Gene 23577 (Tetrahymena)
23577
Group:
Other
Family:
Ciliate-Unique
Sequence
Protein domains of 23577.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 23577.AA | Ciliate-A1 | 196-232 | 43 | 1.7e-09 | 28.42 | In-house | 106-142 (301) | Show / Hide |
Range on Protein: 196-232 Range on HMM: 106-142/301 Sequence Identity: 43% (16 aa) LCLTIIEAVTSLHVSNIFHGDIKPQNIIIFYKNGFKL .|. ||| . ..| || | |.|||||.| .. .|. ICYQIIEGYADIHDHNILHRDLKPQNILIHFDDKWKI |
|||||||||
| Kinase | 23577.AA | Other-Unique | 112-329 | 11 | 5.6e-09 | 27.25 | In-house | 1-249 (249) | Show / Hide |
Range on Protein: 112-329 Range on HMM: 1-249/249 Sequence Identity: 11% (29 aa) SKGGYSDVCIVKDQKDRKLIRKKVTNPSAFLNELRFFQQMENEYLVNIYYYS-----------KCDQEFYLEKGDETLYSFFKKN-----TIKNRFFLFL | .. .. . .. .....| . . . ... . . ..|... .||.|. .|.. |..|. .... ..... . .... ... IKDIGKGTYGRVYKQHHNKKKKYCAKKTKHHKI-HCMDMDNNKRE-QIYHYQIIHCIFYWTMNHCHLCFCYEHCPNMIFYIMYPWYHHHCECQCQCEHWM LCLTIIEAVTSLHVSNIFHGDIKPQNIIIF------YKNG-------------FKLDNLQQDQDICIKDIQQFLAIESFLKFDFEGFQGSPDYKFVDNEN |. .|.. ..|| .|..|.||.|.||.| .|. .|. .... . .. ...| .. . .|.. . . ... NCCHMIHNLHHLHNNNHIHCDINPNNIWINQNNIHMCHNCGHNIPTIIIEHQHIKIMDFNNN-N-MMYFAPEF-SCRWCSPETFDYWPLGEKIDQYHFGC INFSDL--FNAIYRNSHKEE--IKQNYKSFSQMLEKLFCVTIKFIDFQSSSKLNSVQ ..|. ... ..... . .....|. ..| .. . .... . ....|... YHFHMNCQHWIFHYHDV-QHWPPHESPKDI-HILICQCECCHQCM-VNPYQNPNCFY |
|||||||||
| Kinase | 23577.AA | Ciliate-B2 | 201-232 | 34 | 7.3e-08 | 14.47 | In-house | 114-145 (197) | Show / Hide |
Range on Protein: 201-232 Range on HMM: 114-145/197 Sequence Identity: 34% (11 aa) IEAVTSLHVSNIFHGDIKPQNIIIFYKNGFKL |.. . ... || | ||||||| . ... ... IDGLIQFRMYNILHLDIKPQNILFMQNGNYVY |
|||||||||
| Kinase | 23577.AA | VPS15 | 200-224 | 34 | 4.5e-07 | 20.65 | In-house | 107-132 (296) | Show / Hide |
Range on Protein: 200-224 Range on HMM: 107-132/296 Sequence Identity: 34% (9 aa) IIEAVTSLHVSN-IFHGDIKPQNIII . .|. .|... ..|||||..||.. TLCALEQCHKQGNVCHGDIKSENILV |
|||||||||
| Kinase | 23577.AA | Ciliate-A5 | 193-232 | 37 | 5.4e-07 | 20.38 | In-house | 101-140 (275) | Show / Hide |
Range on Protein: 193-232 Range on HMM: 101-140/275 Sequence Identity: 37% (15 aa) LFLLCLTIIEAVTSLHVSNIFHGDIKPQNIIIFYKNGFKL |... ..| .. |. .||.||||.||||.. . .|| LWYIMDCLISVCMYLQQNNICHGDIRPQNICLTQDGQVKL |
|||||||||
| Kinase | 23577.AA | MOS | 198-224 | 44 | 8.6e-07 | 18.32 | In-house | 121-147 (299) | Show / Hide |
Range on Protein: 198-224 Range on HMM: 121-147/299 Sequence Identity: 44% (12 aa) LTIIEAVTSLHVSNIFHGDIKPQNIII | .. |.. .| || | |.||.|||. LDVVNALQYCHHQNILHLDVKPANIIV |
|||||||||
| Kinase | 23577.AA | Ciliate-E2 | 200-243 | 35 | 1e-06 | 18.51 | In-house | 169-197 (365) | Show / Hide |
Range on Protein: 200-243 Range on HMM: 169-197/365 Sequence Identity: 35% (16 aa) IIEAVTSLHVSN-IFHGDIKPQNIIIFYKNGFKLDNLQQDQDICI ||.|. .|| | |.| ||||.||.. |.| IILALEYLHSKNNIIHRDIKPENILF----------------IKI |
|||||||||
| Kinase | 23577.AA | Ciliate-E3 | 196-224 | 44 | 2e-06 | 16.51 | In-house | 108-136 (202) | Show / Hide |
Range on Protein: 196-224 Range on HMM: 108-136/202 Sequence Identity: 44% (13 aa) LCLTIIEAVTSLHVSNIFHGDIKPQNIII .| ||. . .| || |.||||.|| . ICIQIIQGMIAIHEKNIIHSDIKPDNILV |
|||||||||
| S_TKc | 23577.AA | S_TKc | 106-378 | 13 | 3e-06 | -86.02 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 106-378 Range on HMM: 1-231/231 Sequence Identity: 13% (43 aa) NEKLDY-SKGGYSDVCIVKDQK-DRKLIRKKVTNPSAFLNELRFFQQMENEYLVNIYYYSKCDQEFYL--EKGDE---TLYSFFKKNTI------KNRFF |.|. ||... |. ... | .|. |.. ...|.. .. ...|..|.. ...|. | | .|... ||. . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-H LFLLCLTIIEAVTSLHVSNIFHGDIKPQNIIIFYKNGFKLDNLQQDQDICIKD------------IQQFLAIESFLKFDF-------------EGFQGSP .. |..|. .| .| | |.||.|| . | | | ..| | . .... | . | | ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------------HIKICDFGLARQLTTFCGTPWYMAPEVL-GYGKCKCDWWSCGCILYEMLCGYP DYKFVDNENINFSDLFNAIYRNSHKEEIKQNYKSFSQMLEKLFCVTIKFIDFQSSSKLNSVQKICYYTKAFTCKKFINKMKSEYLNFLDKMYVDHYS--- . . .|. | .| ..|..|. . . PFP-------QMQMMFKKIG------------------------------------------------------------SPEAKDFIRKCLQKDPEKRP TFRTILM----ILNFQYI | .| | . ... TA-EALQDEWDIKCHPWF |
|||||||||
| Kinase | 23577.AA | Ciliate-C3 | 200-235 | 44 | 4e-06 | 18.43 | In-house | 105-140 (140) | Show / Hide |
Range on Protein: 200-235 Range on HMM: 105-140/140 Sequence Identity: 44% (16 aa) IIEAVTSLHVSNIFHGDIKPQNIIIFYKNGFKLDNL |. |. || || |||||..||.| |. |. ILQAIDYLHEHNIVHGDIKFSNILINSKDEIKIIDF |
|||||||||
| Kinase | 23577.AA | TKL-Sp1 | 200-224 | 48 | 4e-06 | 14.58 | In-house | 107-131 (263) | Show / Hide |
Range on Protein: 200-224 Range on HMM: 107-131/263 Sequence Identity: 48% (12 aa) IIEAVTSLHVSNIFHGDIKPQNIII . ||| .| .|| | |||| |... VLQAVTFMHACNILHLDIKPANVMV |
|||||||||