Gene Spk364 (Sea Urchin)
Spk364
Sequence
Protein domains of Spk364.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | Spk364.AA | urchA | 92-177 | 61 | 3.3e-70 | 225.69 | In-house | 119-208 (208) | Show / Hide |
Range on Protein: 92-177 Range on HMM: 119-208/208 Sequence Identity: 61% (55 aa) QGLKALHSNGFLCNDLKEDNVLVVE-ESGLWQTKIINLGWASEIATPF---VMPLDEEQIDFYRSCRGCCHIAPECVLDARPCSTSSDVY .|||..|..|||||||||||.||.. |.|.|..|||..|||.....|| .|..|..|..|||.|..||||||||.|||.||||||||| EGLKVMHEKGFLCNDLKEDNCLVRKTEFGRWRAKIIDFGWACPCQMPFPACRMHFDQRQKQFYRYCHRCCHIAPECALDAQPCSTSSDVY |
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| Kinase | Spk364.AA | urch | 92-180 | 50 | 9.5e-54 | 184.88 | In-house | 127-217 (217) | Show / Hide |
Range on Protein: 92-180 Range on HMM: 127-217/217 Sequence Identity: 50% (46 aa) QGLKALHSNGFLCNDLKEDNVLVVE-ESGLWQTKIINLGWASEIATPF-VMPLDEEQIDFYRSCRGCCHIAPECVLDARPCSTSSDVYSLG .|..|.|..|||.|||||||||... ..| |. .|| .||......|| .|....|....|....|.||||||||||..|||..|||||.| HGMMAMHDHGFLHNDLKEDNVLLEKRGHGRWHAVIIDFGWVCTMTMPFKMMHFPDEEMREYMHGHGYCHIAPECVLDGQPCSIASDVYSVG |
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| Kinase | Spk364.AA | urchA | 16-91 | 47 | 4.5e-48 | 153.21 | In-house | 1-85 (208) | Show / Hide |
Range on Protein: 16-91 Range on HMM: 1-85/208 Sequence Identity: 47% (40 aa) LGRGVAGTVFLFRHAVSKIPVAAKLVEYPG---------ECFRNEVRIHQAISGLPWFPTFYGSFDIADDQTVLAMEFVGNKSED |||||.|||.|.||.....|||.|..|.|. |||.||..|||.....||||||||...| |. ..||||.| ... LGRGVYGTVHLYRHRQTDHPVALKVIELPKEYKKMRRKIECFQNEMQIHQVLGCEPWFPTFYGCCEICEDKVGMAMEFCGDEMTG |
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| Kinase | Spk364.AA | urch | 16-91 | 38 | 2.2e-32 | 113.91 | In-house | 1-92 (217) | Show / Hide |
Range on Protein: 16-91 Range on HMM: 1-92/217 Sequence Identity: 38% (36 aa) LGRGVAGTVFLFRHAVSKIPVAAKLVEYPG-----------------ECFRNEVRIHQAISGLPWFPTFYGSFDIADDQTVLAMEFVGNKSED .|||..|.|.|.||. .|.||| | ...| |.|..|...||..|| |.||.||| .|| |...|.|||.|.|... IGRGTYGRVHLYRHRQTKQPVAIKMPCWPQNYTDMNEMEMEEWKANHERFTKEAMVHQLMSGHPYFPKFYGCVDID-DDLCLVMEFIGDKKTG |
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| Kinase | Spk364.AA | urch-unclassified | 92-180 | 34 | 1.9e-19 | 66.08 | In-house | 124-215 (215) | Show / Hide |
Range on Protein: 92-180 Range on HMM: 124-215/215 Sequence Identity: 34% (32 aa) QGLKALHSNGFLCNDLKEDNVLVVEESG--LWQTKIINLGWASEIATP---FVMPLDEEQIDFYRSCRGCCHIAPECVLDARPCSTSSDVYSLG .|..|.|. . | |||| .|.|. . | .|| .| .| .. | . .. |.. |.. |.||| ||. | | ||.|||| HGMHAMHEMDLLHNDLKSNNILLQWCDHDQRWHAYIIDFGMISTMTMPHKQRNFSDHEMRE--YMMGKIYHHMAPEIVLYGQPTSVYSDIYSLG |
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| Kinase | Spk364.AA | urchC | 93-183 | 36 | 1e-11 | 34.01 | In-house | 132-223 (223) | Show / Hide |
Range on Protein: 93-183 Range on HMM: 132-223/223 Sequence Identity: 36% (34 aa) GLKALHSNGFLCNDLKEDNVLVVEESGLWQTKIINLGWASEIATPFVMPLDEEQIDFYRSCRGCCHIAPECVLD--ARPCSTSSDVYSLGRLL | ..|..| | || | |||| | || .| | .| | . . . | ||||| ||| | .||.|| | .| GVHFMHDFGLLHNDIKDDNVLLEHRKERWHGCIIDMGMVSTMAYPPHQRGFNDVMPDHQKLYGFIHIAPE-VLDIDGCQVSVASDIYSVGVIL |
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| S_TKc | Spk364.AA | S_TKc | 10-222 | 19 | 5.7e-10 | -30.7 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 10-222
Range on HMM: 1-231/231
Sequence Identity: 19% (51 aa)
TRCSIELGRGVAGTVFLFRHAVSKIPVAAKLVEYPGECFRNEVRIHQAISGLPWFPTFYGSFDIADDQTVLAMEFVGN---------KSED---------
. ..|.| |.|.. || .. || | . | .|.|..|.. . |. ..|..|. | . ||.... |.
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---EHIRREIQILKK--HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFP
-----------QGLKALHSNGFLCNDLKEDNVLVVEESGLWQTKIINLGWASEIATPFVMPLDEEQIDFYRSCRGCCH-IAPECVLDARPCST-SSDVYS
..|. .||.|.. ||| .|.|. | . ||. | | .. ... | . .||| . . .. ..|..|
EHARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL----------------TTFCGTPWYMAPEVL----GYGKCKCDWWS
LGRLLASIGR--------AMRYDDFEFSSTQIY------LA-DEEQRPTVQEIID-------QLYK
.| .|. .| .. | . | | |.|||. |. .
CGCILYEMLCGYPPFPQMQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
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| Kinase | Spk364.AA | urchB | 54-88 | 51 | 2.2e-07 | 22.86 | In-house | 62-95 (212) | Show / Hide |
Range on Protein: 54-88 Range on HMM: 62-95/212 Sequence Identity: 51% (18 aa) IHQAISGLPWFPTFYGSFDIADDQTVLAMEFVGNK ||| .|. |.|| |.| || | .| ||||.| IHQLMSDSPYFPKFWGTLDI-DNDLCQAQEFVGCK |
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| Kinase | Spk364.AA | urch-unclassified | 51-89 | 33 | 2.9e-07 | 22.22 | In-house | 52-89 (215) | Show / Hide |
Range on Protein: 51-89 Range on HMM: 52-89/215 Sequence Identity: 33% (13 aa) EVRIHQAISGLPWFPTFYGSFDIADDQTVLAMEFVGNKS |...|.. .. | || || ...|. . ..||| |.|. EAMVHRLFADHPYFPRCYGMVKHEDC-PCIVMEFLGDKQ |
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| Kinase | Spk364.AA | urchB | 159-180 | 54 | 6.6e-07 | 21.16 | In-house | 191-212 (212) | Show / Hide |
Range on Protein: 159-180 Range on HMM: 191-212/212 Sequence Identity: 54% (12 aa) IAPECVLDARPCSTSSDVYSLG |||| .|. . | ||||.| | IAPEVILHGQSTSISSDVFSVG |
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| Kinase | Spk364.AA | CAMK | 15-56 | 16 | 0.000104 | 10.32 | In-house | 1-86 (425) | Show / Hide |
Range on Protein: 15-56 Range on HMM: 1-86/425 Sequence Identity: 16% (14 aa) ELGRGVAGTVFLFRHAVSK------------IPVAAKLVEY--------------------------------PGECFRNEVRIHQ .|||| |.|.| .| .. ||.| .. . .|.|..|.. TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMK |
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| Kinase | Spk364.AA | C8 | 93-183 | 20 | 0.000262 | 10.99 | In-house | 135-226 (226) | Show / Hide |
Range on Protein: 93-183 Range on HMM: 135-226/226 Sequence Identity: 20% (20 aa) GLKALHSNGFLCNDLKEDNVLVVEESGLW-QTKIINLGWASEIATPFVMPLDEEQIDFYRSCRGCCHIAPECVLD----ARPCSTSSDVYSLGRLL |. .|. .. |.| .| || .. . |. .| || . .. . | .||| . . . ||..|.| .| GVNYIHCKNIMHRDIKPHNFLVCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNT----CGTWAYFAPEIEKKQDNQYKQYRIQSDLFSVGLVL |
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| Kinase | Spk364.AA | Ciliate-C7 | 92-113 | 54 | 0.000308 | 10.02 | In-house | 113-134 (164) | Show / Hide |
Range on Protein: 92-113 Range on HMM: 113-134/164 Sequence Identity: 54% (12 aa) QGLKALHSNGFLCNDLKEDNVL ||| ||.... |||| || | QGLYYIHSKNCVVNDLKMDNIL |
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| Kinase | Spk364.AA | Ciliate-B1 | 206-221 | 50 | 0.000801 | 9.4 | In-house | 275-290 (290) | Show / Hide |
Range on Protein: 206-221 Range on HMM: 275-290/290 Sequence Identity: 50% (8 aa) DEEQRPTVQEIIDQLY | |.|.|.. ||| |. DPENRITIDQIIDRLM |
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| Kinase | Spk364.AA | urchB | 92-140 | 38 | 0.001131 | 9.43 | In-house | 123-171 (212) | Show / Hide |
Range on Protein: 92-140 Range on HMM: 123-171/212 Sequence Identity: 38% (19 aa) QGLKALHSNGFLCNDLKEDNVLVVEESGLWQTKIINLGWASEIATPFVM .|. .| | | |||| |||| . || | .| | | | KGMMEFHDHGLLHNDLKNDNVLLEKRGHRYHAVIIDFGMVSTITAPLKM |
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| Kinase | Spk364.AA | TK | 160-183 | 37 | 0.002555 | 6.13 | In-house | 353-384 (486) | Show / Hide |
Range on Protein: 160-183 Range on HMM: 353-384/486 Sequence Identity: 37% (12 aa) APECVLDARP--------CSTSSDVYSLGRLL ||||..| .. ..| |||.|.| |. APECLNDRVFSEAEKYGKFTTKSDVWSFGVLM |
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| Kinase | Spk364.AA | urchB | 15-39 | 48 | 0.023128 | 4.68 | In-house | 6-30 (212) | Show / Hide |
Range on Protein: 15-39 Range on HMM: 6-30/212 Sequence Identity: 48% (12 aa) ELGRGVAGTVFLFRHAVSKIPVAAK | ||| | | . || |.| | | EIGRGTYGRVVIARHRQTKVPLAIK |
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| Kinase | Spk364.AA | TK | 205-220 | 43 | 0.028436 | 2.56 | In-house | 471-486 (486) | Show / Hide |
Range on Protein: 205-220 Range on HMM: 471-486/486 Sequence Identity: 43% (7 aa) ADEEQRPTVQEIIDQL .| |.||| ... .|| YDPEDRPTFSQLHEQL |
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| Kinase | Spk364.AA | urch-unclassified | 16-37 | 40 | 0.078082 | 2.7 | In-house | 1-22 (215) | Show / Hide |
Range on Protein: 16-37 Range on HMM: 1-22/215 Sequence Identity: 40% (9 aa) LGRGVAGTVFLFRHAVSKIPVA .| | | ||. || .||. IGKGTFGKVFMMRHQREAVPVK |
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| Kinase | Spk364.AA | urchC | 48-88 | 34 | 0.118561 | 0.87 | In-house | 54-93 (223) | Show / Hide |
Range on Protein: 48-88 Range on HMM: 54-93/223 Sequence Identity: 34% (14 aa) FRNEVRIHQAISGLPWFPTFYGSFDIADDQTVLAMEFVGNK .. | |. | .|. |.|| .|| . | . ||.| | CEKEARVGQMMSTCPYFPRMYGTV-MIDENMCIVTEFIGDK |
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