Gene 24905 (Tetrahymena)
24905
Group:
Other
Family:
Ciliate-E1
Sequence
Protein domains of 24905.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 24905.AA | Ciliate-E1 | 40-123 | 30 | 1e-18 | 57.84 | In-house | 1-88 (202) | Show / Hide |
Range on Protein: 40-123 Range on HMM: 1-88/202 Sequence Identity: 30% (27 aa) IGHGCYTETFTAFQANNNQIVVIKVLIDMN---NKEYIDAFTKEKN-LLKTIKNNKYSLQIIDDLE-DKNLDFAAIVVEHCDSDFRQSQ ||.|.. | |.| |||...|....| .. |..... .|| . ..| .|...|..|||| .. |.|. ...|. ..|.|.... | IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQ |
|||||||||
| Kinase | 24905.AA | Ciliate-A8 | 34-119 | 35 | 3.4e-18 | 59.91 | In-house | 1-89 (151) | Show / Hide |
Range on Protein: 34-119 Range on HMM: 1-89/151 Sequence Identity: 35% (32 aa) YVILQKIGHGCYTETFTAFQANNNQIVVIKVLIDMNNKEYIDA--FTKEKNLLKTIKNNKYSLQIIDDLEDKNLDFAAIVVEHCDS-DF |.. ... | . . | . | ...|.||....||. | . | |... . ||| || ||||....||.. | ||| | ||. || YKYQKVLEKGDFSYVVQAYSINHQCQVAIKIIKYMNQQNKINDKEFEKCIQAMQKIKNEKYILQIIECIQDKEQGFIAIVTEFCDCFDF |
|||||||||
| Kinase | 24905.AA | CK2 | 34-65 | 41 | 2.2e-09 | 23.41 | In-house | 1-34 (288) | Show / Hide |
Range on Protein: 34-65 Range on HMM: 1-34/288 Sequence Identity: 41% (14 aa) YVILQKIGHGCYTETFTAFQANNNQIV--VIKVL | . .||| | | | | ... .||. . |||.| YEVIRKIGRGKYSEVFEGINIKNNEKCKIVIKIL |
|||||||||
| Kinase | 24905.AA | S_TKc | 34-239 | 15 | 2.6e-09 | -40.48 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 34-239
Range on HMM: 1-231/231
Sequence Identity: 15% (43 aa)
YVILQKIGHGCYTETFTAFQANNNQIVVIKVLIDMNNKEYIDAFTKEKNLLKTIKNNKYSLQIIDDLEDKNLDFAAIVVEHCDS------DFRQSQ----
| ||.|||.| . . . . . ..|| ||.. . . .| ..|| . .. ...| .| |. .| |.|| |. ...
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG
--------------------------------------------------ISSQNQKQSSGNDQYFYGDQCYRSPEVLNQQKPPYTFKKADVFSIGQLLV
.. | | | |..|||| .|...|.|. |.| .|
LRFPFPEHARFYMYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQL--------TTFCGTPWYMAPEVL-----GYGKCKCDWWSCGCILY
EVFLQRKLSVNESMNLKQKSLFEAIPDLKNYQNNTFINDILINMANPNQDQRLEPFELLQ-----NMQKFT
| . .. .. .|. | ... .. .. . . ..|. |.|| .. .
EMLC-GYPPFP-----QMQMMFKKIG------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
|
|||||||||
| Kinase | 24905.AA | ULK | 34-121 | 17 | 3.8e-08 | 24.62 | In-house | 1-109 (329) | Show / Hide |
Range on Protein: 34-121 Range on HMM: 1-109/329 Sequence Identity: 17% (20 aa) YVILQKIGHGCYTETFTAFQA----NN---NQIVVIKVLI----DMNNKEY-----IDAFTKEKNLLKTIK---NNKY----SLQIIDDLEDKNLDFAAI |.. ...|.| . . ... .. |..|..|.. ...|.|. .. ...| ..|..| ..|. . .| .|..| . | YCLNHCLGKGSFG---KVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYI VVEHCDS-DFRQ ..| |. |..| IMEYCNGGDLEQ |
|||||||||
| Kinase | 24905.AA | PASK | 34-63 | 30 | 9.3e-08 | 19.94 | In-house | 1-30 (260) | Show / Hide |
Range on Protein: 34-63 Range on HMM: 1-30/260 Sequence Identity: 30% (9 aa) YVILQKIGHGCYTETFTAFQANNNQIVVIK |...|..| | | .... .. |||.| YTSIQQMGEGAYGYVWMCIHNECRYIVVVK |
|||||||||
| Kinase | 24905.AA | ULK | 34-116 | 19 | 3.3e-07 | 21.69 | In-house | 1-100 (324) | Show / Hide |
Range on Protein: 34-116 Range on HMM: 1-100/324 Sequence Identity: 19% (20 aa) YVILQKIGHGCYTETFTAFQA----NN--NQIVVIKVLI--DMNNKEY-------IDAFTKEKNLLKTIK--NNKY--SLQIIDDLEDKNLDFAAIVVEH |.. ...|.| . .. ... .| ||.| .|. ||.|.. .. . .| ...|..| .... . .| .|..| .. |..| YCLNHCLGKGSFG--VKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEY CD |. CN |
|||||||||
| Kinase | 24905.AA | KHS | 34-88 | 23 | 1.6e-05 | 14.43 | In-house | 1-54 (258) | Show / Hide |
Range on Protein: 34-88 Range on HMM: 1-54/258 Sequence Identity: 23% (13 aa) YVILQKIGHGCYTETFTAFQANNNQIVVIKVLIDMNNKEYIDAFTKEKNLLKTIK | .||..| | | . . | . . .... .|| | |. . . .| ..|. . YELLQRVGSGTYGDVYKARDIQSDELAAVKV-IKMEPGDDFAVIQQEIMMMKDCR |
|||||||||
| Kinase | 24905.AA | MAPK | 34-63 | 30 | 2.1e-05 | 14.37 | In-house | 1-36 (328) | Show / Hide |
Range on Protein: 34-63 Range on HMM: 1-36/328 Sequence Identity: 30% (11 aa) YVILQKIGHGCYTETFTAFQAN------NNQIVVIK |.||..||.| | . |.. ....|.|| YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIK |
|||||||||
| Kinase | 24905.AA | CMGC | 34-65 | 26 | 2.7e-05 | 12.35 | In-house | 1-46 (513) | Show / Hide |
Range on Protein: 34-65 Range on HMM: 1-46/513 Sequence Identity: 26% (12 aa) YVILQKIGHGCYTETFTAFQ--------------ANNNQIVVIKVL | |..|||.| | . . .. ..|.|| || . YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKI |
|||||||||
| Kinase | 24905.AA | Ciliate-C8 | 115-172 | 28 | 3.4e-05 | 14.93 | In-house | 165-238 (238) | Show / Hide |
Range on Protein: 115-172 Range on HMM: 165-238/238 Sequence Identity: 28% (21 aa) CD----SDFRQSQISSQNQK-----QSSGNDQY----FYGDQCYRSPEVLNQ----QKPPYTFKKADVFSIGQLL || || .. ..|. . | ||| |.| | |||... | ...| |..| | .| CDFKKQCDFGFASQLPKNKSHYHSKKFKGTDQYIEMYFCGNWGYFAPEVEKKQSRIQSDIFSKK-SDSYSVGLVL |
|||||||||
| Kinase | 24905.AA | ULK | 147-169 | 36 | 0.000385 | 10.66 | In-house | 215-239 (324) | Show / Hide |
Range on Protein: 147-169 Range on HMM: 215-239/324 Sequence Identity: 36% (9 aa) SPEVLNQQ--KPPYTFKKADVFSIG .|..|..| . ||. .|.|..|.| APQILQGQGEQKPYYDYKCDIWSLG |
|||||||||
| Kinase | 24905.AA | ULK | 147-169 | 36 | 0.000396 | 10.41 | In-house | 219-243 (329) | Show / Hide |
Range on Protein: 147-169 Range on HMM: 219-243/329 Sequence Identity: 36% (9 aa) SPEVLNQQ--KPPYTFKKADVFSIG .|..|..| . ||. .|.|..|.| APQILQGQGEQKPYYDYKCDIWSLG |
|||||||||
| Kinase | 24905.AA | Ciliate-E1 | 125-166 | 26 | 0.004033 | 6.56 | In-house | 162-202 (202) | Show / Hide |
Range on Protein: 125-166 Range on HMM: 162-202/202 Sequence Identity: 26% (11 aa) SSQNQKQSSGNDQYFYGDQCYRSPEVLNQQKPPYTFKKADVF ....|.| .| .|.| ..| .||. . .|. .| |.. NQNQQCQYKGYTHYYYPPEQYNCPEQ-EHNKNQKINYKSDIY |
|||||||||
| LRR_RI | 24905.AA | LRR_RI | 323-350 | 25 | 0.365912 | 1.62 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 323-350 Range on HMM: 1-28/28 Sequence Identity: 25% (7 aa) DCQEVELKYRSNQINEEGAKAIGISLEE | || ..| . .||.... .|.. NCSLRELWLSNNKLGDEGCRQLCEGLKH |
|||||||||
| LRR_RI | 24905.AA | LRR_RI | 353-380 | 39 | 0.003965 | 15.49 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 353-380 Range on HMM: 1-28/28 Sequence Identity: 39% (11 aa) NISLLNLILKNNNFSAEGVKILGTHLEQ | ||. | | ||.. .||.. | |.. NCSLRELWLSNNKLGDEGCRQLCEGLKH |
|||||||||
| LRR_RI | 24905.AA | LRR_RI | 383-410 | 32 | 0.000301 | 21.36 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 383-410 Range on HMM: 1-28/28 Sequence Identity: 32% (9 aa) NISFLDLNLGNNNIGERGVKAIGTSLEQ | | . |.|.||..|. |.... .|.. NCSLRELWLSNNKLGDEGCRQLCEGLKH |
|||||||||