Gene 29096 (Tetrahymena)

29096

Species: Tetrahymena
Alias: 469.m00006, 29096, TTHERM_01564120, 60, PreTt29096
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-C7

Sequence

Name Sequence Type Origin Length Description Download
29096.AA Protein None 387 None Fasta, JSON
29096.kin_dom Protein Kinase Domain None 175 None Fasta, JSON
29096.NA RNA None 1164 None Fasta, JSON

Protein domain

Protein domains of 29096.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 29096.AA Ciliate-C7 13-175 80 5.4e-123 395.97 In-house 1-164 (164) Show / Hide 
Range on Protein: 13-175
Range on HMM: 1-164/164
Sequence Identity: 80% (132 aa)

FRFLGQGAQGLVLLAKNSKTKMRYAIKGVQVRDSEGNIDEDLSNTVRQEVEILKKCGGSPYVVSLLDQFEGKQFSYLVLTECQ-GTLTQILERNQNKRLN
|||||||.||||||||..||.||||||||||||..||||.|. | |.||..|||.| .|||||.||.||||.||.||||.||| |||.||.|||||||||
FRFLGQGQQGLVLLAKDQKTNMRYAIKGVQVRDKQGNIDQDINNQVQQEINILKQCKDSPYVVCLLHQFEGQQFIYLVLNECQGGTLNQIIERNQNKRLN

EISAIKYANDIAQGLYYIHSKNCLVNDLKMDNILIDYHGNAVVSDFGMADNLTYKSGYAINQYM
||||||||.||||||||||||||.|||||||||||||.|||||.|||.|||||.||.|.|||||
EISAIKYAKDIAQGLYYIHSKNCVVNDLKMDNILIDYNGNAVVCDFGLADNLTQKSKYQINQYM
Pkinase 29096.AA Pkinase 10-160 29 8.8e-27 95.77 Pfam 1-159 (293) Show / Hide 
Range on Protein: 10-160
Range on HMM: 1-159/293
Sequence Identity: 29% (47 aa)

YSDFRFLGQGAQGLVLLAKNSKTKMRYAIKGVQVRDSEGNIDEDLSNTVRQEVEILKKCGGSPYVVSLLDQFEGKQFSYLVLTECQG-----TLTQILER
|   | .|.|. | | .... .|  ..|.| . .|. . . |. . ..  .|..|.|.. ..|..| |.| || |.  |.|.  |.|      |  ....
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL--SEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST

NQNKRL--NEISAIKYANDIAQGLYYIHSKNCLVNDLKMDNILIDYHGNA----VVSDFGMA
 .....   |  ...|.  |..||.|.||....  ||| .||||| .|.      ..||| |
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLA
Kinase 29096.AA AGC 13-160 24 3.4e-25 60.72 In-house 1-202 (395) Show / Hide 
Range on Protein: 13-160
Range on HMM: 1-202/395
Sequence Identity: 24% (51 aa)

FRFL---GQGAQGLVLLAKNS------KTKMRYAIKGVQVRD---------SEGNIDE-------DLSNTVRQEVEILKKCGG---------SPYVVS-L
|.||   |.|. | | |..         |.  ||.| .. ..          | .. |       .    |..| .||.|| .         .|..|. |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGY----VWEERNILEKCNHTHNHPIKSHHPFIVKIL

LDQFEGKQF--SYLVLTECQ----------G-TLTQILERN-QNKRLNEISAIKYAND-------IAQGLYYIHS-KNCLVND-LKMDNILIDYHGNAVV
   |. |.    |.|.  ..          |  | ..|    ...|..|  |  ||         |. .| |.|| ..    | || .|||.| .|.   
HYSFQDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKL

SDFGMA
.|||..
TDFGLC
Kinase 29096.AA CAMKL 10-160 25 1.9e-23 71.57 In-house 1-176 (297) Show / Hide 
Range on Protein: 10-160
Range on HMM: 1-176/297
Sequence Identity: 25% (45 aa)

YSDFRFLGQGAQGLVLLAKN-SKTKMRYAIKGVQ--VRDSEGNID--------EDLSNTVRQEVEILKKCG--GSPYVVSLLDQFEGKQF------SYLV
|   . ||.|. | | ||.. . |. ..||| .       . ...        |.    .|.|..|.|.    . | ...|.. .| ...       |||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV

LTECQGT---LTQILERNQNKR--LNEISAIKYANDIAQGLYYIHSKNCLVNDLKMDNILIDYHG--NAVVSDFGMA
.  |.|    | . .... ..|  . |  | .|   |  ...|.||..    |.| .|||.|..|  |. ..|||..
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFS
Kinase 29096.AA Ciliate-E1 16-201 18 1.9e-23 73.45 In-house 1-202 (202) Show / Hide 
Range on Protein: 16-201
Range on HMM: 1-202/202
Sequence Identity: 18% (38 aa)

LGQGAQGLVLLAKNSKTK-MRYAIKGVQVRDSEGNIDEDLSNTVRQEVEILKKCGGSPYVVSLLDQFEGKQ--FSYLVLTECQGTLTQILE---------
.|.| ...|. ||. ...   .|.| ..... .  ....  .  ... .|.|   .  |.. ..|... .|  ........|. .|.. |.         
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQ--DEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQ

--RNQNKRLNEISAIKYANDIAQGLYYIHSKNCLVNDLKMDNILIDYHGNAVVSDFGMADNLTYKSGYAINQYMGNFLYQAPECYD-----PADSDIGKV
  ..... ...   .. . .. .|| ..|..| .  |.|..||||.  || | .||| ...| ... . ...      |. ||.|      . .... . 
QCQQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQEHNKNQKINY

YHDEY
  | |
KSDIY
Kinase 29096.AA CAMK 15-184 18 4.4e-23 70.61 In-house 1-290 (425) Show / Hide 
Range on Protein: 15-184
Range on HMM: 1-290/425
Sequence Identity: 18% (54 aa)

FLGQGAQGLVLLAKNSKTK------------MRYAIKGVQVRDSEGNI----------------------DEDLSNTVRQEVEILKKCGG------SPYV
 ||.|. | | |... .|.             ..||| .  .   ..                       ..     ||.|.||.||. |       | .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VSLLDQFEG-------------------KQFSYLVL---TECQGT------LTQILERNQN------------KRLNEISAIKYANDIAQGLYYIHSKNC
..|.. .|                    ... |.|.     |.|       .  | |. ..            .|..|  | .|   |.... |.||.| 
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

LVNDLKMDNILIDYH-----------------GNAVVSDFGMADNLTYKS----------------------GYAINQYMGNFLYQA-PE
   ||| .|||.|..                 .|  ..|||.|  .. ..                      |   . . |   | | ||
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPE
Kinase 29096.AA Ciliate-E2-Unclassified 10-187 21 2.2e-22 74.48 In-house 1-239 (352) Show / Hide 
Range on Protein: 10-187
Range on HMM: 1-239/352
Sequence Identity: 21% (53 aa)

YSDFRFLGQGAQGLVLLAKNSKTKMRY------AIKGVQVRDSEGNIDEDLSNTVRQEVEILK---------------KCGGSPYVVSLLDQFEGKQFSY
|   . .|||..| | .....|.|  |        . .. . .  | | ...|   .|....|               .   .|..| ....|. ||  |
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMN-EMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIY

LVLTEC-QGTLTQILE---------------RNQNKRLNEISAI-----KYANDIAQGLYYIHSKN-CLVNDLKMDNILIDYHG---NAVVSDFGMADNL
.|.  | .|.| |...               ..|.|.. |  |.     .|.  | ||| |.|.|| ..  |.| .|||.|  |   .  ..||| . ..
IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKY

TYKSGYA--------------INQYMGNFLYQ----APECYD
 . ...               ... .|.  |.    |||...
QQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQ
S_TKc 29096.AA S_TKc 10-273 22 2.1e-21 78.38 SMART 1-231 (231) Show / Hide 
Range on Protein: 10-273
Range on HMM: 1-231/231
Sequence Identity: 22% (65 aa)

YSDFRFLGQGAQGLVLLAKNSKTKMRYAIKGVQVRDSEGNIDEDLSNTVRQEVEILKKCGGSPYVVSLLDQFEGKQFSYLVLTECQG---TLTQILERNQ
|   | .|.|| | | .... ||. ..||| .              ...|.|..||||  . |..| |.| |.  .. |.|.  | |   .| .......
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRG

NKR----LNEISAIKYANDIAQGLYYIHSKNCLVNDLKMDNILIDYHGNAVVSDFGMADNLTYKSGYAINQYMGNFLYQAPECYDPADSDIGKVYHDEYL
 ..    ..|  | .|.  |...| |.||.. .  ||| .|||.|   .  ..|||.|  |        . . |   | |||                | 
RHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL-------------GYG

K-----------LGVNVRLQPSNRGINISLALNKHKQLNYDGEFTNFVYHKQLKYIIEGLTNFVPKNRMPIKEALI-----ILKGII
|           |   .  .|  .  .. . ..| .              ...| .|... .. |..|. . |||       .   .
KCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 29096.AA Ciliate-E2 10-184 18 4.8e-21 68.96 In-house 1-257 (365) Show / Hide 
Range on Protein: 10-184
Range on HMM: 1-257/365
Sequence Identity: 18% (49 aa)

YSDFRFLGQGAQGLVLLAKNSKTKMRYAIK-------------GVQ--------VRDSEGNIDEDLSNTVR---------QEVEILKKCGGSPYVVSLLD
|   . .|||..| | ..|. |.. ..|||             .|.        .. .. .. .   .  |         .| .||..   .|... . .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLN-HPNIIKMYE

QFE--GKQFSYLVLTECQG-TLTQILERN----------QNKRLNEISAIKYANDIAQ---------------GLYYIHSKN-CLVNDLKMDNILIDYHG
 |.   ..  |||.  ||| .| .... |          . |...|  ....   |.|               .| |.|||| ..  |.| .|||.    
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

NAVVSDFGMADNLTYK---------SGYAINQY----------------------MGNFLYQAPE
   ..|||.. ... .         ..  ..                         |.  |.|||
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPE
Kinase 29096.AA ULK 10-160 25 1.4e-19 65.12 In-house 1-189 (329) Show / Hide 
Range on Protein: 10-160
Range on HMM: 1-189/329
Sequence Identity: 25% (48 aa)

YSDFRFLGQGAQGLVLLAKNSKTK----MRYAIKGVQ---VRDSE----GNIDEDLSNTVRQEVEILKKCG---GSPY----VVSLLDQFEGKQF--SYL
|.  . ||.|. | |  ..| |||      .|.| ..    . ..    |   . . . ...|..|.||     ....    .| |.| || ...   |.
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEG---QYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYI

VLTECQG-TLTQILERNQN--------KRLNEISAIKYANDIAQGLYYIHSKNCLVNDLKMDNILIDYHGNAV------------VSDFGMA
..  |.| .| |....|..        |||.|  ||..  .|..|. ..|..|.   |.| .||||. .                ..||| |
IMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFA
Kinase 29096.AA ULK 10-160 26 2.8e-18 61.52 In-house 1-185 (324) Show / Hide 
Range on Protein: 10-160
Range on HMM: 1-185/324
Sequence Identity: 26% (49 aa)

YSDFRFLGQGAQG-LVLLAKNSKT---KMRYAIKGVQ---VRD--SE--GNIDEDLSNTVRQEVEILKKCG--GSPY--VVSLLDQFEGK--QFSYLVLT
|.  . ||.|. |  |  ..| ||   .  .|.| ..    ..  .|  |   . . .  ..|..|.||     .|.  .| |.| || .   . |... 
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEG---QYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIME

ECQG-TLTQILERNQN-------KRLNEISAIKYANDIAQGLYYIHSKNCLVNDLKMDNILIDYHGNAV------------VSDFGMA
 |.| .| |....|..       |||.|  ||..  .|..|. ..|..|.   |.| .||||  .                ..||| |
YCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFA
Kinase 29096.AA STE 10-158 20 1.1e-17 59.07 In-house 1-192 (359) Show / Hide 
Range on Protein: 10-158
Range on HMM: 1-192/359
Sequence Identity: 20% (41 aa)

YSDFRFLGQGAQGLVLLAKNSK---------------TKMRYAIKGVQVRDSE-----------GNIDEDLSNTVRQEVEILKKCGG-SPYVVSLLDQFE
. . ...|.|| | | .|.| |               |. ..||| . .....            |....  . . .|..|.|||   .|..|  .. ..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

GK-------QFSYLVLTECQ-GTLTQILE------RNQN------KRLNEISAIKYANDIAQG-LYYIHSKNCLVNDLKMDNILIDYHGNAVVSDFG
 .       .  ....  .  |.|..|..      ...|      .|..|   .... .| .| |||.||..    |.| .|||.     .  .|||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFG
Kinase 29096.AA TyrKc 10-269 17 1.8e-07 -101.75 SMART 1-280 (280) Show / Hide 
Range on Protein: 10-269
Range on HMM: 1-280/280
Sequence Identity: 17% (54 aa)

YSDFRFLGQGAQGLVLLAKNSKTKMRYAIKGVQVRDSEGNIDEDLSNTVRQEVEILKKCG-GSPYVVSLLDQFEGKQ------FSYLVLTE--CQGTLTQ
 .  . || || | | ... .   .  |.| ..                ..| .|..| |   | .| |.     ..        .....|  . | | .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

ILERNQNKRLNEISAIKYANDIAQGLYYIHSKNCLVNDLKMDNILIDYHGNAVVSDFGMADNLTYK------SGYAINQY--MGNFL----YQAPECYDP
 | ....| |.    .... .||.|  |.|||||   ||   |.|..  . . .||||.. ... .      . |   .    |...      |||| . 
YLRKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINY

A----DSDI-------------GKVYHDE-----------YLKLGVNVRLQPSNRGINISLALNKHKQLNYDGEFTNFVYHKQLKYIIEGLTNFVPKNRM
      ||.             |.  . .           . ..    |. .   .  .|              |     .. .  |..   .. |..| 
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS--------------F--VCCPDEMYQIMKQCWHEDPEDRP

PIKEALIIL
  .|   ..
TFSEIHECF