9133

Species: Tetrahymena
Alias: 9133, TTHERM_01309100, PreTt09133, 743, 319.m00015
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: CMGC
Family: RCK

Sequence

Name Sequence Type Origin Length Description Download
9133.AA Protein None 294 None Fasta, JSON
9133.kin_dom Protein Kinase Domain None 276 None Fasta, JSON
9133.NA RNA None 885 None Fasta, JSON

Protein domain

Protein domains of 9133.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 9133.AA RCK 15-290 35 5.6e-171 547.01 In-house 1-298 (298) Show / Hide
Range on Protein: 15-290
Range on HMM: 1-298/298
Sequence Identity: 35% (106 aa)

YIVLN----------------DQGKKLAMKKLKRGNTFADLEEAKNDIEVRHLNKLK-NEHVIEVLDVIYNSTDRTGFIILPYFQMNLFEFLEN----GK
|....                ..|...|.||.|  ..|...||..|..|...|.||. ....|....||.............|..|||......    .|
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKKMK--QKFYSWEECMNLREIKSLRKLNPHPNIIKLKEVIRDNDTYQLYFVFEYMDMNLYQMMKDFKERRK

KLQEFQR--RHIVKQLFQVLSFIHSQNIFHRDLHPENIMITDEQEYSSDKSLFNIKLIDFGSSKCRQDNQ-FTDYVGVRWYRAPELLLSCQKYDEKVDIF
.|.|.||  ..|..|..|.|...|....|||||.|||||.|..|.|..|.. ..||..|||......... .||||..|||||||.||.|..|....||.
YLPENQRSIKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREIRSKPPYTDYVSTRWYRAPECLLRCTYYNSPMDIW

ALGCIIYEIYHKKPLFPGTSELAQLNELCVILGSPTQEIWSKGVEQAEKKGLDLGKHKKSNLKVIFCDMPQDMVELCELCLTWNPEKRISAAEALNHKSI
|.|||.||.|...|||||.||..|....|...|.|....|..|...|..........|...||.......||..||.| .|.|.|.|||.|..||.|...
AVGCIMYELYMLRPLFPGSSEIDQIFKICKVMGTPNKKDWPDGYKLASQMNFNFPQCKGMPLKQLIPNCSQDCIELMEKMLQWDPQKRITAQQALQHPYF





Kinase 9133.AA CMGC 17-290 17 1.9e-85 280.64 In-house 33-513 (513) Show / Hide
Range on Protein: 17-290
Range on HMM: 33-513/513
Sequence Identity: 17% (86 aa)

VLNDQGKKLAMKKLKRGNTFADLEEAK-----------NDIEVRHLNKLK----------------NEH-VIEVLDVIYNST---------------DRT
.... ... |.||.|  | | . |.||              |.. | .|.                ... ..  .|..| .                .. 
HHHETNEIVAIKKIK--NPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNIVKLYDIFYHKNSDGNEYEDKHIISQHFNH

GFIILPYFQMNLFEFLENGK---------KLQEFQ------------RRHIV------KQLFQVLS--FIHSQN--IFHRDLHPENIMITDEQEY-----
 ...  | ...|.....| .         .| | .             ....      .|... |   ..||..  |.|||| ||||.|... |.     
LYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMM

--------SSDKSLFNIKLIDFGSSKCRQDN-----------------------QFTDYVGVRWYRAPELLLSC---------QKYDEKVDIFALGCIIY
           .. ...|..|||...   ..                       ..|.||  |||||||.||..         ..|....|. ..|||..
WKSEDWNPC--QKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFA

EIYHK--------KPLFPGTSE-----------LAQLNELCVILGSPT---------------QE-------------------------IWSKGVEQAE
|.| .        |||||| ||           . ||.. . .||.||               .|                         .||... .. 
EMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKLPWYNKFPKKWNWQTMTNHWSEFARNYI

KKGLDLGKHKKSNLKVIFCD-----------------------------------MPQDMVELCELCLTWNPEKRISAAEALNHKSI
........... ..| .| .                                   .... ..| . .|...|.|||.|..||.|  .
QSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF

Kinase 9133.AA MAK 18-290 31 2.1e-62 197.28 In-house 50-352 (352) Show / Hide
Range on Protein: 18-290
Range on HMM: 50-352/352
Sequence Identity: 31% (95 aa)

LNDQGKKLAMKKLKRGNTFADLEEAKNDIEVRHLNKLK-NEHVIEVLDVIYNSTDRTGFIILPYFQMNLFEFLENGKK--LQEFQRRHIVKQLFQVLSFI
..| | | | |. |.   | ..||. |  ||  | ||. . ...  . || .| . . .... | . ||.. .   ..  . |   | |. |  | | |.
IIDTGEKVAIKRMKK--KFYSWEECMNLREVKSLKKLNAHPNIVKLKEVIRDSENDHLYFVFEYMKENLYQMMKDRDRRHFPEPVIRNIMYQILQGLAFM

HSQNIFHRDLHPENIMITD-----EQEYSSDKSL---FNIKLIDFG-SSKCRQDNQFTDYVGVRWYRAPELLLSCQKYDEKVDIFALGCIIYEIYHKKPL
|  . ||||. |||||..      |.||           ||. |||     |  . .||||  ||||||| || . .|   .|. |.|||  |.|  .||
HKHGFFHRDMKPENIMCMGPTQYFEKEYMNQIGYQDNELIKIADFGLAREIRSKPPYTDYVSTRWYRAPEVLLRSTYYSSPIDMWAVGCIMAELYTFRPL

FPGTSELAQLNELCVILGSPTQEI----------------WSKGVEQAEKKGLDLGKHKK---SNLKVIFCDMPQ-DMVELCELCLTWNPEKRISAAEAL
|||.||  |.   | .||.|. .                 |  |   | . .. . .  .   ..|| .     | | .|| . .| |.|.||  |....
FPGSSEIDQIFKICQVLGTPKKDDDFVNTNHITAPPPGGFWPDGYQLAHMMNFRFPQCVPPSIMPLKHLIPNCSQSDAIELMKDMLQWDPNKRPTAQQCC

NHKSI
 ..  
KYPYF

S_TKc 9133.AA S_TKc 8-290 21 1.3e-55 191.99 SMART 1-231 (231) Show / Hide
Range on Protein: 8-290
Range on HMM: 1-231/231
Sequence Identity: 21% (65 aa)

LQAHDNL--------YIVLNDQ-GKKLAMKKLKRGNTFADLEEAKNDIEVRHLNKLKNEHVIEVLDVIYNSTDRTGFIILPYFQM---NLFEFLENGKK-
 . .. .        | . .   |.. |.|..|           .   |.. | | . ....  .||...      .... |      .||..... .. 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----LQEFQRRHIVKQLFQVLSFIHSQNIFHRDLHPENIMITDEQEYSSDKSLFNIKLIDFGSSKCRQDNQFTDYVGVRWYRAPELLLSCQKYDE-KVD
     . | . |....|... | ..||..| |||| ||||....           .||..|||...       | ..| .||.|||.|    .|.  |.|
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----------HIKICDFGLARQL-----TTFCGTPWYMAPEVL----GYGKCKCD

IFALGCIIYEIYHKKPLFPGTSELAQLNELCVILGSPTQEIWSKGVEQAEKKGLDLGKHKKSNLKVIFCDMPQDMVELCELCLTWNPEKRISAAEALN--
. ..|||.|| .  .|.||      |....  ..|                                    .... .. . ||...||||..| |||.  
WWSCGCILYEMLCGYPPFP------QMQMMFKKIG------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDE

-----HKSI
     |  .
WDIKCHPWF

Kinase 9133.AA Pkinase 22-290 23 1.4e-54 192.4 Pfam 24-293 (293) Show / Hide
Range on Protein: 22-290
Range on HMM: 24-293/293
Sequence Identity: 23% (67 aa)

GKKLAMKKLKRGNTFADLEEAKNDI---EVRHLNKLKNEHVIEVLDVIYNSTDRTGFIILPYFQM-----NLFEFLE--NGKKL--QEFQRRHIVKQLFQ
||. |.|..|.    .. .. ....   |.. ...|. ..... .|. ..  ..   ....| ..      ||....  .....  .| . .....|...
GKIVAVKIIKKR--HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILR

VLSFIHSQNIFHRDLHPENIMITDEQEYSSDKSLFNIKLIDFGSSKC--RQDNQFTDYVGVRWYRAPELLLSCQKYDEKVDIFALGCIIYEIYHKKPLFP
 | ..||..| |||| ||||.| .. . ..      .|..|||..|.     |..|...| .||.|||.....|.|. |||....|||.|| . ..|.||
GLEYCHSMGIIHRDLKPENILIDNNGHIDA-----CVKICDFGLAKQFDY-NNSMTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFP

GT----SELAQLNELCVILGSPTQEIWSKGVEQAEKKGLDLGKHKKSNLKVIFCDMPQDMVELCELCLTWNPEKRISAAEALNHKSI
|     . . |.  .| |.| |. . |..  .    . .   . .   ...    ..... .... ||...|.||..|...|.|. .
GHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 9133.AA CDK 47-290 26 1.4e-49 156.72 In-house 58-284 (284) Show / Hide
Range on Protein: 47-290
Range on HMM: 58-284/284
Sequence Identity: 26% (71 aa)

EVRHLNKLKNEHVIEVLDVIYNS-TD--------RTGFIILPYFQMNLFEFLENGKKLQEFQRRHIVKQLFQVLSFIHSQNIFHRDLHPENIMITDEQEY
|.  | .| ..... ..||.. . .|        .. ... .|  . | ....          ... .|| . |...||..| |||| | ||.|..  | 
EISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEYMDHDLKKYMD---------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGE-

SSDKSLFNIKLIDFGSSKCRQ--------DNQFTDYVGVRWYRAPELLLSCQKYD--EKVDIFALGCIIYEIYH---KKPLFPGTSELAQLNELCVILGS
   |    .|. ||| ..  .         . .|  |  .||||||||| ...|.    .|. ..|||..|..    .||||||.||. ||   . |.|.
--VK-CGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGT

PTQEIWSKGVEQAEKKGLDLGKHKKSNLKVIFCDMPQDMVELCELCLTWNPEKRISAAEALNHKSI
|| ..|   ..  .                          .| . .|. .|.||||| .||.|.  
PTEDNWPGVTKLPDY-------------------------DLLNKMLCYDPKKRISAEQALQHPYF

Kinase 9133.AA p38 101-290 31 1.1e-44 150.55 In-house 109-289 (289) Show / Hide
Range on Protein: 101-290
Range on HMM: 109-289/289
Sequence Identity: 31% (61 aa)

RHIVKQLFQVLSFIHSQNIFHRDLHPENIMITDEQEYSSDKSLFNIKLIDFGSSKCRQDNQFTDYVGVRWYRAPELLLSCQKYDEKVDIFALGCIIYEIY
. .| |.   | .||| .| |||| | || .... |          .  ||| .   .|.  |.||. ||||||| .|.  .|...|||  .|||. |. 
QFLVYQILRGLKYIHSAGIIHRDLKPSNIAVNEDCEL---------RILDFGLAR-HCDDEMTGYVATRWYRAPEIMLNWMHYTQTVDIWSVGCIMAELI

HKKPLFPGTSELAQLNELCVILGSPTQEIWSKGVEQAEKKGLD-LGKHKKSNLKVIFCDMPQDMVELCELCLTWNPEKRISAAEALNHKSI
  ..||||.  ..||...  ..|.|..|.|.|  ... .  .  . .... ... .|       ..| |  |   |.|||.|.||. |  .
TGRTLFPGDDHIDQLQRIMKVCGTPDEEFWQKIQSEEARNYIQSYPQMPRRDFHHVFMGANPQAIDLLEKMLELDPDKRITAEEAMQHPYF

Kinase 9133.AA ERK7 47-290 29 5.3e-44 148.2 In-house 48-292 (292) Show / Hide
Range on Protein: 47-290
Range on HMM: 48-292/292
Sequence Identity: 29% (76 aa)

EVRHLNKLK-NEHVIEVLDVIYNSTDRTGFIILPYFQMNLFEFLENGKKLQEFQRRHIVKQLFQVLSFIHSQNIFHRDLHPENIMITDEQEYSSDKSLFN
|.  |  ..  . .| ...||  . ||  ...  .    |      |. |..  .. |. ||.. . ..|| |. |||| | ||..          |   
EIMFLQEFHCHPNIIRLINVIRADNDRDIYLVFEFMETDLHAVIRKGNILKDIHKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILL---------DSECM

IKLIDFG-----SSKC---RQDNQFTDYVGVRWYRAPELLLSCQKYDEKVDIFALGCIIYEIYHKKPLFPGTSELAQLNELCVILGSPTQE-IWSKGVEQ
.|. |||     ...     |.   |.||  ||||||| ||. ..|   ||   .|||. |.  .||.||||| . |..    ... |||| | . | . 
VKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIGCILGEMLRGKPMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHY

AEKKGLDLGKHKKSNLKVIFCDMPQDMVELCELCLTWNPEKRISAAEALNHKSI
| .    ....|.  |. .. . ..| ..|    |  ||.||..| .||.|  .
AWNMLEQMNQQKRKTLDQMMPQCCDDAIDLLKRLLVFNPKKRLTAEQALQHPYV

Kinase 9133.AA CDC2 51-290 30 7e-43 129.28 In-house 54-301 (301) Show / Hide
Range on Protein: 51-290
Range on HMM: 54-301/301
Sequence Identity: 30% (79 aa)

LNKLK-NEHVIEVLDVIYNSTDRTGFIILPYFQMNLFEFLE----NGKKLQEFQRRHIVKQLFQVLSFIHSQNIFHRDLHPENIMITDEQEYSSDKSLFN
| .||  . ..   |||..   .  ...  |  |.| ....     .|....   . . .|. | ..| |.. |.|||| | || | .. .         
LKELKDHPNIVKLHDVIHQ---NKLYMVFEYLDMDLKKYMDMSIPKNKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGN---------

IKLIDFGSSK--CRQDNQFT--DYVGVRWYRAPELLLSCQKYDEKVDIFALGCIIYEI---YHKKPLFPGTSELAQLNELCVILGSPTQEIWSKGVEQAE
||. ||| ..  .   .. |    |  .||||||.|| |..|.  ||. ..|||..|.    .|||||.| ||  ||     |||.|. ..|  ||.|  
IKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTW-PGVTQLP

KKGLDLGKHKKSNLKVIFCD---------MPQDMVELCELCLTWNPEKRISAAEALNHKSI
    . .. |...|. |. .         .... ..| .  |  .|.||||| |||.|. .
DYKNTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQHPYF

Kinase 9133.AA Ciliate-E2 51-290 21 1.5e-42 143.92 In-house 86-365 (365) Show / Hide
Range on Protein: 51-290
Range on HMM: 86-365/365
Sequence Identity: 21% (71 aa)

LNKLKNEHVIEVLDVIYNSTDRTGFIILPYFQM-NLFEFLENG-----------KKLQEFQRRHIVKQLFQ---------------VLSFIHSQN-IFHR
| .|.. ..|.  .. .. .| . .... |.|  .||....|            |.. |.....| ||..|                | ..||.| |.||
LEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHR

DLHPENIMITDEQEYSSDKSLFNIKLIDFGSSK--------------CR-------------------QDNQFTDYVGVRWYRAPELLLSCQK-------
|. ||||..              ||.|||| ||              |                    |.|.|  ..|   | ||| | . .        
DIKPENILF--------------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQK

-YDEKVDIFALGCIIYEIYHKKPLFPGTSELAQLNELCVILGSPTQEIWSKGVEQAEKKGLDLGKHKKSNLKVIFC-------------------DMPQD
 ||.|.||..||.|.||   .|| |                                         .. . |. |                    . .|.
GYDYKCDIWSLGVILYEMLFGKPPF---------------------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQE

MVELCEL----CLTWNPEKRIS-AAEALNHKSI
.  |.      .|  .|||||. . ..|||. .
CKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase 9133.AA MAPK 111-287 30 3.3e-37 126.12 In-house 130-325 (328) Show / Hide
Range on Protein: 111-287
Range on HMM: 130-325/328
Sequence Identity: 30% (63 aa)

