Gene 10482 (Tetrahymena)

10482

Species: Tetrahymena
Alias: n.10482, 1145, 76.m00184, TTHERM_00569540, 10482, PreTt10482
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-A8

Sequence

Name Sequence Type Origin Length Description Download
10482.AA Protein None 849 None Fasta, JSON
10482.kin_dom Protein Kinase Domain None 89 None Fasta, JSON
10482.NA RNA None 2550 None Fasta, JSON

Protein domain

Protein domains of 10482.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 10482.AA Ciliate-A8 59-199 45 1e-55 190.28 In-house 1-151 (151) Show / Hide 
Range on Protein: 59-199
Range on HMM: 1-151/151
Sequence Identity: 45% (68 aa)

YIQQQIIYKQDLYQVAIVCSKDFQELFACHSFQSIYDQKDVDQNEFEKIIKALQYLQNENNILSIIEKIEHTQQGLTTIITEFVDC--------NLTQII
|. | .. | |   | .  | ..|...|   ..    |. .   ||||.|.|.|...||..||.|||.|....||...|.|||.||        ||..|.
YKYQKVLEKGDFSYVVQAYSINHQCQVAIKIIKYMNQQNKINDKEFEKCIQAMQKIKNEKYILQIIECIQDKEQGFIAIVTEFCDCFDFYKKKENLASIL

E--LNRFNFEQIIALTYQLLNCLNLHQEKGIIYHDIKHDSIFFSKSKNQFF
|  ||.|.||||.|||||||.||...||||||..|||...|..|.||||| 
ENNLNKFTFEQIVALTYQLLKCLLVFQEKGIIHCDIKPQNILYSWSKNQFI
Kinase 10482.AA Ciliate-E1 65-248 14 8.4e-10 28.53 In-house 1-202 (202) Show / Hide 
Range on Protein: 65-248
Range on HMM: 1-202/202
Sequence Identity: 14% (30 aa)

IYKQDLYQVAIVCSKDFQ-ELFACHSFQSIYDQKDVDQNEFEKIIK-ALQYLQNENNILSIIEKIEHTQQGLTTIITEFVDCNLTQIIE-----------
| . .  .| .  ..  . .  |   .. .. ........  | ..  .. ...| .|. ||. |.. |  ...||.|...|.|.. ..           
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQC

---LNRFNFEQIIALTYQLLNCLNLHQEKGIIYHDIKHDSIFFSKSKNQFFIA-----NYQQLKTTKNTFFKKISDFLKINSINQSTEVLSQYEPEPTSD
    | |.|.|......||.  |.  . ..||. ||| . | .... ... ..       ......... .|   . .. .   .. |. . ..... . 
QQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQ-GNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQ-EHNKNQKINY

NLFSI
..  .
KSDIY
Kinase 10482.AA CMGC 108-185 18 1.1e-07 20.35 In-house 72-211 (513) Show / Hide 
Range on Protein: 108-185
Range on HMM: 72-211/513
Sequence Identity: 18% (26 aa)

IKALQYLQ----------------NENNILSIIEKIEHTQ---------------QGLTTIITEFVDCNLTQIIELNRF--------NF-----------
|| |..|.                ..|||..... . | .                    ...|..|..| |.|. |.|        ..           
IKILKHLNKNHDPNWQRRDDPDNKHHNNIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRR

--EQIIALT------YQLLNCLN---LHQEKG-IIYHDIK
  ..|  ..      ||.|..|.   .|. .| ||  |.|
PPHNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLK
Kinase 10482.AA S_TKc 72-319 15 3.6e-07 -71.85 SMART 14-231 (231) Show / Hide 
Range on Protein: 72-319
Range on HMM: 14-231/231
Sequence Identity: 15% (43 aa)

QVAIVCSKDFQELFACHSFQSIYDQKDVDQNEFEKIIKALQYLQNENNILSIIEKIEHTQQGLTTIITEFVDC---NLTQIIELNR-------FNFEQII
.|  .  |. ....|.              . ... |. |.   .  ||  ... ...   .   ...|..|    .| ..|. ..       |.  .. 
KVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HAR

ALTYQLLNCLN-LHQEKGIIYHDIKHDSIFFSKSKNQFFIANYQQLKTTKNTFFKKISDF---LKINSINQST----------EVLSQYEPEP-TSDNLF
 ..||... |. .|.  |||. |.| . |....                      ||.||    ..     .|          |||      .  .|   
FYMYQICCALEYCHSH-GIIHRDLKPENILLDE--------------------HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCD-WW

SIGIILTEVYIQRSLNNIELQNLKNQTLLNVLPFLQQSSNIEFINKILSKMLESNKDIRLMLNILIQ-----NLNTFF
|.|.|| | .  . .   ..| . .. .             |... ...|.|. . . |.    . |     ..  .|
SCGCILYEMLCGYPPFP-QMQMMFKKIG-----------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 10482.AA Ciliate-E2-Unclassified 93-201 18 1.4e-05 15.31 In-house 37-189 (352) Show / Hide 
Range on Protein: 93-201
Range on HMM: 37-189/352
Sequence Identity: 18% (29 aa)

IYDQKDV--DQNEFEKIIKALQYLQ------NENNILS----------IIEKIEH-TQQGLTTIITEFV-DCNLTQIIEL------------------NR
||.|| .   . |.  ..|... ..      . | |.           |. .... ...    |..|.. . .| |.|.                   ..
IYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKY-NKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKI

FNFEQII-----ALTYQLLNCL-NLHQEKGIIYHDIKHDSIFFSKSKN--QFFIA
|  .|..      ...|.|..|  ||....||. ||| . |.|.....  .  |.
FTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKII
Kinase 10482.AA PAKB 146-189 43 0.000115 13.12 In-house 83-126 (252) Show / Hide 
Range on Protein: 146-189
Range on HMM: 83-126/252
Sequence Identity: 43% (19 aa)

LTQIIELNRFNFEQIIALTYQLLNCLNLHQEKGIIYHDIKHDSI
|| |.   | | ||| .   | |  |     .|.|  ||| |||
LTDIVTHTRMNEEQIATVCRQVLQALAYLHAQGVIHRDIKSDSI
Kinase 10482.AA MOK 108-189 28 0.000293 8.69 In-house 48-131 (283) Show / Hide 
Range on Protein: 108-189
Range on HMM: 48-131/283
Sequence Identity: 28% (24 aa)

IKALQYLQNENNILSIIEKIEHTQQGLTTIITEFVDCNLTQIIELNRFNF--EQIIALTYQLLNCLNLHQEKGIIYHDIKHDSI
|.|.. |.   ||| . | .   . |  ..| | .| |.  .|   |.    ..|    |||.  |.     ||   |.| . |
IQAMRRLNPHPNILMLHEVVFDRKTGNLALICELMDMNIYELIRGRRHYLPQKKIMHYMYQLCKSLDHMHRNGIFHRDVKPENI
LRR_RI 10482.AA LRR_RI 440-467 35 0.001897 17.75 SMART 1-28 (28) Show / Hide 
Range on Protein: 440-467
Range on HMM: 1-28/28
Sequence Identity: 35% (10 aa)

NVACLYLNLADNKLGPEGAKSIGMSLEA
|   . |.|..||||.||.. .  .|..
NCSLRELWLSNNKLGDEGCRQLCEGLKH
LRR_RI 10482.AA LRR_RI 470-497 32 0.064727 6.93 SMART 1-28 (28) Show / Hide 
Range on Protein: 470-497
Range on HMM: 1-28/28
Sequence Identity: 32% (9 aa)

NITSLTINLQNNDLRDEGINKFGLSLEK
| . ....|.||.| |||.  .  .|. 
NCSLRELWLSNNKLGDEGCRQLCEGLKH
Band_7 10482.AA Band_7 567-765 17 1.3e-18 64.35 Pfam 1-187 (187) Show / Hide 
Range on Protein: 567-765
Range on HMM: 1-187/187
Sequence Identity: 17% (37 aa)

DTVEVVHYGLL-----CNSISKACSQKSVYGAGRHWVWP---TYYFIYFPSNLLTIEFSDSANANPPLKTRTAEGLSLELFLSFEFQLIKEEIPQLYSMN
 .|.  ..|..        ...      |...|.||.||   .  .....  . |.||..       ....|..|. . . ... ... .. .|..| . 
YIVPPGEVGVVWFTRMFGKVQR-----RVLEPGWHWKWPWWFIQRIYRVDTRQQTYEFTF-------QTVPTKDGQ-VNVDVTVQYRINPDDPPKFYQNY

NLEYERTFIRIARDTIVQIA---STFEANEYWTK-RNNVTQAMKNELTIELKKAHAKCV-FFQLLRIDLPDSYEMSIVNTQIEMQNKRTKQFEQEATRIL
  .|..   ....... ...   ......|  .. |. ..|..|..|. .|.|    ..  .|. .||.|.    .. .  . |. | | | |.|.    
--DYQEQIQPVVQSALREVIRVAGRMTLDEIYNNKREEIAQEIKERLQEQLDKWGIEIEVDVQITDIDPPP----EYQEA-F-MEEKMTAQQEAER----

KEIEVLRSETEK
.. |. |.|.|.
AQAEIERAEQEA