Gene 18315 (Tetrahymena)
18315
Sequence
Protein domains of 18315.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 18315.AA | ULK | 4-256 | 30 | 4.1e-88 | 299.04 | In-house | 1-329 (329) | Show / Hide |
Range on Protein: 4-256 Range on HMM: 1-329/329 Sequence Identity: 30% (102 aa) YHIYEDIAKGKYSIIYKARKKKT----IDYFAVKSME--KCKRKK-----------LMNEVKIFNLLD--------HVNILKYYNWYETK--NHLWAIFE |.. . . || . ||.|.||| ..|.| .. |...|. |.||.|| |. | || |.| |.||. |... |.| YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME YSSGGNLLSLIEQDKK----------LTEPQIKIFAKDLIQGLLYLHSKGIIYCDLKPSNILLNEY------------GTLKYCDFGLARQ-IVD----- | ||.| ..|...|| |.|.....| |....|. .||...|| .|.||.|||... |.|| .|||.|.. | YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ -LIQTD-EDVKEGSKK---GTPYYMAPELFQDDG----VYSYQSDLWSLGCILYELSNGKPPFVSKSFQDLVWLIINKE--------------PEVVEG- . . | | |||.||||...|. | |.| .|.||||||.||. |||||.. |.|....||.|. | . MMMTCVNE-------KRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKD -----FSSDFHSFVFGLLQKNPLKRLNWSEIINHPFL .|...... ..||... .| .| |..|||.. GNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF |
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Kinase | 18315.AA | S_TKc | 4-256 | 33 | 1.3e-85 | 291.65 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 4-256 Range on HMM: 1-231/231 Sequence Identity: 33% (89 aa) YHIYEDIAKGKYSIIYKARKKKTIDYFAVKSMEKCKRKKLMNEVKIFNLLDHVNILKYYNWYETKNHLWAIFEYSSG--GNLLSLIEQDKK------LTE |.| . | || .. ||.|.||| ..|.| . .....|..| .| || |.| .... .||. ..|| .| |.|...|.. .. ..| YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE PQIKIFAKDLIQGLLYLHSKGIIYCDLKPSNILLNEYGTLKYCDFGLARQIVDLIQTDEDVKEGSKKGTPYYMAPELFQDDGVYSY-QSDLWSLGCILYE ... ... ....| |.||.|||..||||.||||.| ..| ||||||||. . |||.|||||.. |.. .| ||.|||||| -HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYE LSNGKPPFVSKSFQDLVWLIINKEPEVVEGFSSDFHSFVFGLLQKNPLKRLNWSEIIN-------HPFL . |.||| | . .| |... .|. ..|||.| ||. |. . ||.. MLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | 18315.AA | ULK | 4-256 | 30 | 1.2e-84 | 287.55 | In-house | 1-324 (324) | Show / Hide |
Range on Protein: 4-256 Range on HMM: 1-324/324 Sequence Identity: 30% (101 aa) YHIYEDIAKGKYS-IIYKARKKKT---IDYFAVKSMEKCKRKK-------------LMNEVKIFNLLD---HVN--ILKYYNWYETK--NHLWAIFEYSS | . . . || . ||.|.||| |.|.| ..|.| .| |.||..| |. |.| | |.| |.||. |... |.|| YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN GGNLLSLIEQDKK---------LTEPQIKIFAKDLIQGLLYLHSKGIIYCDLKPSNILLNEY------------GTLKYCDFGLARQI-------VDLIQ ||.| ..|...|| |.|.....| |....|. .||...|| .|.||.|||... |.|| .|||.|... .. . GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT TD-EDVKEGSKK---GTPYYMAPELFQDDG----VYSYQSDLWSLGCILYELSNGKPPFVSKSFQDLVW--------------LIINKEPEVV-----EG . | | |||.||||...|. | |.| .|.||||||.||. ||.||.| |.|... .| |. . CVNE-------KRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPK FSSDFHSFVFGLLQKNPLKRLNWSEIINHPFL .|...... ..||... .| .| ||.|||.. ISPECKDLIRRMLQYDEKDRISWEEIFNHPWF |
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Kinase | 18315.AA | AGC | 4-256 | 22 | 4e-83 | 213.97 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 4-256 Range on HMM: 1-395/395 Sequence Identity: 22% (88 aa) YHIYEDIAKGKYSIIYKARKK------KTIDYFAVKSMEKCK---------RKKLMNE------------VKIFNLLD----------HVNILK-YYNWY .... | || .. | .||| | .|.|.| ..| . .. |.| .|. ... | .| | . . FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF ETKNH--LWAIFEYSS---------GG-NLLSLIE---QDKKLTEPQIKIFAKD-------LIQGLLYLHS-KGIIYCD-LKPSNILLNEYGTLKYCDFG ..|.| | . || . || |.. . . ....|......| .. .| |||| .|||. | ||| ||||.| | .| .||| QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG LARQIVD-----------------------------------LIQTD----------EDVKEGSKKG--TPYYMAPELFQDDGVYSYQSDLWS--LGCIL |. .... . .. .... . | || ||||| . |... | || |||.. LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----YGKACDWWSFGLGCLM YELSNGKPPFVSKS----------FQDLVWLII------NKEPEVV----------EGFSSDFHSFVFGLLQKNPLKRLN----------WSEIINHPFL ||. |.||| ... .. .|. |.... . ||.. ... .||.|.| ||| .|| |||. YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF |
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Kinase | 18315.AA | Pkinase | 4-256 | 30 | 4.6e-76 | 263.82 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 4-256 Range on HMM: 1-293/293 Sequence Identity: 30% (90 aa) YHIYEDIAKGKYSIIYKARKKKTIDYFAVKSMEKCKRKKLMN-------EVKIFNLLDHVNILKYYNWYETKNHLWAIFEYSSGG----NLLSLIE--QD ||| . | .| .. ||...|.| . .||| ..|...|. .. |..| . |.| ||...| |.|.|.|.. ..|| || | ..|. .. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH KKL--TEPQIKIFAKDLIQGLLYLHSKGIIYCDLKPSNILLNEYGTL----KYCDFGLARQIVDLIQTDEDVKEGSKKGTPYYMAPELFQDDGVYSYQSD ... .| ..| ... ...|| |.||.|||..||||.|||... |.. | ||||||.|. . .. . |||.|||||. ... |.. .| GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD LWSLGCILYELSNGKPPFVSK----SFQDLVWLIINKEPEVVEGFS------------------------SDFHSFVFGLLQKNPLKRLNWSEIINHPFL ||.||||||. .|.||| .. . | ..| .. . .. . ... .|. ..|.|.| ||... .| .||.. MWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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Kinase | 18315.AA | CAMK | 9-256 | 18 | 8.9e-67 | 213.95 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 9-256 Range on HMM: 1-425/425 Sequence Identity: 18% (80 aa) DIAKGKYSIIYKARKKKTI------------DYFAVKSMEKC-------------------------------KRKKLMNEVKIFNL-------LDHVNI . .| ... .... |.| .|.| ..| .||....|..| .. ||| || TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI LKYYNWYE------------TKNH--------LWAIF---EYSSGG----NLLSLIEQD---------------KKLTEPQIKIFAKDLIQGLLYLHSKG .| | .|| | .. .. .. || ||| |.. | . ...|| . . . . ..... |.||.. IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN IIYCDLKPSNILLNEY-----------------GTLKYCDFGLARQIVDLI------------------QTDEDVKEGSKKGTPYYMA-PELFQD----- |. .|||| ||||.. ...| .|||.|... . ...|. | |||.||| ||... IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN --------DGVYSYQSDLWSLGCILYELSNGKPPFVSK-------------SFQDLVWLIINKEPE-VVEGFSS-----------------------DFH |....| ||.|.||| . |.||| .. . ..| |.. . . . || . MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK SFVFGLLQKNPLKRLNWSEIINHPFL ... ..||..| ||.. ... |||.. DLIRKMLQVDPEKRMTIEQCLNHPWM |
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Kinase | 18315.AA | STE | 4-256 | 25 | 1.7e-66 | 227.23 | In-house | 1-359 (359) | Show / Hide |
Range on Protein: 4-256 Range on HMM: 1-359/359 Sequence Identity: 25% (94 aa) YHIYEDIAKGKYSIIYKARKKK---------------TIDYFAVKSME--------------------KCKRKKLMNEVKIFNLLD--HVNILKYYNWYE . . | | || . |||...| | ...|.| |. . .......|.|| . .. | || ||| |. WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF TK-------NHLWAIFEYSSGGNLLSLIE---QDKK-LT----------EPQIKIFAKDLIQG-LLYLHSKGIIYCDLKPSNILLNEYGTLKYCDFGLAR . ..|| . || .|| | ..|. .| |. |.||.........| | ||||..|| |.||.|||| | ||||.. KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG QIVDLIQ-----------TDEDVKEGSKKGTPYYMAPELFQD-----DGVYSYQSDLWSLGCILYELSNGKPPFVSKSFQDLVWLII------------- |..| . . . | . ||| .|||| | |. |....| ||||| . |. .||||. . ..|. QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC ---NKEPEVVE-------------------GFSSDFHSFVFGLLQKNPLKRLNWSEIIN--HPFL .. | . .|..|. |. |||.| || . |. .. |||. IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI |
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Kinase | 18315.AA | Ciliate-E2 | 4-256 | 23 | 3.8e-65 | 222.56 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 4-256 Range on HMM: 1-365/365 Sequence Identity: 23% (90 aa) YHIYEDIAKGKYSIIYKARKKKT-----------------------IDYFAVKSMEKCKRKKLMNEVKIFN----------------LLDHVNILKYYNW | . . | .| ....||....|. | ..|.|.|.| . . ...| .|.. .|.| ||.|.| . YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC YE--TKNHLWAIFEYSSGGNLLSLIE------------QDKKLTEPQIKIFAKDLIQ---------------GLLYLHSKG-IIYCDLKPSNILLNEYGT .. ..|.. ..|| .||.|...|. . |..|| .|| . | ..| .| |||||. ||. |.||.|||. FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----- LKYCDFGLARQIVD------------LIQTDEDVKEGSKK---------------GTPYYMAPELFQDDGV--------YSYQSDLWSLGCILYELSNGK .| .||||.... | ... .... |||.||||| .. . |.|..|.||||.||||. || IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK PPFVSKSFQDLVWLIINKEPEVV--------------------EGFSSDFHSFVFG----LLQKNPLKRLN-WSEIINHPFL ||| ....|. .. . | . . .|||.| ||.. |..|.|||.. PPF----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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Kinase | 18315.AA | Fused | 4-256 | 36 | 8.8e-56 | 189.96 | In-house | 1-251 (251) | Show / Hide |
Range on Protein: 4-256 Range on HMM: 1-251/251 Sequence Identity: 36% (95 aa) YHIYEDIAKGKYSIIYKARKKKTIDYFAVKSMEKCKR-----KKLMNEVKIFNLLDHVNILKYYNWYETKNHLWAIFEYSSGGNLLSLIEQDKKLTEPQI ||. | . .| . .||||.| |.| | | | | |. | . | .| . .||. . .. .| ..| | | |. | |. YHVSEMVGQGSFGCVYKARRKYDSKVVAIKFIPKRGRSDKELKNLRRECEIMRRMHHPHIIHMIDSFETDKEVVVVTDYAE-MELHQYLEYDGKMPEEQV KIFAKDLIQGLLYLHSKGIIYCDLKPSNILLNEYGTLKYCDFGLARQ--IVDLIQTDEDVKEGSKKGTPYYMAPELFQDDGVYSYQSDLWSLGCILYELS . | |. | |||| | |.|| |||| . | ||||.|| | .. | | |||| |||||| | |.|||||||||| RRIACHLVSALYYLHSHRILHRDMKPQNILLDKNMHIKLCDFGFARNMSINTHVLT-------SIKGTPLYMAPELVEEQP-YDHHADMWSLGCILYELM NGKPPFVSKSFQDLVWLIINKEPEVVEGFSSDFHSFVFGLLQKNPLKRLNWSEIINHPFL |.||| | || .|. . .| . .| ||| | | .|. | . ||| VGQPPFCANSIFHLVSMIKHDDVKWPSTITSCCRNFLQGLLTKDPRHRISWPQLLCHPFV |
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Kinase | 18315.AA | STE20 | 4-256 | 32 | 1.6e-55 | 190.73 | In-house | 1-288 (288) | Show / Hide |
Range on Protein: 4-256 Range on HMM: 1-288/288 Sequence Identity: 32% (95 aa) YHIYEDIAKGKYSIIYKARKKKTIDY----FAVKSMEK-------CKRKKLMNEVKIFNLLDHVNILKYYNWYETK----NHLWAIFEYSSGGNLLSLIE | ..| | .| | .|||..|.| .| |.| |. .... ...|. | . ..| || |||. | . ..|| . || .|| |. ... YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK ---QDKK------LTEPQIKIFAKDLIQGLLYLHSKGIIYCDLKPSNILLNEYGTLKYCDFGLARQIVDLIQTDEDV---KEGSKKGTPYYMAPELFQD- ..| ..|.|| ... ||| ||||..|| |.| ||||.| | | .|||.. |. .. . . . | . ||||.||||. | HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHG-R-D-TMQFKRNTFVGTPYWMAPEVIQCM ---DGVYSYQSDLWSLGCILYELSNGKPPFVS-KSFQDLVWLI--INKEPEVVE----GFSSDFHSFVFGLLQKNPLKRLNWSEIINHPFL |. | | .| |||| . |. .|.||. .. . . |. |. . .|..|| || |||.| || |. .|||. EGPDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI |
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Kinase | 18315.AA | Ciliate-E2-Unclassified | 4-256 | 24 | 5e-55 | 189.13 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 4-256 Range on HMM: 1-352/352 Sequence Identity: 24% (87 aa) YHIYEDIAKGKYSIIYKARKKKTIDYF-----AVKSMEKCKRKKL-----------MNEVK-------------IFNLLDHVNILKYYNWYETKNHLWAI |.| . | .| ....||...||. .. . |.... ..... ||. | |. ..| .|.|.. . ..|... . YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV FEYSSGGNLLSLIEQDKK-----------------LTEPQIK-----IFAKDLIQGLLYLHSKG-IIYCDLKPSNILLNEYG---TLKYCDFGLARQIVD || ||.|. |.. || .|| |.| ... ..||| |||.|. ||. |.||.|||... | .| .|||..... . MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ LIQTDEDV----------KEGSKK-GTPYYM----APELFQDDGVYS---YQSDLWSLGCILYELSNGKPPFVSKSFQD----------------LVWLI .. | . .. . . |||.|| |||..| . . |..| ||||.||||. |..|| ... . | | NNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI INKEPEVVE--------GFSSDFHSFVF----GLLQKNPLKRLNWSEIINHPFL ..|.... . . | |. .|.||| ||.....|.|||.. KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF |
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Kinase | 18315.AA | RSK | 6-256 | 25 | 1.5e-51 | 177.56 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 6-256 Range on HMM: 1-278/278 Sequence Identity: 25% (71 aa) IYED--IAKGKYSIIYKARKKKTIDYFAVKSMEKCKRKKL-------MNEVKIFNLLD-HVNILKYYNWYETKNHLWAIFEYSSGGNLLSLIEQDKK--- . .. ...||... | . ..| ..|.| .| |... | |..| . | .| ... ..|. .|. | || .|| |. ... | LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC LTEPQIKIFAKDLIQGLLYLHSKGIIYCDLKPSNILLNE---YGTLKYCDFGLARQIVDLIQTDEDVKEGSKKGTPYYMAPELFQ---DDGVYSYQSDLW ..| .. . .. . .||..|||. ||||.|||... |..| .|||...| |. . . .| |||||. .| .. . |.| FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF----RCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWW SLGCILYELSNGKPPFVS---KSFQDLVWLIINKE--PEVV--EGFSSDFHSFVFGLLQKNPLKRLN-----WSEIINHPFL |||...||. |.||| . .. ... | ... .. . | .. ... ..|...| |||. .|| .||.. SLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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Kinase | 18315.AA | Pkinase_Tyr | 31-214 | 28 | 2.1e-17 | 59.56 | Pfam | 32-228 (270) | Show / Hide |
Range on Protein: 31-214 Range on HMM: 32-228/270 Sequence Identity: 28% (57 aa) AVKSMEKCKRKK------LMNEVKIFNLL-DHVNILKYYNWYE-TKNH--LWAIFEYSSGGNLLSLIEQ----DKKLTEPQIKIFAKDLIQGLLYLHSKG |||.. .. .|.|.|| | .| ||...| . . .. ..|| .|.||. . ...|| ... .. . .|. ||.||. AVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN IIYCDLKPSNILLNEYGTLKYCDFGLARQIVDLIQTDED-VKEGSKKGTPYYMAPELFQDDGVYSYQSDLWSLGCILYELSN-GKPP-FVSKSFQDLVWL .| || |.|..| .. | ||||||| | .|. .| |. | |||| ... .. .|| || | ..|. |. | . | .... . CIHRDLAARNCLVTENNVVKICDFGLARDI---YNDDYYYRKRGGGKLPIKWMAPECINYGK-FTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEY I | I |
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Kinase | 18315.AA | TyrKc | 4-256 | 23 | 4.8e-17 | 52.88 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 4-256 Range on HMM: 1-280/280 Sequence Identity: 23% (68 aa) YHIYEDIAKGKYSIIYKARKKKTIDYFAVKSMEKCKRKKLMNEVKIFNLL--DHVNILKYYNWYETK-------NHLWAIFEYSSGGNLLSLIEQDKK-L . . . | . ..||.. | |||.. ...|. .|.| .| | .| ||.. | .. |. ..|| ..|.|.. . .. | ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKL TEPQIKIFAKDLIQGLLYLHSKGIIYCDLKPSNILLNEYGTLKYCDFGLARQIVDL----IQTDEDVKEG--SKK--GTPYYMAPELFQDDGVYSYQSDL . .. |. . .| |||||..| || |.|..| .| | .||||.| | | .| .| . ..| |||| . ..|... .|| CMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFTTKSDV WSLGCILYEL-SNGKPPFVS-----KSFQDLVWLIINK-EPEVVEG--------FSSDFHSFVFGLLQKNPLKRLNWSEIINHPFL || | ..|. ..|..| .| |... .. . .. . ... .. . .| .| . ||| | .. WSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF |