Gene 22331 (Tetrahymena)

22331

Species: Tetrahymena
Alias: TTHERM_00219030, PreTt22331, 18.m00357, 512, 22331, 3701.m00116
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-C4

Sequence

Name Sequence Type Origin Length Description Download
22331.AA Protein None 1587 None Fasta, JSON
22331.kin_dom Protein Kinase Domain None 337 None Fasta, JSON
22331.NA RNA None 4764 None Fasta, JSON

Protein domain

Protein domains of 22331.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 22331.AA Ciliate-C4 982-1320 51 1.4e-237 769.07 In-house 1-361 (361) Show / Hide 
Range on Protein: 982-1320
Range on HMM: 1-361/361
Sequence Identity: 51% (187 aa)

LIKKKLLGRGGFALVWLGEDKQTKENYAVKQILSSN---AHQTHIKEIWFGSFFFKNGVAKEKYQMYRGVNNLSKMMN------YEIKQVDTWIYYELCG
.||.|.||.|||.||||...|.|....|.|||...|   .||.|.|||||.||...||..||.||||.|..||..||.      |...|.||||.|||||
YIKRKCLGKGGFSLVWLCKQKKTQQQFACKQICNQNNQDSHQRHMKEIWFYSFYMRNGQVKEYYQMYQGFKNLPQMMYNEILINYMKDQKDTWIIYELCG

ESLGSSLYELKGEGYRGEERVYRVHYKKLYQSIKRDLRQ--FKKLIFELAHALWLLSDQRIVHSDLKTENILVKTK-DNGGFTEIEQVKLIDYGSSFTFG
.||..||||.|||.|...||||....||||.....|...  .||.|....||||.|.....||.|.|.||||||.| |.||...|.||||||.||.|.|.
KSLRKSLYEIKGEDYCQNERVYKINFKKLYYHLFQDKNNNLCKKFIQHICHALWHLHQNKWVHCDIKPENILVKYKSDFGGSNNIQQVKLIDFGSCFQFN

NLKHFS-MATPEYMAPEILNFILYQN------QLRHIPYLLEYLKNYQKTYVIDIWSLGCVMMEIISGIPLWMSLKTIVKHKG-QELIRHGLFAAKGRVF
|.||.. |||||||.||.||||....      |..|......||.||.....|||||.||||||||.|||.|||.|..|.||. ...|.||.|..|...|
NKKHIQSMATPEYMPPEMLNFIIQEQNEDEQLQQNHQHDMFQYLQNYECPWSIDIWSMGCVMMEIITGIPHWMSYKCRVHHKQVKNFIKHGIFCHKQQCF

ENIIEKQIEVVKSIDTYIDEHNYSG--VVVDQDLRYLVKKMLVLDPSKRISPKEVCQFLHK
||||.||....|.||.|..||||..  .|.||.|..|.||||...|..|||||..||..  
ENIIQKQKKFCKQIDQYMKEHNYQFCCQVIDQQLKDLIKKMLKFNPRERISPKQCCQHPWI
Kinase 22331.AA S_TKc 982-1322 16 1.9e-26 95.1 SMART 1-231 (231) Show / Hide 
Range on Protein: 982-1322
Range on HMM: 1-231/231
Sequence Identity: 16% (59 aa)

LIKKKLLGRGGFALVWLGEDKQTKENYAVKQILSSNAHQTHIKEIWFGSFFFKNGVAKEKYQMYRGVNNLS-------KMMNYEIKQVDTWIYYELCGES
  . ...|.|.|. |... .| |.. .|.|.|                             ...| .. |.       |.  .     . ..  |.|. .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------------------------EHIRREIQILKKHHPNIVKLYDVFQD-DHLYMVMEYCDGD

LGSSLYELKGEGYRGEERVYRVHYKKLYQSIKRDLRQFKKLIFELAHALWLLSDQRIVHSDLKTENILVKTKDNGGFTEIEQVKLIDYGSSFTFGNLKHF
||. .  .|  |..|  ...             .  . .... ... ||  . ...|.| ||| ||||. .          ..|..| |..  .    . 
LGDLFDYIKKRGRHGLRFPF-------------PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----------HIKICDFGLARQL----TT

SMATPEYMAPEILNFILYQNQLRHIPYLLEYLKNYQKTY-VIDIWSLGCVMMEIISGIPLWMSLKTIVKHKGQELIRHGLFAAKGRVFENIIEKQIEVVK
   ||.|||||.|                      . ..  .|.||.||.. | ..| |..           |..... .                    
FCGTPWYMAPEVL----------------------GYGKCKCDWWSCGCILYEMLCGYPPFP--------QMQMMFKKIG--------------------

