Gene DAPK (Sea Urchin)
DAPK
Sequence
Protein domains of DAPK.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | DAPK.AA | DAPK | 13-201 | 64 | 1.3e-177 | 516.92 | In-house | 1-192 (264) | Show / Hide |
Range on Protein: 13-201 Range on HMM: 1-192/264 Sequence Identity: 64% (124 aa) YQIGEDIGSGQFSEVKKVTEKSTGKDYAGKFIRKRRSTASRRGVKREDIVREVSILEELS-HDNIISLHDAFELQKEVVLILELVTGGELFHYLAEEDHV |..||.||||||..|||..||||||.||.|||.|||.|||||||.||||.||||||.|.. |.|||.|||..|....||||||||.|||||..|.|.... YDMGEEIGSGQFAVVKKCREKSTGKEYAAKFIKKRRYTASRRGVSREDIEREVSILREIRGHPNIITLHDVYENKTDVVLILELVSGGELFDFLCEKECL NEEVAAQFVKKILEALKHMHDRNICHLDLKPENIMLLNRNTQN--IMLIDFGLSRRIKPGEDIRDIMGTAEFVAPEIINFEPLSLNTDMWPV |||.|.||.|.||....|||...|||.||||||||||.||..| |..|||||..||.||.....|.||.|||||||.|.|||.|.|||| . NEEEATQFIKQILDGVHHMHSKHICHFDLKPENIMLLDRNVPNPRIKIIDFGLAHRIEPGNEFKNIFGTPEFVAPEIVNYEPLGLETDMWSI |
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Kinase | DAPK.AA | DAPK | 15-201 | 58 | 2.5e-163 | 453.9 | In-house | 1-192 (264) | Show / Hide |
Range on Protein: 15-201 Range on HMM: 1-192/264 Sequence Identity: 58% (112 aa) IGEDIGSGQFSEVKKVTEKSTGKDYAGKFIRKRRSTASRRGVKREDIVREVSILEELS-HDNIISLHDAFELQKEVVLILELVTGGELFHYLAE--EDHV .||..|.|||..|.|...|||||.||.|||.|||...|||||.||.|..|..||||.. |.|.|.||...|....|.||||.|.|||||.|..| |... MGEELGRGQFAVVRKCRHKSTGKHYAAKFIKKRRRGQSRRGVCREEIEHEIAILEECRGHPNVINLHEVYETRTDVILILEYVSGGELFDYCCEDREECL NEEVAAQFVKKILEALKHMHDRNICHLDLKPENIMLLNRNTQN--IMLIDFGLSRRIKPGEDIRDIMGTAEFVAPEIINFEPLSLNTDMWPV .||.|..|.|.|||.....|.||||||||||.||||..||... |..|||||||.|..||..||||||.|.|||||.|.|||||.|||| . CEEDATRFMKQILEGVHYLHSRNICHLDLKPQNIMLTDRNIPQGDIKIIDFGLSRKICNGEEFRDIMGTPEYVAPEIVNYEPLSLATDMWSI |
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Kinase | DAPK.AA | MLCK | 13-199 | 44 | 5.5e-107 | 282.87 | In-house | 1-183 (257) | Show / Hide |
Range on Protein: 13-199 Range on HMM: 1-183/257 Sequence Identity: 44% (84 aa) YQIGEDIGSGQFSEVKKVTEKSTGKDYAGKFIRKRRSTASRRGVKREDIVREVSILEELSHDNIISLHDAFELQKEVVLILELVTGGELFHYLA-EEDHV |||.|..| | |. | ...|||||| .| |||. |.....|....|..|. .| | |.| .||||| ..|.|.|.|...||||| . |..| YQIHEELGRGKFGIVHRCIEKSTGKTWAAKFIKC------RKPKDKENVKNEIEIMNQLHHPNLIQCHDAFETKNEMVMIMEYISGGELFERIVDEDFHL NEEVAAQFVKKILEALKHMHDRNICHLDLKPENIMLLNRNTQNIMLIDFGLSRRIKPGED-IRDIMGTAEFVAPEIINFEPLSLNTDMW .|.. . ... |.|...|||..||.||||||||||. .|. .| .||||| |...|.|. .. || ||||||..|..|... |||| TEREVIHYMRQICEGVHHMHWQNIVHLDLKPENIMCQTRTSHQIKIIDFGLARKYDPDEKKVKVMFGTPEFVAPEVVNYDPVGFQTDMW |
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Kinase | DAPK.AA | CAMK | 18-199 | 21 | 6.3e-74 | 237.41 | In-house | 1-318 (425) | Show / Hide |
