Gene YANK (Sea Urchin)

YANK

Species: Sea Urchin
Alias: SPU_026079, Spk031, YANK
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: AGC
Family: YANK

Sequence

Name Sequence Type Origin Length Description Download
YANK.AA Protein None 297 None Fasta, JSON
YANK.kin_dom Protein Kinase Domain None 139 None Fasta, JSON

Protein domain

Protein domains of YANK.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase YANK.AA YANK 31-169 71 1.4e-111 377.02 In-house 123-261 (261) Show / Hide 
Range on Protein: 31-169
Range on HMM: 123-261/261
Sequence Identity: 71% (100 aa)

RDIKPDNILLDEDGHVHITDFNIATIVKANVYGTSMSGTKPYMAPEIFQTATDDCKGYSYPVDWWSLGVCAYEMLRTKRPYDIHANSSIADIQHLFSTNT
||||||||||||.||||||||||||..|.|...||||||||||||||||...|.||||||||||||||||||||||..|||.||.|..|..|.|.||||.
RDIKPDNILLDEHGHVHITDFNIATMLKDNQRATSMSGTKPYMAPEIFQCYMDECKGYSYPVDWWSLGVCAYEMLRGWRPYHIHSNTPIEEIYHMFSTNS

VHYPSTWNPSLTDLIRQLLSVDPRERISDLESLSKHPFM
|||||.|.....||.|.||.|||..|||.|....|||.|
VHYPSHWCQEMVDLLRKLLTVDPEHRISSLQDIQKHPYM
Kinase YANK.AA AGC 31-169 22 3.9e-60 153.15 In-house 178-395 (395) Show / Hide 
Range on Protein: 31-169
Range on HMM: 178-395/395
Sequence Identity: 22% (51 aa)

RD-IKPDNILLDEDGHVHITDFNIATIVKAN---------------------------------------------------VYGTSMSG--TKPYMAPE
|| .||.|||||||||...|||  ..... .                                                   .  ... |  |  |||||
RDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPE

IFQTATDDCKGYSYPVDWWS--LGVCAYEMLRTKRPYDIH-------------ANSSIADIQHLFSTNTVHYP----------STWNPSLTDLIRQLLSV
|.         |....||||  ||.. ||||  . |.  .                    . ..|... |..|          . . | . |||..|| .
IL---------YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCK

DPRERIS---------DLESLSKHPFM
||..|.          . | . .||. 
DPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase YANK.AA Ciliate-E2 31-169 25 3e-34 114.96 In-house 185-365 (365) Show / Hide 
Range on Protein: 31-169
Range on HMM: 185-365/365
Sequence Identity: 25% (51 aa)

RDIKPDNILLDEDGHVHITDFNIATIVKAN------------------VYGTSM--------------SGTKPYMAPEIFQTATDD----CKGYSYPVDW
|||||.|||.     . |.|| ...... .                   ..|.                || .||||||..   .|     |||.| .|.
RDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDI

WSLGVCAYEMLRTKRPYDIHANSSIADIQHLFSTNTVHYP------------------STWNPSLTDLIRQ----LLSVDPRERISDLESLSKHPFM
|||||. ||||  |.|.           |     . . .|                    | ..  |||..    .| .|| .||.. | . .||..
WSLGVILYEMLFGKPPF-----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase YANK.AA Ciliate-E2-Unclassified 31-169 25 1.1e-32 110.68 In-house 168-352 (352) Show / Hide 
Range on Protein: 31-169
Range on HMM: 168-352/352
Sequence Identity: 25% (49 aa)

RDIKPDNILLDEDG---HVHITDFNIATIVKANVY----------------GTSMSGTKPYM----APEIFQTATDDCKGYS----YPVDWWSLGVCAYE
|||||.|||.|..|   .. |.|| |.   . |..                 ....||  ||    |||..|      ..|.    | .|.|||||..||
RDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQG-----QNYDHSKAYKCDIWSLGVILYE

MLRTKRPY-DIHANS---------------SIADIQHLFSTNTVHYPS-----TWNPSLTDLIR----QLLSVDPRERISDLESLSKHPFM
||  ..|. |   ..                . ....   ..  ..|      .|.|.  |.|.    ..| ..| .|| ..| . .||..
MLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRI-TFEQILNHPWF
Kinase YANK.AA Pkinase 31-169 26 1.9e-32 115.85 Pfam 132-293 (293) Show / Hide 
Range on Protein: 31-169
Range on HMM: 132-293/293
Sequence Identity: 26% (45 aa)