SIDTYIDEHNYSGVVVDQDLRYLVKKMLVLDPSKRISPKEVCQ-----FLHKSV
                ..... ...|.|. ||.||..  |. |      .|  .
----------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 22331.AA Pkinase 1128-1318 19 1.6e-23 84.25 Pfam 126-293 (293) Show / Hide 
Range on Protein: 1128-1318
Range on HMM: 126-293/293
Sequence Identity: 19% (40 aa)

DQRIVHSDLKTENILVK-TKDNGGFTEIEQVKLIDYGSS----FTFGNLKHFSMATPEYMAPEILNFILYQNQLRHIPYLLEYLKNYQKTYVIDIWSLGC
...|.| ||| ||||.. . ...       ||..| |..       .   .    ||.|||||...                  ..   .. .|.||.||
SMGIIHRDLKPENILIDNNGHIDA-----CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR------------------GGQYYGPKVDMWSCGC

VMMEIISGIPLWMSL---------KTIVKHKGQELIRHGLFAAKGRVFENIIEKQIEVVKSIDTYIDEHNYSGVVVDQDLRYLVKKMLVLDPSKRISPKE
.. | ..| |.. .          . |.. .| .| ..      .. |. .   . .         . |    . ...... ..|..| .||.||.....
ILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H---------F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQ

VCQF--L
..|   .
ILQHPWF
Kinase 22331.AA Ciliate-E2 1130-1316 22 4.6e-22 72.52 In-house 181-361 (365) Show / Hide 
Range on Protein: 1130-1316
Range on HMM: 181-361/365
Sequence Identity: 22% (54 aa)

RIVHSDLKTENILVKTKDNGGFTEIEQVKLIDYGS--------------------------SFTFGNLKHFSMA------------TPEYMAPEILNFIL
.|.| |.| ||||.             .|.|| |                           | |.|...                 ||.||||||||   
NIIHRDIKPENILF-------------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMD----QIIQQNMFNTICGTPGYMAPEILNGKK

YQNQLRHIPYLLEYLKNYQKTYVIDIWSLGCVMMEIISGIPLWMSLKTIVKHKGQELIRHGLFAAKGRVFENIIEKQIEVV------KSIDTYIDEHNY-
|.||           |  . .| .||||||... | ..| | .                          ...|....|.        .  .  | . .. 
YDNQ----------QKQKGYDYKCDIWSLGVILYEMLFGKPPF--------------------------QQQIKQCKIDFPCPEWQKD-TQ-CI-QCKWK

SGVVVDQDLRYLVKK----MLVLDPSKRIS-PKEVCQ
|   ..|.   | ||    ||. ||.|||. .... .
SWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILN
Kinase 22331.AA Ciliate-E2-Unclassified 1098-1230 22 2.2e-12 39.27 In-house 126-266 (352) Show / Hide 
Range on Protein: 1098-1230
Range on HMM: 126-266/352
Sequence Identity: 22% (36 aa)

YKKLYQSIKRDLRQFK-----KLIFELAHAL-WLLSDQRIVHSDLKTENILVKTKDNGGFTEIEQVKLIDYGSSFTFGNL-----------------KHF
.....|. . . .| |     ... ..  .|  | . . |.| |.| ||||.. . .       ..|.||.|.|   ..                  .  
FHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK-----NYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMW

SMA-TPEYM----APEILNFILYQNQLRHIPYLLEYLKNYQKTYVIDIWSLGCVMMEIISG
... ||.||    |||.|    | ..                 | .||||||... |.. |
TFCGTPNYMPQYTAPEVLQGQNYDHSKA---------------YKCDIWSLGVILYEMLFG
Kinase 22331.AA CAMK 1128-1232 23 3.2e-12 34.95 In-house 197-332 (425) Show / Hide 
Range on Protein: 1128-1232
Range on HMM: 197-332/425
Sequence Identity: 23% (34 aa)

DQRIVHSDLKTENILVKTK-------------DNGGFTEIEQVKLIDYGSS--FTFGNLKHF------------------------SMATPEYMA-PEIL
.. ||| ||| ||||. ..             |     .  ..|.|| | .  |. |.  ..                        .  |||||| ||.|
SHNIVHRDLKPENILLDDNNDDSDPVEHDEIFD----WNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVL

NFILYQNQLRHIPYLLEYLKNYQKTYVIDIWSLGCVMMEIISGIP
|    .|      .   . ..   .. .|.||.|...    .| |
NGKGHCNMQ----N-ATDEEKPYYGPKCDMWSCGVILYIMLCGYP
Kinase 22331.AA STE 1111-1188 22 1.7e-11 37.0 In-house 152-235 (359) Show / Hide 
Range on Protein: 1111-1188
Range on HMM: 152-235/359
Sequence Identity: 22% (22 aa)

QFKKLIFELAHA-LWLLSDQRIVHSDLKTENILVKTKDNGGFTEIEQVKLIDYGSSFTFGN------------------LKHFSMA-TPEYMAPEILN
| .. .... .. | .| ...|.| |.|  |||.             |||.| | .  . .                   |  ... || .||||...
QIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-------------VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQ
Kinase 22331.AA CMGC 1101-1234 19 3.1e-11 32.23 In-house 141-343 (513) Show / Hide 
Range on Protein: 1101-1234
Range on HMM: 141-343/513
Sequence Identity: 19% (42 aa)

LYQSIKRDL------------------------RQFKKLI------FELAHA--LWLLSDQR--IVHSDLKTENILVKTKD-------------NGGFTE
||| ||.                          .. |...      . .  .  |  .  ..  |.| ||| ||||.  .              |    .
LYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPC-QK

IEQVKLIDYGSSFTFGN----------------------LKHFS--MATPEYMAPEILN-FILYQNQLRHIPYLLEYLKNYQKTYVIDIWSLGCVMMEII
  ..|..| |..  ...                      .....   .|  | |||||     | |.        .| ..|  |. ||.||.||.. |..
NGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLGWKHYTNH--------NYSMHY--TTPIDMWSVGCIFAEMY

SG--------IPLW
 |         ||.
TGYQSLIFRGKPLF
Kinase 22331.AA CAMKL 1128-1192 32 7.7e-10 27.43 In-house 145-212 (297) Show / Hide 
Range on Protein: 1128-1192
Range on HMM: 145-212/297
Sequence Identity: 32% (24 aa)

DQRIVHSDLKTENILVKTKDNGGFTEIEQVKLIDYGSS--FT-F----GNLKHFSMATPEYMAPEILNF--ILY
...||| |.| ||||.  ..|       ..|.|| | |  ..      |.. . .  .|.||||||..     |
SHGIVHRDIKPENILLDENGNN------NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPY
Kinase 22331.AA CDPK 1131-1188 40 5.4e-09 23.95 In-house 124-187 (271) Show / Hide 
Range on Protein: 1131-1188
Range on HMM: 124-187/271
Sequence Identity: 40% (26 aa)

IVHSDLKTENILVKTKDNGGFTEIEQVKLIDYGSSFTFGN------LKHFSMA-TPEYMAPEILN
||| ||| |||| ..|...    | ..|.|| | |  |.        |.  .. || |.|||.|.
IVHRDLKPENILFDSKKDDSWV-IYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQ
Kinase 22331.AA Ciliate-E2b 1126-1188 34 1.8e-08 22.06 In-house 118-178 (272) Show / Hide 
Range on Protein: 1126-1188
Range on HMM: 118-178/272
Sequence Identity: 34% (24 aa)

LSDQRIVHSDLKTENILVKTKDNGGFTEIEQVKLIDYGSSFTFGNLKH-----FSMA-TPEYMAPEILN
|  | |.. |.| |||.|  |         ..|||| | . ..   .      |..  ||.||||||..
LHNQNIIYRDIKPENIMVDHK--------GYMKLIDMGTAKHMYKKNEQMTRTFTIIGTPHYMAPEIIQ
Kinase 22331.AA CAMK 987-1013 30 1.5e-07 19.66 In-house 267-305 (425) Show / Hide 
Range on Protein: 987-1013
Range on HMM: 267-305/425
Sequence Identity: 30% (12 aa)

LLGRGGFALVWLGEDKQTK------------ENYAVKQI
 ||||.|. | |...|.|.            . .|.| |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKII
Kinase 22331.AA Ciliate-E2b 982-1023 37 3e-07 18.28 In-house 1-43 (272) Show / Hide 
Range on Protein: 982-1023
Range on HMM: 1-43/272
Sequence Identity: 37% (16 aa)

LIKKKLLGRGGFALVWLGED-KQTKENYAVKQILSSNAHQTHI
.|  |.||.| |  |.|.   |.||. || |.| ..   |. .
MIYIKKLGFGQFGSVYLVWNTKNTKQYYAMKCISKNQIIQQNM
Kinase 22331.AA Ciliate-B1 1128-1189 35 5.1e-07 20.73 In-house 136-202 (290) Show / Hide 
Range on Protein: 1128-1189
Range on HMM: 136-202/290
Sequence Identity: 35% (24 aa)

DQRIVHSDLKTENILVKTKD----NGGFTEIEQVKLIDYG-SSFTFG-NLKHFSMATPEYMAPEILNF
.. |.| |||.||||.  |        .... ..|  |.| |....  ... ..  |. |||||||||
KHKICHRDLKPENILIHKKNVPIYYNKQQNHYIFKITDFGISKMQQEYMMQSCV-GTINYMAPEILNF
Kinase 22331.AA CMGC 1290-1316 44 5.3e-07 18.07 In-house 483-509 (513) Show / Hide 
Range on Protein: 1290-1316
Range on HMM: 483-509/513
Sequence Identity: 44% (12 aa)

DQDLRYLVKKMLVLDPSKRISPKEVCQ
|.... |.||||..||.|||.... .|
DPQAIDLLKKMLQYDPDKRITAEQALQ
Kinase 22331.AA CMGC 982-1026 16 6.2e-07 17.82 In-house 232-303 (513) Show / Hide 
Range on Protein: 982-1026
Range on HMM: 232-303/513
Sequence Identity: 16% (12 aa)

LIKKKLLGRGGFALVWLGED--------------KQTKENYAVKQILSSNAHQTH--------------IKEI
  . | .|.| .. |. . |              ..|.| .|.| | .   ....              . ||
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREI
Kinase 22331.AA TyrKc 982-1318 14 7e-07 -111.34 SMART 1-280 (280) Show / Hide 
Range on Protein: 982-1318
Range on HMM: 1-280/280
Sequence Identity: 14% (55 aa)

LIKKKLLGRGGFALVWLGEDKQTKENYAVKQILSSNAHQTHIKEIWFGSFFFKNGVAKEKYQMYRGVNNLSKM--MN--------YEIKQ-------VDT
. ..| ||.| |  |..|. |   .. ||| . ..                        .  ..|  . ..|    .        . ..|          
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----------------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPL

WIYYELC-GESLGSSLYELKGEGYRGEERVYRVHYKKLYQSIKRDLRQFKKLIFELAHALWLLSDQRIVHSDLKTENILVKTKDNGGFTEIEQVKLIDYG
.|  |.. . .| . | . ...                       .... .  .  |     |......| || . |.||. .         .||  | |
MIVMEYMPHGDLKDYLRKHRPK---------------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--------TVKISDFG

SSFTFGNL-------KHFSMAT---PE------YMAPEILNFILYQNQLRHIPYLLEYLKNYQKTYVIDIWSLGCVMMEIIS-GIPLW-------MSLKT
 |   ..        .  ....            |||| .                 | |   |.   |.|| | .| || . | . .       || . 
LSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI----------------NYGKFTTKS---DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQE

IVKHKGQELIRHGLFA----AKGRVFENIIEKQIEVVKSIDTYIDEHNYSGVVVDQDLRYLVKKMLVLDPSKRISPKEVCQFL
....  |   .         .                            . |   ...  . |.    ||..| . .|.....
VIEYVKQGYRMPQPPNDYPMS----------------------------F-VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 22331.AA Ciliate-E2 982-1013 25 2e-06 18.19 In-house 125-156 (365) Show / Hide 
Range on Protein: 982-1013
Range on HMM: 125-156/365
Sequence Identity: 25% (8 aa)

LIKKKLLGRGGFALVWLGEDKQTKENYAVKQI
 .. |..|.|.|. |............| |.|
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKII
Kinase 22331.AA CAMKL 982-1013 36 2e-06 16.15 In-house 177-209 (297) Show / Hide 
Range on Protein: 982-1013
Range on HMM: 177-209/297
Sequence Identity: 36% (12 aa)

LIKKKLLGRGGFALVWLGED-KQTKENYAVKQI
 .  | ||.|.|. | |... . |.| .|.| |
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKII
Kinase 22331.AA CAMK 1289-1318 31 2e-06 15.68 In-house 394-425 (425) Show / Hide 
Range on Protein: 1289-1318
Range on HMM: 394-425/425
Sequence Identity: 31% (10 aa)

