Gene Spk384 (Sea Urchin)

Spk384

Species: Sea Urchin
Alias: Spk384, SPU_020864
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: Other
Family: Other-Unique

Sequence

Name Sequence Type Origin Length Description Download
Spk384.AA Protein None 451 None Fasta, JSON
Spk384.kin_dom Protein Kinase Domain None 198 None Fasta, JSON

Protein domain

Protein domains of Spk384.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase Spk384.AA Other-Unique 28-216 8 4.8e-20 65.07 In-house 1-249 (249) Show / Hide 
Range on Protein: 28-216
Range on HMM: 1-249/249
Sequence Identity: 8% (21 aa)

HAVYPESDGSQLFLQLPYMGLGNLESAVKEDGLLSRTDV----------------------------------------------------------INV
.. . .   .  ..|.   .  ...  .|.. . . .|                                                           .  
IKDIGKGTYGRVYKQHHNKKKKYCAKKTKHHKI-HCMDMDNNKREQIYHYQIIHCIFYWTMNHCHLCFCYEHCPNMIFYIMYPWYHHHCECQCQCEHWMN

CRNVLMALEGLHRLGLVHGGVHPRNVLLEQRMEGKMEEE---------EEESCIIANLAEFDFTMTTSETALKGFTSETGMRFTAPEVNCGLQATSQADI
|......|..||. ...|. ..| |....| .. ... .         |. ...| .. .. . | .... . .  ......|. . . . ..  .. ..
CCHMIHNLHHLHNNNHIHCDINPNNIWINQNNIHMCHNCGHNIPTIIIEHQHIKIMDFNNN-N-MMYFAPEF-SCRWCSPETFDYWPLGEKIDQYHFGCY

FACGLLLLWALFPTRVFKVEPDGTPDLEGCNLPPSLTEVLDSMLNYSPSKRPSAAR
. .  ...|.. ...| ...|. ... .  ...... | .....   |...|.. .
HFHMNCQHWIFHYHDV-QHWPPHESPKDI-HILICQCECCHQCM-VNPYQNPNCFY
S_TKc Spk384.AA S_TKc 8-223 15 2.8e-09 -40.83 SMART 1-231 (231) Show / Hide 
Range on Protein: 8-223
Range on HMM: 1-231/231
Sequence Identity: 15% (43 aa)

HTLDKMIA-------YSVIEVP--------------------------ACMKLHAVYPESDGSQLFLQLPYMGL--GNLESAVKEDGL------LSRTDV
 .. . |        | ....                              ||. |. .   . |.. . |..   |.| .  |. |       ..  ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HA

INVCRNVLMALEGLHRLGLVHGGVHPRNVLLEQRMEGKMEEEEEESCIIANLAEFDFTMTTSETALKGFTSETG-MRFTAPEVNCGLQATS-QADIFACG
  ... .. ||| .|..| .|  . | |.|| .                  .. | .            |.  |   . ||||    . .   .|. .||
RFYMYQICCALEYCHSHGIIHRDLKPENILLDE---------------HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCG

LLLLWALF-------PTRVFKVEPDGTPDLEGCNLPPSLTEVLDSMLNYSPSKRPSAARVME-------SAFF
 .|   |        . ..||.             .|.. . .. .|.. |.|||.|  ...         .|
CILYEMLCGYPPFPQMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Spk384.AA RCK 190-223 26 5.3e-09 24.41 In-house 265-298 (298) Show / Hide 
Range on Protein: 190-223
Range on HMM: 265-298/298
Sequence Identity: 26% (9 aa)

CNLPPSLTEVLDSMLNYSPSKRPSAARVMESAFF
.|... . |..  ||.. |.||..|. . .  .|
PNCSQDCIELMEKMLQWDPQKRITAQQALQHPYF
Kinase Spk384.AA CMGC 191-223 27 3.6e-07 18.63 In-house 474-513 (513) Show / Hide 
Range on Protein: 191-223
Range on HMM: 474-513/513
Sequence Identity: 27% (11 aa)

N-------LPPSLTEVLDSMLNYSPSKRPSAARVMESAFF
|       ..| . . |. || | |.||..|.  ..  .|
NHQFKRKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase Spk384.AA CDK 200-223 41 3.7e-07 18.78 In-house 261-284 (284) Show / Hide 
Range on Protein: 200-223
Range on HMM: 261-284/284
Sequence Identity: 41% (10 aa)

LDSMLNYSPSKRPSAARVMESAFF
|..|| | |.|| ||   ... .|
LNKMLCYDPKKRISAEQALQHPYF
Kinase Spk384.AA STE 33-223 14 2e-06 18.71 In-house 106-359 (359) Show / Hide 
Range on Protein: 33-223
Range on HMM: 106-359/359
Sequence Identity: 14% (41 aa)

ESDGSQLFLQLPYMGLGNLESAVKEDGLLSRT-------------DVI-NVCRNVLMA-LEGLHRLGLVHGGVHPRNVLLEQRMEGKMEEEEEESCIIAN
......|.. . ||. | |.. .|. .   ..             ..|  .|| .| . |. ||... .|  . | |.||               . ...
HKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL---------------VKLCD

---LAEFDFTM-------------TTSET--ALKGFTSETGMRFTAPEVNCG------LQATSQADIFACGLLL--------LWAL-FPTRV-------F
    . .. .|             |...    . |        . ||||  .       . . ..||   |...         |.   |.|.       .
FGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP------WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNY

KVEP---------DGTPDLEG------------------CNLPPSLTEVLDSMLNYSPSKRPSAARVME--SAFF
....         .. | |.                    .. |.. . ..  |.. |.|||.|   ..    |.
HMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase Spk384.AA Pkinase 191-223 24 2e-06 24.17 Pfam 261-293 (293) Show / Hide 
Range on Protein: 191-223
Range on HMM: 261-293/293
Sequence Identity: 24% (8 aa)

NLPPSLTEVLDSMLNYSPSKRPSAARVMESAFF
|..... ......|.. |.|||.|. .... .|
NWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase Spk384.AA KIS 202-223 31 8e-06 12.9 In-house 452-473 (473) Show / Hide 
Range on Protein: 202-223
Range on HMM: 452-473/473
Sequence Identity: 31% (7 aa)

SMLNYSPSKRPSAARVMESAFF
|||   ...|..|. .. . ||
SMLHCDIARRIPAEMILCHPFF
Kinase Spk384.AA MAK 198-223 34 9e-06 13.88 In-house 327-352 (352) Show / Hide 
Range on Protein: 198-223
Range on HMM: 327-352/352
Sequence Identity: 34% (9 aa)

EVLDSMLNYSPSKRPSAARVMESAFF
|..  ||.. | ||| |.  ..  .|
ELMKDMLQWDPNKRPTAQQCCKYPYF
Kinase Spk384.AA GSK 198-223 30 2e-05 11.86 In-house 303-328 (328) Show / Hide 
Range on Protein: 198-223
Range on HMM: 303-328/328
Sequence Identity: 30% (8 aa)

EVLDSMLNYSPSKRPSAARVMESAFF
. . ..| | |.||.|. ... . ||
DLISKCLVYDPKKRLSPLEACAHPFF
Kinase Spk384.AA KIS 71-96 42 6.2e-05 10.11 In-house 280-305 (473) Show / Hide 
Range on Protein: 71-96
Range on HMM: 280-305/473
Sequence Identity: 42% (11 aa)

RNVLMALEGLHRLGLVHGGVHPRNVL
| .. .|| .|. | ||.   |||.|
RDIAECLEFVHHCGWVHADLKPRNIL
Kinase Spk384.AA TBCK 50-100 23 8.5e-05 12.99 In-house 62-116 (346) Show / Hide 
Range on Protein: 50-100
Range on HMM: 62-116/346
Sequence Identity: 23% (13 aa)

NLES----AVKEDGLLSRTDVINVCRNVLMALEGLHRLGLVHGGVHPRNVLLEQR
|||       |.  ...   . .    .| .|  .|. ..||...|| | .|  .
NLEDQIEIYAKRHTPKDCSQILCIYYQILCGLSYMHKHHIVHRFLHPHNIYLDDN
Kinase Spk384.AA TBCK 192-223 31 0.000716 9.62 In-house 315-346 (346) Show / Hide 
Range on Protein: 192-223
Range on HMM: 315-346/346
Sequence Identity: 31% (10 aa)

LPPSLTEVLDSMLNYSPSKRPSAARVMESAFF
.. .| . . . |  .|.||||   .||.  |
MCEWLIQIIRKCLQMCPMKRPSPTELMEHPMF
Kinase Spk384.AA STE20 200-223 33 0.000862 10.08 In-house 265-288 (288) Show / Hide 
Range on Protein: 200-223
Range on HMM: 265-288/288
Sequence Identity: 33% (8 aa)

LDSMLNYSPSKRPSAARVMESAFF
.|..|.. |.|||.|   ..  |.
VDKCLQKDPEKRPTASQLLKHPFI
Kinase Spk384.AA STE20 36-87 24 0.006166 6.92 In-house 80-140 (288) Show / Hide 
Range on Protein: 36-87
Range on HMM: 80-140/288
Sequence Identity: 24% (15 aa)

GSQLFLQLPYMGLGNLESAVK---EDGL------LSRTDVINVCRNVLMALEGLHRLGLVH
...|..  .|.| | |  ..|   ..|       ..   .  .||.|| .|. ||. . .|
DDELWIVMEYCGGGSLTDIMKHCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIH
Kinase Spk384.AA Pkinase 35-87 19 0.008905 10.9 Pfam 71-131 (293) Show / Hide 
Range on Protein: 35-87
Range on HMM: 71-131/293
Sequence Identity: 19% (12 aa)

DGSQLFLQLPYMGLG----NLESAVK--EDGLL--SRTDVINVCRNVLMALEGLHRLGLVH
|.. . . ..|.. |     | . ..  ..| .  |  ....... .| .|| .|. | .|
DKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIH
Kinase Spk384.AA Pkinase 145-167 37 5.401149 1.06 Pfam 179-202 (293) Show / Hide 
Range on Protein: 145-167
Range on HMM: 179-202/293
Sequence Identity: 37% (9 aa)

APEVNC-GLQATSQADIFACGLLL
||||   |   .. .|...||..|
APEVIRGGQYYGPKVDMWSCGCIL