RDIKPDNILLDEDGHV----HITDFNIATI--VKANVYGTSMSGTKPYMAPEIFQTATDDCKGYSYPVDWWSLGVCAYEMLRTKRPYDIHA---NSSIAD
||.||.|||.|..||.    .|.|| .|       |.  |.  || .|||||. .    ....|...||.||.|.  ||||  . |.. ..    . . .
RDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR----GGQYYGPKVDMWSCGCILYEMLCGRPPFP-GHCWHDN-HDQ

IQHLFSTNTVHYPSTWN-----------------------PSLTDLIRQLLSVDPRERISDLESLSKHPFM
.| .. .    ... |                        ... |.|. .| .|| .|..  | . .||..
MQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-AEQILQHPWF
Kinase YANK.AA Ciliate-E2b 31-169 29 2.2e-29 86.55 In-house 126-272 (272) Show / Hide 
Range on Protein: 31-169
Range on HMM: 126-272/272
Sequence Identity: 29% (44 aa)

RDIKPDNILLDEDGHVHITDFNIATIVKANVY----GTSMSGTKPYMAPEIFQTATDDCKGYSYPVDWWSLGVCAYEMLRTKRPYDIHANSSIADIQHLF
||||| ||..|..|.. . |. .| . . .       ... ||  |||||| |      |||.| || ||.|.| ||..  . |..  .   .   |   
RDIKPENIMVDHKGYMKLIDMGTAKHMYKKNEQMTRTFTIIGTPHYMAPEIIQSLQPGGKGYTYKVDIWSVGICLYEFMCGYVPWAEDVQDPYEIYQEII

ST-NTVHYPSTWNPSLT--DLIRQLLSVDPRERI-SDLESLSKHPFM
.  . . .||     .   .|. |.|.  |  |     ..|  ||. 
KKYDEIQFPSYCKDKMADKKLMLQCLQKMPEVRLGGSYSWLKSHPWF
Kinase YANK.AA GRK 31-169 31 2e-27 83.25 In-house 130-272 (272) Show / Hide 
Range on Protein: 31-169
Range on HMM: 130-272/272
Sequence Identity: 31% (47 aa)

RDIKPDNILLDEDGHVHITDFNIATIVKANV-YGTSMSGTKPYMAPEIFQTATDDCKGYSYPVDWWSLGVCAYEMLRTKRPYDIHANSSIA-DIQHLFST
|| || |||||..||| | |   |  .. .        ||  |||||. |  .     |....||||||.  |||.. . |   |       .. ..  .
RDLKPENILLDDHGHVRISDLGLACEIPEGQPMIHGRVGTHGYMAPEVLQNER----AYDFSPDWWSLGCMIYEMIEGHSPFRQHKEKVKREEVDRRVKE

NTVHYPSTWNPSLTDLIRQLLSVDPRERISDLES------LSKHPFM
 .| ||.  .. . |. ..||  || .|    .       . .||| 
DPVKYPDKFSEEAKDICEMLLQKDPEQRLGCRGGTCGAQEVKEHPFF
Kinase YANK.AA MSK 31-156 32 1.4e-26 86.9 In-house 125-265 (277) Show / Hide 
Range on Protein: 31-156
Range on HMM: 125-265/277
Sequence Identity: 32% (46 aa)

RDIKPDNILLDED---GHVHITDFNIATIVKAN--VYGTSMSGTKPYMAPEIFQTATDDCKGYSYPVDWWSLGVCAYEMLRTKRPYD--IHANS----SI
||.|| |||.|..   ||| ..||  | .  ..      |  .|  |||||. ...     ||.  .|||||||  |.||  ..|.    .  .    | 
RDLKPENILFDDEEDNGHVKLIDFGFARLFPQDEEWRMKSPCFTLHYMAPEMLRRGYAQDGGYDEACDWWSLGVILYTMLTGQVPFQQNEDDRQHSCNSH

ADIQHLFSTNTVHYP----STWNPSLTDLIRQLLSVDPRER
..|     . .. .|    ..  |   |||..|| .||  |
HEIMKRICKGEFSFPGMAWQNMSPDAKDLIQWLLTKDPKKR
Kinase YANK.AA STE 31-169 26 1.6e-26 90.69 In-house 176-359 (359) Show / Hide 
Range on Protein: 31-169
Range on HMM: 176-359/359
Sequence Identity: 26% (52 aa)

RDIKPDNILLDEDGHVHITDFNIATIVKANVYGT-----------------SMSGTKPYMAPEIFQTATDD-CKGYSYPVDWWSLGVCAYEMLRTKRPY-
|||||.||||     | ..|| .....  .. .                  .. ||  .||||. |  . .  |||.. .| |||| .. ||.  | |. 
RDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWH

DIHAN---SSIA-----------------DIQHLFS--------------TNTVHYPSTWNPSLTDLIRQLLSVDPRERISDLESLSK--HPFM
| |       |.                 ..  | .              | |  ||. | |.. | |.. |  ||..| .  . | |  ||| 
DMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGT-T--YPHKWSPEFKDFINKCLQKDPNKRPTASQ-LLKSEHPFI
Kinase YANK.AA RSK 31-169 32 2.2e-25 89.93 In-house 128-278 (278) Show / Hide 
Range on Protein: 31-169
Range on HMM: 128-278/278
Sequence Identity: 32% (49 aa)

RDIKPDNILLDE---DGHVHITDFNIATIVKANVYGTSMS--GTKPYMAPEIFQTATDDCKGYSYPVDWWSLGVCAYEMLRTKRPYDIHANS-SIADIQH
||.||.|||.|.   .||. .|||  . . ...  .  |.  .|  |||||.  .|    .|..  .|||||||  ||||  ..|.    |. . ..|  
RDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRAN-QQGGHDKACDWWSLGVLMYEMLTGCPPFQG-PNDNNRKEIMK

LFSTNT--VHYP--STWNPSLTDLIRQLLSVDPRERIS----DLESLSKHPFM
   ...  .  |  ..  .   ||||..| .||  |..    |.| . .||..
RIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase YANK.AA AktR 31-169 35 7.9e-25 88.82 In-house 126-268 (268) Show / Hide 
Range on Protein: 31-169
Range on HMM: 126-268/268
Sequence Identity: 35% (53 aa)

RDIKPDNILLDEDGHVHITDFNIAT--IVK-ANVYGTSMSGTKPYMAPEIFQTATDDCKGYSYPVDWWSLGVCAYEMLRTKRPYDIHANSSIADIQHLFS
||.||.|||||||||| ||||  .   ...  .   .|  ||  |||||. .      ||. ..||||..|.  |||.    | . | |  .  .  ...
RDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKK----KGHNKSVDWWAFGIFIYEMVTGCPPFY-HKNQNQMFQKIKIK

T-NTVHYPSTWNPSLTDLIR-QLLSVDPRERIS----DLESLSKHPFM
. | . |||   . . |||  .||  .|..|.     . | . .||. 
QQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
S_TKc YANK.AA S_TKc 1-169 20 3e-12 2.77 SMART 17-231 (231) Show / Hide 
Range on Protein: 1-169
Range on HMM: 17-231/231
Sequence Identity: 20% (51 aa)

MAYDVA------------------GIMSRTHAESAVGHSCTYS------------G--------LEQP--------------------------------
 ....                    |... | .  |    ..             |        ...                                 
KCRHKKTGRIVAIKIIKEHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPEHARFYMYQICCALEYCHSHGI

--RDIKPDNILLDEDGHVHITDFNIATIVKANVYGTSMSGTKPYMAPEIFQTATDDCKGYSY-PVDWWSLGVCAYEMLRTKRPYDIHANSSIADIQHLFS
  ||.||.||||||  |. |.|| .|...      |.. ||  |||||..        ||.. ..||||.|.. ||||  . |..      .. . ..  
IHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL--------GYGKCKCDWWSCGCILYEMLCGYPPFP-----QMQMMFKKIG

TNTVHYPSTWNPSLTDLIRQLLSVDPRERISDLESLS------KHPFM
           |.. |.||..| .||..|..  | |       .||..
----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF