Gene 19367 (Tetrahymena)

19367

Species: Tetrahymena
Alias: TTHERM_00301710, 19367, 594, 28.m00326, 3691.m00143, PreTt19367
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: CAMK
Family: CAMK-Tt

Sequence

Name Sequence Type Origin Length Description Download
19367.AA Protein None 711 None Fasta, JSON
19367.kin_dom Protein Kinase Domain None 267 None Fasta, JSON
19367.NA RNA None 2136 None Fasta, JSON

Protein domain

Protein domains of 19367.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 19367.AA CAMK-Tt 152-319 67 1.4e-130 440.12 In-house 225-396 (396) Show / Hide 
Range on Protein: 152-319
Range on HMM: 225-396/396
Sequence Identity: 67% (117 aa)

VAISIFKQILEAIDYLHENMVCHRDLKPNNILCNEDGTCVKITDFNVSKFAHYDNAHKKASTMEGRKQVLMWTYTGTVAYSAPEIFDGDS-YDETVDMWS
||..||||||.||.|.|||.||||||||||||||||||||||||||||||.......||...|.. ....|||||||||.||||||..|. ||||.||||
VASKIFKQILDAIKYMHENYVCHRDLKPNNILCNEDGTCVKITDFNVSKFCDHYKNYKKDNLMNH-QNIKMWTYTGTVAFSAPEIFNEDCCYDETIDMWS

AGAVLYTMLAGYQPFEEEYVQDLIAKIKSADYTFP----KNISENAQDLIKKCLQIDPEKRIKPTEALAHPWI
||..|||||.|..||..|||.|||.||..|||.||    ..|||.|.|||||||.|.||.||||...|.||||
AGCILYTMLCGQEPFQAEYVHDLIKKICQADYNFPSHVWQHISEEAKDLIKKCLTINPEQRIKPDQMLQHPWI
Kinase 19367.AA CAMK 58-319 23 9.5e-101 325.4 In-house 1-425 (425) Show / Hide 
Range on Protein: 58-319
Range on HMM: 1-425/425
Sequence Identity: 23% (102 aa)

ILGEGCVGLVKKVERLSDG------------KIFASKMVKTKD---------------------------EEEVVLNVIREFKNLRE-------LNHPNI
.||.|  | ||.... ...            . .| |....|                            ...   || || . ..        |.||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKVYELYVD----------ETKGR--------IYTIM---ELVEAKEM----FDVISKLGQ---------------YSESVAISIFKQILEAIDYLHENM
.| || | |          ||  .        .| .|   |...  |.    || | . |.               ..|. |  .|.||..|..|.|.. 
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

VCHRDLKPNNILCNEDG----------------TCVKITDFNVSKFAHYDNAHKKASTMEGRKQV-----------LMWTYTGTVAYSA-PEIFDG----
..|||||| |||.....                  .||.||  ...   ..  .. | ..|.  .           .|.|. || .| | ||.. |    
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-MHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC

----------DSYDETVDMWSAGAVLYTMLAGYQPFEEE-------------YVQDLIAKIKSADYTFP----------------KNISEN--------A
          . |.. .||||.| .||.|| || ||...               ..|  ||....|.||                ..||..        .
NMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQEC

QDLIKKCLQIDPEKRIKPTEALAHPWI
.|||.|.|| |||||.. ...|.|||.
KDLIRKMLQVDPEKRMTIEQCLNHPWM
S_TKc 19367.AA S_TKc 53-319 32 2.2e-91 310.82 SMART 1-231 (231) Show / Hide 
Range on Protein: 53-319
Range on HMM: 1-231/231
Sequence Identity: 32% (93 aa)

YREIEILGEGCVGLVKKVERLSDGKIFASKMVKTKDEEEVVLNVIREFKNLRELNHPNIVKVYELYVDETKGRIYTIMELVEA--KEMFDVISKLGQ---
|. ....|.|  | |.|.   ..|.|.| |..|         ...|| . |.. .|||||| |. ..|   ...| .||...    ..||.| | |    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---YSESVAISIFKQILEAIDYLHENMVCHRDLKPNNILCNEDGTCVKITDFNVSKFAHYDNAHKKASTMEGRKQVLMWTYTGTVAYSAPEIFDGDSYDE
   ..| .| ....||..|..|.|.. ..|||||| |||..|   ..||.|| ....                      |. ||  | |||..   .|. 
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL--------------------TTFCGTPWYMAPEVL---GYGK

