7480

Species: Tetrahymena
Alias: 204, 3814.m00962, 87.m00260, TTHERM_00624920, PreTt07480, 7480
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: AGC
Family: AktR

Sequence

Name Sequence Type Origin Length Description Download
7480.AA Protein None 796 None Fasta, JSON
7480.kin_dom Protein Kinase Domain None 251 None Fasta, JSON
7480.NA RNA None 2391 None Fasta, JSON

Protein domain

Protein domains of 7480.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 7480.AA AGC 80-330 34 7.1e-188 491.09 In-house 1-395 (395) Show / Hide
Range on Protein: 80-330
Range on HMM: 1-395/395
Sequence Identity: 34% (137 aa)

FRLEKVLGKGSFGKVMLVTHL------VEQKQYAMKVLLKKS---IKNERQKRHTLTE------------RQILEKID----------HPFIVK-LHYAF
|.. ||.||||||||.|| .         .|.|||||| ||    ||.... .||.||            |.||||..          |||||| |||.|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTNEK--LYLVLDFMV---------GG-ELFHHLK---KSGKFSEEVTRFYASQ-------IVIGLEHLHQ-HKIIYRD-LKPENILLDSEGNLKLADF-
|....  ||.|...|          || |||.||.   |.|.|.||..||||..       || .||.||. ..||.|| |||||||||..|..||.|| 
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

---------------------------------------------------------ENAPAHSLCG--TPEYLAPEIITSKVGHDKTVDWWS--FGALV
                                                         ... ....||  ||||.||||.     ..|..||||  .|.| 
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----YGKACDWWSFGLGCLM

YEMLTGSPPFYSNN----------KKQMLHNII------YKPIPIP----------KNLSDTAKSLLQQLLVVNPKNRLGYGDN-----GTSDVKNHPFF
|||||| ||||..|          ...| ..|.       .....|          ...|. ||.|...||...|..|||.|.|     |....||||.|
YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF





Kinase 7480.AA AktR 80-330 54 1.1e-167 563.43 In-house 1-268 (268) Show / Hide
Range on Protein: 80-330
Range on HMM: 1-268/268
Sequence Identity: 54% (145 aa)

FRLEKVLGKGSFGKVMLVTHL-VEQKQYAMKVLLKKSIKNERQKRHTLTERQILE-KIDHPFIVKLHYAFQTNEKLYLVLDFMVGGELFHHLKKSGKFSE
|.. |.|||| ||||.||...  .|||||||.. || |....|..||.|||.|.| ...|||||||||.|||.|||....... |||||.||||..||||
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

EVTRFYASQIVIGLEHLHQH-KIIYRDLKPENILLDSEGNLKLADF----------ENAPAHSLCGTPEYLAPEIITSKVGHDKTVDWWSFGALVYEMLT
|..|||..||...||.|||| .||||||||||||||..|..|..||          .. .|.|.||||||.|||.|| |.||.|.||||.||...|||.|
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GSPPFYSNNKKQMLHNIIYKP---IPIPKNLSDTAKSLLQ-QLLVVNPKNRLGYGDNGTSDVKNHPFF
| ||||..|..||...|..|.   .|.|...|...|.|.| .||  ||..||||..||....|.||.|
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF

Kinase 7480.AA Akt 80-330 50 7e-150 482.36 In-house 1-264 (264) Show / Hide
Range on Protein: 80-330
Range on HMM: 1-264/264
Sequence Identity: 50% (133 aa)

FRLEKVLGKGSFGKVMLVTHLVEQKQY-AMKVLLKKSIKNERQKRHTLTERQILEKIDHPFIVKLHYAFQTNEKLYLVLDFMVGGELFHHLKKSGKFSEE
|.. |||||||||||.||     || | ||||| |. | . .|..||.||| ||....|||||.|||.|||..|||.|.|.. ||||| ||.. ..|||.
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

VTRFYASQIVIGLEHLHQHKIIYRD-LKPENILLDSEGNLKLADF----EN-----APAHSLCGTPEYLAPEIITSKVGHDKTVDWWS-FGALVYEMLTG
 .|||...|. ..||||.. ||||| |||||||.|..|...|.||    ||       . ..|||||||||||.   .||.|.||||. .|.. |||..|
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNG-NGHTKAVDWWGSLGCVMYEMMCG

SPPFYSNNKKQMLHNIIYKPIPIP--KNLSDTAKSLLQQLLVVNPKNRLGYGDNGTSDVKNHPFF
 ||||. ...|| ..| ..|. .|  ...|. .|.|. .||  .||.|||.| |.. ..|.||.|
RPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF

Kinase 7480.AA SGK 80-330 47 3.2e-145 451.71 In-house 1-283 (283) Show / Hide
Range on Protein: 80-330
Range on HMM: 1-283/283
Sequence Identity: 47% (136 aa)

FRLEKVLGKGSFGKVMLVTHLVE------------------QKQYAMKVLLKKSIK-------NERQKRHTLTER-QILEKIDHPFIVKLHYAFQTNEKL
|.. ||.||||||||..| |  .                  .| |||||| |..|        .  . .|...||  || .. |||||.||||||| .||
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YLVLDFMVGGELFHHLKKSGKFSEEVTRFYASQIVIGLEHLHQHKIIYRDLKPENILLDSEGNLKLADF--------ENAPAHSLCGTPEYLAPEIITSK
|.|.|.. |||.| ||.. ..|.| . ||||..||  ||.||  .||||||||||||||..|...| ||        .|    . ||||||||||..  |
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLR-K

VGHDKTVDWWSFGALVYEMLTGSPPFYSNNKKQMLHNIIYKPIPIPKNLSDTAKSLLQQLLVVNPKNRLGYGDNGTSDVKNHPFF
 .||.|||||. |.. |||..| |||||.||.||  ||| .|. ||.. | .|..|.|.||  .||.|||   ..  ..||||||
QPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGT-KRDFMEIKNHPFF

Kinase 7480.AA RSK 84-330 45 3.9e-125 422.01 In-house 2-278 (278) Show / Hide
Range on Protein: 84-330
Range on HMM: 2-278/278
Sequence Identity: 45% (127 aa)

KVLGKGSFGKVMLVTHL---VEQKQYAMKVLLKKSIKNERQ-KRHTLTERQILEKID-HPFIVKLHYAFQTNEKLYLVLDFMVGGELFHHLKKSGK---F
||||.|..||| |.        ...|||||| |. |..     |||.|||.||| .  |||||.|||||||..||||..... ||||| ||.| .    |
KVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGCF

SEEVTRFYASQIVIGLEHLHQHKIIYRDLKPENILLDS---EGNLKLADF---------ENAPAHSLCGTPEYLAPEIIT---SKVGHDKTVDWWSFGAL
||.  .||...||  .|||||..||.|||||||||.|.   || .|| ||         .| .... |.| ||.|||...    ..|||| .||||.|.|
SEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVL

VYEMLTGSPPFYS---NNKKQMLHNIIYKP--IPIP--KNLSDTAKSLLQQLLVVNPKNRLGYGDNGTSDVKNHPFF
 |||||| |||..   ||.|. . .|  .    ..|  ..||..||.|....| ..|..|||.| ......|.||.|
MYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF

Kinase 7480.AA PKA 80-330 46 5e-120 405.05 In-house 1-263 (263) Show / Hide
Range on Protein: 80-330
Range on HMM: 1-263/263
Sequence Identity: 46% (124 aa)

FRLEKVLGKGSFGKVMLVTHLVEQKQYAMKVLLKKSIKNERQKRHTLTERQILEKIDHPFIV-KLHYAFQTNEKLYLVLDFMVGGELFHHLKKSGKFSEE
| . ..||.||||.|||. |    . ||||.| |  |. ..|. |...|..||  |.||||| |. . ||.. .||.|...  |||.|..| |||.||. 
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

VTRFYAS-QIVIGLEHLHQHKIIYRDLKPENILLDSEGNLKLADF------ENAPAHSLCGTPEYLAPEIITSKVGHDKTVDWWSFGALVYEMLTGSPPF
...|||  |||  || ||.. ||||||||||||.|..|..|..||      ..    .|||||||||||||.|| || | ||||..| |.||||.| |||
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD-RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPF

YSN--NKKQMLHNIIYKPIPIPKNLSDTA---KSLLQQLLVVNPKNRLGYGDNGTSDVKNHPFF
| .  .. |.   |.   |  | ...  |   |.|. .||.|... |.|  .||. |.|||..|
YDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF

Kinase 7480.AA p70 80-330 42 3.5e-110 372.37 In-house 1-299 (299) Show / Hide
Range on Protein: 80-330
Range on HMM: 1-299/299
Sequence Identity: 42% (126 aa)

FRLEKVLGKGSFGKVMLVTHLV---EQKQYAMKVLLKKSI-KNERQKRHTL-------------------------TERQILEKIDHPFIVKLHYAFQTN
| | |||||| .|||..|       . | |||||| | .|  |..  .||                           || ||| . ||||..||||||||
FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNILEEVKHPFICDLHYAFQTN

EKLYLVLDFMVGGELFHHLKKSGKFSEEVTRFYASQIVIGLEHLHQHKIIYRDLKPENILLDSEGNLKLADF--------ENAP----------AHSLCG
.||||.|... ||||| ||.. | . |....||.| |.. ||||||| ||||||||||..|.. | ..| ||        . |            |..||
GKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFCG

TPEYLAPEIITSKVGHDKTVDWWSFGALVYEMLTGSPPFYSNNKKQMLHNIIYKP--IPIPKNLSDTAKSLLQQLLVVNPKNRLGYGDNGTSDVKNHPFF
|.|| ||||.. ..||.. ||||| |.| | ||||.|||   |.|.    |.     . .|  |.  .. |...||  .|. |.| | .   |.. ||||
TIEYMAPEILM-RCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQEHPFF





Kinase 7480.AA RSK 80-330 39 4e-109 368.84 In-house 1-271 (271) Show / Hide
Range on Protein: 80-330
Range on HMM: 1-271/271
Sequence Identity: 39% (109 aa)

FRLEKVLGKGSFGKVMLVTHL---VEQKQYAMKVLLKKSIKNERQKRHTLTERQILEKIDHPFIVKLHYAFQTNEKLYLVLDFMVGGELFHHLKKSGKFS
. | ...|.|||.|| ..        ...||||.. |.....  .   . .|| ||. ..|||||||||.||. .|.|...||| ||.|| .| | . ||
YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR-VCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMFS

EEVTRFYASQIVIGLEHLHQHKIIYRDLKPENILLDSE----GNLKLADF--------ENAPAHSLCGTPEYLAPEIITSKVGHDKTVDWWSFGALVYEM
|.  .||.. |   .|.||...|..|||||||||.|.|    | .|..||        ||  . . |.| .|.|||.. .. |||. .||||||.| |||
EREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVL-KRQGHDQACDWWSFGVLMYEM

LTGSPPFYSNNKKQMLHNIIYKPIPI-------PKNLSDTAKSLLQQLLVVNPKNRLGYGDNGTSDVKNHPFF
||| .||...... .  .|   .  .       . ..||.||.|| ..| ..| |||| | ||. ..|.||.|
LTGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF

Kinase 7480.AA S_TKc 80-330 36 1.8e-108 367.56 SMART 1-231 (231) Show / Hide
Range on Protein: 80-330
Range on HMM: 1-231/231
Sequence Identity: 36% (97 aa)

FRLEKVLGKGSFGKVMLVTHLVEQKQYAMKVLLKKSIKNERQKRHTLTERQILEKIDHPFIVKLHYAFQTNEKLYLVLDFMVG--GELFHHLKKSGK---
... ...|||.||||....|   ....|.|..           .|.. |.|||.| .||.||||...||. ..||.|.... |  |.||...|| |.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FSEEVTRFYASQIVIGLEHLHQHKIIYRDLKPENILLDSEGNLKLADF----ENAPAHSLCGTPEYLAPEIITSKVGHDK-TVDWWSFGALVYEMLT
   |.| ..|||. ||. .||..|.|.||.|||||||||||.  ..|..||    .    ...||||.|.|||..    |..|  .||||.| ..||||.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLC

GSPPFYSNNKKQMLHNIIYKPIPIPKNLSDTAKSLLQQLLVVNPKNRLGYGDNGT--SDVKNHPFF
| |||.  . ..|...|           |. ||......|...|..|..  .  .  .|.|.||.|
GYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 7480.AA Pkinase 80-330 30 3.4e-96 330.67 Pfam 1-293 (293) Show / Hide
Range on Protein: 80-330
Range on HMM: 1-293/293
Sequence Identity: 30% (91 aa)

FRLEKVLGKGSFGKVMLVTHLVEQKQYAMKVLLKKSIKNERQKRHTL-TERQILEKIDHPFIVKLHYAFQTNEKLYLVLDFMVGG----ELFHHLK--KS
.......|.||||.| . .|  ..|..|.|.. |...| . ...|.. .| ||. ...||.||.|...|... ..|.|.... ||    .||....  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GKF--SEEVTRFYASQIVIGLEHLHQHKIIYRDLKPENILLDSEGNL----KLADF--------ENAPAHSLCGTPEYLAPEIITSKVGHDKTVDWWSFG
|.|  ||.. .||. ||. |||..|...||.|||||||||.|..|..    |..||         |  ....||||.|.|||.| .  .... ||.||.|
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDYNNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCG

ALVYEMLTGSPPFYSN------NKKQMLHNIIYKPIPIPKNLS---------------------DTAKSLLQQLLVVNPKNRLGYGDNGTSDVKNHPFF
 ..||||.| |||..       ...||. .| ..|.. .   .                     ...|...  .| ..|| |..       ....||.|
CILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQILQHPWF

Kinase 7480.AA Ciliate-E2 80-330 24 1.8e-95 323.45 In-house 1-365 (365) Show / Hide
Range on Protein: 80-330
Range on HMM: 1-365/365
Sequence Identity: 24% (93 aa)

FRLEKVLGKGSFGKVMLVTH-LVEQ----------------------KQYAMKVLLKKSIKNERQKRHTL----------TERQILEKIDHPFIVKLHYA
. . |..|.|.||.| .... .| .                      |.||||.. |. |..  |. | .           |..|||...||.|.|....
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FQ--TNEKLYLVLDFMVGGELFHHLK-------------------KSGKFSEEVTR-------FYASQIVIGLEHLHQHK-IIYRDLKPENILLDSEGNL
||  .....|||...  ||.||...|                   . .........       ||. .|. .||.||. . ||.||.||||||.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLADFENA---------------------------------------PAHSLCGTPEYLAPEIITSKV--------GHDKTVDWWSFGALVYEMLTGSPP
|..|| ..                                        ....||||.|.||||. .|         |.|. .|.||.| . ||||.| ||
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FYSNNKKQMLHNIIYKPIPIP------------------KNLSDTAKSLLQQ----LLVVNPKNRLGYGDNGTSDVKNHPFF
|        . .|. ..| .|                  |..|. .| |...    .|...|..|..    | ....|||.|
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT----GWEQILNHPWF

Kinase 7480.AA RSK-Unclassified 80-223 43 3.5e-63 197.1 In-house 1-146 (283) Show / Hide
Range on Protein: 80-223
Range on HMM: 1-146/283
Sequence Identity: 43% (64 aa)

FRLEKVLGKGSFGKVMLVTHLVEQKQYAMKVLLKKSIKNERQKRHTLTERQILEKIDHPFIVKLHYAFQTNEKLYLVLDFMVGGELFHHLK--KSGKFSE
|   . .|.|.|||| ||     |. |||||| |. .   .  .  .||. |.   .|||||.| ..|||. .|||....  ||..| ||   |. .|.|
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE

EVTRFYASQIVIGLEHLHQHKIIYRDLKPENILLDSEGNLKLADFE
.  ||||| ... ||.||   .|||||||.||.|. ||  .| ||.
DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFD

Kinase 7480.AA RSK-Unclassified 227-330 45 3.2e-42 130.07 In-house 179-283 (283) Show / Hide
Range on Protein: 227-330
Range on HMM: 179-283/283
Sequence Identity: 45% (48 aa)

AHSLCGTPEYLAPEIITSKVGHDKTVDWWSFGALVYEMLTGSPPFYSNNKKQMLHNIIYKPIPIP--KNLSDTAKSLLQQLLVVNPKNRLGYGDNGTSDV
. | ||| ||||||.|    || | ||||  | ..|||| | ||.| |||  .  ||  ... .|  . .| ....|.  ||  ||  ||| .     |.
TNSFCGTEEYLAPEMIR-RCGHTKAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDI

KNHPFF
| ||||
KRHPFF

Kinase 7480.AA TyrKc 80-330 22 3.7e-14 6.24 SMART 1-280 (280) Show / Hide
Range on Protein: 80-330
Range on HMM: 1-280/280
Sequence Identity: 22% (67 aa)

FRLEKVLGKGSFGKVMLVTHLVEQKQYAMKVLLKKSIKNERQKRHTLTERQILEKI--DHPFIVKLHYAFQTN-------EKLYLVLDFMVGGELFHHLK
 .|.|.|| | ||.|.. |      | | |.| . .      ..  . | .|. |.  .|| ||.|. .  .        | |..|. .| .| | ..|.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KSGK-FSEEVTRFYASQIVIGLEHLHQHKIIYRDLKPENILLDSEGNLKLADF---ENAPAH--------SLC-----GTPE-----YLAPEIITSKVGH
|... .. .    .. ||  | |.||....| |||   |.|.....  | .||    .   .                |.        .||| |  ..  
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK-F

DKTVDWWSFGALVYEMLT-GSPPFYS-----NNKKQMLHNIIYK-PIPIPKN--------LSDTAKSLLQQLLVVNPKNRLGYGDNGTSDVKNHPFF
    | |||| . .|..| | .| .       . .......      |.|.|         .|   .. .|    .|..|    .        | .|
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-------HECF

Kinase 7480.AA Pkinase_Tyr 80-222 25 1.7e-13 46.35 Pfam 1-155 (270) Show / Hide
Range on Protein: 80-222
Range on HMM: 1-155/270
Sequence Identity: 25% (40 aa)

FRLEKVLGKGSFGKVMLVTHLVEQKQYAMKVLLKKS--IKNERQ--KRHTLTERQILEKI-DHPFIVKLHYAFQ-TNEK--LYLVLDFMVGGELFHHLKK
 .. |.||.|.||.|.. |   ....  ..|  |.      ..|  ..  . | .|. .. .|| ||.|. .     |   .|.|. .| .| | ..|.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

----SGKFSEEVTRFYASQIVIGLEHLHQHKIIYRDLKPENILLDSEGNLKLADF
     .... .    .. ||  |.|.|.....| |||   |.|.....  | .||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDF

Kinase 7480.AA S_TK_X 331-390 18 1.5e-05 24.58 SMART 1-79 (79) Show / Hide
Range on Protein: 331-390
Range on HMM: 1-79/79
Sequence Identity: 18% (15 aa)

ATINWEAMKE--RKIKTPLNINVT----DERDTKYFDPYILKQQAVDTPVSY----NQDLFK---------FSQFTYNK
. |.|..     ..|. |   ...    ...||..|||   ......||..     ...  .         | .|||. 
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF

Kinase 7480.AA Pkinase_Tyr 255-283 32 0.100722 6.46 Pfam 198-228 (270) Show / Hide
Range on Protein: 255-283
Range on HMM: 198-228/270
Sequence Identity: 32% (10 aa)

WSFGALVYEMLT-GSPP-FYSNNKKQMLHNI
|||| | .|..| |  | ..     .... |
WSFGVLMWEIFTYGEQPTYPGMSNEEVYEYI