Range on Protein: 18-199 Range on HMM: 1-318/425 Sequence Identity: 21% (68 aa) DIGSGQFSEVKKVTEKSTG------------KDYAGKFIRKRRSTAS----------------------RRGVKREDIVREVSILEELS-------HDNI .|.|.|..||....|.|. . .| |.| |.. . . ||...|. . ||..|. |. | || TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI ISLHDAFEL-------------------QKEVVLIL---ELVTGGEL----FHYLAEE---------------DHVNEEVAAQFVKKILEALKHMHDRNI |.|....| .|...... |...|||| | |. | ...|. |..... |..|....|..|| IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI CHLDLKPENIMLLNRNT---------------QNIMLIDFGLSRRIKP------------------------GEDIRDIMGTAEFVA-PEIINF------ .|.|||||||.| ..|. || .||||......| |. .. || |..| ||..| VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM --------EPLSLNTDMW .. . .||| QNATDEEKPYYGPKCDMW |
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Kinase | DAPK.AA | DRAK | 16-201 | 38 | 9.6e-71 | 218.91 | In-house | 2-187 (259) | Show / Hide |
Range on Protein: 16-201 Range on HMM: 2-187/259 Sequence Identity: 38% (73 aa) GEDIGSGQFSEVKKVTEKSTGKDYAGKFIRKRRSTASRRGVKREDIVREVSILEE-LSHDNIISLHDAFELQKEVVLILELVTGGELFH--YLAEEDHVN . . | |.| | | .|.||...| ||..||| . |..|..|. .|. . ...| ||. .| . |..|.||. .|||.|. . .|. . AKERGRGKFAVVRKCIHKNTGQHFAAKFMKKRRRGQDC----RMEILHEIAVLMLCQDCPWVINLHEVYETRSEMILVLEYAAGGEIFQYCVADKEECFC EEVAAQFVKKILEALKHMHDRNICHLDLKPENIMLL-NRNTQNIMLIDFGLSRRIKPGEDIRDIMGTAEFVAPEIINFEPLSLNTDMWPV |. . . ...|||... .|.||| |||||| ||.| . | ..|||.|| |. ||..|.|||| ..||||| |..|... |||| . EKDVQRCMRQILEGVHYLHQRNIVHLDLKPQNILLTSEYPEDDIKICDFGMSRYICNGEEVREIMGTPDYVAPEILNYDPITMATDMWSI |
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Kinase | DAPK.AA | Trio | 13-201 | 35 | 6.2e-68 | 172.92 | In-house | 1-186 (258) | Show / Hide |
Range on Protein: 13-201 Range on HMM: 1-186/258 Sequence Identity: 35% (69 aa) YQIGEDIGSGQFSEVKKVTEKSTGKDYAGKFIRKRRSTASRRGVKREDIVREVSILEELSHDNIISLHDAFELQKEVVLILELVTGGELFHYLAEEDHVN | . | || | || |.....|.||.. | ||| . | ..| .| ..| |.|. ..||||..| . .||||| ..||| .|.. . . YTFQEEIGRGRFSVVRRCWHKATGRTCAAKFI-------PYRMMDKEQVYHEYEMLQHLQHPCVCSLHDTYETPRHYILILELCDDGELLCCLMRWGSYC EEVAAQFVKKILEALKHMHDRNICHLDLKPENIMLLNRNT--QNIMLIDFGLSRRIKPG--EDIRDIMGTAEFVAPEIINFEPLSLNTDMWPV |. . .. .|||. | | |||.||||.|. .| . | ..||| . |. | . |. ||.|||||. .| |. || |.. ESEVKTYMWQMLEAVHYLHNCHILHLDIKPENMMMWHYNAGRPQIKICDFGDAQQLWPHKVEPQHHQYGNPEFMAPEIIQGNPVSYGTDIWSI |
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Kinase | DAPK.AA | CAMK1 | 13-199 | 35 | 8.5e-66 | 190.23 | In-house | 1-200 (276) | Show / Hide |
Range on Protein: 13-199 Range on HMM: 1-200/276 Sequence Identity: 35% (72 aa) YQIGEDIGSGQFSEVKKVTEKST---GKDYAGKFIR-KRRSTASRRGVKREDIVREVSILE---ELSHDNIISLHDAFELQKEVVLILELVTGGELFHYL |..|. ||.| ||||...|.|.| ||.|| | | |. ... |.| . .|..|. ...| |||.... .| ... |..|||||||||. YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQ-KQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRI AEEDHVNEEVAAQFVKKILEALKHMHDRNICHLDLKPENIMLLNR-NTQNIM--LIDFGLSRRIKPGED-IRDIMGTAEFVAPEIINF---EPLSLNTDM | .. .|. |. .|.||.|...||...|.| ||||||. . . . |. ..|||||......|. . || ..||||... .| . || VEKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDM W | W |
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Kinase | DAPK.AA | Ciliate-E2a | 13-188 | 33 | 1.8e-57 | 167.74 | In-house | 1-183 (275) | Show / Hide |
Range on Protein: 13-188 Range on HMM: 1-183/275 Sequence Identity: 33% (62 aa) YQIGEDIGSGQFSEVKKVTEKSTGKDYAGKFIRKRRSTASRRGVKREDIVREVSILEELSHDNIISLHDAFELQKEVVLILELVTGGELFHYLAEEDHVN | . ||.|.| |.... | |||..| | . | . . . ..| . .|..|. .|.|.||| |.. .| . |..|.. ||||.... . . . YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQ--KKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFF EE--VAAQFVKKIL-EALKHMHDRNICHLDLKPENIMLL--NRNT---QNIMLIDFGLSRRIKPGED--IRDIMGTAEFVAPEIIN || ..... ...| ..| .|| ||| | |||||||.. . | ..|..|||||...|.. | . . ||. .||||..| EEIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLN |
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Kinase | DAPK.AA | Pkinase | 13-199 | 30 | 9.2e-56 | 196.36 | Pfam | 1-196 (293) | Show / Hide |
Range on Protein: 13-199 Range on HMM: 1-196/293 Sequence Identity: 30% (63 aa) YQIGEDIGSGQFSEVKKVTEKSTGKDYAGKFIRKRRSTASR------RGVKREDIVREVSILEELSHDNIISLHDAFELQKEVVLILELVTGG----ELF |.||. |||| |..|.| ..|.||| .| | |.||. . . .|..|. .|.|.||. |.|.|| ... ...|.. || .|| YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL--------SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLF HYLA--EEDHV--NEEVAAQFVKKILEALKHMHDRNICHLDLKPENIMLLNRNTQN---IMLIDFGLSRR--IKPGEDIRDIMGTAEFVAPEIIN-FEPL .|. .. . |... ... ||..|...|...|.| |||||||.. .| .. . ..||||.. . ... .. || ...|||.|. .. DYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYY SLNTDMW . ||| GPKVDMW |
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Kinase | DAPK.AA | CAMKL | 13-191 | 30 | 2e-51 | 162.27 | In-house | 1-211 (297) | Show / Hide |
Range on Protein: 13-191 Range on HMM: 1-211/297 Sequence Identity: 30% (65 aa) YQIGEDIGSGQFSEVKKVTE-KSTGKDYAGKFIRKRRST--ASRRGV------KRED-IVREVSILEELS---HDNIISLHDAF-------ELQKEVVLI |.||. .| | |..|| | . ||. .| |.| |.. . . .. . | ||..|.. |. | |||.|.. . | |...|. YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIET-KKIYLV LELVTGGE--LFHYLAEEDH----VNEEVAAQFVKKILEALKHMHDRNICHLDLKPENIMLLNRNTQNIMLIDFGLSRRIKP-----GEDIRDIMGTAEF .|.. ||| ||.|. .. | |. | .. . |..|....|...|.| |.|||||.| ... .|| .||||.| ..| |. . |. .. MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY VAPEIINF--EP ||||.. .| MAPEIFQGNNKP |