VDQDLRYLVKKMLVLDPSKRISPKEVCQ--FL
|.|. . |..|||. ||.||.. ... .  ..
VSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 22331.AA CAMKL 1289-1316 35 1.3e-05 13.75 In-house 267-293 (297) Show / Hide 
Range on Protein: 1289-1316
Range on HMM: 267-293/297
Sequence Identity: 35% (10 aa)

VDQDLRYLVKKMLVLDPSKRISPKEVCQ
|. |.| | .|||. .|.||.. ... .
VS-DCRDLIRKMLQVNPEKRPTIHQIMN
Kinase 22331.AA Ciliate-E2-Unclassified 983-1017 31 2e-05 14.84 In-house 193-227 (352) Show / Hide 
Range on Protein: 983-1017
Range on HMM: 193-227/352
Sequence Identity: 31% (11 aa)

IKKKLLGRGGFALVWLGEDKQTKENYAVKQILSSN
.. | .|.|||. |.. ..|..|. || |.. ...
KIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQ
Kinase 22331.AA CDPK 982-1013 35 2.8e-05 12.39 In-house 1-34 (271) Show / Hide 
Range on Protein: 982-1013
Range on HMM: 1-34/271
Sequence Identity: 35% (12 aa)

LIKKKLLGRGGFALVWLGEDK-QTKENY-AVKQI
 ..|| ||.|.|  | .. .| .|..   |.|.|
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKII
Kinase 22331.AA Pkinase 982-1013 31 2.9e-05 19.69 Pfam 1-32 (293) Show / Hide 
Range on Protein: 982-1013
Range on HMM: 1-32/293
Sequence Identity: 31% (10 aa)

LIKKKLLGRGGFALVWLGEDKQTKENYAVKQI
. ... .|.|.|. |... .| | . .|||.|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKII
Kinase 22331.AA Ciliate-B1 982-1016 23 3.2e-05 14.36 In-house 1-38 (290) Show / Hide 
Range on Protein: 982-1016
Range on HMM: 1-38/290
Sequence Identity: 23% (9 aa)

LIKKKLLGRGGFALVWLGE---DKQTKENYAVKQILSS
  .....| |..  | .|.   ..|... .|||.| ..
YQQNNVIGQGAISQVFYGQFCQNQQCQQEVAVKKITKQ
Kinase 22331.AA STE 982-1026 17 4.5e-05 14.01 In-house 26-104 (359) Show / Hide 
Range on Protein: 982-1026
Range on HMM: 26-104/359
Sequence Identity: 17% (14 aa)

LIKKKLLGRGGFALVWLGEDK------QTKEN---------YAVKQILSSNA-------------------HQTHIKEI
. . . .|.|.|  | .. ..      .|.|.         .|.||.  .|                    .|  .|||
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEI
Kinase 22331.AA Ciliate-B1 1206-1228 54 0.000145 12.03 In-house 200-223 (290) Show / Hide 
Range on Protein: 1206-1228
Range on HMM: 200-223/290
Sequence Identity: 54% (13 aa)

LK-NYQKTYVIDIWSLGCVMMEII
|. | | .. .||||.|| | |||
LNFNQQYDKKVDIWSFGCIMYEII
Kinase 22331.AA Ciliate-E2-Unclassified 1289-1316 21 0.001012 8.81 In-house 317-348 (352) Show / Hide 
Range on Protein: 1289-1316
Range on HMM: 317-348/352
Sequence Identity: 21% (7 aa)

VDQDLRYLVK----KMLVLDPSKRISPKEVCQ
...    ...    |||. .|.|||.......
WSPEAKDFINDLLQKMLKKNPNKRITFEQILN
Kinase 22331.AA CDPK 1296-1310 60 0.009856 4.45 In-house 247-261 (271) Show / Hide 
Range on Protein: 1296-1310
Range on HMM: 247-261/271
Sequence Identity: 60% (9 aa)

LVKKMLVLDPSKRIS
|..|||. || ||.|
LIRKMLCYDPKKRMS
Kinase 22331.AA STE 1216-1230 60 0.012464 5.26 In-house 250-264 (359) Show / Hide 
Range on Protein: 1216-1230
Range on HMM: 250-264/359
Sequence Identity: 60% (9 aa)

DIWSLGCVMMEIISG
|||||||...| . |
DIWSLGCTIIEMATG