Gene 7480 (Tetrahymena)
7480
Sequence
Protein domains of 7480.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 7480.AA | AGC | 80-330 | 34 | 7.1e-188 | 491.09 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 80-330 Range on HMM: 1-395/395 Sequence Identity: 34% (137 aa) FRLEKVLGKGSFGKVMLVTHL------VEQKQYAMKVLLKKS---IKNERQKRHTLTE------------RQILEKID----------HPFIVK-LHYAF |.. ||.||||||||.|| . .|.|||||| || ||.... .||.|| |.||||.. |||||| |||.| FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF QTNEK--LYLVLDFMV---------GG-ELFHHLK---KSGKFSEEVTRFYASQ-------IVIGLEHLHQ-HKIIYRD-LKPENILLDSEGNLKLADF- |.... ||.|...| || |||.||. |.|.|.||..||||.. || .||.||. ..||.|| |||||||||..|..||.|| QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG ---------------------------------------------------------ENAPAHSLCG--TPEYLAPEIITSKVGHDKTVDWWS--FGALV ... ....|| ||||.||||. ..|..|||| .|.| LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----YGKACDWWSFGLGCLM YEMLTGSPPFYSNN----------KKQMLHNII------YKPIPIP----------KNLSDTAKSLLQQLLVVNPKNRLGYGDN-----GTSDVKNHPFF |||||| ||||..| ...| ..|. .....| ...|. ||.|...||...|..|||.|.| |....||||.| YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF |
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Kinase | 7480.AA | AktR | 80-330 | 54 | 1.1e-167 | 563.43 | In-house | 1-268 (268) | Show / Hide |
Range on Protein: 80-330 Range on HMM: 1-268/268 Sequence Identity: 54% (145 aa) FRLEKVLGKGSFGKVMLVTHL-VEQKQYAMKVLLKKSIKNERQKRHTLTERQILE-KIDHPFIVKLHYAFQTNEKLYLVLDFMVGGELFHHLKKSGKFSE |.. |.|||| ||||.||... .|||||||.. || |....|..||.|||.|.| ...|||||||||.|||.|||....... |||||.||||..|||| FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE EVTRFYASQIVIGLEHLHQH-KIIYRDLKPENILLDSEGNLKLADF----------ENAPAHSLCGTPEYLAPEIITSKVGHDKTVDWWSFGALVYEMLT |..|||..||...||.|||| .||||||||||||||..|..|..|| .. .|.|.||||||.|||.|| |.||.|.||||.||...|||.| EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT GSPPFYSNNKKQMLHNIIYKP---IPIPKNLSDTAKSLLQ-QLLVVNPKNRLGYGDNGTSDVKNHPFF | ||||..|..||...|..|. .|.|...|...|.|.| .|| ||..||||..||....|.||.| GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF |
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Kinase | 7480.AA | Akt | 80-330 | 50 | 7e-150 | 482.36 | In-house | 1-264 (264) | Show / Hide |
Range on Protein: 80-330 Range on HMM: 1-264/264 Sequence Identity: 50% (133 aa) FRLEKVLGKGSFGKVMLVTHLVEQKQY-AMKVLLKKSIKNERQKRHTLTERQILEKIDHPFIVKLHYAFQTNEKLYLVLDFMVGGELFHHLKKSGKFSEE |.. |||||||||||.|| || | ||||| |. | . .|..||.||| ||....|||||.|||.|||..|||.|.|.. ||||| ||.. ..|||. FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED VTRFYASQIVIGLEHLHQHKIIYRD-LKPENILLDSEGNLKLADF----EN-----APAHSLCGTPEYLAPEIITSKVGHDKTVDWWS-FGALVYEMLTG .|||...|. ..||||.. ||||| |||||||.|..|...|.|| || . ..|||||||||||. .||.|.||||. .|.. |||..| RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNG-NGHTKAVDWWGSLGCVMYEMMCG SPPFYSNNKKQMLHNIIYKPIPIP--KNLSDTAKSLLQQLLVVNPKNRLGYGDNGTSDVKNHPFF ||||. ...|| ..| ..|. .| ...|. .|.|. .|| .||.|||.| |.. ..|.||.| RPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF |
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Kinase | 7480.AA | SGK | 80-330 | 47 | 3.2e-145 | 451.71 | In-house | 1-283 (283) | Show / Hide |
Range on Protein: 80-330 Range on HMM: 1-283/283 Sequence Identity: 47% (136 aa) FRLEKVLGKGSFGKVMLVTHLVE------------------QKQYAMKVLLKKSIK-------NERQKRHTLTER-QILEKIDHPFIVKLHYAFQTNEKL |.. ||.||||||||..| | . .| |||||| |..| . . .|...|| || .. |||||.||||||| .|| FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL YLVLDFMVGGELFHHLKKSGKFSEEVTRFYASQIVIGLEHLHQHKIIYRDLKPENILLDSEGNLKLADF--------ENAPAHSLCGTPEYLAPEIITSK |.|.|.. |||.| ||.. ..|.| . ||||..|| ||.|| .||||||||||||||..|...| || .| . ||||||||||.. | YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLR-K VGHDKTVDWWSFGALVYEMLTGSPPFYSNNKKQMLHNIIYKPIPIPKNLSDTAKSLLQQLLVVNPKNRLGYGDNGTSDVKNHPFF .||.|||||. |.. |||..| |||||.||.|| ||| .|. ||.. | .|..|.|.|| .||.||| .. ..|||||| QPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGT-KRDFMEIKNHPFF |
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Kinase | 7480.AA | RSK | 84-330 | 45 | 3.9e-125 | 422.01 | In-house | 2-278 (278) | Show / Hide |
Range on Protein: 84-330 Range on HMM: 2-278/278 Sequence Identity: 45% (127 aa) KVLGKGSFGKVMLVTHL---VEQKQYAMKVLLKKSIKNERQ-KRHTLTERQILEKID-HPFIVKLHYAFQTNEKLYLVLDFMVGGELFHHLKKSGK---F ||||.|..||| |. ...|||||| |. |.. |||.|||.||| . |||||.|||||||..||||..... ||||| ||.| . | KVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGCF SEEVTRFYASQIVIGLEHLHQHKIIYRDLKPENILLDS---EGNLKLADF---------ENAPAHSLCGTPEYLAPEIIT---SKVGHDKTVDWWSFGAL ||. .||...|| .|||||..||.|||||||||.|. || .|| || .| .... |.| ||.|||... ..|||| .||||.|.| SEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVL VYEMLTGSPPFYS---NNKKQMLHNIIYKP--IPIP--KNLSDTAKSLLQQLLVVNPKNRLGYGDNGTSDVKNHPFF |||||| |||.. ||.|. . .| . ..| ..||..||.|....| ..|..|||.| ......|.||.| MYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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Kinase | 7480.AA | PKA | 80-330 | 46 | 5e-120 | 405.05 | In-house | 1-263 (263) | Show / Hide |
Range on Protein: 80-330 Range on HMM: 1-263/263 Sequence Identity: 46% (124 aa) FRLEKVLGKGSFGKVMLVTHLVEQKQYAMKVLLKKSIKNERQKRHTLTERQILEKIDHPFIV-KLHYAFQTNEKLYLVLDFMVGGELFHHLKKSGKFSEE | . ..||.||||.|||. | . ||||.| | |. ..|. |...|..|| |.||||| |. . ||.. .||.|... |||.|..| |||.||. FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP VTRFYAS-QIVIGLEHLHQHKIIYRDLKPENILLDSEGNLKLADF------ENAPAHSLCGTPEYLAPEIITSKVGHDKTVDWWSFGALVYEMLTGSPPF ...||| ||| || ||.. ||||||||||||.|..|..|..|| .. .|||||||||||||.|| || | ||||..| |.||||.| ||| HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD-RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPF YSN--NKKQMLHNIIYKPIPIPKNLSDTA---KSLLQQLLVVNPKNRLGYGDNGTSDVKNHPFF | . .. |. |. | | ... | |.|. .||.|... |.| .||. |.|||..| YDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF |
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Kinase | 7480.AA | p70 | 80-330 | 42 | 3.5e-110 | 372.37 | In-house | 1-299 (299) | Show / Hide |
Range on Protein: 80-330 Range on HMM: 1-299/299 Sequence Identity: 42% (126 aa) FRLEKVLGKGSFGKVMLVTHLV---EQKQYAMKVLLKKSI-KNERQKRHTL-------------------------TERQILEKIDHPFIVKLHYAFQTN | | |||||| .|||..| . | |||||| | .| |.. .|| || ||| . ||||..|||||||| FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNILEEVKHPFICDLHYAFQTN EKLYLVLDFMVGGELFHHLKKSGKFSEEVTRFYASQIVIGLEHLHQHKIIYRDLKPENILLDSEGNLKLADF--------ENAP----------AHSLCG .||||.|... ||||| ||.. | . |....||.| |.. ||||||| ||||||||||..|.. | ..| || . | |..|| GKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFCG TPEYLAPEIITSKVGHDKTVDWWSFGALVYEMLTGSPPFYSNNKKQMLHNIIYKP--IPIPKNLSDTAKSLLQQLLVVNPKNRLGYGDNGTSDVKNHPFF |.|| ||||.. ..||.. ||||| |.| | ||||.||| |.|. |. . .| |. .. |...|| .|. |.| | . |.. |||| TIEYMAPEILM-RCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQEHPFF |
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Kinase | 7480.AA | RSK | 80-330 | 39 | 4e-109 | 368.84 | In-house | 1-271 (271) | Show / Hide |
Range on Protein: 80-330 Range on HMM: 1-271/271 Sequence Identity: 39% (109 aa) FRLEKVLGKGSFGKVMLVTHL---VEQKQYAMKVLLKKSIKNERQKRHTLTERQILEKIDHPFIVKLHYAFQTNEKLYLVLDFMVGGELFHHLKKSGKFS . | ...|.|||.|| .. ...||||.. |..... . . .|| ||. ..|||||||||.||. .|.|...||| ||.|| .| | . || YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR-VCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMFS EEVTRFYASQIVIGLEHLHQHKIIYRDLKPENILLDSE----GNLKLADF--------ENAPAHSLCGTPEYLAPEIITSKVGHDKTVDWWSFGALVYEM |. .||.. | .|.||...|..|||||||||.|.| | .|..|| || . . |.| .|.|||.. .. |||. .||||||.| ||| EREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVL-KRQGHDQACDWWSFGVLMYEM LTGSPPFYSNNKKQMLHNIIYKPIPI-------PKNLSDTAKSLLQQLLVVNPKNRLGYGDNGTSDVKNHPFF ||| .||...... . .| . . . ..||.||.|| ..| ..| |||| | ||. ..|.||.| LTGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF |
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Kinase | 7480.AA | S_TKc | 80-330 | 36 | 1.8e-108 | 367.56 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 80-330 Range on HMM: 1-231/231 Sequence Identity: 36% (97 aa) FRLEKVLGKGSFGKVMLVTHLVEQKQYAMKVLLKKSIKNERQKRHTLTERQILEKIDHPFIVKLHYAFQTNEKLYLVLDFMVG--GELFHHLKKSGK--- ... ...|||.||||....| ....|.|.. .|.. |.|||.| .||.||||...||. ..||.|.... | |.||...|| |. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL ---FSEEVTRFYASQIVIGLEHLHQHKIIYRDLKPENILLDSEGNLKLADF----ENAPAHSLCGTPEYLAPEIITSKVGHDK-TVDWWSFGALVYEMLT |.| ..|||. ||. .||..|.|.||.|||||||||||. ..|..|| . ...||||.|.|||.. |..| .||||.| ..||||. RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLC GSPPFYSNNKKQMLHNIIYKPIPIPKNLSDTAKSLLQQLLVVNPKNRLGYGDNGT--SDVKNHPFF | |||. . ..|...| |. ||......|...|..|.. . . .|.|.||.| GYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | 7480.AA | Pkinase | 80-330 | 30 | 3.4e-96 | 330.67 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 80-330 Range on HMM: 1-293/293 Sequence Identity: 30% (91 aa) FRLEKVLGKGSFGKVMLVTHLVEQKQYAMKVLLKKSIKNERQKRHTL-TERQILEKIDHPFIVKLHYAFQTNEKLYLVLDFMVGG----ELFHHLK--KS .......|.||||.| . .| ..|..|.|.. |...| . ...|.. .| ||. ...||.||.|...|... ..|.|.... || .||.... .. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH GKF--SEEVTRFYASQIVIGLEHLHQHKIIYRDLKPENILLDSEGNL----KLADF--------ENAPAHSLCGTPEYLAPEIITSKVGHDKTVDWWSFG |.| ||.. .||. ||. |||..|...||.|||||||||.|..|.. |..|| | ....||||.|.|||.| . .... ||.||.| GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDYNNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCG ALVYEMLTGSPPFYSN------NKKQMLHNIIYKPIPIPKNLS---------------------DTAKSLLQQLLVVNPKNRLGYGDNGTSDVKNHPFF ..||||.| |||.. ...||. .| ..|.. . . ...|... .| ..|| |.. ....||.| CILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQILQHPWF |
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Kinase | 7480.AA | Ciliate-E2 | 80-330 | 24 | 1.8e-95 | 323.45 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 80-330 Range on HMM: 1-365/365 Sequence Identity: 24% (93 aa) FRLEKVLGKGSFGKVMLVTH-LVEQ----------------------KQYAMKVLLKKSIKNERQKRHTL----------TERQILEKIDHPFIVKLHYA . . |..|.|.||.| .... .| . |.||||.. |. |.. |. | . |..|||...||.|.|.... YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC FQ--TNEKLYLVLDFMVGGELFHHLK-------------------KSGKFSEEVTR-------FYASQIVIGLEHLHQHK-IIYRDLKPENILLDSEGNL || .....|||... ||.||...| . ......... ||. .|. .||.||. . ||.||.||||||. . FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I KLADFENA---------------------------------------PAHSLCGTPEYLAPEIITSKV--------GHDKTVDWWSFGALVYEMLTGSPP |..|| .. ....||||.|.||||. .| |.|. .|.||.| . ||||.| || KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP FYSNNKKQMLHNIIYKPIPIP------------------KNLSDTAKSLLQQ----LLVVNPKNRLGYGDNGTSDVKNHPFF | . .|. ..| .| |..|. .| |... .|...|..|.. | ....|||.| F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT----GWEQILNHPWF |
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Kinase | 7480.AA | RSK-Unclassified | 80-223 | 43 | 3.5e-63 | 197.1 | In-house | 1-146 (283) | Show / Hide |
Range on Protein: 80-223 Range on HMM: 1-146/283 Sequence Identity: 43% (64 aa) FRLEKVLGKGSFGKVMLVTHLVEQKQYAMKVLLKKSIKNERQKRHTLTERQILEKIDHPFIVKLHYAFQTNEKLYLVLDFMVGGELFHHLK--KSGKFSE | . .|.|.|||| || |. |||||| |. . . . .||. |. .|||||.| ..|||. .|||.... ||..| || |. .|.| FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE EVTRFYASQIVIGLEHLHQHKIIYRDLKPENILLDSEGNLKLADFE . ||||| ... ||.|| .|||||||.||.|. || .| ||. DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFD |
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Kinase | 7480.AA | RSK-Unclassified | 227-330 | 45 | 3.2e-42 | 130.07 | In-house | 179-283 (283) | Show / Hide |
Range on Protein: 227-330 Range on HMM: 179-283/283 Sequence Identity: 45% (48 aa) AHSLCGTPEYLAPEIITSKVGHDKTVDWWSFGALVYEMLTGSPPFYSNNKKQMLHNIIYKPIPIP--KNLSDTAKSLLQQLLVVNPKNRLGYGDNGTSDV . | ||| ||||||.| || | |||| | ..|||| | ||.| ||| . || ... .| . .| ....|. || || ||| . |. TNSFCGTEEYLAPEMIR-RCGHTKAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDI KNHPFF | |||| KRHPFF |
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Kinase | 7480.AA | TyrKc | 80-330 | 22 | 3.7e-14 | 6.24 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 80-330 Range on HMM: 1-280/280 Sequence Identity: 22% (67 aa) FRLEKVLGKGSFGKVMLVTHLVEQKQYAMKVLLKKSIKNERQKRHTLTERQILEKI--DHPFIVKLHYAFQTN-------EKLYLVLDFMVGGELFHHLK .|.|.|| | ||.|.. | | | |.| . . .. . | .|. |. .|| ||.|. . . | |..|. .| .| | ..|. ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR KSGK-FSEEVTRFYASQIVIGLEHLHQHKIIYRDLKPENILLDSEGNLKLADF---ENAPAH--------SLC-----GTPE-----YLAPEIITSKVGH |... .. . .. || | |.||....| ||| |.|..... | .|| . . |. .||| | .. KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK-F DKTVDWWSFGALVYEMLT-GSPPFYS-----NNKKQMLHNIIYK-PIPIPKN--------LSDTAKSLLQQLLVVNPKNRLGYGDNGTSDVKNHPFF | |||| . .|..| | .| . . ....... |.|.| .| .. .| .|..| . | .| TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-------HECF |
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Kinase | 7480.AA | Pkinase_Tyr | 80-222 | 25 | 1.7e-13 | 46.35 | Pfam | 1-155 (270) | Show / Hide |
Range on Protein: 80-222 Range on HMM: 1-155/270 Sequence Identity: 25% (40 aa) FRLEKVLGKGSFGKVMLVTHLVEQKQYAMKVLLKKS--IKNERQ--KRHTLTERQILEKI-DHPFIVKLHYAFQ-TNEK--LYLVLDFMVGGELFHHLKK .. |.||.|.||.|.. | .... ..| |. ..| .. . | .|. .. .|| ||.|. . | .|.|. .| .| | ..|.| ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK ----SGKFSEEVTRFYASQIVIGLEHLHQHKIIYRDLKPENILLDSEGNLKLADF .... . .. || |.|.|.....| ||| |.|..... | .|| HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDF |
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Kinase | 7480.AA | S_TK_X | 331-390 | 18 | 1.5e-05 | 24.58 | SMART | 1-79 (79) | Show / Hide |
Range on Protein: 331-390 Range on HMM: 1-79/79 Sequence Identity: 18% (15 aa) ATINWEAMKE--RKIKTPLNINVT----DERDTKYFDPYILKQQAVDTPVSY----NQDLFK---------FSQFTYNK . |.|.. ..|. | ... ...||..||| ......||.. ... . | .|||. RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF |
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Kinase | 7480.AA | Pkinase_Tyr | 255-283 | 32 | 0.100722 | 6.46 | Pfam | 198-228 (270) | Show / Hide |
Range on Protein: 255-283 Range on HMM: 198-228/270 Sequence Identity: 32% (10 aa) WSFGALVYEMLT-GSPP-FYSNNKKQMLHNI |||| | .|..| | | .. .... | WSFGVLMWEIFTYGEQPTYPGMSNEEVYEYI |