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Kinase | DAPK.AA | S_TKc | 13-274 | 24 | 1.1e-50 | 175.66 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 13-274 Range on HMM: 1-231/231 Sequence Identity: 24% (69 aa) YQIGEDIGSGQFSEVKKVTEKSTGKDYAGKFIRKRRSTASRRGVKREDIVREVSILEELSHDNIISLHDAFELQKEVVLILELVTG--GELFHYLAEEDH |.|.. ||.| |..|.|...|.||. .| | |. |.| ||..||.. |.||. |.|.|. ... ...|.. | |.||.|. . . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR ------VNEEVAAQFVKKILEALKHMHDRNICHLDLKPENIMLLNRNTQNIMLIDFGLSRRIKPGEDIRDIMGTAEFVAPEIINFEPLSL-NTDMWPV-- .| .|. ... |..||...|...|.| |||||||.| . .|...||||.|.. . . || ...|||.. . . |.| . HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC ----FISSRLPNIQLIQLSRSQVIQLVCVFISPKMGHRREQLALRKMSKALRSDWEHGETALHLAAGYGHVDILEYL ... . | ....... . |. ..| |. | |. || . .. .. . ... ILYEMLCGYPPFP-----QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | DAPK.AA | RSK | 15-188 | 30 | 3.8e-45 | 156.29 | In-house | 1-181 (278) | Show / Hide |
Range on Protein: 15-188 Range on HMM: 1-181/278 Sequence Identity: 30% (56 aa) IGED--IGSGQFSEVKKVTEKSTGKDYAGKFIRKRRSTASRRGVKREDIVREVSILEELS-HDNIISLHDAFELQKEVVLILELVTGGELFHYLAEEDH- . .. .| | .. ..|.| . ||. || | ..|. .. . .. .|..|||. | .|..||.||. .... ||.|.. ||||| | .| | LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKD--TRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHF --VNEEVAAQFVKKILEALKHMHDRNICHLDLKPENIMLLNRNT-QNIMLIDFGLSRR--IKPGEDIRDIMGTAEFVAPEIIN |. |.. .| |..|.|.. | | |||||||.. .... |.|.|||... .. .. .|.|..|||... GCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLK |
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Kinase | DAPK.AA | TyrKc | 13-271 | 22 | 3.9e-11 | -42.69 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 13-271 Range on HMM: 1-280/280 Sequence Identity: 22% (68 aa) YQIGEDIGSGQFSEVKKVTEKSTGKDYAGKFIRKRRSTASRRGVKREDIVREVSILEEL--SHDNIISLHDAFELQ-------KEVVLILELVTGGELFH . |. .|.|.| || | | | . | | ... |||. || .|. .| .|.||. |. . | . . ...|.. .| | . ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD YLAEEDH-VNEEVAAQFVKKILEALKHMHDRNICHLDLKPENIMLLNRNTQNIMLIDFGLSRRIKPG------EDIRDIMG--TAEFV------APEIIN || . . .. . .| | . . |..|. | || |... ... . |||||| |. . .| . .. . .. ||| || YLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECIN FEPLSLNTD-------MWPVFISSRLPNIQLIQ--LSRSQVIQLVCVFISPKMGHRREQLAL--------------RKMSKALRSDWEHGETALHLAAGY . . .| || .| | || .| ..||..| | |.|..| . . |.. . | | | . YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYV------KQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI---- GHVDIL .... --HECF |
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Kinase | DAPK.AA | Ank | 386-418 | 48 | 7.9e-11 | 43.32 | Pfam | 1-33 (33) | Show / Hide |
Range on Protein: 386-418 Range on HMM: 1-33/33 Sequence Identity: 48% (16 aa) HGITPLHHAVRRQHYDIVKYLVDSNCDVNLQDK .| |||| |.|. |...||.|.. ..|||.||. DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD |
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Kinase | DAPK.AA | Ank | 320-352 | 39 | 3.6e-10 | 40.95 | Pfam | 1-33 (33) | Show / Hide |
Range on Protein: 320-352 Range on HMM: 1-33/33 Sequence Identity: 39% (13 aa) DGETPLHIAAWHGYTSIVQTLCKAGATLDLKNK ||.||||.|. .|.|..|. | ..|| ...... DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD |
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Kinase | DAPK.AA | Ank | 254-286 | 36 | 1.3e-09 | 38.88 | Pfam | 1-33 (33) | Show / Hide |
Range on Protein: 254-286 Range on HMM: 1-33/33 Sequence Identity: 36% (12 aa) HGETALHLAAGYGHVDILEYLQAKGASIDVADK .|.|.||||. .||......| .||.... |. DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD |
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Kinase | DAPK.AA | Ank | 353-385 | 42 | 4.8e-08 | 33.26 | Pfam | 1-33 (33) | Show / Hide |
Range on Protein: 353-385 Range on HMM: 1-33/33 Sequence Identity: 42% (14 aa) DGETTLLCAAARGHLDIVKILVEAGALLNTIDK ||.| | .|. .||...|| |...|| .| |. DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD |
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Kinase | DAPK.AA | Ank | 452-484 | 36 | 5.9e-07 | 29.35 | Pfam | 1-33 (33) | Show / Hide |
Range on Protein: 452-484 Range on HMM: 1-33/33 Sequence Identity: 36% (12 aa) HKNSALHMAARGGHIEVVRYLCLAGALIHQRNQ . ...||.|.| ||.|||..| .|| .. .. DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD |
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Kinase | DAPK.AA | Ank | 287-319 | 39 | 1.6e-05 | 24.15 | Pfam | 1-33 (33) | Show / Hide |
Range on Protein: 287-319 Range on HMM: 1-33/33 Sequence Identity: 39% (13 aa) TGETPLHVAGRYGQVEAVQYLCDQAVNSNLADE |.||||.| |.|..| |..| .. . |. | DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD |
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Kinase | DAPK.AA | Ank | 419-451 | 36 | 0.000348 | 19.35 | Pfam | 1-33 (33) | Show / Hide |
Range on Protein: 419-451 Range on HMM: 1-33/33 Sequence Identity: 36% (12 aa) LGDTPLNVACKEGALDLVEMLHAVGAKRDILNR |.||| .||. | .. |.|| || .. .. DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD |
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Kinase | DAPK.AA | Pkinase_Tyr | 57-105 | 30 | 0.002743 | 11.76 | Pfam | 46-98 (270) | Show / Hide |
Range on Protein: 57-105 Range on HMM: 46-98/270 Sequence Identity: 30% (16 aa) KREDIVREVSILEEL-SHDNIISLHDAFE-LQKE--VVLILELVTGGELFHYL .||| ||..|. .| .|.||..|. . .. . ...|.. .| | .|| CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL |
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Kinase | DAPK.AA | Pkinase_Tyr | 13-29 | 41 | 0.17234 | 5.67 | Pfam | 1-17 (270) | Show / Hide |
Range on Protein: 13-29 Range on HMM: 1-17/270 Sequence Identity: 41% (7 aa) YQIGEDIGSGQFSEVKK ..|. .|.|.| ||.| ITFGKKLGEGAFGEVYK |
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Kinase | DAPK.AA | Ank | 485-505 | 42 | 0.694139 | 7.45 | Pfam | 1-21 (33) | Show / Hide |
Range on Protein: 485-505 Range on HMM: 1-21/33 Sequence Identity: 42% (9 aa) DGLTASQLASLEGHEDVADVL || |. ||.. ||..|. | DGFTPLHLACRCGHTEVVKML |
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ROC | DAPK.AA | ROC | 528-781 | 14 | 7.3e-18 | 56.85 | In-house | 1-215 (215) | Show / Hide |
Range on Protein: 528-781 Range on HMM: 1-215/215 Sequence Identity: 14% (41 aa) LHRIRIKVLGQSGVGKTALIDSLKCGYFRGLFRRSRSNISLIGSSSNGRSSPRSPRSPRSPLTPMFGNGKKMDGGRFFMESLKRKQLSSTSSSFDVDSEV ...... .|| ||||| |. .|... | . |. . . CNEMKLMLCGQGGVGKTSLCKQLMHDKFSDCSCYSC---------------------------------------------------------DKGNHPT TRGIE-FTHGTIPGA----------GDFTFLEFSGEDTYHTAYPHFLSDEGAIHLVVFSLDD---MFEEQ----LAQ--VTYWMNFLRSQLPATEPVGYC | ||| .... ..| . .| | . || . .||. ...|.|... . .... . . . ||..|..| | |. THGIEPIQQWVLDCKDMMFRKKEDEIKFNVWDFGGQEIYHATHQFFLTNHRSVYLLVWDCRTKCCDGQPEMIVRECNYELEYWLRFIKSRGPQSEH-HCM GKYRQQPKIALVATHADHTQCPKQP----------TGELISGEGNIVLYQTKRLFGRLFD----ICDVLFVMDANSAQS-KDVKMLRTH .. ... .|.||.| . . . .| . |.. . | .. ....... |....||.| QP----SPVIIVGTHWDKVPRQDNKVYQHKQCCRMWQKL------------RNKFPNICHSWMQIEHYQGFFHVDCETGCKGIDKLRHH |
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Kinase | DAPK.AA | RSK | 533-543 | 72 | 0.328679 | 0.63 | In-house | 1-11 (278) | Show / Hide |
Range on Protein: 533-543 Range on HMM: 1-11/278 Sequence Identity: 72% (8 aa) IKVLGQSGVGK .||||| |.|| LKVLGQGGYGK |
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ROC | DAPK.AA | ROC | 809-1062 | 14 | 2.1e-17 | 55.34 | In-house | 1-215 (215) | Show / Hide |
Range on Protein: 809-1062 Range on HMM: 1-215/215 Sequence Identity: 14% (41 aa) LHRIRIKVLGQSGVGKTALIDSLKCGYFRGLFRRSRSNISLIGSSSNGRSSPRSPRSPRSPLTPMFGNGKKMDGGRFFMESLKRKQLSSTSSSFDADSEV ...... .|| ||||| |. .|... | . |. . . CNEMKLMLCGQGGVGKTSLCKQLMHDKFSDCSCYSC---------------------------------------------------------DKGNHPT TRGIE-FTHGTIPGA----------GDFTFLEFSGEDTYHTAYPHFLSDEGAIHLVVFSLDD---MFEEQ----LAQ--VTYWMNFLRSQLPATEPVGYC | ||| .... ..| . .| | . || . .||. ...|.|... . .... . . . ||..|..| | |. THGIEPIQQWVLDCKDMMFRKKEDEIKFNVWDFGGQEIYHATHQFFLTNHRSVYLLVWDCRTKCCDGQPEMIVRECNYELEYWLRFIKSRGPQSEH-HCM GKYRQQPKIALVATHADHTQCPK-------QPT--GEMISGEGNIVLYQTKRLFGRLFD----ICDVLFVMDANSAQS-KDVKMLRTH .. ... .|.||.| . |. ... . |.. . | .. ....... |....||.| QP----SPVIIVGTHWDKVPRQDNKVYQHKQCCRMWQKL-----------RNKFPNICHSWMQIEHYQGFFHVDCETGCKGIDKLRHH |
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Kinase | DAPK.AA | COR | 1063-1204 | 15 | 3.5e-15 | 45.36 | In-house | 1-184 (434) | Show / Hide |
Range on Protein: 1063-1204 Range on HMM: 1-184/434 Sequence Identity: 15% (29 aa) ISSLRNSILK-------VEAPVSVLCEAVASALPAWR---RTFVNFPVLTWQQFSEGIHASINP--------LAGQAHLREVGRQLHLMGEVQCFG---- | . .|.. .. || .... ..| ..| . ..|...|..|.. . .| . . |. | ..|| .|.. |. IRKTAKKIKHKQMFEDYMCQPVPQSWWKCKQKLEEMRKWMNRHNEKPWMSWKEFCQICQEHGPPKRLRHQNIIIDEDELHTVAMYLHDLGHIIHFKIWDH SELLQEVIVIEPTWLCSGIIGRLLSHDATE-----QPEGQ-YSIHYIQSLFP---------------DTDAMDISQLMEAMDICV . |....|..| |.| .......| . . | .. . .. ... |.|. .. .|||....|. DPMLKDFVVLDPQWFCQ-MMYHIFNHKESRCFHKLHNKGIFFTHQDLEKIWNPPCRHNPHMNWRRYPDHDHEYLVELMEKFELCY |
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Kinase | DAPK.AA | RSK | 814-824 | 72 | 0.328679 | 0.63 | In-house | 1-11 (278) | Show / Hide |
Range on Protein: 814-824 Range on HMM: 1-11/278 Sequence Identity: 72% (8 aa) IKVLGQSGVGK .||||| |.|| LKVLGQGGYGK |
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COR | DAPK.AA | COR | 1250-1415 | 18 | 2.4e-15 | 45.89 | In-house | 248-434 (434) | Show / Hide |
Range on Protein: 1250-1415 Range on HMM: 248-434/434 Sequence Identity: 18% (36 aa) LPSGLFSRIQMSLRRNFQQDM----EDTTDNELVMWRNGAKCSSGSI---EGLISMTNDECAIEIKVRGYNDTRQG-CFIFLEDLVHLVKHVLVDSY--P ||.|...| | | . . ... | . | . ||||.. . . |.|... |....| | ||| |. . | .. . ...|.. ... | LPAGFWPRFQVRLHHFIHDMFKCFYERSC-CEWMYWRNGMVLKWEGHNKNEALVKCDNHDNKIYITVRGCQDCWIDMCCQLWQIIRQHIQHIHNSWWPWP GLP-------LNMEVLSPIQLSSHEK-TIM--VYNACSLLRLQLRTERTVENPISN-QEEDFVDIFCFGSE---SVESNLIAGVDL-HLSE ||. .. ....| .. |. . |. ...|.. . .... .| .. .. | .. |.. . | .. .| . ..|. GLQYQCQHWVCREWIPCPHCIQDHWDTCCDICYYQYDWCIRAEEMGMDSYPCPKCDQYCDAFEMMCCYQHHWHYSHDQ---NGQWIQRISD |
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Death | DAPK.AA | Death | 1422-1508 | 25 | 8.1e-11 | 38.57 | Pfam | 1-87 (87) | Show / Hide |
Range on Protein: 1422-1508 Range on HMM: 1-87/87 Sequence Identity: 25% (23 aa) RQISMLLDPPDPMGKDWCLLAVGLGL-TEKIPMLDTLNRRCGPDESDSPTERLLQEWGKE--ETNSVGVLLNKVKDLGREDVLRVLMQGS .... ||||....||||. || ||. ..| . . . |. . |.|...|. | . .|. |. ...|| |..... . . QKLCRLLDPDHHPGKDWRRLARKLGMSDNEIDQIEHD---QNPHDLRSQTYQMLWKWEQRHGKNATVDHLIEALRKMGRRDCAEKIQSWL |