Gene RIO2 (Sea Urchin)

RIO2

Species: Sea Urchin
Alias: RIO2, Spk051, SPU_008717
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: Atypical
Family: RIO
Subfamily: RIO2

Sequence

Name Sequence Type Origin Length Description Download
RIO2.AA Protein None 512 None Fasta, JSON

Protein domain

Protein domains of RIO2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase RIO2.AA RIO2 69-304 56 1.5e-159 536.33 In-house 1-260 (260) Show / Hide 
Range on Protein: 69-304
Range on HMM: 1-260/260
Sequence Identity: 56% (146 aa)

YRLTYPGYDYLALKALVARDAVASVGNQIGVGKESDIYIVANDNDEQLALKLHRLGRTSFRKLKEKRDYLGKRKSASWLYLSRLAAMKEFAFMKALYDHG
||||  |||||||| | .|  | |||||.|||||||||...| | .| ..|.||||||||. .| .|||. .| ..||.|||||.||||..||..||  .
YRLTNAGYDYLALKTLSSRQVVYSVGNQMGVGKESDIYKCSNENGNQFIMKFHRLGRTSFHNIKNNRDYHKHRHQYSWMYLSRLSAMKEYQFMDMLYKRN

FPVPTPIDFSRHCVVMELMNAYPLNQVHTLDDPASVYDDLMNLIVRLANHGLIHGDFNEFNLMLDDQDQ------ITLIDFPQMVSTSHENAEWYFNRDV
|||| ||| .|| ||||| | ||. | |  |.|..|||..| .|||||||||||.||||||||.||.|.      ...|||||||||.| ||.||| |||
FPVPKPIDYNRHIVVMELINGYPMCQIHHHDNPPYVYDQCMCFIVRLANHGLIHCDFNEFNLMIDDNDHDENDCGFIMIDFPQMVSTQHQNAQWYFDRDV

QCVVDFFNRRFNYKSELYP------------------KFSDITCEKTLDVDVAASGFSKE
 |. .|| .|||| ....|                   | ||  . |||. | ||||.|.
DCIHRFFMKRFNYEPKPFPSMLDTEGFGDGYKYAYPDFFRDIQRTDTLDEEVQASGFNKK
Kinase RIO2.AA RIO 69-297 38 8e-119 401.05 In-house 1-276 (276) Show / Hide 
Range on Protein: 69-297
Range on HMM: 1-276/276
Sequence Identity: 38% (106 aa)

YRLTYPGYDYLALKALVARDAVASVGNQIGVGKESDIYIVANDNDE-----------QLALKLHRLGRTSFRKLKEKRD---YLGKRKS-ASWLYLSRLA
|..|  .|...... .| |  | ||||.||||||||||...| | |           . |.|.||.|||||. .| .||   |. .| . ..|.|..||.
YEQTNDPYTRMIMYKMVNRGMVESVGNCIGVGKESDIYHCSNENGEDEKEDSKVIPTECAIKIHRTGRTSFKDRKKYRDGEFYFKHRHCKHNWRYMHRLW

AMKEFAFMKALYDHGFPVPTPIDFSRHCVVMELMNA-------YPLNQVHTLDDPASVYDDLMNLIVRLANHG-LIHGDFNEFNLMLDDQDQ------IT
|.||...||.||  |||.|.||| .|| .|||. |        ||. | | ......||...| ...||..|. |.|.||||||.|..| .       ..
AEKEMRNMKRLYQSGFPCPEPIDYKRHVLVMEFINHDQMPAPKYPMCQIHEHENMKHVYHQCMCYMRRLYQHCRLVHCDFNEFNMMWHDGKHDENDCGFY

LIDFPQMVSTSHENAEWYFNRDVQCVVDFFNRRFNYKSELYPKFSDIT------------------CEKTLDVDVA
.|||||||...| .|.||| ||. || .|| .||.| ... . . |.                    . |||... 
MIDFPQMVEHDHPHALWYFRRDCKCVNMFFMKRFVYEPFPEREMFDFVGFGDGYKYAYPDFKRDVKRTDTLDHENM
Kinase RIO2.AA RIO1 104-283 27 7.4e-80 249.51 Pfam 1-200 (200) Show / Hide 
Range on Protein: 104-283
Range on HMM: 1-200/200
Sequence Identity: 27% (55 aa)

DIYIVAN-DNDE-QLALKLHRLGRTSFRKLKEKRDYLGK----RKSASWLYLSRLAAMKEFAFMKALYDHGFPVPTPIDFSRHCVVMELMN---AYPLNQ
..| ..   ... ..|.|..|.|.|.|.| |..|||       .   .|.|..|..|.|||...|..| .|.|.| |||. ||..|||.      .|. .
NVYHAYSMEDGKDECAVKIYRTGTTCFKKMKRYRDYDFRFRHRYHHHNWRYMVRMWAEKEFRNLKRMYEAGVPCPKPIDWNRHVLVMEFIGDKDGWPAPR

VHTLD--------DPASVYDDLMN--LIVRLANHGLIHGDFNEFNLMLDDQDQITLIDFPQMVSTSHENAEWYFNRDVQCVVDFFNRRFNYK-SELYPKF
.. ..        .....||...   ........||.|||..|.|....| . ...||.||.|...|..|.... ||......|| |.. .. .. ....
LKDVEMELELSEEEAEEIYDEIIREYMRRMYQECGLVHGDLSEYNILVHDDGKPWIIDWPQAVEHDHPHALEFLERDCRNIINFFRRKGVDERVMDFREI
RIO RIO2.AA RIO 62-285 20 9.9e-58 199.03 SMART 1-253 (253) Show / Hide 
Range on Protein: 62-285
Range on HMM: 1-253/253
Sequence Identity: 20% (53 aa)

EHGKVSGYRLTYPGYDYLALKALVARDAVASVG--NQIGVGKESDIYIV----ANDNDEQLALKLHRLGRTSFRKLKEKRDYLGKRK----SASWLYLSR
.  . ..|.... ......|...|.|. .....  ..|..|||...| .    . .|..  | | .|...|.|.. .. ...  . |     ..|....|
DKEDYATYEEVFDPRTRMTLYKMVNRGYIEEINNHGCISTGKEANVYHAMGGDFDKNGNECAVKIYRTSTTEFKRMWRYIQGDFRFKHGYHHINWRKMVR

LAAMKEFAFMKALYDHGFPVPTPIDFSRHCVVMELMNA----YPLNQVHTLDDPA-----SVYDDLMNLIVRLANHG-LIHGDFNEFNLMLD-----DQD
|.| ||| ... .| .|.|.|.||...|| .|||.  .    .|   .......       .|...|  ...... . |.|.|..|.|....     . .
LWAEKEFRNLQRMYEAGVPCPKPIAWRRHVLVMEFIGDDGWPAPRLKDVEWEEWEMDFKWEYYWQIMEYMRKMYHECHLVHADLSEYNMLYHDLEDENDC

QITLIDFPQMVSTSHENAEWYFNRDVQCVVDFFNRRFNYKS----ELYPKFSD
 . .||..| |...|. .. .. ||.... .|| |.  ..     |.. .. .
KVWIIDWSQSVECDHPMWLEFLERDIWNIINFFRRKGVDCDDIYREIFERITG
Rio2_N RIO2.AA Rio2_N 21-87 56 4.3e-35 120.78 Pfam 16-84 (84) Show / Hide 
Range on Protein: 21-87
Range on HMM: 16-84/84
Sequence Identity: 56% (39 aa)

EMGMKNHEIVPSNLVASIANLR-HGGCHKVLKELVRNKLIAW-EHGKVSGYRLTYPGYDYLALKALVAR
||||.|||.||..|...|..|| |||||..|..|...|||.  .. |  |||||| |||||||...| |
EMGMRNHEWVPTELIHQISRLRSHGGCHYRLSRLCKHKLISHVQNKKYDGYRLTYGGYDYLALHTFVKR
Kinase RIO2.AA Ciliate-C3 215-243 37 0.000108 13.18 In-house 112-140 (140) Show / Hide 
Range on Protein: 215-243
Range on HMM: 112-140/140
Sequence Identity: 37% (11 aa)

LANHGLIHGDFNEFNLMLDDQDQITLIDF
|  | ..|||    |...  .|.| .|||
LHEHNIVHGDIKFSNILINSKDEIKIIDF
Kinase RIO2.AA APH 114-177 19 0.000386 15.0 Pfam 1-63 (248) Show / Hide 
Range on Protein: 114-177
Range on HMM: 1-63/248
Sequence Identity: 19% (13 aa)

EQLALKLHRLGRTSFRKLKEKR-DYLGKRKSASWLYLSRLAAMKEFAFMKALYDHGF--PVPTPIDF
.  ..   . .|| .|   . | .|. .| ...    .. .. .|......| .||.  ||| ....
WWRPISGGWSNRTYYRTTDD-RPRYVLRRYPPP---WWAEELHREHRWLRHLAAHGIPVPVPRVLWG
Kinase RIO2.AA APH 204-243 25 0.001823 12.7 Pfam 159-199 (248) Show / Hide 
Range on Protein: 204-243
Range on HMM: 159-199/248
Sequence Identity: 25% (11 aa)

VYDDLMNLIVRLANHGLIHGDFNEFNLMLD---DQDQI-TLIDF
....| ..       ...||||.  |.|.|   |....  .||.
LWAWLEAHWP---PPCWCHGDFHPGNVMWDPRPDGGRVTGVIDW