME

---------YLEKKQNGQQLSQEVKEEIAIQMMDSVNYMHKHNIIHRDIKPQNFLVQESNSSIPAIKLSDFDEADYLRLDQDLDYDHFFNTGDWTVKEYF
         |.|.... ||.|.| ||.|||||.|.|||.| .||.||||||.||||.........|||.||..|.... ... ......||         
LCEQNLKQLYDERRNKQQQFSKEMKEIIAIQMIDGVNYIHCKNIMHRDIKPHNFLVCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNT---------

APNCDGCGTFGYWAPEQIYQKDNN
      |||..|.|||.....||.
------CGTWAYFAPEIEKKQDNQ
Kinase 22828.AA CDC2 278-424 25 1.9e-22 65.35 In-house 2-147 (301) Show / Hide 
Range on Protein: 278-424
Range on HMM: 2-147/301
Sequence Identity: 25% (40 aa)

KSFNLINQGGKGVIIGAYNLKDKRDCVLKIQKVQSKSRI-------IKEISILKCCQ-MPLIVKLYNSFYLDVAKKEDFVVYELEKCDCDLKAYLE-KKQ
.. . |. |  ||.. . ...... ..||  .. . . .       |.|||.||  .  | ||||   ..     .  . | |   .|.||| |.. ...
QKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ----NKLYMVFEY--LDMDLKKYMDMSIP

NGQQLSQEVKEEIAIQMMDSVNYMHKHNIIHRDIKPQNFLVQESNSSIPAIKLSDF
 ........  ....|. . |.. | . |.|||.|||| |. .. .    ||..||
KNKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGN----IKIADF
Kinase 22828.AA CMGC 277-424 18 2.1e-20 62.89 In-house 1-248 (513) Show / Hide 
Range on Protein: 277-424
Range on HMM: 1-248/513
Sequence Identity: 18% (45 aa)

SKSFNLINQGGKGVIIGAYN--------------LKDKRDCVLKIQK-VQSKS--------------RIIKEISILKCCQ-----------------MPL
 .  . | .|  ||   ...               .... . .|. | .. .               |.. ||.|||. .                  . 
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IVKLYNSFY-LDVAKKED-----------FVVYELEKCDCDLKAYLEKKQ------NGQQLSQEV------------KEEIA------IQMMDSVN--YM
|||||..||  . ...|.            .    | .|.||. |....|      ... ||. .            .  .        |.  ...  |.
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HKHN--IIHRDIKPQNFLVQESNSSI----------------PAIKLSDF
|.|.  |||||.||.| |. . . .|                  .|. ||
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDF
Kinase 22828.AA Ciliate-E1 283-424 23 2.6e-20 63.08 In-house 1-158 (202) Show / Hide 
Range on Protein: 283-424
Range on HMM: 1-158/202
Sequence Identity: 23% (37 aa)

INQGGKGVIIGAYNLKDK----RDCVLKIQKVQSKSRIIKEISILKCCQMPLIVKLYNSFYLDVAKKED--FVVYELEKCDCDLKAYLE----------K
| .|. .... |.. ...     . . ...  ...  . .||   .. .. .. . |   ..|. |...  . .  .|.|.| || ||.          .
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQC

KQNGQQLSQEVKEEIAIQMMDSVNYMHKHNIIHRDIKPQNFLVQESNSSIPA-IKLSDF
.|| .|.... |..|..|. | ....| .||||||||||| |.  ..  . . . .|.|
QQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKF
Kinase 22828.AA CAMK 303-424 21 1.3e-16 49.36 In-house 55-240 (425) Show / Hide 
Range on Protein: 303-424
Range on HMM: 55-240/425
Sequence Identity: 21% (41 aa)

CVLKIQKV-----------QSKSRIIKEISILKCCQ-------MPLIVKLYNSFYL----------DVAKK-----EDFVVYEL---EKCDC-----DLK
|  ||.|            ... .. .||.|.| .|        | |.|||  .            .  .|     .....  .   | |.      || 
CY-KIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLF

AYLEKKQN-------GQQLSQE--VKEEIAI----QMMDSVNYMHKHNIIHRDIKPQNFLVQESNSSIP------------A-IKLSDF
 |. .. .       .  . ..  ..|. |     |. . |.|.|.|||.|||.|| | |....|.. .            . ||..||
DYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDF
Kinase 22828.AA CDK 356-424 29 3.2e-15 45.01 In-house 100-157 (284) Show / Hide 
Range on Protein: 356-424
Range on HMM: 100-157/284
Sequence Identity: 29% (21 aa)

CDCDLKAYLEKKQNGQQLSQEVKEEIAIQMMDSVNYMHKHNIIHRDIKPQNFLVQESNSSIPA--IKLSDF
.| ||| |..           .|  .  |... ..|.|...|.|||.|||| |. .  .      .|. ||
MDHDLKKYMD-----------IK-CYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVK-CGRLKIADF
Kinase 22828.AA Pkinase 304-424 27 1.4e-13 49.12 Pfam 31-156 (293) Show / Hide 
Range on Protein: 304-424
Range on HMM: 31-156/293
Sequence Identity: 27% (36 aa)

VLKIQKVQSKSRIIK----EISILKCCQMPLIVKLYNSFYLDVAKKEDFVVYELEKCDC-----DLKAYLEKKQNGQQL--SQEVKEEIAIQMMDSVNYM
..| ..  |. ....    ||.|.| .. | ||.|| .|.      .| .   .| |..     ||..|..  ...  .  | ..   .. |.   ..|.
IIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-----KDHIYMVMEYCEGGLYVMDLFDYIST-WRHGCFYFSEWECKFYMYQILRGLEYC

HKHNIIHRDIKPQNFLVQESNSSI-PAIKLSDF
|...|||||.||.|.|.  .|  | . .|..||
HSMGIIHRDLKPENILID-NNGHIDACVKICDF
Kinase 22828.AA S_TKc 280-548 20 2.4e-13 18.78 SMART 1-231 (231) Show / Hide 
Range on Protein: 280-548
Range on HMM: 1-231/231
Sequence Identity: 20% (63 aa)

FNLINQGGKG---VIIGAYNLKDKRDCVLKIQKVQSKSRIIKEISILKCCQMPLIVKLYNSFYLDVAKKEDFVVYELEKCDC---DLKAYLEKKQNG---
. .... |||   .   ... |..| . .|| |     .|..||.|||  . | ||||| .|.       |..   .| ||    ||. |..|.. .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK-HHPNIVKLYDVFQD------DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

QQLSQEVKEEIAIQMMDSVNYMHKHNIIHRDIKPQNFLVQESNSSIPAIKLSDFDEADYLRLDQDLDYDHFFNTGDWTVKEYFAPNCDGCGTFGYWAPEQ
....  .   .. |. . ..|.|.|.|||||.||.| |. |       ||..||  |  |                             |||  | ||| 
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL--------------------------TTFCGTPWYMAPEV

IYQKDNNIGAEGAKH-----------IAMSLEKCQNITSLNLNLEGNQIGAEGAKHIAMSLEKCQNITSLNLNLWDNN----IGAEGAK--------HIA
.          |  .           ..  |   .   . ....  ..||              .   ..  .... .    ..|  |         |  
L----------GYGKCKCDWWSCGCILYEMLC-GYPPFP-QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPW

M
.
F
Kinase 22828.AA Ciliate-E2 280-424 20 2.2e-12 38.83 In-house 1-200 (365) Show / Hide 
Range on Protein: 280-424
Range on HMM: 1-200/365
Sequence Identity: 20% (44 aa)

FNLINQGGKG---VIIGAYNLKDKRD-----------------------CVLKIQKVQSKSRIIKEISILKCCQ----------------MPLIVKLYNS
...|.. |.|   ..  . . |....                         .||.| . .  | .||.|... .                 | |.|.| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FYLDVAKKEDFVVYELEKCDC-DLKAYLE---KKQNGQ-----QLSQEVKEEIAIQMMD---------------SVNYMHKHN-IIHRDIKPQNFLVQES
|.    |... . . .| |.  ||. |..   ||.| .     ... .   .|  |  .                ..|.|. | ||||||||.| |.   
FQE---KDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF---

NSSIPAIKLSDF
      ||..||
------IKIIDF
Kinase 22828.AA STE 390-424 48 1.7e-10 33.42 In-house 166-191 (359) Show / Hide 
Range on Protein: 390-424
Range on HMM: 166-191/359
Sequence Identity: 48% (17 aa)

NYMHKHNIIHRDIKPQNFLVQESNSSIPAIKLSDF
.| |.|.||||||||.| |.         .||.||
YYLHSHHIIHRDIKPANILL---------VKLCDF
Kinase 22828.AA TyrKc 280-503 15 0.000276 -153.34 SMART 1-280 (280) Show / Hide 
Range on Protein: 280-503
Range on HMM: 1-280/280
Sequence Identity: 15% (45 aa)

FNLINQGGKG----VIIGAYNLKDKRDCVLKIQKVQSKSRIIKEISILKCC--QMPLIVKLYNSFYLD----VAKKEDFVVYELEKCDCDLKAYLEKKQN
  |. . | |    |  | ..    ...  |  |  ..  ...|..|..    . | ||.||     .    .  .  ..| |. .   ||| || |...
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPH-GDLKDYLRKHRP

GQQLSQEVKEEIAIQMMDSVNYMHKHNIIHRDIKPQNFLVQESNSSIPAIKLSDFDEADYLRLD------QDLDYDHFFNTGD--WTVK----EYFAPNC
   |. . . ....|  .  .| |..|.||||.   | || | .     .| |||  . ..  |      .|         |.  . ..    | .    
K--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI---N

DG---------------------CGTFGY------WAPEQIYQKDNNI-----GAE--------GAKHIAMSLEKCQNI--------TSLNLNL
.|                     ...  .        .......  .       ..          . . .  ..| .         . .   .
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 22828.AA STE 280-339 20 0.000425 10.51 In-house 1-100 (359) Show / Hide 
Range on Protein: 280-339
Range on HMM: 1-100/359
Sequence Identity: 20% (20 aa)

FNLINQGGK---GVIIGAYNLK---------------DKRDCVLKIQKVQS--------------------KSRIIKEISILKCCQ--MPLIVKLYNSFY
. .| . ||   |.   |.| |                .. .  |. ....                    . .|.|||.|.|.|.   | ||| | ...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF