Gene PSKH (Sea Urchin)

PSKH

Species: Sea Urchin
Alias: Spk338, PSKH, SpPSKH1, SPU_023309
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: CAMK
Family: PSK

Sequence

Name Sequence Type Origin Length Description Download
PSKH.AA Protein None 663 None Fasta, JSON
PSKH.kin_dom Protein Kinase Domain None 256 None Fasta, JSON

Protein domain

Protein domains of PSKH.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase PSKH.AA PSK 65-320 72 1.1e-213 689.74 In-house 1-258 (258) Show / Hide 
Range on Protein: 65-320
Range on HMM: 1-258/258
Sequence Identity: 72% (186 aa)

YDIKALIGTGTYSRVVRVEHRSTRQPYAIKMVEKK-RDGKQFWEVELTILRRVRHTNIIQLLEVYDGKDRIYMIMELATGGELFDRIVTRGNFTERDATR
||||||||.|..|||||||||.|||||||||||.| |.|..|.|.||.|||||||..||||.||....||.||.||.|||||.|||||..|.||||||||
YDIKALIGKGSFSRVVRVEHRVTRQPYAIKMVETKCREGREFCENELNILRRVRHPYIIQLMEVFETQDRVYMVMEMATGGEMFDRIVAKGRFTERDATR

VLHMVLDAMRYLHGLGITHRDLKPENLLYYHPGNESKIMITDFGLASFRKTSENNMMRTICGTPEYISPEILLRKPYTQSVDLWAIGVVAYILLSX-LSL
||.||||.|||||.|.||||||||||||||||||||||||||||||..||.|...||.|.|||||||.||.|||||||||||.||.||.||||.|  ...
VLQMVLDGMRYLHALRITHRDLKPENLLYYHPGNESKIMITDFGLAYQRKKSNDWMMKTTCGTPEYIAPEVLLRKPYTQSVDMWAVGVIAYILMSGIMPF

QDNLRTLTYRKVLTIRWN*LGSPWKDVSPAGKDFIDKLLLINQSERMTATQALKHPWI
.|..||..||..||...| .|.||..||...||||||||.|||.|||||.||.||||.
DDDCRTRLYRHILTGKYNYYGQPWPSVSHLAKDFIDKLLEINQGERMTASQAMKHPWV
Kinase PSKH.AA CAMK1 65-257 45 3.5e-105 306.7 In-house 1-210 (276) Show / Hide 
Range on Protein: 65-257
Range on HMM: 1-210/276
Sequence Identity: 45% (95 aa)

YDIKALIGTGTYSRVVRVEHRST---RQPYAIKMVE-KKRDGK------QFWEVELTILRRV---RHTNIIQLLEVYDGKDRIYMIMELATGGELFDRIV
| ..  ||.|. | |....|..|    ..||||. . ||   |      .  | |. |...|    | |||.. |.|. .. .|..||| ||||||||||
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV

TRGNFTERDATRVLHMVLDAMRYLHGLGITHRDLKPENLLYYHPGNESKIM--ITDFGLASFRKTSENNMMRTICGTPEYISPEILLR---KPYTQSVDL
 .||.||.|| .. . .|.|  |.| .|| |||||||||||| . ..|||.  | ||||. . .  || .| | ||||.|. ||.| .   ||| ...|.
EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDEN-LMKTACGTPGYVAPEVLECKKDKPYDKACDM

WAIGVVAYILL
| |||. ||||
WSIGVITYILL
Kinase PSKH.AA CAMK 70-320 22 3.2e-104 336.78 In-house 1-425 (425) Show / Hide 
Range on Protein: 70-320
Range on HMM: 1-425/425
Sequence Identity: 22% (97 aa)

LIGTGTYSRVVRVEHRSTR------------QPYAIKMVEKK-----------------------------RDGKQFWEVELTILRR-------VRHTNI
 .|.|... | ...|..|             | .|||...||                                ... . |. |...       ..| ||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IQLLEVYDG-------------------KDRIYMIM---ELATGGEL----FDRIVTRGN---------------FTERDATRVLHMVLDAMRYLHGLGI
|.|.|||.                    ....||.|   |...||||    ||.|| .|.               ||||.| |. . ...|..|.| ..|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

THRDLKPENLLYYHPGNES--------------KIMITDFGLASFRKTSE----------------------NNMMRTICGTPEYIS-PEILLR------
 ||||||||.|. . ...|              .| |.|||.| . . .|                      . .|.| ||||||.. ||.|..      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------KPYTQSVDLWAIGVVAYILLSX-LSLQDN-------------LRTLTYRKVLTIRWN*LGSP------------WKDVSPA--------GKD
        ..|....| |..||. ||.|.  .  ..                  ...|... ...   ..            |.|.|           ||
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

FIDKLLLINQSERMTATQALKHPWI
.| |.|  . ..|||..|.|.|||.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase PSKH.AA S_TKc 65-320 32 1.5e-89 304.7 SMART 1-231 (231) Show / Hide 
Range on Protein: 65-320
Range on HMM: 1-231/231
Sequence Identity: 32% (88 aa)

YDIKALIGTGTYSRVVRVEHRSTRQPYAIKMVEKKRDGKQFWEVELTILRRVRHTNIIQLLEVYDGKDRIYMIMELATG--GELFDRIVTRGN------F
|.|  .|| |....| .. |..| . .|||..       .  . |. ||.. .| ||..|..|..  |..||.||.. |  |.|||.|. ||       |
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

TERDATRVLHMVLDAMRYLHGLGITHRDLKPENLLYYHPGNESKIMITDFGLASFRKTSENNMMRTICGTPEYISPEILLRKPYTQ-SVDLWAIGVVAYI
.| .| .... ...|. |.| .|| ||||||||.|  .      |.|.||||| .         .|.||||.|..||.|   .|.  ..| |..|.. |.
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

LLSXLSLQDNLRTLTYRKVLTIRWN*LGSPWKDVSPAGKDFIDKLLLINQSERMTATQALK-------HPWI
.|.   . .    ....|..              || .||||.|.|  . ..|.|| .||.       |||.
MLCGYPPFP-QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase PSKH.AA Pkinase 65-320 29 4.1e-82 283.9 Pfam 1-293 (293) Show / Hide 
Range on Protein: 65-320
Range on HMM: 1-293/293
Sequence Identity: 29% (89 aa)

YDIKALIGTGTYSRVVRVEHRSTRQPYAIKMVEKKRDGKQFWEV-----ELTILRRVRHTNIIQLLEVYDGKDRIYMIMELATGG----ELFDRIV--TR
| |.  || |....| .  |..|.. .|.| ..|... .....      |. |..|..| ||..|....  ||.|||.||.. ||    .|||.|    .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GNF--TERDATRVLHMVLDAMRYLHGLGITHRDLKPENLLYYHPGNE-SKIMITDFGLAS-FRKTSENNMMRTICGTPEYISPEILL-RKPYTQSVDLWA
|.|  .|... ...  .| .. |.|  || ||||||||.|. . |.  ... |.|||||  |. .  |  | |.||||.|..||... ...|...|| |.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

IGVVAYILLSX-LSLQDN----LRTLTYRKVLTIRWN*LGSPWKDVS--------------------PAGKDFIDKLLLINQSERMTATQALKHPWI
.|.. |..|.  .  ..          . ..  |..  | ..|   .                    ...||||...|  . ..| ||.|.|.|||.
CGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase PSKH.AA Ciliate-E2a 65-258 36 5.6e-74 217.15 In-house 1-211 (275) Show / Hide 
Range on Protein: 65-258
Range on HMM: 1-211/275
Sequence Identity: 36% (77 aa)

YDIKALIGTGTYSRVVRVEHRSTRQPYAIKMVEKK----RDGKQFWEVELTILRRVRHTNIIQLLEVYDGKDRIYMIMELATGGELFDRIVTRGNFTER-
|... .||.|.. .|. ..|. | . .|.| ..||     .||.. . |. |.|...| |||.| ||| ... .|..||.  ||||.|.|.  ..|.|  
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEEI

-DATRVLHMVL-DAMRYLHGLGITHRDLKPENLLYY--HPGNE--SKIMITDFGLASFRKTSENNMMRTICGTPEYISPEILLRKP------YTQSVDLW
 .. ... . | ..  |.| ..| ||||||||.|.    . .   |.|.| ||||| | .. |.. | ..|||| |. ||.|  |       |....|.|
QEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDMW

AIGVVAYILLS
 .||. ||||.
SCGVIFYILLC
Kinase PSKH.AA CAMKL 65-257 33 3.5e-73 232.86 In-house 1-230 (297) Show / Hide 
Range on Protein: 65-257
Range on HMM: 1-230/297
Sequence Identity: 33% (77 aa)

YDIKALIGTGTYSRVVRVEH-RSTRQPYAIKMVEKKRDGKQFWEV----------------ELTILRRVR---HTNIIQLLEVYDGKDR------IYMIM
|.|   .|.|... |   .| | |.. .|||...||.  .  |                  |  |.....   | |||.|.||.. ..       ||..|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELATGGE--LFDRIVTRGN----FTERDATRVLHMVLDAMRYLHGLGITHRDLKPENLLYYHPGNESKIMITDFGLASF-RK--TSENNMMRTICGTPEY
|.. |||  |||.|| .|.    ..|..| |    ...|. |.| .|| |||.||||.|  . ||. .| |.|||.. . |.    ......| ||.|.|
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

ISPEILLR--KPYT-QSVDLWAIGVVAYILL
 .|||...  |||  . || |..||. | ..
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMV
Kinase PSKH.AA RAD53 65-258 32 1.1e-72 215.62 In-house 1-236 (305) Show / Hide 
Range on Protein: 65-258
Range on HMM: 1-236/305
Sequence Identity: 32% (78 aa)

YDIKALIGTGTYSRVVRVEHRSTRQPYAIKMVEKKR---------DGKQFWEVELTILRRVRHTNIIQLLEVYDGK-DRIYMIMELATGGELFDRIVTRG
|..   .|.| .. | ..  ..|.| .||| ..||.         . .   . |. ||... | .||......| . .  ||..||.||||||..|| ..
YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNK

N----FTERDATRVLHMVLDAMRYLHGLGITHRDLKPENLLYYHPGNES---------------KIMITDFGLASFRKTSENNMMRTICGTPEYISPEIL
     |.| .. . .   .|| .||| .||.|||||||| |. |.. |                .| ||||||..|  ..|  .|.| |||| |  ||..
RCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKF--VGEGSFMKTMCGTPQYVAPEVI

LRK---------------PYTQSVDLWAIGVVAYILLS
. |                || .||.| .|.. ||.|.
TSKGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLC
Kinase PSKH.AA Ciliate-E2 65-320 22 8.2e-71 241.57 In-house 1-365 (365) Show / Hide 
Range on Protein: 65-320
Range on HMM: 1-365/365
Sequence Identity: 22% (87 aa)

YDIKALIGTGTYSRVVRVEHRSTRQPYAIK---------------------MVEKKRDGKQFWEVELTILRRVR----------------HTNIIQLLEV
|..  .||.|... | ......... .|||                     |  .| ....... |. |.|...                | |||.. |.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YD--GKDRIYMIMELATGGELFDRIVTR-----------GNFTERDATRVLHMVLD---------------AMRYLHGLG-ITHRDLKPENLLYYHPGNE
.    .. ||..||.. ||.|||.|  .           ..|||. . ..   .|.               |..|||  . | |||.||||.|.      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

SKIMITDFGLASFRKTSEN------------------------------NMMRTICGTPEYISPEILLRKP---------YTQSVDLWAIGVVAYILLSX
  | |.||||. . .....                              || .||||||.| .|||| .|.         |. ..|.|..||. |..|. 
--IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG

LSLQDNLRTLTYRKVLTIRWN*LGSP--------------------WKDVSPAGKDFIDK----LLLINQSERMT-ATQALKHPWI
                 .. .  .                      ||..|. .||.| |    .|  ....|.| . |.|.|||.
KPPF-------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase PSKH.AA DCAMKL 65-257 37 6.2e-70 216.58 In-house 1-213 (279) Show / Hide 
Range on Protein: 65-257
Range on HMM: 1-213/279
Sequence Identity: 37% (82 aa)

YDIKALIGTGTYSRVVRVEHRSTR-QPYAIKM-----------------VEKKR-DGKQFW-EVELTILRRVRHTNIIQLLEVYDGKDRIYMIMELATGG
|.| ..|| |  . |  . ||.|. . || |.                 ..|..  || .  . |. |.....|..|||| |..| .. .|..||...||
YQIGRIIGDGNFAVVHECRHRETGDHKYAMKIRYQSTLQFSFPSKFFQQIDKRKCKGKEHMIDNEVSIMQKIKHPHIIQLYEHWDTETHYYLVMEYVQGG

ELFDRIVTRGNFTERDATRVLHMVLDAMRYLHGLGITHRDLKPENLLYYH--PGNESKIMITDFGLASFRKTSENN---MMRTICGTPEYISPEILLRKP
 ||| |.. . |||||| . .. .  |..||| ..| |||.|||||| .    | |  .   |||||    .  |     . |.|||| |. ||||  . 
DLFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDG-EKSLKLCDFGLA----CHVNGDFGPLYTVCGTPTYVAPEILMETG

YTQSVDLWAIGVVAYILL
|   || ||.||. ||||
YGCKVDIWAAGVILYILL
Kinase PSKH.AA CAMK-Unique 65-258 24 1.7e-66 218.5 In-house 1-288 (363) Show / Hide 
Range on Protein: 65-258
Range on HMM: 1-288/363
Sequence Identity: 24% (71 aa)

YDIKALIGTGTYSRVVRVEHRSTRQPYAIKMVEKKRDG--KQFW-------------------EVELTILRRVRHTNIIQLLEV----YDGKD-------
|.   .||.|... | ..  |.|.  .|.|||.|...|  ||                     . |. |...| | |||.|...    .  ..       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------RIYMIMELATGGELFDRIVT--------------------RGNFTE--RDATRVLHMVLDAMRYLHGLGITHRDLKPENLLYYHPGN-----
        ..|..||...||.||| |.                     .| |.|  .|....   .| |  |.| ..| |||||.||.... ...     
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

--------ESKIMITDFGLASFRKTSENN-MMRTICGTPEYISP--------------EILLRKPYTQSV----DLWAIGVVAYILLS
         ..| ..||||.    ... . || |.||||.|..|              |.. . .| | .    |.|..||..|..|.
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLC
Kinase PSKH.AA RSK 67-258 33 4.4e-64 219.21 In-house 1-207 (278) Show / Hide 
Range on Protein: 67-258
Range on HMM: 1-207/278
Sequence Identity: 33% (69 aa)

IKAL--IGTGTYSRVVRVEHRSTRQPYAIKMVEK-KRDGKQF----WEVELTILRRVR-HTNIIQLLEVYDGKDRIYMIMELATGGELFDRIVTRGN---
.| |  .| | .. . ...|. |.| || | ..| |.. .|        | .|| |.. | .|..| .... .. .|.|||.  |||||... ...    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FTERDATRVLHMVLDAMRYLHGLGITHRDLKPENLLYYH-PGNESKIMITDFGLASFRKTSENNMMRTICGTPEYISPEILL---RKP-YTQSVDLWAIG
|.|..|  ..  .  |...|| .|| |||||||| || .   ||  |..||||..  .. ..|... | |.| ||. ||.|    ..  .....|.|  |
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLG

VVAYILLS
|. | .|.
VLMYEMLT
Kinase PSKH.AA CAMK1 286-320 41 9.3e-14 36.31 In-house 241-276 (276) Show / Hide 
Range on Protein: 286-320
Range on HMM: 241-276/276
Sequence Identity: 41% (15 aa)

WKDVSPA-GKDFIDKLLLINQSERMTATQALKHPWI
| ..|    |||| ..|  . ..| |..|.|.||||
WDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase PSKH.AA DCAMKL 286-320 37 2.2e-13 37.48 In-house 245-279 (279) Show / Hide 
Range on Protein: 286-320
Range on HMM: 245-279/279
Sequence Identity: 37% (13 aa)

WKDVSPAGKDFIDKLLLINQSERMTATQALKHPWI
|...| . || | ..|  ..  | || | ..|||.
WDNISDSAKDLISHMLQVDPEKRYTAEQIMQHPWV
Kinase PSKH.AA RAD53 286-320 37 1.2e-12 33.48 In-house 271-305 (305) Show / Hide 
Range on Protein: 286-320
Range on HMM: 271-305/305
Sequence Identity: 37% (13 aa)

WKDVSPAGKDFIDKLLLINQSERMTATQALKHPWI
|...|   ||.|...| ..  .| |. .|| |||.
WDRISEEAKDLIKWMLCVDPEKRYTIDEALNHPWM
Kinase PSKH.AA Ciliate-E2a 286-320 42 2.8e-12 32.49 In-house 241-275 (275) Show / Hide 
Range on Protein: 286-320
Range on HMM: 241-275/275
Sequence Identity: 42% (15 aa)

WKDVSPAGKDFIDKLLLINQSERMTATQALKHPWI
|...| . ||.. |.|  . ..| ||.|||.||| 
WEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase PSKH.AA CAMK-Unique 286-320 28 9.9e-12 34.8 In-house 326-363 (363) Show / Hide 
Range on Protein: 286-320
Range on HMM: 326-363/363
Sequence Identity: 28% (11 aa)

WKD---VSPAGKDFIDKLLLINQSERMTATQALKHPWI
| .   .|...|||..... . .. | .| ..|.|.||
WHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase PSKH.AA TyrKc 65-320 16 5.8e-11 -45.38 SMART 1-280 (280) Show / Hide 
Range on Protein: 65-320
Range on HMM: 1-280/280
Sequence Identity: 16% (49 aa)

YDIKALIGTGTYSRVVRVEHRSTRQPYAIKMVEKKRDGKQFWEVELTILRRV--RHTNIIQLLEVYDGK-------DRIYMIMELATGGELFDRIVTRGN
   .  .| | . .|.. . .   .. |.||. .    ..    |. |....  .| ||..|. |   .       . ....||.. .| | |..  ...
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

-FTERDATRVLHMVLDAMRYLHGLGITHRDLKPENLLYYHPGNESKIMITDFGLASFRKTS-------ENNMMRT-ICGTP----EYISPEILLRKPYTQ
 .. .|     . . . |.|||  .. ||||   | |. ...    . |.||||. . .         .  ....  .|         .|| .  . .| 
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

SVDLWAIGVVAYILLSX------------LSLQDNLRTLTYRKVLTIRWN*LGSPWKDVSP-----AGKDFIDKLLLINQS---ERMTATQALKHPWI
  | |. ||. . ...             .| |. .. .  .. . .  | .        |     . ..  .  .   .    .| | ..   |  .
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY--------PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase PSKH.AA Pkinase_Tyr 65-185 23 7.9e-10 33.91 Pfam 1-137 (270) Show / Hide 
Range on Protein: 65-185
Range on HMM: 1-137/270
Sequence Identity: 23% (33 aa)

YDIKALIGTGTYSRVVRVEHR----STRQPYAIKMVEKKRDGKQ-----FWEVELTILRRV-RHTNIIQLLEVYD-GKDR--IYMIMELATGGELFDRIV
  .   .| | . .|.. . .    .|..| |.||.  . . .|     | . |. |..   .| ||..|. |    ..   ||..||.. .| | |   
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

T----RGNFTERDATRVLHMVLDAMRYLHGLGITHRDL
.    ....|  |     . . ..| ||.  .. ||||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL
Kinase PSKH.AA RSK 277-320 28 4.1e-09 29.83 In-house 227-278 (278) Show / Hide 
Range on Protein: 277-320
Range on HMM: 227-278/278
Sequence Identity: 28% (15 aa)

IRWN*--LGSP-WKDVSPAGKDFIDKLLLINQSERMT-----ATQALKHPWI
|. .   |..| |. .|.. ||.| |.|  . . | .     | . ..|||.
IQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase PSKH.AA CAMKL 285-320 38 6.3e-08 21.22 In-house 263-297 (297) Show / Hide 
Range on Protein: 285-320
Range on HMM: 263-297/297
Sequence Identity: 38% (14 aa)

PWKDVSPAGKDFIDKLLLINQSERMTATQALKHPWI
.|..||   .|.| |.|  | ..|.|. | ..||| 
IWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM