Gene PKN (Sea Urchin)

PKN

Species: Sea Urchin
Alias: Spk022, PKN, SPU_009681
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: AGC
Family: PKN

Sequence

Name Sequence Type Origin Length Description Download
PKN.AA Protein None 863 None Fasta, JSON
PKN.kin_dom Protein Kinase Domain None 260 None Fasta, JSON

Protein domain

Protein domains of PKN.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HR1 PKN.AA HR1 1-30 46 0.000446 17.75 Pfam 46-74 (74) Show / Hide 
Range on Protein: 1-30
Range on HMM: 46-74/74
Sequence Identity: 46% (14 aa)

MLQDSKTKIEFIRMQILKTQQAQQSRQIPT
||..|..|||..|||. | || .|  ..|.
MLRESNQKIEYLRMQLEKLQQRHQD-HPPN
HR1 PKN.AA HR1 58-97 19 6.9e-07 27.84 Pfam 1-42 (74) Show / Hide 
Range on Protein: 58-97
Range on HMM: 1-42/74
Sequence Identity: 19% (8 aa)

FRVEEVRHHYKVELALVEGFKNVIKMY--NNAKTSDKKGLAE
 | ...|..  .|... ||..|....|  .... ...| ...
QRLQQLRKKIEREMKIKEGAENMRRAYQMTTDNKKHRKVRQQ
HR1 PKN.AA HR1 122-194 24 4.5e-17 64.35 Pfam 1-74 (74) Show / Hide 
Range on Protein: 122-194
Range on HMM: 1-74/74
Sequence Identity: 24% (18 aa)

FRVEEVRHHYKVELALVEGFKNVIKMY--NNAKTSDKKGLAEAQKGLVEASHKLDILREGLEKRIQELPPDQTRF
 | ...|..  .|... ||..|....|  .... ...| ....|. | |.. |.. ||. |||. |.... ..  
QRLQQLRKKIEREMKIKEGAENMRRAYQMTTDNKKHRKVRQQCQQMLRESNQKIEYLRMQLEKLQQRHQD-HPPN
C2 PKN.AA C2 221-353 10 3e-06 27.85 SMART 1-92 (92) Show / Hide 
Range on Protein: 221-353
Range on HMM: 1-92/92
Sequence Identity: 10% (16 aa)

VLEVRIMGCQDLQEMIPYRARNSITSLNSPSESKGGILRGKASFHGRSSSRSSSTKEEISNEISAIMKLDSVLVGQTPFKPIS----NQCWDQ---KFLF
.|.|.|. ...|                                                    ....       .|  .. .    |  |..   .| |
TLTVHIIEARNLP------------------------------------------------DPYVKVY-------KTKVVKNTLSGFNPVWNEWMETFYF

NLDKARELEINVRWKDQRSLCAVKFLR-------------LEDFLDNQRHGMC
...  . |.. |  .  . .  . . .             |.| | ..|| ..
DVHP-Q-LRFEVWDH--DFIGHCCIPPNNPHWHQWDGCIHLSDIL-GYRH-WW
Kinase PKN.AA PKN 536-795 84 1e-205 689.69 In-house 1-260 (260) Show / Hide 
Range on Protein: 536-795
Range on HMM: 1-260/260
Sequence Identity: 84% (219 aa)

FRLISVLGRGHFGKVLLTEYKTTGEFFAIKALKKRDVVAREEVESLMCEKRIFEAANSIRHPFLVNLFACFQTEHHVCFVMEYAMGGDLMMHIHNDVFTE
||.|.||||||||||||..||.|||..|||||||.|.|||.|||||||||||||..|..|||||||||||||||.|||||||||||||||||||.|||.|
FRCIAVLGRGHFGKVLLSQYKHTGEYYAIKALKKQDIVARDEVESLMCEKRIFEVVNRMRHPFLVNLFACFQTEEHVCFVMEYAMGGDLMMHIHEDVFSE

PRTVFYSACVVLGLQYLHENKIVYRDLKLDNLLLDQDGFLKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTEPYYTRAVDWWGLGVLIFEMLVGESP
||..||.||||||||||||.||.||||||||||||..|..||||||||||||||||||||||||||||||||||. .||||||||||||||.||||||.|
PRACFYAACVVLGLQYLHEHKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLIYEMLVGECP

FPGDDEEEVFDSIVNDEVRYPRFLSTEAVAIMRRLLRRNPMRRLGSSQRDAEDIKMQGFF
|||||||||||.||||.||||||||.||.||||||||.||.||||...||||||||| ||
FPGDDEEEVFDCIVNDDVRYPRFLSVEAIAIMRRLLRKNPERRLGAGERDAEDIKMQPFF
Kinase PKN.AA AGC 536-795 32 1.4e-176 461.22 In-house 1-395 (395) Show / Hide 
Range on Protein: 536-795
Range on HMM: 1-395/395
Sequence Identity: 32% (128 aa)

FRLISVLGRGHFGKVLLTEYK------TTGEFFAIKALKKRD-VVARE--EVESLMCE------------KRIFEAANSIR-------HPFLVN-LFACF
|... |.|.|.|||| | . |      .||...|.| |||.. .| ..  .||  | |            ..|.| .|. .       |||.|. |. .|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTEHH--VCFVMEYAM---------GG-DLMMHIHND----VFTEPRTVFYSAC-------VVLGLQYLHE-NKIVYRD-LKLDNLLLDQDGFLKIADFG
|.. |  ..|||||.          || .|..|....    .|.|.|. || |.       .||.|.|||. ..|..|| ||..|.|||.|| .|..|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LCKEGMGYG--------------------------------------------------DRTSTFCG--TPEFLAPEVLTEPYYTRAVDWWG--LGVLIF
||||||..|                                                  |||.||||  |||..|||.|    |..|.|||.  ||.|..
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMLVGESPFPGD----------DEEEVFDSIV------NDEVRYP----------RFLSTEAVAIMRRLLRRNPMRRLGSSQRD-----AEDIKMQGFF
|||.| .|| ||          ...|.|..|       |..|..|          |..| ||. ....|| ..| .|||. ..|     ||.||   .|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase PKN.AA PKC 536-795 51 4.5e-146 476.59 In-house 1-262 (262) Show / Hide 
Range on Protein: 536-795
Range on HMM: 1-262/262
Sequence Identity: 51% (135 aa)

FRLISVLGRGHFGKVLLTEYKTTGEFFAIKALKKRDVVAREEVESLMCEKRIFEAANSIRHPFLVNLFACFQTEHHVCFVMEYAMGGDLMMHIHND-VFT
|... |||.| ||||.| | | | |..|||.|||  ..  . ||. |.|||... |.   ||||..|. ||||. .  |||||  ||||| || .   | 
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWK--HPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFK

EPRTVFYSACVVLGLQYLHENKIVYRDLKLDNLLLDQDGFLKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTEPYYTRAVDWWGLGVLIFEMLVGES
|....||.| ....||.|||. |.|||||||| |||..|  ||||||.|||.| .||.||||||||...|||.| .  |. .|||| .||| .||..| |
EEHARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQS

PFPGDDEEEVFDSIVNDEVRYPRFLSTEAVAIMRRLLRRNPMRRLGSSQRD---AEDIKMQGFF
|| |.||.|.|.|| .|...||| || |||.|.  .. .|| .|||. ...   ..||.   ||
PFHGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase PKN.AA Akt 536-795 42 3.5e-117 376.16 In-house 1-264 (264) Show / Hide 
Range on Protein: 536-795
Range on HMM: 1-264/264
Sequence Identity: 42% (113 aa)

FRLISVLGRGHFGKVLLTEYKTTGEFF-AIKALKKRDVVAREEVESLMCEKRIFEAANSIRHPFLVNLFACFQTEHHVCFVMEYAMGGDLMMHIHND-VF
|... |||.| ||||.| . | |.... |.|.|||.  ... .||  . |..| .  |   |||.|||   |||... .|||.|. ||.|  |.. . .|
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCN---HPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRF

TEPRTVFYSACVVLGLQYLHENKIVYRD-LKLDNLLLDQDGFLKIADFGLCKEG-MGYGDRTSTFCGTPEFLAPEVLTEPYYTRAVDWWG-LGVLIFEML
.|.|. || | ..|....||.. |.||| ||. |.|.|.|| ....|||||||. . ..|.| ||||||| ||||.|    .|.|||||| ||....||.
SEDRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMM

VGESPFPGDDEEEVFDSIVNDEVRYP--RFLSTEAVAIMRRLLRRNPMRRLGSSQRDAEDIKMQGFF
 |  ||  .| .. |. | | .|..|  ...| |.  . ..|| ..| .|||.   ||..||   .|
CGRPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase PKN.AA Eta 536-795 49 1.3e-113 383.8 In-house 1-261 (261) Show / Hide 
Range on Protein: 536-795
Range on HMM: 1-261/261
Sequence Identity: 49% (130 aa)

FRLISVLGRGHFGKVLLTEYKTTGEFFAIKALKKRDVVAREEVESLMCEKRIFEAANSIRHPFLVNLFACFQTEHHVCFVMEYAMGGDLMMHIHND-VFT
|  | |||.| ||||.| | | |.| .||| |||  ..  ..||  |.||||   |.  .|||| .|..||||.  . |||||  ||||| .|     | 
FNFIKVLGKGSFGKVMLAERKGTDEVYAIKVLKKDVIIQDDDVECTMTEKRILSLAR--KHPFLTQLHCCFQTKDRLFFVMEYVNGGDLMFQIQRARKFD

EPRTVFYSACVVLGLQYLHENKIVYRDLKLDNLLLDQDGFLKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTEPYYTRAVDWWGLGVLIFEMLVGES
|||. || | |.. |..||.. ..||||||||.|||..|  |.||||.||||.  |  |.||||||...|||.| |  |  .|||| .|||..||. |..
EPRARFYAAEVTCALMFLHQHGVIYRDLKLDNILLDHEGHCKLADFGMCKEGIMNGMTTTTFCGTPDYIAPEILQEMEYGPSVDWWAMGVLMYEMMCGQP

PFPGDDEEEVFDSIVNDEVRYPRFLSTEAVAIMRRLLRRNPMRRLGSS--QRDAEDIKMQGFF
||  | |...|.||..|.| || .|. |||.|..  . .|| .|||.   | . ..|.   ||
PFEADNEDDLFESILHDDVLYPVWLHKEAVSILKAFMTKNPHKRLGCMTAQGGEHAIRQHPFF
Kinase PKN.AA Delta 536-795 49 2e-113 383.12 In-house 1-259 (259) Show / Hide 
Range on Protein: 536-795
Range on HMM: 1-259/259
Sequence Identity: 49% (130 aa)

FRLISVLGRGHFGKVLLTEYKTTGEFFAIKALKKRDVVAREEVESLMCEKRIFEAANSIRHPFLVNLFACFQTEHHVCFVMEYAMGGDLMMHIHNDV-FT
| .  |||.| ||||.|.| | . ...|||.|||  |.  ..||. | |.|.   |   .||||  ||  |||..|. |||||  ||||| || .   | 
FHFHKVLGKGSFGKVMLAELKGKNKYYAIKCLKKDVVLEDDDVECTMVERRVLALA--WEHPFLCHLFCTFQTKEHLFFVMEYLNGGDLMYHIQQCHRFD

EPRTVFYSACVVLGLQYLHENKIVYRDLKLDNLLLDQDGFLKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTEPYYTRAVDWWGLGVLIFEMLVGES
| |. ||.. ...|||.||.. |.||||||||.|||.|| .||||||.||| |    ..|||||||...|||..    |...||||  |||..|||.| |
EKRARFYACEIICGLQFLHKKGIIYRDLKLDNVLLDCDGHIKIADFGMCKENMYGEKKASTFCGTPDYIAPEIIKGQKYNHSVDWWSFGVLMYEMLIGQS

PFPGDDEEEVFDSIVNDEVRYPRFLSTEAVAIMRRLLRRNPMRRLGSSQRDAEDIKMQGFF
|| |.||.|.|.||.||.  |||... ||  ....|. |.| .|||. .  . ||.   ||
PFHGEDEDELFWSICNDRPWYPRWITKEAKDCLKKLFERDPEKRLGVQYCPKGDIRQHCFF
Kinase PKN.AA Alpha 536-795 48 1.1e-111 377.36 In-house 1-259 (259) Show / Hide 
Range on Protein: 536-795
Range on HMM: 1-259/259
Sequence Identity: 48% (127 aa)

FRLISVLGRGHFGKVLLTEYKTTGEFFAIKALKKRDVVAREEVESLMCEKRIFEAANSIRHPFLVNLFACFQTEHHVCFVMEYAMGGDLMMHIHN-DVFT
|  ..|||.| ||||.| | |.| | .||| |||  ..    ||  | |||.   | . . |||| .  ||||     |||||  ||||| ||     | 
FNFLMVLGKGSFGKVMLAERKGTDELYAIKILKKDVIIQDDDVECTMVEKRVL--ALPGKPPFLVQMHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGKFK

EPRTVFYSACVVLGLQYLHENKIVYRDLKLDNLLLDQDGFLKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTEPYYTRAVDWWGLGVLIFEMLVGES
||  ||| | .  || .|||  |.|||||||| .|| .|  ||||||.|||.|  .. | ||||||...|||.     | ..||||  ||| .||..|  
EPHAVFYAAEIAIGLFFLHEKGIIYRDLKLDNVMLDAEGHIKIADFGMCKENMWEDQTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMMAGQP

PFPGDDEEEVFDSIVNDEVRYPRFLSTEAVAIMRRLLRRNPMRRLGSSQRDAEDIKMQGFF
|| |.||.|.| .| . .| ||. .| |||.| . .| ..| .|||. . . .||.  .||
PFDGEDEDELFQAIMEHNVSYPKSMSKEAVDICKGFLTKHPNKRLGCGPDGEQDIREHPFF
Kinase PKN.AA SGK 536-795 37 2.1e-103 320.24 In-house 1-283 (283) Show / Hide 
Range on Protein: 536-795
Range on HMM: 1-283/283
Sequence Identity: 37% (109 aa)

FRLISVLGRGHFGKVLLTEYKTT------------------GEFFAIKALKKRDVV-------AREEVESLMCEK-RIFEAANSIRHPFLVNLFACFQTE
|....|.| | ||||.. . | .                  . |.|.| |.|  ..       ...|.   | |.  |    . ..|||.|||   |||.
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVIL---KNMKHPFIVNLHYAFQTK

HHVCFVMEYAMGGDLMMHIH-NDVFTEPRTVFYSACVVLGLQYLHENKIVYRDLKLDNLLLDQDGFLKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVL
    |||.|. ||..  |.     | |.|  || | .|. | |||. .|.||||| .|.||| .| ... ||||||||.   | |.||||||| ||||||
WKLYFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVL

TEPYYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAVAIMRRLLRRNPMRRLGSSQRDAEDIKMQGFF
    . |.|||| || . .||..|  ||   . .. .| | | . . |.. | .|  ..  || ..|  ||| . ||...||   ||
RKQPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLG-TKRDFMEIKNHPFF
Kinase PKN.AA S_TKc 536-795 33 1.7e-95 324.47 SMART 1-231 (231) Show / Hide 
Range on Protein: 536-795
Range on HMM: 1-231/231
Sequence Identity: 33% (90 aa)

FRLISVLGRGHFGKVLLTEYKTTGEFFAIKALKKRDVVAREEVESLMCEKRIFEAANSIRHPFLVNLFACFQTEHHVCFVMEYAMG--GDLMMHIHNDV-
.... ..|.| |||| .   | ||. .||| .|          |... | .| .     .||..|.|. .||. .|...||||. |  |||. .|..   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK----HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

------FTEPRTVFYSACVVLGLQYLHENKIVYRDLKLDNLLLDQDGFLKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTEPYYTR-AVDWWGLGVL
      |.| .. || . ....|.|.|...|..|||| .|.|||.   .||.||||...        .||||||...|||||    |.. ..||| .|..
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI

IFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAVAIMRRLLRRNPMRRLGSSQRDA--EDIKMQGFF
..|||.|. |||  .....|. |.          | ||  ..|..|...| .|..  .  .  .|||.  .|
LYEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase PKN.AA AktR 536-795 37 1.4e-92 313.88 In-house 1-268 (268) Show / Hide 
Range on Protein: 536-795
Range on HMM: 1-268/268
Sequence Identity: 37% (102 aa)

FRLISVLGRGHFGKVLLTEYK-TTGEFFAIKALKKRDVVAREEVESLMCEKRIFEAANSIRHPFLVNLFACFQTEHHVCFVMEYAMGGDLMMHIH-NDVF
|... .||.| |||| | . | ......|.| .|| . . |.  . .  |. |   .. ..|||.|.|. ||||. .  |.|||  ||.|  |.  .  |
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNI--MEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKF

TEPRTVFYSACVVLGLQYLHEN-KIVYRDLKLDNLLLDQDGFLKIADFGLCK-EGMG-YGDRTSTFCGTPEFLAPEVLTE-PYYTRAVDWWGLGVLIFEM
.| .. ||.| ..|.|.|||.. .|.||||| .|.|||.|| .||.|||| | ..|  | ... .|||||| .|||..|.   ....|||| .|..|.||
SEEQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEM

LVGESPFPGDDEEEVFDSIVNDE---VRYPRFLSTEAVAIMR-RLLRRNPMRRLGSSQRDAEDIKMQGFF
..|  ||  .. .. |..| . .   . ||  .| ..  .   .|| .||  |||..  ..|.||.  .|
VTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase PKN.AA Iota 536-795 45 1.2e-90 302.18 In-house 1-271 (271) Show / Hide 
Range on Protein: 536-795
Range on HMM: 1-271/271
Sequence Identity: 45% (124 aa)

FRLISVLGRGHFGKVLLTEYKTTGEFFAIKALKKRDVVAREEVESLMCEKRIFEAANSIRHPFLVNLFACFQTEHHVCFVMEYAMGGDLMMHIHND-VFT
|.|| |.||| . |||. |.| |   .|.| .||  |   |...    || .||.| .  ||||| | .|||||  . ||.|.  ||||| |.       
FELIRVIGRGSYAKVLMVEHKKTRRIYAMKVIKKEMVNDDEDIDWVQTEKHVFEQASN--HPFLVGLHSCFQTESRLFFVIEFVNGGDLMFHMQRQRKLP

EPRTVFYSACVVLGLQYLHENKIVYRDLKLDNLLLDQDGFLKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTEPYYTRAVDWWGLGVLIFEMLVGES
|    |||| ..| |..|||  |.|||||||| |||..| .|. |.|.||||.  || |||||||| ..|||.|    |  .|||| ||||.|||. | |
EEHARFYSAEICLALNFLHERGIIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRS

PFP--G-------DDEEEVFDSIVNDEVRYPRFLSTEAVAIMRRLLRRNPMRRLGSSQRD---AEDIKMQGFF
||   |         |. .|  |.  ..| ||.||  |  ...  | ..|. |||  .      .|||   ||
PFDIVGNMDNPDQNTEDYLFQVILEKQIRIPRSLSVRAAHVLKGFLNKDPKERLGCHPQTNEGFMDIKEHPFF
Kinase PKN.AA Pkinase 536-795 28 1.5e-81 282.03 Pfam 1-293 (293) Show / Hide 
Range on Protein: 536-795
Range on HMM: 1-293/293
Sequence Identity: 28% (86 aa)

FRLISVLGRGHFGKVLLTEYKTTGEFFAIKALKKRDVVAREEVESLMCEKRIFEAANSIRHPFLVNLFACFQTEHHVCFVMEYAMGG----DLMMHIH--
.......|.| ||.| .   | ||. .|.| .|||.    .... .    .  .  ....||. | |. .|... |...||||..||    ||. .|.  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL--SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTW

-NDVF--TEPRTVFYSACVVLGLQYLHENKIVYRDLKLDNLLLDQDGFL----KIADFGLCKE--GMGYGDRTSTFCGTPEFLAPEVLT-EPYYTRAVDW
 . .|  .|    ||   .. ||.|.|...|..||||..|.|.|..| .    ||.||||.|      ..  ..||||||...||||.   .||...||.
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS--MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WGLGVLIFEMLVGESPFPGD------DEEEVFDSIVNDEVRYPRFLS---------------------TEAVAIMRRLLRRNPMRRLGSSQRDAEDIKMQ
|..|....||| |. ||||.      |. .... |   ....... .                      |.  .....|...| .|..     ||.|.  
WSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQILQH

GFF
 .|
PWF
Kinase PKN.AA S_TK_X 796-860 35 2.2e-20 74.97 SMART 1-79 (79) Show / Hide 
Range on Protein: 796-860
Range on HMM: 1-79/79
Sequence Identity: 35% (28 aa)

RNINWDDLLM--RRVTPAFVPKIA----NSEDVSNFDEEFTAEHPVLTPAKDPRELTDEEQE--------HFKDFNYIA
|.|.||.|..  ....| |.|||     . .|.||||.||| | |.|||. .|   .  ..|        .| .|.|..
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase PKN.AA Pkinase_Tyr 536-738 26 7.3e-18 61.12 Pfam 1-218 (270) Show / Hide 
Range on Protein: 536-738
Range on HMM: 1-218/270
Sequence Identity: 26% (60 aa)

FRLISVLGRGHFGKVLLTEYK----TTGEFFAIKALKKRDVVAREE--VESLMCEKRIFEAANSI-RHPFLVNLFACFQ-TEHH--VCFVMEYAMGGDL-
 ... .||.|.||.| . ..|     |.   |.| |  ..    |.   |..| | .|     .. .|| .|.| ..    . .  .. ||||. .||| 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML--KEGAMHEQNCREDFMREAKIMK---QLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLL

-MMHIH---NDVFTEPRTVFYSACVVLGLQYLHENKIVYRDLKLDNLLLDQDGFLKIADFGLCKEGMG---Y-GDRTSTFCGTPEFLAPEVLTEPYYTRA
   . |   .. .| .. . ... .  |..||...... |||   | |.. ... ||.||||..  .    |   |...       .|||.. .  .| .
DYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGKFTTK

VDWWGLGVLIFEMLV-GESP-FPG
 | |  |||..|..  ||.| .||
SDVWSFGVLMWEIFTYGEQPTYPG
Kinase PKN.AA TyrKc 536-789 22 1.1e-16 47.17 SMART 1-280 (280) Show / Hide 
Range on Protein: 536-789
Range on HMM: 1-280/280
Sequence Identity: 22% (66 aa)

FRLISVLGRGHFGKVLLTEYKTTGEFFAIKALKKRDVVAREEVESLMCEKRIFEAANSI--RHPFLVNLFACFQTE-------HHVCFVMEYAMGGDLMM
 .|. .||.|.||.| . ..|   .  |.| ||.        .| .| | ||     ..  .|| .|.|...  ..       . .. ||||. .|||  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMC---KLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

HIHNDV--FTEPRTVFYSACVVLGLQYLHENKIVYRDLKLDNLLLDQDGFLKIADFGLCKEGMGY---GDRTSTFCG----TPEF------LAPEVLTEP
....    .. .  . ..  .  | .|||..... |||   | |.. ..  ||.||||....  .   | ....          .      .|||.. . 
YLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

YYTRAVDWWGLGVLIFEML-VGESPFPG-----DDEEEVFDSIVNDEVRYPRFL---------STEAVAIMRRLLRRNPMRRLGSSQRDAEDI
 .| . | |  ||...|..  |..| ||      . .||.  . . . . .            ..|   ||..  ...|  |   |.   |..
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
Kinase PKN.AA Pkinase_C 815-862 39 5.6e-15 55.96 Pfam 1-46 (46) Show / Hide 
Range on Protein: 815-862
Range on HMM: 1-46/46
Sequence Identity: 39% (19 aa)

KIANSEDVSNFDEEFTAEHPVLTPAKDPRELTDEEQEHFKDFNYIADW
.. . .|.||||.||| |.|..||  |.| .. ..||.| .| | ...
QVKSPTDTSNFDPEFTDEPPMDTP-PDWR-MSSGDQEPFRGFTYVNPD