Gene 28529 (Tetrahymena)

28529

Species: Tetrahymena
Alias: 992, 3829.m01348, 28529, 13.m00488, PreTt28529, TTHERM_00161390
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-A5

Sequence

Name Sequence Type Origin Length Description Download
28529.AA Protein None 1340 None Fasta, JSON
28529.kin_dom Protein Kinase Domain None 90 None Fasta, JSON
28529.NA RNA None 4023 None Fasta, JSON

Protein domain

Protein domains of 28529.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 28529.AA Ciliate-A5 246-351 27 1.6e-14 46.86 In-house 172-275 (275) Show / Hide 
Range on Protein: 246-351
Range on HMM: 172-275/275
Sequence Identity: 27% (31 aa)

YLSPQLFTRLKHR---YVQGFNANKPEEQRSNEVSQVFSLGLVAIEMATLKSV-RKIYDFDYYSLNKGKLLDKLGLISN-LYSPQLAYIIAKMITFSEKD
||||...  ..||    .|  . |..        | ||.||... ||.|. ..   .||..  .  . .|...|       || |.  .|..|  | | .
YLSPMQWYQMMHRDEQNIQRPEHNWYK-------SDVFCLGMICLEMCTMRDCTQFYYDYETFQIQNNQLIKQLIQMKEKKYSEQFINFIKQMLQFEENK

RFTFNQTLDYI
| .| |   | 
RPDFHQIYQYL
Kinase 28529.AA Ciliate-A5 36-157 21 8.5e-14 44.28 In-house 1-122 (275) Show / Hide 
Range on Protein: 36-157
Range on HMM: 1-122/275
Sequence Identity: 21% (27 aa)

LYGESQLMQYKESLHHPYLVLKSRLLASKSEYEEFIKEPQKRKNMRSPYLIPLLNIYQIKQQDYCSKYFKVYMLYAYCEKTLFDAMIEMNELQ--QTFKE
 ||.  ..  | ..   |.. |.  . ...  . |... ..|..  .|... |... . |. . ||  .||  .| |   .|.  |..   .|    ..|
FYGCMKIW--KNQHQQEYYICKQKQIQDEDRQKHFQQYFEQRMQLQHPNIVKLIDFHTHKKEEFCSQFYKVNCYYEYHDNNLEQEMQMRKQCQKDIFYNE

QEIIQMIENVLQGLIFLKQNGISH
||.  ..  ... . .|.||.| |
QELWYIMDCLISVCMYLQQNNICH
Kinase 28529.AA Ciliate-E4 55-181 22 6e-08 23.08 In-house 28-150 (150) Show / Hide 
Range on Protein: 55-181
Range on HMM: 28-150/150
Sequence Identity: 22% (29 aa)

VLKSRLLASKSEYEEFIKEPQKRKNMRSPYLIPLLNIYQIKQQDYCSKYFKVYMLYAYCEKTLFDAMIEMNELQQTFKEQEIIQMIENVLQGLIFLKQNG
|.| |   .  . ..      .|.    . .| .. . . |    ||   ..|... |  | |       .  .| | |.|| |.      .. .| | .
VMKIRKFQNETKARQQQQQFRRRQDLNHENIIMVYEYFHKKEDQFCSSIYRLYWFMEYLQKDLQQHIKQHKQQGQHFDESEIWQIAFCCINAMYYLQQVN

ISHDTIKASTIAIANNSDSQNVSGIAD
| |  .|.| | . ..   . |  |||
ITHGDLKPSNIFFDQY---FMVK-IAD
S_TKc 28529.AA S_TKc 26-351 13 7.1e-07 -76.06 SMART 1-231 (231) Show / Hide 
Range on Protein: 26-351
Range on HMM: 1-231/231
Sequence Identity: 13% (46 aa)

THLVREMNTDLYGESQLMQYKESLHHPYLVLKSRLLASKSEYEEFIKEPQKRKNMRSPYLIPLLNIYQIKQQDYCSKYFKVYMLYAYCEK---TLFDAMI
 ...|.     .|.  . . |.   . .  .|          | ...| |  |. . |... |. ..|           ..||   ||.    .||| . 
YEILRKIGKGAFGKVYKCRHKK--TGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD---------DHLYMVMEYCDGDLGDLFDYIK

EMNE--LQQTFKEQEIIQMIENVLQGLIFLKQNGISHDTIKASTIAIANNSDSQNVS----GIADYLCNSYKKVNTSNSANKQANINQDLENTNFLSLAN
...   |.. | | ..  ..  ....| .. ..|| |  .| . | . .     ..     |.|  |                                 
KRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL---------------------------------

VKYQIADSKFMHNGKDAYTSAILGENQDF-----YLSPQLFTRLKHRYVQGFNANKPEEQRSNEVSQ----VFSLGLVAIEMATLKSVRKIYDFDYYSLN
                            |     |..| ..                        .     . |.| . .||.. .             .
--------------------------TTFCGTPWYMAPEVL----------------------GYGKCKCDWWSCGCILYEMLCGYPPFP---------Q

KGKLLDKLGLISNLYSPQLAYIIAKMITFSEKDRFTFNQTLD---------YI
  ....|.|      ||..  .| |. ..  ..| |  . |          ..
MQMMFKKIG------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 28529.AA Ciliate-E1 90-189 25 1.7e-05 14.36 In-house 54-165 (202) Show / Hide 
Range on Protein: 90-189
Range on HMM: 54-165/202
Sequence Identity: 25% (28 aa)

NIYQIKQQDYCS-KYFKVY-MLYAYCEKTLFDAMI---------EMNELQQTFKEQEIIQMIENVLQGLIFLKQNGISHDTIKASTIAIANNSDSQNV-S
..|.|. .||   .. ...  .  .|...|.| .          .... |. |..|...|.| . ..||| |.|..| |  || . | | |..  ..   
ECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQCQQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDF

GIADYLCNSYKK
||.. |.|. ..
GISKFLKNNQNQ
Kinase 28529.AA SLK 27-172 19 6.1e-05 12.47 In-house 2-135 (259) Show / Hide 
Range on Protein: 27-172
Range on HMM: 2-135/259
Sequence Identity: 19% (29 aa)

HLVREMNTDLYGESQLMQYKESLHHPYLVLKSRLLASKSEYEEFIKEPQKRKNMRSPYLIPLLNIYQIKQQDYCSKYFKVYMLYAYCEKTLFDAMIEMNE
... |.    .|  .  | ||     .   |.  . .. | |... | .   ..  |... |.. | . .        |..|.  .|.    |..  | |
EIIGELGDGAFGKVYKAQHKEQKV--FAAAKMIEIKDEEELEDYMVEIDILSECKHPNIVKLYEAYYYDN--------KLWMMIEFCDGGAVDNI--MVE

LQQTFKEQEIIQMIENVLQGLIFLKQNGISHDTIKASTIAIANNSD
|... .|. |  . . ....| .| .| . |  .||  | .. . |
LEHPLTEDQIQYVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGD
Kinase 28529.AA Ciliate-B2 114-172 30 0.000166 6.4 In-house 81-142 (197) Show / Hide 
Range on Protein: 114-172
Range on HMM: 81-142/197
Sequence Identity: 30% (19 aa)

EKTLFDAMIEMN--ELQQ-TFKEQEIIQMIENVLQGLIFLKQNGISHDTIKASTIAIANNSD
||  ..   |..  ..||  |..| ..||| . . ||| .. . | |  || . | . .| .
EKCECSLKQELQKIQKQQKCFNNQKLYQMIFQLIDGLIQFRMYNILHLDIKPQNILFMQNGN
Kinase 28529.AA STE 112-155 17 0.000274 11.19 In-house 118-173 (359) Show / Hide 
Range on Protein: 112-155
Range on HMM: 118-173/359
Sequence Identity: 17% (10 aa)

YCE-KTLFDAMIEMNELQQTFK----------EQEIIQMIENVLQG-LIFLKQNGI
|..  .| | . .  . .....          |..|. ..  .|.| | .| ...|
YMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHI
Kinase 28529.AA STE 279-293 60 0.062295 2.76 In-house 251-265 (359) Show / Hide 
Range on Protein: 279-293
Range on HMM: 251-265/359
Sequence Identity: 60% (9 aa)

VFSLGLVAIEMATLK
. |||...||||| |
IWSLGCTIIEMATGK