Gene 21877 (Tetrahymena)

21877

Species: Tetrahymena
Alias: PreTt21877, 21877, 996, TTHERM_00726110, 117.m00129
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-Unique

Sequence

Name Sequence Type Origin Length Description Download
21877.AA Protein None 659 None Fasta, JSON
21877.kin_dom Protein Kinase Domain None 24 None Fasta, JSON
21877.NA RNA None 1980 None Fasta, JSON

Protein domain

Protein domains of 21877.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 21877.AA Ciliate-E2-Unclassified 74-157 23 2.4e-10 32.11 In-house 149-260 (352) Show / Hide 
Range on Protein: 74-157
Range on HMM: 149-260/352
Sequence Identity: 23% (26 aa)

LNQVCQGLQYLHRKE-IVHGDLNLKNIEINPANN--EIQLMNMSLPSKFQL-----------------KLIKNPYQMQEFE----SPEQKQEENIS----
. |..|||.|||.|  |.| |. . || ..  ..  .| .   .. .| |                  ....   .  ..     .||  |..| .    
FAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA

YSSDLYSLGVLA
|..| .||||..
YKCDIWSLGVIL
Kinase 21877.AA Ciliate-E2 76-156 16 3.1e-09 27.85 In-house 168-285 (365) Show / Hide 
Range on Protein: 76-156
Range on HMM: 168-285/365
Sequence Identity: 16% (21 aa)

QVCQGLQYLHRKE-IVHGDLNLKNIEINPANNEIQLMNMSLPSKFQLK-----------LIKNPYQ-----------------------MQEFESPEQKQ
.....|.||| |  |.| |. . || .      | .  . |  |.. .           ....  .                       . .. .||  .
CIILALEYLHSKNNIIHRDIKPENILF------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILN

EEN---------ISYSSDLYSLGVL
 ..          .|..|..||||.
GKKYDNQQKQKGYDYKCDIWSLGVI
Kinase 21877.AA TBCK 76-112 35 1.4e-08 26.77 In-house 88-127 (346) Show / Hide 
Range on Protein: 76-112
Range on HMM: 88-127/346
Sequence Identity: 35% (14 aa)

QVCQGLQYLHRKEIVHGDLNLKNIEINPANN---EIQLMN
|. .||.|.|.. |||. | ..|| ... .|    . | |
QILCGLSYMHKHHIVHRFLHPHNIYLDDNGNQKLHVKLAN
Kinase 21877.AA Ciliate-C3 76-113 42 2e-08 26.57 In-house 104-140 (140) Show / Hide 
Range on Protein: 76-113
Range on HMM: 104-140/140
Sequence Identity: 42% (16 aa)

QVCQGLQYLHRKEIVHGDLNLKNIEINPANNEIQLMNM
|. | ..|||   |||||. ..|| || ...||...  
QILQAIDYLHEHNIVHGDIKFSNILIN-SKDEIKIIDF
Kinase 21877.AA RAF 76-99 62 2.6e-08 22.74 In-house 111-134 (282) Show / Hide 
Range on Protein: 76-99
Range on HMM: 111-134/282
Sequence Identity: 62% (15 aa)

QVCQGLQYLHRKEIVHGDLNLKNI
|||||. ||| |.|.| ||  .||
QVCQGMDYLHAKNIIHRDLKSNNI
Kinase 21877.AA RAF 76-99 62 3e-08 24.35 In-house 108-131 (275) Show / Hide 
Range on Protein: 76-99
Range on HMM: 108-131/275
Sequence Identity: 62% (15 aa)

QVCQGLQYLHRKEIVHGDLNLKNI
|.|||  ||| |.|.|.||  |||
QICQGMDYLHAKNIIHRDLKSKNI
Kinase 21877.AA KSR 76-99 62 2.9e-07 20.83 In-house 107-130 (272) Show / Hide 
Range on Protein: 76-99
Range on HMM: 107-130/272
Sequence Identity: 62% (15 aa)

QVCQGLQYLHRKEIVHGDLNLKNI
| |||  ||| |.|.|.||  |||
QICQGMGYLHAKGIIHKDLKSKNI
Kinase 21877.AA Ciliate-E3 135-161 40 8.2e-07 17.6 In-house 176-202 (202) Show / Hide 
Range on Protein: 135-161
Range on HMM: 176-202/202
Sequence Identity: 40% (11 aa)

SPEQKQEENISYSSDLYSLGVLALSLY
.||| .. .||  ||.||.|.  . | 
APEQNDQQQISKESDYYSVGAVFCQLC
Kinase 21877.AA TKL 76-99 34 5e-06 17.7 In-house 140-171 (364) Show / Hide 
Range on Protein: 76-99
Range on HMM: 140-171/364
Sequence Identity: 34% (11 aa)

QVCQGLQYLHR--------KEIVHGDLNLKNI
....|..|||         . |.| ||. |||
DIARGMNYLHSMNPKWCTKPPIIHRDLKSKNI
Kinase 21877.AA TK 76-99 36 1.1e-05 14.17 In-house 242-271 (486) Show / Hide 
Range on Protein: 76-99
Range on HMM: 242-271/486
Sequence Identity: 36% (11 aa)

QVCQGLQYLHRK------EIVHGDLNLKNI
|...|..|||.|       .||.||   |.
QIACGMEYLHSKNCEFIQNFVHRDLAARNC
Kinase 21877.AA Pkinase_Tyr 76-94 42 0.000468 14.36 Pfam 119-137 (270) Show / Hide 
Range on Protein: 76-94
Range on HMM: 119-137/270
Sequence Identity: 42% (8 aa)

QVCQGLQYLHRKEIVHGDL
|...|..||..| ..| ||
QIAKGMEYLESKNCIHRDL
Kinase 21877.AA Ciliate-E3 76-99 41 0.005279 5.55 In-house 111-134 (202) Show / Hide 
Range on Protein: 76-99
Range on HMM: 111-134/202
Sequence Identity: 41% (10 aa)

QVCQGLQYLHRKEIVHGDLNLKNI
|. ||.  .| | | |.|..  ||
QIIQGMIAIHEKNIIHSDIKPDNI
Kinase 21877.AA TK 174-206 29 0.003087 5.85 In-house 453-486 (486) Show / Hide 
Range on Protein: 174-206
Range on HMM: 453-486/486
Sequence Identity: 29% (10 aa)

PVHCPFGLYEK-LKALINQNPDSRPPIDDIIEAL
| |||  .|.  ..   . .|. ||  ... |.|
PPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase 21877.AA TKL 190-206 29 0.009498 5.74 In-house 348-364 (364) Show / Hide 
Range on Protein: 190-206
Range on HMM: 348-364/364
Sequence Identity: 29% (5 aa)

NQNPDSRPPIDDIIEAL
...|..||  ..|.. |
DHDPEKRPSFQEILKRL
Kinase 21877.AA KSR 190-206 35 0.079309 2.01 In-house 256-272 (272) Show / Hide 
Range on Protein: 190-206
Range on HMM: 256-272/272
Sequence Identity: 35% (6 aa)

NQNPDSRPPIDDIIEAL
...|..||   ||   |
SYEPQERPTFQDIMKML
Kinase 21877.AA RAF 189-206 22 0.17774 0.85 In-house 258-275 (275) Show / Hide 
Range on Protein: 189-206
Range on HMM: 258-275/275
Sequence Identity: 22% (4 aa)

INQNPDSRPPIDDIIEAL
....|..||   .| . .
WSYQPEERPSFQQIMKMI
Kinase 21877.AA Pkinase_Tyr 190-206 35 1.727085 2.28 Pfam 254-270 (270) Show / Hide 
Range on Protein: 190-206
Range on HMM: 254-270/270
Sequence Identity: 35% (6 aa)

NQNPDSRPPIDDIIEAL
...|. ||   .|.| |
HYDPEDRPTFSEIHEQL
WD40 21877.AA WD40 363-401 22 1e-06 21.98 Pfam 1-39 (39) Show / Hide 
Range on Protein: 363-401
Range on HMM: 1-39/39
Sequence Identity: 22% (9 aa)

MKTLHYYQDHESLITSIASDST-HNYIFTSSLDGSVIVYQ
 | .| .  |.. .|..| .    .|....| ||.. .. 
WKCKHTF-GHTHWVTCCAWHPDMGHYLASGSRDGTIRIWD
WD40 21877.AA WD40 362-401 18 2e-06 28.8 SMART 1-46 (46) Show / Hide 
Range on Protein: 362-401
Range on HMM: 1-46/46
Sequence Identity: 18% (9 aa)

PMKTLHYYQDHES--LITSIASDSTH------NYIFTSSLDGSVIVYQ
. | .| .. |..   .|... ....      ||....| ||.. .. 
T-KCVHTFKGHTGNSWVTCVCWHPDGGSDDYPNYLASGS-DGTIRIWD
WD40 21877.AA WD40 408-447 18 0.007318 13.84 SMART 1-46 (46) Show / Hide 
Range on Protein: 408-447
Range on HMM: 1-46/46
Sequence Identity: 18% (9 aa)

QLKQHKKLSDFVY--GVSQVKVTADN------NYLIASDLSSNIYIYS
. |. ....      .|. |..  |.      |||....  ..|.|..
T-KCVHTFKGHTGNSWVTCVCWHPDGGSDDYPNYLASGS-DGTIRIWD
WD40 21877.AA WD40 409-447 17 1.912708 3.9 Pfam 1-39 (39) Show / Hide 
Range on Protein: 409-447
Range on HMM: 1-39/39
Sequence Identity: 17% (7 aa)

LKQHKKLSDFVYGVSQVKVTAD-NNYLIASDLSSNIYIYS
 |. ...    ..|. ...  |  .||. .   ..| |..
WKCKHTF-GHTHWVTCCAWHPDMGHYLASGSRDGTIRIWD
WD40 21877.AA WD40 538-574 25 6e-06 19.72 Pfam 1-39 (39) Show / Hide 
Range on Protein: 538-574
Range on HMM: 1-39/39
Sequence Identity: 25% (10 aa)

ITPIKEFNYHNNAITQISIGAN---YFAVSSQDKNISIFD
 .....|  |....| ...  .   |.| .| |..| |.|
WKCKHTF-GHTHWVTCCAWHPDMGHYLASGSRDGTIRIWD
WD40 21877.AA WD40 537-574 20 0.000502 20.62 SMART 1-46 (46) Show / Hide 
Range on Protein: 537-574
Range on HMM: 1-46/46
Sequence Identity: 20% (10 aa)

LITPIKEFNYHNN--AITQISIGAN--------YFAVSSQDKNISIFD
  .....|. |..  ..| ...  .        |.|..| |..| |.|
T-KCVHTFKGHTGNSWVTCVCWHPDGGSDDYPNYLASGS-DGTIRIWD
WD40 21877.AA WD40 576-615 18 0.500136 2.26 SMART 1-46 (46) Show / Hide 
Range on Protein: 576-615
Range on HMM: 1-46/46
Sequence Identity: 18% (9 aa)

QLNKIQSISTHLD--CVANVFIDKDC------NSLTSNGWDGSTCLFL
. . ..... | .   |  | .. |       | | | . ||. ... 
T-KCVHTFKGHTGNSWVTCVCWHPDGGSDDYPNYLASGS-DGTIRIWD