LSFIHSQNIFHRDLHPENIMITDEQEYSSDKSLFNIKLIDFGSSKCRQDNQF----------------TDYVGVRWYRAPELLLS--CQKYDEKVDIFAL
| .||| |. |||| |.|| .. . .          |. ||| . .  ....                |.||  |||||||..|.   ..|...||. ..
LKYIHSANVIHRDLKPSNILVNENCDL---------KICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAPEIMLNWIWMHYTKAVDMWSV

GCIIYEIYH-KKPLFPGTSELAQLNELCVILGSPTQEIWSKGV--EQAEKKGLDL---GKHKKSNLKVIFCD----MPQDMVELCELCLTWNPEKRISAA
|||  | .   ||||||.. . |.|    .||.|..| ...    | | .    |    |..| ... .|..       . . | |  |...|.|||...
GCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANPQAIDLLEKMLVFDPDKRITVE

EALNH
|||.|
EALQH

Kinase 9133.AA ERK 149-287 34 8.6e-33 115.27 In-house 158-304 (307) Show / Hide
Range on Protein: 149-287
Range on HMM: 158-304/307
Sequence Identity: 34% (50 aa)

IDFGSSKCR--QDNQFTDYVGVRWYRAPELLLSCQKYDEKVDIFALGCIIYEIYHKKPLFPGTSELAQLNELCVILGSP--TQEIWSKGVEQAEKKGLDL
.|......   ..|..|.||  |||||||..|| |||....|| . |||. | .  |||||| . . |.|.   |.|.|   ...  .. |.| |    |
FDASYQENHECNQNFMTEYVATRWYRAPEIMLSWQKYTKAMDIWSCGCIFAEMLGRKPLFPGKDYVHQINRIFQIIGTPHSEEDLQYICSENAWKYIKNL

GK--HKKSNLKVIFCDMP--QDMVELCELCLTWNPEKRISAAEALNH
..   .. ... || . .   ....| |  |...|.|||...|.| |
PNPVRPPKPWENIFPNANCNPQAIDLLEKMLVFDPDKRITVEECLEH

TyrKc 9133.AA TyrKc 12-290 17 2.2e-08 -87.07 SMART 1-280 (280) Show / Hide
Range on Protein: 12-290
Range on HMM: 1-280/280
Sequence Identity: 17% (57 aa)

DNLYIVL-------------NDQGKKLAMKKLKRGNTFADLEEAKNDI--EVRHLNKL--KNEHVIEVLDVIYNS-----TDRTGFIILPYFQM-NLFEF
  |  .|             .    . | |.|| .         . |.  | | . ||  ......  . |.  .      .   .|.. |    .| ..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

LENGKK-LQEFQRRHIVKQLFQVLSFIHSQNIFHRDLHPENIMITDEQEYSSDKSLFNIKLIDFGSSKCRQDN--------QFT------DY--VGVRWY
| . .. |.  .  ..  |  .  ...||.|. ||||   |.......          .|  ||| |.   |           .          . .||.
LRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM

RAPELLLSCQKYDEKVDIFALGCIIYEIYHK-KPLFPG-------TSELAQLNELCVILGSPTQ--EIWSKGVEQAEKKGLDLGKHKKSNLKVIFCDMPQ
 ||| .    |. .| |... |  ..||.   ..  ||        .|. .. .    .  |    .  |                        |  .|.
-APECI-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYP-MS------------------------FVCCPD

DMVELCELCLTWNPEKRISAAEALNHKSI
.| .. . |   .||.| . .|   |. .
EMYQIMKQCWHEDPEDRPTFSEI--HECF

Kinase 9133.AA ERK 113-132 55 3e-05 15.71 In-house 123-142 (307) Show / Hide
Range on Protein: 113-132
Range on HMM: 123-142/307
Sequence Identity: 55% (11 aa)

FIHSQNIFHRDLHPENIMIT
.|||.|..|||| | || ..
YIHSANVIHRDLKPSNILVN