Gene 15633 (Tetrahymena)

15633

Species: Tetrahymena
Alias: 587, TTHERM_00295230, 15633, 3692.m00096, PreTt15633, 27.m00293
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: AGC
Family: AktR

Sequence

Name Sequence Type Origin Length Description Download
15633.AA Protein None 880 None Fasta, JSON
15633.kin_dom Protein Kinase Domain None 259 None Fasta, JSON
15633.NA RNA None 2643 None Fasta, JSON

Protein domain

Protein domains of 15633.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 15633.AA AGC 161-419 31 9.60000000001e-167 435.19 In-house 1-395 (395) Show / Hide 
Range on Protein: 161-419
Range on HMM: 1-395/395
Sequence Identity: 31% (124 aa)

FDVLKKIGLGGFSEVYLARRK------DNGQFVALKVIKKKT---LIKKRRKLYVYNE------------KNTMIALKD---------NPFIVQ-FFFAF
|..|| || |.|..|||.|.|      |.|.. |.||.|||.   ..||.   ....|            .| .  ..          .||||.  ...|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTREK--LIFVLEYCP---------GG-ELFYHLN---QERRFKEEQAGILFAQ-------ILEGIEFLHS-KNIIYRD-LKPENILLDMNGYVKLADFG
|. ..  | ||.||.|         || |||.||    .|.|| ||.| . .|.       |. ..|.||| ..||.|| ||||||||| .|..||.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSKVLKSKD--------------------------------------------------QLNYTFCG--SHEYMAPEMIQKKGHTFAVDYYS--LGVLLY
|.|......                                                  ....||||  ..||||||..    ...|.|..|  ||.|.|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

ELVAGIPPFSSDN----------KTDLLEKAL------TKEVKFPP---------KQFSSQLQDFIKQLMIKDPTKRLGAKS------GISEIRKHPWC
|...|.|||..||          . .. .| .      ...||||.         ..||....|.||.|. |||.||||..       |..||..||| 
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 15633.AA AktR 161-419 49 6.5e-164 550.84 In-house 1-268 (268) Show / Hide 
Range on Protein: 161-419
Range on HMM: 1-268/268
Sequence Identity: 49% (133 aa)

FDVLKKIGLGGFSEVYLARRK-DNGQFVALKVIKKKTLIKKRRKLYVYNEKNTMIALKDNPFIVQFFFAFQTREKLIFVLEYCPGGELFYHLNQERRFKE
|.|.| .| |.|..|||...| ||....|.|.||||..|..... ....|.| |......||||.....|||.|||.|..|||||||||.||.....|.|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

EQAGILFAQILEGIEFLHSK-NIIYRDLKPENILLDMNGYVKLADFGLSK--VLKSKDQLNYTFCGSHEYMAPEMIQK-KGHTFAVDYYSLGVLLYELVA
||| . ||||| ..|.||.. |||||||||||||||..|.||..||||||  . ...|...|.|||..||||||||.| |||...||....|...||.|.
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GIPPFSSDNKTDLLEKALTKE-VKFPP-KQFSSQLQDFIK-QLMIKDPTKRLG-AKSGISEIRKHPWC
|.||| ..|......| ..|. .|||. ..||||..|.|. .|. |.|.|||| ...|..||..|||.
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 15633.AA Akt 161-419 45 6.2e-119 381.85 In-house 1-264 (264) Show / Hide 
Range on Protein: 161-419
Range on HMM: 1-264/264
Sequence Identity: 45% (120 aa)

FDVLKKIGLGGFSEVYLARRKDNGQFV-ALKVIKKKTLIKKRRKLYVYNEKNTMIALKDNPFIVQFFFAFQTREKLIFVLEYCPGGELFYHLNQERRFKE
||.|| .| | |  |.|.. ||....  |.||.||. .|.|. . ..  |.|     . .||||.  ..||| .|| ||..||.|||||||| ..|||.|
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCN-HPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSE

EQAGILFAQILEGIEFLHSKNIIYRD-LKPENILLDMNGYVKLADFGLSKVL-KSKDQLNYTFCGSHEYMAPEMIQKKGHTFAVDYYS-LGVLLYELVAG
..|    |.|  .||.|||||||||| |||||||.| .|...|.||||.|   .. ..  .||||. ||.|||.....||| ||| .. ||...||.  |
DRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCG

IPPFSSDNKTDLLEKALTKEVKFPPK-QFSSQLQDFIKQLMIKDPTKRLG-AKSGISEIRKHPWC
 ||| ....  . .| ....||||.| ..| . .|.|..|  |||.|||| ..... ||. ||| 
RPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 15633.AA SGK 161-419 41 5e-116 359.92 In-house 1-283 (283) Show / Hide 
Range on Protein: 161-419
Range on HMM: 1-283/283
Sequence Identity: 41% (119 aa)

FDVLKKIGLGGFSEVYLARRKDN------------------GQFVALKVIKKKTLI-------KKRRKLYVYNEKNTMIALKDNPFIVQFFFAFQTREKL
|| ||.|| |.| .||....||                   ..| |.||..|.. |       ||    ..  |.|. . .   ||||.  .|||| .||
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

IFVLEYCPGGELFYHLNQERRFKEEQAGILFAQILEGIEFLHSKNIIYRDLKPENILLDMNGYVKLADFGLSK-VLKSKDQLNYTFCGSHEYMAPEMIQK
 ||..|  |||.||||. |..|.| .| .  |.|   .| |||..||||||||||||||  |...| ||||.|   | .|    ||||. ||.|||...|
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDT-TFTFCGTPEYLAPEVLRK

KGHTFAVDYYSLGVLLYELVAGIPPFSSDNKTDLLEKALTKEVKFPPKQFSSQLQDFIKQLMIKDPTKRLGAKSGISEIRKHPWC
..|  .|| ..|| .|||.  |.||| | ||  . .. . .. ..|| |.|..  | |..|  |||.||||.| .  ||..||. 
QPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPP-QMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase 15633.AA S_TKc 161-419 34 1.1e-101 344.98 SMART 1-231 (231) Show / Hide 
Range on Protein: 161-419
Range on HMM: 1-231/231
Sequence Identity: 34% (94 aa)

FDVLKKIGLGGFSEVYLARRKDNGQFVALKVIKKKTLIKKRRKLYVYNEKNTMIALKDNPFIVQFFFAFQTREKLIFVLEYCPG--GELFYHLNQERR--
...|.||| |.|..||..| |. |. ||.|.||            ...| . .    . |.||... .||. ..| .|.|||.|  |.|| .. . .|  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----FKEEQAGILFAQILEGIEFLHSKNIIYRDLKPENILLDMNGYVKLADFGLSKVLKSKDQLNYTFCGSHEYMAPEMIQKKGHTF-AVDYYSLGVLLY
    | | .|  ...||....|..||..||.|||||||||||    .|..||||...|       .||||. .|||||..   |... ..| .|.|..||
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

ELVAGIPPFSSDNKTDLLEKALTKEVKFPPKQFSSQLQDFIKQLMIKDPTKRLGAKSGIS---EIRKHPWC
|...| |||.  .   ...| .           |... |||.... |||.||..|        .|..||| 
EMLCGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 15633.AA RSK 164-419 38 5.9e-97 328.4 In-house 1-278 (278) Show / Hide 
Range on Protein: 164-419
Range on HMM: 1-278/278
Sequence Identity: 38% (108 aa)

LKKIGLGGFSEVYLARRK---DNGQFVALKVIKKKTLIKKRR-KLYVYNEKNTMIALKDNPFIVQFFFAFQTREKLIFVLEYCPGGELFYHLNQERR---
||  | ||. .|.| |..   |.||  | ||.||...... .   ..  | | . . .  ||||. . |||| .||  ..|||.|||||.|| .|..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FKEEQAGILFAQILEGIEFLHSKNIIYRDLKPENILLDM---NGYVKLADFGLSKVLKSK-DQLNYTFCGSHEYMAPEMIQ----KKGHTFAVDYYSLGV
| |. | . .|.|   .|.||.. ||.|||||||||.|    .| .|| |||..| .. .  |. .|||...|||||||.     ..||. |.|..||||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LLYELVAGIPPFSS---DNKTDLLEKALTKE--VKFP-PKQFSSQLQDFIKQLMIKDPTKRLGA-KSGISEIRKHPWC
|.||. .| ||| .   .|. ..... ....  ...| ..  |   .|.|.... .|| ||||. .....||..||| 
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 15633.AA Ciliate-E2-Unclassified 161-419 30 1.6e-95 323.62 In-house 1-352 (352) Show / Hide 
Range on Protein: 161-419
Range on HMM: 1-352/352
Sequence Identity: 30% (108 aa)

FDVLKKIGLGGFSEVYLARRKDNGQFVALKVIKKKTLIKKRRKLYV---YNEKNTMIALK------------------DNPFIVQFFFAFQTREKLIFVL
. ..|.|| |||..||....|...|. |.| .||.  .|.. ....    ||...|  .|                  ..|||| .|..||.......|.
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYCPGGELFYHLNQE-----------------RRFKEEQAG-----ILFAQILEGIEFLHSKN-IIYRDLKPENILLDMNG---YVKLADFGLSKVLKS-
|||.||.|......                  ..| |.||       .|||||.|.|.||.|| ||.||.||||||.| ||   |.|..|||.|| ... 
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

--------------KDQLNYTFCGSHEYM----APEMIQKKGHT----FAVDYYSLGVLLYELVAGIPPFSSDNKTD----------------LLEKALT
              |.|. .||||. .||    |||..|....     ...|..||||.|||.. | .||.. |...                |... . 
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

KEVKFPP-------KQFSSQLQDFIKQLMIKDPTKRLGAKSGISEIRKHPWC
|...||.       |. | . .|||..|. |.. |... . ....| .||| 
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 15633.AA PKA 161-419 41 4.7e-95 322.1 In-house 1-263 (263) Show / Hide 
Range on Protein: 161-419
Range on HMM: 1-263/263
Sequence Identity: 41% (111 aa)

FDVLKKIGLGGFSEVYLARRKDNGQFVALKVIKKKTLIKKRRKLYVYNEKNTMIALKDNPFIV-QFFFAFQTREKLIFVLEYCPGGELFYHLNQERRFKE
|. .. .| | |  |.|.| |..|...|.|..|| . .. . .  | |||| . ..| .|||| .  . ||.. .| .|.||.||||.|..|  ..|| .
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIK-HPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSN

EQAGILFA-QILEGIEFLHSKNIIYRDLKPENILLDMNGYVKLADFGLSKVLKSKDQLNYTFCGSHEYMAPEMIQKK-GHTFAVDYYSLGVLLYELVAGI
 .| .  | ||   .|.|||.|||||||||||||.| ||..|..||| .| ...     .| ||  ||.|||.|| | ||  .||  .||.| ||..||.
PHAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD---RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGY

PPFSSD--NKTDLLEKALTKEVKFPPKQFSSQL---QDFIKQLMIKDPTKRLGAKS-GISEIRKHPWC
|||. .  .. .. || .  ..|||. .|.|..    |.||.|. .|.|||.| .. |.  |..|.| 
PPFYDHNRDPMQIYEKICNGKIKFPR-HFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase 15633.AA Ciliate-E2 161-419 24 1.3e-90 307.38 In-house 1-365 (365) Show / Hide 
Range on Protein: 161-419
Range on HMM: 1-365/365
Sequence Identity: 24% (95 aa)

FDVLKKIGLGGFSEVYLARR-----------------------KDNGQFVALKVIKKKTLIKKRRKLYVY----------NEKNTMIALKDNPFIVQFFF
....|||| |.|. ||....                       |......|.|..||. .. . ......          |||| .  . ..|.|.... 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNIL-EQLNHPNIIKMYE

AFQ--TREKLIFVLEYCPGGELFYHLN------------QERRFKEEQAGILFAQILE---------------GIEFLHSKN-IIYRDLKPENILLDMNG
.||  ..... .|.||| ||.||....            .  .|.|.... ...|||.               ..|.||||| ||.||.||||||.    
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

YVKLADFGLSKVLKSK-------------------------------DQLNYTFCGSHEYMAPEMIQKKG---------HTFAVDYYSLGVLLYELVAGI
 .|..|||||| .. .                               ... .|.||. .|||||....|.         .....|..||||.|||.. | 
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

PPFSSDNKTDLLEKALTKEVKFP-----------------PKQFSSQLQDFIKQ----LMIKDPTKRLGAKSGISEIRKHPWC
|||        ... . ....||                 .|. | . .|.||.    .. ||| ||..   |...| .||| 
PPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT---GWEQILNHPWF
Kinase 15633.AA CAMK 166-419 23 2.9e-90 291.0 In-house 1-425 (425) Show / Hide 
Range on Protein: 166-419
Range on HMM: 1-425/425
Sequence Identity: 23% (100 aa)

KIGLGGFSEVYLARRK-DNG-----------QFVALKVIKKKTLIK------------------------KRRKLY-VYNEKNTMIALK------DNPFI
..| |.|..|.|...| ..|           | || |.|.|| | .                        . ...  |..| . |  |.      | | |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQFFFAFQ------------TREK--------LIFVL---EYCPGGEL----FYHLNQE---------------RRFKEEQAGILFAQILEGIEFLHSKN
.... ...            | .|        ...|.   |||.||||    | .. .                .||.|..|  .| ||.......||.|
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IIYRDLKPENILLDMNG----------------Y-VKLADFGLSKVLKSK-----------------------DQLNYTFCGSHEYMA-PEMIQK-----
|. ||||||||||| |.                . .|..|||........                       .|. .||||. |||| ||....     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------KGHTFAVDYYSLGVLLYELVAGIPPFSSD-------------NKTDLLEKALTKEVKFPPKQFSS-----------------------QLQ
         .......|  |.||.|| .. | ||| .|             |  .|.|| .. .  |||..||                        . .
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DFIKQLMIKDPTKRLGAKSGISEIRKHPWC
|.|.... .||.||. ..    .. .||| 
DLIRKMLQVDPEKRMTIE----QCLNHPWM
Kinase 15633.AA Pkinase 161-419 31 3.6e-89 307.36 Pfam 1-293 (293) Show / Hide 
Range on Protein: 161-419
Range on HMM: 1-293/293
Sequence Identity: 31% (94 aa)

FDVLKKIGLGGFSEVYLARRKDNGQFVALKVIKKKTLIKKRRKLYVY-NEKNTMIALKDNPFIVQFFFAFQTREKLIFVLEYCPGG----ELFYHLN--Q
. ...||| |.|..||....|..|. ||.|.|||..  .. ..  .  .|   |  | . |.||... .|... .. .|.|||.||    .|| ..   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

ERRF--KEEQAGILFAQILEGIEFLHSKNIIYRDLKPENILLDMNGYV----KLADFGLSKVL-KSKDQLNYTFCGSHEYMAPEMIQ-KKGHTFAVDYYS
...|   |...   . |||.|.|..||..||.|||||||||.| ||..    |..||||.|..   ... ..||||. .||||| |.  .... .|| .|
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGVLLYELVAGIPPFSSD------NKTDLLEKALTKEVKFPPKQFS--------------------SQLQDFIKQLMIKDPTKRLGAKSGISEIRKHPWC
.|..|||.. | |||...      ..  .... . ....|.  . .                    . ..|||| .  |||.||..    . .| .||| 
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT----AEQILQHPWF
Kinase 15633.AA RSK-Unclassified 161-308 41 1.3e-56 176.08 In-house 1-149 (283) Show / Hide 
Range on Protein: 161-308
Range on HMM: 1-149/283
Sequence Identity: 41% (62 aa)

FDVLKKIGLGGFSEVYLARRKDNGQFVALKVIKKKTLIKKRRKLYVYNEKNTMIALKDNPFIVQFFFAFQTREKLIFVLEYCPGGELFYHLN--QERRFK
| . . || | | .||| |.||  |  |.|| .|. .|....  ||  |.| | |. . ||||. ...|||. .|  ..|||.||..| ||    |..| 
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIM-ATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFC

EEQAGILFAQILEGIEFLHSKNIIYRDLKPENILLDMNGYVKLADFGLSK
|... .  . .    | || . .|||||||.||.|.  | |.| ||.||.
EDDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSI
Kinase 15633.AA RSK-Unclassified 320-419 43 2.7e-43 133.53 In-house 182-283 (283) Show / Hide 
Range on Protein: 320-419
Range on HMM: 182-283/283
Sequence Identity: 43% (44 aa)

FCGSHEYMAPEMIQKKGHTFAVDYYSLGVLLYELVAGIPPFSSDNKTDLLEKALTKEVKFP-PKQFSSQLQDFIKQLMIKDPTKRLGAKSG-ISEIRKHP
|||. ||.|||||.  ||| ||| . ||...||.  |.||.  .||  . .  ....||||  .  | . .| || |. . | ||||.|.|   .|..||
FCGTEEYLAPEMIRRCGHTKAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHP

WC
  
FF
Kinase 15633.AA TyrKc 161-413 26 2.3e-17 58.01 SMART 1-280 (280) Show / Hide 
Range on Protein: 161-413
Range on HMM: 1-280/280
Sequence Identity: 26% (76 aa)

FDVLKKIGLGGFSEVYLARRKDNGQFVALKVIKKKTLIKKRRKLYVYNEKNTMIAL-KDNPFIVQFFFAFQTR-------EKLIFVLEYCPGGELFYHLN
   .||.| | | |||... |   . || |..|. .      .   ..| . |  | ...| ||... .  .        | |  |.||.|.| |  .| 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

QERR-FKEEQAGILFAQILEGIEFLHSKNIIYRDLKPENILLDMNGYVKLADFGLSKVLKSKDQL----NYTFC----GSHE-----YMAPEMIQKKGHT
  |. .. ..      || .| |.|||||.| |||   |.|.. |. || .|||||. ....||      |       |..       |||| |...  |
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

FAVDYYSLGVLLYELVA-GIPPFSS-----DNKTDLLEKALTKEVKFPPKQ--------FSSQLQDFIKQLMIKDPTKRLGAKSGISEI
.. | .| ||...|.   | .| .       . ....|.  . .   .|.          .. . . .||    || .|   .  ....
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 15633.AA Pkinase_Tyr 161-354 30 6e-12 41.08 Pfam 1-208 (270) Show / Hide 
Range on Protein: 161-354
Range on HMM: 1-208/270
Sequence Identity: 30% (64 aa)

FDVLKKIGLGGFSEVYLARRK----DNGQFVALKVIKKKTLIKK--RRKLYVYNEKNTMIALKDNPFIVQFFFAFQ-TREK--LIFVLEYCPGGELFYHL
   .||.| | | |||... |    .... || |..| ..  .   |...    | ..|  | ..| ||..  .    .|   .. |.||.|.| |  .|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR--EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

NQ----ERRFKEEQAGILFAQILEGIEFLHSKNIIYRDLKPENILLDMNGYVKLADFGLSKVLKSKDQLNYTFCG----SHEYMAPEMIQKKGHTFAVDY
 .    ..... ..     .|| .| |.|.|||.| |||   |.|.. |. || .||||.. . ..|.  |.  |        |||| |. .  | . | 
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTKSDV

YSLGVLLYELV
.| |||..|..
WSFGVLMWEIF