-TVDMWSAGAVLYTMLAGYQPFEEEYVQDLIAKIKSADYTFPKNISENAQDLIKKCLQIDPEKRIKPTEALA-------HPWI
  .|.|| | .|| ||.|| ||.   .| .. ||.          |. | |.|.|||| |||||.   |||.       |||.
CKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase 19367.AA Pkinase 53-319 31 7.5e-85 292.99 Pfam 1-293 (293) Show / Hide 
Range on Protein: 53-319
Range on HMM: 1-293/293
Sequence Identity: 31% (98 aa)

YREIEILGEGCVGLVKKVERLSDGKIFASKMVKTKDEEEVVL-NVIR--EFKNLRELNHPNIVKVYELYVDETKGRIYTIMELVEAK----EMFDVIS--
|. ....|.|  | |.|  . ..|||.| | .| ..|.. .. . .|  | . ...|||||||. |. . |  |..|| .||..|      . ||.||  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYISTW

KLGQY--SESVAISIFKQILEAIDYLHENMVCHRDLKPNNILCNEDGTC---VKITDFNVSKFAHYDNAHKKASTMEGRKQVLMWTYTGTVAYSAPEIFD
. | .  || .......|||....|.|.. ..|||||| |||....|..   |||.|| ..|..               ... |.|..||  | |||.  
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD------------Y-NNS-MTTFCGTPWYMAPEVIR

-GDSYDETVDMWSAGAVLYTMLAGYQPFEEE------YVQDLIAKIKSADYTFPKNIS---------------------ENAQDLIKKCLQIDPEKRIKP
 |  |.  |||||.| .|| || |. || ..        . .|..|..... |.   .                     |...|.||.||. ||.||. .
GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTA

TEALAHPWI
...| |||.
EQILQHPWF
Kinase 19367.AA Ciliate-E2 53-319 27 1e-83 284.47 In-house 1-365 (365) Show / Hide 
Range on Protein: 53-319
Range on HMM: 1-365/365
Sequence Identity: 27% (106 aa)

YREIEILGEGCVG-----LVKKVERLS------------------DGKIFASKMVKTKDEEEV--VLNVIREFK----------NLRELNHPNIVKVYEL
|  |...|.|. |      |.|| ...                  ..||.| |..| .. |..  .....|| .          .|..||||||.| || 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YVDETKGRIYTIMELVEAKEMFDVISKL-----------GQYSESVAISIFKQILE---------------AIDYLHENM-VCHRDLKPNNILCNEDGTC
. ....  || .||... ...|| | .            ....|  .. |.||||.               |. |||..  ..|||.||.|||       
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

VKITDFNVSKFAHYDNAHKK-----ASTMEGR--------------KQVLMWTYTGTVAYSAPEIFDGDS---------YDETVDMWSAGAVLYTMLAGY
.||.||  ||... ||  .         |. .              .| . .|. ||  | ||||. | .         ||. .|.||.| .|| || |.
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

QPFEEEYVQDLIAKIKSADYTFP------------------KNISENAQDLIKK----CLQIDPEKRIK-PTEALAHPWI
 ||        . .||  .. ||                  |..|....|||||    .|| ||||||  . ..| |||.
PPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 19367.AA CAMK1 53-319 34 5.1e-78 226.37 In-house 1-276 (276) Show / Hide 
Range on Protein: 53-319
Range on HMM: 1-276/276
Sequence Identity: 34% (102 aa)

YREIEILGEGCVGLVKKVERLS---DGKIFASKMVK-TK-DEEEVV---LNVIREFKNLR---ELNHPNIVKVYELYVDETKGRIYTIMELVEAKEMFDV
|  ....|.|  . |..... .   .|| .| |. .  |  ... .    .. .|   ..   ...||||.| || |  |..  .| .||||   | || 
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWY--ESDNHFYLVMELVTGGELFDR

ISKLGQYSESVAISIFKQILEAIDYLHENMVCHRDLKPNNILCNEDGTC--VK--ITDFNVSKFAHYD-NAHKKASTMEGRKQVLMWTYTGTVAYSAPEI
| . |.|.|  |  | ||||.|. |.|.. ..|||||| |.|.        .|  | ||  ||.   | |              || |  ||  | |||.
IVEKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDEN--------------LMKTACGTPGYVAPEV

FDG---DSYDETVDMWSAGAVLYTMLAGYQPFEEEY-VQDLIAKIKSADYTFPKN----ISEN-AQDLIKKCLQIDPEKRIKPTEALAHPWI
. .   . || ..||||.| ..|..| ||.|| .|   . | .|||...|.||..    ||.  | |.||. |  ||.||.  ...|.||||
LECKKDKPYDKACDMWSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase 19367.AA Ciliate-E2-Unclassified 53-319 27 1.2e-75 257.61 In-house 1-352 (352) Show / Hide 
Range on Protein: 53-319
Range on HMM: 1-352/352
Sequence Identity: 27% (98 aa)

YREIEILGEGCVGLVKKVERLSDG-----------KIFASKMVKTKDEEEVVLNVIREFK-NLRE----------LNHPNIVKVYELYVDETKGRIYTIM
|. |...|.|. | |.|... ...           .|...| ...|||.   .. . . | .  .          ||||....|...|....|  || .|
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

ELVEAKEMFDVISKLGQ-----------------YSESVAI-----SIFKQILEAIDYLHEN-MVCHRDLKPNNILCNEDGT--CVKITDFNVSKFAHYD
|..| ..... |.| ..                  .|  |.      .|.|||....|||.. ...|||.||.||| ...|   ..||.||  ||.  ..
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

NAHK---KASTMEGRKQVL----MWTYTGTVAYS----APEIFDGDSYDET----VDMWSAGAVLYTMLAGYQPFE-EEYVQ---------------DLI
|  .   .      ..|..    ||| .||  |     |||...|  ||..    .|.|| | .|| || || ||. . . |                |.
NNCDTNQQ-----QKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLY

AKIKSADYTFPK--------NISENAQDLIK----KCLQIDPEKRIKPTEALAHPWI
 .||  .. |||        ..|..|.|.|.    |.|. .|.||| . ..| |||.
QNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 19367.AA Ciliate-E2a 53-319 31 3.1e-75 220.92 In-house 1-275 (275) Show / Hide 
Range on Protein: 53-319
Range on HMM: 1-275/275
Sequence Identity: 31% (90 aa)

YREIEILGEGCVGLVKKVERLSDGKIFASKMVKTKDEEEV--VLNVIREFKNLRELNHPNIVKVYELYVDETKGRIYTIMELVEAKEMFDVISKLGQYSE
|. | ..|.|. | |...... .|| || | .. |....     ....| . .|.|.|||| | || | ||.   .| .||..| .|..| |.. ... |
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENN--YYLVMEYCEGGELYDKIKQCKRFFE

S--VAISIFKQIL-EAIDYLHENMVCHRDLKPNNILCN---EDG---TCVKITDFNVSKFAHYDNAHKKASTMEGRKQVLMWTYTGTVAYSAPEIFDGDS
   .. .| .|.| ... |.| . . |||||| ||| .    ..   . .|| ||  ..|.. |            ..  | .  ||  | |||..    
EIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKD------------EKKYMFQKCGTPGYVAPEVLNNKE

------YDETVDMWSAGAVLYTMLAGYQPFEEEYVQDLIAKIKSADYTFPKNI-----SENAQDLIKKCLQIDPEKRIKPTEALAHPWI
      ||. .||||.|...|..| |..||. . ... . ..|   . |  ..     | ...||.|| |. ||.|||....|| ||| 
VLKHKQYDTKCDMWSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase 19367.AA CDPK 53-319 34 6.4e-70 213.69 In-house 1-271 (271) Show / Hide 
Range on Protein: 53-319
Range on HMM: 1-271/271
Sequence Identity: 34% (99 aa)

YREIEILGEGCVGLVKKVERL-SDGKIF-ASKMVKTKDEEEVV--LNVIREFKNLRELNHPNIVKVYELYVDETKGRIYTIME--LVEAKEMFDVISKLG
|   ..||.|  | |.||    ... .  | |... .   .     ....|.. |..| ||||.|.|| | ||    .| .||  ...  | ||.|   |
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKN--YYIVMETEYCTGGELFDYIIEKG

QYSESVAISIFKQILEAIDYLHENMVCHRDLKPNNIL--CNEDGT----CVKITDFNVSKFAHYDNAHKKASTMEGRKQVLMWTYTGTVAYSAPEIFDGD
...|  | .|..||| |. | |.| ..|||||| |||   ..|..     .|. |.  ||   .| .  |           | .  ||. | |||. .. 
HFTEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSK--KFDQN-QKI------EDKKMSQRCGTPYYIAPEVLQKK

SYDETVDMWSAGAVLYTMLAGYQPFEEEYVQDLIAKIKSADYTFP----KNISENAQDLIKKCLQIDPEKRIKPTEALAHPWI
 |.| .| ||.| .||..| || ||  .  |. ..|.|   |.|     ..||..|.|||.|.|. ||.||..  .||.|||.
-YNEKCDIWSCGVILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF
Kinase 19367.AA CAMK-Unique 53-319 23 6.1e-69 226.66 In-house 1-363 (363) Show / Hide 
Range on Protein: 53-319
Range on HMM: 1-363/363
Sequence Identity: 23% (88 aa)

YREIEILGEGCVGLVKKVERLSDGKIFASKMVKTKDEEEVVLNV-------------------IREFKNLRELNHPNIVKVYEL----YVDETK------
|. ..|.|.|  |.|...   . ||..| |||| .. .. .. .                    ||   .. ..||||.|.|.     ..|...      
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

-------GRIYTIMELVEAKEMFDVISK--------------------LGQYSE--SVAISIFKQILEAIDYLHENMVCHRDLKPNNILCNED-------
        ..|..||.......||.| |                     |..||  . ...|. ..|.|. |.|.. . |||||. ||. ..        
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

--------GTCVKITDFNVSKFAHYDNAHKKASTMEGRKQVLMWTYTGTVAYSAP--------------EIFDGDSYDETV----DMWSAGAVLYTMLAG
         . .|..||  ..  ||.. .. .         .| |. ||  | ||              |. ... ||. .    | || |...|.|| |
RDFPYDWSNWHIKLCDFGLCC--HYNHNKMCH---------MMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCG

YQPFEEEYVQ--------DLIAKIKSADY-TFPKN-------ISENAQDLIKKCLQIDPEKRIKPTEALAHPWI
. ||..|            ....|...|| .|..        ||..| |..|.|...|| .|..  |.| |.||
CPPFDCECEDRDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase 19367.AA CAMK-Tt 53-151 57 8.4e-67 228.24 In-house 1-137 (396) Show / Hide 
Range on Protein: 53-151
Range on HMM: 1-137/396
Sequence Identity: 57% (79 aa)

YREIEILGEGCVGLVKKVERLSDGKIFASKMVKTKDEEEVV--------------------------------------LNVIREFKNLRELNHPNIVKV
|.|.||||||||||||||.|.|||..||.|||.|.||||..                                      ..|||||||.|||||||||||
YEEQEILGEGCVGLVKKVKRISDGQVFACKMVRTRDEEEIMNHQSYNSEISSGQHKCQSTGELFEITKFTYFKSISQSKMQVIREFKNIRELNHPNIVKV

YELYVDETKGRIYTIMELVEAKEMFDVISKLGQYSES
||||.|||||||||||||.||||||.||.|||.|||.
YELYIDETKGRIYTIMELIEAKEMFEVIHKLGHYSEK
Kinase 19367.AA RSK 56-319 27 8.3e-60 205.0 In-house 1-278 (278) Show / Hide 
Range on Protein: 56-319
Range on HMM: 1-278/278
Sequence Identity: 27% (82 aa)

IEIL---GEGCVGLVKKVERLSDGKIFASKMVKT--KDEEEV-VLNVIREFKNLRELN-HPNIVKVYELYVDETKGRIYTIMELVEAKEMFDVISKLGQ-
.. |   | | | |..|...   |.|.| | .|    .  .. .  . .| . | . . ||.||. .. . .|.|  .| |||...  |.|. ..| .. 
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGK--LYLIMEYCRGGELFTHLQKEKHF

--YSESVAISIFKQILEAIDYLHENMVCHRDLKPNNILCNE-DGT--CVKITDFNVSKFAHYDNAHKKASTMEGRKQVLMWTYTGTVAYSAPEIFD---G
   ||. |  .. .|  |...||.  . |||||| ||| .. . .   .|.|||  .| .              ..  .. |. .|..| |||.     .
GCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQF------------RCDHNQWTMTFCYTIEYMAPEMLKRANQ

DS-YDETVDMWSAGAVLYTMLAGYQPFEE---EYVQDLIAKIKSAD--YTFP--KNISENAQDLIKKCLQIDPEKRIK-----PTEALAHPWI
.. .|. .| || |...|.||.|. ||     .  ......|....   |.|  ...|..|.|||.|.|. ||.||..       | ..|||.
QGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 19367.AA CAMKL 53-196 31 3.4e-41 129.13 In-house 1-173 (297) Show / Hide 
Range on Protein: 53-196
Range on HMM: 1-173/297
Sequence Identity: 31% (54 aa)

YREIEILGEGCVGLVKKVER-LSDGKIFASKMVK--TKDEEEVVLN------------VIREFKNLRELN---HPNIVKVYELYVDETK----GRIYTIM
|| .. ||.|  | ||  .  .  |.  | |...   . .......            . || . .. ||   ||||.| || . ....    . || .|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELVEAKE--MFDVISKLGQ----YSESVAISIFKQILEAIDYLHENMVCHRDLKPNNILCNEDGT-CVKITDF
|...  |  .|| | | |      .|. |  .|.||..|..|.|.....|||.|| |||  |.|   .||.||
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDF
Kinase 19367.AA CAMKL 227-319 39 1e-31 98.38 In-house 195-297 (297) Show / Hide 
Range on Protein: 227-319
Range on HMM: 195-297/297
Sequence Identity: 39% (41 aa)

GTVAYSAPEIFDG--DSYD-ETVDMWSAGAVLYTMLAGYQPFEEEYVQ-------DLIAKIKSADYTFP--KNISENAQDLIKKCLQIDPEKRIKPTEAL
|. .| ||||| |  ..||   ||.||.| .||.|. || ||... ..        |  ||..  | .|  . .|  ..|||.| || .||||..  . .
GSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIM

AHPWI
 ||| 
NHPWM
Kinase 19367.AA TyrKc 53-319 23 2.2e-13 -6.39 SMART 1-280 (280) Show / Hide 
Range on Protein: 53-319
Range on HMM: 1-280/280
Sequence Identity: 23% (70 aa)

YREIEILGEGCVGLVKKVERLSDGKIFASKMVKTKDEEEVVLNVIREFKNLREL--NHPNIVKVYELYVDETK-----GRIYTIMELVEAKEMFDVISKL
 . ...||||. | | | .        | ||.|       .   .|| . ...|  .|||||. |   ...       . .. .||...     | . | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

GQ-YSESVAISIFKQILEAIDYLHENMVCHRDLKPNNILCNEDGTCVKITDFNVSKFAHYD------NAHKKASTMEGRKQVLMWTYTGTVAYSAPEIFD
.   . .  .|.  || .  .|||.. . ||||   |.| .|.. .|||.||  |.. . |         ..... .|.| .|       .   ||| ..
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTML------PIRWMAPECIN

GDSYDETVDMWSAGAVLYTMLA-GYQPFEE-----EYVQDLIAKIKSADY-TFPKN--------ISENAQDLIKKCLQIDPEKRIKPTEALAHPWI
   . .  | || | ... ..  | || ..        |..|...|. ..   |.|         ..   ...|.| . |||.|   .|   |  .
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF